Guide to the Human Genome
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Search of human proteins with 5803056

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5803056 lysosomal multispanning membrane protein 5 [Homo
sapiens]
         (262 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5803056 lysosomal multispanning membrane protein 5 [Homo sapi...   520   e-148
gi|7661916 lysosomal protein transmembrane 4 alpha [Homo sapiens]      74   1e-13
gi|30409982 lysosomal associated transmembrane protein 4 beta [H...    52   5e-07
gi|32698902 transmembrane protein 61 [Homo sapiens]                    33   0.33 
gi|160420295 hypothetical protein LOC85459 [Homo sapiens]              31   0.96 
gi|16933559 protocadherin LKC precursor [Homo sapiens]                 30   1.6  
gi|106067657 luteinizing hormone/choriogonadotropin receptor pre...    30   2.8  
gi|52317239 olfactory receptor, family 4, subfamily D, member 10...    30   2.8  
gi|64085121 thyroid stimulating hormone receptor isoform 1 precu...    29   3.6  
gi|194733735 transient receptor potential cation channel, subfam...    28   6.2  
gi|4507687 transient receptor potential cation channel, subfamil...    28   6.2  
gi|239746918 PREDICTED: hypothetical protein [Homo sapiens]            28   6.2  
gi|9966761 choroideremia isoform a [Homo sapiens]                      28   8.1  
gi|31542327 solute carrier family 22, member 16 [Homo sapiens]         28   8.1  

>gi|5803056 lysosomal multispanning membrane protein 5 [Homo
           sapiens]
          Length = 262

 Score =  520 bits (1340), Expect = e-148
 Identities = 262/262 (100%), Positives = 262/262 (100%)

Query: 1   MDPRLSTVRQTCCCFNVRIATTALAIYHVIMSVLLFIEHSVEVAHGKASCKLSQMGYLRI 60
           MDPRLSTVRQTCCCFNVRIATTALAIYHVIMSVLLFIEHSVEVAHGKASCKLSQMGYLRI
Sbjct: 1   MDPRLSTVRQTCCCFNVRIATTALAIYHVIMSVLLFIEHSVEVAHGKASCKLSQMGYLRI 60

Query: 61  ADLISSFLLITMLFIISLSLLIGVVKNREKYLLPFLSLQIMDYLLCLLTLLGSYIELPAY 120
           ADLISSFLLITMLFIISLSLLIGVVKNREKYLLPFLSLQIMDYLLCLLTLLGSYIELPAY
Sbjct: 61  ADLISSFLLITMLFIISLSLLIGVVKNREKYLLPFLSLQIMDYLLCLLTLLGSYIELPAY 120

Query: 121 LKLASRSRASSSKFPLMTLQLLDFCLSILTLCSSYMEVPTYLNFKSMNHMNYLPSQEDMP 180
           LKLASRSRASSSKFPLMTLQLLDFCLSILTLCSSYMEVPTYLNFKSMNHMNYLPSQEDMP
Sbjct: 121 LKLASRSRASSSKFPLMTLQLLDFCLSILTLCSSYMEVPTYLNFKSMNHMNYLPSQEDMP 180

Query: 181 HNQFIKMMIIFSIAFITVLIFKVYMFKCVWRCYRLIKCMNSVEEKRNSKMLQKVVLPSYE 240
           HNQFIKMMIIFSIAFITVLIFKVYMFKCVWRCYRLIKCMNSVEEKRNSKMLQKVVLPSYE
Sbjct: 181 HNQFIKMMIIFSIAFITVLIFKVYMFKCVWRCYRLIKCMNSVEEKRNSKMLQKVVLPSYE 240

Query: 241 EALSLPSKTPEGGPAPPPYSEV 262
           EALSLPSKTPEGGPAPPPYSEV
Sbjct: 241 EALSLPSKTPEGGPAPPPYSEV 262


>gi|7661916 lysosomal protein transmembrane 4 alpha [Homo sapiens]
          Length = 233

 Score = 73.9 bits (180), Expect = 1e-13
 Identities = 64/260 (24%), Positives = 105/260 (40%), Gaps = 61/260 (23%)

