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Search of human proteins with 62000698
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62000698 transmembrane protein 225 [Homo sapiens]
(225 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62000698 transmembrane protein 225 [Homo sapiens] 460 e-130
gi|239754660 PREDICTED: hypothetical protein [Homo sapiens] 42 3e-04
gi|239749194 PREDICTED: hypothetical protein XP_002346946 [Homo ... 42 3e-04
gi|239743274 PREDICTED: hypothetical protein XP_002342783 [Homo ... 42 3e-04
gi|239508955 PREDICTED: hypothetical protein [Homo sapiens] 42 3e-04
gi|22748765 claudin domain containing 2 [Homo sapiens] 37 0.018
gi|21361975 voltage-dependent calcium channel gamma-7 subunit [H... 33 0.20
gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo s... 30 1.3
gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo s... 30 1.3
gi|93102367 ral guanine nucleotide dissociation stimulator-like ... 30 1.7
gi|122937323 transmembrane protein 202 [Homo sapiens] 29 2.8
gi|22027551 voltage-dependent calcium channel gamma-5 subunit is... 28 4.8
gi|31083315 G protein-coupled receptor 45 [Homo sapiens] 28 6.3
gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B ... 28 6.3
gi|122937309 leucine rich repeat containing 4B [Homo sapiens] 28 6.3
gi|24497499 solute carrier family 22 member 8 [Homo sapiens] 28 8.3
>gi|62000698 transmembrane protein 225 [Homo sapiens]
Length = 225
Score = 460 bits (1184), Expect = e-130
Identities = 225/225 (100%), Positives = 225/225 (100%)
Query: 1 MVHVSNRSIQGMNILFSSWAVVLMVMGITLDKWVELISEDERAKMNHSPWMMCCPALWPE 60
MVHVSNRSIQGMNILFSSWAVVLMVMGITLDKWVELISEDERAKMNHSPWMMCCPALWPE
Sbjct: 1 MVHVSNRSIQGMNILFSSWAVVLMVMGITLDKWVELISEDERAKMNHSPWMMCCPALWPE 60
Query: 61 DDLKVVRIMMTSSLGLSFLLNLILGMKFTYLIPQNKYIQLFTTILSFFSGISLLWALILY 120
DDLKVVRIMMTSSLGLSFLLNLILGMKFTYLIPQNKYIQLFTTILSFFSGISLLWALILY
Sbjct: 61 DDLKVVRIMMTSSLGLSFLLNLILGMKFTYLIPQNKYIQLFTTILSFFSGISLLWALILY 120
Query: 121 HNKLKQGQSMHFSNYRITWIMYTAYLNVFFLSVCGVLSLLECKLSTSSCTCLNIHKSDNE 180
HNKLKQGQSMHFSNYRITWIMYTAYLNVFFLSVCGVLSLLECKLSTSSCTCLNIHKSDNE
Sbjct: 121 HNKLKQGQSMHFSNYRITWIMYTAYLNVFFLSVCGVLSLLECKLSTSSCTCLNIHKSDNE 180
Query: 181 CKESENSIEDISLPECTAMPRSIVRAHTVNSLNKKVQTRHVTWAL 225
CKESENSIEDISLPECTAMPRSIVRAHTVNSLNKKVQTRHVTWAL
Sbjct: 181 CKESENSIEDISLPECTAMPRSIVRAHTVNSLNKKVQTRHVTWAL 225
>gi|239754660 PREDICTED: hypothetical protein [Homo sapiens]
Length = 221
Score = 42.4 bits (98), Expect = 3e-04
Identities = 41/209 (19%), Positives = 82/209 (39%), Gaps = 19/209 (9%)
Query: 18 SWAVV--------LMVMGITLDK-WVELISEDERAKMNHSPWMMCCPA-LWPEDDLKVV- 66
SWA+V L+++ +++ WV L +E+ + C A W L +
Sbjct: 13 SWAIVPALTSLGYLIILVVSIFPFWVRLTNEESHEVFFSGLFENCFNAKCWKPRPLSIYI 72
Query: 67 ---RIMMTSSLGLSFLLNLILGMKFTYLIPQNKYIQLFTTILSFFSGISLLWALILYHNK 123
R+ + S++ L+F+ I+ + P+ +SFF+G AL+L+ +
Sbjct: 73 ILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGACAFLALVLHALE 132
Query: 124 LKQ-GQSMHFSNYRITWIMYTAYLNVFFLSVCGVLSLLECKLSTSSCTCLNIHKSDNECK 182
