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Search of human proteins with 62865887
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62865887 G protein-coupled receptor 54 [Homo sapiens]
(398 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62865887 G protein-coupled receptor 54 [Homo sapiens] 813 0.0
gi|4503905 galanin receptor 2 [Homo sapiens] 204 1e-52
gi|4503907 galanin receptor 3 [Homo sapiens] 202 6e-52
gi|167000885 galanin receptor 1 [Homo sapiens] 194 1e-49
gi|4557861 somatostatin receptor 3 [Homo sapiens] 177 1e-44
gi|149944554 somatostatin receptor 4 [Homo sapiens] 171 1e-42
gi|4557865 somatostatin receptor 5 [Homo sapiens] 166 3e-41
gi|63477962 opioid receptor, delta 1 [Homo sapiens] 166 3e-41
gi|4505513 opiate receptor-like 1 [Homo sapiens] 163 2e-40
gi|33286424 opiate receptor-like 1 [Homo sapiens] 163 2e-40
gi|4557857 somatostatin receptor 1 [Homo sapiens] 159 3e-39
gi|39725940 opioid receptor, kappa 1 [Homo sapiens] 159 5e-39
gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens] 155 6e-38
gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens] 155 6e-38
gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens] 155 6e-38
gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens] 155 6e-38
gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens] 155 6e-38
gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens] 155 6e-38
gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens] 155 6e-38
gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens] 155 6e-38
gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens] 155 6e-38
gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens] 155 6e-38
gi|4758474 G protein-coupled receptor 10 [Homo sapiens] 152 7e-37
gi|4557859 somatostatin receptor 2 [Homo sapiens] 145 8e-35
gi|53828924 G protein-coupled receptor 7 [Homo sapiens] 145 8e-35
gi|222080095 orexin receptor 1 [Homo sapiens] 144 2e-34
gi|30581164 neuropeptides B/W receptor 2 [Homo sapiens] 141 1e-33
gi|222080109 orexin receptor 2 [Homo sapiens] 138 1e-32
gi|11545887 neuropeptide FF receptor 1 [Homo sapiens] 138 1e-32
gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens] 132 4e-31
>gi|62865887 G protein-coupled receptor 54 [Homo sapiens]
Length = 398
Score = 813 bits (2099), Expect = 0.0
Identities = 398/398 (100%), Positives = 398/398 (100%)
Query: 1 MHTVATSGPNASWGAPANASGCPGCGANASDGPVPSPRAVDAWLVPLFFAALMLLGLVGN 60
MHTVATSGPNASWGAPANASGCPGCGANASDGPVPSPRAVDAWLVPLFFAALMLLGLVGN
Sbjct: 1 MHTVATSGPNASWGAPANASGCPGCGANASDGPVPSPRAVDAWLVPLFFAALMLLGLVGN 60
Query: 61 SLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNY 120
SLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNY
Sbjct: 61 SLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNY 120
Query: 121 IQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAPVLAL 180
IQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAPVLAL
Sbjct: 121 IQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAPVLAL 180
Query: 181 HRLSPGPRAYCSEAFPSRALERAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPAP 240
HRLSPGPRAYCSEAFPSRALERAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPAP
Sbjct: 181 HRLSPGPRAYCSEAFPSRALERAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPAP 240
Query: 241 ADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYA 300
ADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYA
Sbjct: 241 ADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYA 300
Query: 301 AYALKTWAHCMSYSNSALNPLLYAFLGSHFRQAFRRVCPCAPRRPRRPRRPGPSDPAAPH 360
AYALKTWAHCMSYSNSALNPLLYAFLGSHFRQAFRRVCPCAPRRPRRPRRPGPSDPAAPH
Sbjct: 301 AYALKTWAHCMSYSNSALNPLLYAFLGSHFRQAFRRVCPCAPRRPRRPRRPGPSDPAAPH 360
Query: 361 AELLRLGSHPAPARAQKPGSSGLAARGLCVLGEDNAPL 398
AELLRLGSHPAPARAQKPGSSGLAARGLCVLGEDNAPL
Sbjct: 361 AELLRLGSHPAPARAQKPGSSGLAARGLCVLGEDNAPL 398
>gi|4503905 galanin receptor 2 [Homo sapiens]
Length = 387
Score = 204 bits (518), Expect = 1e-52
Identities = 124/321 (38%), Positives = 172/321 (53%), Gaps = 15/321 (4%)
Query: 18 NASGCPGCGANASDGPVPSPRAVDAWLVPLFFAALMLLGLVGNSLVIYVICRHKPMRTVT 77
N SGCPG G NAS +A +VPL FA + L+G VGN+LV+ V+ R + T
Sbjct: 2 NVSGCPGAG-NASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTT 60
Query: 78 NFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNYIQQVSVQATCATLTAMS 137
N +I NL D+ F+LCCVPF A +Y L GWV G +CK V+++ +++ A+ TL A+S
Sbjct: 61 NLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVS 120
Query: 138 VDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAPVLALHRLSPGPRAYCSEAFPS 197
+DR+ +PL + RTPR ALA IW S S P L+ +R S S
Sbjct: 121 LDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWS 180
Query: 198 RALERAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPAPADSALQGQVLAERAGAV 257
RA + + YLLP+L YA LR+L R AV P A S A RA
Sbjct: 181 APRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWR-AVDPVAAGSG------ARRA--- 230
Query: 258 RAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYAAYALKTWAHCMSYSNSA 317
+ KV+R++ V LF CW P ++ G P + A YAL+ +H +SY+NS
Sbjct: 231 KRKVTRMILIVAALFCLCWMPHHALILCVWFGQ----FPLTRATYALRILSHLVSYANSC 286
Query: 318 LNPLLYAFLGSHFRQAFRRVC 338
+NP++YA + HFR+ FR +C
Sbjct: 287 VNPIVYALVSKHFRKGFRTIC 307
>gi|4503907 galanin receptor 3 [Homo sapiens]
Length = 368
Score = 202 bits (513), Expect = 6e-52
Identities = 139/382 (36%), Positives = 188/382 (49%), Gaps = 38/382 (9%)
Query: 27 ANASDGPVPSPRAVDAWLVPLFFAALMLLGLVGNSLVIYVICRHKPMR-----TVTNFYI 81
A+A + + SP +V A VP+ FA + LLG VGN LV+ V+ + P + T+ +I
Sbjct: 2 ADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFI 61
