Guide to the Human Genome
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Search of human proteins with 55743071

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|55743071 ATPase, Cu++ transporting, beta polypeptide isoform
a [Homo sapiens]
         (1465 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|55743071 ATPase, Cu++ transporting, beta polypeptide isoform ...  2862   0.0  
gi|115529486 ATPase, Cu++ transporting, alpha polypeptide [Homo ...  1539   0.0  
gi|55743073 ATPase, Cu++ transporting, beta polypeptide isoform ...  1360   0.0  
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap...    93   2e-18
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap...    93   2e-18
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap...    93   2e-18
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap...    93   2e-18
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom...    87   2e-16
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...    87   2e-16
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom...    87   2e-16
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...    87   2e-16
gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom...    87   2e-16
gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom...    87   2e-16
gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom...    87   2e-16
gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H...    85   4e-16
gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [...    85   4e-16
gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ...    85   4e-16
gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [...    85   4e-16
gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [...    85   4e-16
gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ...    84   1e-15
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]    80   1e-14
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa...    78   5e-14
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa...    78   5e-14
gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens]                 78   7e-14
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi...    77   9e-14
gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]     76   2e-13
gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]    76   3e-13
gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]              75   4e-13
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa...    75   5e-13
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa...    75   5e-13

>gi|55743071 ATPase, Cu++ transporting, beta polypeptide isoform a
            [Homo sapiens]
          Length = 1465

 Score = 2862 bits (7420), Expect = 0.0
 Identities = 1465/1465 (100%), Positives = 1465/1465 (100%)

Query: 1    MPEQERQITAREGASRKILSKLSLPTRAWEPAMKKSFAFDNVGYEGGLDGLGPSSQVATS 60
            MPEQERQITAREGASRKILSKLSLPTRAWEPAMKKSFAFDNVGYEGGLDGLGPSSQVATS
Sbjct: 1    MPEQERQITAREGASRKILSKLSLPTRAWEPAMKKSFAFDNVGYEGGLDGLGPSSQVATS 60

Query: 61   TVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMG 120
            TVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMG
Sbjct: 61   TVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMG 120

Query: 121  FEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSN 180
            FEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSN
Sbjct: 121  FEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSN 180

Query: 181  QEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSAN 240
            QEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSAN
Sbjct: 181  QEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSAN 240

Query: 241  QNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVK 300
            QNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVK
Sbjct: 241  QNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVK 300

Query: 301  YDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGSPPRNQVQGTCST 360
            YDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGSPPRNQVQGTCST
Sbjct: 301  YDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGSPPRNQVQGTCST 360

Query: 361  TLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDM 420
            TLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDM
Sbjct: 361  TLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDM 420

Query: 421  GFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHTGRLPANHAPDILAKSPQ 480
            GFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHTGRLPANHAPDILAKSPQ
Sbjct: 421  GFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHTGRLPANHAPDILAKSPQ 480

Query: 481  STRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPL 540
            STRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPL
Sbjct: 481  STRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPL 540

Query: 541  EIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALA 600
            EIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALA
Sbjct: 541  EIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALA 600

Query: 601  TSKALVKFDPEIIGPRDIIKIIEEIGFHASLAQRNPNAHHLDHKMEIKQWKKSFLCSLVF 660
            TSKALVKFDPEIIGPRDIIKIIEEIGFHASLAQRNPNAHHLDHKMEIKQWKKSFLCSLVF
Sbjct: 601  TSKALVKFDPEIIGPRDIIKIIEEIGFHASLAQRNPNAHHLDHKMEIKQWKKSFLCSLVF 660

Query: 661  GIPVMALMIYMLIPSNEPHQSMVLDHNIIPGLSILNLIFFILCTFVQLLGGWYFYVQAYK 720
            GIPVMALMIYMLIPSNEPHQSMVLDHNIIPGLSILNLIFFILCTFVQLLGGWYFYVQAYK
Sbjct: 661  GIPVMALMIYMLIPSNEPHQSMVLDHNIIPGLSILNLIFFILCTFVQLLGGWYFYVQAYK 720

Query: 721  SLRHRSANMDVLIVLATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWL 780
            SLRHRSANMDVLIVLATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWL
Sbjct: 721  SLRHRSANMDVLIVLATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWL 780

Query: 781  EHLAKSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFP 840
            EHLAKSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFP
Sbjct: 781  EHLAKSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFP 840

