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Search of human proteins with 63999741
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|63999741 kazrin isoform C [Homo sapiens]
(327 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|65301128 kazrin isoform C [Homo sapiens] 645 0.0
gi|65301130 kazrin isoform B [Homo sapiens] 645 0.0
gi|63999741 kazrin isoform C [Homo sapiens] 645 0.0
gi|63147424 kazrin isoform A [Homo sapiens] 645 0.0
gi|157837985 kazrin isoform E [Homo sapiens] 613 e-176
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 56 4e-08
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 56 5e-08
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 55 9e-08
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 55 9e-08
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 54 1e-07
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 54 1e-07
gi|38044112 restin isoform b [Homo sapiens] 54 2e-07
gi|4506751 restin isoform a [Homo sapiens] 54 2e-07
gi|156104908 myosin heavy chain 6 [Homo sapiens] 54 2e-07
gi|45439327 periplakin [Homo sapiens] 54 2e-07
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 52 6e-07
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 52 9e-07
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 51 1e-06
gi|34577114 cytomatrix protein p110 [Homo sapiens] 51 2e-06
gi|92091575 coiled-coil domain containing 57 [Homo sapiens] 51 2e-06
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 51 2e-06
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 50 2e-06
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 50 3e-06
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 50 3e-06
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 50 3e-06
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 50 3e-06
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 50 4e-06
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 50 4e-06
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 49 5e-06
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 49 5e-06
>gi|65301128 kazrin isoform C [Homo sapiens]
Length = 327
Score = 645 bits (1665), Expect = 0.0
Identities = 327/327 (100%), Positives = 327/327 (100%)
Query: 1 MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD
Sbjct: 1 MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
Query: 61 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE
Sbjct: 61 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
Query: 121 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 180
ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW
Sbjct: 121 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 180
Query: 181 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 240
VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP
Sbjct: 181 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 240
Query: 241 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 300
SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR
Sbjct: 241 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 300
Query: 301 GKQRKSLDPGLFDGTAPDYYIEEDADW 327
GKQRKSLDPGLFDGTAPDYYIEEDADW
Sbjct: 301 GKQRKSLDPGLFDGTAPDYYIEEDADW 327
>gi|65301130 kazrin isoform B [Homo sapiens]
Length = 415
Score = 645 bits (1665), Expect = 0.0
Identities = 327/327 (100%), Positives = 327/327 (100%)
Query: 1 MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD
Sbjct: 89 MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 148
Query: 61 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE
Sbjct: 149 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 208
Query: 121 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 180
ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW
Sbjct: 209 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 268
Query: 181 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 240
VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP
Sbjct: 269 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 328
Query: 241 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 300
SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR
Sbjct: 329 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 388
Query: 301 GKQRKSLDPGLFDGTAPDYYIEEDADW 327
GKQRKSLDPGLFDGTAPDYYIEEDADW
Sbjct: 389 GKQRKSLDPGLFDGTAPDYYIEEDADW 415
>gi|63999741 kazrin isoform C [Homo sapiens]
Length = 327
Score = 645 bits (1665), Expect = 0.0
Identities = 327/327 (100%), Positives = 327/327 (100%)
Query: 1 MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD
Sbjct: 1 MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
Query: 61 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE
Sbjct: 61 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
Query: 121 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 180
ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW
Sbjct: 121 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 180
Query: 181 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 240
VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP
Sbjct: 181 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 240
Query: 241 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 300
SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR
Sbjct: 241 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 300
Query: 301 GKQRKSLDPGLFDGTAPDYYIEEDADW 327
GKQRKSLDPGLFDGTAPDYYIEEDADW
Sbjct: 301 GKQRKSLDPGLFDGTAPDYYIEEDADW 327
>gi|63147424 kazrin isoform A [Homo sapiens]
Length = 421
Score = 645 bits (1665), Expect = 0.0
Identities = 327/327 (100%), Positives = 327/327 (100%)
Query: 1 MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD
Sbjct: 95 MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 154
Query: 61 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE
Sbjct: 155 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 214
Query: 121 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 180
ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW
Sbjct: 215 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 274
Query: 181 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 240
VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP
Sbjct: 275 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 334
Query: 241 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 300
SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR
Sbjct: 335 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 394
Query: 301 GKQRKSLDPGLFDGTAPDYYIEEDADW 327
GKQRKSLDPGLFDGTAPDYYIEEDADW
Sbjct: 395 GKQRKSLDPGLFDGTAPDYYIEEDADW 421
>gi|157837985 kazrin isoform E [Homo sapiens]
Length = 775
Score = 613 bits (1582), Expect = e-176
Identities = 313/313 (100%), Positives = 313/313 (100%)
Query: 1 MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD
Sbjct: 95 MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 154
Query: 61 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE
Sbjct: 155 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 214
Query: 121 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 180
ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW
Sbjct: 215 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEW 274
Query: 181 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 240
VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP
Sbjct: 275 VVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTP 334
Query: 241 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 300
SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR
Sbjct: 335 SDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFAR 394
Query: 301 GKQRKSLDPGLFD 313
GKQRKSLDPGLFD
Sbjct: 395 GKQRKSLDPGLFD 407
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 56.2 bits (134), Expect = 4e-08
Identities = 44/169 (26%), Positives = 81/169 (47%), Gaps = 15/169 (8%)
Query: 10 EESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLY 69
E S+ + ++L +LR Q K Q LA ++ ++ K R+RL+ ++ +Q
Sbjct: 365 ERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQE 424
Query: 70 ATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALR 129
RE++ + + E+ RKE E+ +A +EK +ERE+ +RRQ +E H L+
Sbjct: 425 REQRRREQEEKRRLEELERRRKEEEERRRA-EEEKRRVEREQEYIRRQLEEEQRHLEVLQ 483
Query: 130 SQL-------------DLKDNRMKE-LEAELAMAKQSLATLTKDVPKRH 164
QL +++++R E L+ +L + L +L D + H
Sbjct: 484 QQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPH 532
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 55.8 bits (133), Expect = 5e-08
Identities = 47/161 (29%), Positives = 73/161 (45%), Gaps = 17/161 (10%)
Query: 16 KSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG-------EKTDLVSQMQQL 68
K +L + E ++A ++E R KEAL+ +A RK L+ EK DL Q+Q
Sbjct: 835 KIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAE 894
Query: 69 YATLESREEQLRDFIRNYEQ---------HRKESEDAVKA-LAKEKDLLEREKWELRRQA 118
L EE+ I+N Q R E E+ + A L +K LE E EL+R
Sbjct: 895 QDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI 954
Query: 119 KEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
+ + + +N++K L E+A + +A LTK+
Sbjct: 955 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKE 995
Score = 43.9 bits (102), Expect = 2e-04
Identities = 46/166 (27%), Positives = 73/166 (43%), Gaps = 26/166 (15%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKA----DRKRLKGEK 58
+ + +DLEE+ +A LR + A EL + LQ +K ++ K E
Sbjct: 1172 QKMRRDLEEAT---LQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1228
Query: 59 TDLVSQMQQLY---ATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELR 115
D+ S M+Q+ A LE L D + + +E++ +V L ++ L+ E EL
Sbjct: 1229 DDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELS 1288
Query: 116 RQAKEATDHATALRSQL------------DLKDNRMKELEAELAMA 149
RQ D AL SQL DLK +E++A+ A+A
Sbjct: 1289 RQ----LDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALA 1330
Score = 40.8 bits (94), Expect = 0.002
Identities = 36/157 (22%), Positives = 65/157 (41%), Gaps = 8/157 (5%)
Query: 10 EESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLY 69
EESQ S A L +L + + + E L+ K + K L+ E +DL Q+
Sbjct: 1461 EESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSG 1520
Query: 70 ATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWEL--------RRQAKEA 121
T+ E+ + + + E+A +L E+ + R + E R+ A++
Sbjct: 1521 KTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD 1580
Query: 122 TDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
+ A R+ L + D+ L+AE ++L K
Sbjct: 1581 EEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKK 1617
Score = 39.3 bits (90), Expect = 0.005
Identities = 38/148 (25%), Positives = 70/148 (47%), Gaps = 10/148 (6%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAK-EALQAMKADRKRLKGEKTDL 61
E L + LEE K+ A +Q A+ + +L R + E KA+ +R+ +
Sbjct: 1313 EDLKRQLEEEVKAKN-----ALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSE 1367
Query: 62 VSQMQQLYAT-LESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
V+Q + Y T R E+L + + Q +E+E+AV+A+ + LE+ K L+ + ++
Sbjct: 1368 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIED 1427
Query: 121 A---TDHATALRSQLDLKDNRMKELEAE 145
+ + A + LD K ++ AE
Sbjct: 1428 LMVDVERSNAAAAALDKKQRNFDKILAE 1455
Score = 38.1 bits (87), Expect = 0.011
Identities = 35/149 (23%), Positives = 70/149 (46%), Gaps = 28/149 (18%)
Query: 25 ELRVQLAQKEQELARAKEALQA----MKADRKRLKGEKTDLVSQMQQLYATLESREEQLR 80
E + +LAQ+ QE A EA+ A ++ + RL+ E DL+ +++ A + +++ R
Sbjct: 1388 EAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR 1447
Query: 81 DF---IRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQ------ 131
+F + ++Q +ES+ +++ KE L E ++L+ +E+ +H + +
Sbjct: 1448 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQE 1507
Query: 132 --LDLKDNR-------------MKELEAE 145
DL + K+LEAE
Sbjct: 1508 EISDLTEQLGSSGKTIHELEKVRKQLEAE 1536
Score = 32.3 bits (72), Expect = 0.59
Identities = 26/132 (19%), Positives = 55/132 (41%), Gaps = 7/132 (5%)
Query: 27 RVQLAQKEQELARAKEALQAMKAD----RKRLKGEKTDLVSQMQQLYATL---ESREEQL 79
++QL K +E+ E + M A+ +++L+ E ++L + L TL E +
Sbjct: 912 KIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHAT 971
Query: 80 RDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRM 139
+ ++N + ++ + L KEK L+ + + D L + ++
Sbjct: 972 ENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQV 1031
Query: 140 KELEAELAMAKQ 151
+LE L K+
Sbjct: 1032 DDLEGSLEQEKK 1043
Score = 31.6 bits (70), Expect = 1.0
Identities = 30/130 (23%), Positives = 55/130 (42%), Gaps = 8/130 (6%)
Query: 25 ELRVQLAQKEQELARAK-----EALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQL 79
EL + +KE+ K E + + +L EK L QQ L++ E+++
Sbjct: 958 ELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKV 1017
Query: 80 RDFIRNYEQHRKESEDAVKALAKEKDL---LEREKWELRRQAKEATDHATALRSQLDLKD 136
+ + ++ +D +L +EK + LER K +L K + L + D
Sbjct: 1018 NTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLD 1077
Query: 137 NRMKELEAEL 146
R+K+ + EL
Sbjct: 1078 ERLKKKDFEL 1087
Score = 31.6 bits (70), Expect = 1.0
Identities = 29/157 (18%), Positives = 73/157 (46%), Gaps = 4/157 (2%)
Query: 4 MLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKE-ALQAMKADRKRLKGEKTDLV 62
M+A++L++ Q + + + + L A++ AL+ K ++L+ +L
Sbjct: 1764 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELE 1823
Query: 63 SQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWEL---RRQAK 119
++++ + +R R ++ ++E+ K L + +DL+++ + ++ +RQA+
Sbjct: 1824 NELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAE 1883
Query: 120 EATDHATALRSQLDLKDNRMKELEAELAMAKQSLATL 156
EA + A S+ + + E E +A+ + L
Sbjct: 1884 EAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKL 1920
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 55.1 bits (131), Expect = 9e-08
Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 1/123 (0%)
Query: 10 EESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLY 69
E S+ + ++L +LR Q K Q LA ++ ++ K R+RL+ ++ +Q
Sbjct: 365 ERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQE 424
Query: 70 ATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALR 129
RE++ + + E+ RKE E+ +A +EK +ERE+ +RRQ +E H L+
Sbjct: 425 REQRRREQEEKRRLEELERRRKEEEERRRA-EEEKRRVEREQEYIRRQLEEEQRHLEVLQ 483
Query: 130 SQL 132
QL
Sbjct: 484 QQL 486
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 55.1 bits (131), Expect = 9e-08
Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 1/123 (0%)
Query: 10 EESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLY 69
E S+ + ++L +LR Q K Q LA ++ ++ K R+RL+ ++ +Q
Sbjct: 365 ERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQE 424
Query: 70 ATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALR 129
RE++ + + E+ RKE E+ +A +EK +ERE+ +RRQ +E H L+
Sbjct: 425 REQRRREQEEKRRLEELERRRKEEEERRRA-EEEKRRVEREQEYIRRQLEEEQRHLEVLQ 483
Query: 130 SQL 132
QL
Sbjct: 484 QQL 486
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 54.3 bits (129), Expect = 1e-07
Identities = 36/143 (25%), Positives = 68/143 (47%)
Query: 26 LRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRN 85
L+ QL KE++++ KE +++++AD T L + + T+E +EQ R
Sbjct: 583 LQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDERE 642
