Guide to the Human Genome
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Search of human proteins with 60218913

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|60218913 calcyclin binding protein isoform 2 [Homo sapiens]
         (185 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7656952 calcyclin binding protein isoform 1 [Homo sapiens]         374   e-104
gi|60218913 calcyclin binding protein isoform 2 [Homo sapiens]        374   e-104
gi|195963398 suppressor of G2 allele of SKP1 isoform a [Homo sap...    55   3e-08
gi|5730041 suppressor of G2 allele of SKP1 isoform b [Homo sapiens]    55   3e-08
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...    35   0.037
gi|75677576 dyslexia susceptibility 1 candidate 1 isoform c [Hom...    32   0.31 
gi|75677567 dyslexia susceptibility 1 candidate 1 isoform b [Hom...    32   0.31 
gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Hom...    32   0.31 
gi|113722133 senataxin [Homo sapiens]                                  31   0.69 
gi|207113147 heat shock transcription factor 2 isoform b [Homo s...    30   0.91 
gi|45827701 pad-1-like [Homo sapiens]                                  29   2.6  
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    28   3.4  
gi|169218146 PREDICTED: similar to neuron navigator 3, partial [...    28   4.5  
gi|84875541 cytochrome b5 reductase 4 [Homo sapiens]                   28   4.5  
gi|114155142 nuclear pore complex-associated protein TPR [Homo s...    28   4.5  
gi|120953251 neuron navigator 3 [Homo sapiens]                         28   4.5  
gi|110815834 F-box and WD-40 domain protein 10 [Homo sapiens]          28   4.5  
gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain...    28   5.9  

>gi|7656952 calcyclin binding protein isoform 1 [Homo sapiens]
          Length = 228

 Score =  374 bits (961), Expect = e-104
 Identities = 185/185 (100%), Positives = 185/185 (100%)

Query: 1   MQQKSQKKAELLDNEKPAAVVAPITTGYTVKISNYGWDQSDKFVKIYITLTGVHQVPTEN 60
           MQQKSQKKAELLDNEKPAAVVAPITTGYTVKISNYGWDQSDKFVKIYITLTGVHQVPTEN
Sbjct: 44  MQQKSQKKAELLDNEKPAAVVAPITTGYTVKISNYGWDQSDKFVKIYITLTGVHQVPTEN 103

Query: 61  VQVHFTERSFDLLVKNLNGKSYSMIVNNLLKPISVEGSSKKVKTDTVLILCRKKVENTRW 120
           VQVHFTERSFDLLVKNLNGKSYSMIVNNLLKPISVEGSSKKVKTDTVLILCRKKVENTRW
Sbjct: 104 VQVHFTERSFDLLVKNLNGKSYSMIVNNLLKPISVEGSSKKVKTDTVLILCRKKVENTRW 163

Query: 121 DYLTQVEKECKEKEKPSYDTETDPSEGLMNVLKKIYEDGDDDMKRTINKAWVESREKQAK 180
           DYLTQVEKECKEKEKPSYDTETDPSEGLMNVLKKIYEDGDDDMKRTINKAWVESREKQAK
Sbjct: 164 DYLTQVEKECKEKEKPSYDTETDPSEGLMNVLKKIYEDGDDDMKRTINKAWVESREKQAK 223

Query: 181 GDTEF 185
           GDTEF
Sbjct: 224 GDTEF 228


>gi|60218913 calcyclin binding protein isoform 2 [Homo sapiens]
          Length = 185

 Score =  374 bits (961), Expect = e-104
 Identities = 185/185 (100%), Positives = 185/185 (100%)

Query: 1   MQQKSQKKAELLDNEKPAAVVAPITTGYTVKISNYGWDQSDKFVKIYITLTGVHQVPTEN 60
           MQQKSQKKAELLDNEKPAAVVAPITTGYTVKISNYGWDQSDKFVKIYITLTGVHQVPTEN
Sbjct: 1   MQQKSQKKAELLDNEKPAAVVAPITTGYTVKISNYGWDQSDKFVKIYITLTGVHQVPTEN 60

Query: 61  VQVHFTERSFDLLVKNLNGKSYSMIVNNLLKPISVEGSSKKVKTDTVLILCRKKVENTRW 120
           VQVHFTERSFDLLVKNLNGKSYSMIVNNLLKPISVEGSSKKVKTDTVLILCRKKVENTRW
Sbjct: 61  VQVHFTERSFDLLVKNLNGKSYSMIVNNLLKPISVEGSSKKVKTDTVLILCRKKVENTRW 120

Query: 121 DYLTQVEKECKEKEKPSYDTETDPSEGLMNVLKKIYEDGDDDMKRTINKAWVESREKQAK 180
           DYLTQVEKECKEKEKPSYDTETDPSEGLMNVLKKIYEDGDDDMKRTINKAWVESREKQAK
Sbjct: 121 DYLTQVEKECKEKEKPSYDTETDPSEGLMNVLKKIYEDGDDDMKRTINKAWVESREKQAK 180