+K + + + W Y +F V G + C + C C ++ + +
Sbjct: 133 IKALRMKLGPLQFSVLWPYYVLGFGIFLFIVAGTI----CLIQEMVCPCWHLLSTSQSME 188
Query: 183 ESENSIEDISLPECTAMPRSIVRAHTVNS 211
E S+ +L P S+ + V +
Sbjct: 189 EDHGSLYLDNLESLGGEPSSVQKETQVTA 217
>gi|239749194 PREDICTED: hypothetical protein XP_002346946 [Homo
sapiens]
Length = 221
Score = 42.4 bits (98), Expect = 3e-04
Identities = 41/209 (19%), Positives = 82/209 (39%), Gaps = 19/209 (9%)
Query: 18 SWAVV--------LMVMGITLDK-WVELISEDERAKMNHSPWMMCCPA-LWPEDDLKVV- 66
SWA+V L+++ +++ WV L +E+ + C A W L +
Sbjct: 13 SWAIVPALTSLGYLIILVVSIFPFWVRLTNEESHEVFFSGLFENCFNAKCWKPRPLSIYI 72
Query: 67 ---RIMMTSSLGLSFLLNLILGMKFTYLIPQNKYIQLFTTILSFFSGISLLWALILYHNK 123
R+ + S++ L+F+ I+ + P+ +SFF+G AL+L+ +
Sbjct: 73 ILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGACAFLALVLHALE 132
Query: 124 LKQ-GQSMHFSNYRITWIMYTAYLNVFFLSVCGVLSLLECKLSTSSCTCLNIHKSDNECK 182
+K + + + W Y +F V G + C + C C ++ + +
Sbjct: 133 IKALRMKLGPLQFSVLWPYYVLGFGIFLFIVAGTI----CLIQEMVCPCWHLLSTSQSME 188
Query: 183 ESENSIEDISLPECTAMPRSIVRAHTVNS 211
E S+ +L P S+ + V +
Sbjct: 189 EDHGSLYLDNLESLGGEPSSVQKETQVTA 217
>gi|239743274 PREDICTED: hypothetical protein XP_002342783 [Homo
sapiens]
Length = 221
Score = 42.4 bits (98), Expect = 3e-04
Identities = 41/209 (19%), Positives = 82/209 (39%), Gaps = 19/209 (9%)
Query: 18 SWAVV--------LMVMGITLDK-WVELISEDERAKMNHSPWMMCCPA-LWPEDDLKVV- 66
SWA+V L+++ +++ WV L +E+ + C A W L +
Sbjct: 13 SWAIVPALTSLGYLIILVVSIFPFWVRLTNEESHEVFFSGLFENCFNAKCWKPRPLSIYI 72
Query: 67 ---RIMMTSSLGLSFLLNLILGMKFTYLIPQNKYIQLFTTILSFFSGISLLWALILYHNK 123
R+ + S++ L+F+ I+ + P+ +SFF+G AL+L+ +
Sbjct: 73 ILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGACAFLALVLHALE 132
Query: 124 LKQ-GQSMHFSNYRITWIMYTAYLNVFFLSVCGVLSLLECKLSTSSCTCLNIHKSDNECK 182
+K + + + W Y +F V G + C + C C ++ + +
Sbjct: 133 IKALRMKLGPLQFSVLWPYYVLGFGIFLFIVAGTI----CLIQEMVCPCWHLLSTSQSME 188
Query: 183 ESENSIEDISLPECTAMPRSIVRAHTVNS 211
E S+ +L P S+ + V +
Sbjct: 189 EDHGSLYLDNLESLGGEPSSVQKETQVTA 217
>gi|239508955 PREDICTED: hypothetical protein [Homo sapiens]
Length = 221
Score = 42.4 bits (98), Expect = 3e-04
Identities = 41/209 (19%), Positives = 82/209 (39%), Gaps = 19/209 (9%)
Query: 18 SWAVV--------LMVMGITLDK-WVELISEDERAKMNHSPWMMCCPA-LWPEDDLKVV- 66
SWA+V L+++ +++ WV L +E+ + C A W L +
Sbjct: 13 SWAIVPALTSLGYLIILVVSIFPFWVRLTNEESHEVFFSGLFENCFNAKCWKPRPLSIYI 72
Query: 67 ---RIMMTSSLGLSFLLNLILGMKFTYLIPQNKYIQLFTTILSFFSGISLLWALILYHNK 123
R+ + S++ L+F+ I+ + P+ +SFF+G AL+L+ +
Sbjct: 73 ILGRVFLLSAVFLAFVTTFIMMPFASEFFPRTWKQNFVLACISFFTGACAFLALVLHALE 132
Query: 124 LKQ-GQSMHFSNYRITWIMYTAYLNVFFLSVCGVLSLLECKLSTSSCTCLNIHKSDNECK 182
+K + + + W Y +F V G + C + C C ++ + +
Sbjct: 133 IKALRMKLGPLQFSVLWPYYVLGFGIFLFIVAGTI----CLIQEMVCPCWHLLSTSQSME 188
Query: 183 ESENSIEDISLPECTAMPRSIVRAHTVNS 211
E S+ +L P S+ + V +
Sbjct: 189 EDHGSLYLDNLESLGGEPSSVQKETQVTA 217
>gi|22748765 claudin domain containing 2 [Homo sapiens]
Length = 167
Score = 36.6 bits (83), Expect = 0.018