Query: 86 YEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAE 145
++ + +K L ++ LL+ + E + +HA++L S KD+R+K LE
Sbjct: 643 KQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIA 702
Query: 146 LAMAKQSLATLTKDVPKRHSLAM 168
L K+ + + K H A+
Sbjct: 703 LEQKKEECLKMESQLKKAHEAAL 725
Score = 43.1 bits (100), Expect = 3e-04
Identities = 53/213 (24%), Positives = 96/213 (45%), Gaps = 17/213 (7%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAK----EALQAMKADRKRLKGE 57
K+ K LE + K E L E +++ A + ARA + +Q ++ + R K E
Sbjct: 692 KDSRLKTLEIALEQKKEECLKM-ESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDE 750
Query: 58 KTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALA--KEKDLLEREKW--- 112
+ +++ +L L+ E + D + + ++ +D K +A K K+ +E++K
Sbjct: 751 SSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQM 810
Query: 113 --ELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLA----TLTKDVPKRHSL 166
E RR+ D + L+ L KD+R++ELE L + Q A L ++ R +
Sbjct: 811 LEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNA 870
Query: 167 AMPGETVLNGNQEWVVQADLPLTAAIRQSQQTL 199
E +L E V Q + A + +QQ+L
Sbjct: 871 EKQVEELLMA-MEKVKQELESMKAKLSSTQQSL 902
Score = 36.2 bits (82), Expect = 0.041
Identities = 35/185 (18%), Positives = 77/185 (41%), Gaps = 24/185 (12%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
E L ++L + A L+ ++ Q +QEL+R L A++ + L + +D
Sbjct: 441 EQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSK 500
Query: 63 SQMQQLYATLESREEQ----------LRDFIRNYEQHRKESEDAVKALAKEK-------- 104
++ L +L ++E++ LR + E + ++ +A+EK
Sbjct: 501 QHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIH 560
Query: 105 ------DLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
D+ ER+ L+++ + + Q+ R+K L+A+ +L TL +
Sbjct: 561 DLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEE 620
Query: 159 DVPKR 163
+ ++
Sbjct: 621 ALAEK 625
Score = 36.2 bits (82), Expect = 0.041
Identities = 44/222 (19%), Positives = 92/222 (41%), Gaps = 22/222 (9%)
Query: 9 LEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQL 68
+EE + V E + LAQ+E A++ ++ + +++K E + +++
Sbjct: 839 IEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSST 898
Query: 69 YATLESREEQLRDFIRNYEQHRKE----SEDAVKALAKEKDLLEREKWELRRQAKEATDH 124
+L +E L + +H +E ++A+ A EKD EL K+ +
Sbjct: 899 QQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKD-ANIALLELSSSKKKTQEE 957
Query: 125 ATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQA 184
AL+ + KD +++L+ + + +A +D + S + +T + + ++Q
Sbjct: 958 VAALKRE---KDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHS--NQTNHKPSPDQIIQP 1012
Query: 185 DLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVI 226
L L +S+ LY H + CH R P ++
Sbjct: 1013 LLELDQ--NRSKLKLYIGH----------LTTLCHDRDPLIL 1042
Score = 35.8 bits (81), Expect = 0.053
Identities = 38/143 (26%), Positives = 64/143 (44%), Gaps = 17/143 (11%)
Query: 26 LRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRN 85
LR L + E + K+ L A K+L L S+ AT E E R +
Sbjct: 284 LRKTLEEMELRIETQKQTLNARDESIKKLLEM---LQSKGLSAKATEEDHERTRR--LAE 338
Query: 86 YEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHAT--ALRSQLDLKDNR----- 138
E H E ++ KE +L E + R+ + A D A AL++ +++KD++
Sbjct: 339 AEMHVHHLESLLEQKEKENSMLREE---MHRRFENAPDSAKTKALQTVIEMKDSKISSME 395
Query: 139 --MKELEAELAMAKQSLATLTKD 159
+++LE E+ M K + A T++
Sbjct: 396 RGLRDLEEEIQMLKSNGALSTEE 418
Score = 35.0 bits (79), Expect = 0.091
Identities = 39/176 (22%), Positives = 70/176 (39%), Gaps = 28/176 (15%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKA-------DRKRLK 55
+ L + L+E + K+ + EL Q+ + +++A K Q K + +R +
Sbjct: 759 DRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRRE 818
Query: 56 GEKTDLVSQMQQLYATLESREEQLRDFIRNYEQ------------------HRKESEDAV 97
D Q+Q + R E+L + +R Q K+ E+ +
Sbjct: 819 DNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELL 878
Query: 98 KALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 153
A+ K K LE K +L + + T L +L+ R K LE L M +++L
Sbjct: 879 MAMEKVKQELESMKAKLSSTQQSLAEKETHL---TNLRAERRKHLEEVLEMKQEAL 931
Score = 33.1 bits (74), Expect = 0.35
Identities = 23/91 (25%), Positives = 45/91 (49%), Gaps = 5/91 (5%)
Query: 60 DLVSQMQQLYA----TLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELR 115
DL ++Q L + + E REE+++ + Y H K ++ V+ L +E E + EL+
Sbjct: 400 DLEEEIQMLKSNGALSTEEREEEMKQ-MEVYRSHSKFMKNKVEQLKEELSSKEAQWEELK 458
Query: 116 RQAKEATDHATALRSQLDLKDNRMKELEAEL 146
++A ++ +L KD + L+ +L
Sbjct: 459 KKAAGLQAEIGQVKQELSRKDTELLALQTKL 489
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 54.3 bits (129), Expect = 1e-07
Identities = 36/143 (25%), Positives = 68/143 (47%)
Query: 26 LRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRN 85
L+ QL KE++++ KE +++++AD T L + + T+E +EQ R
Sbjct: 555 LQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDERE 614
Query: 86 YEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAE 145
++ + +K L ++ LL+ + E + +HA++L S KD+R+K LE
Sbjct: 615 KQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIA 674
Query: 146 LAMAKQSLATLTKDVPKRHSLAM 168
L K+ + + K H A+
Sbjct: 675 LEQKKEECLKMESQLKKAHEAAL 697
Score = 43.1 bits (100), Expect = 3e-04
Identities = 53/213 (24%), Positives = 96/213 (45%), Gaps = 17/213 (7%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAK----EALQAMKADRKRLKGE 57
K+ K LE + K E L E +++ A + ARA + +Q ++ + R K E
Sbjct: 664 KDSRLKTLEIALEQKKEECLKM-ESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDE 722
Query: 58 KTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALA--KEKDLLEREKW--- 112
+ +++ +L L+ E + D + + ++ +D K +A K K+ +E++K
Sbjct: 723 SSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQM 782
Query: 113 --ELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLA----TLTKDVPKRHSL 166
E RR+ D + L+ L KD+R++ELE L + Q A L ++ R +
Sbjct: 783 LEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNA 842
Query: 167 AMPGETVLNGNQEWVVQADLPLTAAIRQSQQTL 199
E +L E V Q + A + +QQ+L
Sbjct: 843 EKQVEELLMA-MEKVKQELESMKAKLSSTQQSL 874
Score = 36.2 bits (82), Expect = 0.041
Identities = 44/222 (19%), Positives = 92/222 (41%), Gaps = 22/222 (9%)
Query: 9 LEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQL 68
+EE + V E + LAQ+E A++ ++ + +++K E + +++
Sbjct: 811 IEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSST 870
Query: 69 YATLESREEQLRDFIRNYEQHRKE----SEDAVKALAKEKDLLEREKWELRRQAKEATDH 124
+L +E L + +H +E ++A+ A EKD EL K+ +
Sbjct: 871 QQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKD-ANIALLELSSSKKKTQEE 929
Query: 125 ATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQA 184
AL+ + KD +++L+ + + +A +D + S + +T + + ++Q
Sbjct: 930 VAALKRE---KDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHS--NQTNHKPSPDQIIQP 984
Query: 185 DLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVI 226
L L +S+ LY H + CH R P ++
Sbjct: 985 LLELDQ--NRSKLKLYIGH----------LTTLCHDRDPLIL 1014
Score = 35.8 bits (81), Expect = 0.053
Identities = 38/143 (26%), Positives = 64/143 (44%), Gaps = 17/143 (11%)
Query: 26 LRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRN 85
LR L + E + K+ L A K+L L S+ AT E E R +
Sbjct: 284 LRKTLEEMELRIETQKQTLNARDESIKKLLEM---LQSKGLSAKATEEDHERTRR--LAE 338
Query: 86 YEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHAT--ALRSQLDLKDNR----- 138
E H E ++ KE +L E + R+ + A D A AL++ +++KD++
Sbjct: 339 AEMHVHHLESLLEQKEKENSMLREE---MHRRFENAPDSAKTKALQTVIEMKDSKISSME 395
Query: 139 --MKELEAELAMAKQSLATLTKD 159
+++LE E+ M K + A T++
Sbjct: 396 RGLRDLEEEIQMLKSNGALSTEE 418
Score = 35.0 bits (79), Expect = 0.091
Identities = 39/176 (22%), Positives = 70/176 (39%), Gaps = 28/176 (15%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKA-------DRKRLK 55
+ L + L+E + K+ + EL Q+ + +++A K Q K + +R +
Sbjct: 731 DRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRRE 790
Query: 56 GEKTDLVSQMQQLYATLESREEQLRDFIRNYEQ------------------HRKESEDAV 97
D Q+Q + R E+L + +R Q K+ E+ +
Sbjct: 791 DNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELL 850
Query: 98 KALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 153
A+ K K LE K +L + + T L +L+ R K LE L M +++L
Sbjct: 851 MAMEKVKQELESMKAKLSSTQQSLAEKETHL---TNLRAERRKHLEEVLEMKQEAL 903
Score = 32.3 bits (72), Expect = 0.59
Identities = 27/135 (20%), Positives = 57/135 (42%), Gaps = 4/135 (2%)
Query: 29 QLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQ 88
Q + +Q + KE+L A + L+ E L ++++ L + +Q++D
Sbjct: 467 QFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGT 526
Query: 89 HRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAM 148
E D L D+ ER+ L+++ + + Q+ R+K L+A+
Sbjct: 527 QAGEIHDLKDML----DVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTN 582
Query: 149 AKQSLATLTKDVPKR 163
+L TL + + ++
Sbjct: 583 TDTALTTLEEALAEK 597
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 53.9 bits (128), Expect = 2e-07
Identities = 40/171 (23%), Positives = 79/171 (46%), Gaps = 15/171 (8%)
Query: 5 LAKDLEESQGGKSSEVLSATELRV-QLAQKEQELARAKEAL----QAMKADRKRLKGEKT 59
+ K+ E S+ + L EL++ L + E+++ KE L Q +K E
Sbjct: 763 IEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAV 822
Query: 60 DLVSQMQQLYATLESREEQ----------LRDFIRNYEQHRKESEDAVKALAKEKDLLER 109
+ MQ+ L +EEQ LR+ + + E +E ++ + L K K+ LE
Sbjct: 823 SVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLEN 882
Query: 110 EKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDV 160
+ E+ + + + + T + +L LK+ ++EL+ +L A ++ + L K +
Sbjct: 883 DIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSI 933
Score = 39.7 bits (91), Expect = 0.004
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 18/148 (12%)
Query: 22 SATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQM-------QQLYATLES 74
S ++ V+ Q +QE A+ E ++K L+ + +DL +M Q+L A E
Sbjct: 932 SIEDMTVKAEQSQQEAAKKHEE------EKKELERKLSDLEKKMETSHNQCQELKARYER 985
Query: 75 REEQLR----DFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRS 130
+ + + ++N ++ ++ED +K +E L +E ELR+QA +A TA
Sbjct: 986 ATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTA-ED 1044
Query: 131 QLDLKDNRMKELEAELAMAKQSLATLTK 158
+ + + KE LA + + T K
Sbjct: 1045 AMQIMEQMTKEKTETLASLEDTKQTNAK 1072
Score = 38.1 bits (87), Expect = 0.011
Identities = 39/157 (24%), Positives = 75/157 (47%), Gaps = 9/157 (5%)
Query: 7 KDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQ 66
+D E + K E L A ++V + +KE L + L KA+ + L E D ++++Q
Sbjct: 635 QDSERAAHAKEMEALRAKLMKV-IKEKENSLEAIRSKLD--KAEDQHLV-EMEDTLNKLQ 690
Query: 67 QLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHAT 126
+ A ++ +E ++ N EQ + + A E+ LL+ + LR+ + E
Sbjct: 691 E--AEIKVKELEVLQAKCN-EQTKVIDNFTSQLKATEEKLLDLDA--LRKASSEGKSEMK 745
Query: 127 ALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKR 163
LR QL+ + ++K LE E +++T+++ R
Sbjct: 746 KLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGR 782
Score = 37.4 bits (85), Expect = 0.018
Identities = 36/163 (22%), Positives = 79/163 (48%), Gaps = 15/163 (9%)
Query: 4 MLAKDLEESQGGKSSEVLSATELRV-QLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
ML+ DLE K E L+ E + + ++E++L +AKE L+ A+ ++ G+ + +
Sbjct: 844 MLSSDLE-----KLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQL 898
Query: 63 SQMQQLYATLESREEQLRDFIRNYEQH----RKESED-AVKALAKEKDLLEREKWELRRQ 117
++M E E+L+ + ++ +K ED VKA +++ ++ + E +
Sbjct: 899 TKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKEL 958
Query: 118 AKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDV 160
++ +D L +++ N+ +EL+A A T +++
Sbjct: 959 ERKLSD----LEKKMETSHNQCQELKARYERATSETKTKHEEI 997
Score = 34.3 bits (77), Expect = 0.16
Identities = 31/140 (22%), Positives = 61/140 (43%)
Query: 24 TELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFI 83
TE + A+K +EAL+ + ++L E+ +++ + + + E++L
Sbjct: 337 TETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALAR 396
Query: 84 RNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELE 143
++QH E E + L + +REK EL Q +E L+ +++ + +LE
Sbjct: 397 DGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLE 456
Query: 144 AELAMAKQSLATLTKDVPKR 163
K + L KD+ R
Sbjct: 457 VATVSEKSRIMELEKDLALR 476
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 53.9 bits (128), Expect = 2e-07
Identities = 40/171 (23%), Positives = 79/171 (46%), Gaps = 15/171 (8%)
Query: 5 LAKDLEESQGGKSSEVLSATELRV-QLAQKEQELARAKEAL----QAMKADRKRLKGEKT 59
+ K+ E S+ + L EL++ L + E+++ KE L Q +K E
Sbjct: 798 IEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAV 857
Query: 60 DLVSQMQQLYATLESREEQ----------LRDFIRNYEQHRKESEDAVKALAKEKDLLER 109
+ MQ+ L +EEQ LR+ + + E +E ++ + L K K+ LE
Sbjct: 858 SVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLEN 917
Query: 110 EKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDV 160
+ E+ + + + + T + +L LK+ ++EL+ +L A ++ + L K +
Sbjct: 918 DIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSI 968
Score = 39.7 bits (91), Expect = 0.004
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 18/148 (12%)
Query: 22 SATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQM-------QQLYATLES 74
S ++ V+ Q +QE A+ E ++K L+ + +DL +M Q+L A E
Sbjct: 967 SIEDMTVKAEQSQQEAAKKHEE------EKKELERKLSDLEKKMETSHNQCQELKARYER 1020
Query: 75 REEQLR----DFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRS 130
+ + + ++N ++ ++ED +K +E L +E ELR+QA +A TA
Sbjct: 1021 ATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTA-ED 1079
Query: 131 QLDLKDNRMKELEAELAMAKQSLATLTK 158
+ + + KE LA + + T K
Sbjct: 1080 AMQIMEQMTKEKTETLASLEDTKQTNAK 1107
Score = 38.1 bits (87), Expect = 0.011
Identities = 39/157 (24%), Positives = 75/157 (47%), Gaps = 9/157 (5%)
Query: 7 KDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQ 66
+D E + K E L A ++V + +KE L + L KA+ + L E D ++++Q
Sbjct: 670 QDSERAAHAKEMEALRAKLMKV-IKEKENSLEAIRSKLD--KAEDQHLV-EMEDTLNKLQ 725
Query: 67 QLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHAT 126
+ A ++ +E ++ N EQ + + A E+ LL+ + LR+ + E
Sbjct: 726 E--AEIKVKELEVLQAKCN-EQTKVIDNFTSQLKATEEKLLDLDA--LRKASSEGKSEMK 780
Query: 127 ALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKR 163
LR QL+ + ++K LE E +++T+++ R
Sbjct: 781 KLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGR 817
Score = 37.4 bits (85), Expect = 0.018
Identities = 36/163 (22%), Positives = 79/163 (48%), Gaps = 15/163 (9%)
Query: 4 MLAKDLEESQGGKSSEVLSATELRV-QLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
ML+ DLE K E L+ E + + ++E++L +AKE L+ A+ ++ G+ + +
Sbjct: 879 MLSSDLE-----KLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQL 933
Query: 63 SQMQQLYATLESREEQLRDFIRNYEQH----RKESED-AVKALAKEKDLLEREKWELRRQ 117
++M E E+L+ + ++ +K ED VKA +++ ++ + E +
Sbjct: 934 TKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKEL 993
Query: 118 AKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDV 160
++ +D L +++ N+ +EL+A A T +++
Sbjct: 994 ERKLSD----LEKKMETSHNQCQELKARYERATSETKTKHEEI 1032
Score = 34.7 bits (78), Expect = 0.12
Identities = 30/137 (21%), Positives = 60/137 (43%), Gaps = 6/137 (4%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMK--ADRKRLKGEKTD 60
+ L ++LE+++ SE EL LA + QE+A + L++ K D +
Sbjct: 481 DKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQE 540
Query: 61 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLERE----KWELRR 116
