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Search of human proteins with 56549093
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56549093 B-cell receptor-associated protein BAP29 isoform a
[Homo sapiens]
(348 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56549093 B-cell receptor-associated protein BAP29 isoform a [... 693 0.0
gi|56549091 B-cell receptor-associated protein BAP29 isoform b [... 452 e-127
gi|32171186 B-cell receptor-associated protein 31 isoform b [Hom... 224 7e-59
gi|213511508 B-cell receptor-associated protein 31 isoform a [Ho... 224 7e-59
gi|213511012 B-cell receptor-associated protein 31 isoform b [Ho... 224 7e-59
gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens] 44 3e-04
gi|51317384 GLE1 RNA export mediator homolog isoform 1 [Homo sap... 43 4e-04
gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo sa... 43 4e-04
gi|75750468 spectrin domain with coiled-coils 1 NSP5a3a [Homo sa... 43 4e-04
gi|75750472 spectrin domain with coiled-coils 1 NSP5b3b [Homo sa... 43 4e-04
gi|75750466 spectrin domain with coiled-coils 1 NSP5b3a [Homo sa... 43 4e-04
gi|4557627 GLE1 RNA export mediator homolog isoform 2 [Homo sapi... 43 4e-04
gi|134152708 arginine and glutamate rich 1 [Homo sapiens] 43 4e-04
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 43 5e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 43 5e-04
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 43 5e-04
gi|148746195 trichohyalin [Homo sapiens] 42 6e-04
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 42 6e-04
gi|115511012 coiled-coil domain containing 136 [Homo sapiens] 40 0.002
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 40 0.003
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 40 0.003
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 40 0.003
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 40 0.003
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 40 0.003
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 40 0.003
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 40 0.003
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 40 0.003
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 40 0.003
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 40 0.003
gi|187761324 shootin1 isoform a [Homo sapiens] 40 0.003
>gi|56549093 B-cell receptor-associated protein BAP29 isoform a
[Homo sapiens]
Length = 348
Score = 693 bits (1789), Expect = 0.0
Identities = 348/348 (100%), Positives = 348/348 (100%)
Query: 1 MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI 60
MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI
Sbjct: 1 MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI 60
Query: 61 VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL 120
VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL
Sbjct: 61 VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL 120
Query: 121 VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL 180
VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL
Sbjct: 121 VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL 180
Query: 181 VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSSFGEFLSK 240
VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSSFGEFLSK
Sbjct: 181 VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSSFGEFLSK 240
Query: 241 RSHKNGSIGKQTGSRKGSFRKRQQEKTVNFIKDTCNILCQNDNFVMLASRKFKFRKMHYD 300
RSHKNGSIGKQTGSRKGSFRKRQQEKTVNFIKDTCNILCQNDNFVMLASRKFKFRKMHYD
Sbjct: 241 RSHKNGSIGKQTGSRKGSFRKRQQEKTVNFIKDTCNILCQNDNFVMLASRKFKFRKMHYD 300
Query: 301 RFVIFLMPHIGCIVMALSKYLMMFQIYCKVCIPALKKNISMLNTIFTY 348
RFVIFLMPHIGCIVMALSKYLMMFQIYCKVCIPALKKNISMLNTIFTY
Sbjct: 301 RFVIFLMPHIGCIVMALSKYLMMFQIYCKVCIPALKKNISMLNTIFTY 348
>gi|56549091 B-cell receptor-associated protein BAP29 isoform b
[Homo sapiens]
Length = 241
Score = 452 bits (1164), Expect = e-127
Identities = 230/230 (100%), Positives = 230/230 (100%)
Query: 1 MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI 60
MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI
Sbjct: 1 MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI 60
Query: 61 VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL 120
VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL
Sbjct: 61 VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL 120
Query: 121 VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL 180
VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL
Sbjct: 121 VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL 180
Query: 181 VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQ 230
VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQ
Sbjct: 181 VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQ 230
>gi|32171186 B-cell receptor-associated protein 31 isoform b [Homo
sapiens]
Length = 246
Score = 224 bits (572), Expect = 7e-59
Identities = 118/235 (50%), Positives = 164/235 (69%), Gaps = 6/235 (2%)
Query: 1 MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI 60
M+LQW AVATFLYAE+ ++L+ C+PFI P+RWQKIF + + ++ N F+ +I++L+
Sbjct: 1 MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV 60
Query: 61 VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL 120
+L +DAVRE+RKY V T + + + P A EH MKLFR+QRNLYI+GFSL +LRRL
Sbjct: 61 LLVIDAVREIRKYDDV-TEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRL 119
Query: 121 VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHG-----KDEECVLEA 175
VTLI+Q A L++ K QAE+ ++AAKK+MEEN++LK+ G + E LE
Sbjct: 120 VTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEE 179
Query: 176 ENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQ 230
EN+ L D +KLK EL T L KA+N V+ M+ QSE L+KEYD+LL+EH++LQ
Sbjct: 180 ENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQ 234
>gi|213511508 B-cell receptor-associated protein 31 isoform a [Homo
sapiens]
Length = 313
Score = 224 bits (572), Expect = 7e-59
Identities = 118/235 (50%), Positives = 164/235 (69%), Gaps = 6/235 (2%)
Query: 1 MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI 60
M+LQW AVATFLYAE+ ++L+ C+PFI P+RWQKIF + + ++ N F+ +I++L+
Sbjct: 68 MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV 127
Query: 61 VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL 120
+L +DAVRE+RKY V T + + + P A EH MKLFR+QRNLYI+GFSL +LRRL
Sbjct: 128 LLVIDAVREIRKYDDV-TEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRL 186
Query: 121 VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHG-----KDEECVLEA 175
VTLI+Q A L++ K QAE+ ++AAKK+MEEN++LK+ G + E LE
Sbjct: 187 VTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEE 246
Query: 176 ENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQ 230
EN+ L D +KLK EL T L KA+N V+ M+ QSE L+KEYD+LL+EH++LQ
Sbjct: 247 ENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQ 301
>gi|213511012 B-cell receptor-associated protein 31 isoform b [Homo