Query: 12  CCCFNVRIATTALAIYHVIMSVLLFIEHSVEVAHGKASCKLSQMGYLRIADLISS----- 66
           C C +VR  T  L  +++++++L+ I  +VEV H   S     + Y  I +  SS     
Sbjct: 20  CGCCHVRTGTIILGTWYMVVNLLMAILLTVEVTHPN-SMPAVNIQYEVIGNYYSSERMAD 78

Query: 67  -----FLLITMLFIISLSLLIGVVKNREKYLLPFLSLQIMDYLLCLLTLLGSYIELPAYL 121
                F +  ++FIIS  L+ G +  +  +L+PF   +                      
Sbjct: 79  NACVLFAVSVLMFIISSMLVYGAISYQVGWLIPFFCYR---------------------- 116

Query: 122 KLASRSRASSSKFPLMTLQLLDFCLSILTLCSSYMEVPTYLNFKSMNHMNYLPSQEDMPH 181
                              L DF LS L   SS   +P    +  ++ +   P ++D+  
Sbjct: 117 -------------------LFDFVLSCLVAISSLTYLPRIKEY--LDQLPDFPYKDDLLA 155

Query: 182 NQFIKMMIIFSIAFITVLIFKVYMFKCVWRCYRLIKCMN--SVEEKRNSKMLQKVVLPSY 239
                ++ I  + F   +IFK Y+  CVW CY+ I   N   +      +   + VLP+Y
Sbjct: 156 LDSSCLLFIVLVFFALFIIFKAYLINCVWNCYKYINNRNVPEIAVYPAFEAPPQYVLPTY 215

Query: 240 EEALSLPSKTPEGGPAPPPY 259
           E A+ +P K P     PPPY
Sbjct: 216 EMAVKMPEKEP-----PPPY 230


>gi|30409982 lysosomal associated transmembrane protein 4 beta [Homo
           sapiens]
          Length = 317

 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 60/257 (23%), Positives = 105/257 (40%), Gaps = 58/257 (22%)

Query: 12  CCCFNVRIATTALAIYHVIMS-VLLFIEHSVEVAHGKASCKLSQMGYLRIADLISSFLLI 70
           C C +VR  T  L ++++I++ V+L I  S      + +   S++G          F  +
Sbjct: 107 CLCCHVRTGTILLGVWYLIINAVVLLILLSALADPDQYNFSSSELG--------GDFEFM 158

Query: 71  ---TMLFIISLSLLIGVVKNREKYLLPFLSLQIMDYLLCLLTLLGSYIELPAYLKLASRS 127
               M   I++SLL+                     L+C +   G+Y +  A++      
Sbjct: 159 DDANMCIAIAISLLM--------------------ILICAMATYGAYKQRAAWI------ 192

Query: 128 RASSSKFPLMTLQLLDFCLSILTLCSSYMEVPTYLNFKSMNHMNYLPSQEDMPHNQFIKM 187
                  P    Q+ DF L++L   +  +   +   +      N+ P ++D+       +
Sbjct: 193 ------IPFFCYQIFDFALNMLVAITVLIYPNSIQEYIRQLPPNF-PYRDDVMSVNPTCL 245

Query: 188 MIIFSIAFITVLIFKVYMFKCVWRCYRLIKCMNS----VEEKRNSKMLQKVVLPSYEEA- 242
           ++I  +    +L FK Y+  CVW CYR I   NS    V    N      V+LP Y++A 
Sbjct: 246 VLIILLFISIILTFKGYLISCVWNCYRYINGRNSSDVLVYVTSND---TTVLLPPYDDAT 302

Query: 243 LSLPSKTPEGGPAPPPY 259
           ++  +K P     PPPY
Sbjct: 303 VNGAAKEP-----PPPY 314


>gi|32698902 transmembrane protein 61 [Homo sapiens]
          Length = 210

 Score = 32.7 bits (73), Expect = 0.33
 Identities = 16/36 (44%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 224 EKRNSKMLQKVVLPSYEEALSLPSKTPEGGPAPPPY 259
           EK + +  + V +P+YEEA+S P    EG P PP Y
Sbjct: 117 EKESCRTPKVVDIPTYEEAVSFP--VAEGPPTPPAY 150


