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Search of human proteins with 13540547
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13540547 solute carrier family 2 member 10 [Homo sapiens]
(541 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13540547 solute carrier family 2 member 10 [Homo sapiens] 1069 0.0
gi|21553331 solute carrier family 2 (facilitated glucose transpo... 348 5e-96
gi|203098995 solute carrier family 2 (facilitated glucose transp... 196 3e-50
gi|223029432 solute carrier family 2 (facilitated glucose transp... 151 2e-36
gi|21361449 solute carrier family 2 (facilitated glucose transpo... 121 2e-27
gi|4507011 glucose transporter 4 [Homo sapiens] 108 1e-23
gi|134053883 intestinal facilitative glucose transporter 7 [Homo... 106 5e-23
gi|4557851 solute carrier family 2 (facilitated glucose transpor... 103 5e-22
gi|5902090 solute carrier family 2 (facilitated glucose transpor... 101 2e-21
gi|166795299 solute carrier family 2 (facilitated glucose transp... 99 1e-20
gi|4507013 solute carrier family 2 (facilitated glucose/fructose... 98 2e-20
gi|23592238 glucose transporter 14 [Homo sapiens] 96 6e-20
gi|223029430 solute carrier family 2 (facilitated glucose transp... 90 6e-18
gi|190684655 glucose transporter protein 10 isoform a [Homo sapi... 84 3e-16
gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens] 84 3e-16
gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens] 84 3e-16
gi|47933389 solute carrier family 2, member 9 protein isoform 2 ... 68 2e-11
gi|47933387 solute carrier family 2, member 9 protein isoform 1 ... 68 2e-11
gi|23510410 solute carrier family 22 member 1 isoform b [Homo sa... 57 3e-08
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap... 57 3e-08
gi|4507001 solute carrier family 22 member 2 [Homo sapiens] 57 4e-08
gi|207447703 solute carrier family 2 (facilitated glucose/fructo... 56 1e-07
gi|24497480 solute carrier family 22 member 6 isoform d [Homo sa... 54 4e-07
gi|213021148 SVOP-like isoform 1 [Homo sapiens] 51 3e-06
gi|24497478 solute carrier family 22 member 6 isoform c [Homo sa... 48 3e-05
gi|24497476 solute carrier family 22 member 6 isoform b [Homo sa... 47 3e-05
gi|20070188 solute carrier family 22 member 6 isoform a [Homo sa... 47 3e-05
gi|24308167 SV2 related protein [Homo sapiens] 47 4e-05
gi|24497499 solute carrier family 22 member 8 [Homo sapiens] 46 1e-04
gi|24497485 urate anion exchanger 1 isoform a [Homo sapiens] 42 0.001
>gi|13540547 solute carrier family 2 member 10 [Homo sapiens]
Length = 541
Score = 1069 bits (2765), Expect = 0.0
Identities = 541/541 (100%), Positives = 541/541 (100%)
Query: 1 MGHSPPVLPLCASVSLLGGLTFGYELAVISGALLPLQLDFGLSCLEQEFLVGSLLLGALL 60
MGHSPPVLPLCASVSLLGGLTFGYELAVISGALLPLQLDFGLSCLEQEFLVGSLLLGALL
Sbjct: 1 MGHSPPVLPLCASVSLLGGLTFGYELAVISGALLPLQLDFGLSCLEQEFLVGSLLLGALL 60
Query: 61 ASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACC 120
ASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACC
Sbjct: 61 ASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACC 120
Query: 121 IYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYALAGTPWGWRHMFGWATAPAVLQSL 180
IYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYALAGTPWGWRHMFGWATAPAVLQSL
Sbjct: 121 IYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYALAGTPWGWRHMFGWATAPAVLQSL 180
Query: 181 SLLFLPAGTDETATHKDLIPLQGGEAPKLGPGRPRYSFLDLFRARDNMRGRTTVGLGLVL 240
SLLFLPAGTDETATHKDLIPLQGGEAPKLGPGRPRYSFLDLFRARDNMRGRTTVGLGLVL
Sbjct: 181 SLLFLPAGTDETATHKDLIPLQGGEAPKLGPGRPRYSFLDLFRARDNMRGRTTVGLGLVL 240
Query: 241 FQQLTGQPNVLCYASTIFSSVGFHGGSSAVLASVGLGAVKVAATLTAMGLVDRAGRRALL 300
FQQLTGQPNVLCYASTIFSSVGFHGGSSAVLASVGLGAVKVAATLTAMGLVDRAGRRALL
Sbjct: 241 FQQLTGQPNVLCYASTIFSSVGFHGGSSAVLASVGLGAVKVAATLTAMGLVDRAGRRALL 300
Query: 301 LAGCALMALSVSGIGLVSFAVPMDSGPSCLAVPNATGQTGLPGDSGLLQDSSLPPIPRTN 360
LAGCALMALSVSGIGLVSFAVPMDSGPSCLAVPNATGQTGLPGDSGLLQDSSLPPIPRTN
Sbjct: 301 LAGCALMALSVSGIGLVSFAVPMDSGPSCLAVPNATGQTGLPGDSGLLQDSSLPPIPRTN 360
Query: 361 EDQREPILSTAKKTKPHPRSGDPSAPPRLALSSALPGPPLPARGHALLRWTALLCLMVFV 420
EDQREPILSTAKKTKPHPRSGDPSAPPRLALSSALPGPPLPARGHALLRWTALLCLMVFV
Sbjct: 361 EDQREPILSTAKKTKPHPRSGDPSAPPRLALSSALPGPPLPARGHALLRWTALLCLMVFV 420
Query: 421 SAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGLSWTFL 480
SAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGLSWTFL
Sbjct: 421 SAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGLSWTFL 480
Query: 481 LYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQKRRFTLSFGHRQNSTGIPYSRIEISAA 540
LYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQKRRFTLSFGHRQNSTGIPYSRIEISAA
Sbjct: 481 LYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQKRRFTLSFGHRQNSTGIPYSRIEISAA 540
Query: 541 S 541
S
Sbjct: 541 S 541
>gi|21553331 solute carrier family 2 (facilitated glucose
transporter), member 12 [Homo sapiens]
Length = 617
Score = 348 bits (894), Expect = 5e-96
Identities = 214/547 (39%), Positives = 297/547 (54%), Gaps = 64/547 (11%)
Query: 10 LCASVSLLGGLTFGYELAVISGALLPLQLDFGLSCLEQEFLVGSLLLGALLASLVGGFLI 69
L + + + GL GYEL +ISGALL ++ LSC EQE +V SL++GALLASL GG LI
Sbjct: 42 LSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCHEQEMVVSSLVIGALLASLTGGVLI 101
Query: 70 DCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACCIYVSELVGP 129
D YGR+ AI+ S+ +L GSL L L+ S L++GR +G +ISLSS+A C+Y++E+
Sbjct: 102 DRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQ 161
Query: 130 RQRGVLVSLYEAGITVGILLSYALNYALAGTPWGWRHMFGWATAPAVLQSLSLLFLPAGT 189
+RG+LVSL E I +GIL +Y NYA A GW++MFG VLQ++++ FLP
Sbjct: 162 HRRGLLVSLNELMIVIGILSAYISNYAFANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSP 221
Query: 190 DETATHKDLIPLQGGEAPKLGPGRP-------------------RYSFLDLFRARDNMRG 230
+G + LG R +YSF DLFR++DNMR
Sbjct: 222 RFLVMKGQ----EGAASKVLGRLRALSDTTEELTVIKSSLKDEYQYSFWDLFRSKDNMRT 277
Query: 231 RTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGSSAVLASVGLGAVKVAATLTAMGL 290
R +GL LV F Q+TGQPN+L YAST+ SVGF +A LAS G+G VKV +T+ A L
Sbjct: 278 RIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLL 337
Query: 291 VDRAGRRALLLAGCALMALSVSGIGLVSFAVPMDS--------------------GPSCL 330
VD G + L G ++MA S+ +G+V+ + M+ GP L
Sbjct: 338 VDHVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFTHICRSHNSINQSLDESVIYGPGNL 397
Query: 331 AVPNATGQTGLPGDSGLLQDSSLP---PIPRTNEDQREPILSTAKKTKPHPRSGDPSAPP 387
+ N T + G S + S +P + + E +L+ + DP P
Sbjct: 398 STNNNTLRDHFKGISSHSRSSLMPLRNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDVP 457