sapiens]
Length = 246
Score = 224 bits (572), Expect = 7e-59
Identities = 118/235 (50%), Positives = 164/235 (69%), Gaps = 6/235 (2%)
Query: 1 MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFNVWGKIATFWNKAFLTIIILLI 60
M+LQW AVATFLYAE+ ++L+ C+PFI P+RWQKIF + + ++ N F+ +I++L+
Sbjct: 1 MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILV 60
Query: 61 VLFLDAVREVRKYSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRL 120
+L +DAVRE+RKY V T + + + P A EH MKLFR+QRNLYI+GFSL +LRRL
Sbjct: 61 LLVIDAVREIRKYDDV-TEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRL 119
Query: 121 VTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHG-----KDEECVLEA 175
VTLI+Q A L++ K QAE+ ++AAKK+MEEN++LK+ G + E LE
Sbjct: 120 VTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEE 179
Query: 176 ENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQ 230
EN+ L D +KLK EL T L KA+N V+ M+ QSE L+KEYD+LL+EH++LQ
Sbjct: 180 ENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQ 234
>gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]
Length = 636
Score = 43.5 bits (101), Expect = 3e-04
Identities = 41/159 (25%), Positives = 70/159 (44%), Gaps = 17/159 (10%)
Query: 120 LVTLITQLAKELSN-KGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEEC------- 171
L TL QL KE K L E ++AA++ EEN +LK++L S+G E
Sbjct: 208 LQTLCEQLRKENEALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGNKEGASGRPGSP 267
Query: 172 VLEAENKKLVEDQEKLKTELRKTSD--ALSKAQNDVMEMKMQSERL---SKEYDQLLKEH 226
+E KK V Q++ K + AL A+ V ++ Q L +K++DQ H
Sbjct: 268 KMEGTGKKAVAGQQQASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQ----H 323
Query: 227 SELQHSSFGEFLSKRSHKNGSIGKQTGSRKGSFRKRQQE 265
+ + +++ K + KQ + ++Q++
Sbjct: 324 FRSMKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRD 362
>gi|51317384 GLE1 RNA export mediator homolog isoform 1 [Homo
sapiens]
Length = 698
Score = 43.1 bits (100), Expect = 4e-04
Identities = 39/155 (25%), Positives = 72/155 (46%), Gaps = 11/155 (7%)
Query: 73 YSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRLVTLITQLAKELS 132
+S + T D +HT+ + +S R + + G + LV R T +L +E
Sbjct: 95 FSPASPATPNGTKGKDESQHTESMVLQSSRGIKVEGCVRMYELVHRMKGTEGLRLWQEEQ 154
Query: 133 NKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEEC--VLEAENKKLVEDQEKLKTE 190
+ V + +E ++ K+F E E LK H + ++ V+E +++ + QEKLK E
Sbjct: 155 ERKV-QALSEMASEQLKRFDEWKE-----LKQHKEFQDLREVMEKSSREALGHQEKLKAE 208
Query: 191 LRKTSDALSKAQNDVMEMKM---QSERLSKEYDQL 222
R + L+ + + ++ + ERL KE Q+
Sbjct: 209 HRHRAKILNLKLREAEQQRVKQAEQERLRKEEGQI 243
>gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo
sapiens]
Length = 987
Score = 43.1 bits (100), Expect = 4e-04
Identities = 40/177 (22%), Positives = 78/177 (44%), Gaps = 26/177 (14%)
Query: 123 LITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEE------CVLEAE 176
L + K + K +L+T + A++ +ENEKL +L+ K+EE ++E E
Sbjct: 327 LTAENEKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQERVKNEEPTTQEGKIIELE 386
Query: 177 NK-------------KLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLL 223
K KL+ Q++L LRK + A + +K ++E+L+ E+ +L
Sbjct: 387 QKCTGILEQGRFEREKLLNIQQQLTCSLRKVEEENQGALEMIKRLKEENEKLN-EFLELE 445
Query: 224 KEHSELQHSSFGE---FLSKRSHKNGSIGKQTGSRKGSFRKRQQEKTVNFIKDTCNI 277
+ ++ + + E L +NGS+ +G +K + V ++C +
Sbjct: 446 RHNNNMMAKTLEECRVTLEGLKMENGSLKSHL---QGEKQKATEASAVEQTAESCEV 499
>gi|75750468 spectrin domain with coiled-coils 1 NSP5a3a [Homo
sapiens]
Length = 709
Score = 43.1 bits (100), Expect = 4e-04
Identities = 40/177 (22%), Positives = 78/177 (44%), Gaps = 26/177 (14%)
Query: 123 LITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEE------CVLEAE 176
L + K + K +L+T + A++ +ENEKL +L+ K+EE ++E E
Sbjct: 327 LTAENEKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQERVKNEEPTTQEGKIIELE 386
Query: 177 NK-------------KLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLL 223
K KL+ Q++L LRK + A + +K ++E+L+ E+ +L
Sbjct: 387 QKCTGILEQGRFEREKLLNIQQQLTCSLRKVEEENQGALEMIKRLKEENEKLN-EFLELE 445
Query: 224 KEHSELQHSSFGE---FLSKRSHKNGSIGKQTGSRKGSFRKRQQEKTVNFIKDTCNI 277
+ ++ + + E L +NGS+ +G +K + V ++C +
Sbjct: 446 RHNNNMMAKTLEECRVTLEGLKMENGSLKSHL---QGEKQKATEASAVEQTAESCEV 499
>gi|75750472 spectrin domain with coiled-coils 1 NSP5b3b [Homo
sapiens]
Length = 1068
Score = 43.1 bits (100), Expect = 4e-04
Identities = 40/177 (22%), Positives = 78/177 (44%), Gaps = 26/177 (14%)
Query: 123 LITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEE------CVLEAE 176
L + K + K +L+T + A++ +ENEKL +L+ K+EE ++E E
Sbjct: 408 LTAENEKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQERVKNEEPTTQEGKIIELE 467
Query: 177 NK-------------KLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLL 223
K KL+ Q++L LRK + A + +K ++E+L+ E+ +L
Sbjct: 468 QKCTGILEQGRFEREKLLNIQQQLTCSLRKVEEENQGALEMIKRLKEENEKLN-EFLELE 526
Query: 224 KEHSELQHSSFGE---FLSKRSHKNGSIGKQTGSRKGSFRKRQQEKTVNFIKDTCNI 277
+ ++ + + E L +NGS+ +G +K + V ++C +
Sbjct: 527 RHNNNMMAKTLEECRVTLEGLKMENGSLKSHL---QGEKQKATEASAVEQTAESCEV 580
>gi|75750466 spectrin domain with coiled-coils 1 NSP5b3a [Homo
sapiens]
Length = 790
Score = 43.1 bits (100), Expect = 4e-04
Identities = 40/177 (22%), Positives = 78/177 (44%), Gaps = 26/177 (14%)
Query: 123 LITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEE------CVLEAE 176
L + K + K +L+T + A++ +ENEKL +L+ K+EE ++E E
Sbjct: 408 LTAENEKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQERVKNEEPTTQEGKIIELE 467
Query: 177 NK-------------KLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLL 223
K KL+ Q++L LRK + A + +K ++E+L+ E+ +L
Sbjct: 468 QKCTGILEQGRFEREKLLNIQQQLTCSLRKVEEENQGALEMIKRLKEENEKLN-EFLELE 526
Query: 224 KEHSELQHSSFGE---FLSKRSHKNGSIGKQTGSRKGSFRKRQQEKTVNFIKDTCNI 277
+ ++ + + E L +NGS+ +G +K + V ++C +
Sbjct: 527 RHNNNMMAKTLEECRVTLEGLKMENGSLKSHL---QGEKQKATEASAVEQTAESCEV 580
>gi|4557627 GLE1 RNA export mediator homolog isoform 2 [Homo
sapiens]
Length = 659
Score = 43.1 bits (100), Expect = 4e-04
Identities = 39/155 (25%), Positives = 72/155 (46%), Gaps = 11/155 (7%)
Query: 73 YSSVHTIEKSSTSRPDAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRLVTLITQLAKELS 132
+S + T D +HT+ + +S R + + G + LV R T +L +E
Sbjct: 95 FSPASPATPNGTKGKDESQHTESMVLQSSRGIKVEGCVRMYELVHRMKGTEGLRLWQEEQ 154
Query: 133 NKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEEC--VLEAENKKLVEDQEKLKTE 190
+ V + +E ++ K+F E E LK H + ++ V+E +++ + QEKLK E
Sbjct: 155 ERKV-QALSEMASEQLKRFDEWKE-----LKQHKEFQDLREVMEKSSREALGHQEKLKAE 208
Query: 191 LRKTSDALSKAQNDVMEMKM---QSERLSKEYDQL 222
R + L+ + + ++ + ERL KE Q+
Sbjct: 209 HRHRAKILNLKLREAEQQRVKQAEQERLRKEEGQI 243
>gi|134152708 arginine and glutamate rich 1 [Homo sapiens]
Length = 273
Score = 43.1 bits (100), Expect = 4e-04
Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 9/108 (8%)
Query: 116 VLRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
VLRR+ + K+L + + QAE AA+K EE E+ KR ++ E +LE