>gi|160420295 hypothetical protein LOC85459 [Homo sapiens]
          Length = 2601

 Score = 31.2 bits (69), Expect = 0.96
 Identities = 30/137 (21%), Positives = 55/137 (40%), Gaps = 7/137 (5%)

Query: 1    MDPRLSTVRQTCCCFNVRIATTALAIYHVIMSVLLFIEHSVEVAHGKASCKLSQMGYLRI 60
            ++P++       C   V + T+  A Y +      + E+S E    K + KLSQ+G   +
Sbjct: 2312 INPQVEETDSRLCVRTVEMGTSIQAPYSLTTQNEKYFENSAETDIPKITKKLSQLGESEL 2371

Query: 61   ADLISSFLLITMLFIISLSLLIGVVKNREKYLLPFLSLQIMDYLLCLLTL-------LGS 113
                 SF L + + +       G+++  E  L+      I +     LTL          
Sbjct: 2372 FASSGSFSLQSSIPVWETETGHGIMEEPELTLISTTDTSIAEMDFANLTLEEKSENEAKC 2431

Query: 114  YIELPAYLKLASRSRAS 130
            + ++  +L L S + AS
Sbjct: 2432 FFQVSEFLPLVSATEAS 2448


>gi|16933559 protocadherin LKC precursor [Homo sapiens]
          Length = 1310

 Score = 30.4 bits (67), Expect = 1.6
 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 1/55 (1%)

Query: 175  SQEDMPHNQFIKMMIIFSIAFITVLIFKVYMFKCVWRCY-RLIKCMNSVEEKRNS 228
            SQE     Q I ++I   +A + VL+     F CV + Y R ++ M + +E R +
Sbjct: 1143 SQESDLSKQLISVIIGLGVALLLVLVIMTMAFVCVRKSYNRKLQAMKAAKEARKT 1197


>gi|106067657 luteinizing hormone/choriogonadotropin receptor
           precursor [Homo sapiens]
          Length = 699

 Score = 29.6 bits (65), Expect = 2.8
 Identities = 15/63 (23%), Positives = 35/63 (55%), Gaps = 2/63 (3%)

Query: 98  LQIMDYLLCLLTLLGSYIELPAYLKLASRSRASSSKFPLMTLQLLDFCLSILTLCSSYME 157
           L+++ +L+ +L ++G+   L  ++ L SR + +  +F +  L   DFC+ +  L  + ++
Sbjct: 362 LRVLIWLINILAIMGNMTVL--FVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVD 419

Query: 158 VPT 160
             T
Sbjct: 420 SQT 422


>gi|52317239 olfactory receptor, family 4, subfamily D, member 10
           [Homo sapiens]
          Length = 311

 Score = 29.6 bits (65), Expect = 2.8
 Identities = 24/91 (26%), Positives = 46/91 (50%), Gaps = 8/91 (8%)

Query: 80  LLIGVVKNREKYLLPFLSLQIMDYLLCLLTLLGSYIELPAYLKLASRSRASSSKFPLM-T 138
           + +G+ +NRE  L+ FL L     L+ + TLLG+ + +   + +   SR  +  + L+  
Sbjct: 13  IFLGLTQNREVSLVLFLFL----LLVYVTTLLGNLLIM---VTVTCESRLHTPMYFLLHN 65

Query: 139 LQLLDFCLSILTLCSSYMEVPTYLNFKSMNH 169
           L + D C S +T+    +++ +     S NH
Sbjct: 66  LSIADICFSSITVPKVLVDLLSERKTISFNH 96


>gi|64085121 thyroid stimulating hormone receptor isoform 1
           precursor [Homo sapiens]
          Length = 764

 Score = 29.3 bits (64), Expect = 3.6
 Identities = 17/73 (23%), Positives = 38/73 (52%), Gaps = 2/73 (2%)

Query: 92  LLPFLSLQIMDYLLCLLTLLGSYIELPAYLKLASRSRASSSKFPLMTLQLLDFCLSILTL 151
           ++ +  L+I+ + + LL LLG+   L   + L S  + +  +F +  L   DFC+ +  L
Sbjct: 411 IMGYKFLRIVVWFVSLLALLGNVFVL--LILLTSHYKLNVPRFLMCNLAFADFCMGMYLL 468