Query: 181 GDTEF 185
           GDTEF
Sbjct: 181 GDTEF 185


>gi|195963398 suppressor of G2 allele of SKP1 isoform a [Homo
           sapiens]
          Length = 365

 Score = 55.1 bits (131), Expect = 3e-08
 Identities = 47/170 (27%), Positives = 79/170 (46%), Gaps = 38/170 (22%)

Query: 35  YGWDQSDKFVKIYITLTGVHQVPTENVQVHFTERSFDLLVKNLNGKSYSMIVNNLLKPIS 94
           Y W Q++  V I + +  V +    +V V F+E+    LVK  +G+ Y++ +  LL PI 
Sbjct: 174 YDWYQTESQVVITLMIKNVQK---NDVNVEFSEKELSALVKLPSGEDYNLKL-ELLHPII 229

Query: 95  VEGSSKKVKTDTVLILCRKKVENTRWDYL------------------------------T 124
            E S+ KV   T + +  KK E  RW+ L                               
Sbjct: 230 PEQSTFKV-LSTKIEIKLKKPEAVRWEKLEGQGDVPTPKQFVADVKNLYPSSSPYTRNWD 288

Query: 125 QVEKECKEKEKPSYDTETDPSEGLMNVLKKIYEDGDDDMKRTINKAWVES 174
           ++  E KE+EK   + + +    L  + ++IY DG D++KR +NK+++ES
Sbjct: 289 KLVGEIKEEEK---NEKLEGDAALNRLFQQIYSDGSDEVKRAMNKSFMES 335


>gi|5730041 suppressor of G2 allele of SKP1 isoform b [Homo sapiens]
          Length = 333

 Score = 55.1 bits (131), Expect = 3e-08
 Identities = 47/170 (27%), Positives = 79/170 (46%), Gaps = 38/170 (22%)

Query: 35  YGWDQSDKFVKIYITLTGVHQVPTENVQVHFTERSFDLLVKNLNGKSYSMIVNNLLKPIS 94
           Y W Q++  V I + +  V +    +V V F+E+    LVK  +G+ Y++ +  LL PI 
Sbjct: 142 YDWYQTESQVVITLMIKNVQK---NDVNVEFSEKELSALVKLPSGEDYNLKL-ELLHPII 197

Query: 95  VEGSSKKVKTDTVLILCRKKVENTRWDYL------------------------------T 124
            E S+ KV   T + +  KK E  RW+ L                               
Sbjct: 198 PEQSTFKV-LSTKIEIKLKKPEAVRWEKLEGQGDVPTPKQFVADVKNLYPSSSPYTRNWD 256

Query: 125 QVEKECKEKEKPSYDTETDPSEGLMNVLKKIYEDGDDDMKRTINKAWVES 174
           ++  E KE+EK   + + +    L  + ++IY DG D++KR +NK+++ES
Sbjct: 257 KLVGEIKEEEK---NEKLEGDAALNRLFQQIYSDGSDEVKRAMNKSFMES 303


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score = 35.0 bits (79), Expect = 0.037
 Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 15/109 (13%)

Query: 79  GKSYSMIVNN---LLKPISVEGSSKKVKT----DTVLILCRKKVENTRWDYLTQVEKECK 131
           G+S S++  +   +LK I V+ +   VK       V++  R K+E    D    ++ E +
Sbjct: 561 GRSVSLVGEDERKMLKEI-VKAAKAPVKARILPQDVILKFRDKIEKMEKDVYAVLQLEAE 619

Query: 132 EKEKPSYDTETDPSEGLMNVLKKIYEDGDDDMKRTINKAWVESREKQAK 180
           EK       E   SE  +N  K++ E G + + +   ++W +++E++ K
Sbjct: 620 EK-------EMQQSEAQINTAKRLLEKGKEAVVQEPERSWFQTKEERKK 661


>gi|75677576 dyslexia susceptibility 1 candidate 1 isoform c [Homo
           sapiens]
          Length = 381

 Score = 32.0 bits (71), Expect = 0.31
 Identities = 31/112 (27%), Positives = 49/112 (43%), Gaps = 24/112 (21%)

Query: 30  VKISNYGWDQSDKFVKIYITLTGV-----HQVPTEN-VQVHFTERSFDLLVKNLNGKSYS 83
           +++S+Y W Q+   V + + L GV         TEN ++V+F    F+            
Sbjct: 3   LQVSDYSWQQTKTAVFLSLPLKGVCVRDTDVFCTENYLKVNFPPFLFEAF---------- 52