+ S ++L T + ++ ++ + + +KAL + L +E K +L
Sbjct: 541 ISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEH 600
Query: 117 QAKEATDHATALRSQLD 133
KE +D +S+L+
Sbjct: 601 ANKENSDVIALWKSKLE 617
Score = 32.0 bits (71), Expect = 0.77
Identities = 34/151 (22%), Positives = 63/151 (41%), Gaps = 14/151 (9%)
Query: 24 TELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFI 83
TE + A+K +EAL+ + ++L E+ +++ + + + E++L
Sbjct: 337 TETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALAR 396
Query: 84 RNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALR-------------- 129
++QH E E + L + +REK EL Q +E L+
Sbjct: 397 DGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLE 456
Query: 130 SQLDLKDNRMKELEAELAMAKQSLATLTKDV 160
+Q L+ R+KELE L K L +++
Sbjct: 457 TQTKLEHARIKELEQSLLFEKTKADKLQREL 487
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 53.5 bits (127), Expect = 2e-07
Identities = 45/161 (27%), Positives = 72/161 (44%), Gaps = 17/161 (10%)
Query: 16 KSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG-------EKTDLVSQMQQL 68
K +L + E ++A ++E R KE L+ +A RK L+ EK DL Q+Q
Sbjct: 837 KIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAE 896
Query: 69 YATLESREEQLRDFIRNYEQ---------HRKESEDAVKA-LAKEKDLLEREKWELRRQA 118
L EE+ I+N Q R E E+ + A L +K LE E EL++
Sbjct: 897 QDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDI 956
Query: 119 KEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
+ + + +N++K L E+A + +A LTK+
Sbjct: 957 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKE 997
Score = 43.9 bits (102), Expect = 2e-04
Identities = 31/141 (21%), Positives = 71/141 (50%), Gaps = 7/141 (4%)
Query: 25 ELRVQLAQKEQELARAKEALQA----MKADRKRLKGEKTDLVSQMQQLYATLESREEQLR 80
E + +LAQ+ Q+ A EA+ A ++ + RL+ E DL+ +++ A + +++ R
Sbjct: 1390 EAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR 1449
Query: 81 DF---IRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
+F + ++Q +ES+ +++ KE L E ++L+ +E+ +H + +
Sbjct: 1450 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQE 1509
Query: 138 RMKELEAELAMAKQSLATLTK 158
+ +L +L +++ L K
Sbjct: 1510 EISDLTEQLGEGGKNVHELEK 1530
Score = 41.6 bits (96), Expect = 0.001
Identities = 55/257 (21%), Positives = 102/257 (39%), Gaps = 18/257 (7%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKA----DRKRLKGEK 58
+ + +DLEE+ +A LR + A EL + LQ +K ++ K E
Sbjct: 1174 QKMRRDLEEAT---LQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1230
Query: 59 TDLVSQMQQLY---ATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELR 115
D+ S M+Q+ A LE L D Y +E++ ++ ++ L+ E EL
Sbjct: 1231 DDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELA 1290
Query: 116 RQAKEATDHATALRSQLDLKDNRMKELEAEL---AMAKQSLATLTKDVPKRHSLAMPGET 172
RQ +E + L +M++L+ +L AK +LA + RH + E
Sbjct: 1291 RQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSA--RHDCDLLREQ 1348
Query: 173 VLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAA 232
+E +A+L + S+ + + A ++ + + + DA A
Sbjct: 1349 Y---EEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEA 1405
Query: 233 EGDRSSTPSDINSPRHR 249
++ S + +HR
Sbjct: 1406 VEAVNAKCSSLEKTKHR 1422
Score = 39.7 bits (91), Expect = 0.004
Identities = 38/148 (25%), Positives = 72/148 (48%), Gaps = 10/148 (6%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAK-EALQAMKADRKRLKGEKTDL 61
E L + LEE GK+ L+ +Q A+ + +L R + E KA+ +R+ +
Sbjct: 1315 EDLKRQLEEE--GKAKNALAHA---LQSARHDCDLLREQYEEETEAKAELQRVLSKANSE 1369
Query: 62 VSQMQQLYAT-LESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
V+Q + Y T R E+L + + Q +++E+AV+A+ + LE+ K L+ + ++
Sbjct: 1370 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIED 1429
Query: 121 A---TDHATALRSQLDLKDNRMKELEAE 145
+ + A + LD K ++ AE
Sbjct: 1430 LMVDVERSNAAAAALDKKQRNFDKILAE 1457
Score = 33.1 bits (74), Expect = 0.35
Identities = 26/132 (19%), Positives = 56/132 (42%), Gaps = 7/132 (5%)
Query: 27 RVQLAQKEQELARAKEALQAMKAD----RKRLKGEKTDLVSQMQQLYATL---ESREEQL 79
++QL K +E+ E + M A+ +++L+ E ++L + L TL E +
Sbjct: 914 KIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT 973
Query: 80 RDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRM 139
+ ++N + ++ + L KEK L+ + + D +L + ++
Sbjct: 974 ENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQV 1033
Query: 140 KELEAELAMAKQ 151
+LE L K+
Sbjct: 1034 DDLEGSLEQEKK 1045
Score = 32.3 bits (72), Expect = 0.59
Identities = 30/163 (18%), Positives = 79/163 (48%), Gaps = 16/163 (9%)
Query: 4 MLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVS 63
M+A++L++ Q + + + + L A++ A+K +K+L+ L +
Sbjct: 1766 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQI--ALKGGKKQLQ----KLEA 1819
Query: 64 QMQQLYATLESREEQLRDFIRNYEQHRK-------ESEDAVKALAKEKDLLEREKWEL-- 114
++++L LE+ +++ + ++ + + ++E+ K L + +DL+++ + ++
Sbjct: 1820 RVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKA 1879
Query: 115 -RRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATL 156
+RQA+EA + A S+ + + E E +A+ + L
Sbjct: 1880 YKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKL 1922
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 53.5 bits (127), Expect = 2e-07
Identities = 49/187 (26%), Positives = 87/187 (46%), Gaps = 36/187 (19%)
Query: 29 QLAQKEQELARAKEA--------------------------------LQAMKADRKRLKG 56
Q+A+KE+EL+R KE + ++A+ +RL+
Sbjct: 1335 QIARKEEELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQR 1394
Query: 57 EKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRR 116
+T+L Q+++L ++R E R+ R Q R + + +A A+EK + +K L++
Sbjct: 1395 RRTELERQLEELERERQARREAEREVQR--LQQRLAALEQEEAEAREK-VTHTQKVVLQQ 1451
Query: 117 QAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNG 176
++A +HA LR QL+ + +R + LE EL ++ LA L K K + V G
Sbjct: 1452 DPQQAREHA-LLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKG 1510
Query: 177 NQEWVVQ 183
+ E +Q
Sbjct: 1511 DTEQEIQ 1517
Score = 35.0 bits (79), Expect = 0.091
Identities = 42/159 (26%), Positives = 74/159 (46%), Gaps = 12/159 (7%)
Query: 1 MKEMLAKDLEESQGGKSSEVLSATE-LRVQLAQKEQELARAKEALQAMKADRKRLKGEKT 59
+KE+L + + +Q + ++ E LR Q +E E+ ++ + A+ ++ R + + T
Sbjct: 994 VKEVLRIEPDRAQADEVLQLREELEALRRQKGAREAEVLLLQQRVAALAEEKSRAQEKVT 1053
Query: 60 DLVSQMQQLYATLESREEQLRDFIRNYEQHRKESE-------DAVKALAKEKDLLEREKW 112
+ Q LE+ +QL++ + +Q R++ E D +K L KE+ + E K
Sbjct: 1054 EKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAE-GKI 1112
Query: 113 ELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQ 151
++ K D AT R DL R E EA A A Q
Sbjct: 1113 TVKEVLKVEKDAATE-REVSDL--TRQYEDEAAKARASQ 1148
Score = 32.0 bits (71), Expect = 0.77
Identities = 33/162 (20%), Positives = 70/162 (43%), Gaps = 16/162 (9%)
Query: 1 MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
++++ A + Q K E L A +LR L + + + + +++ ++K E+
Sbjct: 784 VQKICANSQQYQQAVKDYE-LEAEKLRSLLDLENGRSSHVSKRAR-LQSPATKVKEEEAA 841
Query: 61 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
L ++ ++YA R + L +F N + + E E + L R +
Sbjct: 842 LAAKFTEVYAINRQRLQNL-EFALNLLRQQPEVEVTHETLQ-------------RNRPDS 887
Query: 121 ATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPK 162
+ A +R +LD + R ++LE E+ ++ + TL P+
Sbjct: 888 GVEEAWKIRKELDEETERRRQLENEVKSTQEEIWTLRNQGPQ 929
Score = 29.6 bits (65), Expect = 3.8
Identities = 39/163 (23%), Positives = 66/163 (40%), Gaps = 24/163 (14%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
E ++LE + + L+ +LA EQE A A+E K +K L
Sbjct: 1400 ERQLEELERERQARREAEREVQRLQQRLAALEQEEAEARE---------KVTHTQKVVLQ 1450
Query: 63 SQMQQLYATLESREEQLRDFIRNYEQHRKE-SEDAVKALAKEKDLLE----REKWELRRQ 117
QQ +RE L EQHR++ E ++ L ++ LE +EK L
Sbjct: 1451 QDPQQ------AREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSES 1504
Query: 118 AK----EATDHATALRSQLDLKDNRMKELEAELAMAKQSLATL 156
+ + L+S L+ + +EL+ E++ + L+ L
Sbjct: 1505 VQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSEL 1547
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 52.4 bits (124), Expect = 6e-07
Identities = 63/308 (20%), Positives = 127/308 (41%), Gaps = 63/308 (20%)
Query: 22 SATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRD 81
+A L VQ+ + ++ A + L+A K +++ E V+++++L L+ ++QL+
Sbjct: 1081 NAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQK 1140
Query: 82 FIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKE 141
++ E +K+ A++ L+ E + R KE L +L K+N++++
Sbjct: 1141 TMQELELVKKD--------AQQTTLMNMEIADYERLMKE-------LNQKLTNKNNKIED 1185
Query: 142 LEAELAMAKQSLATLTKDVPKRHS---------------LAMPGETVLNGNQ----EWVV 182
LE E+ + KQ TL +++ S L + + + Q ++
Sbjct: 1186 LEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLIL 1245
Query: 183 QADLPLTAAIRQSQQTLY--------------HSHPPHPADRQAVRVSPCHSRQPSVISD 228
QA L Q Q +Y H H A++ +S R ++ +
Sbjct: 1246 QASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEE 1305
Query: 229 ASAAEGDRSSTPSDINSPRHRTH---------SLCNGDSPGPVQKNLHNPIVQSLEDLED 279
AA+ ++++ S+ S + R H S+ ++ G Q+ H LE L D
Sbjct: 1306 CRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAKQEREH------LEMLID 1359
Query: 280 QKRKKKKE 287
Q + K ++
Sbjct: 1360 QLKIKLQD 1367
Score = 36.2 bits (82), Expect = 0.041
Identities = 34/162 (20%), Positives = 72/162 (44%), Gaps = 12/162 (7%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
E L K+ +E + + L A + + +L +E KE L+++++++ +L DL+
Sbjct: 954 ENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLI 1013
Query: 63 ---SQMQQLYATLESREEQL---RDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRR 116
+ L E + EQL ++ N+E ++ ++ + + + + +L
Sbjct: 1014 QGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLA 1073
Query: 117 QAKEATDHATALRSQLDLKDNRM-----KELEAELAMAKQSL 153
+ + +A L Q+ L+ R KELEAE +Q +
Sbjct: 1074 RIETLQSNAKLLEVQI-LEVQRAKAMVDKELEAEKLQKEQKI 1114
Score = 33.1 bits (74), Expect = 0.35
Identities = 37/178 (20%), Positives = 76/178 (42%), Gaps = 22/178 (12%)
Query: 4 MLAKDLEESQGGKSSEVLSATEL--RVQLAQKE-------------------QELARAKE 42
+L L +S K+ + S EL +++ +KE +EL +++
Sbjct: 927 LLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRK 986
Query: 43 ALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAK 102
Q +K + + L+ EK L + M+ L ES + L ++ + EQ E E A +
Sbjct: 987 ETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHR 1046
Query: 103 EKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDV 160
+D L R+ Q + L ++++ + K LE ++ +++ A + K++
Sbjct: 1047 IED-LTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKEL 1103
Score = 32.3 bits (72), Expect = 0.59
Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 25/169 (14%)
Query: 16 KSSEVLSATELRVQLAQKEQ----------ELARAKEALQA----MKADRKRLKGEKTDL 61
+ V+ EL+ L EQ E+ KEALQ+ MK ++ + E +L
Sbjct: 819 QEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNL 878
Query: 62 VSQMQQLYATLESRE---EQLRDFIRNYEQ-----HRKESEDAVKALAKEKDLLERE--- 110
+ Q++++ T E E+ + FI+ +E +KE D L KD L +
Sbjct: 879 LIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSV 938
Query: 111 KWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
K + KE + L + K+ ++ +++ AK+ L + K+
Sbjct: 939 KNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKE 987
Score = 29.3 bits (64), Expect = 5.0
Identities = 22/90 (24%), Positives = 40/90 (44%), Gaps = 12/90 (13%)
Query: 44 LQAMKADRKRLKGEKTDLVSQMQQLYATLESRE-----------EQLRDFIRNYEQHRKE 92
LQA+ ++ EK +L Q + LE E+L+ +R+YEQ +
Sbjct: 783 LQAVGESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVL 842
Query: 93 SEDAVKALAKEKDLLEREKWELRRQAKEAT 122
++ + EK+ L+ + E+ + A E T
Sbjct: 843 LRKELEEIQSEKEALQSDLLEM-KNANEKT 871
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal
[Homo sapiens]
Length = 1937
Score = 51.6 bits (122), Expect = 9e-07
Identities = 42/161 (26%), Positives = 73/161 (45%), Gaps = 17/161 (10%)
Query: 16 KSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG-------EKTDLVSQMQQL 68
K +L + E ++A ++E + K+ L +A RK L+ EK DL Q+Q
Sbjct: 838 KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSE 897
Query: 69 YATLESREEQLRDFIRNYEQ---------HRKESEDAVKA-LAKEKDLLEREKWELRRQA 118
+L EE+ I+N Q R E E+ + A L +K LE E EL++
Sbjct: 898 ADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDI 957
Query: 119 KEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
+ + + +N++K L E+A +++A L+K+
Sbjct: 958 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKE 998
Score = 43.9 bits (102), Expect = 2e-04
Identities = 32/141 (22%), Positives = 71/141 (50%), Gaps = 7/141 (4%)
Query: 25 ELRVQLAQKEQELARAKEALQA----MKADRKRLKGEKTDLVSQMQQLYATLESREEQLR 80
E + +LAQ+ QE EA+ A ++ ++RL+ E DL+ +++ A + +++ R
Sbjct: 1391 EAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQR 1450
Query: 81 DF---IRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
+F + ++Q +E++ ++A KE L E ++++ +E+ D LR +
Sbjct: 1451 NFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQ 1510
Query: 138 RMKELEAELAMAKQSLATLTK 158
+ +L ++A + + L K
Sbjct: 1511 EISDLTEQIAEGGKQIHELEK 1531
Score = 38.9 bits (89), Expect = 0.006
Identities = 42/188 (22%), Positives = 84/188 (44%), Gaps = 39/188 (20%)
Query: 2 KEMLAKDLEESQGGKS---SEVLSATELRVQLAQKEQEL-ARAKEA---LQAMKADRKRL 54
K+ L + LE+ + S S++ + +QL +K +EL AR +E ++A +A R +
Sbjct: 1076 KQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKA 1135
Query: 55 KGEKTDLVSQMQQLYATLES--------------REEQLRDFIRNYEQHRKESEDAVKAL 100
+ +++DL +++++ LE RE + + R+ E+ + E V AL
Sbjct: 1136 EKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAAL 1195
Query: 101 AKE------------------KDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKEL 142
K+ K LE+EK EL+ + + + +A A+ + + L
Sbjct: 1196 RKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSL 1255
Query: 143 EAELAMAK 150
E +++ K
Sbjct: 1256 EDQVSELK 1263
Score = 34.7 bits (78), Expect = 0.12
Identities = 44/193 (22%), Positives = 86/193 (44%), Gaps = 13/193 (6%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
K L DL+ +Q +L +L +KE E++ ++ +A +L+ + +L
Sbjct: 1055 KRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKEL 1114
Query: 62 VSQMQQLYATLESR-------EEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWE- 113
+++++L +E+ E+Q D R E+ + E+A A + + +L ++ + E
Sbjct: 1115 QARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEF 1174
Query: 114 --LRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGE 171
LRR +EAT A+ + L K + AEL +L + + + K S
Sbjct: 1175 QKLRRDLEEATLQHEAMVAALRKKH---ADSMAELGEQIDNLQRVKQKLEKEKSELKMET 1231
Query: 172 TVLNGNQEWVVQA 184
L+ N E + +A
Sbjct: 1232 DDLSSNAEAISKA 1244
Score = 34.3 bits (77), Expect = 0.16
Identities = 41/176 (23%), Positives = 80/176 (45%), Gaps = 21/176 (11%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAK-EALQAMKADRKRLKGEKTDL 61
E L LEE K+ A +Q ++ + +L R + E Q KA+ +R +
Sbjct: 1316 EELKHQLEEETKAKN-----ALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSE 1370
Query: 62 VSQMQQLYAT-LESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
V+Q + Y T R E+L + + Q +E+E+ V+A+ + LE+ K L+ + ++
Sbjct: 1371 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVED 1430
Query: 121 A---TDHATALRSQLDLKD-----------NRMKELEAELAMAKQSLATLTKDVPK 162
+ + A + LD K + +E +AEL +++ +L+ ++ K
Sbjct: 1431 LMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFK 1486
Score = 34.3 bits (77), Expect = 0.16
Identities = 34/164 (20%), Positives = 79/164 (48%), Gaps = 18/164 (10%)
