Search of human proteins with 134288884

Search of human proteins with 134288884

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|134288884 glutamyl-tRNA synthetase 2 [Homo sapiens]
         (523 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|134288884 glutamyl-tRNA synthetase 2 [Homo sapiens]               1045   0.0  
gi|62241042 glutamyl-prolyl tRNA synthetase [Homo sapiens]             65   2e-10
gi|4826960 glutaminyl-tRNA synthetase [Homo sapiens]                   56   7e-08
gi|53729363 leucine rich repeat and sterile alpha motif containi...    33   0.83 
gi|53729361 leucine rich repeat and sterile alpha motif containi...    33   0.83 
gi|53729359 leucine rich repeat and sterile alpha motif containi...    33   0.83 
gi|124028525 phenylalanyl-tRNA synthetase, beta subunit [Homo sa...    32   1.4  
gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo s...    32   1.4  
gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sa...    32   1.4  
gi|239787094 A20-binding inhibitor of NF-kappaB activation 2 iso...    31   2.4  
gi|239787092 A20-binding inhibitor of NF-kappaB activation 2 iso...    31   2.4  
gi|239745085 PREDICTED: similar to Golgin subfamily A member 8-l...    31   2.4  
gi|113418608 PREDICTED: hypothetical protein LOC441239 [Homo sap...    30   7.0  
gi|169170482 PREDICTED: hypothetical protein LOC441239 [Homo sap...    30   7.0  
gi|157674354 WD repeat domain 72 [Homo sapiens]                        30   7.0  
gi|169171788 PREDICTED: hypothetical protein LOC441239 [Homo sap...    29   9.2  
gi|169172306 PREDICTED: hypothetical protein LOC441239 [Homo sap...    29   9.2  

>gi|134288884 glutamyl-tRNA synthetase 2 [Homo sapiens]
          Length = 523

 Score = 1045 bits (2702), Expect = 0.0
 Identities = 523/523 (100%), Positives = 523/523 (100%)

Query: 1   MAALLRRLLQRERPSAASGRPVGRREANLGTDAGVAVRVRFAPSPTGFLHLGGLRTALYN 60
           MAALLRRLLQRERPSAASGRPVGRREANLGTDAGVAVRVRFAPSPTGFLHLGGLRTALYN
Sbjct: 1   MAALLRRLLQRERPSAASGRPVGRREANLGTDAGVAVRVRFAPSPTGFLHLGGLRTALYN 60

Query: 61  YIFAKKYQGSFILRLEDTDQTRVVPGAAENIEDMLEWAGIPPDESPRRGGPAGPYQQSQR 120
           YIFAKKYQGSFILRLEDTDQTRVVPGAAENIEDMLEWAGIPPDESPRRGGPAGPYQQSQR
Sbjct: 61  YIFAKKYQGSFILRLEDTDQTRVVPGAAENIEDMLEWAGIPPDESPRRGGPAGPYQQSQR 120

Query: 121 LELYAQATEALLKTGAAYPCFCSPQRLELLKKEALRNHQTPRYDNRCRNMSQEQVAQKLA 180
           LELYAQATEALLKTGAAYPCFCSPQRLELLKKEALRNHQTPRYDNRCRNMSQEQVAQKLA
Sbjct: 121 LELYAQATEALLKTGAAYPCFCSPQRLELLKKEALRNHQTPRYDNRCRNMSQEQVAQKLA 180

Query: 181 KDPKPAIRFRLEQVVPAFQDLVYGWNRHEVASVEGDPVIMKSDGFPTYHLACVVDDHHMG 240
           KDPKPAIRFRLEQVVPAFQDLVYGWNRHEVASVEGDPVIMKSDGFPTYHLACVVDDHHMG
Sbjct: 181 KDPKPAIRFRLEQVVPAFQDLVYGWNRHEVASVEGDPVIMKSDGFPTYHLACVVDDHHMG 240

Query: 241 ISHVLRGSEWLVSTAKHLLLYQALGWQPPHFAHLPLLLNRDGSKLSKRQGDVFLEHFAAD 300
           ISHVLRGSEWLVSTAKHLLLYQALGWQPPHFAHLPLLLNRDGSKLSKRQGDVFLEHFAAD
Sbjct: 241 ISHVLRGSEWLVSTAKHLLLYQALGWQPPHFAHLPLLLNRDGSKLSKRQGDVFLEHFAAD 300