Query: 82 ANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNYIQQVSVQATCATLTAMSVDRW 141
NLA D+ F+LCCVPF A +Y L W+ G +CK V+ + +++ A+ TL A+SVDR+
Sbjct: 62 LNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRY 121
Query: 142 YVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAPVLALH-RLSPGPRAYCSEAFPSRAL 200
PLR+ RTPR A A +W+ +A SAP L+ + + G C A+ A
Sbjct: 122 LAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWED-AR 180
Query: 201 ERAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPAPADSALQGQVLAERAGAVRAK 260
RA + A YLLP+ Y LR L AV PA G AE +
Sbjct: 181 RRALDVATFAAGYLLPVAVVSLAYGRTLRFLW-AAVGPA-------GAAAAEARRRATGR 232
Query: 261 VSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPR---SYAAYALKTWAHCMSYSNSA 317
R + AV L+A CWGP ++ W+ R S A YA + +HC++Y+NS
Sbjct: 233 AGRAMLAVAALYALCWGPHHALILC-------FWYGRFAFSPATYACRLASHCLAYANSC 285
Query: 318 LNPLLYAFLGSHFRQAFRRVCPCAPRRPRRPRR------------PGPSDPAAPHAELLR 365
LNPL+YA HFR FRR+ PC RR R RR PG A P LL
Sbjct: 286 LNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLL- 344
Query: 366 LGSHPAPARAQKPGSSGLAARG 387
G P + P G AARG
Sbjct: 345 AGGGQGPEPREGPVHGGEAARG 366
>gi|167000885 galanin receptor 1 [Homo sapiens]
Length = 349
Score = 194 bits (493), Expect = 1e-49
Identities = 121/344 (35%), Positives = 186/344 (54%), Gaps = 40/344 (11%)
Query: 10 NASWGAPANASGCPGCGANASDGPVPSPR---AVDAWLVPLFFAALMLLGLVGNSLVIYV 66
NASW P P P P V+ ++ + F + LG++GNSLVI V
Sbjct: 12 NASWPEPP--------------APEPGPLFGIGVENFVTLVVFGLIFALGVLGNSLVITV 57
Query: 67 ICRHKP--MRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNYIQQV 124
+ R KP R+ TN +I NL+ D+ +LL C+PF A +Y LP WVLG F+CKF++Y V
Sbjct: 58 LARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTV 117
Query: 125 SVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAPVLALHRLS 184
S+ + TL AMSVDR+ V R+ R R AL IW S A+++PV A H+
Sbjct: 118 SMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCIWALSIAMASPV-AYHQGL 176
Query: 185 PGPRA----YCSEAFPSRALERAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPAP 240
PRA +C E +P ++A+ + + YLLPLL C CYA +L HL +
Sbjct: 177 FHPRASNQTFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHK------- 229
Query: 241 ADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYA 300
+ + +++++ A + K ++ V VV++F W P + + G P + A
Sbjct: 230 -----KLKNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGV----FPLTPA 280
Query: 301 AYALKTWAHCMSYSNSALNPLLYAFLGSHFRQAFRRVCPCAPRR 344
++ + AHC++YSNS++NP++YAFL +FR+A+++V C R+
Sbjct: 281 SFLFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHIRK 324
>gi|4557861 somatostatin receptor 3 [Homo sapiens]
Length = 418
Score = 177 bits (449), Expect = 1e-44
Identities = 124/362 (34%), Positives = 169/362 (46%), Gaps = 27/362 (7%)
Query: 6 TSGP-NASWGAPANASGCPGCGANASDGPVPSPRAVDAWLVPLFFAALMLLGLVGNSLVI 64
TS P NAS P +A+ N S GP P+ AV L+PL + + ++GL+GNSLVI
Sbjct: 12 TSEPENASSAWPPDATL-----GNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVI 66
Query: 65 YVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNYIQQV 124
YV+ RH +VTN YI NLA D F+L +PF A L W G MC+ V + +
Sbjct: 67 YVVLRHTASPSVTNVYILNLALADELFML-GLPFLAAQNALSYWPFGSLMCRLVMAVDGI 125
Query: 125 SVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAPVLALHRLS 184
+ + LT MSVDR+ V P R+ RT +A VS ++WV SA V PV+ +
Sbjct: 126 NQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVP 185
Query: 185 PG-PRAYCSEAFPSRALERAFALYNLLALYLLPLLATCACY---AAMLRHLGRVAVRPAP 240
G + P+ A F +Y + PLL C CY +R GR P+
Sbjct: 186 RGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPS- 244
Query: 241 ADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYA 300
+R +V+R+V AVV LF CW P + ++ + P P A
Sbjct: 245 ----------CQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPL----PEEPA 290
Query: 301 AYALKTWAHCMSYSNSALNPLLYAFLGSHFRQAFRRVCPCAPRRPRRPRRPGPSDPAAPH 360
+ L + Y+NS NP+LY FL F+Q FRRV P R R + P P
Sbjct: 291 FFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVL-LRPSRRVRSQEPTVGPPEKTE 349
Query: 361 AE 362
E
Sbjct: 350 EE 351
>gi|149944554 somatostatin receptor 4 [Homo sapiens]
Length = 388
Score = 171 bits (433), Expect = 1e-42
Identities = 114/333 (34%), Positives = 170/333 (51%), Gaps = 24/333 (7%)
Query: 8 GPNASWGAPANASGCPGCGANASDGPVPSPRAVDAWLVPLFFAALMLLGLVGNSLVIYVI 67
G +W + ANAS P A GP + RA + +A + L+GLVGN+LVI+VI
Sbjct: 14 GLGTAWPSAANASSAPAEAEEAVAGPGDA-RAAGMVAIQCIYALVCLVGLVGNALVIFVI 72
Query: 68 CRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNYIQQVSVQ 127
R+ M+T TN Y+ NLA D F+L VPF A L W G +C+ V + +++
Sbjct: 73 LRYAKMKTATNIYLLNLAVADELFMLS-VPFVASSAALRHWPFGSVLCRAVLSVDGLNMF 131
Query: 128 ATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAPVLALHRLSP-- 185
+ LT +SVDR+ V PLRA R P +A ++L +W+ S V+ P+ P
Sbjct: 132 TSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPAR 191
Query: 186 -GPRAYCSEAFPSRALERAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPAPADSA 244
G C+ +P A F +Y L +LLP+LA CY ++ + VA+R +
Sbjct: 192 GGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALR-----AG 246
Query: 245 LQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYAAYAL 304
Q + +E+ K++RLV VV++F CW P F V+Q L + + +L
Sbjct: 247 WQQRRRSEK------KITRLVLMVVVVFVLCWMP---FYVVQLLNLFVTSLDATVNHVSL 297
Query: 305 KTWAHCMSYSNSALNPLLYAFLGSHFRQAFRRV 337
+SY+NS NP+LY FL +FR+ F+RV
Sbjct: 298 -----ILSYANSCANPILYGFLSDNFRRFFQRV 325
>gi|4557865 somatostatin receptor 5 [Homo sapiens]
Length = 364
Score = 166 bits (421), Expect = 3e-41
Identities = 125/376 (33%), Positives = 176/376 (46%), Gaps = 32/376 (8%)
Query: 12 SWGAPANASGCPGCGANASDGPVPSPRAVDAWLVPLFFAALMLLGLVGNSLVIYVICRHK 71