Query: 4 MLAKDLEESQGG-------KSSEVLSATELRVQLAQKEQ-ELARAKEALQAMKADRKRLK 55
M+A++L++ Q K + + +L+ +L + EQ L K+ +Q ++A + L+
Sbjct: 1767 MMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELE 1826
Query: 56 GEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWEL- 114
GE + + + L E ++++ E+ RK + + +DL+++ + ++
Sbjct: 1827 GEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKN-------VLRLQDLVDKLQAKVK 1879
Query: 115 --RRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATL 156
+RQA+EA + + A S+ + ++E E +A+ + L
Sbjct: 1880 SYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKL 1923
Score = 33.1 bits (74), Expect = 0.35
Identities = 25/132 (18%), Positives = 56/132 (42%), Gaps = 7/132 (5%)
Query: 27 RVQLAQKEQELARAKEALQAMKAD----RKRLKGEKTDLVSQMQQLYATL---ESREEQL 79
++QL K +E+ E + + A+ +++L+ E ++L + L TL E +
Sbjct: 915 KIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT 974
Query: 80 RDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRM 139
+ ++N + ++ + L+KEK L+ + + D L + ++
Sbjct: 975 ENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQV 1034
Query: 140 KELEAELAMAKQ 151
+LE L K+
Sbjct: 1035 DDLEGSLEQEKK 1046
Score = 33.1 bits (74), Expect = 0.35
Identities = 32/179 (17%), Positives = 70/179 (39%), Gaps = 14/179 (7%)
Query: 1 MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
M L K +S ++ + ++ +L +++ EL + L + + KG
Sbjct: 1191 MVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEK 1250
Query: 61 LVSQMQQLYATLESREEQLRDFIRN--------------YEQHRKESEDAVKALAKEKDL 106
+ ++ + L+++EE+ + I + Y + E + V L++ K
Sbjct: 1251 MCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQA 1310
Query: 107 LEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHS 165
++ EL+ Q +E T AL L + L + ++ A L + + K +S
Sbjct: 1311 STQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS 1369
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 51.2 bits (121), Expect = 1e-06
Identities = 43/161 (26%), Positives = 72/161 (44%), Gaps = 17/161 (10%)
Query: 16 KSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG-------EKTDLVSQMQQL 68
K +L + E ++A ++E + KE L +A RK L+ EK DL Q+Q
Sbjct: 839 KIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898
Query: 69 YATLESREEQLRDFIRNYEQ---------HRKESEDAVKA-LAKEKDLLEREKWELRRQA 118
+L EE+ I+ Q R E E+ + A L +K LE E EL++
Sbjct: 899 ADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 958
Query: 119 KEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
+ + + +N++K L E+A +++A LTK+
Sbjct: 959 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKE 999
Score = 42.0 bits (97), Expect = 7e-04
Identities = 39/184 (21%), Positives = 87/184 (47%), Gaps = 25/184 (13%)
Query: 25 ELRVQLAQKEQELARAKEALQA----MKADRKRLKGEKTDLVSQMQQLYATLESREEQLR 80
E + +LAQ+ Q+ EA+ A ++ ++RL+ E DL+ +++ A + +++ R
Sbjct: 1392 EAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQR 1451
Query: 81 DF---IRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
+F + ++Q +E+ ++A KE L E ++++ +E+ D QL+
Sbjct: 1452 NFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLD-------QLETLKR 1504
Query: 138 RMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQ 197
K L+ E++ + +A K + + + ++ V Q L AA+ +++
Sbjct: 1505 ENKNLQQEISDLTEQIAEGGKRIHELEKI-----------KKQVEQEKSELQAALEEAEA 1553
Query: 198 TLYH 201
+L H
Sbjct: 1554 SLEH 1557
Score = 40.0 bits (92), Expect = 0.003
Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 29/166 (17%)
Query: 7 KDLEESQGGKSSEVLSATELRVQLAQKEQELA----RAKEALQAMKADRKRLKGEKTDLV 62
K E G S++ L +QL +K +EL +E ++A +A R + + +++DL
Sbjct: 1085 KKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS 1144
Query: 63 SQMQQLYATLES--------------REEQLRDFIRNYE----QH-------RKESEDAV 97
+++++ LE RE + + R+ E QH RK+ D+V
Sbjct: 1145 RELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSV 1204
Query: 98 KALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELE 143
L ++ D L+R K +L ++ E L S ++ LE
Sbjct: 1205 AELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLE 1250
Score = 36.2 bits (82), Expect = 0.041
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 10/148 (6%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAK-EALQAMKADRKRLKGEKTDL 61
E L + LEE KS A +Q ++ + +L R + E Q KA+ +R +
Sbjct: 1317 EELKRQLEEEIKAKS-----ALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSE 1371
Query: 62 VSQMQQLYAT-LESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
V+Q + Y T R E+L + + Q +++E+ V+A+ + LE+ K L+ + ++
Sbjct: 1372 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVED 1431
Query: 121 A---TDHATALRSQLDLKDNRMKELEAE 145
+ A + LD K ++ AE
Sbjct: 1432 LMIDVERTNAACAALDKKQRNFDKILAE 1459
Score = 33.9 bits (76), Expect = 0.20
Identities = 36/158 (22%), Positives = 73/158 (46%), Gaps = 15/158 (9%)
Query: 8 DLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQ 67
+LE SQ K S LS +++ A +E + + L+ +K + K L+ E +DL Q+
Sbjct: 1470 ELEASQ--KESRSLSTELFKIKNAYEE-----SLDQLETLKRENKNLQQEISDLTEQI-- 1520
Query: 68 LYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATA 127
A R +L + EQ + E + AL + + LE E+ ++ R E +
Sbjct: 1521 --AEGGKRIHELEKIKKQVEQEKSELQ---AALEEAEASLEHEEGKILRIQLELNQVKSE 1575
Query: 128 LRSQLDLKDNRMKELEA-ELAMAKQSLATLTKDVPKRH 164
+ ++ KD + +++ + + + +TL ++ R+
Sbjct: 1576 VDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRN 1613
Score = 33.1 bits (74), Expect = 0.35
Identities = 39/184 (21%), Positives = 79/184 (42%), Gaps = 25/184 (13%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
K L DL+ +Q +L +L +KE E++ + ++ +A +L+ + +L
Sbjct: 1056 KRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKEL 1115
Query: 62 VSQMQQLYATLESR-------EEQLRDFIRNYEQHRKESEDAVKALAKEKDL---LEREK 111
+++++L +E+ E+Q D R E+ + E+A A + + ++ E E
Sbjct: 1116 QARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEF 1175
Query: 112 WELRRQAKEAT---------------DHATALRSQLDLKDNRMKELEAELAMAKQSLATL 156
++RR +EAT D L Q+D ++LE E + K + L
Sbjct: 1176 QKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDL 1235
Query: 157 TKDV 160
++
Sbjct: 1236 ASNM 1239
Score = 32.3 bits (72), Expect = 0.59
Identities = 28/136 (20%), Positives = 59/136 (43%), Gaps = 5/136 (3%)
Query: 21 LSATELRVQLAQKE-QELARAKEALQA-MKADRKRLKGEKTDLVSQMQQLYATL---ESR 75
L T+++++ KE E A +E + A + A +++L+ E ++L + L TL E
Sbjct: 912 LIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE 971
Query: 76 EEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLK 135
+ + ++N + ++ + L KEK L+ + + D L
Sbjct: 972 KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKL 1031
Query: 136 DNRMKELEAELAMAKQ 151
+ ++ +LE L K+
Sbjct: 1032 EQQVDDLEGSLEQEKK 1047
Score = 31.6 bits (70), Expect = 1.0
Identities = 37/197 (18%), Positives = 79/197 (40%), Gaps = 36/197 (18%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELR------VQLAQKEQELARAKEALQAMKADRK---- 52
+ + +DLEE+ E +AT + +L ++ L R K+ L+ K++ K
Sbjct: 1176 QKMRRDLEEAT--LQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1233
Query: 53 ----------RLKGEKTDLVSQMQQLYATLESREEQLRDFIRN--------------YEQ 88
+ KG + ++ + ++++EE+ + I + Y +
Sbjct: 1234 DLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSR 1293
Query: 89 HRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAM 148
E + V L++ K ++ EL+RQ +E +AL L + L +
Sbjct: 1294 QLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEE 1353
Query: 149 AKQSLATLTKDVPKRHS 165
+++ A L + + K +S
Sbjct: 1354 EQEAKAELQRAMSKANS 1370
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 50.8 bits (120), Expect = 2e-06
Identities = 40/165 (24%), Positives = 81/165 (49%), Gaps = 9/165 (5%)
Query: 7 KDLEESQGGKSSEVLSATE-LRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL---V 62
KD+ E + K + + E L+ QL K+++L K+ +++++ D L +
Sbjct: 531 KDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEAL 590
Query: 63 SQMQQLYATL-ESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEA 121
S+ +++ L E RE R+ + E RKE++D L ++ + L+ E E +
Sbjct: 591 SEKERIIERLKEQRERDDRERLEEIESFRKENKD----LKEKVNALQAELTEKESSLIDL 646
Query: 122 TDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSL 166
+HA++L S +D+++K LE + K+ + L + K H++
Sbjct: 647 KEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNI 691
Score = 43.1 bits (100), Expect = 3e-04
Identities = 40/171 (23%), Positives = 82/171 (47%), Gaps = 23/171 (13%)
Query: 26 LRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQ-------LYATLESREEQ 78
LR++L +KE L + + LQ + ++ L GE D+ ++ L +E+ +EQ
Sbjct: 495 LRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQ 554
Query: 79 LRDF----------IRNYEQHRKESEDAV----KALAKEKDLLEREKWELRRQAKEATDH 124
LRD +++ + ++ A+ +AL++++ ++ER K + R +E +
Sbjct: 555 LRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEE 614
Query: 125 ATALRSQ-LDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVL 174
+ R + DLK+ ++ L+AEL + SL L + S + ++ L
Sbjct: 615 IESFRKENKDLKE-KVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKL 664
Score = 29.6 bits (65), Expect = 3.8
Identities = 39/173 (22%), Positives = 77/173 (44%), Gaps = 22/173 (12%)
Query: 9 LEESQGGKSSE--VLSATELRVQLAQKE-----QELARAKEALQAMKADRKRLKGEKTDL 61
L++ G + +E + TE + Q E +EL ++ L+ M+ + K
Sbjct: 242 LQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNAR 301
Query: 62 VSQMQQLYATLESREEQLRDFIRNYEQHRK--ESEDAVKALA-----KEKDLLE-REKWE 113
+++L L+S+ + + E+ R+ E+E V L KEK+ + RE+
Sbjct: 302 DESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELH 361
Query: 114 LRRQAKEATDHATALRSQLDLKDNR-------MKELEAELAMAKQSLATLTKD 159
R Q + AL++ +++KD + +++LE E+ M K + T+D
Sbjct: 362 RRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTED 414
Score = 29.3 bits (64), Expect = 5.0
Identities = 25/121 (20%), Positives = 50/121 (41%), Gaps = 2/121 (1%)
Query: 26 LRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDF--I 83
L+ +L +KE L KE ++ + + + L ++Q E QL+ I
Sbjct: 632 LQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNI 691
Query: 84 RNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELE 143
+ + E D +K L KE E + + + + + ++ + KD ++ ELE
Sbjct: 692 EDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELE 751
Query: 144 A 144
+
Sbjct: 752 S 752
>gi|92091575 coiled-coil domain containing 57 [Homo sapiens]
Length = 915
Score = 50.8 bits (120), Expect = 2e-06
Identities = 53/212 (25%), Positives = 90/212 (42%), Gaps = 26/212 (12%)
Query: 13 QGGKSSEVLSATELRVQLAQKEQEL-----ARAKEALQAMKADRKRLKGEKTDLVSQMQQ 67
Q S + EL+V+L KE E A+A E+LQ +A L+ + ++Q
Sbjct: 192 QADNMSNTALSRELKVKLLHKELEALKEAGAKAAESLQRAEATNAELERKLQSRAGELQD 251
Query: 68 LYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREK---------------W 112
L A +R + L D + + + RK+ E+ K +E D L REK
Sbjct: 252 LEAMSRARVKDLEDKLHSVQLTRKKEEETFKRKHEELDRLAREKDAVLVAVKGAHVEQLQ 311
Query: 113 ELRRQAKEATDHATALRSQLDLKDNRM----KELEAELAMAKQSLATLTKDVPKRHSLAM 168
EL+ + E H L +QL + R KE +A + ++ +T+ K +
Sbjct: 312 ELQTRVLELQAHCETLEAQLRRAEWRQADTAKEKDAAIDQLREDASTV-KSAWDAQIAQL 370
Query: 169 PGETVLNGNQ-EWVVQADLPLTAAIRQSQQTL 199
E V Q + + + ++ L A + +SQQ +
Sbjct: 371 SKEMVSRDLQIQTLQEEEVKLKAQVARSQQDI 402
Score = 30.8 bits (68), Expect = 1.7
Identities = 30/133 (22%), Positives = 57/133 (42%), Gaps = 28/133 (21%)
Query: 25 ELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIR 84
E ++L + + A+A+E +A +A+ LK E L + + +E ++Q +
Sbjct: 66 ERDLELERYDAAFAQAREWEEARRAEVSELKIEAAKLRQALAREARKVEELQQQQQ---L 122
Query: 85 NYEQHRKESE----DAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMK 140
+++HR E E D + ++ E KW L R +++
Sbjct: 123 AFQEHRLELERVHSDKNGEIDHHREQYENLKWTLER---------------------KLE 161
Query: 141 ELEAELAMAKQSL 153
EL+ ELA+ +Q L
Sbjct: 162 ELDGELALQRQEL 174
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 50.8 bits (120), Expect = 2e-06
Identities = 43/161 (26%), Positives = 71/161 (44%), Gaps = 17/161 (10%)
Query: 16 KSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG-------EKTDLVSQMQQL 68
K +L + E ++A ++E + KE L +A RK L+ EK DL Q+Q
Sbjct: 839 KIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898
Query: 69 YATLESREEQLRDFIRNYEQ---------HRKESEDAVKA-LAKEKDLLEREKWELRRQA 118
L EE+ I+ Q R E E+ + A L +K LE E EL++
Sbjct: 899 ADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 958
Query: 119 KEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
+ + + +N++K L E+A +++A LTK+
Sbjct: 959 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKE 999
Score = 42.7 bits (99), Expect = 4e-04
Identities = 30/141 (21%), Positives = 72/141 (51%), Gaps = 7/141 (4%)
Query: 25 ELRVQLAQKEQELARAKEALQA----MKADRKRLKGEKTDLVSQMQQLYATLESREEQLR 80
E + +LAQ+ Q+ EA+ + ++ ++RL+ E DL+ +++ A + +++ R
Sbjct: 1392 EAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQR 1451
Query: 81 DF---IRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
+F + ++Q +E++ ++A KE L E ++++ +E+ DH L+ +
Sbjct: 1452 NFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQ 1511
Query: 138 RMKELEAELAMAKQSLATLTK 158
+ +L ++A + + L K
Sbjct: 1512 EISDLTEQIAEGGKHIHELEK 1532
Score = 37.4 bits (85), Expect = 0.018
Identities = 35/175 (20%), Positives = 75/175 (42%), Gaps = 32/175 (18%)
Query: 8 DLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQ 67
++ QG E A +L+ ++ + + + +E ++A +A R + + +++DL ++++
Sbjct: 1090 EMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE 1149
Query: 68 LYATLES--------------REEQLRDFIRNYE----QH-------RKESEDAVKALAK 102
+ LE RE + + R+ E QH RK+ D+V L +
Sbjct: 1150 ISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGE 1209
Query: 103 E-------KDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAK 150
+ K LE+EK EL+ + + + + + + LE +L+ K
Sbjct: 1210 QIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIK 1264
Score = 37.0 bits (84), Expect = 0.024
Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 10/158 (6%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
+ + +DLEES +A LR + A EL ++LQ +K ++L+ EK++L
Sbjct: 1176 QKMRRDLEEST---LQHEATAAALRKKHADSVAELGEQIDSLQRVK---QKLEKEKSELK 1229
Query: 63 SQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEAT 122
++ L + +E+ + N+E+ + ED + + +++ +R EL Q
Sbjct: 1230 MEINDLASNMETVSKAKA----NFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLH 1285
Query: 123 DHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDV 160
+ QLD KD + +L Q + L + +
Sbjct: 1286 TESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQL 1323
Score = 35.4 bits (80), Expect = 0.070
Identities = 37/148 (25%), Positives = 69/148 (46%), Gaps = 10/148 (6%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAK-EALQAMKADRKRLKGEKTDL 61
E L + LEE KS+ + +Q A+ + +L R + E Q KA+ +R +
Sbjct: 1317 EELKRQLEEETKAKSTLAHA-----LQSARHDCDLLREQYEEEQEAKAELQRGMSKANSE 1371
Query: 62 VSQMQQLYAT-LESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
V+Q + Y T R E+L + + Q +++E+ V+A+ + LE+ K L+ + ++
Sbjct: 1372 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVED 1431
Query: 121 A---TDHATALRSQLDLKDNRMKELEAE 145
+ + A LD K ++ AE
Sbjct: 1432 LMIDVERSNAACIALDKKQRNFDKVLAE 1459
Score = 34.7 bits (78), Expect = 0.12
Identities = 34/138 (24%), Positives = 63/138 (45%), Gaps = 8/138 (5%)
Query: 8 DLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQ 67
+LE SQ K S LS +V+ A +E + + L+ +K + K L+ E +DL Q+ +