Query: 388 RLALSSALPGPPLPARGHALLRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRA 447
A L+W +L L+V+V+AFS G GP+ WLVLSEI+P IRGRA
Sbjct: 458 ------------------AFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRA 499
Query: 448 FAFCNSFNWAANLFISLSFLDLIGTIGLSWTFLLYGLTAVLGLGFIYLFVPETKGQSLAE 507
A +S NW NL ISL+FL + IGL W +Y + ++ L F+ +F+PETKG SL +
Sbjct: 500 MALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQ 559
Query: 508 IDQQFQK 514
I + K
Sbjct: 560 ISMELAK 566
>gi|203098995 solute carrier family 2 (facilitated glucose
transporter), member 13 [Homo sapiens]
Length = 648
Score = 196 bits (499), Expect = 3e-50
Identities = 165/573 (28%), Positives = 246/573 (42%), Gaps = 56/573 (9%)
Query: 4 SPPVLPLCASVSLLGGLTFGYELAVISGALLPLQLDFGLSCLEQEFLVGSLLLGALLASL 63
+P + + A S LGG FGY+ V+SGA+L L+ L L QE LV S + A +++L
Sbjct: 77 TPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQELLVSSTVGAAAVSAL 136
Query: 64 VGGFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACCIYV 123
GG L +GR+ AIL ++ + AGS L A + L+ GR VVG I ++SM +Y+
Sbjct: 137 AGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYI 196
Query: 124 SELVGPRQRGVLVSLYEAGITVGILLSYALNYALAGTPW-GWRHMFGWATAPAVLQSLSL 182
+E+ P RG LV++ IT G + ++ A + GWR+M G A PAV+Q
Sbjct: 197 AEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGF 256
Query: 183 LFLPAG--------------------------TDETATHKDLIPLQGGEAPKLGPGRPRY 216
LFLP +E + K+ I + E GP
Sbjct: 257 LFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSAGP----- 311
Query: 217 SFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGSSAVLASVGL 276
+ + R VG GL +FQQL+G ++ Y++TI G A+ +
Sbjct: 312 -VICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVT 370
Query: 277 GAVKVAATLTAMGLVDRAGRRALLLAGCA--LMALSVSGIGLVSFA-----------VPM 323
TL + LV++ GRR L A +AL + +G V A P
Sbjct: 371 AFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSPRITFKPIAPS 430
Query: 324 DSGPSCLAVPNATGQTGLPGDSGLLQDSSLPPIPRTNEDQREPILSTAKKTKPHPRSGDP 383
+C + + L D G + + + P+ + R +
Sbjct: 431 GQNATCTRY-SYCNECMLDPDCGFCYKMNKSTV---IDSSCVPVNKASTNEAAWGRCENE 486
Query: 384 SAPPRLALSSALPGPPLPARGHALLRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEI 443
+ + A P P WTALL L++++ F+ G GP+ W V SEIYP+
Sbjct: 487 TKFKTEDIFWAYNFCPTP------YSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWA 540
Query: 444 RGRAFAFCNSFNWAANLFISLSFLDLIGTIGLSWTFLLYGLTAVLGLGFIYLFVPETKGQ 503
R A + NW N+ +SL+FL + F LY A +GL FIY +PETKG+
Sbjct: 541 RSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGK 600
Query: 504 SLAEIDQQFQKRRFTLSFGHRQNSTGIPYSRIE 536
L EI+ F R T I Y R++
Sbjct: 601 KLEEIESLFDNRLCTCGTSDSDEGRYIEYIRVK 633
>gi|223029432 solute carrier family 2 (facilitated glucose
transporter), member 6 isoform 1 [Homo sapiens]
Length = 507
Score = 151 bits (381), Expect = 2e-36
Identities = 150/536 (27%), Positives = 223/536 (41%), Gaps = 102/536 (19%)
Query: 10 LCASVSLLGGLTFGYELAVISGALLPLQL----DFGLSCLEQEFLVGSLLLGALLASLVG 65
L ++LG +FGY L S + L+ D L+ + + LGA L
Sbjct: 40 LATFAAVLGNFSFGYALVYTSPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSA 99
Query: 66 GFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACCIYVSE 125
L D GRK +I+ S + AG + A L L+LGR + GFA L++ +YVSE
Sbjct: 100 MILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSE 159
Query: 126 LVGPRQRGVLVSLYEAGITVGILLSYALNYALAGTPWGWRHMFGWATAPAVLQSLSLLFL 185
+ P RG L + + G L YAL L PW W + G AP ++ L L F+
Sbjct: 160 IAPPGVRGALGATPQLMAVFGSLSLYALGLLL---PWRWLAVAG--EAPVLIMILLLSFM 214
Query: 186 P--------AGTDETATHKDLIPLQGGEAPKLGPGRPRYSFLDLFRARDNMRGRT----- 232
P G DE A + L L+G + + + +DN+R ++
Sbjct: 215 PNSPRFLLSRGRDEEAL-RALAWLRGTDVDV---------HWEFEQIQDNVRRQSSRVSW 264
Query: 233 ------------TVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGSSAVLASVGLGAVK 280
TV L + L QQLTG +L Y +IF S A VG AV+
Sbjct: 265 AEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAIVG--AVR 322
Query: 281 VAATLTAMGLVDRAGRRALLLAGCALMALSVSGIGLVSFAVPMDSGPSCLAVPNATGQTG 340
+ + L A +D AGR+ LL A+M + +GL + GP L+ PN+T G
Sbjct: 323 LLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLY-----IHFGPRPLS-PNSTA--G 374
Query: 341 LPGDSGLLQDSSLPPIPRTNEDQREPILSTAKKTKPHPRSGDPSAPPRLALSSALPGPPL 400
L +S D +P+ + A
Sbjct: 375 LESESW--------------GDLAQPLAAPA----------------------------- 391
Query: 401 PARGHALLRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANL 460
L LL M+F+ ++ G+GP+TWL++SE+ P+ RG A C +W
Sbjct: 392 -----GYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAF 446
Query: 461 FISLSFLDLIGTIGLSWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQKRR 516
++ SFL ++ T GL F + ++ L F VPETKG+SL +I+ F+ R
Sbjct: 447 VLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFFRTGR 502
>gi|21361449 solute carrier family 2 (facilitated glucose
transporter), member 8 [Homo sapiens]
Length = 477
Score = 121 bits (303), Expect = 2e-27
Identities = 101/321 (31%), Positives = 150/321 (46%), Gaps = 26/321 (8%)
Query: 10 LCASVSLLGGLTFGYELAVISGALLPLQLDFG----LSCLEQEFLVGSLLLGALLASLVG 65
L A + LG L+FG+ L S A+ LQ L + + LGA ++G
Sbjct: 28 LAAFAAALGPLSFGFALGYSSPAIPSLQRAAPPAPRLDDAAASWFGAVVTLGAAAGGVLG 87
Query: 66 GFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACCIYVSE 125
G+L+D GRK ++L ++ +AG + A + L+ GR + G A ++S+ +Y+SE
Sbjct: 88 GWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLACGVASLVAPVYISE 147
Query: 126 LVGPRQRGVLVSLYEAGITVGILLSYALNYALAGTPWGWRHMFGWATAPAVLQSLSLLFL 185
+ P RG+L S + + VGILL+Y LAG WR + P L L + F+
Sbjct: 148 IAYPAVRGLLGSCVQLMVVVGILLAY-----LAGWVLEWRWLAVLGCVPPSLMLLLMCFM 202
Query: 186 PAGTDETAT-HKDLIPL----------QGGEAPKLGPGRPRYSFLDLFRARDNMRGRTTV 234
P T H+ + QG E P +G SF + + +
Sbjct: 203 PETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIG---AEQSFHLALLRQPGIYKPFII 259
Query: 235 GLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGSSAVLASVGLGAVKVAATLTAMGLVDRA 294
G+ L+ FQQL+G V+ YA TIF F S LASV +G ++V T A ++DRA
Sbjct: 260 GVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSS---LASVVVGVIQVLFTAVAALIMDRA 316
Query: 295 GRRALLLAGCALMALSVSGIG 315
GRR LL+ +M S S G
Sbjct: 317 GRRLLLVLSGVVMVFSTSAFG 337
Score = 77.8 bits (190), Expect = 2e-14
Identities = 40/135 (29%), Positives = 69/135 (51%), Gaps = 2/135 (1%)
Query: 381 GDPSAPPRLALSSALPGPPLPARGHALLRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYP 440
G P +A+S+ + P+ A L W A+ + +F++ F+ G+GP+ WL++SEI+P
Sbjct: 345 GGPGNSSHVAISAPVSAQPVDAS--VGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFP 402
Query: 441 VEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGLSWTFLLYGLTAVLGLGFIYLFVPET 500