SW A + + G GP PS A A LVP+ + + GL GN+LVIYV+ R
Sbjct: 11 SWNASSPGAASGGGDNRTLVGPAPSAGA-RAVLVPVLYLLVCAAGLGGNTLVIYVVLRFA 69
Query: 72 PMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNYIQQVSVQATCA 131
M+TVTN YI NLA DV ++L +PF A W G +C+ V + V+ +
Sbjct: 70 KMKTVTNIYILNLAVADVLYMLG-LPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVF 128
Query: 132 TLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAPVLALHRLSPGPRAYC 191
LT MSVDR+ V PL + R PR+A S + WV S +S P+L + G
Sbjct: 129 CLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQEGGTCNA 188
Query: 192 SEAFPSRALERAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPAPADSALQGQVLA 251
S P F +Y + + PLL C CY ++ V VR A
Sbjct: 189 SWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIV-----VKVRAA-----------G 232
Query: 252 ERAGAVR----AKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYAAYALKTW 307
R G VR KV+R+V VVL+FA CW P F + + A + P+ A+ L +
Sbjct: 233 VRVGCVRRRSERKVTRMVLVVVLVFAGCWLP---FFTVNIVNLAVAL-PQEPASAGLYFF 288
Query: 308 AHCMSYSNSALNPLLYAFLGSHFRQAFRRVCPCAPRRPRRPRRPGPSDPAAPHAELLRLG 367
+SY+NS NP+LY FL +FRQ+F++V C R+ +D P + +R
Sbjct: 289 VVILSYANSCANPVLYGFLSDNFRQSFQKVL-CL----RKGSGAKDADATEPRPDRIRQQ 343
Query: 368 SHPAPARAQKPGSSGL 383
P A + ++GL
Sbjct: 344 QEATPP-AHRAAANGL 358
>gi|63477962 opioid receptor, delta 1 [Homo sapiens]
Length = 372
Score = 166 bits (421), Expect = 3e-41
Identities = 116/347 (33%), Positives = 173/347 (49%), Gaps = 34/347 (9%)
Query: 17 ANASGCPGCGANASDGPVPSPRAVD----AWLVPLFFAALMLLGLVGNSLVIYVICRHKP 72
A S CP GANAS GP P R+ A + ++A+ +GL+GN LV++ I R+
Sbjct: 22 AYPSACPSAGANAS-GP-PGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTK 79
Query: 73 MRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNYIQQVSVQATCAT 132
M+T TN YI NLA D +PF + Y + W G+ +CK V I ++ + T
Sbjct: 80 MKTATNIYIFNLALADA-LATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFT 138
Query: 133 LTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAPVLALHRLSPGPRA-YC 191
LT MSVDR+ P++AL RTP A +++ IWV ++ V P++ + P A C
Sbjct: 139 LTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVC 198
Query: 192 SEAFPSRA--LERAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPAPADSALQGQV 249
FPS + + + L +++P+L CY ML L V + L G
Sbjct: 199 MLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRL--------LSGSK 250
Query: 250 LAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYAAYALKTWAH 309
+R+ +++R+V VV F CW PI +F+++ L P AA L
Sbjct: 251 EKDRS---LRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHL---CI 304
Query: 310 CMSYSNSALNPLLYAFLGSHFRQAFRRVC--PCAPRRPRRPRRPGPS 354
+ Y+NS+LNP+LYAFL +F++ FR++C PC RP PS
Sbjct: 305 ALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG--------RPDPS 343
>gi|4505513 opiate receptor-like 1 [Homo sapiens]
Length = 370
Score = 163 bits (413), Expect = 2e-40
Identities = 118/335 (35%), Positives = 169/335 (50%), Gaps = 22/335 (6%)
Query: 10 NASWGAPANASGCPGCGANASDGPVPSPRAVDAWLVPLFFAALMLLGLVGNSLVIYVICR 69
N S +P ++ P NAS G P + +V L+ A + + GL+GN LV+YVI R
Sbjct: 21 NLSLLSPNHSLLPPHLLLNASHGAF-LPLGLKVTIVGLYLA-VCVGGLLGNCLVMYVILR 78
Query: 70 HKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNYIQQVSVQAT 129
H M+T TN YI NLA D T +L +PF L W G+ +CK V I ++ +
Sbjct: 79 HTKMKTATNIYIFNLALAD-TLVLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTS 137
Query: 130 CATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAPVLALHRLS-PGPR 188
TLTAMSVDR+ P+RAL RT A AV+++IW ++ V PV +
Sbjct: 138 TFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEE 197
Query: 189 AYCSEAFPSRA--LERAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPAPADSALQ 246
C P+ FA+ L +++P+L CY+ M+R L V + L
Sbjct: 198 IECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIRRLRGVRL--------LS 249
Query: 247 GQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYAAYALKT 306
G +R +++RLV VV +F CW P+Q+F++ Q LG P S A A+
Sbjct: 250 GSREKDRN---LRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGV----QPSSETAVAILR 302
Query: 307 WAHCMSYSNSALNPLLYAFLGSHFRQAFRRVCPCA 341
+ + Y NS LNP+LYAFL +F+ FR+ C CA
Sbjct: 303 FCTALGYVNSCLNPILYAFLDENFKACFRKFC-CA 336
>gi|33286424 opiate receptor-like 1 [Homo sapiens]
Length = 370
Score = 163 bits (413), Expect = 2e-40
Identities = 118/335 (35%), Positives = 169/335 (50%), Gaps = 22/335 (6%)
Query: 10 NASWGAPANASGCPGCGANASDGPVPSPRAVDAWLVPLFFAALMLLGLVGNSLVIYVICR 69
N S +P ++ P NAS G P + +V L+ A + + GL+GN LV+YVI R
Sbjct: 21 NLSLLSPNHSLLPPHLLLNASHGAF-LPLGLKVTIVGLYLA-VCVGGLLGNCLVMYVILR 78
Query: 70 HKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNYIQQVSVQAT 129
H M+T TN YI NLA D T +L +PF L W G+ +CK V I ++ +
Sbjct: 79 HTKMKTATNIYIFNLALAD-TLVLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTS 137
Query: 130 CATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAPVLALHRLS-PGPR 188
TLTAMSVDR+ P+RAL RT A AV+++IW ++ V PV +
Sbjct: 138 TFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEE 197
Query: 189 AYCSEAFPSRA--LERAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPAPADSALQ 246
C P+ FA+ L +++P+L CY+ M+R L V + L
Sbjct: 198 IECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIRRLRGVRL--------LS 249
Query: 247 GQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYAAYALKT 306
G +R +++RLV VV +F CW P+Q+F++ Q LG P S A A+
Sbjct: 250 GSREKDRN---LRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGV----QPSSETAVAILR 302
Query: 307 WAHCMSYSNSALNPLLYAFLGSHFRQAFRRVCPCA 341
+ + Y NS LNP+LYAFL +F+ FR+ C CA
Sbjct: 303 FCTALGYVNSCLNPILYAFLDENFKACFRKFC-CA 336
>gi|4557857 somatostatin receptor 1 [Homo sapiens]