Sbjct: 1470 ELEASQ--KESRSLSTELFKVKNAYEE-----SLDHLETLKRENKNLQQEISDLTEQIAE 1522
Query: 68 LYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATA 127
+ E+ + + + E+A +L E+ + R + EL + E
Sbjct: 1523 GGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAE 1582
Query: 128 LRSQLD-LKDNRMKELEA 144
+LD LK N ++ +E+
Sbjct: 1583 KDEELDQLKRNHLRVVES 1600
Score = 33.5 bits (75), Expect = 0.26
Identities = 38/184 (20%), Positives = 79/184 (42%), Gaps = 25/184 (13%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
K L DL+ +Q +L +L +KE E++ + ++ +A +L+ + +L
Sbjct: 1056 KRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKEL 1115
Query: 62 VSQMQQLYATLESR-------EEQLRDFIRNYEQHRKESEDAVKALAKEKDL---LEREK 111
+++++L +E+ E+Q D R E+ + E+A A + + ++ E E
Sbjct: 1116 QARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEF 1175
Query: 112 WELRRQAKEAT---------------DHATALRSQLDLKDNRMKELEAELAMAKQSLATL 156
++RR +E+T D L Q+D ++LE E + K + L
Sbjct: 1176 QKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDL 1235
Query: 157 TKDV 160
++
Sbjct: 1236 ASNM 1239
Score = 32.7 bits (73), Expect = 0.45
Identities = 28/136 (20%), Positives = 59/136 (43%), Gaps = 5/136 (3%)
Query: 21 LSATELRVQLAQKE-QELARAKEALQA-MKADRKRLKGEKTDLVSQMQQLYATL---ESR 75
L T+++++ KE E A +E + A + A +++L+ E ++L + L TL E
Sbjct: 912 LIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE 971
Query: 76 EEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLK 135
+ + ++N + ++ + L KEK L+ + + D L
Sbjct: 972 KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKL 1031
Query: 136 DNRMKELEAELAMAKQ 151
+ ++ +LE L K+
Sbjct: 1032 EQQVDDLEGSLEQEKK 1047
Score = 32.3 bits (72), Expect = 0.59
Identities = 41/172 (23%), Positives = 71/172 (41%), Gaps = 20/172 (11%)
Query: 5 LAKDLEESQGGKSSEVLSATELRVQLAQ---KEQELARAKEALQAMKA-------DRKRL 54
LA ++E K++ L QL++ KE+E R L A KA + R
Sbjct: 1235 LASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQ 1294
Query: 55 KGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLERE---- 110
EK +VSQ+ + + E+L+ + + + A+++ + DLL +
Sbjct: 1295 LDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEE 1354
Query: 111 ---KWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
K EL+R +A R++ + + E EL AK+ LA +D
Sbjct: 1355 QEAKAELQRGMSKANSEVAQWRTKYETDAIQRTE---ELEEAKKKLAQRLQD 1403
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 50.4 bits (119), Expect = 2e-06
Identities = 43/175 (24%), Positives = 78/175 (44%), Gaps = 18/175 (10%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKT-- 59
++ L K + +G + EL+ Q+A+ + +LA+ +E LQA A + +K
Sbjct: 1043 RQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMA 1102
Query: 60 -----DLVSQMQQLYATLESR-------EEQLRDFIRNYEQHRKESEDAVKALAKEKDLL 107
+L SQ+ +L LES E+Q RD E + E ED + + A +++L
Sbjct: 1103 LKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELR 1162
Query: 108 EREKWEL----RRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
+ + E+ + +EA H ++ ++EL +L K+ A L K
Sbjct: 1163 SKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEK 1217
Score = 44.3 bits (103), Expect = 2e-04
Identities = 37/166 (22%), Positives = 72/166 (43%), Gaps = 5/166 (3%)
Query: 10 EESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLY 69
EE + KS L + + E+ L R ++ Q ++ R++L+G+ TDL Q+ +L
Sbjct: 1010 EEEEKSKSLAKLK-NKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQ 1068
Query: 70 ATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALR 129
A + + QL E+ + + V+ A +K++ ++ EL Q E + + R
Sbjct: 1069 AQIAELKMQL----AKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Query: 130 SQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLN 175
+ + + + ++L EL K L + L E +N
Sbjct: 1125 ASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVN 1170
Score = 41.2 bits (95), Expect = 0.001
Identities = 40/164 (24%), Positives = 66/164 (40%), Gaps = 14/164 (8%)
Query: 9 LEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKR----LKGEKTDLVSQ 64
L+E ++ A ELR +L K+QEL L+A + + L+ EK +
Sbjct: 885 LQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQN 944
Query: 65 MQQLYATLESREEQLRDF----------IRNYEQHRKESEDAVKALAKEKDLLEREKWEL 114
+Q+L LE E + ++ E+ + ED LAKEK LLE E
Sbjct: 945 IQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEF 1004
Query: 115 RRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
E + + +L + + + +LE L ++ L K
Sbjct: 1005 TTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEK 1048
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/140 (23%), Positives = 68/140 (48%), Gaps = 6/140 (4%)
Query: 2 KEMLAKDLEESQGG-KSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
KE+ K L+E +G KS S T L ++AQ E++L + QA +R + + D
Sbjct: 1788 KELKVK-LQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKD 1846
Query: 61 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
++ Q+ E ++Q +Q +++ E+A +E + +L+R+ ++
Sbjct: 1847 VLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEA----EEEAQRANASRRKLQRELED 1902
Query: 121 ATDHATALRSQLDLKDNRMK 140
AT+ A A+ ++ N+++
Sbjct: 1903 ATETADAMNREVSSLKNKLR 1922
Score = 37.0 bits (84), Expect = 0.024
Identities = 38/181 (20%), Positives = 74/181 (40%), Gaps = 35/181 (19%)
Query: 1 MKEMLAKDLEESQGGKSSEVLSATELRVQLA---QKEQELARAKEALQAMKADRKRLKGE 57
+K LAK EE Q + A + + L + E +++ +E L++ +A R + + +
Sbjct: 1074 LKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQ 1133
Query: 58 KTDLVSQMQQLYATLESR-------------------------EEQLRDFIRNYEQHRKE 92
K DL +++ L LE EE+ + ++ R++
Sbjct: 1134 KRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQK 1193
Query: 93 SEDAVKALAKE-------KDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAE 145
AV+ LA++ K LE+ K L + E + L +++ K++EA+
Sbjct: 1194 HSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQ 1253
Query: 146 L 146
L
Sbjct: 1254 L 1254
Score = 33.5 bits (75), Expect = 0.26
Identities = 37/156 (23%), Positives = 67/156 (42%), Gaps = 24/156 (15%)
Query: 4 MLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVS 63
+L K LEE +++ E+R + +Q +ELA E + +KA+ ++ K
Sbjct: 1171 ILKKTLEEEAKTHEAQI---QEMRQKHSQAVEELAEQLEQTKRVKANLEKAK-------- 1219
Query: 64 QMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATD 123
TLE+ +L + ++ Q + +SE K + + L+ + E R E D
Sbjct: 1220 ------QTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELAD 1273
Query: 124 HATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
T L+ +LD + L+ + + LTKD
Sbjct: 1274 KVTKLQVELD-------NVTGLLSQSDSKSSKLTKD 1302
Score = 32.7 bits (73), Expect = 0.45
Identities = 40/177 (22%), Positives = 71/177 (40%), Gaps = 27/177 (15%)
Query: 1 MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
MK +DL QG +L Q+ + E EL ++ A RK+L+ + D
Sbjct: 1565 MKAQFERDL---QGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKD 1621
Query: 61 L--------------VSQMQQLYATLESREEQLRDFIRNYEQ---HRKESEDAVKA---- 99
L + Q+++L A ++ +L D + E+ KE+E +K+
Sbjct: 1622 LEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAE 1681
Query: 100 ---LAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 153
L +E ER K + +++ E D + L + LEA +A ++ L
Sbjct: 1682 MIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEEL 1738
Score = 32.3 bits (72), Expect = 0.59
Identities = 36/167 (21%), Positives = 71/167 (42%), Gaps = 7/167 (4%)
Query: 11 ESQGGKSSEVLSATELRVQLAQKE-QELARAKEALQAMKADRKRLKGEKTDLVSQMQQLY 69
+S+ K ++ SA E ++Q Q+ QE R K +L K+++ EK Q+++
Sbjct: 1293 DSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKL---KQVEDEKNSFREQLEEEE 1349
Query: 70 ATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALR 129
+ E+Q+ +K+ ED+V L +++ + + +L ++ + A
Sbjct: 1350 EAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYD 1409
Query: 130 SQLDLKDNRMKELE---AELAMAKQSLATLTKDVPKRHSLAMPGETV 173
K +EL+ +L +QS L K K L +T+
Sbjct: 1410 KLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTI 1456
Score = 28.9 bits (63), Expect = 6.5
Identities = 34/180 (18%), Positives = 76/180 (42%), Gaps = 23/180 (12%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
E + LE +G ++EV + + K +++ + LQ + +R++ E D V
Sbjct: 1216 EKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKV 1275
Query: 63 SQMQ---------------------QLYATLESREEQLRDFIRNYEQHRKESEDAVKALA 101
+++Q + ++ LES+ + ++ ++ + + +K +
Sbjct: 1276 TKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVE 1335
Query: 102 KEKDLLEREKWELRRQAKEATDHATA-LRSQLDLKDNRMKELEAELAMAKQSLATLTKDV 160
EK+ RE+ E +AK + A L +Q+ +M++ L A++ L KD+
Sbjct: 1336 DEKNSF-REQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDL 1394
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 50.1 bits (118), Expect = 3e-06
Identities = 38/158 (24%), Positives = 80/158 (50%), Gaps = 9/158 (5%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
+EM AK+ +E Q K + + EL+ +L QK +L K LQ ++L+ E T+L
Sbjct: 852 EEMQAKE-DELQKTKERQQKAENELK-ELEQKHSQLTEEKNLLQ------EQLQAE-TEL 902
Query: 62 VSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEA 121
++ +++ L +++++L + + E +E ED + L E+ + ++ +L Q +E
Sbjct: 903 YAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE 962
Query: 122 TDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
L+ + + ++K+LE E+ + L+K+
Sbjct: 963 EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1000
Score = 46.6 bits (109), Expect = 3e-05
Identities = 41/158 (25%), Positives = 72/158 (45%), Gaps = 8/158 (5%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
KE LA++L S G+++ L ++AQ E+EL + ++AM ++ + L
Sbjct: 1710 KEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL 1769
Query: 62 VSQMQQLYATLESREEQLRDFIRNYEQHRK---ESEDAVKALAKEK-DLLEREKWELRRQ 117
+++ +T + E + R ++ R E E AVK+ K LE + +L Q
Sbjct: 1770 SNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ 1829
Query: 118 AKEATDHATALRSQLDLKDNRMKEL----EAELAMAKQ 151
++ A L KD ++KE+ E E MA+Q
Sbjct: 1830 VEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 1867
Score = 44.7 bits (104), Expect = 1e-04
Identities = 39/176 (22%), Positives = 75/176 (42%), Gaps = 18/176 (10%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKA------------ 49
++ L K + +G S +L+ Q+A+ + +LA+ +E LQA A
Sbjct: 1050 RQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNA 1109
Query: 50 --DRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLL 107
+ L+G +DL + A E+Q RD E + E ED + + A +++L
Sbjct: 1110 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1169
Query: 108 EREKWEL----RRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
+ + E+ + +E H ++ ++EL +L K++ A L K+
Sbjct: 1170 AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKN 1225
Score = 39.7 bits (91), Expect = 0.004
Identities = 37/130 (28%), Positives = 58/130 (44%), Gaps = 11/130 (8%)
Query: 25 ELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL-------VSQMQQLYATLESREE 77
+L+ QL + E EL ++ A +K+L+G+ DL + ++ L +
Sbjct: 1593 QLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQA 1652
Query: 78 QLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
Q++DF R E R S D + A AKE + + Q +E A R Q DL+
Sbjct: 1653 QMKDFQRELEDAR-ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE-- 1709
Query: 138 RMKELEAELA 147
+EL ELA
Sbjct: 1710 -KEELAEELA 1718
Score = 38.9 bits (89), Expect = 0.006
Identities = 40/176 (22%), Positives = 74/176 (42%), Gaps = 25/176 (14%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
+ L L+E K + + L +QL+ +++L ++A++ +KR + E +L
Sbjct: 1345 RNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL 1404
Query: 62 VSQMQQLYATLESRE-------EQLRDFIRNYEQHR-------KESEDAVKALAKEK--- 104
Q ++ A + E ++L D + + + R K+ + LA+EK
Sbjct: 1405 TQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNIS 1464
Query: 105 ----DLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATL 156
D +R + E R + +A A AL L+ K+ ELE M K + L
Sbjct: 1465 SKYADERDRAEAEAREKETKALSLARALEEALEAKE----ELERTNKMLKAEMEDL 1516
Score = 37.7 bits (86), Expect = 0.014
Identities = 34/161 (21%), Positives = 72/161 (44%), Gaps = 9/161 (5%)
Query: 8 DLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQ 67
DLEE E + +L+++ E ++ + ++ + M +L E+ L ++
Sbjct: 954 DLEEQL---EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1010
Query: 68 LYATLESREEQLRDFIRNYEQHR---KESEDAVKALAKEKDLLEREKWELRRQAKEATDH 124
L L EE+ ++ + +H E E +K K + LE+ K +L A + +
Sbjct: 1011 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1070
Query: 125 ATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHS 165
L++Q+ ++ + E EL A LA L ++ ++++
Sbjct: 1071 IADLQAQIAELKMQLAKKEEELQAA---LARLDDEIAQKNN 1108
Score = 36.2 bits (82), Expect = 0.041
Identities = 39/163 (23%), Positives = 77/163 (47%), Gaps = 16/163 (9%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQL-AQKEQ---ELARAKEALQAMKADRKRLKGEK 58
E AK LE ++ +A R Q +KE+ ELA + A++ +++RL+
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1738
Query: 59 TDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQA 118
L ++++ +E+ +++R + EQ +E A + +K+ E + +L RQ
Sbjct: 1739 AQLEEELEEEQGNMEAMSDRVRKATQQAEQ--LSNELATERSTAQKN--ESARQQLERQN 1794
Query: 119 KEATDHATALRSQLDLKDNRMK-ELEAELAMAKQSLATLTKDV 160
KE LRS+L + +K + ++ +A + +A L + V
Sbjct: 1795 KE-------LRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQV 1830
Score = 35.0 bits (79), Expect = 0.091
Identities = 29/140 (20%), Positives = 67/140 (47%), Gaps = 6/140 (4%)
Query: 2 KEMLAKDLEESQGGKSSEVLSA-TELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
KE+ +K L E +G S+ S L ++AQ E+++ + QA K+ + +
Sbjct: 1795 KELRSK-LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1853
Query: 61 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
++ Q++ E +EQ +Q +++ E+A +E + + +L+R+ E
Sbjct: 1854 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEA----EEESQRINANRRKLQRELDE 1909
Query: 121 ATDHATALRSQLDLKDNRMK 140
AT+ A+ +++ ++++
Sbjct: 1910 ATESNEAMGREVNALKSKLR 1929
Score = 33.5 bits (75), Expect = 0.26
Identities = 36/158 (22%), Positives = 76/158 (48%), Gaps = 8/158 (5%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
E L + LE+ + K++ + L + A EL +A Q ++ +K+L+ + +L
Sbjct: 1206 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1265
Query: 63 SQM---QQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWE----LR 115
S+ ++ A L + +L++ + + E+E LAK+ L + + L+
Sbjct: 1266 SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ 1325
Query: 116 RQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 153
+ ++ + +T LR QL+ + N +++ E AKQ+L
Sbjct: 1326 EETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNL 1362
Score = 30.8 bits (68), Expect = 1.7
Identities = 37/187 (19%), Positives = 81/187 (43%), Gaps = 30/187 (16%)
Query: 9 LEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG------------ 56
LEE + K ++V+ A + + + A+ ++ L AMK ++
Sbjct: 778 LEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRL 837
Query: 57 -EKTDLVSQMQQLYATLESREEQL---RDFIRNYEQHRKESEDAVKALAKEKDLL----- 107
K + Q+ + ++++E++L ++ + E KE E L +EK+LL
Sbjct: 838 FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ 897
Query: 108 -------EREKWELRRQAK--EATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
E E+ +R AK E + + ++L+ +++R ++L+AE Q + L +
Sbjct: 898 AETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE 957
Query: 159 DVPKRHS 165
+ + +
Sbjct: 958 QLEEEEA 964
Score = 28.5 bits (62), Expect = 8.5