+ ++G A C NW ++ F L+ + F L + + F VPET
Sbjct: 403 LHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPET 462
Query: 501 KGQSLAEIDQQFQKR 515
KG++L +I F+ R
Sbjct: 463 KGKTLEQITAHFEGR 477
>gi|4507011 glucose transporter 4 [Homo sapiens]
Length = 509
Score = 108 bits (271), Expect = 1e-23
Identities = 101/342 (29%), Positives = 154/342 (45%), Gaps = 47/342 (13%)
Query: 8 LPLCASVSLLGGLTFGYELAVISGALLPLQLDFGLSCLEQE------------------F 49
L L ++LG L FGY + VI+ ++ + + L ++
Sbjct: 24 LVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWAL 83
Query: 50 LVGSLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLA---WLVLGRA 106
V +G +++S + G + GRK+A+L +N++ + G +GLA + A L+LGR
Sbjct: 84 SVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRF 143
Query: 107 VVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNY-ALAGTPWGWR 165
++G L+S +YV E+ RG L +L + I +GIL++ L +L GT W
Sbjct: 144 LIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWP 203
Query: 166 HMFGWATAPAVLQSLSLLFLPAGTD--------ETATHKDLIPLQG------------GE 205
+ G PA+LQ + L F P E K L L G E
Sbjct: 204 LLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVSGVLAELKDE 263
Query: 206 APKLGPGRPRYSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHG 265
KL RP S L L +R + R + + L L QQL+G V Y+++IF + G
Sbjct: 264 KRKLERERP-LSLLQLLGSRTH-RQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGV-- 319
Query: 266 GSSAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALM 307
A++G G V TL ++ LV+RAGRR L L G A M
Sbjct: 320 -GQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGM 360
Score = 60.1 bits (144), Expect = 5e-09
Identities = 34/110 (30%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 408 LRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFL 467
+ + +++ + FV+ F G GP+ W +++E++ R A A NW +N I + F
Sbjct: 380 MSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQ 439
Query: 468 DLIGTIGLSWTFLLYGLTAVLGLGFI---YLFVPETKGQSLAEIDQQFQK 514
+ +G + FLL+ AVL LGF +L VPET+G++ +I F +
Sbjct: 440 YVAEAMG-PYVFLLF---AVLLLGFFIFTFLRVPETRGRTFDQISAAFHR 485
>gi|134053883 intestinal facilitative glucose transporter 7 [Homo
sapiens]
Length = 512
Score = 106 bits (265), Expect = 5e-23
Identities = 101/359 (28%), Positives = 162/359 (45%), Gaps = 44/359 (12%)
Query: 5 PPVLPLCASVSLLGGLTFGYELAVISGALLPLQLDFGLSCLEQE--FLVGSLLL------ 56
P +L S + +GY L+V++ + + + E+ F+ G L+L
Sbjct: 21 PTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLMLLLWSCT 80
Query: 57 ------GALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGL---AGSLAWLVLGRAV 107
G LL SL+ G L+D GRK +L +N+ + ++ +G+ A + +V R V
Sbjct: 81 VSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVV 140
Query: 108 VGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNY-ALAGTPWGWRH 166
+G +S A +Y+ EL RG++ ++ E + VG+ L+ + A+ G P GW
Sbjct: 141 LGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPV 200
Query: 167 MFGWATAPAVLQSLSLLFLPAGT--------DETATHKDLIPLQG------------GEA 206
+ PA+LQ L+L F P DE + L L+G EA
Sbjct: 201 LLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMRAEA 260
Query: 207 PKLGPGRPRYSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGG 266
+ S L L R ++R + + L+ QQL+G + YA TI++S G
Sbjct: 261 -RAERAEGHLSVLHLCALR-SLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAGVEAA 318
Query: 267 SSAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAG---CALMALSVSGIGLVSFAVP 322
S + +VG G V + T+T+ LV+R GRR LLLAG C L ++ + L VP
Sbjct: 319 HSQYV-TVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNRVP 376
Score = 62.4 bits (150), Expect = 1e-09
Identities = 32/108 (29%), Positives = 59/108 (54%), Gaps = 1/108 (0%)
Query: 408 LRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFL 467
L + ++C+ +++ S G PV +V +EI+ R AF + +W N I F
Sbjct: 378 LSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFP 437
Query: 468 DLIGTIGLSWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQKR 515
+ IG +++F+++ +L +IY+ +PETKG++ EI++ F KR
Sbjct: 438 SIQEAIG-AYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKR 484
>gi|4557851 solute carrier family 2 (facilitated glucose
transporter), member 2 [Homo sapiens]
Length = 524
Score = 103 bits (256), Expect = 5e-22
Identities = 85/292 (29%), Positives = 138/292 (47%), Gaps = 29/292 (9%)
Query: 51 VGSLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLG---LAGSLAWLVLGRAV 107
V S +G + AS GG+L D GR +A+L +N++ L G+L +G L S ++ GR++
Sbjct: 101 VSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSI 160
Query: 108 VGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYA-LAGTPWGWRH 166
G L S +Y+ E+ RG L + ++ I GIL+S + + G W
Sbjct: 161 SGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHI 220
Query: 167 MFGWATAPAVLQSLSLLFLPAGT--------DETATHKDLIPLQGGE-----------AP 207
+ G + A+LQSL L F P +E + L L+G +
Sbjct: 221 LLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKER 280
Query: 208 KLGPGRPRYSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGS 267
+ + S + LF + R V L L + QQ +G + Y+++IF + G S
Sbjct: 281 EEASSEQKVSIIQLF-TNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGI---S 336
Query: 268 SAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMALSV--SGIGLV 317
V A++G+GAV + T ++ LV++AGRR+L L G + M + +GLV
Sbjct: 337 KPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLV 388
Score = 65.5 bits (158), Expect = 1e-10
Identities = 35/108 (32%), Positives = 55/108 (50%), Gaps = 1/108 (0%)
Query: 408 LRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFL 467
+ + +++ + +FVS F G GP+ W +++E + R A A NW N ++L F
Sbjct: 396 MSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQ 455
Query: 468 DLIGTIGLSWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQKR 515
+ G FL G+ L F + VPETKG+S EI +FQK+
Sbjct: 456 YIADFCGPYVFFLFAGVLLAFTL-FTFFKVPETKGKSFEEIAAEFQKK 502
>gi|5902090 solute carrier family 2 (facilitated glucose
transporter), member 3 [Homo sapiens]
Length = 496
Score = 101 bits (251), Expect = 2e-21
Identities = 93/342 (27%), Positives = 156/342 (45%), Gaps = 45/342 (13%)
Query: 6 PVLPLCASVSLLGGLTFGYELAVISGALLPLQLDFGLSCLEQ------EFLVGSLL---- 55
P L +V+ +G FGY VI+ ++ + ++ E L+ SL
Sbjct: 8 PALIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSV 67
Query: 56 ----LGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGL---AGSLAWLVLGRAVV 108
+G ++ S G ++ +GR+ ++L NL+ + G +GL A S+ L+LGR V+
Sbjct: 68 AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVI 127
Query: 109 GFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLS--YALNYALAGTPWGWRH 166