Length = 391
Score = 159 bits (403), Expect = 3e-39
Identities = 108/347 (31%), Positives = 168/347 (48%), Gaps = 35/347 (10%)
Query: 6 TSGPNASWGAPANASGCPGCGANASDGPVPSPRAVD-----------AWLVPLFFAALML 54
+S P+ S G+ G G GA A+DG R A L+ ++ + L
Sbjct: 11 SSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCL 70
Query: 55 LGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFM 114
+GL GNS+VIYVI R+ M+T TN YI NLA D L+ VPF L W G +
Sbjct: 71 VGLCGNSMVIYVILRYAKMKTATNIYILNLAIAD-ELLMLSVPFLVTSTLLRHWPFGALL 129
Query: 115 CKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVS 174
C+ V + V++ + LT +SVDR+ V P++A R P +A V+L +WV S V
Sbjct: 130 CRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVI 189
Query: 175 APVLALHRLSPGP--RAYCSEAFPSRALE--RAFALYNLLALYLLPLLATCACYAAMLRH 230
P++ R + C+ P A F LY L +LLP+ A C CY ++
Sbjct: 190 LPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAK 249
Query: 231 LGRVAVRPAPADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGP 290
+ VA++ + Q + +ER K++ +V VV++F CW P F V+Q +
Sbjct: 250 MRMVALK-----AGWQQRKRSER------KITLMVMMVVMVFVICWMP---FYVVQLVNV 295
Query: 291 AGSWHPRSYAAYALKTWAHCMSYSNSALNPLLYAFLGSHFRQAFRRV 337
+ + ++ + Y+NS NP+LY FL +F+++F+R+
Sbjct: 296 FAEQDDATVSQLSV-----ILGYANSCANPILYGFLSDNFKRSFQRI 337
>gi|39725940 opioid receptor, kappa 1 [Homo sapiens]
Length = 380
Score = 159 bits (401), Expect = 5e-39
Identities = 108/340 (31%), Positives = 171/340 (50%), Gaps = 28/340 (8%)
Query: 9 PNASWGAPANASGCPGCGANASDGPVPSPRAVDAW--LVPLFFAALMLLGLVGNSLVIYV 66
PN+S P A A + D + A ++ ++ + ++GLVGNSLV++V
Sbjct: 24 PNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFV 83
Query: 67 ICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNYIQQVSV 126
I R+ M+T TN YI NLA D + +PF + +Y + W GD +CK V I ++
Sbjct: 84 IIRYTKMKTATNIYIFNLALADA-LVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNM 142
Query: 127 QATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWV--GSAAVSAPVLALHRLS 184
+ TLT MSVDR+ P++AL RTP A +++ IW+ S +SA VL ++
Sbjct: 143 FTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVR 202
Query: 185 PGPRAY-CSEAFPSRAL---ERAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPAP 240
CS FP + + + +++P+L CY M+ L V +
Sbjct: 203 EDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRL---- 258
Query: 241 ADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYA 300
L G +R +++RLV VV +F CW PI +F++++ALG S++
Sbjct: 259 ----LSGSREKDRN---LRRITRLVLVVVAVFVVCWTPIHIFILVEALGST------SHS 305
Query: 301 AYALKTWAHC--MSYSNSALNPLLYAFLGSHFRQAFRRVC 338
AL ++ C + Y+NS+LNP+LYAFL +F++ FR C
Sbjct: 306 TAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFC 345
>gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]
Length = 493
Score = 155 bits (392), Expect = 6e-38
Identities = 107/353 (30%), Positives = 170/353 (48%), Gaps = 38/353 (10%)
Query: 5 ATSGPNASWGAPANASGCPG-----CGANASD--------GPVPSPRAVDAWLVPLFFAA 51
++ P S G+ N S G CG N +D P SP + A + ++
Sbjct: 113 SSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSI 172
Query: 52 LMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLG 111
+ ++GL GN LV+YVI R+ M+T TN YI NLA D +PF ++ Y + W G
Sbjct: 173 VCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADA-LATSTLPFQSVNYLMGTWPFG 231
Query: 112 DFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSA 171
+CK V I ++ + TL MSVDR+ P++AL RTPR A +++ W+ S+
Sbjct: 232 TILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSS 291
Query: 172 AVSAPV--LALHRLSPGPRAYCSEAF--PSRALERAFALYNLLALYLLPLLATCACYAAM 227
A+ PV +A + G C+ F P+ E + + +++P+L CY M
Sbjct: 292 AIGLPVMFMATTKYRQG-SIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLM 350
Query: 228 LRHLGRVAVRPAPADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQA 287
+ L V + L G +R +++R+V VV +F CW PI ++++++A
Sbjct: 351 ILRLKSVRM--------LSGSKEKDRN---LRRITRMVLVVVAVFIVCWTPIHIYVIIKA 399
Query: 288 LGPAGSWHPRSYAAYALKTWAHC--MSYSNSALNPLLYAFLGSHFRQAFRRVC 338
L + +W C + Y+NS LNP+LYAFL +F++ FR C
Sbjct: 400 LVTIPE------TTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFC 446
>gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]
Length = 400
Score = 155 bits (392), Expect = 6e-38
Identities = 107/353 (30%), Positives = 170/353 (48%), Gaps = 38/353 (10%)
Query: 5 ATSGPNASWGAPANASGCPG-----CGANASD--------GPVPSPRAVDAWLVPLFFAA 51
++ P S G+ N S G CG N +D P SP + A + ++
Sbjct: 20 SSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSI 79
Query: 52 LMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLG 111
+ ++GL GN LV+YVI R+ M+T TN YI NLA D +PF ++ Y + W G
Sbjct: 80 VCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADA-LATSTLPFQSVNYLMGTWPFG 138
Query: 112 DFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSA 171
+CK V I ++ + TL MSVDR+ P++AL RTPR A +++ W+ S+
Sbjct: 139 TILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSS 198
Query: 172 AVSAPV--LALHRLSPGPRAYCSEAF--PSRALERAFALYNLLALYLLPLLATCACYAAM 227
A+ PV +A + G C+ F P+ E + + +++P+L CY M
Sbjct: 199 AIGLPVMFMATTKYRQG-SIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLM 257
Query: 228 LRHLGRVAVRPAPADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQA 287
+ L V + L G +R +++R+V VV +F CW PI ++++++A
Sbjct: 258 ILRLKSVRM--------LSGSKEKDRN---LRRITRMVLVVVAVFIVCWTPIHIYVIIKA 306
Query: 288 LGPAGSWHPRSYAAYALKTWAHC--MSYSNSALNPLLYAFLGSHFRQAFRRVC 338
L + +W C + Y+NS LNP+LYAFL +F++ FR C
Sbjct: 307 LVTIPE------TTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFC 353
>gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]
Length = 420
Score = 155 bits (392), Expect = 6e-38