Sbjct: 157 VLRRVEEAKRIMEKQLLEELERQRQAE---LAAQKAREEEERAKR------EELERILEE 207
Query: 176 ENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLL 223
N+K+ E Q KL E + + K + M+++ + +R KE +++
Sbjct: 208 NNRKIAEAQAKLAEEQLRIVEEQRKIHEERMKLEQERQRQQKEEQKII 255
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 42.7 bits (99), Expect = 5e-04
Identities = 31/127 (24%), Positives = 62/127 (48%), Gaps = 2/127 (1%)
Query: 117 LRRLVTLITQLAKELSN-KGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
L+ L L KE + + ++T EN+ + K +ENE L + + S + + EA
Sbjct: 521 LQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEA 580
Query: 176 ENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQH-SSF 234
K + ++ + L +++TS LSK + + ++K + E ++ ++ + +EL H
Sbjct: 581 RVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKE 640
Query: 235 GEFLSKR 241
E L K+
Sbjct: 641 NELLQKK 647
Score = 38.5 bits (88), Expect = 0.009
Identities = 33/110 (30%), Positives = 58/110 (52%), Gaps = 7/110 (6%)
Query: 127 LAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECV--LEAENKKLVEDQ 184
L K+++N + + E + + EN KLK+ L S + LE EN +L D+
Sbjct: 644 LQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQL--DE 701
Query: 185 EKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSSF 234
E L ELR+ ++L A + +++++++ L E +Q LK+ EL +SF
Sbjct: 702 ENL--ELRRNVESLKCASMKMAQLQLENKELESEKEQ-LKKGLELLKASF 748
Score = 35.0 bits (79), Expect = 0.100
Identities = 36/160 (22%), Positives = 74/160 (46%), Gaps = 26/160 (16%)
Query: 129 KELSNKGV--LKTQAENTNKAAKKFME---ENEKLKRILKSHGKDEECV------LEAEN 177
KE KG+ LK + T + + EN++L++ L++ K + + LE EN
Sbjct: 734 KEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMEN 793
Query: 178 KKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSS--FG 235
+ L ++ E+LK +S L + + + ++ ++ +L K+ QL KE+ L+ +
Sbjct: 794 QTLQKNLEELKI----SSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKD 849
Query: 236 EFLSKRSHKNGSIGKQTGSRKGSFRKRQQEKTVNFIKDTC 275
L + + K G++ K+ + K + K++C
Sbjct: 850 TTLEENNVKIGNLEKE---------NKTLSKEIGIYKESC 880
Score = 33.5 bits (75), Expect = 0.29
Identities = 40/177 (22%), Positives = 76/177 (42%), Gaps = 19/177 (10%)
Query: 130 ELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVL--EAENKKLVEDQEKL 187
EL++ +LK + EN + + E+L+ + S + +L E EN++L + E L
Sbjct: 456 ELTSSRLLKLEMEN-----QSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEIL 510
Query: 188 KTELRKTSDALSKAQN---DVMEMKMQSERLSKEYDQLLKEHSELQHSSFGEFLSKRSHK 244
+ E+ + +L QN D+M+ K Q E+ + L+E+SE Q + + H
Sbjct: 511 ENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTI----ETLRENSERQIKILEQ---ENEHL 563
Query: 245 NGSIG--KQTGSRKGSFRKRQQEKTVNFIKDTCNILCQNDNFVMLASRKFKFRKMHY 299
N ++ +Q R + EK + ++ + + R+ K HY
Sbjct: 564 NQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHY 620
Score = 33.1 bits (74), Expect = 0.38
Identities = 46/190 (24%), Positives = 77/190 (40%), Gaps = 35/190 (18%)
Query: 123 LITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLK-----------RILKSHG--KDE 169
LI Q + E N+ V+K + E+ ++++EKL+ ++ HG K
Sbjct: 1129 LIQQSSLENENESVIK-EREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSA 1187
Query: 170 ECVLEAENKKL-------------VEDQEK-LKTELRKTSDALSKAQNDVMEMKM---QS 212
LE E++ L +ED EK LK E K + E K ++
Sbjct: 1188 HKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGEN 1247
Query: 213 ERLSKEYDQLLKEHSELQ--HSSFGEFLSKRSHKNGSIGKQTGSRKGSFRKRQQEKTVNF 270
+RL+ Y QLLKE LQ H + L+ + + + K + +Q + T
Sbjct: 1248 DRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQY--QQLDITSTK 1305
Query: 271 IKDTCNILCQ 280
+ + C +L Q
Sbjct: 1306 LNNQCELLSQ 1315
Score = 32.3 bits (72), Expect = 0.65
Identities = 45/183 (24%), Positives = 76/183 (41%), Gaps = 40/183 (21%)
Query: 126 QLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSH--GKDEECVLEAENKKLVED 183
+L K L + L Q E+ K + EEN +L+R ++S + L+ ENK+L +
Sbjct: 674 KLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESE 733
Query: 184 QEKLK-------TELRKT-----------------SDALSKAQNDVMEMKMQSERLSKEY 219
+E+LK +KT L + + +++ + + L E
Sbjct: 734 KEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMEN 793
Query: 220 DQLLKEHSELQHSSFGEFLSKRSHKNGSIGKQTGS--------RKGSFRKRQQEKTVNFI 271
L K EL+ SS + L + +N S+ ++T K + R RQQ + I
Sbjct: 794 QTLQKNLEELKISS--KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE----I 847
Query: 272 KDT 274
KDT
Sbjct: 848 KDT 850
Score = 32.3 bits (72), Expect = 0.65
Identities = 19/78 (24%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
Query: 153 EENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQS 212
E E + +LK KD +E N L +++ LKT+L++ + Q ++ ++ Q+
Sbjct: 1033 ESQETTRELLKV--KDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQT 1090
Query: 213 ERLSKEYDQLLKEHSELQ 230
L ++ L ++++LQ
Sbjct: 1091 VSLQEQNTTLQTQNAKLQ 1108
Score = 32.0 bits (71), Expect = 0.84
Identities = 34/145 (23%), Positives = 61/145 (42%), Gaps = 19/145 (13%)
Query: 119 RLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENK 178
RL+ + A + K LKTQ + + L+R S +++ L+ +N
Sbjct: 1047 RLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSL-QEQNTTLQTQNA 1105
Query: 179 KLVEDQEKLKTE----LRKTSDAL---SKAQNDVMEMKMQSERLSKEYDQLLKEHSEL-- 229
KL + L ++ + + + L S +N+ + + E L YD L+K+H +L
Sbjct: 1106 KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLEL 1165
Query: 230 ----QHSSFGEFLSKR-----SHKN 245
Q S + +SK +HKN
Sbjct: 1166 LHERQASEYESLISKHGTLKSAHKN 1190
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 42.7 bits (99), Expect = 5e-04
Identities = 31/127 (24%), Positives = 62/127 (48%), Gaps = 2/127 (1%)
Query: 117 LRRLVTLITQLAKELSN-KGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
L+ L L KE + + ++T EN+ + K +ENE L + + S + + EA
Sbjct: 521 LQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEA 580
Query: 176 ENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQH-SSF 234
K + ++ + L +++TS LSK + + ++K + E ++ ++ + +EL H
Sbjct: 581 RVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKE 640
Query: 235 GEFLSKR 241
E L K+
Sbjct: 641 NELLQKK 647
Score = 38.5 bits (88), Expect = 0.009
Identities = 33/110 (30%), Positives = 58/110 (52%), Gaps = 7/110 (6%)
Query: 127 LAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECV--LEAENKKLVEDQ 184
L K+++N + + E + + EN KLK+ L S + LE EN +L D+
Sbjct: 644 LQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQL--DE 701
Query: 185 EKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSSF 234
E L ELR+ ++L A + +++++++ L E +Q LK+ EL +SF
Sbjct: 702 ENL--ELRRNVESLKCASMKMAQLQLENKELESEKEQ-LKKGLELLKASF 748
Score = 35.0 bits (79), Expect = 0.100
Identities = 36/160 (22%), Positives = 74/160 (46%), Gaps = 26/160 (16%)
Query: 129 KELSNKGV--LKTQAENTNKAAKKFME---ENEKLKRILKSHGKDEECV------LEAEN 177
KE KG+ LK + T + + EN++L++ L++ K + + LE EN
Sbjct: 734 KEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMEN 793