G L + +Y+ E+ RG +L + GI VGIL++ + L + L G+ W
Sbjct: 128 GLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFIL-GSEELWPL 186
Query: 167 MFGWATAPAVLQSLSLLFLPAGT-------DETATHKDLIPLQGG-------------EA 206
+ G+ PA+LQS +L F P E K ++ G E+
Sbjct: 187 LLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDES 246
Query: 207 PKLGPGRPRYSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGG 266
++ + + + L+LFR + R + + L L QQL+G V Y++ IF G
Sbjct: 247 ARMSQEK-QVTVLELFRV-SSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQ-- 302
Query: 267 SSAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMA 308
+ A++G G V T+ ++ LV+RAGRR L + G MA
Sbjct: 303 -EPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMA 343
Score = 60.1 bits (144), Expect = 5e-09
Identities = 28/98 (28%), Positives = 53/98 (54%), Gaps = 1/98 (1%)
Query: 416 LMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGL 475
++VFV+ F G GP+ W +++E++ R A A NW +N + L F +G
Sbjct: 370 ILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLG- 428
Query: 476 SWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQ 513
++ F+++ + L F + VPET+G++ +I + F+
Sbjct: 429 AYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFE 466
>gi|166795299 solute carrier family 2 (facilitated glucose
transporter), member 1 [Homo sapiens]
Length = 492
Score = 98.6 bits (244), Expect = 1e-20
Identities = 90/338 (26%), Positives = 149/338 (44%), Gaps = 41/338 (12%)
Query: 8 LPLCASVSLLGGLTFGYELAVISGALLPLQLDFGLSCLEQ--------------EFLVGS 53
L L ++LG L FGY VI+ ++ + + + + V
Sbjct: 12 LMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAI 71
Query: 54 LLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLG---LAGSLAWLVLGRAVVGF 110
+G ++ S G ++ +GR+ ++L NL+ ++ +G L S L+LGR ++G
Sbjct: 72 FSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGV 131
Query: 111 AISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNY-ALAGTPWGWRHMFG 169
L++ +YV E+ RG L +L++ GI VGIL++ ++ G W +
Sbjct: 132 YCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLS 191
Query: 170 WATAPAVLQSLSLLFLPAG--------TDETATHKDLIPLQGG-----------EAPKLG 210
PA+LQ + L F P +E L L+G E +
Sbjct: 192 IIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMKEESRQM 251
Query: 211 PGRPRYSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGSSAV 270
+ + L+LFR+ R + + L L QQL+G V Y+++IF G V
Sbjct: 252 MREKKVTILELFRS-PAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGV---QQPV 307
Query: 271 LASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMA 308
A++G G V A T+ ++ +V+RAGRR L L G A MA
Sbjct: 308 YATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMA 345
Score = 59.3 bits (142), Expect = 9e-09
Identities = 30/107 (28%), Positives = 56/107 (52%), Gaps = 1/107 (0%)
Query: 408 LRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFL 467
+ + +++ + FV+ F G GP+ W +++E++ R A A NW +N + + F
Sbjct: 364 MSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQ 423
Query: 468 DLIGTIGLSWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQK 514
+ G + F+++ + VL F Y VPETKG++ EI F++
Sbjct: 424 YVEQLCG-PYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQ 469
>gi|4507013 solute carrier family 2 (facilitated glucose/fructose
transporter), member 5 isoform 1 [Homo sapiens]
Length = 501
Score = 97.8 bits (242), Expect = 2e-20
Identities = 99/344 (28%), Positives = 152/344 (44%), Gaps = 44/344 (12%)
Query: 7 VLPLCASVSLLGG-LTFGYELAVISGALLPLQL---------------DFGLSCLEQEFL 50
VL L ++ G +GY +A ++ L +Q DF L+ L
Sbjct: 16 VLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLL-WSVT 74
Query: 51 VGSLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLG---LAGSLAWLVLGRAV 107
V G + SL+ G L++ +GRK A+L +N+ + ++ +G +A S +++ R +
Sbjct: 75 VSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLL 134
Query: 108 VGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLS--YALNYALAGTPWGWR 165
VG +SS +Y+ EL RG L + + ITVGIL++ + L LA GW
Sbjct: 135 VGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVD-GWP 193
Query: 166 HMFGWATAPAVLQSLSLLFLPAG--------TDETATHKDLIPLQGGEAPKLGPGRPR-- 215
+ G PA LQ L L F P DE A K L L+G ++ R
Sbjct: 194 ILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIRQE 253
Query: 216 ---------YSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGG 266
S L LFR R ++R + + L+ QQL+G + YA I+ S G
Sbjct: 254 DEAEKAAGFISVLKLFRMR-SLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGV-PE 311
Query: 267 SSAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMALS 310
+ G GAV V T A+ +V+ GRR LLL G ++ ++
Sbjct: 312 EHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIA 355
Score = 57.4 bits (137), Expect = 3e-08
Identities = 30/105 (28%), Positives = 60/105 (57%), Gaps = 1/105 (0%)
Query: 410 WTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDL 469
+ +++C++ +V + G P+ L+++EI+ R AF S +W +N + L F +
Sbjct: 374 YISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFI 433
Query: 470 IGTIGLSWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQK 514
+G ++F+++ + +L +I+L VPETK ++ EI+Q F K
Sbjct: 434 QEGLG-PYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTK 477
>gi|23592238 glucose transporter 14 [Homo sapiens]
Length = 520
Score = 96.3 bits (238), Expect = 6e-20
Identities = 92/341 (26%), Positives = 152/341 (44%), Gaps = 43/341 (12%)
Query: 6 PVLPLCASVSLLGGLTFGYELAVISGA------LLPLQLDFGLSCLEQEFLVGSLL---- 55
P L +V+ +G FGY VI+ + L + E L+ +L
Sbjct: 32 PALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSV 91
Query: 56 ----LGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGL---AGSLAWLVLGRAVV 108
+G ++ S G ++ +GR+ ++L NL+ G +GL A S+ L+LGR V+
Sbjct: 92 AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVI 151
Query: 109 GFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYAL-AGTPWGWRHM 167
G L + +Y+ E+ RG +L + GI +GIL++ L G+ W +
Sbjct: 152 GLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVL 211
Query: 168 FGWATAPAVLQSLSL---------LFLPAGTDETATH--------KDL---IPLQGGEAP 207
G+ PA+LQS +L L + +E AT +D+ I E+
Sbjct: 212 LGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDESA 271
Query: 208 KLGPGRPRYSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGS 267
++ + + + L+LFR + R + + L L QQL+G V Y++ IF G
Sbjct: 272 RMSQEK-QVTVLELFRV-SSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV---Q 326
Query: 268 SAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMA 308
+ A++ G V TL ++ LV+RAGRR L + G MA
Sbjct: 327 QPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMA 367
Score = 60.5 bits (145), Expect = 4e-09
