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Search of human proteins with 5901970
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5901970 histamine N-methyltransferase isoform 1 [Homo
sapiens]
(292 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5901970 histamine N-methyltransferase isoform 1 [Homo sapiens] 595 e-170
gi|66932965 histamine N-methyltransferase isoform 3 [Homo sapiens] 130 2e-30
gi|66932963 histamine N-methyltransferase isoform 2 [Homo sapiens] 99 6e-21
gi|27734911 DAZ interacting protein 1-like [Homo sapiens] 31 1.1
gi|33188445 microfilament and actin filament cross-linker protei... 30 3.3
gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens] 30 3.3
gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens] 30 3.3
gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens] 30 3.3
gi|42544224 N-myc downstream-regulated gene 2 isoform b [Homo sa... 29 4.3
gi|42544222 N-myc downstream-regulated gene 2 isoform a [Homo sa... 29 4.3
gi|42544220 N-myc downstream-regulated gene 2 isoform a [Homo sa... 29 4.3
gi|42544218 N-myc downstream-regulated gene 2 isoform b [Homo sa... 29 4.3
gi|42544216 N-myc downstream-regulated gene 2 isoform a [Homo sa... 29 4.3
gi|10280620 N-myc downstream-regulated gene 2 isoform b [Homo sa... 29 4.3
gi|42544213 N-myc downstream-regulated gene 2 isoform b [Homo sa... 29 4.3
gi|42544211 N-myc downstream-regulated gene 2 isoform a [Homo sa... 29 4.3
gi|150456465 tetratricopeptide repeat domain 9 [Homo sapiens] 29 4.3
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 29 4.3
gi|38570156 5'-nucleotidase, cytosolic II-like 1 protein [Homo s... 28 9.5
gi|94721321 coiled-coil domain containing 11 [Homo sapiens] 28 9.5
gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo ... 28 9.5
>gi|5901970 histamine N-methyltransferase isoform 1 [Homo sapiens]
Length = 292
Score = 595 bits (1533), Expect = e-170
Identities = 292/292 (100%), Positives = 292/292 (100%)
Query: 1 MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG 60
MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG
Sbjct: 1 MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG 60
Query: 61 GGAGEIDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETS 120
GGAGEIDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETS
Sbjct: 61 GGAGEIDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETS 120
Query: 121 SEYQSRMLEKKELQKWDFIHMIQMLYYVKDIPATLKFFHSLLGTNAKMLIIVVSGSSGWD 180
SEYQSRMLEKKELQKWDFIHMIQMLYYVKDIPATLKFFHSLLGTNAKMLIIVVSGSSGWD
Sbjct: 121 SEYQSRMLEKKELQKWDFIHMIQMLYYVKDIPATLKFFHSLLGTNAKMLIIVVSGSSGWD 180
Query: 181 KLWKKYGSRFPQDDLCQYITSDDLTQMLDNLGLKYECYDLLSTMDISDCFIDGNENGDLL 240
KLWKKYGSRFPQDDLCQYITSDDLTQMLDNLGLKYECYDLLSTMDISDCFIDGNENGDLL
Sbjct: 181 KLWKKYGSRFPQDDLCQYITSDDLTQMLDNLGLKYECYDLLSTMDISDCFIDGNENGDLL 240
Query: 241 WDFLTETCNFNATAPPDLRAELGKDLQEPEFSAKKEGKVLFNNTLSFIVIEA 292
WDFLTETCNFNATAPPDLRAELGKDLQEPEFSAKKEGKVLFNNTLSFIVIEA
Sbjct: 241 WDFLTETCNFNATAPPDLRAELGKDLQEPEFSAKKEGKVLFNNTLSFIVIEA 292
>gi|66932965 histamine N-methyltransferase isoform 3 [Homo
sapiens]
Length = 126
Score = 130 bits (326), Expect = 2e-30
Identities = 63/63 (100%), Positives = 63/63 (100%)
Query: 1 MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG 60
MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG
Sbjct: 1 MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG 60
Query: 61 GGA 63
GGA
Sbjct: 61 GGA 63
>gi|66932963 histamine N-methyltransferase isoform 2 [Homo
sapiens]
Length = 51
Score = 98.6 bits (244), Expect = 6e-21
Identities = 46/46 (100%), Positives = 46/46 (100%)
Query: 1 MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGR 46
MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGR
Sbjct: 1 MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGR 46
>gi|27734911 DAZ interacting protein 1-like [Homo sapiens]
Length = 767
Score = 31.2 bits (69), Expect = 1.1