Identities = 37/177 (20%), Positives = 69/177 (38%), Gaps = 21/177 (11%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
E +L + +EV S T + + K +LA+ +L + D + L E+T
Sbjct: 1272 ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1331
Query: 63 SQMQQLYATLESREEQLRDFI-------RNYEQH-----------RKESED---AVKALA 101
+ LE L+D + +N E+H +K+ +D V+AL
Sbjct: 1332 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1391
Query: 102 KEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
+ K ++E L +Q +E L + + +L +L +Q ++ L K
Sbjct: 1392 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1448
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 50.1 bits (118), Expect = 3e-06
Identities = 38/158 (24%), Positives = 80/158 (50%), Gaps = 9/158 (5%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
+EM AK+ +E Q K + + EL+ +L QK +L K LQ ++L+ E T+L
Sbjct: 859 EEMQAKE-DELQKTKERQQKAENELK-ELEQKHSQLTEEKNLLQ------EQLQAE-TEL 909
Query: 62 VSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEA 121
++ +++ L +++++L + + E +E ED + L E+ + ++ +L Q +E
Sbjct: 910 YAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE 969
Query: 122 TDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
L+ + + ++K+LE E+ + L+K+
Sbjct: 970 EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1007
Score = 46.6 bits (109), Expect = 3e-05
Identities = 41/158 (25%), Positives = 72/158 (45%), Gaps = 8/158 (5%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
KE LA++L S G+++ L ++AQ E+EL + ++AM ++ + L
Sbjct: 1717 KEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL 1776
Query: 62 VSQMQQLYATLESREEQLRDFIRNYEQHRK---ESEDAVKALAKEK-DLLEREKWELRRQ 117
+++ +T + E + R ++ R E E AVK+ K LE + +L Q
Sbjct: 1777 SNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ 1836
Query: 118 AKEATDHATALRSQLDLKDNRMKEL----EAELAMAKQ 151
++ A L KD ++KE+ E E MA+Q
Sbjct: 1837 VEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 1874
Score = 44.7 bits (104), Expect = 1e-04
Identities = 39/176 (22%), Positives = 75/176 (42%), Gaps = 18/176 (10%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKA------------ 49
++ L K + +G S +L+ Q+A+ + +LA+ +E LQA A
Sbjct: 1057 RQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNA 1116
Query: 50 --DRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLL 107
+ L+G +DL + A E+Q RD E + E ED + + A +++L
Sbjct: 1117 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1176
Query: 108 EREKWEL----RRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
+ + E+ + +E H ++ ++EL +L K++ A L K+
Sbjct: 1177 AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKN 1232
Score = 39.7 bits (91), Expect = 0.004
Identities = 37/130 (28%), Positives = 58/130 (44%), Gaps = 11/130 (8%)
Query: 25 ELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL-------VSQMQQLYATLESREE 77
+L+ QL + E EL ++ A +K+L+G+ DL + ++ L +
Sbjct: 1600 QLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQA 1659
Query: 78 QLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
Q++DF R E R S D + A AKE + + Q +E A R Q DL+
Sbjct: 1660 QMKDFQRELEDAR-ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE-- 1716
Query: 138 RMKELEAELA 147
+EL ELA
Sbjct: 1717 -KEELAEELA 1725
Score = 38.9 bits (89), Expect = 0.006
Identities = 40/176 (22%), Positives = 74/176 (42%), Gaps = 25/176 (14%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
+ L L+E K + + L +QL+ +++L ++A++ +KR + E +L
Sbjct: 1352 RNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL 1411
Query: 62 VSQMQQLYATLESRE-------EQLRDFIRNYEQHR-------KESEDAVKALAKEK--- 104
Q ++ A + E ++L D + + + R K+ + LA+EK
Sbjct: 1412 TQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNIS 1471
Query: 105 ----DLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATL 156
D +R + E R + +A A AL L+ K+ ELE M K + L
Sbjct: 1472 SKYADERDRAEAEAREKETKALSLARALEEALEAKE----ELERTNKMLKAEMEDL 1523
Score = 37.7 bits (86), Expect = 0.014
Identities = 34/161 (21%), Positives = 72/161 (44%), Gaps = 9/161 (5%)
Query: 8 DLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQ 67
DLEE E + +L+++ E ++ + ++ + M +L E+ L ++
Sbjct: 961 DLEEQL---EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1017
Query: 68 LYATLESREEQLRDFIRNYEQHR---KESEDAVKALAKEKDLLEREKWELRRQAKEATDH 124
L L EE+ ++ + +H E E +K K + LE+ K +L A + +
Sbjct: 1018 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1077
Query: 125 ATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHS 165
L++Q+ ++ + E EL A LA L ++ ++++
Sbjct: 1078 IADLQAQIAELKMQLAKKEEELQAA---LARLDDEIAQKNN 1115
Score = 36.2 bits (82), Expect = 0.041
Identities = 39/163 (23%), Positives = 77/163 (47%), Gaps = 16/163 (9%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQL-AQKEQ---ELARAKEALQAMKADRKRLKGEK 58
E AK LE ++ +A R Q +KE+ ELA + A++ +++RL+
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1745
Query: 59 TDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQA 118
L ++++ +E+ +++R + EQ +E A + +K+ E + +L RQ
Sbjct: 1746 AQLEEELEEEQGNMEAMSDRVRKATQQAEQ--LSNELATERSTAQKN--ESARQQLERQN 1801
Query: 119 KEATDHATALRSQLDLKDNRMK-ELEAELAMAKQSLATLTKDV 160
KE LRS+L + +K + ++ +A + +A L + V
Sbjct: 1802 KE-------LRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQV 1837
Score = 35.0 bits (79), Expect = 0.091
Identities = 29/140 (20%), Positives = 67/140 (47%), Gaps = 6/140 (4%)
Query: 2 KEMLAKDLEESQGGKSSEVLSA-TELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
KE+ +K L E +G S+ S L ++AQ E+++ + QA K+ + +
Sbjct: 1802 KELRSK-LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1860
Query: 61 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
++ Q++ E +EQ +Q +++ E+A +E + + +L+R+ E
Sbjct: 1861 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEA----EEESQRINANRRKLQRELDE 1916
Query: 121 ATDHATALRSQLDLKDNRMK 140
AT+ A+ +++ ++++
Sbjct: 1917 ATESNEAMGREVNALKSKLR 1936
Score = 33.5 bits (75), Expect = 0.26
Identities = 36/158 (22%), Positives = 76/158 (48%), Gaps = 8/158 (5%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
E L + LE+ + K++ + L + A EL +A Q ++ +K+L+ + +L
Sbjct: 1213 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1272
Query: 63 SQM---QQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWE----LR 115
S+ ++ A L + +L++ + + E+E LAK+ L + + L+
Sbjct: 1273 SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ 1332
Query: 116 RQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 153
+ ++ + +T LR QL+ + N +++ E AKQ+L
Sbjct: 1333 EETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNL 1369
Score = 30.8 bits (68), Expect = 1.7
Identities = 37/187 (19%), Positives = 81/187 (43%), Gaps = 30/187 (16%)
Query: 9 LEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG------------ 56
LEE + K ++V+ A + + + A+ ++ L AMK ++
Sbjct: 785 LEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRL 844
Query: 57 -EKTDLVSQMQQLYATLESREEQL---RDFIRNYEQHRKESEDAVKALAKEKDLL----- 107
K + Q+ + ++++E++L ++ + E KE E L +EK+LL
Sbjct: 845 FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ 904
Query: 108 -------EREKWELRRQAK--EATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
E E+ +R AK E + + ++L+ +++R ++L+AE Q + L +
Sbjct: 905 AETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE 964
Query: 159 DVPKRHS 165
+ + +
Sbjct: 965 QLEEEEA 971
Score = 28.5 bits (62), Expect = 8.5
Identities = 37/177 (20%), Positives = 69/177 (38%), Gaps = 21/177 (11%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
E +L + +EV S T + + K +LA+ +L + D + L E+T
Sbjct: 1279 ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1338
Query: 63 SQMQQLYATLESREEQLRDFI-------RNYEQH-----------RKESED---AVKALA 101
+ LE L+D + +N E+H +K+ +D V+AL
Sbjct: 1339 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1398
Query: 102 KEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
+ K ++E L +Q +E L + + +L +L +Q ++ L K
Sbjct: 1399 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1455
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 50.1 bits (118), Expect = 3e-06
Identities = 38/158 (24%), Positives = 80/158 (50%), Gaps = 9/158 (5%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
+EM AK+ +E Q K + + EL+ +L QK +L K LQ ++L+ E T+L
Sbjct: 859 EEMQAKE-DELQKTKERQQKAENELK-ELEQKHSQLTEEKNLLQ------EQLQAE-TEL 909
Query: 62 VSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEA 121
++ +++ L +++++L + + E +E ED + L E+ + ++ +L Q +E
Sbjct: 910 YAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE 969
Query: 122 TDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
L+ + + ++K+LE E+ + L+K+
Sbjct: 970 EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1007
Score = 46.6 bits (109), Expect = 3e-05
Identities = 41/158 (25%), Positives = 72/158 (45%), Gaps = 8/158 (5%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
KE LA++L S G+++ L ++AQ E+EL + ++AM ++ + L
Sbjct: 1717 KEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL 1776
Query: 62 VSQMQQLYATLESREEQLRDFIRNYEQHRK---ESEDAVKALAKEK-DLLEREKWELRRQ 117
+++ +T + E + R ++ R E E AVK+ K LE + +L Q
Sbjct: 1777 SNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ 1836
Query: 118 AKEATDHATALRSQLDLKDNRMKEL----EAELAMAKQ 151
++ A L KD ++KE+ E E MA+Q
Sbjct: 1837 VEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 1874
Score = 44.7 bits (104), Expect = 1e-04
Identities = 39/176 (22%), Positives = 75/176 (42%), Gaps = 18/176 (10%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKA------------ 49
++ L K + +G S +L+ Q+A+ + +LA+ +E LQA A
Sbjct: 1057 RQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNA 1116
Query: 50 --DRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLL 107
+ L+G +DL + A E+Q RD E + E ED + + A +++L
Sbjct: 1117 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1176
Query: 108 EREKWEL----RRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
+ + E+ + +E H ++ ++EL +L K++ A L K+
Sbjct: 1177 AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKN 1232
Score = 39.7 bits (91), Expect = 0.004
Identities = 37/130 (28%), Positives = 58/130 (44%), Gaps = 11/130 (8%)
Query: 25 ELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL-------VSQMQQLYATLESREE 77
+L+ QL + E EL ++ A +K+L+G+ DL + ++ L +
Sbjct: 1600 QLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQA 1659
Query: 78 QLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
Q++DF R E R S D + A AKE + + Q +E A R Q DL+
Sbjct: 1660 QMKDFQRELEDAR-ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE-- 1716
Query: 138 RMKELEAELA 147
+EL ELA
Sbjct: 1717 -KEELAEELA 1725
Score = 38.9 bits (89), Expect = 0.006
Identities = 40/176 (22%), Positives = 74/176 (42%), Gaps = 25/176 (14%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
+ L L+E K + + L +QL+ +++L ++A++ +KR + E +L
Sbjct: 1352 RNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL 1411
Query: 62 VSQMQQLYATLESRE-------EQLRDFIRNYEQHR-------KESEDAVKALAKEK--- 104
Q ++ A + E ++L D + + + R K+ + LA+EK
Sbjct: 1412 TQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNIS 1471
Query: 105 ----DLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATL 156
D +R + E R + +A A AL L+ K+ ELE M K + L
Sbjct: 1472 SKYADERDRAEAEAREKETKALSLARALEEALEAKE----ELERTNKMLKAEMEDL 1523
Score = 37.7 bits (86), Expect = 0.014
Identities = 34/161 (21%), Positives = 72/161 (44%), Gaps = 9/161 (5%)
Query: 8 DLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQ 67
DLEE E + +L+++ E ++ + ++ + M +L E+ L ++
Sbjct: 961 DLEEQL---EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1017
Query: 68 LYATLESREEQLRDFIRNYEQHR---KESEDAVKALAKEKDLLEREKWELRRQAKEATDH 124
L L EE+ ++ + +H E E +K K + LE+ K +L A + +
Sbjct: 1018 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1077
Query: 125 ATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHS 165
L++Q+ ++ + E EL A LA L ++ ++++
Sbjct: 1078 IADLQAQIAELKMQLAKKEEELQAA---LARLDDEIAQKNN 1115
Score = 36.2 bits (82), Expect = 0.041
Identities = 39/163 (23%), Positives = 77/163 (47%), Gaps = 16/163 (9%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQL-AQKEQ---ELARAKEALQAMKADRKRLKGEK 58
E AK LE ++ +A R Q +KE+ ELA + A++ +++RL+
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1745
Query: 59 TDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQA 118
L ++++ +E+ +++R + EQ +E A + +K+ E + +L RQ
Sbjct: 1746 AQLEEELEEEQGNMEAMSDRVRKATQQAEQ--LSNELATERSTAQKN--ESARQQLERQN 1801
Query: 119 KEATDHATALRSQLDLKDNRMK-ELEAELAMAKQSLATLTKDV 160
KE LRS+L + +K + ++ +A + +A L + V
Sbjct: 1802 KE-------LRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQV 1837
Score = 35.0 bits (79), Expect = 0.091
Identities = 29/140 (20%), Positives = 67/140 (47%), Gaps = 6/140 (4%)
Query: 2 KEMLAKDLEESQGGKSSEVLSA-TELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
KE+ +K L E +G S+ S L ++AQ E+++ + QA K+ + +
Sbjct: 1802 KELRSK-LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1860
Query: 61 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
++ Q++ E +EQ +Q +++ E+A +E + + +L+R+ E
Sbjct: 1861 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEA----EEESQRINANRRKLQRELDE 1916
Query: 121 ATDHATALRSQLDLKDNRMK 140
AT+ A+ +++ ++++
Sbjct: 1917 ATESNEAMGREVNALKSKLR 1936
Score = 33.5 bits (75), Expect = 0.26
Identities = 36/158 (22%), Positives = 76/158 (48%), Gaps = 8/158 (5%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
E L + LE+ + K++ + L + A EL +A Q ++ +K+L+ + +L
Sbjct: 1213 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1272
Query: 63 SQM---QQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWE----LR 115
S+ ++ A L + +L++ + + E+E LAK+ L + + L+
Sbjct: 1273 SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ 1332
Query: 116 RQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 153
+ ++ + +T LR QL+ + N +++ E AKQ+L
Sbjct: 1333 EETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNL 1369
Score = 30.8 bits (68), Expect = 1.7
Identities = 37/187 (19%), Positives = 81/187 (43%), Gaps = 30/187 (16%)
Query: 9 LEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG------------ 56
LEE + K ++V+ A + + + A+ ++ L AMK ++
Sbjct: 785 LEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRL 844
Query: 57 -EKTDLVSQMQQLYATLESREEQL---RDFIRNYEQHRKESEDAVKALAKEKDLL----- 107
K + Q+ + ++++E++L ++ + E KE E L +EK+LL
Sbjct: 845 FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ 904
Query: 108 -------EREKWELRRQAK--EATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
E E+ +R AK E + + ++L+ +++R ++L+AE Q + L +
Sbjct: 905 AETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE 964
Query: 159 DVPKRHS 165
+ + +
Sbjct: 965 QLEEEEA 971
Score = 28.5 bits (62), Expect = 8.5
Identities = 37/177 (20%), Positives = 69/177 (38%), Gaps = 21/177 (11%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
E +L + +EV S T + + K +LA+ +L + D + L E+T
Sbjct: 1279 ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1338
Query: 63 SQMQQLYATLESREEQLRDFI-------RNYEQH-----------RKESED---AVKALA 101
+ LE L+D + +N E+H +K+ +D V+AL
Sbjct: 1339 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1398
Query: 102 KEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
+ K ++E L +Q +E L + + +L +L +Q ++ L K
Sbjct: 1399 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1455