Identities = 42/159 (26%), Positives = 70/159 (44%), Gaps = 19/159 (11%)
Query: 7 RSIQGMNILFSSWAVVLMVMGITLDKWVELISEDERAKMNHSP-WMMC----CPALWPED 61
RS+Q IL S A VLMV+ + W R + HS W C C ++ +
Sbjct: 5 RSLQSGGILLSLVANVLMVLSTATNYWT-------RQQEGHSGLWQECNHGICSSIPCQT 57
Query: 62 DLKVVRIMMTSSLGLSFLLNLILGMKFTYLIPQNKYIQLFTTILSFFSGISLLWALILYH 121
L V M ++G+ ++ +++G++ ++ Q T+ F G+ LL ALI Y
Sbjct: 58 TLAVTVACMVLAVGVG-VVGMVMGLRIRCDEGESLRGQT-TSAFLFLGGLLLLTALIGYT 115
Query: 122 NKLKQGQSMHFSNYRITWIMYTAYLNVFFLSVCGVLSLL 160
K ++ FS W ++ +L + F + G LL
Sbjct: 116 VKNAWKNNVFFS-----WSYFSGWLALPFSILAGFCFLL 149
>gi|21361975 voltage-dependent calcium channel gamma-7 subunit [Homo
sapiens]
Length = 275
Score = 33.1 bits (74), Expect = 0.20
Identities = 36/197 (18%), Positives = 82/197 (41%), Gaps = 38/197 (19%)
Query: 1 MVHVSNRSIQGMNILFSSWAVVLMVMGITLDKWVEL---------ISEDERAKMNHSPWM 51
M H S+R++ ++ +F + ++L+ + ++ D W+ + + + + ++ W
Sbjct: 1 MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWR 60
Query: 52 MC---------CPA----LWPEDDL------KVVRIMMTSS----LGLSFLLNLILGMKF 88
+C C A L PE +L +++ + T++ + L + +
Sbjct: 61 VCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNI 120
Query: 89 TYLIPQNKYIQLFTTILSFFSGISLLWALILYHNKL------KQGQSMHFSNYRITWIMY 142
++ PQ + + I SG+SL+ L+LY + + + S + +YR W
Sbjct: 121 GHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFA 180
Query: 143 TAYLNVFFLSVCGVLSL 159
A + GV+S+
Sbjct: 181 FAASSFLLKEGAGVMSV 197
>gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo
sapiens]
Length = 2506
Score = 30.4 bits (67), Expect = 1.3
Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 18/82 (21%)
Query: 5 SNRSIQGMNILFSSWAVVLMVMGITLDKWVELISEDERAKMNHSPWMMCCPALWPEDDLK 64
+N Q NILF AV+ + IT++ W +L+ A N W+ P +
Sbjct: 295 NNGITQFDNILF---AVLTVFQCITMEGWTDLLYNSNDASGNTWNWLYFIPLI------- 344
Query: 65 VVRIMMTSSLGLSFLLNLILGM 86
+G F+LNL+LG+
Sbjct: 345 --------IIGSFFMLNLVLGV 358
>gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo
sapiens]
Length = 2261
Score = 30.4 bits (67), Expect = 1.3
Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 18/82 (21%)
Query: 5 SNRSIQGMNILFSSWAVVLMVMGITLDKWVELISEDERAKMNHSPWMMCCPALWPEDDLK 64
+N Q NILF AV+ + IT++ W +L+ A N W+ P +
Sbjct: 295 NNGITQFDNILF---AVLTVFQCITMEGWTDLLYNSNDASGNTWNWLYFIPLI------- 344
Query: 65 VVRIMMTSSLGLSFLLNLILGM 86
+G F+LNL+LG+
Sbjct: 345 --------IIGSFFMLNLVLGV 358
>gi|93102367 ral guanine nucleotide dissociation stimulator-like 1
[Homo sapiens]
Length = 803
Score = 30.0 bits (66), Expect = 1.7
Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Query: 163 KLSTSSCTCLNIHKSDNECKESENSIEDISL-PECTAMPRSIVRAHTVNSLNKKV 216
KLS SS +C +IH D + I +S P C P+ R+ +V S+ V
Sbjct: 618 KLSESSSSCSSIHSMDTNSSGMSSLINPLSSPPSCNNNPKIHKRSVSVTSITSTV 672
>gi|122937323 transmembrane protein 202 [Homo sapiens]
Length = 273
Score = 29.3 bits (64), Expect = 2.8
Identities = 34/179 (18%), Positives = 69/179 (38%), Gaps = 12/179 (6%)
Query: 3 HVSNRSIQGMNILFSSWAVVLMVMGITLDKWVELISEDERAKMNHSPWMMCCPAL-WPED 61
H+ R++ G FS +LM++ ++ WV+ + ++ W +C L W