Query: 178 KKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSS--FG 235
+ L ++ E+LK +S L + + + ++ ++ +L K+ QL KE+ L+ +
Sbjct: 794 QTLQKNLEELKI----SSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKD 849
Query: 236 EFLSKRSHKNGSIGKQTGSRKGSFRKRQQEKTVNFIKDTC 275
L + + K G++ K+ + K + K++C
Sbjct: 850 TTLEENNVKIGNLEKE---------NKTLSKEIGIYKESC 880
Score = 33.5 bits (75), Expect = 0.29
Identities = 40/177 (22%), Positives = 76/177 (42%), Gaps = 19/177 (10%)
Query: 130 ELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVL--EAENKKLVEDQEKL 187
EL++ +LK + EN + + E+L+ + S + +L E EN++L + E L
Sbjct: 456 ELTSSRLLKLEMEN-----QSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEIL 510
Query: 188 KTELRKTSDALSKAQN---DVMEMKMQSERLSKEYDQLLKEHSELQHSSFGEFLSKRSHK 244
+ E+ + +L QN D+M+ K Q E+ + L+E+SE Q + + H
Sbjct: 511 ENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTI----ETLRENSERQIKILEQ---ENEHL 563
Query: 245 NGSIG--KQTGSRKGSFRKRQQEKTVNFIKDTCNILCQNDNFVMLASRKFKFRKMHY 299
N ++ +Q R + EK + ++ + + R+ K HY
Sbjct: 564 NQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHY 620
Score = 33.1 bits (74), Expect = 0.38
Identities = 46/190 (24%), Positives = 77/190 (40%), Gaps = 35/190 (18%)
Query: 123 LITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLK-----------RILKSHG--KDE 169
LI Q + E N+ V+K + E+ ++++EKL+ ++ HG K
Sbjct: 1128 LIQQSSLENENESVIK-EREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSA 1186
Query: 170 ECVLEAENKKL-------------VEDQEK-LKTELRKTSDALSKAQNDVMEMKM---QS 212
LE E++ L +ED EK LK E K + E K ++
Sbjct: 1187 HKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGEN 1246
Query: 213 ERLSKEYDQLLKEHSELQ--HSSFGEFLSKRSHKNGSIGKQTGSRKGSFRKRQQEKTVNF 270
+RL+ Y QLLKE LQ H + L+ + + + K + +Q + T
Sbjct: 1247 DRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQY--QQLDITSTK 1304
Query: 271 IKDTCNILCQ 280
+ + C +L Q
Sbjct: 1305 LNNQCELLSQ 1314
Score = 32.3 bits (72), Expect = 0.65
Identities = 45/183 (24%), Positives = 76/183 (41%), Gaps = 40/183 (21%)
Query: 126 QLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSH--GKDEECVLEAENKKLVED 183
+L K L + L Q E+ K + EEN +L+R ++S + L+ ENK+L +
Sbjct: 674 KLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESE 733
Query: 184 QEKLK-------TELRKT-----------------SDALSKAQNDVMEMKMQSERLSKEY 219
+E+LK +KT L + + +++ + + L E
Sbjct: 734 KEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMEN 793
Query: 220 DQLLKEHSELQHSSFGEFLSKRSHKNGSIGKQTGS--------RKGSFRKRQQEKTVNFI 271
L K EL+ SS + L + +N S+ ++T K + R RQQ + I
Sbjct: 794 QTLQKNLEELKISS--KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE----I 847
Query: 272 KDT 274
KDT
Sbjct: 848 KDT 850
Score = 32.3 bits (72), Expect = 0.65
Identities = 19/78 (24%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
Query: 153 EENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQS 212
E E + +LK KD +E N L +++ LKT+L++ + Q ++ ++ Q+
Sbjct: 1032 ESQETTRELLKV--KDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQT 1089
Query: 213 ERLSKEYDQLLKEHSELQ 230
L ++ L ++++LQ
Sbjct: 1090 VSLQEQNTTLQTQNAKLQ 1107
Score = 32.0 bits (71), Expect = 0.84
Identities = 34/145 (23%), Positives = 61/145 (42%), Gaps = 19/145 (13%)
Query: 119 RLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENK 178
RL+ + A + K LKTQ + + L+R S +++ L+ +N
Sbjct: 1046 RLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSL-QEQNTTLQTQNA 1104
Query: 179 KLVEDQEKLKTE----LRKTSDAL---SKAQNDVMEMKMQSERLSKEYDQLLKEHSEL-- 229
KL + L ++ + + + L S +N+ + + E L YD L+K+H +L
Sbjct: 1105 KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLEL 1164
Query: 230 ----QHSSFGEFLSKR-----SHKN 245
Q S + +SK +HKN
Sbjct: 1165 LHERQASEYESLISKHGTLKSAHKN 1189
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 42.7 bits (99), Expect = 5e-04
Identities = 38/155 (24%), Positives = 70/155 (45%), Gaps = 17/155 (10%)
Query: 126 QLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQE 185
+L K N L+ Q EN NK ++ +EN+ LK+ + K V E + KL + E
Sbjct: 593 KLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLN-VYEIKVNKLELELE 651
Query: 186 KLKTELRKTSDALSKAQNDVMEMKMQSERLSKEY-------DQLLKEHSEL----QH--S 232
K + + +D Q ++ + K+ E L +E D+ +K E+ QH +
Sbjct: 652 SAKQKFGEITDTY---QKEIEDKKISEENLLEEVEKAKVIADEAVKLQKEIDKRCQHKIA 708
Query: 233 SFGEFLSKRSHKNGSIGKQTGSRKGSFRKRQQEKT 267
+ K H+ I ++ S G ++ ++QE++
Sbjct: 709 EMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQS 743
Score = 35.0 bits (79), Expect = 0.100
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 12/79 (15%)
Query: 154 ENEKLKRI-LKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQS 212
ENEKLK L SH L ENK+L ++ + EL+ Q D+ K Q
Sbjct: 507 ENEKLKNTELTSHCNK----LSLENKELTQETSDMTLELK-------NQQEDINNNKKQE 555
Query: 213 ERLSKEYDQLLKEHSELQH 231
ER+ K+ + L + ++L++
Sbjct: 556 ERMLKQIENLQETETQLRN 574
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 42.4 bits (98), Expect = 6e-04
Identities = 34/140 (24%), Positives = 61/140 (43%), Gaps = 13/140 (9%)
Query: 130 ELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKT 189
EL KG + Q + + + F EE EK + E VL E +KL E++ + +
Sbjct: 217 ELRRKGREEKQQQRRERQDRVFQEEEEK-------EWRKRETVLRKEEEKLQEEEPQRQR 269
Query: 190 ELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSEL---QHSSFGEFLSKRSHKNG 246
EL++ + L K + + + Q E ++ Q L+ +L Q E +R +
Sbjct: 270 ELQEEEEQLRKLERQELRRERQEE---EQQQQRLRREQQLRRKQEEERREQQEERREQQE 326
Query: 247 SIGKQTGSRKGSFRKRQQEK 266
+Q R+ R+ Q+E+
Sbjct: 327 RREQQEERREQQLRREQEER 346
Score = 36.2 bits (82), Expect = 0.045
Identities = 36/154 (23%), Positives = 69/154 (44%), Gaps = 18/154 (11%)
Query: 137 LKTQAENTNKAAKKFMEENEKLKRILKS--------HGKDEECVLEAENKKLVED--QEK 186
L+ + E + K EE E+L++ L+S + E+ + E K+L ++ +++
Sbjct: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566
Query: 187 LKTELRKTSDALSKAQNDVMEMKM---QSERLS-----KEYDQLLKEHSELQHSSFGEFL 238
LK E + D L K + + + ++ Q ERL +E ++L +E Q E
Sbjct: 567 LKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPE 626
Query: 239 SKRSHKNGSIGKQTGSRKGSFRKRQQEKTVNFIK 272
+R + +Q R+ R+ QQE+ +K
Sbjct: 627 EERRQQLLKSEEQEERRQQQLRREQQERREQRLK 660
Score = 34.7 bits (78), Expect = 0.13
Identities = 32/144 (22%), Positives = 64/144 (44%), Gaps = 21/144 (14%)
Query: 154 ENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSE 213
E E+L+R + K + + E + L E++E+ + R+ +D + + +++ + +
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRR--RQETDRKFREEEQLLQEREEQP 1352
Query: 214 RLSKEYDQLLKEHSELQHSSFG-EFLSKRSHKNGSIGKQTGSRKGSFRKRQQEKTVNFIK 272
+E D+ +E EL+H G +FL + R R+QE+ F+K
Sbjct: 1353 LRRQERDRKFREE-ELRHQEQGRKFLEEEQ-----------------RLRRQERERKFLK 1394
Query: 273 DTCNILCQNDNFVMLASRKFKFRK 296
+ + CQ + R KFR+
Sbjct: 1395 EEQQLRCQEREQQLRQDRDRKFRE 1418
Score = 30.8 bits (68), Expect = 1.9
Identities = 34/178 (19%), Positives = 78/178 (43%), Gaps = 30/178 (16%)
Query: 149 KKFMEENEKLKRILKSHGKDEECVL----------EAENKKLVEDQEKLKTEL--RKTSD 196