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 50.1 bits (118), Expect = 3e-06
Identities = 38/158 (24%), Positives = 80/158 (50%), Gaps = 9/158 (5%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
+EM AK+ +E Q K + + EL+ +L QK +L K LQ ++L+ E T+L
Sbjct: 852 EEMQAKE-DELQKTKERQQKAENELK-ELEQKHSQLTEEKNLLQ------EQLQAE-TEL 902
Query: 62 VSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEA 121
++ +++ L +++++L + + E +E ED + L E+ + ++ +L Q +E
Sbjct: 903 YAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE 962
Query: 122 TDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
L+ + + ++K+LE E+ + L+K+
Sbjct: 963 EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE 1000
Score = 46.6 bits (109), Expect = 3e-05
Identities = 41/158 (25%), Positives = 72/158 (45%), Gaps = 8/158 (5%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
KE LA++L S G+++ L ++AQ E+EL + ++AM ++ + L
Sbjct: 1710 KEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL 1769
Query: 62 VSQMQQLYATLESREEQLRDFIRNYEQHRK---ESEDAVKALAKEK-DLLEREKWELRRQ 117
+++ +T + E + R ++ R E E AVK+ K LE + +L Q
Sbjct: 1770 SNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ 1829
Query: 118 AKEATDHATALRSQLDLKDNRMKEL----EAELAMAKQ 151
++ A L KD ++KE+ E E MA+Q
Sbjct: 1830 VEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 1867
Score = 44.7 bits (104), Expect = 1e-04
Identities = 39/176 (22%), Positives = 75/176 (42%), Gaps = 18/176 (10%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKA------------ 49
++ L K + +G S +L+ Q+A+ + +LA+ +E LQA A
Sbjct: 1050 RQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNA 1109
Query: 50 --DRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLL 107
+ L+G +DL + A E+Q RD E + E ED + + A +++L
Sbjct: 1110 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1169
Query: 108 EREKWEL----RRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
+ + E+ + +E H ++ ++EL +L K++ A L K+
Sbjct: 1170 AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKN 1225
Score = 39.7 bits (91), Expect = 0.004
Identities = 37/130 (28%), Positives = 58/130 (44%), Gaps = 11/130 (8%)
Query: 25 ELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL-------VSQMQQLYATLESREE 77
+L+ QL + E EL ++ A +K+L+G+ DL + ++ L +
Sbjct: 1593 QLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQA 1652
Query: 78 QLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
Q++DF R E R S D + A AKE + + Q +E A R Q DL+
Sbjct: 1653 QMKDFQRELEDAR-ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE-- 1709
Query: 138 RMKELEAELA 147
+EL ELA
Sbjct: 1710 -KEELAEELA 1718
Score = 38.9 bits (89), Expect = 0.006
Identities = 40/176 (22%), Positives = 74/176 (42%), Gaps = 25/176 (14%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
+ L L+E K + + L +QL+ +++L ++A++ +KR + E +L
Sbjct: 1345 RNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL 1404
Query: 62 VSQMQQLYATLESRE-------EQLRDFIRNYEQHR-------KESEDAVKALAKEK--- 104
Q ++ A + E ++L D + + + R K+ + LA+EK
Sbjct: 1405 TQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNIS 1464
Query: 105 ----DLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATL 156
D +R + E R + +A A AL L+ K+ ELE M K + L
Sbjct: 1465 SKYADERDRAEAEAREKETKALSLARALEEALEAKE----ELERTNKMLKAEMEDL 1516
Score = 37.7 bits (86), Expect = 0.014
Identities = 34/161 (21%), Positives = 72/161 (44%), Gaps = 9/161 (5%)
Query: 8 DLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQ 67
DLEE E + +L+++ E ++ + ++ + M +L E+ L ++
Sbjct: 954 DLEEQL---EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1010
Query: 68 LYATLESREEQLRDFIRNYEQHR---KESEDAVKALAKEKDLLEREKWELRRQAKEATDH 124
L L EE+ ++ + +H E E +K K + LE+ K +L A + +
Sbjct: 1011 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1070
Query: 125 ATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHS 165
L++Q+ ++ + E EL A LA L ++ ++++
Sbjct: 1071 IADLQAQIAELKMQLAKKEEELQAA---LARLDDEIAQKNN 1108
Score = 36.2 bits (82), Expect = 0.041
Identities = 39/163 (23%), Positives = 77/163 (47%), Gaps = 16/163 (9%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQL-AQKEQ---ELARAKEALQAMKADRKRLKGEK 58
E AK LE ++ +A R Q +KE+ ELA + A++ +++RL+
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1738
Query: 59 TDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQA 118
L ++++ +E+ +++R + EQ +E A + +K+ E + +L RQ
Sbjct: 1739 AQLEEELEEEQGNMEAMSDRVRKATQQAEQ--LSNELATERSTAQKN--ESARQQLERQN 1794
Query: 119 KEATDHATALRSQLDLKDNRMK-ELEAELAMAKQSLATLTKDV 160
KE LRS+L + +K + ++ +A + +A L + V
Sbjct: 1795 KE-------LRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQV 1830
Score = 35.0 bits (79), Expect = 0.091
Identities = 29/140 (20%), Positives = 67/140 (47%), Gaps = 6/140 (4%)
Query: 2 KEMLAKDLEESQGGKSSEVLSA-TELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
KE+ +K L E +G S+ S L ++AQ E+++ + QA K+ + +
Sbjct: 1795 KELRSK-LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1853
Query: 61 LVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKE 120
++ Q++ E +EQ +Q +++ E+A +E + + +L+R+ E
Sbjct: 1854 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEA----EEESQRINANRRKLQRELDE 1909
Query: 121 ATDHATALRSQLDLKDNRMK 140
AT+ A+ +++ ++++
Sbjct: 1910 ATESNEAMGREVNALKSKLR 1929
Score = 33.5 bits (75), Expect = 0.26
Identities = 36/158 (22%), Positives = 76/158 (48%), Gaps = 8/158 (5%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
E L + LE+ + K++ + L + A EL +A Q ++ +K+L+ + +L
Sbjct: 1206 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1265
Query: 63 SQM---QQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWE----LR 115
S+ ++ A L + +L++ + + E+E LAK+ L + + L+
Sbjct: 1266 SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ 1325
Query: 116 RQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 153
+ ++ + +T LR QL+ + N +++ E AKQ+L
Sbjct: 1326 EETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNL 1362
Score = 30.8 bits (68), Expect = 1.7
Identities = 37/187 (19%), Positives = 81/187 (43%), Gaps = 30/187 (16%)
Query: 9 LEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG------------ 56
LEE + K ++V+ A + + + A+ ++ L AMK ++
Sbjct: 778 LEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRL 837
Query: 57 -EKTDLVSQMQQLYATLESREEQL---RDFIRNYEQHRKESEDAVKALAKEKDLL----- 107
K + Q+ + ++++E++L ++ + E KE E L +EK+LL
Sbjct: 838 FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ 897
Query: 108 -------EREKWELRRQAK--EATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
E E+ +R AK E + + ++L+ +++R ++L+AE Q + L +
Sbjct: 898 AETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE 957
Query: 159 DVPKRHS 165
+ + +
Sbjct: 958 QLEEEEA 964
Score = 28.5 bits (62), Expect = 8.5
Identities = 37/177 (20%), Positives = 69/177 (38%), Gaps = 21/177 (11%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLV 62
E +L + +EV S T + + K +LA+ +L + D + L E+T
Sbjct: 1272 ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1331
Query: 63 SQMQQLYATLESREEQLRDFI-------RNYEQH-----------RKESED---AVKALA 101
+ LE L+D + +N E+H +K+ +D V+AL
Sbjct: 1332 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1391
Query: 102 KEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTK 158
+ K ++E L +Q +E L + + +L +L +Q ++ L K
Sbjct: 1392 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1448
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 49.7 bits (117), Expect = 4e-06
Identities = 39/146 (26%), Positives = 72/146 (49%), Gaps = 5/146 (3%)
Query: 16 KSSEV-LSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLES 74
KSSEV L+ + AQ ++ L +++ + +KA + L EK DL+ Q+Q TL +
Sbjct: 853 KSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLAN 912
Query: 75 REEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDL 134
EEQ I++ + + E VK L++ + E EL + ++ D L+ ++D
Sbjct: 913 VEEQCEWLIKS----KIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDD 968
Query: 135 KDNRMKELEAELAMAKQSLATLTKDV 160
+ + + E E + + LT++V
Sbjct: 969 LETMLVKSEKEKRTTEHKVKNLTEEV 994
Score = 33.5 bits (75), Expect = 0.26
Identities = 35/171 (20%), Positives = 81/171 (47%), Gaps = 13/171 (7%)
Query: 5 LAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQ 64
+ K+ EE + A + ++ A +EL + ++ + ++ R+ ++ TDL +
Sbjct: 1749 MQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKR 1808
Query: 65 MQQL--YATLESR------EEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRR 116
+ + A + SR E ++R+ E + S +A + + LER EL
Sbjct: 1809 LAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARR----LERCIKELTY 1864
Query: 117 QAKEATDHATALRSQLDLKDNRMKELEAELAMAK-QSLATLTKDVPKRHSL 166
QA+E + + +++Q+D +++ + ++ +A+ Q+ L+K ++H L
Sbjct: 1865 QAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHEL 1915
Score = 31.6 bits (70), Expect = 1.0
Identities = 35/133 (26%), Positives = 59/133 (44%), Gaps = 13/133 (9%)
Query: 1 MKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTD 60
+K+ L KD KS L +L ++ Q + A A E L + +R K D
Sbjct: 1225 VKQKLEKD-------KSDLQLEVDDLLTRVEQMTRAKANA-EKLCTLYEERLHEATAKLD 1276
Query: 61 LVSQMQQLYATLESRE-EQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAK 119
V+Q+ A +++ + +F+R E E E + L++EK R+ +LR Q +
Sbjct: 1277 KVTQLANDLAAQKTKLWSESGEFLRRLE----EKEALINQLSREKSNFTRQIEDLRGQLE 1332
Query: 120 EATDHATALRSQL 132
+ T +AL L
Sbjct: 1333 KETKSQSALAHAL 1345
Score = 30.0 bits (66), Expect = 2.9
Identities = 39/168 (23%), Positives = 64/168 (38%), Gaps = 21/168 (12%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
KE L L KS+ +LR QL ++ + + ALQ + D L+ + +
Sbjct: 1306 KEALINQLSRE---KSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEE 1362
Query: 62 VSQMQQLYATLESREEQLRDFIRNYE----QHRKESEDAVKALA--------------KE 103
+L+ TL ++ + YE Q ++ EDA K LA
Sbjct: 1363 QEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANAR 1422
Query: 104 KDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQ 151
LER + +L+ + +A +RS D + + LA KQ
Sbjct: 1423 NASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQ 1470
Score = 29.6 bits (65), Expect = 3.8
Identities = 30/145 (20%), Positives = 64/145 (44%), Gaps = 15/145 (10%)
Query: 16 KSSEVLSATELRVQLAQKE-QELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLES 74
K E L+ EL++ A ++ E ++ LQ D + + T L S +++ A E
Sbjct: 1629 KMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAER 1688
Query: 75 REEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDL 134
R L+ + + ++++E + E++LLE AT+ +Q
Sbjct: 1689 RNSLLQSELEDLRSLQEQTERGRRL--SEEELLE------------ATERINLFYTQNTS 1734
Query: 135 KDNRMKELEAELAMAKQSLATLTKD 159
++ K+LEA++A ++ + ++
Sbjct: 1735 LLSQKKKLEADVARMQKEAEEVVQE 1759
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 49.7 bits (117), Expect = 4e-06
Identities = 41/170 (24%), Positives = 75/170 (44%), Gaps = 19/170 (11%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
KE L K+ Q S + T+L+ +L++ + KE L+ K + L + TDL
Sbjct: 1320 KEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDL 1379
Query: 62 VSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREK---------- 111
Q+Q +L +E + + Y++ + E D V+ L+ + D L +EK
Sbjct: 1380 NVQLQN-SISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDW 1438
Query: 112 ------WELRRQAKEATDHATA--LRSQLDLKDNRMKELEAELAMAKQSL 153
W+ + Q++ T L+ QL+LK E + ++ + K+ L
Sbjct: 1439 SNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEEL 1488
Score = 41.6 bits (96), Expect = 0.001
Identities = 33/136 (24%), Positives = 62/136 (45%), Gaps = 10/136 (7%)
Query: 28 VQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRD---FIR 84
+QL +KEQE+A K+ + +++ + E T L + + TL +EQL+ +
Sbjct: 1064 IQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVN 1123
Query: 85 NYEQ-------HRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
+ Q H ++ E + KE L+ + EL+ A+E + L S+L D
Sbjct: 1124 SLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDE 1183
Query: 138 RMKELEAELAMAKQSL 153
+ L++ + +SL
Sbjct: 1184 EFQSLKSSHEKSNKSL 1199
Score = 38.1 bits (87), Expect = 0.011
Identities = 33/143 (23%), Positives = 65/143 (45%), Gaps = 10/143 (6%)
Query: 25 ELRVQLAQKEQELARAKEALQAMKAD----RKR---LKGEKTDLVSQMQQLYATLESREE 77
EL++QL K +E E + +K + KR LKGE D S+M++ + LE+ +
Sbjct: 1462 ELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELK 1521
Query: 78 QLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
I E H + +++L ++L+ + + KE + + KDN
Sbjct: 1522 SQTARIMELEDHITQKTIEIESL---NEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDN 1578
Query: 138 RMKELEAELAMAKQSLATLTKDV 160
R+KE E ++ + + ++ ++
Sbjct: 1579 RVKEAEEKILTLENQVYSMKAEL 1601
Score = 37.7 bits (86), Expect = 0.014
Identities = 28/134 (20%), Positives = 65/134 (48%), Gaps = 7/134 (5%)
Query: 25 ELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIR 84
+L + L ++++ L + ++ ++AD KR +GE + Q +S + + +
Sbjct: 760 QLELLLKERDKHLKEHQAHVENLEADIKRSEGE----LQQASAKLDVFQSYQSATHEQTK 815
Query: 85 NYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEA 144
YE+ + + + L E+ LL ++ E+ Q K+ A + Q+ + M++LE
Sbjct: 816 AYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQV---QDLMQQLEK 872
Query: 145 ELAMAKQSLATLTK 158
+ + +Q + +LT+
Sbjct: 873 QNSEMEQKVKSLTQ 886
Score = 37.7 bits (86), Expect = 0.014
Identities = 34/151 (22%), Positives = 70/151 (46%), Gaps = 20/151 (13%)
Query: 7 KDLEESQGGKSSEVLSATELRVQLAQKEQELARA-KEAL-QAMKADRKRLKGEKTDLVSQ 64
+DLE +++ E QLAQKEQEL KE + +A + + + L+ + +
Sbjct: 1984 EDLELKHNSTLKQLMR--EFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQ----EE 2037
Query: 65 MQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKE-----KDLLEREKWELRRQAK 119
QL + +++ L+ + YE+ E+ + A ++ ++L ++ + +L ++
Sbjct: 2038 TNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEEN 2097
Query: 120 EATDHATALRSQLDL-------KDNRMKELE 143
D+ T + Q L D+++KE E
Sbjct: 2098 PGNDNVTIMELQTQLAQKTTLISDSKLKEQE 2128
Score = 35.0 bits (79), Expect = 0.091
Identities = 41/184 (22%), Positives = 76/184 (41%), Gaps = 31/184 (16%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATE---LRVQLAQKEQELARAKEALQAMKADRKRLKGEK 58
+ +L + E Q K L +E L+ QL ++ QEL + K+ A K +
Sbjct: 292 ENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDA 351
Query: 59 TDLVSQMQQ------------LYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDL 106
+L+ Q++Q ++ TLE +EE++ +Q + E+ L ++K+
Sbjct: 352 KNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEE----LREQKEK 407
Query: 107 LEREKWELRRQAKEATDHATALRSQLDLK-DNRMK-----------ELEAELAMAKQSLA 154
ER +E +A R +L + D ++K L+ EL+ KQ +
Sbjct: 408 SERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVV 467
Query: 155 TLTK 158
+ K
Sbjct: 468 DVMK 471
Score = 35.0 bits (79), Expect = 0.091
Identities = 47/194 (24%), Positives = 80/194 (41%), Gaps = 31/194 (15%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKE----QELARAKEALQAMKADRKRLKGEK 58
EM +++ + + ELR Q + E +EL +A Q + R++LK E
Sbjct: 378 EMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAE- 436
Query: 59 TDLVSQMQQLYATLESREEQLRDFIRN---------YEQHRKESEDAVKALAK--EKDLL 107
M + T+E E+ R ++ + +K SE+ + L K EK+L
Sbjct: 437 ------MDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELA 490
Query: 108 ERE-----KWELRRQAKEATDHATALRSQLD-LKDNRMKELEAELAMAK---QSLATLTK 158
+E K + R + + +SQ + LK ++ KE + LA+ + Q A LT+