Query: 301 GFLPDSLLDIITNCGSGFAENQMGRTLPELITQFNLTQVTCHSALLDLEKLPEFNRLHLQ 360
           GFLPDSLLDIITNCGSGFAENQMGRTLPELITQFNLTQVTCHSALLDLEKLPEFNRLHLQ
Sbjct: 301 GFLPDSLLDIITNCGSGFAENQMGRTLPELITQFNLTQVTCHSALLDLEKLPEFNRLHLQ 360

Query: 361 RLVSNESQRRQLVGKLQVLVEEAFGCQLQNRDVLNPVYVERILLLRQGHICRLQDLVSPV 420
           RLVSNESQRRQLVGKLQVLVEEAFGCQLQNRDVLNPVYVERILLLRQGHICRLQDLVSPV
Sbjct: 361 RLVSNESQRRQLVGKLQVLVEEAFGCQLQNRDVLNPVYVERILLLRQGHICRLQDLVSPV 420

Query: 421 YSYLWTRPAVGRAQLDAISEKVDVIAKRVLGLLERSSMSLTQDMLNGELKKLSEGLEGTK 480
           YSYLWTRPAVGRAQLDAISEKVDVIAKRVLGLLERSSMSLTQDMLNGELKKLSEGLEGTK
Sbjct: 421 YSYLWTRPAVGRAQLDAISEKVDVIAKRVLGLLERSSMSLTQDMLNGELKKLSEGLEGTK 480

Query: 481 YSNVMKLLRMALSGQQQGPPVAEMMLALGPKEVRERIQKVVSS 523
           YSNVMKLLRMALSGQQQGPPVAEMMLALGPKEVRERIQKVVSS
Sbjct: 481 YSNVMKLLRMALSGQQQGPPVAEMMLALGPKEVRERIQKVVSS 523


>gi|62241042 glutamyl-prolyl tRNA synthetase [Homo sapiens]
          Length = 1512

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 71/298 (23%), Positives = 127/298 (42%), Gaps = 26/298 (8%)

Query: 11  RERPSAASGRPVGRREANLGTDAGVAVRVRFAPSPTGFLHLGGLRTALYNYIFAKKYQGS 70
           + R +    + VG+     G + G  V VRF P  +G+LH+G  + AL N  +   ++G 
Sbjct: 173 KARVAPEKKQDVGKFVELPGAEMG-KVTVRFPPEASGYLHIGHAKAALLNQHYQVNFKGK 231

Query: 71  FILRLEDTDQTRVVPGAAENIEDMLEWAGIPPDESPRRGGPAGPYQQSQRLELYAQATEA 130
            I+R +DT+  +      + I + +    I PD+             S   E   +  E 
Sbjct: 232 LIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFT---------YTSDHFETIMKYAEK 282

Query: 131 LLKTGAAYPCFCSPQRLELLKKEALRNHQTPRYDNRCRNMSQEQVAQKLAKDPKPAIRFR 190
           L++ G AY        ++    E ++  +  R D++ R    E+  Q + ++ K   +F 
Sbjct: 283 LIQEGKAY--------VDDTPAEQMKAEREQRIDSKHRKNPIEKNLQ-MWEEMKKGSQFG 333

Query: 191 LEQVVPAFQDLV--YGWNRHEV---ASVEGDP-VIMKSDGFPTYHLACVVDDHHMGISHV 244
               + A  D+    G  R        ++  P    K + +PTY  AC + D   G++H 
Sbjct: 334 QSCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHA 393

Query: 245 LRGSEWLVSTAKHLLLYQALGWQPPHFAHLPLLLNRDGSKLSKRQGDVFLEHFAADGF 302
           LR +E+     +   + +ALG + P+       LN + + LSKR+   F+     DG+
Sbjct: 394 LRTTEYHDRDEQFYWIIEALGIRKPYIWEYS-RLNLNNTVLSKRKLTWFVNEGLVDGW 450


>gi|4826960 glutaminyl-tRNA synthetase [Homo sapiens]
          Length = 775

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 41/118 (34%), Positives = 54/118 (45%), Gaps = 12/118 (10%)

Query: 34  GVAVRVRFAPSPTGFLHLGGLRTALYNYIFAKKYQGSFILRLEDTDQTRVVPGAAENIED 93
           G  VR RF P P G LH+G  +   +N+ +AK   G   LR +DT+  +        I D
Sbjct: 261 GGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICD 320