Identities = 16/47 (34%), Positives = 24/47 (51%)
Query: 89 EPSAEQIAKYKELVAKTSNLENVKFAWHKETSSEYQSRMLEKKELQK 135
E S E + + +EL A E K W ++ ++ M EKKELQ+
Sbjct: 311 EESEEWLRQARELQALREKTEIQKTEWKRKVKELHEEHMAEKKELQE 357
>gi|33188445 microfilament and actin filament cross-linker protein
isoform a [Homo sapiens]
Length = 5430
Score = 29.6 bits (65), Expect = 3.3
Identities = 28/118 (23%), Positives = 53/118 (44%), Gaps = 8/118 (6%)
Query: 128 LEKKELQKWDFIHMIQMLYYVKDIPATLKFFHSLLGTNAKMLIIVVSGSSGWDKLWKKYG 187
++KK KW H++++ ++ D+ L+ H+L+ + I + G + +
Sbjct: 79 VQKKTFTKWVNKHLMKVRKHINDLYEDLRDGHNLISLLEVLSGIKLPREKGRMRFHRLQN 138
Query: 188 SRFPQDDLCQ------YITSDDLTQMLDNLGLKYECYDLLSTMDISDCFIDGNENGDL 239
+ D L Q I +DD+T L L + ++ ISD +I G E+GD+
Sbjct: 139 VQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGL-IWTIILHFQISDIYISG-ESGDM 194
>gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 29.6 bits (65), Expect = 3.3
Identities = 16/61 (26%), Positives = 31/61 (50%), Gaps = 3/61 (4%)
Query: 72 SKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKF---AWHKETSSEYQSRML 128
S+++ V N E V + E++ K KE++ + K+ A HKE +++ Q ++
Sbjct: 852 SQIEVMAAEVAKNKESVNKAQEEVTKQKEVITAQDTVIKAKYAEVAKHKEQNNDSQLKIK 911
Query: 129 E 129
E
Sbjct: 912 E 912
>gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 29.6 bits (65), Expect = 3.3
Identities = 16/61 (26%), Positives = 31/61 (50%), Gaps = 3/61 (4%)
Query: 72 SKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKF---AWHKETSSEYQSRML 128
S+++ V N E V + E++ K KE++ + K+ A HKE +++ Q ++
Sbjct: 852 SQIEVMAAEVAKNKESVNKAQEEVTKQKEVITAQDTVIKAKYAEVAKHKEQNNDSQLKIK 911
Query: 129 E 129
E
Sbjct: 912 E 912
>gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 29.6 bits (65), Expect = 3.3
Identities = 16/61 (26%), Positives = 31/61 (50%), Gaps = 3/61 (4%)
Query: 72 SKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKF---AWHKETSSEYQSRML 128
S+++ V N E V + E++ K KE++ + K+ A HKE +++ Q ++
Sbjct: 852 SQIEVMAAEVAKNKESVNKAQEEVTKQKEVITAQDTVIKAKYAEVAKHKEQNNDSQLKIK 911
Query: 129 E 129
E
Sbjct: 912 E 912
>gi|42544224 N-myc downstream-regulated gene 2 isoform b [Homo
sapiens]
Length = 357
Score = 29.3 bits (64), Expect = 4.3
Identities = 11/47 (23%), Positives = 24/47 (51%)
Query: 70 ILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWH 116
+ S + G + E + ++E I KY+ ++ NL+N++ W+
Sbjct: 175 LTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWN 221
>gi|42544222 N-myc downstream-regulated gene 2 isoform a [Homo
sapiens]
Length = 371
Score = 29.3 bits (64), Expect = 4.3
Identities = 11/47 (23%), Positives = 24/47 (51%)
Query: 70 ILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWH 116
+ S + G + E + ++E I KY+ ++ NL+N++ W+
Sbjct: 189 LTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWN 235
>gi|42544220 N-myc downstream-regulated gene 2 isoform a [Homo
sapiens]
Length = 371
Score = 29.3 bits (64), Expect = 4.3
Identities = 11/47 (23%), Positives = 24/47 (51%)
Query: 70 ILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWH 116
+ S + G + E + ++E I KY+ ++ NL+N++ W+
Sbjct: 189 LTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWN 235
>gi|42544218 N-myc downstream-regulated gene 2 isoform b [Homo
sapiens]
Length = 357
Score = 29.3 bits (64), Expect = 4.3
Identities = 11/47 (23%), Positives = 24/47 (51%)
Query: 70 ILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWH 116
+ S + G + E + ++E I KY+ ++ NL+N++ W+
Sbjct: 175 LTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWN 221
>gi|42544216 N-myc downstream-regulated gene 2 isoform a [Homo
sapiens]
Length = 371
Score = 29.3 bits (64), Expect = 4.3
Identities = 11/47 (23%), Positives = 24/47 (51%)
Query: 70 ILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWH 116
+ S + G + E + ++E I KY+ ++ NL+N++ W+
Sbjct: 189 LTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWN 235
>gi|10280620 N-myc downstream-regulated gene 2 isoform b [Homo
sapiens]