Identities = 107/353 (30%), Positives = 170/353 (48%), Gaps = 38/353 (10%)
Query: 5 ATSGPNASWGAPANASGCPG-----CGANASD--------GPVPSPRAVDAWLVPLFFAA 51
++ P S G+ N S G CG N +D P SP + A + ++
Sbjct: 20 SSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSI 79
Query: 52 LMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLG 111
+ ++GL GN LV+YVI R+ M+T TN YI NLA D +PF ++ Y + W G
Sbjct: 80 VCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADA-LATSTLPFQSVNYLMGTWPFG 138
Query: 112 DFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSA 171
+CK V I ++ + TL MSVDR+ P++AL RTPR A +++ W+ S+
Sbjct: 139 TILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSS 198
Query: 172 AVSAPV--LALHRLSPGPRAYCSEAF--PSRALERAFALYNLLALYLLPLLATCACYAAM 227
A+ PV +A + G C+ F P+ E + + +++P+L CY M
Sbjct: 199 AIGLPVMFMATTKYRQG-SIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLM 257
Query: 228 LRHLGRVAVRPAPADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQA 287
+ L V + L G +R +++R+V VV +F CW PI ++++++A
Sbjct: 258 ILRLKSVRM--------LSGSKEKDRN---LRRITRMVLVVVAVFIVCWTPIHIYVIIKA 306
Query: 288 LGPAGSWHPRSYAAYALKTWAHC--MSYSNSALNPLLYAFLGSHFRQAFRRVC 338
L + +W C + Y+NS LNP+LYAFL +F++ FR C
Sbjct: 307 LVTIPE------TTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFC 353
>gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]
Length = 397
Score = 155 bits (392), Expect = 6e-38
Identities = 107/353 (30%), Positives = 170/353 (48%), Gaps = 38/353 (10%)
Query: 5 ATSGPNASWGAPANASGCPG-----CGANASD--------GPVPSPRAVDAWLVPLFFAA 51
++ P S G+ N S G CG N +D P SP + A + ++
Sbjct: 20 SSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSI 79
Query: 52 LMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLG 111
+ ++GL GN LV+YVI R+ M+T TN YI NLA D +PF ++ Y + W G
Sbjct: 80 VCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADA-LATSTLPFQSVNYLMGTWPFG 138
Query: 112 DFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSA 171
+CK V I ++ + TL MSVDR+ P++AL RTPR A +++ W+ S+
Sbjct: 139 TILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSS 198
Query: 172 AVSAPV--LALHRLSPGPRAYCSEAF--PSRALERAFALYNLLALYLLPLLATCACYAAM 227
A+ PV +A + G C+ F P+ E + + +++P+L CY M
Sbjct: 199 AIGLPVMFMATTKYRQG-SIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLM 257
Query: 228 LRHLGRVAVRPAPADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQA 287
+ L V + L G +R +++R+V VV +F CW PI ++++++A
Sbjct: 258 ILRLKSVRM--------LSGSKEKDRN---LRRITRMVLVVVAVFIVCWTPIHIYVIIKA 306
Query: 288 LGPAGSWHPRSYAAYALKTWAHC--MSYSNSALNPLLYAFLGSHFRQAFRRVC 338
L + +W C + Y+NS LNP+LYAFL +F++ FR C
Sbjct: 307 LVTIPE------TTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFC 353
>gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]
Length = 403
Score = 155 bits (392), Expect = 6e-38
Identities = 107/353 (30%), Positives = 170/353 (48%), Gaps = 38/353 (10%)
Query: 5 ATSGPNASWGAPANASGCPG-----CGANASD--------GPVPSPRAVDAWLVPLFFAA 51
++ P S G+ N S G CG N +D P SP + A + ++
Sbjct: 20 SSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSI 79
Query: 52 LMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLG 111
+ ++GL GN LV+YVI R+ M+T TN YI NLA D +PF ++ Y + W G
Sbjct: 80 VCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADA-LATSTLPFQSVNYLMGTWPFG 138
Query: 112 DFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSA 171
+CK V I ++ + TL MSVDR+ P++AL RTPR A +++ W+ S+
Sbjct: 139 TILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSS 198
Query: 172 AVSAPV--LALHRLSPGPRAYCSEAF--PSRALERAFALYNLLALYLLPLLATCACYAAM 227
A+ PV +A + G C+ F P+ E + + +++P+L CY M
Sbjct: 199 AIGLPVMFMATTKYRQG-SIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLM 257
Query: 228 LRHLGRVAVRPAPADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQA 287
+ L V + L G +R +++R+V VV +F CW PI ++++++A
Sbjct: 258 ILRLKSVRM--------LSGSKEKDRN---LRRITRMVLVVVAVFIVCWTPIHIYVIIKA 306
Query: 288 LGPAGSWHPRSYAAYALKTWAHC--MSYSNSALNPLLYAFLGSHFRQAFRRVC 338
L + +W C + Y+NS LNP+LYAFL +F++ FR C
Sbjct: 307 LVTIPE------TTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFC 353
>gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]
Length = 406
Score = 155 bits (392), Expect = 6e-38
Identities = 107/353 (30%), Positives = 170/353 (48%), Gaps = 38/353 (10%)
Query: 5 ATSGPNASWGAPANASGCPG-----CGANASD--------GPVPSPRAVDAWLVPLFFAA 51
++ P S G+ N S G CG N +D P SP + A + ++
Sbjct: 20 SSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSI 79
Query: 52 LMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLG 111
+ ++GL GN LV+YVI R+ M+T TN YI NLA D +PF ++ Y + W G
Sbjct: 80 VCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADA-LATSTLPFQSVNYLMGTWPFG 138
Query: 112 DFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSA 171
+CK V I ++ + TL MSVDR+ P++AL RTPR A +++ W+ S+
Sbjct: 139 TILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSS 198
Query: 172 AVSAPV--LALHRLSPGPRAYCSEAF--PSRALERAFALYNLLALYLLPLLATCACYAAM 227
A+ PV +A + G C+ F P+ E + + +++P+L CY M
Sbjct: 199 AIGLPVMFMATTKYRQG-SIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLM 257
Query: 228 LRHLGRVAVRPAPADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQA 287
+ L V + L G +R +++R+V VV +F CW PI ++++++A
Sbjct: 258 ILRLKSVRM--------LSGSKEKDRN---LRRITRMVLVVVAVFIVCWTPIHIYVIIKA 306
Query: 288 LGPAGSWHPRSYAAYALKTWAHC--MSYSNSALNPLLYAFLGSHFRQAFRRVC 338
L + +W C + Y+NS LNP+LYAFL +F++ FR C
Sbjct: 307 LVTIPE------TTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFC 353
>gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens]
Length = 392
Score = 155 bits (392), Expect = 6e-38