Identities = 28/98 (28%), Positives = 53/98 (54%), Gaps = 1/98 (1%)
Query: 416 LMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGL 475
++VFV+ F G GP+ W +++E++ R A A NW +N + L F +G
Sbjct: 394 ILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLG- 452
Query: 476 SWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQ 513
++ F+++ + L F + VPET+G++ +I + F+
Sbjct: 453 AYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFE 490
>gi|223029430 solute carrier family 2 (facilitated glucose
transporter), member 6 isoform 2 [Homo sapiens]
Length = 445
Score = 89.7 bits (221), Expect = 6e-18
Identities = 96/325 (29%), Positives = 140/325 (43%), Gaps = 56/325 (17%)
Query: 10 LCASVSLLGGLTFGYELAVISGALLPLQL----DFGLSCLEQEFLVGSLLLGALLASLVG 65
L ++LG +FGY L S + L+ D L+ + + LGA L
Sbjct: 40 LATFAAVLGNFSFGYALVYTSPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSA 99
Query: 66 GFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACCIYVSE 125
L D GRK +I+ S + AG + A L L+LGR + GFA L++ +YVSE
Sbjct: 100 MILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSE 159
Query: 126 LVGPRQRGVLVSLYEAGITVGILLSYALNYALAGTPWGWRHMFGWATAPAVLQSLSLLFL 185
+ P RG L + + G L YAL L PW W + G AP ++ L L F+
Sbjct: 160 IAPPGVRGALGATPQLMAVFGSLSLYALGLLL---PWRWLAVAG--EAPVLIMILLLSFM 214
Query: 186 P--------AGTDETATHKDLIPLQGGEAPKLGPGRPRYSFLDLFRARDNMRGRT----- 232
P G DE A + L L+G + + + +DN+R ++
Sbjct: 215 PNSPRFLLSRGRDEEAL-RALAWLRGTDVD---------VHWEFEQIQDNVRRQSSRVSW 264
Query: 233 ------------TVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGSSAVLA-----SVG 275
TV L + L QQLTG +L Y +IF S+AVL +
Sbjct: 265 AEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFD-------STAVLLPPKDDAAI 317
Query: 276 LGAVKVAATLTAMGLVDRAGRRALL 300
+GAV++ + L A +D AGR+ LL
Sbjct: 318 VGAVRLLSVLIAALTMDLAGRKVLL 342
Score = 80.5 bits (197), Expect = 4e-15
Identities = 37/101 (36%), Positives = 60/101 (59%)
Query: 416 LMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGL 475
+++FVS ++ G+GP+TWL++SE+ P+ RG A C +W ++ SFL ++ T GL
Sbjct: 340 VLLFVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGL 399
Query: 476 SWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQKRR 516
F + ++ L F VPETKG+SL +I+ F+ R
Sbjct: 400 QVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFFRTGR 440
>gi|190684655 glucose transporter protein 10 isoform a [Homo
sapiens]
Length = 503
Score = 84.3 bits (207), Expect = 3e-16
Identities = 90/339 (26%), Positives = 145/339 (42%), Gaps = 42/339 (12%)
Query: 7 VLPLCASVSLLGGLTFGYELAVISGALLPLQ--------------LDFGLSCLEQEFLVG 52
+L +CA+ + G FGY L++I+ L +Q L L L +V
Sbjct: 21 LLTICAA-GIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 79
Query: 53 SLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGL---AGSLAWLVLGRAVVG 109
LG L +L+ G L GRK+++L +N+ +++ ++ G AGS ++LGR +VG
Sbjct: 80 LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 139
Query: 110 FAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYA-LAGTPWGWRHMF 168
+S +Y+ E RG + +GI++ + L G P W +
Sbjct: 140 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 199
Query: 169 GWATAPAVLQSLSLLFLPAGT--------DETATHKDLIPLQG-----GEAPKLGPGRPR 215
P LQ SL LP D A L L+G GE +L R
Sbjct: 200 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 259
Query: 216 YSFL------DLFRARDNMRGRTT-VGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGSS 268
+LF+ R R T+ V LG + +L G +V YAS++F G +
Sbjct: 260 CQGCRARRPWELFQHRALRRQVTSLVVLGSAM--ELCGNDSVYAYASSVFRKAGVPE-AK 316
Query: 269 AVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALM 307
A +G G+ ++ + + +++R GRR LL+ G +LM
Sbjct: 317 IQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLM 355
Score = 51.6 bits (122), Expect = 2e-06
Identities = 32/113 (28%), Positives = 53/113 (46%), Gaps = 8/113 (7%)
Query: 410 WT---ALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSF 466
WT A+ C+ F+ +F G VT ++ +E++ R A C + W + + L F
Sbjct: 374 WTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGF 433
Query: 467 LDLIGTIGLSWTFLLYGLTAVLGLGFIY--LFVPETKGQSLAEIDQQFQKRRF 517
++ + FL V G IY LF+PETKG++ EI ++ + F
Sbjct: 434 PFIMEALS---HFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNF 483
>gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]
Length = 496
Score = 84.3 bits (207), Expect = 3e-16
Identities = 90/339 (26%), Positives = 145/339 (42%), Gaps = 42/339 (12%)
Query: 7 VLPLCASVSLLGGLTFGYELAVISGALLPLQ--------------LDFGLSCLEQEFLVG 52
+L +CA+ + G FGY L++I+ L +Q L L L +V
Sbjct: 14 LLTICAA-GIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 72
Query: 53 SLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGL---AGSLAWLVLGRAVVG 109
LG L +L+ G L GRK+++L +N+ +++ ++ G AGS ++LGR +VG
Sbjct: 73 LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 132
Query: 110 FAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYA-LAGTPWGWRHMF 168
+S +Y+ E RG + +GI++ + L G P W +
Sbjct: 133 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 192
Query: 169 GWATAPAVLQSLSLLFLPAGT--------DETATHKDLIPLQG-----GEAPKLGPGRPR 215
P LQ SL LP D A L L+G GE +L R
Sbjct: 193 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 252
Query: 216 YSFL------DLFRARDNMRGRTT-VGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGSS 268
+LF+ R R T+ V LG + +L G +V YAS++F G +
Sbjct: 253 CQGCRARRPWELFQHRALRRQVTSLVVLGSAM--ELCGNDSVYAYASSVFRKAGVPE-AK 309
Query: 269 AVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALM 307
A +G G+ ++ + + +++R GRR LL+ G +LM
Sbjct: 310 IQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLM 348
Score = 51.6 bits (122), Expect = 2e-06
Identities = 32/113 (28%), Positives = 53/113 (46%), Gaps = 8/113 (7%)
Query: 410 WT---ALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSF 466
WT A+ C+ F+ +F G VT ++ +E++ R A C + W + + L F
Sbjct: 367 WTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGF 426
Query: 467 LDLIGTIGLSWTFLLYGLTAVLGLGFIY--LFVPETKGQSLAEIDQQFQKRRF 517
++ + FL V G IY LF+PETKG++ EI ++ + F
Sbjct: 427 PFIMEALS---HFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNF 476
>gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]
Length = 499
Score = 84.3 bits (207), Expect = 3e-16
Identities = 90/339 (26%), Positives = 145/339 (42%), Gaps = 42/339 (12%)
Query: 7 VLPLCASVSLLGGLTFGYELAVISGALLPLQ--------------LDFGLSCLEQEFLVG 52
+L +CA+ + G FGY L++I+ L +Q L L L +V
Sbjct: 17 LLTICAA-GIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 75
Query: 53 SLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGL---AGSLAWLVLGRAVVG 109