Sbjct: 491 RKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTE 550
Query: 159 DVPKRHSLAMPGET 172
K L ET
Sbjct: 551 SENKLRDLQQEAET 564
Score = 33.9 bits (76), Expect = 0.20
Identities = 41/171 (23%), Positives = 77/171 (45%), Gaps = 14/171 (8%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
KE L KD E E+ T ++ + Q E E + + E + +KA R +L+ E + L
Sbjct: 653 KETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELE-SLSSELSEVLKA-RHKLEEELSVL 710
Query: 62 VSQMQQLYATLESR--------EEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWE 113
Q ++ LE++ ++Q+ I+ +E + +E KAL + + LE E
Sbjct: 711 KDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTE---KALKDQINQLELLLKE 767
Query: 114 LRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRH 164
+ KE H L + + + +++ A+L + QS + T + K +
Sbjct: 768 RDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVF-QSYQSATHEQTKAY 817
Score = 33.5 bits (75), Expect = 0.26
Identities = 27/132 (20%), Positives = 59/132 (44%), Gaps = 16/132 (12%)
Query: 32 QKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRK 91
+K+ + A+E + ++ +K E +++ + +++S+EE+L+ + R
Sbjct: 1575 EKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKAL-----EDRL 1629
Query: 92 ESEDAV-----------KALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMK 140
ESE A K A +K LL + + + + K H + L ++L ++ +
Sbjct: 1630 ESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVH 1689
Query: 141 ELEAELAMAKQS 152
LE +L + S
Sbjct: 1690 ILEEKLKSVESS 1701
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 49.3 bits (116), Expect = 5e-06
Identities = 33/135 (24%), Positives = 68/135 (50%), Gaps = 5/135 (3%)
Query: 27 RVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLY---ATLESREEQLRDFI 83
R+Q A++ E A +K A +++ ++RL+GE DL+ +++ + ATL+ ++ +
Sbjct: 1400 RLQEAEENTETANSKCA--SLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVL 1457
Query: 84 RNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELE 143
++Q ES+ ++A KE L E +++R +E D LR + + +L
Sbjct: 1458 AEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLT 1517
Query: 144 AELAMAKQSLATLTK 158
++A ++L K
Sbjct: 1518 EQIAETGKNLQEAEK 1532
Score = 47.8 bits (112), Expect = 1e-05
Identities = 38/161 (23%), Positives = 70/161 (43%), Gaps = 17/161 (10%)
Query: 16 KSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG-------EKTDLVSQMQQL 68
K +L + E ++A +++ R KE L +A RK L+ EK DL Q+Q
Sbjct: 839 KIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSE 898
Query: 69 YATLESREEQLRDFIRN----------YEQHRKESEDAVKALAKEKDLLEREKWELRRQA 118
L EE+ I++ + +E E+ L +K LE + L+R
Sbjct: 899 TENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDI 958
Query: 119 KEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
+ T + + +N++K L E+ +++++ LTK+
Sbjct: 959 DDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKE 999
Score = 42.7 bits (99), Expect = 4e-04
Identities = 49/180 (27%), Positives = 81/180 (45%), Gaps = 22/180 (12%)
Query: 1 MKEMLAKDLEESQGGKSSEVLSATELRVQLAQ-------KEQELARAKEALQAMKADRKR 53
+KE LA + E + G E L E++V L Q EQEL A + +Q + +
Sbjct: 1671 LKEQLA--IVERRNGLLLEELE--EMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTS 1726
Query: 54 LKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDL---LERE 110
L K L + + Q A +E+ ++ R+ ++ ++ + L KE+D LER
Sbjct: 1727 LINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM 1786
Query: 111 KWELRRQAKEAT---DHATAL-----RSQLDLKDNRMKELEAELAMAKQSLATLTKDVPK 162
K L + K+ D A L + Q+ +NR++ELE EL + ++ A K K
Sbjct: 1787 KKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHK 1846
Score = 37.4 bits (85), Expect = 0.018
Identities = 40/205 (19%), Positives = 84/205 (40%), Gaps = 49/205 (23%)
Query: 8 DLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQ 67
+L + Q E + + + + ++ + + + +E ++A R +++ +++DL ++++
Sbjct: 1090 ELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEE 1149
Query: 68 LYATLES--------------REEQLRDFIRNYE----QH-------RKESEDAVKALAK 102
+ LE RE + + R+ E QH RK+ D+V L +
Sbjct: 1150 ISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGE 1209
Query: 103 E-------KDLLEREKWELRRQAKEATDHATALR-----------------SQLDLKDNR 138
+ K LE+EK EL+ + + + AL S++ KD +
Sbjct: 1210 QIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQ 1269
Query: 139 MKELEAELAMAKQSLATLTKDVPKR 163
+L +L M K L T ++ R
Sbjct: 1270 QTQLIHDLNMQKARLQTQNGELSHR 1294
Score = 33.5 bits (75), Expect = 0.26
Identities = 35/142 (24%), Positives = 62/142 (43%), Gaps = 9/142 (6%)
Query: 18 SEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREE 77
SE+ + E + QL +L K LQ + EK L+SQ+ + L + E
Sbjct: 1261 SEIKAKDEQQTQLIH---DLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLE 1317
Query: 78 QLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
+L+ + + + A+++ + DLL RE++E ++AK A + + +
Sbjct: 1318 ELKRQMEEETKAKNAMAHALQSSRHDCDLL-REQYEEEQEAKAELQRALSKANSEVAQWR 1376
Query: 138 RMKELEA-----ELAMAKQSLA 154
E +A EL AK+ LA
Sbjct: 1377 TKYETDAIQRTEELEEAKKKLA 1398
Score = 32.3 bits (72), Expect = 0.59
Identities = 25/134 (18%), Positives = 56/134 (41%), Gaps = 3/134 (2%)
Query: 25 ELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIR 84
EL ++ +KE +++ ++ QA+ + LK + + + L+S
Sbjct: 1290 ELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLRE 1349
Query: 85 NYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEA 144
YE+ ++ + +AL+K + + + + A + T+ + +L R++E E
Sbjct: 1350 QYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL---AQRLQEAEE 1406
Query: 145 ELAMAKQSLATLTK 158
A A+L K
Sbjct: 1407 NTETANSKCASLEK 1420
Score = 31.2 bits (69), Expect = 1.3
Identities = 29/126 (23%), Positives = 55/126 (43%), Gaps = 11/126 (8%)
Query: 25 ELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIR 84
E+ +QL +++A ++ L+ ++ G+ D + + E +EQL R
Sbjct: 1628 EMEIQLGHSNRQMAETQKHLRTVQ-------GQLKDSQLHLDDALRSNEDLKEQLAIVER 1680
Query: 85 NYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEA 144
+E E+ AL + ER + ++ +A+D L SQ N K+LEA
Sbjct: 1681 RNGLLLEELEEMKVALEQT----ERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEA 1736
Query: 145 ELAMAK 150
++A +
Sbjct: 1737 DIAQCQ 1742
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 49.3 bits (116), Expect = 5e-06
Identities = 45/161 (27%), Positives = 70/161 (43%), Gaps = 17/161 (10%)
Query: 16 KSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKG-------EKTDLVSQMQQL 68
K +L + + +LA EL + AL A +A R+ L+ EK DL Q+Q
Sbjct: 884 KMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAE 943
Query: 69 YATLESREEQLRDFIRNYEQ---------HRKESEDAVKA-LAKEKDLLEREKWELRRQA 118
L EE+ I++ Q R E E+ V A LA + LE E EL++
Sbjct: 944 QDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDI 1003
Query: 119 KEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
+ + +N++K L E+A +S+A LTK+
Sbjct: 1004 DDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKE 1044
Score = 42.7 bits (99), Expect = 4e-04
Identities = 45/170 (26%), Positives = 75/170 (44%), Gaps = 18/170 (10%)
Query: 4 MLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVS 63
+LA +LEE + L E +LA EQEL A E L + + L +K L +
Sbjct: 1729 LLAAELEELRAA-----LEQGERSRRLA--EQELLEATERLNLLHSQNTGLLNQKKKLEA 1781
Query: 64 QMQQLYATLESREEQLRDFIRNYE----------QHRKESEDAVKALAKEKDLLEREKWE 113
+ QL +E ++ R+ + + K+ +D L + K LE+ E
Sbjct: 1782 DLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRE 1841
Query: 114 LRRQAKEATDHAT-ALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPK 162
L+ + +EA A + Q+ + +++ELEAEL ++ A K V K
Sbjct: 1842 LQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRK 1891
Score = 42.4 bits (98), Expect = 6e-04
Identities = 32/132 (24%), Positives = 61/132 (46%), Gaps = 7/132 (5%)
Query: 27 RVQLAQKEQELARAKEALQAMKAD----RKRLKGEKTDLVSQMQQLYATL---ESREEQL 79
+VQL K +EL+ E + + AD R++L+ E T+L + L TL E ++
Sbjct: 961 KVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQAT 1020
Query: 80 RDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRM 139
+ ++N + +++V L KEK L+ + + D +AL + ++
Sbjct: 1021 ENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQV 1080
Query: 140 KELEAELAMAKQ 151
++LE L K+
Sbjct: 1081 EDLECSLEQEKK 1092
Score = 40.4 bits (93), Expect = 0.002
Identities = 38/146 (26%), Positives = 72/146 (49%), Gaps = 7/146 (4%)
Query: 2 KEMLAKDLEE--SQGGKSSEVLSATELRVQLAQKEQELARAKEALQA-MKADRKRLKGEK 58
K + A+ LEE Q + S+ SA VQ + + +L R + +A +A+ +RL +
Sbjct: 1354 KALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKA 1413
Query: 59 TDLVSQMQQLY-ATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQ 117
V+Q + Y A R E+L + + +E+E+ V+A + LE+ K L+ +
Sbjct: 1414 NAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTE 1473
Query: 118 AKEAT---DHATALRSQLDLKDNRMK 140
+++ T + AT+ + LD K ++
Sbjct: 1474 SEDVTLELERATSAAAALDKKQRHLE 1499
Score = 40.0 bits (92), Expect = 0.003
Identities = 37/159 (23%), Positives = 72/159 (45%), Gaps = 11/159 (6%)
Query: 2 KEMLAKDLEESQGGKSS-----EVLSATELRVQLAQKEQ--ELARAKEALQAMKADRKRL 54
K+ LA L+E++ G + L +LR+Q ++ EL RA A A+ ++ L
Sbjct: 1439 KKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHL 1498
Query: 55 KGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWEL 114
+ + Q +++ LE+ + + R + R E+A++AL + L+RE L
Sbjct: 1499 ERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEAL----ETLKRENKNL 1554
Query: 115 RRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSL 153
+ + + TD + + + K LE E + + +L
Sbjct: 1555 QEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAAL 1593
Score = 38.9 bits (89), Expect = 0.006
Identities = 62/296 (20%), Positives = 113/296 (38%), Gaps = 30/296 (10%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQ-------AMKADRKRL 54
K L DL+ +Q + +L +L +K+ EL++ ++ M+ K L
Sbjct: 1101 KRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKEL 1160
Query: 55 KGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWEL 114
+ +L +++ A E+Q + R E+ + E+A A A +++ + + EL
Sbjct: 1161 QARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAEL 1220
Query: 115 RRQAKEATDHATALRSQLDLKDNRMKELE--AELAMAKQSLATLTKDVPKRHSLAMPGET 172
R +E + ALR + + R K+ E AEL SL + + + K S
Sbjct: 1221 GRLRRELEE--AALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVD 1278
Query: 173 VLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAA 232
L N E + +A R + L ++V + ++DAS
Sbjct: 1279 DLAANVETLTRAKASAEKLCRTYEDQL---------SEAKIKVEELQRQ----LADASTQ 1325
Query: 233 EGDRSSTPSDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQKRKKKKEK 288
G + +++ L + S G QSLE+L Q ++ K K
Sbjct: 1326 RGRLQTESGELSRLLEEKECLISQLSRGKAL------AAQSLEELRRQLEEESKAK 1375
Score = 37.7 bits (86), Expect = 0.014
Identities = 37/141 (26%), Positives = 65/141 (46%), Gaps = 13/141 (9%)
Query: 24 TELRVQLAQKEQELARA---KEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLR 80
+E ++++ + +++LA A + LQ + RL EK L+SQ+ + A E+LR
Sbjct: 1306 SEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELR 1365
Query: 81 DFIRNYEQHRKESEDAVKALAKEKDLLERE-------KWELRRQAKEATDHATALRSQLD 133
+ + + AV+AL + DLL + + EL+R +A RS+ +
Sbjct: 1366 RQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYE 1425
Query: 134 LKDNRMKELEAELAMAKQSLA 154
+ E EL AK+ LA
Sbjct: 1426 ADAIQRTE---ELEEAKKKLA 1443
Score = 37.4 bits (85), Expect = 0.018
Identities = 53/188 (28%), Positives = 86/188 (45%), Gaps = 48/188 (25%)
Query: 6 AKDLEESQGGKSSEVLSATELRV--QLAQKEQELA-------RAKEALQA-MKAD----- 50
A +LEE++ + LS + V +LA+K++E A RA E+LQA + A+
Sbjct: 1599 ALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARN 1658
Query: 51 -----RKRLKGEKTDLVSQMQQLYATLESREEQLRDFI-----------RNYEQH-RKES 93
+K+++G+ DL ++Q +AT ++ E Q + R+ EQ E
Sbjct: 1659 EALRLKKKMEGDLNDL--ELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAEL 1716
Query: 94 EDAVKALAKEKDLLEREKWELR--------------RQAKEATDHATALRSQLDLKDNRM 139
+ +AL + LL E ELR ++ EAT+ L SQ N+
Sbjct: 1717 HEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQK 1776
Query: 140 KELEAELA 147
K+LEA+LA
Sbjct: 1777 KKLEADLA 1784
Score = 35.4 bits (80), Expect = 0.070
Identities = 40/163 (24%), Positives = 70/163 (42%), Gaps = 38/163 (23%)
Query: 2 KEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDL 61
+E + ++LE +Q + S L R++ +E A EAL+ +K + K L+ E +DL
Sbjct: 1509 EEEMQRELEAAQ--RESRGLGTELFRLRHGHEE-----ALEALETLKRENKNLQEEISDL 1561
Query: 62 VSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEA 121
Q+ S +++ L K K LE EK E++ +EA
Sbjct: 1562 TDQVSL-------------------------SGKSIQELEKTKKALEGEKSEIQAALEEA 1596
Query: 122 -----TDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
+ LR QL+L + E++ +LA + A L ++
Sbjct: 1597 EGALELEETKTLRIQLELSQVK-AEVDRKLAEKDEECANLRRN 1638
Score = 30.8 bits (68), Expect = 1.7
Identities = 28/136 (20%), Positives = 65/136 (47%), Gaps = 7/136 (5%)
Query: 1 MKEMLAKDLEESQ-----GGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKRLK 55
++E+ A+ LEE++ GGK ++R A+ + E + EAL+ ++ +R+K
Sbjct: 1839 VRELQAR-LEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVK 1897
Query: 56 GEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELR 115
E + ++ A ++ ++L+ +++Y++ +E+E + + E +
Sbjct: 1898 -ELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAE 1956
Query: 116 RQAKEATDHATALRSQ 131
+A A A LR++
Sbjct: 1957 ERADMAETQANKLRAR 1972
Score = 30.4 bits (67), Expect = 2.2
Identities = 25/128 (19%), Positives = 60/128 (46%), Gaps = 4/128 (3%)
Query: 26 LRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRN 85
L+ +++ +++ + +++Q ++ +K L+GEK+++ + +++ LE E +
Sbjct: 1554 LQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLE 1613
Query: 86 YEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQ-LDLK---DNRMKE 141
Q + E + + +E L R + + D T R++ L LK + + +
Sbjct: 1614 LSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLND 1673
Query: 142 LEAELAMA 149
LE +L A
Sbjct: 1674 LELQLGHA 1681
Score = 28.5 bits (62), Expect = 8.5
Identities = 37/168 (22%), Positives = 69/168 (41%), Gaps = 11/168 (6%)
Query: 3 EMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADR-KRLKGEKTDL 61
+ L D + + E + EL+ L++ E+A+ + +A R + L+ K L
Sbjct: 1383 QALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKL 1442
Query: 62 VSQMQQLYATLESREEQLRDFIRNYEQHRKESED----------AVKALAKEKDLLEREK 111
++Q+ +E+ + + + + ESED A AL K++ LER
Sbjct: 1443 ALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERAL 1502
Query: 112 WELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKD 159
E RRQ +E A + + + L A ++L TL ++
Sbjct: 1503 EERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRE 1550
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.125 0.345
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,368,889
Number of Sequences: 37866
Number of extensions: 569306
Number of successful extensions: 6645
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 349
Number of HSP's successfully gapped in prelim test: 661
Number of HSP's that attempted gapping in prelim test: 3481
Number of HSP's gapped (non-prelim): 3002
length of query: 327
length of database: 18,247,518
effective HSP length: 103
effective length of query: 224
effective length of database: 14,347,320
effective search space: 3213799680
effective search space used: 3213799680
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.