Identities = 107/353 (30%), Positives = 170/353 (48%), Gaps = 38/353 (10%)
Query: 5 ATSGPNASWGAPANASGCPG-----CGANASD--------GPVPSPRAVDAWLVPLFFAA 51
++ P S G+ N S G CG N +D P SP + A + ++
Sbjct: 20 SSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSI 79
Query: 52 LMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLG 111
+ ++GL GN LV+YVI R+ M+T TN YI NLA D +PF ++ Y + W G
Sbjct: 80 VCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADA-LATSTLPFQSVNYLMGTWPFG 138
Query: 112 DFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSA 171
+CK V I ++ + TL MSVDR+ P++AL RTPR A +++ W+ S+
Sbjct: 139 TILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSS 198
Query: 172 AVSAPV--LALHRLSPGPRAYCSEAF--PSRALERAFALYNLLALYLLPLLATCACYAAM 227
A+ PV +A + G C+ F P+ E + + +++P+L CY M
Sbjct: 199 AIGLPVMFMATTKYRQG-SIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLM 257
Query: 228 LRHLGRVAVRPAPADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQA 287
+ L V + L G +R +++R+V VV +F CW PI ++++++A
Sbjct: 258 ILRLKSVRM--------LSGSKEKDRN---LRRITRMVLVVVAVFIVCWTPIHIYVIIKA 306
Query: 288 LGPAGSWHPRSYAAYALKTWAHC--MSYSNSALNPLLYAFLGSHFRQAFRRVC 338
L + +W C + Y+NS LNP+LYAFL +F++ FR C
Sbjct: 307 LVTIPE------TTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFC 353
>gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens]
Length = 389
Score = 155 bits (392), Expect = 6e-38
Identities = 107/353 (30%), Positives = 170/353 (48%), Gaps = 38/353 (10%)
Query: 5 ATSGPNASWGAPANASGCPG-----CGANASD--------GPVPSPRAVDAWLVPLFFAA 51
++ P S G+ N S G CG N +D P SP + A + ++
Sbjct: 20 SSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSI 79
Query: 52 LMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLG 111
+ ++GL GN LV+YVI R+ M+T TN YI NLA D +PF ++ Y + W G
Sbjct: 80 VCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADA-LATSTLPFQSVNYLMGTWPFG 138
Query: 112 DFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSA 171
+CK V I ++ + TL MSVDR+ P++AL RTPR A +++ W+ S+
Sbjct: 139 TILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSS 198
Query: 172 AVSAPV--LALHRLSPGPRAYCSEAF--PSRALERAFALYNLLALYLLPLLATCACYAAM 227
A+ PV +A + G C+ F P+ E + + +++P+L CY M
Sbjct: 199 AIGLPVMFMATTKYRQG-SIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLM 257
Query: 228 LRHLGRVAVRPAPADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQA 287
+ L V + L G +R +++R+V VV +F CW PI ++++++A
Sbjct: 258 ILRLKSVRM--------LSGSKEKDRN---LRRITRMVLVVVAVFIVCWTPIHIYVIIKA 306
Query: 288 LGPAGSWHPRSYAAYALKTWAHC--MSYSNSALNPLLYAFLGSHFRQAFRRVC 338
L + +W C + Y+NS LNP+LYAFL +F++ FR C
Sbjct: 307 LVTIPE------TTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFC 353
>gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens]
Length = 418
Score = 155 bits (392), Expect = 6e-38
Identities = 107/353 (30%), Positives = 170/353 (48%), Gaps = 38/353 (10%)
Query: 5 ATSGPNASWGAPANASGCPG-----CGANASD--------GPVPSPRAVDAWLVPLFFAA 51
++ P S G+ N S G CG N +D P SP + A + ++
Sbjct: 20 SSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSI 79
Query: 52 LMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLG 111
+ ++GL GN LV+YVI R+ M+T TN YI NLA D +PF ++ Y + W G
Sbjct: 80 VCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADA-LATSTLPFQSVNYLMGTWPFG 138
Query: 112 DFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSA 171
+CK V I ++ + TL MSVDR+ P++AL RTPR A +++ W+ S+
Sbjct: 139 TILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSS 198
Query: 172 AVSAPV--LALHRLSPGPRAYCSEAF--PSRALERAFALYNLLALYLLPLLATCACYAAM 227
A+ PV +A + G C+ F P+ E + + +++P+L CY M
Sbjct: 199 AIGLPVMFMATTKYRQG-SIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLM 257
Query: 228 LRHLGRVAVRPAPADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQA 287
+ L V + L G +R +++R+V VV +F CW PI ++++++A
Sbjct: 258 ILRLKSVRM--------LSGSKEKDRN---LRRITRMVLVVVAVFIVCWTPIHIYVIIKA 306
Query: 288 LGPAGSWHPRSYAAYALKTWAHC--MSYSNSALNPLLYAFLGSHFRQAFRRVC 338
L + +W C + Y+NS LNP+LYAFL +F++ FR C
Sbjct: 307 LVTIPE------TTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFC 353
>gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens]
Length = 446
Score = 155 bits (392), Expect = 6e-38
Identities = 107/353 (30%), Positives = 170/353 (48%), Gaps = 38/353 (10%)
Query: 5 ATSGPNASWGAPANASGCPG-----CGANASD--------GPVPSPRAVDAWLVPLFFAA 51
++ P S G+ N S G CG N +D P SP + A + ++
Sbjct: 20 SSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSI 79
Query: 52 LMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLG 111
+ ++GL GN LV+YVI R+ M+T TN YI NLA D +PF ++ Y + W G
Sbjct: 80 VCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADA-LATSTLPFQSVNYLMGTWPFG 138
Query: 112 DFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSA 171
+CK V I ++ + TL MSVDR+ P++AL RTPR A +++ W+ S+
Sbjct: 139 TILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSS 198
Query: 172 AVSAPV--LALHRLSPGPRAYCSEAF--PSRALERAFALYNLLALYLLPLLATCACYAAM 227
A+ PV +A + G C+ F P+ E + + +++P+L CY M
Sbjct: 199 AIGLPVMFMATTKYRQG-SIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLM 257
Query: 228 LRHLGRVAVRPAPADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQA 287
+ L V + L G +R +++R+V VV +F CW PI ++++++A
Sbjct: 258 ILRLKSVRM--------LSGSKEKDRN---LRRITRMVLVVVAVFIVCWTPIHIYVIIKA 306
Query: 288 LGPAGSWHPRSYAAYALKTWAHC--MSYSNSALNPLLYAFLGSHFRQAFRRVC 338
L + +W C + Y+NS LNP+LYAFL +F++ FR C
Sbjct: 307 LVTIPE------TTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFC 353
>gi|4758474 G protein-coupled receptor 10 [Homo sapiens]
Length = 370
Score = 152 bits (383), Expect = 7e-37