Query: 94  MLEWAGIPPDESPRRGGPAGPYQQSQRLELYAQATEALLKTGAAYPCFCSPQRLELLK 151
           M+ W G  P +          Y      +LYA A E L++ G AY C    QR E LK
Sbjct: 321 MVAWLGYTPYKV--------TYASDYFDQLYAWAVE-LIRRGLAYVCH---QRGEELK 366


>gi|53729363 leucine rich repeat and sterile alpha motif containing
           1 [Homo sapiens]
          Length = 723

 Score = 32.7 bits (73), Expect = 0.83
 Identities = 44/186 (23%), Positives = 76/186 (40%), Gaps = 13/186 (6%)

Query: 336 LTQVTCHSALLDLEKLPEFNRLHLQRLVSNESQRRQLVGKLQVLVEEAFGCQLQNRDVLN 395
           LTQ+      LD E L        Q ++S   QR  L   LQ L++E    + + R++L 
Sbjct: 485 LTQLELKRKSLDTESL--------QEMISE--QRWALSSLLQQLLKEKQQREEELREILT 534

Query: 396 PVYVERILLLRQGHICRLQDLVSPVYSYLWTRPAVGRAQLDAISEKVDVIAKRVLGLLER 455
            +  +         + + Q L++     L  +      QL A+ E++       +    R
Sbjct: 535 ELEAKSETRQENYWLIQYQRLLNQKPLSLKLQEEGMERQLVALLEELSAEHYLPIFAHHR 594

Query: 456 SSMSLTQDMLNGELKKLS---EGLEGTKYSNVMKLLRMALSGQQQGPPVAEMMLALGPKE 512
            S+ L   M  G+L K+     GL+      V +LL  A    +  PP+ E++    P+E
Sbjct: 595 LSLDLLSQMSPGDLAKVGVSEAGLQHEILRRVQELLDAARIQPELKPPMGEVVTPTAPQE 654

Query: 513 VRERIQ 518
             E ++
Sbjct: 655 PPESVR 660


>gi|53729361 leucine rich repeat and sterile alpha motif containing
           1 [Homo sapiens]
          Length = 723

 Score = 32.7 bits (73), Expect = 0.83
 Identities = 44/186 (23%), Positives = 76/186 (40%), Gaps = 13/186 (6%)

Query: 336 LTQVTCHSALLDLEKLPEFNRLHLQRLVSNESQRRQLVGKLQVLVEEAFGCQLQNRDVLN 395
           LTQ+      LD E L        Q ++S   QR  L   LQ L++E    + + R++L 
Sbjct: 485 LTQLELKRKSLDTESL--------QEMISE--QRWALSSLLQQLLKEKQQREEELREILT 534

Query: 396 PVYVERILLLRQGHICRLQDLVSPVYSYLWTRPAVGRAQLDAISEKVDVIAKRVLGLLER 455
            +  +         + + Q L++     L  +      QL A+ E++       +    R
Sbjct: 535 ELEAKSETRQENYWLIQYQRLLNQKPLSLKLQEEGMERQLVALLEELSAEHYLPIFAHHR 594

Query: 456 SSMSLTQDMLNGELKKLS---EGLEGTKYSNVMKLLRMALSGQQQGPPVAEMMLALGPKE 512
            S+ L   M  G+L K+     GL+      V +LL  A    +  PP+ E++    P+E
Sbjct: 595 LSLDLLSQMSPGDLAKVGVSEAGLQHEILRRVQELLDAARIQPELKPPMGEVVTPTAPQE 654

Query: 513 VRERIQ 518
             E ++
Sbjct: 655 PPESVR 660


>gi|53729359 leucine rich repeat and sterile alpha motif containing
           1 [Homo sapiens]
          Length = 723

 Score = 32.7 bits (73), Expect = 0.83
 Identities = 44/186 (23%), Positives = 76/186 (40%), Gaps = 13/186 (6%)

Query: 336 LTQVTCHSALLDLEKLPEFNRLHLQRLVSNESQRRQLVGKLQVLVEEAFGCQLQNRDVLN 395
           LTQ+      LD E L        Q ++S   QR  L   LQ L++E    + + R++L 
Sbjct: 485 LTQLELKRKSLDTESL--------QEMISE--QRWALSSLLQQLLKEKQQREEELREILT 534