+KF+EE ++L++ ++EE +L + ++K +E++++L+ + RK +
Sbjct: 1446 RKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFRE 1505
Query: 197 ALSKAQNDVMEMKMQSERLSKEYDQ--LLKEHSELQHSSFG-------------EFLSKR 241
++Q + + ++L ++ Q L+E +L+ G E ++
Sbjct: 1506 QELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQ 1565
Query: 242 SHKNGSIGKQTGSRKGSFRK---RQQEKTVNFIKDTCNILCQNDNFVMLASRKFKFRK 296
+ + +Q RK + R+QE+ F++D + Q + R KFR+
Sbjct: 1566 EREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFRE 1623
Score = 30.4 bits (67), Expect = 2.5
Identities = 27/129 (20%), Positives = 58/129 (44%), Gaps = 5/129 (3%)
Query: 138 KTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDA 197
++Q + ++ + +EE K +R + L E + L E++E+L+ E R+
Sbjct: 864 RSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREERE---- 919
Query: 198 LSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSSFGEFLSKRSHKNGSIGKQTGSRKG 257
+ + + + E+L +E +QLL+E E + E ++ K +Q +
Sbjct: 920 -KRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEP 978
Query: 258 SFRKRQQEK 266
R+RQ+ +
Sbjct: 979 EKRRRQERE 987
Score = 30.4 bits (67), Expect = 2.5
Identities = 24/129 (18%), Positives = 57/129 (44%), Gaps = 16/129 (12%)
Query: 149 KKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQ----EKLKTELRKTSDALSKAQND 204
+KF+EE ++L+R E E K L E+Q ++ + +LR+ D + +
Sbjct: 1374 RKFLEEEQRLRR------------QERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQ 1421
Query: 205 VMEMKMQSERLSKEYDQLLKEHSELQHSSFGEFLSKRSHKNGSIGKQTGSRKGSFRKRQQ 264
+ + + + +E Q+ ++ E + + L + H+ +Q + + +Q
Sbjct: 1422 QLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQ 1481
Query: 265 EKTVNFIKD 273
E+ F+++
Sbjct: 1482 ERDRKFLEE 1490
Score = 30.0 bits (66), Expect = 3.2
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 13/112 (11%)
Query: 129 KELSNKGVLKTQAENTNKAAKKFMEENEKLKRIL----------KSHGKDEECVLEAENK 178
+E K L+ Q + +KFME+ ++L+R + +DE+ + E E +
Sbjct: 1575 QERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQ 1634
Query: 179 KLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQ 230
+L QE+ + L + + + Q +++ +R +E +QLL+E E Q
Sbjct: 1635 QL-HRQERDRKFLEE--EPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQ 1683
Score = 28.9 bits (63), Expect = 7.1
Identities = 25/128 (19%), Positives = 51/128 (39%), Gaps = 3/128 (2%)
Query: 142 ENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDALSKA 201
+ K K +E E+ +R LK ++ E ++L +QE+ + + K + +
Sbjct: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL 528
Query: 202 QNDVMEMKMQSERLSKEYDQLLKEHSEL---QHSSFGEFLSKRSHKNGSIGKQTGSRKGS 258
Q + + + +QLLK E Q ++ + + K+ R+
Sbjct: 529 QQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQ 588
Query: 259 FRKRQQEK 266
KR+QE+
Sbjct: 589 RLKREQEE 596
Score = 28.9 bits (63), Expect = 7.1
Identities = 22/128 (17%), Positives = 60/128 (46%), Gaps = 3/128 (2%)
Query: 140 QAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDALS 199
Q E + K+ E E+ +++LKS ++E + ++ +++LK E + + L
Sbjct: 612 QEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE--EEEERLE 669
Query: 200 KAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSSF-GEFLSKRSHKNGSIGKQTGSRKGS 258
+ E + + + L++E + +E + + + + S+ + + + ++G
Sbjct: 670 QRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQ 729
Query: 259 FRKRQQEK 266
R+++QE+
Sbjct: 730 RRRQEQEE 737
Score = 28.9 bits (63), Expect = 7.1
Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 14/77 (18%)
Query: 153 EENEKLKRI-LKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDALSKAQNDVMEMKMQ 211
EE EK +R L+ ++EE V + E + L E+ EK + + ++ +
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEPEK-------------RRRQELERQYRE 1172
Query: 212 SERLSKEYDQLLKEHSE 228
E L +E +QLL+E E
Sbjct: 1173 EEELQQEEEQLLREEQE 1189
Score = 28.5 bits (62), Expect = 9.3
Identities = 28/170 (16%), Positives = 75/170 (44%), Gaps = 9/170 (5%)
Query: 128 AKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKL 187
++E K + + Q + + +KF++E ++L+R + G+ + + ++E+L
Sbjct: 1510 SQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRR--QERGQQR----RQDRDRKFREEEQL 1563
Query: 188 KTELRKTSDALSKAQND-VMEMKMQSERLSKEYDQLLKEHSELQHSSFGEFLSKRSHKNG 246
+ E + LS+ + D ++ Q R ++ + +++ +L+ + L + +
Sbjct: 1564 RQE--REEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKF 1621
Query: 247 SIGKQTGSRKGSFRKRQQEKTVNFIKDTCNILCQNDNFVMLASRKFKFRK 296
+Q + + +QE+ F+++ + Q + R KFR+
Sbjct: 1622 REDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFRE 1671
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 42.4 bits (98), Expect = 6e-04
Identities = 34/141 (24%), Positives = 66/141 (46%), Gaps = 13/141 (9%)
Query: 116 VLRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
+L +V L LA+ + + E A +F +E ++ + + +E LE
Sbjct: 165 LLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKE-KLEK 223
Query: 176 ENKKLVEDQEKLKTELR-------KTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSE 228
E K++ D + +TE++ K+ + L K + + E K+ +ER +KE +Q +++
Sbjct: 224 ELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAK 283
Query: 229 L-----QHSSFGEFLSKRSHK 244
L QHS E LS+ + +
Sbjct: 284 LQQENEQHSLVCEQLSQENQQ 304
>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
Length = 1154
Score = 40.4 bits (93), Expect = 0.002
Identities = 29/130 (22%), Positives = 60/130 (46%), Gaps = 3/130 (2%)
Query: 138 KTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSDA 197
K+ N NK +K ME+ + L+ ++ G+ ++ +L+ E +L+E++++L+ +L+ +
Sbjct: 668 KSSKCNRNKQSKLLMEQMQALQ-VMYDAGQAKQELLQQEQGRLLEERKRLQADLQLCLEE 726
Query: 198 LSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSSFGEFLSKRSHKNGSIGKQTGSRKG 257
+ Q +KM E K Y ++ + + + S+ QT S+
Sbjct: 727 MQLLQVQSPSIKMSLESYGKSYGSMVPSNENCRKTYDTTVDDNESYYKSYTSTQTSSK-- 784
Query: 258 SFRKRQQEKT 267
SF K T
Sbjct: 785 SFLKSYDSST 794
Score = 29.6 bits (65), Expect = 4.2
Identities = 32/124 (25%), Positives = 55/124 (44%), Gaps = 24/124 (19%)
Query: 141 AENTNKAAKKFMEENEKLKRILKSHGK--DEECVLEAENKKLVEDQEKLKTELRK----- 193
A + + E EK K K G+ E+C L + +++ E+Q +L+ EL +
Sbjct: 533 ANKCDTLLSRLTELQEKYKASQKEMGQLQMEQCELLEDQRRMQEEQGQLQEELHRLTLPL 592
Query: 194 -TSDALSKAQ------NDVMEMKM-------QSERLSKEYDQLLKEHSELQHSSFGEFLS 239
S L K+Q D+ E+++ + ++L + D +LKE E+ H F
Sbjct: 593 PKSGLLLKSQELLTKLEDLCELQLLYQGMQEEQKKLIQNQDCVLKEQLEI-HEELRRF-- 649
Query: 240 KRSH 243
K SH
Sbjct: 650 KESH 653
>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
sapiens]
Length = 693
Score = 40.0 bits (92), Expect = 0.003
Identities = 35/149 (23%), Positives = 64/149 (42%), Gaps = 23/149 (15%)
Query: 134 KGVLKTQAENT------NKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKL 187
+G L++Q EN +K K+ ++E E++ R ++E E ++L E E+L
Sbjct: 315 EGKLQSQVENNQALSLLSKEQKQRLQEQEEMLR-------EQEAQRVREQERLCEQNERL 367
Query: 188 KTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHS-----SFGEFLSKRS 242
+ + + + + + ++ Q ERL KE ++L K+ L E L K+