LG L +L+ G L GRK+++L +N+ +++ ++ G AGS ++LGR +VG
Sbjct: 76 LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 135
Query: 110 FAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYA-LAGTPWGWRHMF 168
+S +Y+ E RG + +GI++ + L G P W +
Sbjct: 136 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 195
Query: 169 GWATAPAVLQSLSLLFLPAGT--------DETATHKDLIPLQG-----GEAPKLGPGRPR 215
P LQ SL LP D A L L+G GE +L R
Sbjct: 196 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 255
Query: 216 YSFL------DLFRARDNMRGRTT-VGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGSS 268
+LF+ R R T+ V LG + +L G +V YAS++F G +
Sbjct: 256 CQGCRARRPWELFQHRALRRQVTSLVVLGSAM--ELCGNDSVYAYASSVFRKAGVPE-AK 312
Query: 269 AVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALM 307
A +G G+ ++ + + +++R GRR LL+ G +LM
Sbjct: 313 IQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLM 351
Score = 51.6 bits (122), Expect = 2e-06
Identities = 32/113 (28%), Positives = 53/113 (46%), Gaps = 8/113 (7%)
Query: 410 WT---ALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSF 466
WT A+ C+ F+ +F G VT ++ +E++ R A C + W + + L F
Sbjct: 370 WTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGF 429
Query: 467 LDLIGTIGLSWTFLLYGLTAVLGLGFIY--LFVPETKGQSLAEIDQQFQKRRF 517
++ + FL V G IY LF+PETKG++ EI ++ + F
Sbjct: 430 PFIMEALS---HFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNF 479
>gi|47933389 solute carrier family 2, member 9 protein isoform 2
[Homo sapiens]
Length = 511
Score = 67.8 bits (164), Expect = 2e-11
Identities = 72/284 (25%), Positives = 120/284 (42%), Gaps = 30/284 (10%)
Query: 49 FLVGSLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGL---AGSLAWLVLGR 105
F +G L+ G L+ ++G L GRK +L +N ++ +L + AG+ L++GR
Sbjct: 88 FAIGGLV-GTLIVKMIGKVL----GRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGR 142
Query: 106 AVVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYA-LAGTPWGW 164
++G ++ +Y+SE+ RG L + I +G+ L L G W
Sbjct: 143 FIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTW 202
Query: 165 RHMFGWATAPAVLQSLSLLFLPAGT--------DETATHKDLIPLQGGE------APKLG 210
++FG PAV+Q LSL FLP +E K G L
Sbjct: 203 PYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLA 262
Query: 211 PGRPR-----YSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHG 265
R + S L+L RA +R + + + QL G + Y ++IF G
Sbjct: 263 ESRVQRSIRLVSVLELLRA-PYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGI-P 320
Query: 266 GSSAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMAL 309
+ ++ G ++ A + + +++ GRR LL+ G LM L
Sbjct: 321 PAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGL 364
Score = 57.0 bits (136), Expect = 4e-08
Identities = 27/106 (25%), Positives = 57/106 (53%), Gaps = 1/106 (0%)
Query: 410 WTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDL 469
+ +++ ++ +++F G G + +++ E + R AF + NW +N + L F +
Sbjct: 384 YLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFI 443
Query: 470 IGTIGLSWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQKR 515
++ ++ FL++ + G ++Y +PETK ++ AEI Q F KR
Sbjct: 444 QKSLD-TYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKR 488
>gi|47933387 solute carrier family 2, member 9 protein isoform 1
[Homo sapiens]
Length = 540
Score = 67.8 bits (164), Expect = 2e-11
Identities = 72/284 (25%), Positives = 120/284 (42%), Gaps = 30/284 (10%)
Query: 49 FLVGSLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGL---AGSLAWLVLGR 105
F +G L+ G L+ ++G L GRK +L +N ++ +L + AG+ L++GR
Sbjct: 117 FAIGGLV-GTLIVKMIGKVL----GRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGR 171
Query: 106 AVVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYA-LAGTPWGW 164
++G ++ +Y+SE+ RG L + I +G+ L L G W
Sbjct: 172 FIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTW 231
Query: 165 RHMFGWATAPAVLQSLSLLFLPAGT--------DETATHKDLIPLQGGE------APKLG 210
++FG PAV+Q LSL FLP +E K G L
Sbjct: 232 PYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLA 291
Query: 211 PGRPR-----YSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHG 265
R + S L+L RA +R + + + QL G + Y ++IF G
Sbjct: 292 ESRVQRSIRLVSVLELLRA-PYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGI-P 349
Query: 266 GSSAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMAL 309
+ ++ G ++ A + + +++ GRR LL+ G LM L
Sbjct: 350 PAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGL 393
Score = 57.0 bits (136), Expect = 4e-08
Identities = 27/106 (25%), Positives = 57/106 (53%), Gaps = 1/106 (0%)
Query: 410 WTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDL 469
+ +++ ++ +++F G G + +++ E + R AF + NW +N + L F +
Sbjct: 413 YLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFI 472
Query: 470 IGTIGLSWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQKR 515
++ ++ FL++ + G ++Y +PETK ++ AEI Q F KR
Sbjct: 473 QKSLD-TYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKR 517
>gi|23510410 solute carrier family 22 member 1 isoform b [Homo
sapiens]
Length = 506
Score = 57.4 bits (137), Expect = 3e-08
Identities = 75/302 (24%), Positives = 116/302 (38%), Gaps = 57/302 (18%)
Query: 37 QLDFGLSCLEQEFLVGSLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGLAG 96
+LD SCL FL GSL +G + D +GRK +LG+ LV + + +
Sbjct: 147 KLDLFQSCLNAGFLFGSLGVG---------YFADRFGRKLCLLGTVLVNAVSGVLMAFSP 197
Query: 97 SLAWLVLGRAVVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYA 156
+ ++L R + G + MA ++E VG R + +Y+ TVG++ L YA
Sbjct: 198 NYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYA 257
Query: 157 LAGTPWGWRHMFGWATAPAVLQSLSLLFLPAG---------TDETATHKDLIPLQGGEAP 207
L W W + + P L L +P E D I + G+ P
Sbjct: 258 L--PHWRWLQLA--VSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLP 313
Query: 208 ---------------KLGPGRPRYSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLC 252
KL P SF DLFR +R RT + + L + Q +L
Sbjct: 314 PADLKMLSLEEDVTEKLSP-----SFADLFRT-PRLRKRTFILMYLWFTDSVLYQGLILH 367
Query: 253 YASTIFSSVGFHGGSSAVLASVGLGAVKVAATLTAMGLVDRAGR-----RALLLAGCALM 307
+T + L + V++ A+ +DR GR + LLAG A +
Sbjct: 368 MGAT---------SGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACL 418
Query: 308 AL 309
+
Sbjct: 419 VM 420
>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
sapiens]
Length = 554
Score = 57.4 bits (137), Expect = 3e-08
Identities = 75/302 (24%), Positives = 116/302 (38%), Gaps = 57/302 (18%)
Query: 37 QLDFGLSCLEQEFLVGSLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGLAG 96
+LD SCL FL GSL +G + D +GRK +LG+ LV + + +
Sbjct: 147 KLDLFQSCLNAGFLFGSLGVG---------YFADRFGRKLCLLGTVLVNAVSGVLMAFSP 197