Query: 396 PVYVERILLLRQGHICRLQDLVSPVYSYLWTRPAVGRAQLDAISEKVDVIAKRVLGLLER 455
            +  +         + + Q L++     L  +      QL A+ E++       +    R
Sbjct: 535 ELEAKSETRQENYWLIQYQRLLNQKPLSLKLQEEGMERQLVALLEELSAEHYLPIFAHHR 594

Query: 456 SSMSLTQDMLNGELKKLS---EGLEGTKYSNVMKLLRMALSGQQQGPPVAEMMLALGPKE 512
            S+ L   M  G+L K+     GL+      V +LL  A    +  PP+ E++    P+E
Sbjct: 595 LSLDLLSQMSPGDLAKVGVSEAGLQHEILRRVQELLDAARIQPELKPPMGEVVTPTAPQE 654

Query: 513 VRERIQ 518
             E ++
Sbjct: 655 PPESVR 660


>gi|124028525 phenylalanyl-tRNA synthetase, beta subunit [Homo
           sapiens]
          Length = 589

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 24/114 (21%), Positives = 50/114 (43%), Gaps = 17/114 (14%)

Query: 274 LPLLLNRDGSKLSKRQGDVFLEHFAADGFLPDSLLDIITNCGSGFAENQM---------- 323
           +P ++N D S+++    ++F+E    D      +LDII    S + ENQ           
Sbjct: 233 MPPIINGDHSRITVNTRNIFIECTGTDFTKAKIVLDIIVTMFSEYCENQFTVEAAEVVFP 292

Query: 324 ---GRTLPELITQFNLTQVTCHSALLDLEKLPEFNRLHLQRLVSNESQRRQLVG 374
                T PEL  +  + +    +  + + + PE    +L +L++    + +++G
Sbjct: 293 NGKSHTFPELAYRKEMVRADLINKKVGIRETPE----NLAKLLTRMYLKSEVIG 342


>gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo
           sapiens]
          Length = 468

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 32/109 (29%), Positives = 44/109 (40%), Gaps = 4/109 (3%)

Query: 83  VVPGAAENIEDMLEWAGIPPDESPRRGGPAGPYQQSQRLELYAQATEALLKTGAAYPCFC 142
           + P     +E  LEW G      P    P+   + S  L LY +A E LL  G       
Sbjct: 99  LTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLY-EAPEELLADGEGGGTDE 157

Query: 143 SPQRLELLKKEALRNHQTPRYDNRCRNMSQEQVAQKLAKDPKPAIRFRL 191
               + LL  EA  + + P       +  Q+ +AQ LA+ P P  R RL
Sbjct: 158 GIYDVPLLGPEAPPSPEPP---GALASHDQDTLAQLLARSPPPPHRPRL 203


>gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo
           sapiens]
          Length = 561

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 32/109 (29%), Positives = 44/109 (40%), Gaps = 4/109 (3%)

Query: 83  VVPGAAENIEDMLEWAGIPPDESPRRGGPAGPYQQSQRLELYAQATEALLKTGAAYPCFC 142
           + P     +E  LEW G      P    P+   + S  L LY +A E LL  G       
Sbjct: 192 LTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRASALLNLY-EAPEELLADGEGGGTDE 250

Query: 143 SPQRLELLKKEALRNHQTPRYDNRCRNMSQEQVAQKLAKDPKPAIRFRL 191
               + LL  EA  + + P       +  Q+ +AQ LA+ P P  R RL
Sbjct: 251 GIYDVPLLGPEAPPSPEPP---GALASHDQDTLAQLLARSPPPPHRPRL 296


>gi|239787094 A20-binding inhibitor of NF-kappaB activation 2
           isoform 2 [Homo sapiens]
          Length = 322

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 1/58 (1%)

Query: 144 PQRLELLKKEALR-NHQTPRYDNRCRNMSQEQVAQKLAKDPKPAIRFRLEQVVPAFQD 200
           P   EL++KE  R N Q     N C  + QE  A + A+D        LEQ + A++D
Sbjct: 144 PHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAYKD 201


>gi|239787092 A20-binding inhibitor of NF-kappaB activation 2
           isoform 1 [Homo sapiens]
          Length = 429

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 1/58 (1%)