Sbjct: 53 HIYIRTLCGSLCSFS----LLMLIAMSPLNWVQFLVIKNGLELYAGLWTLCNHELCWSHT 108
Query: 62 DLKVVRIMMTSSLGLSFLLNLILGMKFTYLI------PQNKYIQLFTTILSFFSGISLLW 115
+ + + L + ++ G+ + + + L ++LSF S LL
Sbjct: 109 PKPPYYLQYSRAFFLISVFTILTGLGWLFSSWILNRGSMTTNLDLKVSMLSFISATCLLL 168
Query: 116 ALILYHNKLKQGQSMHFSNYRITWIMYTAYLNVFFLSVCGVLSLLECKLSTSSCTCLNI 174
L L+ ++ + + W Y + + F G++SLL S S N+
Sbjct: 169 CLNLFVAQV-HWHTRDAMESDLLWTYYLNWCSDIFYMFAGIISLLNYLTSRSPACDENV 226
>gi|22027551 voltage-dependent calcium channel gamma-5 subunit
isoform a [Homo sapiens]
Length = 275
Score = 28.5 bits (62), Expect = 4.8
Identities = 22/92 (23%), Positives = 40/92 (43%), Gaps = 15/92 (16%)
Query: 76 LSFLLNLILGMKFTYLIPQNKYIQLFTTILSFFSGISLLWALILY--------HNKLKQG 127
+ F+LN I ++ P + + I SG+SL+ L+LY N+ K
Sbjct: 113 IGFILNNI-----GHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDA 167
Query: 128 QSMHFSNYRITWIMYTAYLNVFFLSVCGVLSL 159
++ + NY+ W A ++ GV+S+
Sbjct: 168 ET--YFNYKYGWSFAFAAISFLLTESAGVMSV 197
>gi|31083315 G protein-coupled receptor 45 [Homo sapiens]
Length = 372
Score = 28.1 bits (61), Expect = 6.3
Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 7/49 (14%)
Query: 101 FTTILSFFSGISLLW-------ALILYHNKLKQGQSMHFSNYRITWIMY 142
FTTIL F G SL W L ++ + G S + ++ + W+ Y
Sbjct: 266 FTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGSSFYATSTCVLWLSY 314
>gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B
subunit [Homo sapiens]
Length = 2339
Score = 28.1 bits (61), Expect = 6.3
Identities = 19/74 (25%), Positives = 33/74 (44%), Gaps = 18/74 (24%)
Query: 13 NILFSSWAVVLMVMGITLDKWVELISEDERAKMNHSPWMMCCPALWPEDDLKVVRIMMTS 72
NILF A++ + IT++ W +++ A N W+ P +
Sbjct: 299 NILF---AILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLI--------------- 340
Query: 73 SLGLSFLLNLILGM 86
+G F+LNL+LG+
Sbjct: 341 IIGSFFMLNLVLGV 354
>gi|122937309 leucine rich repeat containing 4B [Homo sapiens]
Length = 713
Score = 28.1 bits (61), Expect = 6.3
Identities = 9/18 (50%), Positives = 11/18 (61%)
Query: 41 ERAKMNHSPWMMCCPALW 58
ER +NH+PW C LW
Sbjct: 304 ERVHLNHNPWHCNCDVLW 321
>gi|24497499 solute carrier family 22 member 8 [Homo sapiens]
Length = 542
Score = 27.7 bits (60), Expect = 8.3
Identities = 14/50 (28%), Positives = 26/50 (52%)
Query: 66 VRIMMTSSLGLSFLLNLILGMKFTYLIPQNKYIQLFTTILSFFSGISLLW 115
+R +M+++LG + + Y IPQ +++QL +I F +S W
Sbjct: 206 MRAIMSTALGYCYTFGQFILPGLAYAIPQWRWLQLTVSIPFFVFFLSSWW 255
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.134 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,938,047
Number of Sequences: 37866
Number of extensions: 302648
Number of successful extensions: 1028
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1021
Number of HSP's gapped (non-prelim): 17
length of query: 225
length of database: 18,247,518
effective HSP length: 99
effective length of query: 126
effective length of database: 14,498,784
effective search space: 1826846784
effective search space used: 1826846784
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.