Sbjct: 368 REQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQE 427
Query: 243 HK-----NGSIGKQTGSRKGSFRKRQQEK 266
+ N + KQ + SF EK
Sbjct: 428 ERLALSQNHKLDKQLAEPQCSFEDLNNEK 456
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 40.0 bits (92), Expect = 0.003
Identities = 35/149 (23%), Positives = 64/149 (42%), Gaps = 23/149 (15%)
Query: 134 KGVLKTQAENT------NKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKL 187
+G L++Q EN +K K+ ++E E++ R ++E E ++L E E+L
Sbjct: 315 EGKLQSQVENNQALSLLSKEQKQRLQEQEEMLR-------EQEAQRVREQERLCEQNERL 367
Query: 188 KTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHS-----SFGEFLSKRS 242
+ + + + + + ++ Q ERL KE ++L K+ L E L K+
Sbjct: 368 REQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQE 427
Query: 243 HK-----NGSIGKQTGSRKGSFRKRQQEK 266
+ N + KQ + SF EK
Sbjct: 428 ERLALSQNHKLDKQLAEPQCSFEDLNNEK 456
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 40.0 bits (92), Expect = 0.003
Identities = 22/106 (20%), Positives = 55/106 (51%), Gaps = 3/106 (2%)
Query: 116 VLRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
+L+ + + + + + +L+ Q E + A++ E+ E++ + L + + LEA
Sbjct: 2311 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2370
Query: 176 ENKKLVE---DQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKE 218
E ++ +E + E+LK + + S A ++A+ D + Q+E + ++
Sbjct: 2371 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2416
Score = 35.0 bits (79), Expect = 0.100
Identities = 31/128 (24%), Positives = 62/128 (48%), Gaps = 11/128 (8%)
Query: 137 LKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSD 196
LKT+AE A K+ ENE+L+R+ + + E + + +E+L +LRK SD
Sbjct: 1848 LKTEAEI---ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERL-AQLRKASD 1903
Query: 197 ALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSSFGEFLSKRSHKNGSIGKQTGSRK 256
+ + Q ++E ++ R +E LK +SF + + ++ +G+ + +
Sbjct: 1904 SELERQKGLVEDTLRQRRQVEEEILALK-------ASFEKAAAGKAELELELGRIRSNAE 1956
Query: 257 GSFRKRQQ 264
+ R ++Q
Sbjct: 1957 DTLRSKEQ 1964
Score = 31.2 bits (69), Expect = 1.4
Identities = 31/143 (21%), Positives = 68/143 (47%), Gaps = 17/143 (11%)
Query: 126 QLAKELSNKGVLKTQAENT----NKAAKKFMEENEKL-KRILKSHGKDEECVL------- 173
+L KE + + QAE +AA ME+++K ++ L+ + E+ +
Sbjct: 2137 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2196
Query: 174 EAENKKLVEDQE--KLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSEL-- 229
E +++K + D+E +LK E + + S+ + ++ +++Q E LSK ++ E+ L
Sbjct: 2197 ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALIL 2256
Query: 230 -QHSSFGEFLSKRSHKNGSIGKQ 251
+ FL + + K + ++
Sbjct: 2257 RDKDNTQRFLQEEAEKMKQVAEE 2279
Score = 29.6 bits (65), Expect = 4.2
Identities = 20/113 (17%), Positives = 59/113 (52%), Gaps = 5/113 (4%)
Query: 124 ITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL--- 180
+ +L ++ L+ +AE ++A++ E ++ L++ K ++ + ++L
Sbjct: 2011 VERLKAKVEEARRLRERAEQ--ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT 2068
Query: 181 VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSS 233
++ ++ + +LR ++A +A + E ++Q+ER + + + ++E L+ S+
Sbjct: 2069 LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSA 2121
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 40.0 bits (92), Expect = 0.003
Identities = 22/106 (20%), Positives = 55/106 (51%), Gaps = 3/106 (2%)
Query: 116 VLRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
+L+ + + + + + +L+ Q E + A++ E+ E++ + L + + LEA
Sbjct: 2315 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2374
Query: 176 ENKKLVE---DQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKE 218
E ++ +E + E+LK + + S A ++A+ D + Q+E + ++
Sbjct: 2375 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2420
Score = 35.0 bits (79), Expect = 0.100
Identities = 31/128 (24%), Positives = 62/128 (48%), Gaps = 11/128 (8%)
Query: 137 LKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSD 196
LKT+AE A K+ ENE+L+R+ + + E + + +E+L +LRK SD
Sbjct: 1852 LKTEAEI---ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERL-AQLRKASD 1907
Query: 197 ALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSSFGEFLSKRSHKNGSIGKQTGSRK 256
+ + Q ++E ++ R +E LK +SF + + ++ +G+ + +
Sbjct: 1908 SELERQKGLVEDTLRQRRQVEEEILALK-------ASFEKAAAGKAELELELGRIRSNAE 1960
Query: 257 GSFRKRQQ 264
+ R ++Q
Sbjct: 1961 DTLRSKEQ 1968
Score = 31.2 bits (69), Expect = 1.4
Identities = 31/143 (21%), Positives = 68/143 (47%), Gaps = 17/143 (11%)
Query: 126 QLAKELSNKGVLKTQAENT----NKAAKKFMEENEKL-KRILKSHGKDEECVL------- 173
+L KE + + QAE +AA ME+++K ++ L+ + E+ +
Sbjct: 2141 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2200
Query: 174 EAENKKLVEDQE--KLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSEL-- 229
E +++K + D+E +LK E + + S+ + ++ +++Q E LSK ++ E+ L
Sbjct: 2201 ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALIL 2260
Query: 230 -QHSSFGEFLSKRSHKNGSIGKQ 251
+ FL + + K + ++
Sbjct: 2261 RDKDNTQRFLQEEAEKMKQVAEE 2283
Score = 29.6 bits (65), Expect = 4.2
Identities = 20/113 (17%), Positives = 59/113 (52%), Gaps = 5/113 (4%)
Query: 124 ITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL--- 180
+ +L ++ L+ +AE ++A++ E ++ L++ K ++ + ++L
Sbjct: 2015 VERLKAKVEEARRLRERAEQ--ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT 2072
Query: 181 VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSS 233
++ ++ + +LR ++A +A + E ++Q+ER + + + ++E L+ S+
Sbjct: 2073 LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSA 2125
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 40.0 bits (92), Expect = 0.003
Identities = 22/106 (20%), Positives = 55/106 (51%), Gaps = 3/106 (2%)
Query: 116 VLRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
+L+ + + + + + +L+ Q E + A++ E+ E++ + L + + LEA
Sbjct: 2311 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2370
Query: 176 ENKKLVE---DQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKE 218
E ++ +E + E+LK + + S A ++A+ D + Q+E + ++
Sbjct: 2371 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2416
Score = 35.0 bits (79), Expect = 0.100
Identities = 31/128 (24%), Positives = 62/128 (48%), Gaps = 11/128 (8%)
Query: 137 LKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSD 196
LKT+AE A K+ ENE+L+R+ + + E + + +E+L +LRK SD
Sbjct: 1848 LKTEAEI---ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERL-AQLRKASD 1903
Query: 197 ALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSSFGEFLSKRSHKNGSIGKQTGSRK 256
+ + Q ++E ++ R +E LK +SF + + ++ +G+ + +
Sbjct: 1904 SELERQKGLVEDTLRQRRQVEEEILALK-------ASFEKAAAGKAELELELGRIRSNAE 1956
Query: 257 GSFRKRQQ 264
+ R ++Q
Sbjct: 1957 DTLRSKEQ 1964
Score = 31.2 bits (69), Expect = 1.4
Identities = 31/143 (21%), Positives = 68/143 (47%), Gaps = 17/143 (11%)
Query: 126 QLAKELSNKGVLKTQAENT----NKAAKKFMEENEKL-KRILKSHGKDEECVL------- 173
+L KE + + QAE +AA ME+++K ++ L+ + E+ +
Sbjct: 2137 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2196