Query: 97 SLAWLVLGRAVVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYA 156
+ ++L R + G + MA ++E VG R + +Y+ TVG++ L YA
Sbjct: 198 NYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYA 257
Query: 157 LAGTPWGWRHMFGWATAPAVLQSLSLLFLPAG---------TDETATHKDLIPLQGGEAP 207
L W W + + P L L +P E D I + G+ P
Sbjct: 258 L--PHWRWLQLA--VSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLP 313
Query: 208 ---------------KLGPGRPRYSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLC 252
KL P SF DLFR +R RT + + L + Q +L
Sbjct: 314 PADLKMLSLEEDVTEKLSP-----SFADLFRT-PRLRKRTFILMYLWFTDSVLYQGLILH 367
Query: 253 YASTIFSSVGFHGGSSAVLASVGLGAVKVAATLTAMGLVDRAGR-----RALLLAGCALM 307
+T + L + V++ A+ +DR GR + LLAG A +
Sbjct: 368 MGAT---------SGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACL 418
Query: 308 AL 309
+
Sbjct: 419 VM 420
Score = 30.4 bits (67), Expect = 4.3
Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 6/77 (7%)
Query: 433 LVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGLSWTFLLYGLTAVLGL-- 490
LV +E+YP +R C+S + ++ + W L L AVLGL
Sbjct: 451 LVNAELYPTFVRNLGVMVCSSLCDIGGIITPF----IVFRLREVWQALPLILFAVLGLLA 506
Query: 491 GFIYLFVPETKGQSLAE 507
+ L +PETKG +L E
Sbjct: 507 AGVTLLLPETKGVALPE 523
>gi|4507001 solute carrier family 22 member 2 [Homo sapiens]
Length = 555
Score = 57.0 bits (136), Expect = 4e-08
Identities = 32/127 (25%), Positives = 61/127 (48%), Gaps = 3/127 (2%)
Query: 39 DFGLSCLEQ---EFLVGSLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGLA 95
+F L C + S+ +G + S+ G++ D +GRK +L + L+ A + + ++
Sbjct: 138 EFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMAIS 197
Query: 96 GSLAWLVLGRAVVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNY 155
+ W+++ R + G + I ++E VG R R + Y+ TVG+L+ + Y
Sbjct: 198 PTYTWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVGIFYQVAYTVGLLVLAGVAY 257
Query: 156 ALAGTPW 162
AL W
Sbjct: 258 ALPHWRW 264
Score = 33.1 bits (74), Expect = 0.66
Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
Query: 430 VTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGLSWTFLLYGLTAVLG 489
+ LV +E+YP IR C+S + I+ + + I L +++G+ ++
Sbjct: 449 IVCLVNAELYPTFIRNLGVHICSSMCDIGGI-ITPFLVYRLTNIWLELPLMVFGVLGLVA 507
Query: 490 LGFIYLFVPETKGQSLAE 507
G + L +PETKG++L E
Sbjct: 508 GGLV-LLLPETKGKALPE 524
>gi|207447703 solute carrier family 2 (facilitated glucose/fructose
transporter), member 5 isoform 2 [Homo sapiens]
Length = 244
Score = 55.8 bits (133), Expect = 1e-07
Identities = 45/163 (27%), Positives = 77/163 (47%), Gaps = 20/163 (12%)
Query: 7 VLPLCASVSLLGG-LTFGYELAVISGALLPLQL---------------DFGLSCLEQEFL 50
VL L ++ G +GY +A ++ L +Q DF L+ L
Sbjct: 16 VLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLL-WSVT 74
Query: 51 VGSLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLG---LAGSLAWLVLGRAV 107
V G + SL+ G L++ +GRK A+L +N+ + ++ +G +A S +++ R +
Sbjct: 75 VSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLL 134
Query: 108 VGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLS 150
VG +SS +Y+ EL RG L + + ITVGIL++
Sbjct: 135 VGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVA 177
>gi|24497480 solute carrier family 22 member 6 isoform d [Homo
sapiens]
Length = 519
Score = 53.9 bits (128), Expect = 4e-07
Identities = 86/359 (23%), Positives = 147/359 (40%), Gaps = 39/359 (10%)
Query: 55 LLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISL 114
++G LL ++V G+L D GR++ ++ + L A + R + G A++
Sbjct: 142 MVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAG 201
Query: 115 SSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYALAGTPWGWRHMFGWATAP 174
S+ C E + R + +L ++G L + YA+ WRH+ +AP
Sbjct: 202 ISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVP----HWRHLQLLVSAP 257
Query: 175 AVLQSL-SLLFLPAGTDETATHK-DLIPLQGGEAPKLGPGRPRYSFLDLFRARDNMRGRT 232
+ S F+ + +++ + DL ++ R + L + R +++
Sbjct: 258 FFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKEL 317
Query: 233 TVGLGLVLFQQLTGQPNV----LCYASTIF-SSVGFHG--------GSSAVLASVGLGAV 279
T+G G +L P + LC + F +S ++G G S L V GAV
Sbjct: 318 TMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAV 377
Query: 280 KVAATLTAMGLVDRAGRR-----ALLLAGCALMALSV----SGIGLVSFAVPMDSGPSCL 330
+ A L +++ GRR ALLLAG ++ V I S AV G CL
Sbjct: 378 DLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSIVRTSLAV---LGKGCL 434
Query: 331 A-----VPNATGQ---TGLPGDSGLLQDSSLPPIPRTNEDQREPILSTAKKTKPHPRSG 381
A + TG+ T + + LL ++ P+P T +D T K+ +PR G
Sbjct: 435 AASFNCIFLYTGELYPTMIRAVTVLLPETLGQPLPDTVQDLESRWAPTQKEAGIYPRKG 493
>gi|213021148 SVOP-like isoform 1 [Homo sapiens]
Length = 492
Score = 50.8 bits (120), Expect = 3e-06
Identities = 43/168 (25%), Positives = 76/168 (45%), Gaps = 2/168 (1%)
Query: 19 GLTFGYELAVISGALLPLQLDFGLSCLEQEFLVGSLLLGALLASLVGGFLIDCYGRKQAI 78
G+ E+ +I+ ++ ++ L + + + G ++ S++ G L D YGR + +
Sbjct: 58 GVVEAMEIMLIAVVSPVIRCEWQLENWQVALVTTMVFFGYMVFSILFGLLADRYGRWKIL 117
Query: 79 LGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACCIYVSELVGPRQRGVLVSL 138
L S L SL A S W V R +VG +S S I +E + + RG ++ L
Sbjct: 118 LISFLWGAYFSLLTSFAPSYIWFVFLRTMVGCGVSGHSQG-LIIKTEFLPTKYRGYMLPL 176
Query: 139 YEAGITVGILLSYALNYALAGTPWGWRHMFGWATAPAVLQSLSLLFLP 186
+ G LL L + T GWR + A+ P ++ ++ F+P
Sbjct: 177 SQVFWLAGSLLIIGLASVIIPT-IGWRWLIRVASIPGIILIVAFKFIP 223
>gi|24497478 solute carrier family 22 member 6 isoform c [Homo
sapiens]
Length = 506
Score = 47.8 bits (112), Expect = 3e-05
Identities = 81/340 (23%), Positives = 140/340 (41%), Gaps = 39/340 (11%)
Query: 55 LLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISL 114
++G LL ++V G+L D GR++ ++ + L A + R + G A++
Sbjct: 142 MVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAG 201
Query: 115 SSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYALAGTPWGWRHMFGWATAP 174
S+ C E + R + +L ++G L + YA+ WRH+ +AP
Sbjct: 202 ISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVP----HWRHLQLLVSAP 257
Query: 175 AVLQSL-SLLFLPAGTDETATHK-DLIPLQGGEAPKLGPGRPRYSFLDLFRARDNMRGRT 232
+ S F+ + +++ + DL ++ R + L + R +++
Sbjct: 258 FFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKEL 317
Query: 233 TVGLGLVLFQQLTGQPNV----LCYASTIF-SSVGFHG--------GSSAVLASVGLGAV 279
T+G G +L P + LC + F +S ++G G S L V GAV
Sbjct: 318 TMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAV 377
Query: 280 KVAATLTAMGLVDRAGRR-----ALLLAGCALMALSV----SGIGLVSFAVPMDSGPSCL 330
+ A L +++ GRR ALLLAG ++ V I S AV G CL
Sbjct: 378 DLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSIVRTSLAV---LGKGCL 434