Query: 84  MIVNNLLKPISVEGSSKKVKTDTVLILCRKKVENTRWDYL--TQVEKECKEK 133
                L  PI  E S  K+  DT++    KK E   W+ L  T V+KE  ++
Sbjct: 53  -----LYAPIDDESSKAKIGNDTIVFTLYKK-EAAMWETLSVTGVDKEMMQR 98


>gi|75677567 dyslexia susceptibility 1 candidate 1 isoform b [Homo
           sapiens]
          Length = 376

 Score = 32.0 bits (71), Expect = 0.31
 Identities = 31/112 (27%), Positives = 49/112 (43%), Gaps = 24/112 (21%)

Query: 30  VKISNYGWDQSDKFVKIYITLTGV-----HQVPTEN-VQVHFTERSFDLLVKNLNGKSYS 83
           +++S+Y W Q+   V + + L GV         TEN ++V+F    F+            
Sbjct: 3   LQVSDYSWQQTKTAVFLSLPLKGVCVRDTDVFCTENYLKVNFPPFLFEAF---------- 52

Query: 84  MIVNNLLKPISVEGSSKKVKTDTVLILCRKKVENTRWDYL--TQVEKECKEK 133
                L  PI  E S  K+  DT++    KK E   W+ L  T V+KE  ++
Sbjct: 53  -----LYAPIDDESSKAKIGNDTIVFTLYKK-EAAMWETLSVTGVDKEMMQR 98


>gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Homo
           sapiens]
          Length = 420

 Score = 32.0 bits (71), Expect = 0.31
 Identities = 31/112 (27%), Positives = 49/112 (43%), Gaps = 24/112 (21%)

Query: 30  VKISNYGWDQSDKFVKIYITLTGV-----HQVPTEN-VQVHFTERSFDLLVKNLNGKSYS 83
           +++S+Y W Q+   V + + L GV         TEN ++V+F    F+            
Sbjct: 3   LQVSDYSWQQTKTAVFLSLPLKGVCVRDTDVFCTENYLKVNFPPFLFEAF---------- 52

Query: 84  MIVNNLLKPISVEGSSKKVKTDTVLILCRKKVENTRWDYL--TQVEKECKEK 133
                L  PI  E S  K+  DT++    KK E   W+ L  T V+KE  ++
Sbjct: 53  -----LYAPIDDESSKAKIGNDTIVFTLYKK-EAAMWETLSVTGVDKEMMQR 98


>gi|113722133 senataxin [Homo sapiens]
          Length = 2677

 Score = 30.8 bits (68), Expect = 0.69
 Identities = 17/64 (26%), Positives = 32/64 (50%), Gaps = 2/64 (3%)

Query: 75   KNLNGKSYSMIVNNLLKPISVEGSSKKVKTDTVLILC--RKKVENTRWDYLTQVEKECKE 132
            K + G  Y ++  N  K  S E S+ K+K + VL+       V+      + + +++CK+
Sbjct: 1971 KTIVGLLYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKD 2030

Query: 133  KEKP 136
            K+ P
Sbjct: 2031 KKNP 2034


>gi|207113147 heat shock transcription factor 2 isoform b [Homo
           sapiens]
          Length = 518

 Score = 30.4 bits (67), Expect = 0.91
 Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 5/55 (9%)

Query: 59  ENVQVHFTERSF----DLLVKNLNGKSYSMIVNNLLKPISVEGSSKKVKTDTVLI 109
           E+ Q   + R F    DLLV + N K      NN+++P+S EG   K K D  LI
Sbjct: 372 EDFQAMLSGRQFSIDPDLLVDSEN-KGLETTKNNVVQPVSEEGRKSKSKPDKQLI 425


>gi|45827701 pad-1-like [Homo sapiens]
          Length = 2298

 Score = 28.9 bits (63), Expect = 2.6
 Identities = 17/65 (26%), Positives = 29/65 (44%), Gaps = 1/65 (1%)

Query: 81  SYSMIVNNLLKPISVEGSSKKVKTDTVLILCRKKVENTRWDYLTQVEKECKEKEKPSYDT 140
           SY+   N+L+  I    ++ ++   TV +L      +  WDY+T+  +EC    K  Y  
Sbjct: 407 SYTQSGNSLISAIKENRNASEI-VKTVNLLITSLSTDFLWDYMTRCFEECFRPVKQRYSV 465

Query: 141 ETDPS 145
               S
Sbjct: 466 RNSVS 470


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 28.5 bits (62), Expect = 3.4
 Identities = 19/64 (29%), Positives = 32/64 (50%), Gaps = 4/64 (6%)

Query: 116 ENTRWDYLTQVEKECKEKEKPSYDTETD--PSEGLMNVLKKIYEDGDDDMKRTINKAWVE 173
           E   WD   ++EK+ +E+EK ++D E      E +    KK+ E  +++M R   +   E
Sbjct: 557 EQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE--EEEMMREQEEKMQE 614