Query: 174 EAENKKLVEDQE--KLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSEL-- 229
E +++K + D+E +LK E + + S+ + ++ +++Q E LSK ++ E+ L
Sbjct: 2197 ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALIL 2256
Query: 230 -QHSSFGEFLSKRSHKNGSIGKQ 251
+ FL + + K + ++
Sbjct: 2257 RDKDNTQRFLQEEAEKMKQVAEE 2279
Score = 29.6 bits (65), Expect = 4.2
Identities = 20/113 (17%), Positives = 59/113 (52%), Gaps = 5/113 (4%)
Query: 124 ITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL--- 180
+ +L ++ L+ +AE ++A++ E ++ L++ K ++ + ++L
Sbjct: 2011 VERLKAKVEEARRLRERAEQ--ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT 2068
Query: 181 VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSS 233
++ ++ + +LR ++A +A + E ++Q+ER + + + ++E L+ S+
Sbjct: 2069 LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSA 2121
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 40.0 bits (92), Expect = 0.003
Identities = 22/106 (20%), Positives = 55/106 (51%), Gaps = 3/106 (2%)
Query: 116 VLRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
+L+ + + + + + +L+ Q E + A++ E+ E++ + L + + LEA
Sbjct: 2279 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2338
Query: 176 ENKKLVE---DQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKE 218
E ++ +E + E+LK + + S A ++A+ D + Q+E + ++
Sbjct: 2339 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2384
Score = 35.0 bits (79), Expect = 0.100
Identities = 31/128 (24%), Positives = 62/128 (48%), Gaps = 11/128 (8%)
Query: 137 LKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSD 196
LKT+AE A K+ ENE+L+R+ + + E + + +E+L +LRK SD
Sbjct: 1816 LKTEAEI---ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERL-AQLRKASD 1871
Query: 197 ALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSSFGEFLSKRSHKNGSIGKQTGSRK 256
+ + Q ++E ++ R +E LK +SF + + ++ +G+ + +
Sbjct: 1872 SELERQKGLVEDTLRQRRQVEEEILALK-------ASFEKAAAGKAELELELGRIRSNAE 1924
Query: 257 GSFRKRQQ 264
+ R ++Q
Sbjct: 1925 DTLRSKEQ 1932
Score = 31.2 bits (69), Expect = 1.4
Identities = 31/143 (21%), Positives = 68/143 (47%), Gaps = 17/143 (11%)
Query: 126 QLAKELSNKGVLKTQAENT----NKAAKKFMEENEKL-KRILKSHGKDEECVL------- 173
+L KE + + QAE +AA ME+++K ++ L+ + E+ +
Sbjct: 2105 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2164
Query: 174 EAENKKLVEDQE--KLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSEL-- 229
E +++K + D+E +LK E + + S+ + ++ +++Q E LSK ++ E+ L
Sbjct: 2165 ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALIL 2224
Query: 230 -QHSSFGEFLSKRSHKNGSIGKQ 251
+ FL + + K + ++
Sbjct: 2225 RDKDNTQRFLQEEAEKMKQVAEE 2247
Score = 29.6 bits (65), Expect = 4.2
Identities = 20/113 (17%), Positives = 59/113 (52%), Gaps = 5/113 (4%)
Query: 124 ITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL--- 180
+ +L ++ L+ +AE ++A++ E ++ L++ K ++ + ++L
Sbjct: 1979 VERLKAKVEEARRLRERAEQ--ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT 2036
Query: 181 VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSS 233
++ ++ + +LR ++A +A + E ++Q+ER + + + ++E L+ S+
Sbjct: 2037 LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSA 2089
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 40.0 bits (92), Expect = 0.003
Identities = 22/106 (20%), Positives = 55/106 (51%), Gaps = 3/106 (2%)
Query: 116 VLRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
+L+ + + + + + +L+ Q E + A++ E+ E++ + L + + LEA
Sbjct: 2448 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2507
Query: 176 ENKKLVE---DQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKE 218
E ++ +E + E+LK + + S A ++A+ D + Q+E + ++
Sbjct: 2508 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2553
Score = 35.0 bits (79), Expect = 0.100
Identities = 31/128 (24%), Positives = 62/128 (48%), Gaps = 11/128 (8%)
Query: 137 LKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSD 196
LKT+AE A K+ ENE+L+R+ + + E + + +E+L +LRK SD
Sbjct: 1985 LKTEAEI---ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERL-AQLRKASD 2040
Query: 197 ALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSSFGEFLSKRSHKNGSIGKQTGSRK 256
+ + Q ++E ++ R +E LK +SF + + ++ +G+ + +
Sbjct: 2041 SELERQKGLVEDTLRQRRQVEEEILALK-------ASFEKAAAGKAELELELGRIRSNAE 2093
Query: 257 GSFRKRQQ 264
+ R ++Q
Sbjct: 2094 DTLRSKEQ 2101
Score = 31.2 bits (69), Expect = 1.4
Identities = 31/143 (21%), Positives = 68/143 (47%), Gaps = 17/143 (11%)
Query: 126 QLAKELSNKGVLKTQAENT----NKAAKKFMEENEKL-KRILKSHGKDEECVL------- 173
+L KE + + QAE +AA ME+++K ++ L+ + E+ +
Sbjct: 2274 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2333
Query: 174 EAENKKLVEDQE--KLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSEL-- 229
E +++K + D+E +LK E + + S+ + ++ +++Q E LSK ++ E+ L
Sbjct: 2334 ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALIL 2393
Query: 230 -QHSSFGEFLSKRSHKNGSIGKQ 251
+ FL + + K + ++
Sbjct: 2394 RDKDNTQRFLQEEAEKMKQVAEE 2416
Score = 29.6 bits (65), Expect = 4.2
Identities = 20/113 (17%), Positives = 59/113 (52%), Gaps = 5/113 (4%)
Query: 124 ITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL--- 180
+ +L ++ L+ +AE ++A++ E ++ L++ K ++ + ++L
Sbjct: 2148 VERLKAKVEEARRLRERAEQ--ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT 2205
Query: 181 VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSS 233
++ ++ + +LR ++A +A + E ++Q+ER + + + ++E L+ S+
Sbjct: 2206 LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSA 2258
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 40.0 bits (92), Expect = 0.003
Identities = 22/106 (20%), Positives = 55/106 (51%), Gaps = 3/106 (2%)
Query: 116 VLRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
+L+ + + + + + +L+ Q E + A++ E+ E++ + L + + LEA
Sbjct: 2289 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2348
Query: 176 ENKKLVE---DQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKE 218
E ++ +E + E+LK + + S A ++A+ D + Q+E + ++
Sbjct: 2349 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2394
Score = 35.0 bits (79), Expect = 0.100
Identities = 31/128 (24%), Positives = 62/128 (48%), Gaps = 11/128 (8%)
Query: 137 LKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSD 196
LKT+AE A K+ ENE+L+R+ + + E + + +E+L +LRK SD
Sbjct: 1826 LKTEAEI---ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERL-AQLRKASD 1881
Query: 197 ALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSSFGEFLSKRSHKNGSIGKQTGSRK 256
+ + Q ++E ++ R +E LK +SF + + ++ +G+ + +
Sbjct: 1882 SELERQKGLVEDTLRQRRQVEEEILALK-------ASFEKAAAGKAELELELGRIRSNAE 1934
Query: 257 GSFRKRQQ 264
+ R ++Q
Sbjct: 1935 DTLRSKEQ 1942
Score = 31.2 bits (69), Expect = 1.4
Identities = 31/143 (21%), Positives = 68/143 (47%), Gaps = 17/143 (11%)
Query: 126 QLAKELSNKGVLKTQAENT----NKAAKKFMEENEKL-KRILKSHGKDEECVL------- 173
+L KE + + QAE +AA ME+++K ++ L+ + E+ +
Sbjct: 2115 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2174