Query: 152 CSSYMEVPTYLNF 164
             + +++ T+  +
Sbjct: 469 LIASVDLYTHSEY 481


>gi|194733735 transient receptor potential cation channel, subfamily
           C, member 3 isoform a [Homo sapiens]
          Length = 921

 Score = 28.5 bits (62), Expect = 6.2
 Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 6/69 (8%)

Query: 95  FLSLQIMDYLLCLLTLLGSYIELPAYLKLASRSRASSSKFPLMTLQLLDFCLSILTLCSS 154
           +LSL   D +L  L L           KLA+  +   + +  +++Q  DF + +L LC  
Sbjct: 299 YLSLSSEDPVLTALELSNELA------KLANIEKEFKNDYRKLSMQCKDFVVGVLDLCRD 352

Query: 155 YMEVPTYLN 163
             EV   LN
Sbjct: 353 SEEVEAILN 361


>gi|4507687 transient receptor potential cation channel, subfamily
           C, member 3 isoform b [Homo sapiens]
          Length = 848

 Score = 28.5 bits (62), Expect = 6.2
 Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 6/69 (8%)

Query: 95  FLSLQIMDYLLCLLTLLGSYIELPAYLKLASRSRASSSKFPLMTLQLLDFCLSILTLCSS 154
           +LSL   D +L  L L           KLA+  +   + +  +++Q  DF + +L LC  
Sbjct: 226 YLSLSSEDPVLTALELSNELA------KLANIEKEFKNDYRKLSMQCKDFVVGVLDLCRD 279

Query: 155 YMEVPTYLN 163
             EV   LN
Sbjct: 280 SEEVEAILN 288


>gi|239746918 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 264

 Score = 28.5 bits (62), Expect = 6.2
 Identities = 18/76 (23%), Positives = 34/76 (44%), Gaps = 5/76 (6%)

Query: 188 MIIFSIAFITVLIFK-VYMFKCVWRCYRLIKCMNSVEEKRNS----KMLQKVVLPSYEEA 242
           M I+   +I V ++  VY+  CV+ C  +  C+ +   +R +    + L++   P+  E 
Sbjct: 169 MCIYMYVYIHVCVYVYVYIHVCVYTCMCICVCVYTFRRRRRAPPGRQRLEERTGPAGPEG 228

Query: 243 LSLPSKTPEGGPAPPP 258
              P        +PPP
Sbjct: 229 KEQPPALASQTSSPPP 244


>gi|9966761 choroideremia isoform a [Homo sapiens]
          Length = 653

 Score = 28.1 bits (61), Expect = 8.1
 Identities = 17/62 (27%), Positives = 28/62 (45%), Gaps = 1/62 (1%)

Query: 127 SRASSSKFPLMTLQLLDFCLSILTLCSSYMEVPT-YLNFKSMNHMNYLPSQEDMPHNQFI 185
           SRA       +T+      +  LT C  Y + P  Y  ++ +    YL +Q+  P+ Q+I
Sbjct: 277 SRADVFNSKQLTMVEKRMLMKFLTFCMEYEKYPDEYKGYEEITFYEYLKTQKLTPNLQYI 336

Query: 186 KM 187
            M
Sbjct: 337 VM 338


>gi|31542327 solute carrier family 22, member 16 [Homo sapiens]
          Length = 577

 Score = 28.1 bits (61), Expect = 8.1
 Identities = 16/49 (32%), Positives = 27/49 (55%)

Query: 37  IEHSVEVAHGKASCKLSQMGYLRIADLISSFLLITMLFIISLSLLIGVV 85
           I  S+ V  G   C+L+ +      DL S ++ I  LF+ +++LL GV+
Sbjct: 472 IVRSLAVGSGSMVCRLASILAPFSVDLSSIWIFIPQLFVGTMALLSGVL 520


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.139    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,149,415
Number of Sequences: 37866
Number of extensions: 352760
Number of successful extensions: 2061
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2049
Number of HSP's gapped (non-prelim): 17
length of query: 262
length of database: 18,247,518
effective HSP length: 100
effective length of query: 162
effective length of database: 14,460,918
effective search space: 2342668716
effective search space used: 2342668716
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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