Identities = 107/310 (34%), Positives = 164/310 (52%), Gaps = 24/310 (7%)
Query: 44 LVPLFFAALMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFT-ALL 102
L+ L ++ ++++GLVGN L++ VI R + + VTNF I NLA +DV CVP T A
Sbjct: 62 LIVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPLTLAYA 121
Query: 103 YPLPGWVLGDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAV 162
+ GWV G +C V ++Q V+V + TLT ++VDR+ V V PLR R + RL+
Sbjct: 122 FEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLR--RRISLRLSAYA 179
Query: 163 SLSIWVGSAAVSAPVLALH----RLSPGPRAYCSEAFPSRALERAFALYNLLAL-YLLPL 217
L+IW SA ++ P A+H L P C E + S+ +R + LL + YLLPL
Sbjct: 180 VLAIWALSAVLALPA-AVHTYHVELKPHDVRLCEEFWGSQERQRQLYAWGLLLVTYLLPL 238
Query: 218 LATCACYAAMLRHLGRVAVRPAPADSALQGQVLAERAGAVRAKVSR---LVAAVVLLFAA 274
L Y RV+V+ + + G V +A RA+ R L+ VV++FA
Sbjct: 239 LVILLSYV-------RVSVK--LRNRVVPGCVTQSQADWDRARRRRTFCLLVVVVVVFAV 289
Query: 275 CWGPIQLFLVLQALGPAGSWHPRSYAAYALKTWAHCMSYSNSALNPLLYAFLGSHFRQAF 334
CW P+ +F +L+ L P YA ++ H ++ S++ NP +YA+L FR+
Sbjct: 290 CWLPLHVFNLLRDLDPHAI---DPYAFGLVQLLCHWLAMSSACYNPFIYAWLHDSFREEL 346
Query: 335 RRVCPCAPRR 344
R++ PR+
Sbjct: 347 RKLLVAWPRK 356
>gi|4557859 somatostatin receptor 2 [Homo sapiens]
Length = 369
Score = 145 bits (365), Expect = 8e-35
Identities = 93/298 (31%), Positives = 156/298 (52%), Gaps = 20/298 (6%)
Query: 44 LVPLFFAALMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLY 103
++ + + ++GL GN+LVIYVI R+ M+T+TN YI NLA D F+L +PF A+
Sbjct: 45 VLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLG-LPFLAMQV 103
Query: 104 PLPGWVLGDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVS 163
L W G +C+ V + ++ + LT MS+DR+ V P+++ R PR A ++
Sbjct: 104 ALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMIT 163
Query: 164 LSIWVGSAAVSAPVL--ALHRLSPGPRAYCSEAFP--SRALERAFALYNLLALYLLPLLA 219
+++W S V P++ A R + R+ C+ +P S A F +Y + +L+PL
Sbjct: 164 MAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTI 223
Query: 220 TCACYAAMLRHLGRVAVRPAPADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPI 279
C CY ++ + +R V + + KV+R+V+ VV +F CW P
Sbjct: 224 ICLCYLFIIIKVKSSGIR-----------VGSSKRKKSEKKVTRMVSIVVAVFIFCWLPF 272
Query: 280 QLFLVLQALGPAGSWHPRSYAAYALKTWAHCMSYSNSALNPLLYAFLGSHFRQAFRRV 337
+F V ++ A S P A + + ++Y+NS NP+LYAFL +F+++F+ V
Sbjct: 273 YIFNV-SSVSMAISPTP---ALKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNV 326
>gi|53828924 G protein-coupled receptor 7 [Homo sapiens]
Length = 328
Score = 145 bits (365), Expect = 8e-35
Identities = 116/341 (34%), Positives = 164/341 (48%), Gaps = 29/341 (8%)
Query: 10 NASWGAP--ANASG---CPGCGANASDGPVPSPRAVDAWLVPLFFAALMLLGLVGNSLVI 64
NAS+ P ANASG C ++ P+P+P AV VP+ +A + +GL GNS V+
Sbjct: 3 NASFSEPWPANASGPDPALSCSNASTLAPLPAPLAV---AVPVVYAVICAVGLAGNSAVL 59
Query: 65 YVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNYIQQV 124
YV+ R M+TVTN +I NLA D F L +P + L W G+ MCK + I Q
Sbjct: 60 YVLLRAPRMKTVTNLFILNLAIADELFTL-VLPINIADFLLRQWPFGELMCKLIVAIDQY 118
Query: 125 SVQATCATLTAMSVDRWYVTVFPL--RALHRRTPRLALAVSLSIWVGSAAVSAPVLALHR 182
+ ++ LT MS DR+ V + R + RT A AVSL++W V P R
Sbjct: 119 NTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFAR 178
Query: 183 LSPGP-RAYCSEAFPSRAL--ERAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPA 239
L R C FP RA LY L+ + +P+ C Y +L L A+R
Sbjct: 179 LDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLH--AMRLD 236
Query: 240 PADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSY 299
AL ERA + +V+ LV A++ + CW P L V+ P++
Sbjct: 237 SHAKAL------ERA---KKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDL----PQTP 283
Query: 300 AAYALKTWAHCMSYSNSALNPLLYAFLGSHFRQAFRRVCPC 340
A+ + +SY+NS LNP LYAFL + FR+ R++ C
Sbjct: 284 LVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITC 324
>gi|222080095 orexin receptor 1 [Homo sapiens]
Length = 425
Score = 144 bits (362), Expect = 2e-34
Identities = 100/334 (29%), Positives = 153/334 (45%), Gaps = 41/334 (12%)
Query: 43 WLVPLFFAALMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALL 102
W++ + A+ ++ LVGN+LV + R+ MRTVTN++I NL+ DV C+P + L+
Sbjct: 47 WVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLV 106
Query: 103 YPLPGWVLGDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAV 162
W+ G +CK + Y+Q VSV TL+ +++DRWY PL L + T R A
Sbjct: 107 DITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPL--LFKSTARRARGS 164
Query: 163 SLSIWVGSAAVSAPVLA-------LHRLSPGPRAY--CSEAFPSRALERAFALYNLLALY 213
L IW S A+ P A L L+ R + C E + + + + Y
Sbjct: 165 ILGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTY 224
Query: 214 LLPLLATCACYAAMLRHL-GR--------------------------VAVRPAPADSALQ 246
L PL Y + R L GR ++ P P A
Sbjct: 225 LAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFL 284
Query: 247 GQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYAAYALKT 306
+V RA R K ++++ V+L+FA C+ PI + VL+ + A YA T
Sbjct: 285 AEVKQMRA---RRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFT 341
Query: 307 WAHCMSYSNSALNPLLYAFLGSHFRQAFRRVCPC 340
++H + Y+NSA NP++Y FL FR+ F+ C
Sbjct: 342 FSHWLVYANSAANPIIYNFLSGKFREQFKAAFSC 375
>gi|30581164 neuropeptides B/W receptor 2 [Homo sapiens]
Length = 333
Score = 141 bits (355), Expect = 1e-33
Identities = 103/331 (31%), Positives = 155/331 (46%), Gaps = 27/331 (8%)
Query: 17 ANASGCPGCGANAS-DGPVPSPRAVDAWLVPLFFAALMLLGLVGNSLVIYVICRHKPMRT 75
AN S G G NA+ P+P L+P ++ + +GL GN+ VI VI R M+T
Sbjct: 23 ANVSQDNGTGHNATFSEPLPFLYV----LLPAVYSGICAVGLTGNTAVILVILRAPKMKT 78
Query: 76 VTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNYIQQVSVQATCATLTA 135
VTN +I NLA D F L +P + L W G+ +CK V + ++ ++ L