Query: 174 EAENKKLVEDQE--KLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSEL-- 229
E +++K + D+E +LK E + + S+ + ++ +++Q E LSK ++ E+ L
Sbjct: 2175 ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALIL 2234
Query: 230 -QHSSFGEFLSKRSHKNGSIGKQ 251
+ FL + + K + ++
Sbjct: 2235 RDKDNTQRFLQEEAEKMKQVAEE 2257
Score = 29.6 bits (65), Expect = 4.2
Identities = 20/113 (17%), Positives = 59/113 (52%), Gaps = 5/113 (4%)
Query: 124 ITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL--- 180
+ +L ++ L+ +AE ++A++ E ++ L++ K ++ + ++L
Sbjct: 1989 VERLKAKVEEARRLRERAEQ--ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT 2046
Query: 181 VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSS 233
++ ++ + +LR ++A +A + E ++Q+ER + + + ++E L+ S+
Sbjct: 2047 LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSA 2099
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 40.0 bits (92), Expect = 0.003
Identities = 22/106 (20%), Positives = 55/106 (51%), Gaps = 3/106 (2%)
Query: 116 VLRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
+L+ + + + + + +L+ Q E + A++ E+ E++ + L + + LEA
Sbjct: 2297 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2356
Query: 176 ENKKLVE---DQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKE 218
E ++ +E + E+LK + + S A ++A+ D + Q+E + ++
Sbjct: 2357 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2402
Score = 35.0 bits (79), Expect = 0.100
Identities = 31/128 (24%), Positives = 62/128 (48%), Gaps = 11/128 (8%)
Query: 137 LKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSD 196
LKT+AE A K+ ENE+L+R+ + + E + + +E+L +LRK SD
Sbjct: 1834 LKTEAEI---ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERL-AQLRKASD 1889
Query: 197 ALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSSFGEFLSKRSHKNGSIGKQTGSRK 256
+ + Q ++E ++ R +E LK +SF + + ++ +G+ + +
Sbjct: 1890 SELERQKGLVEDTLRQRRQVEEEILALK-------ASFEKAAAGKAELELELGRIRSNAE 1942
Query: 257 GSFRKRQQ 264
+ R ++Q
Sbjct: 1943 DTLRSKEQ 1950
Score = 31.2 bits (69), Expect = 1.4
Identities = 31/143 (21%), Positives = 68/143 (47%), Gaps = 17/143 (11%)
Query: 126 QLAKELSNKGVLKTQAENT----NKAAKKFMEENEKL-KRILKSHGKDEECVL------- 173
+L KE + + QAE +AA ME+++K ++ L+ + E+ +
Sbjct: 2123 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2182
Query: 174 EAENKKLVEDQE--KLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSEL-- 229
E +++K + D+E +LK E + + S+ + ++ +++Q E LSK ++ E+ L
Sbjct: 2183 ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALIL 2242
Query: 230 -QHSSFGEFLSKRSHKNGSIGKQ 251
+ FL + + K + ++
Sbjct: 2243 RDKDNTQRFLQEEAEKMKQVAEE 2265
Score = 29.6 bits (65), Expect = 4.2
Identities = 20/113 (17%), Positives = 59/113 (52%), Gaps = 5/113 (4%)
Query: 124 ITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL--- 180
+ +L ++ L+ +AE ++A++ E ++ L++ K ++ + ++L
Sbjct: 1997 VERLKAKVEEARRLRERAEQ--ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT 2054
Query: 181 VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSS 233
++ ++ + +LR ++A +A + E ++Q+ER + + + ++E L+ S+
Sbjct: 2055 LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSA 2107
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 40.0 bits (92), Expect = 0.003
Identities = 22/106 (20%), Positives = 55/106 (51%), Gaps = 3/106 (2%)
Query: 116 VLRRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEA 175
+L+ + + + + + +L+ Q E + A++ E+ E++ + L + + LEA
Sbjct: 2338 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2397
Query: 176 ENKKLVE---DQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKE 218
E ++ +E + E+LK + + S A ++A+ D + Q+E + ++
Sbjct: 2398 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2443
Score = 35.0 bits (79), Expect = 0.100
Identities = 31/128 (24%), Positives = 62/128 (48%), Gaps = 11/128 (8%)
Query: 137 LKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKLVEDQEKLKTELRKTSD 196
LKT+AE A K+ ENE+L+R+ + + E + + +E+L +LRK SD
Sbjct: 1875 LKTEAEI---ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERL-AQLRKASD 1930
Query: 197 ALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSSFGEFLSKRSHKNGSIGKQTGSRK 256
+ + Q ++E ++ R +E LK +SF + + ++ +G+ + +
Sbjct: 1931 SELERQKGLVEDTLRQRRQVEEEILALK-------ASFEKAAAGKAELELELGRIRSNAE 1983
Query: 257 GSFRKRQQ 264
+ R ++Q
Sbjct: 1984 DTLRSKEQ 1991
Score = 31.2 bits (69), Expect = 1.4
Identities = 31/143 (21%), Positives = 68/143 (47%), Gaps = 17/143 (11%)
Query: 126 QLAKELSNKGVLKTQAENT----NKAAKKFMEENEKL-KRILKSHGKDEECVL------- 173
+L KE + + QAE +AA ME+++K ++ L+ + E+ +
Sbjct: 2164 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2223
Query: 174 EAENKKLVEDQE--KLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSEL-- 229
E +++K + D+E +LK E + + S+ + ++ +++Q E LSK ++ E+ L
Sbjct: 2224 ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALIL 2283
Query: 230 -QHSSFGEFLSKRSHKNGSIGKQ 251
+ FL + + K + ++
Sbjct: 2284 RDKDNTQRFLQEEAEKMKQVAEE 2306
Score = 29.6 bits (65), Expect = 4.2
Identities = 20/113 (17%), Positives = 59/113 (52%), Gaps = 5/113 (4%)
Query: 124 ITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKRILKSHGKDEECVLEAENKKL--- 180
+ +L ++ L+ +AE ++A++ E ++ L++ K ++ + ++L
Sbjct: 2038 VERLKAKVEEARRLRERAEQ--ESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT 2095
Query: 181 VEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQHSS 233
++ ++ + +LR ++A +A + E ++Q+ER + + + ++E L+ S+
Sbjct: 2096 LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSA 2148
>gi|187761324 shootin1 isoform a [Homo sapiens]
Length = 631
Score = 40.0 bits (92), Expect = 0.003
Identities = 35/154 (22%), Positives = 69/154 (44%), Gaps = 12/154 (7%)
Query: 118 RRLVTLITQLAKELSNKGVLKTQAENTNKAAKKFMEENEKLKR---ILKSHGKDEECVLE 174
+++ L Q+ K +L + EN + +EE K+K+ +L S ++ VLE
Sbjct: 142 KQIKELRDQIVSVQEEKKILAIELENLKSKLVEVIEEVNKVKQEKTVLNSEVLEQRKVLE 201
Query: 175 AENKK---LVEDQEKLKTELRKTSDALSKAQNDVMEMKMQSERLSKEYDQLLKEHSELQH 231
N+ VE+ E+++ L D KA++ EM ++ +L ++ H LQ
Sbjct: 202 KCNRVSMLAVEEYEEMQVNLELEKDLRKKAESFAQEMFIEQNKLKRQ------SHLLLQS 255
Query: 232 SSFGEFLSKRSHKNGSIGKQTGSRKGSFRKRQQE 265
S + L K +N + +Q + +++ +E
Sbjct: 256 SIPDQQLLKALDENAKLTQQLEEERIQHQQKVKE 289
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.135 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,051,967
Number of Sequences: 37866
Number of extensions: 425868
Number of successful extensions: 4767
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 142
Number of HSP's successfully gapped in prelim test: 485
Number of HSP's that attempted gapping in prelim test: 3565
Number of HSP's gapped (non-prelim): 1615
length of query: 348
length of database: 18,247,518
effective HSP length: 103
effective length of query: 245
effective length of database: 14,347,320
effective search space: 3515093400
effective search space used: 3515093400
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.