Query: 174 SREK 177
             EK
Sbjct: 615 QEEK 618


>gi|169218146 PREDICTED: similar to neuron navigator 3, partial
           [Homo sapiens]
          Length = 733

 Score = 28.1 bits (61), Expect = 4.5
 Identities = 16/48 (33%), Positives = 25/48 (52%), Gaps = 3/48 (6%)

Query: 110 LCRKKVENTRWDYLTQVEKECKEKEKPSYDTETDPSEGLMNVLKKIYE 157
           L + + E+  ++  T  ++    K  P  DTE DP   LMN+L K+ E
Sbjct: 659 LLQLRPEDVGYESCTSTKEATTSKHIPQTDTEGDP---LMNMLMKLQE 703


>gi|84875541 cytochrome b5 reductase 4 [Homo sapiens]
          Length = 521

 Score = 28.1 bits (61), Expect = 4.5
 Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 7/120 (5%)

Query: 6   QKKAELLDNEKPAAVVAPITTGYTVKISNYGWDQSDKFVKIYITLTGVHQVPTENVQVHF 65
           +++ ++L+   P + V            +Y W Q+D  V I I  T    +  +++ V  
Sbjct: 141 EEEKKVLNGMLPKSQVTDTLAKEGPSYPSYDWFQTDSLVTIAI-YTKQKDINLDSIIVDH 199

Query: 66  TERSF--DLLVKNLNGKSYSMIVNNLLKPISVEGSSKKVKTDTVLILCRKKVENTRWDYL 123
              SF  + ++K+     +  + + + +  SV       K + VL    +K ENT WD+L
Sbjct: 200 QNDSFRAETIIKDCLYLIHIGLSHEVQEDFSVRVVESVGKIEIVL----QKKENTSWDFL 255


>gi|114155142 nuclear pore complex-associated protein TPR [Homo
            sapiens]
          Length = 2363

 Score = 28.1 bits (61), Expect = 4.5
 Identities = 26/101 (25%), Positives = 47/101 (46%), Gaps = 12/101 (11%)

Query: 94   SVEGSSKKVKTDTVLILCRKKVE---NTRWDYLTQVEKECKEKEKPSYDTETDPSEGL-- 148
            S+E S  K K  T  +  RK +E       ++ TQ+EK+  E EK   + + D    +  
Sbjct: 971  SLEESLNKEKQVTEEV--RKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIES 1028

Query: 149  ----MNVLKKIYEDGDDDMKRTINKAWVE-SREKQAKGDTE 184
                ++ LKK      ++++  + +A    S E+QA+ D +
Sbjct: 1029 MEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQ 1069


>gi|120953251 neuron navigator 3 [Homo sapiens]
          Length = 2363

 Score = 28.1 bits (61), Expect = 4.5
 Identities = 16/48 (33%), Positives = 25/48 (52%), Gaps = 3/48 (6%)

Query: 110  LCRKKVENTRWDYLTQVEKECKEKEKPSYDTETDPSEGLMNVLKKIYE 157
            L + + E+  ++  T  ++    K  P  DTE DP   LMN+L K+ E
Sbjct: 2289 LLQLRPEDVGYESCTSTKEATTSKHIPQTDTEGDP---LMNMLMKLQE 2333


>gi|110815834 F-box and WD-40 domain protein 10 [Homo sapiens]
          Length = 1051

 Score = 28.1 bits (61), Expect = 4.5
 Identities = 16/60 (26%), Positives = 30/60 (50%), Gaps = 6/60 (10%)

Query: 95  VEGSSKKVKTDTVLILCRKKVENTRWDYLTQVEKECKEKEKPSYDTETDPSEGLMNVLKK 154
           ++G+   V T++ +++ +   E+ +W Y  +  K+ K KEK     E      LM +L K
Sbjct: 665 IQGNRMVVNTESNVLMFQ--FEHIKWQYAVEKTKQKKNKEK----EEEKEENSLMEILSK 718


>gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
           isoform a [Homo sapiens]
          Length = 903

 Score = 27.7 bits (60), Expect = 5.9
 Identities = 13/37 (35%), Positives = 20/37 (54%)

Query: 148 LMNVLKKIYEDGDDDMKRTINKAWVESREKQAKGDTE 184
           L +++K    DG  D K+ + KAW +   K AK + E
Sbjct: 128 LDSLMKGQLRDGRQDSKKQLEKAWKDYEAKMAKLEKE 164


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.128    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,713,984
Number of Sequences: 37866
Number of extensions: 278184
Number of successful extensions: 757
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 745
Number of HSP's gapped (non-prelim): 22
length of query: 185
length of database: 18,247,518
effective HSP length: 96
effective length of query: 89
effective length of database: 14,612,382
effective search space: 1300501998
effective search space used: 1300501998
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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