Length = 357
Score = 29.3 bits (64), Expect = 4.3
Identities = 11/47 (23%), Positives = 24/47 (51%)
Query: 70 ILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWH 116
+ S + G + E + ++E I KY+ ++ NL+N++ W+
Sbjct: 175 LTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWN 221
>gi|42544213 N-myc downstream-regulated gene 2 isoform b [Homo
sapiens]
Length = 357
Score = 29.3 bits (64), Expect = 4.3
Identities = 11/47 (23%), Positives = 24/47 (51%)
Query: 70 ILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWH 116
+ S + G + E + ++E I KY+ ++ NL+N++ W+
Sbjct: 175 LTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWN 221
>gi|42544211 N-myc downstream-regulated gene 2 isoform a [Homo
sapiens]
Length = 371
Score = 29.3 bits (64), Expect = 4.3
Identities = 11/47 (23%), Positives = 24/47 (51%)
Query: 70 ILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWH 116
+ S + G + E + ++E I KY+ ++ NL+N++ W+
Sbjct: 189 LTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWN 235
>gi|150456465 tetratricopeptide repeat domain 9 [Homo sapiens]
Length = 222
Score = 29.3 bits (64), Expect = 4.3
Identities = 33/123 (26%), Positives = 49/123 (39%), Gaps = 5/123 (4%)
Query: 25 HSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIGGGAGEIDLQILSKVQAQYPGVCIN 84
H + Q Q + DKK IG+ E+K L G E D + S A PG
Sbjct: 58 HEFKSQGAQCYKDKKFREAIGKYHRALLELKGLLPPPGERERDSRPASPAGALKPGRLSE 117
Query: 85 NEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETSSEYQSRMLEKKELQKWDFIHMIQM 144
+ A +I Y L A E V + E EY ++L KKE + + ++ +
Sbjct: 118 EQSKTVEAIEIDCYNSLAACLLQAELVNY----ERVKEYCLKVL-KKEGENFKALYRSGV 172
Query: 145 LYY 147
+Y
Sbjct: 173 AFY 175
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 29.3 bits (64), Expect = 4.3
Identities = 20/75 (26%), Positives = 39/75 (52%), Gaps = 6/75 (8%)
Query: 104 KTSNLENVKFAWHKETSSEYQSR-MLEKKELQKWDFIHMIQMLYYVKDIPATLKFFHSLL 162
+TS+ +N+ A + + + R ++KK KW H+I+ ++ D+ L+ H+L+
Sbjct: 18 RTSSEDNLYLAVLRASEGKKDERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLI 77
Query: 163 GTNAKMLIIVVSGSS 177
L+ V+SG S
Sbjct: 78 S-----LLEVLSGDS 87
>gi|38570156 5'-nucleotidase, cytosolic II-like 1 protein [Homo
sapiens]
Length = 455
Score = 28.1 bits (61), Expect = 9.5
Identities = 16/63 (25%), Positives = 29/63 (46%), Gaps = 12/63 (19%)
Query: 147 YVKDIPATLKFFHSLLGTNAKMLIIVVSGSSGWDKLWKKYGSRFPQDDLCQYITSDDLTQ 206
Y+ P ++K + L K+L+++ S S + +L LC+YI +D T
Sbjct: 193 YLHSCPESVKKWLRQLKNAGKILLLITSSHSDYCRL------------LCEYILGNDFTD 240
Query: 207 MLD 209
+ D
Sbjct: 241 LFD 243
>gi|94721321 coiled-coil domain containing 11 [Homo sapiens]
Length = 514
Score = 28.1 bits (61), Expect = 9.5
Identities = 21/70 (30%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 66 IDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETSSEYQS 125
+D + ++++ G IN E E+ K +EL+A N + KET E +
Sbjct: 75 LDSLVRARIKDAVQGFIINIE------ERRNKLRELLALEENEYFTEMQLKKETIEEKKD 128
Query: 126 RMLEKKELQK 135
RM EK +L K
Sbjct: 129 RMREKTKLLK 138
>gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo
sapiens]
Length = 1386
Score = 28.1 bits (61), Expect = 9.5
Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 3/60 (5%)
Query: 81 VCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWH---KETSSEYQSRMLEKKELQKWD 137
V + NE ++I+K + AK+ + EN K K+ S ++QS + E++ L W+
Sbjct: 489 VIVENESYVNLKKKISKRYDWQAKSVHAENGKICKQFRMKQASRQFQSILQERQSLPAWE 548
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,599,728
Number of Sequences: 37866
Number of extensions: 445624
Number of successful extensions: 1119
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1103
Number of HSP's gapped (non-prelim): 22
length of query: 292
length of database: 18,247,518
effective HSP length: 101
effective length of query: 191
effective length of database: 14,423,052
effective search space: 2754802932
effective search space used: 2754802932
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.