Query: 144 PQRLELLKKEALR-NHQTPRYDNRCRNMSQEQVAQKLAKDPKPAIRFRLEQVVPAFQD 200
           P   EL++KE  R N Q     N C  + QE  A + A+D        LEQ + A++D
Sbjct: 251 PHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAYKD 308


>gi|239745085 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 isoform 3 [Homo sapiens]
          Length = 601

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 34/130 (26%), Positives = 55/130 (42%), Gaps = 15/130 (11%)

Query: 102 PDESPRRGGPAGPYQQSQRLELYAQATEALLKTGAAYPCFCSPQRLELL---KKEALRNH 158
           P E P     A      + LE  A A +A ++           QR+ LL   +KE LR  
Sbjct: 300 PPEPPAVPSEAELQHLRKELERVAGALQAQVEYN---------QRISLLNEGQKERLREQ 350

Query: 159 QT--PRYDNRCRNMSQEQVAQKLAKDPKPAIRFRLEQVVPAFQDLVYGWNRHEVASVEGD 216
           Q   P  + R + +++ Q + K   +   ++  +LEQ V   Q+ +     H VAS + +
Sbjct: 351 QERLPEQEERLQQLAEPQNSFKELNNENKSV-LQLEQQVKELQEKLGKRLAHLVASAQKE 409

Query: 217 PVIMKSDGFP 226
           P   +  G P
Sbjct: 410 PEAARGPGAP 419


>gi|113418608 PREDICTED: hypothetical protein LOC441239 [Homo
           sapiens]
          Length = 301

 Score = 29.6 bits (65), Expect = 7.0
 Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 2/41 (4%)

Query: 73  LRLEDTDQTRVVPGAAENIEDMLEWAGIPP--DESPRRGGP 111
           LR E+T + RV PGAA N  D+ E   +    D +P +G P
Sbjct: 59  LRSEETVEDRVAPGAARNQGDLEETGNLASRGDAAPGKGLP 99


>gi|169170482 PREDICTED: hypothetical protein LOC441239 [Homo
           sapiens]
          Length = 542

 Score = 29.6 bits (65), Expect = 7.0
 Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 2/41 (4%)

Query: 73  LRLEDTDQTRVVPGAAENIEDMLEWAGIPP--DESPRRGGP 111
           LR E+T + RV PGAA N  D+ E   +    D +P +G P
Sbjct: 59  LRSEETVEDRVAPGAARNQGDLEETGNLASRGDAAPGKGLP 99


>gi|157674354 WD repeat domain 72 [Homo sapiens]
          Length = 1102

 Score = 29.6 bits (65), Expect = 7.0
 Identities = 13/39 (33%), Positives = 19/39 (48%), Gaps = 1/39 (2%)

Query: 230 LACVVDDHHMGISHVLRGSEWLVSTAKHLLLYQALGWQP 268
           + CV  DH + + H L G   L+   KHL   + + W P
Sbjct: 530 ICCVCGDHSVALLH-LEGKSCLLHARKHLFPVRMIKWHP 567


>gi|169171788 PREDICTED: hypothetical protein LOC441239 [Homo
           sapiens]
          Length = 301

 Score = 29.3 bits (64), Expect = 9.2
 Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 2/41 (4%)

Query: 73  LRLEDTDQTRVVPGAAENIEDMLEWAGIPP--DESPRRGGP 111
           LR E+T + RV PGAA N  D+ E   +    D +P +G P
Sbjct: 59  LRSEETVEDRVAPGAARNQGDLEESGNLASRGDAAPGKGLP 99


>gi|169172306 PREDICTED: hypothetical protein LOC441239 [Homo
           sapiens]
          Length = 505

 Score = 29.3 bits (64), Expect = 9.2
 Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 2/41 (4%)

Query: 73  LRLEDTDQTRVVPGAAENIEDMLEWAGIPP--DESPRRGGP 111
           LR E+T + RV PGAA N  D+ E   +    D +P +G P
Sbjct: 59  LRSEETVEDRVAPGAARNQGDLEESGNLASRGDAAPGKGLP 99


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,430,858
Number of Sequences: 37866
Number of extensions: 942103
Number of successful extensions: 2166
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 2158
Number of HSP's gapped (non-prelim): 21
length of query: 523
length of database: 18,247,518
effective HSP length: 107
effective length of query: 416
effective length of database: 14,195,856
effective search space: 5905476096
effective search space used: 5905476096
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.