Query: 331 A-----VPNATGQ---TGLPGDSGLLQDSSLPPIPRTNED 362
A + TG+ T + + LL ++ P+P T +D
Sbjct: 435 AASFNCIFLYTGELYPTMIRAVTVLLPETLGQPLPDTVQD 474
>gi|24497476 solute carrier family 22 member 6 isoform b [Homo
sapiens]
Length = 550
Score = 47.4 bits (111), Expect = 3e-05
Identities = 72/301 (23%), Positives = 123/301 (40%), Gaps = 31/301 (10%)
Query: 55 LLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISL 114
++G LL ++V G+L D GR++ ++ + L A + R + G A++
Sbjct: 142 MVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAG 201
Query: 115 SSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYALAGTPWGWRHMFGWATAP 174
S+ C E + R + +L ++G L + YA+ WRH+ +AP
Sbjct: 202 ISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVP----HWRHLQLLVSAP 257
Query: 175 AVLQSL-SLLFLPAGTDETATHK-DLIPLQGGEAPKLGPGRPRYSFLDLFRARDNMRGRT 232
+ S F+ + +++ + DL ++ R + L + R +++
Sbjct: 258 FFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKEL 317
Query: 233 TVGLGLVLFQQLTGQPNV----LCYASTIF-SSVGFHG--------GSSAVLASVGLGAV 279
T+G G +L P + LC + F +S ++G G S L V GAV
Sbjct: 318 TMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAV 377
Query: 280 KVAATLTAMGLVDRAGRR-----ALLLAGCALMALSV----SGIGLVSFAVPMDSGPSCL 330
+ A L +++ GRR ALLLAG ++ V I S AV G CL
Sbjct: 378 DLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSIVRTSLAV---LGKGCL 434
Query: 331 A 331
A
Sbjct: 435 A 435
>gi|20070188 solute carrier family 22 member 6 isoform a [Homo
sapiens]
Length = 563
Score = 47.4 bits (111), Expect = 3e-05
Identities = 72/301 (23%), Positives = 123/301 (40%), Gaps = 31/301 (10%)
Query: 55 LLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISL 114
++G LL ++V G+L D GR++ ++ + L A + R + G A++
Sbjct: 142 MVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAG 201
Query: 115 SSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYALAGTPWGWRHMFGWATAP 174
S+ C E + R + +L ++G L + YA+ WRH+ +AP
Sbjct: 202 ISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVP----HWRHLQLLVSAP 257
Query: 175 AVLQSL-SLLFLPAGTDETATHK-DLIPLQGGEAPKLGPGRPRYSFLDLFRARDNMRGRT 232
+ S F+ + +++ + DL ++ R + L + R +++
Sbjct: 258 FFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKEL 317
Query: 233 TVGLGLVLFQQLTGQPNV----LCYASTIF-SSVGFHG--------GSSAVLASVGLGAV 279
T+G G +L P + LC + F +S ++G G S L V GAV
Sbjct: 318 TMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAV 377
Query: 280 KVAATLTAMGLVDRAGRR-----ALLLAGCALMALSV----SGIGLVSFAVPMDSGPSCL 330
+ A L +++ GRR ALLLAG ++ V I S AV G CL
Sbjct: 378 DLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSIVRTSLAV---LGKGCL 434
Query: 331 A 331
A
Sbjct: 435 A 435
>gi|24308167 SV2 related protein [Homo sapiens]
Length = 548
Score = 47.0 bits (110), Expect = 4e-05
Identities = 41/176 (23%), Positives = 79/176 (44%), Gaps = 5/176 (2%)
Query: 14 VSLLGGLTF---GYELAVISGALLPLQLDFGLSCLEQEFLVGSLLLGALLASLVGGFLID 70
+S+L GL + E+ ++S L ++ L + L + +G + +S + G + D
Sbjct: 86 LSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFVGMMSSSTLWGNISD 145
Query: 71 CYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACCIYVSELVGPR 130
YGRK + S L L + A +W+++ R +VGF I + +Y +E + +
Sbjct: 146 QYGRKTGLKISVLWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLY-AEFLPMK 204
Query: 131 QRGVLVSLYEAGITVGILLSYALNYALAGTPWGWRHMFGWATAPAVLQSLSLLFLP 186
R + L E +G + L + + GWR + + P +L ++ +LP
Sbjct: 205 ARAKCILLIEVFWAIGTVFEVVLAVFVMPS-LGWRWLLILSAVPLLLFAVLCFWLP 259
>gi|24497499 solute carrier family 22 member 8 [Homo sapiens]
Length = 542
Score = 45.8 bits (107), Expect = 1e-04
Identities = 71/292 (24%), Positives = 111/292 (38%), Gaps = 40/292 (13%)
Query: 47 QEFLVGSLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRA 106
+E + G L+ LV G L D +GR+ + S L+L A + + ++ R
Sbjct: 122 KEMAQSIFMAGILIGGLVLGDLSDRFGRRPILTCSYLLLAASGSGAAFSPTFPIYMVFRF 181
Query: 107 VVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYALAGTPWGWRH 166
+ GF IS +++ I E V R R ++ + T G + L YA+ W W
Sbjct: 182 LCGFGISGITLSTVILNVEWVPTRMRAIMSTALGYCYTFGQFILPGLAYAI--PQWRWLQ 239
Query: 167 -----------MFGWATAPAV------------LQSLSLLFLPAGTDETATHKDLIPLQG 203
+ W T ++ L+ L + + G E L L+
Sbjct: 240 LTVSIPFFVFFLSSWWTPESIRWLVLSGKSSKALKILRRVAVFNGKKEEGERLSLEELKL 299
Query: 204 GEAPKLGPGRPRYSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGF 263
++ + +Y+ DLFR M R T L L F TG Y S F
Sbjct: 300 NLQKEISLAKAKYTASDLFRI--PMLRRMTFCLSLAWF--ATG----FAYYSLAMGVEEF 351
Query: 264 HGGSSAVLASVGLGAVKVAATLTAMGLVDRAGRR-----ALLLAGCALMALS 310
G + + + G V V A + + GR ALLLAG A++AL+
Sbjct: 352 --GVNLYILQIIFGGVDVPAKFITILSLSYLGRHTTQAAALLLAGGAILALT 401
>gi|24497485 urate anion exchanger 1 isoform a [Homo sapiens]
Length = 553
Score = 42.0 bits (97), Expect = 0.001
Identities = 72/315 (22%), Positives = 117/315 (37%), Gaps = 49/315 (15%)
Query: 55 LLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISL 114
L G L+ + G D +GR+ + S L + A + L R ++ FA++
Sbjct: 153 LAGILVGAAACGPASDRFGRRLVLTWSYLQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAG 212
Query: 115 SSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYA---------LAGTPWGWR 165
M + E R R ++++L G + G L+ A+ Y + P+
Sbjct: 213 VMMNTGTLLMEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLC 272
Query: 166 HMFGWATAPAVLQSLSLLFLPAGTDET----------ATHKDLIP--LQGGEAPKLGPGR 213
++ W A + L+ L G E A L P L +L G+
Sbjct: 273 FLYSWWLAESARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQ 332
Query: 214 PRYSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGF-----HGGSS 268
P S L R +R RT + + LC+ + F+ G GS+
Sbjct: 333 PPASLGTLLR-MPGLRFRTCI--------------STLCWFAFGFTFFGLALDLQALGSN 377
Query: 269 AVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMALSVSGIGLVSFAVPMDSGPS 328
L + +G V + A + A+ L+ GRR L A L L + L + VP + G
Sbjct: 378 IFLLQMFIGVVDIPAKMGALLLLSHLGRRPTLAASLLLAGLCI----LANTLVPHEMG-- 431
Query: 329 CLAVPNATGQTGLPG 343
A+ +A GL G
Sbjct: 432 --ALRSALAVLGLGG 444
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.140 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,932,800
Number of Sequences: 37866
Number of extensions: 1033486
Number of successful extensions: 4985
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 100
Number of HSP's that attempted gapping in prelim test: 4476
Number of HSP's gapped (non-prelim): 527
length of query: 541
length of database: 18,247,518
effective HSP length: 107
effective length of query: 434
effective length of database: 14,195,856
effective search space: 6161001504
effective search space used: 6161001504
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.