Sbjct: 79 VTNVFILNLAVADGLFTL-VLPVNIAEHLLQYWPFGELLCKLVLAVDHYNIFSSIYFLAV 137
Query: 136 MSVDRWYVTVFPLRALHR--RTPRLALAVSLSIWVGSAAVSAPVLALHRLSPG----PRA 189
MSVDR+ V + +R+ H RT R A SL +W+G + P + + P
Sbjct: 138 MSVDRYLVVLATVRSRHMPWRTYRGAKVASLCVWLGVTVLVLPFFSFAGVYSNELQVPSC 197
Query: 190 YCSEAFPSRALERAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPAPADSALQGQV 249
S +P + +A +Y L+ ++LP+ C Y +LR L V +R
Sbjct: 198 GLSFPWPEQVWFKASRVYTLVLGFVLPVCTICVLYTDLLRRLRAVRLRSG---------- 247
Query: 250 LAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYAAYALKTWAH 309
A+ G R KV+ LV V+ + CW P L V+ P++ ++
Sbjct: 248 -AKALGKARRKVTVLVLVVLAVCLLCWTPFHLASVVALTTDL----PQTPLVISMSYVIT 302
Query: 310 CMSYSNSALNPLLYAFLGSHFRQAFRRVCPC 340
+SY+NS LNP LYAFL +FR+ FR + C
Sbjct: 303 SLSYANSCLNPFLYAFLDDNFRKNFRSILRC 333
>gi|222080109 orexin receptor 2 [Homo sapiens]
Length = 444
Score = 138 bits (347), Expect = 1e-32
Identities = 92/332 (27%), Positives = 153/332 (46%), Gaps = 39/332 (11%)
Query: 43 WLVPLFFAALMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALL 102
W++ + + ++ L+GN LV + ++ MRTVTN++I NL+ DV + C+P T ++
Sbjct: 55 WVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVV 114
Query: 103 YPLPGWVLGDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAV 162
W G +CK + Y+Q VSV + TL+ +++DRWY PL + + T + A
Sbjct: 115 DITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPL--MFKSTAKRARNS 172
Query: 163 SLSIWVGSAAVSAP---VLALHRLSPGPR------AYCSEAFPSRALERAFALYNLLALY 213
+ IW+ S + P V+ + PG C E + + + + L Y
Sbjct: 173 IVIIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTY 232
Query: 214 LLPLLATCACYAAMLRHLGRVAVRPAPADSAL----------------QGQVLAERAGAV 257
+ PL C A L+ ++ R P S++ GQ R AV
Sbjct: 233 MAPL---CLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAV 289
Query: 258 ---------RAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYAAYALKTWA 308
R K +R++ V+L+FA C+ PI + VL+ + + YA T++
Sbjct: 290 AAEIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFS 349
Query: 309 HCMSYSNSALNPLLYAFLGSHFRQAFRRVCPC 340
H + Y+NSA NP++Y FL FR+ F+ C
Sbjct: 350 HWLVYANSAANPIIYNFLSGKFREEFKAAFSC 381
>gi|11545887 neuropeptide FF receptor 1 [Homo sapiens]
Length = 430
Score = 138 bits (347), Expect = 1e-32
Identities = 104/351 (29%), Positives = 168/351 (47%), Gaps = 29/351 (8%)
Query: 9 PNASWGAPANASGCPGCGA-NASDGPVPSPRAVDAWLVPLFFAALMLLGLVGNSLVIYVI 67
PN+SW N + A N + + A + + +A + LL +VGN+LV +++
Sbjct: 9 PNSSWPLSQNGTNTEATPATNLTFSSYYQHTSPVAAMFIVAYALIFLLCMVGNTLVCFIV 68
Query: 68 CRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNYIQQVSVQ 127
+++ M TVTN +I NLA +D+ + C+P T + + GW + CK +Q +SV
Sbjct: 69 LKNRHMHTVTNMFILNLAVSDLLVGIFCMPTTLVDNLITGWPFDNATCKMSGLVQGMSVS 128
Query: 128 ATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAV---SAPVLALHR-- 182
A+ TL A++V+R+ V P R + T R AL IW + + SA L + R
Sbjct: 129 ASVFTLVAIAVERFRCIVHPFR--EKLTLRKALVTIAVIWALALLIMCPSAVTLTVTREE 186
Query: 183 ----LSPGPRAY----CSEAFPSRALERAFALYNLLALYLLPLLATCACYAAMLRHLGRV 234
+ R+Y C EA+P + + R + +YL PL YA + R L +
Sbjct: 187 HHFMVDARNRSYPLYSCWEAWPEKGMRRVYTTVLFSHIYLAPLALIVVMYARIARKLCQ- 245
Query: 235 AVRPAPADSALQGQVLAE-RAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGS 293
A PAP G+ A+ RA RA+V ++ V L F W P+ L+L G +
Sbjct: 246 APGPAPG-----GEEAADPRASRRRARVVHMLVMVALFFTLSWLPLWALLLLIDYGQLSA 300
Query: 294 WHPRSYAAYALKTWAHCMSYSNSALNPLLYAFLGSHFRQAFR-----RVCP 339
YA +AH +++ NS+ NP++Y + +FR+ F+ R+CP
Sbjct: 301 PQLHLVTVYAF-PFAHWLAFFNSSANPIIYGYFNENFRRGFQAAFRARLCP 350
>gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens]
Length = 420
Score = 132 bits (333), Expect = 4e-31
Identities = 85/313 (27%), Positives = 156/313 (49%), Gaps = 23/313 (7%)
Query: 37 PRAVDAWLVPLFFAALMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCV 96
P+ +++ F + L ++GN++V +++ R+K M TVTN +I NLA +D+ + C+
Sbjct: 42 PQVAAIFIISYFL--IFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCM 99
Query: 97 PFTALLYPLPGWVLGDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTP 156
P T L + GW G+ MCK +Q +SV A+ TL A++VDR+ V+P + + T
Sbjct: 100 PITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKP--KLTI 157
Query: 157 RLALAVSLSIWVGSAAVSAP-VLALH---------RLS----PGPRAYCSEAFPSRALER 202
+ A + + IWV + + +P + LH RL+ P +C E +P++ + +
Sbjct: 158 KTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRK 217
Query: 203 AFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPAPADSALQGQVLAERAGAVRAKVS 262
+ +YL PL Y + L R AV + Q V++ + + K+
Sbjct: 218 IYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRK----KQKII 273
Query: 263 RLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYAAYALKTWAHCMSYSNSALNPLL 322
+++ V LLF W P+ ++L + Y + +AH +++ NS++NP++
Sbjct: 274 KMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIY-IYPFAHWLAFGNSSVNPII 332
Query: 323 YAFLGSHFRQAFR 335
Y F +FR+ F+
Sbjct: 333 YGFFNENFRRGFQ 345
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.137 0.446
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,460,804
Number of Sequences: 37866
Number of extensions: 785734
Number of successful extensions: 7020
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 445
Number of HSP's successfully gapped in prelim test: 268
Number of HSP's that attempted gapping in prelim test: 5419
Number of HSP's gapped (non-prelim): 1017
length of query: 398
length of database: 18,247,518
effective HSP length: 104
effective length of query: 294
effective length of database: 14,309,454
effective search space: 4206979476
effective search space used: 4206979476
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.