Query: 841  VDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLIKATHVGNDTTLAQIV 900
            VDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLIKATHVGNDTTLAQIV
Sbjct: 841  VDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLIKATHVGNDTTLAQIV 900

Query: 901  KLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNKH 960
            KLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNKH
Sbjct: 901  KLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNKH 960

Query: 961  ISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHK 1020
            ISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHK
Sbjct: 961  ISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHK 1020

Query: 1021 IKTVMFDKTGTITHGVPRVMRVLLLGDVATLPLRKVLAVVGTAEASSEHPLGVAVTKYCK 1080
            IKTVMFDKTGTITHGVPRVMRVLLLGDVATLPLRKVLAVVGTAEASSEHPLGVAVTKYCK
Sbjct: 1021 IKTVMFDKTGTITHGVPRVMRVLLLGDVATLPLRKVLAVVGTAEASSEHPLGVAVTKYCK 1080

Query: 1081 EELGTETLGYCTDFQAVPGCGIGCKVSNVEGILAHSERPLSAPASHLNEAGSLPAEKDAV 1140
            EELGTETLGYCTDFQAVPGCGIGCKVSNVEGILAHSERPLSAPASHLNEAGSLPAEKDAV
Sbjct: 1081 EELGTETLGYCTDFQAVPGCGIGCKVSNVEGILAHSERPLSAPASHLNEAGSLPAEKDAV 1140

Query: 1141 PQTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQ 1200
            PQTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQ
Sbjct: 1141 PQTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQ 1200

Query: 1201 EAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNKGK 1260
            EAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNKGK
Sbjct: 1201 EAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNKGK 1260

Query: 1261 KVAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRR 1320
            KVAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRR
Sbjct: 1261 KVAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRR 1320

Query: 1321 IRINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMGSAAMAASSVSVVLSSLQLKCYKKPD 1380
            IRINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMGSAAMAASSVSVVLSSLQLKCYKKPD
Sbjct: 1321 IRINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMGSAAMAASSVSVVLSSLQLKCYKKPD 1380

Query: 1381 LERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYVSQVSLSSLTSDKPSR 1440
            LERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYVSQVSLSSLTSDKPSR
Sbjct: 1381 LERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYVSQVSLSSLTSDKPSR 1440

Query: 1441 HSAAADDDGDKWSLLLNGRDEEQYI 1465
            HSAAADDDGDKWSLLLNGRDEEQYI
Sbjct: 1441 HSAAADDDGDKWSLLLNGRDEEQYI 1465


>gi|115529486 ATPase, Cu++ transporting, alpha polypeptide [Homo
            sapiens]
          Length = 1500

 Score = 1539 bits (3984), Expect = 0.0
 Identities = 826/1461 (56%), Positives = 1045/1461 (71%), Gaps = 66/1461 (4%)

Query: 38   AFDNVGYEGGLDGLGPSSQVATSTVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGS 97
            A D++G++  +    P   +  +    +  +       I+  +   KG+  +K+  ++ +
Sbjct: 65   AIDDMGFDAVIHNPDPLPVLTDTLFLTVTASLTLPWDHIQSTLLKTKGVTDIKIYPQKRT 124

Query: 98   ATVKYVPSVVCLQQVCHQIGDMGFEASIAEGKAASWPSRSLP-AQEAVVKLRVEGMTCQS 156
              V  +PS+V   Q+   + ++  +    E K+ +    S+  A E V+K++VEGMTC S
Sbjct: 125  VAVTIIPSIVNANQIKELVPELSLDTGTLEKKSGACEDHSMAQAGEVVLKMKVEGMTCHS 184

Query: 157  CVSSIEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAP 216
            C S+IEGK+ KLQGV R+KVSL NQEA I YQP+LI  E+++  +  MGF A +K +   
Sbjct: 185  CTSTIEGKIGKLQGVQRIKVSLDNQEATIVYQPHLISVEEMKKQIEAMGFPAFVKKQPKY 244

Query: 217  LSLGPIDIERLQSTNPKRPLSSANQNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIE 276
            L LG ID+ERL++T    P+ S+  +   S +  +      T    IDGMHCKSCV NIE
Sbjct: 245  LKLGAIDVERLKNT----PVKSSEGSQQRSPSYTNDS----TATFIIDGMHCKSCVSNIE 296

Query: 277  ENIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGT 336
              +  L  V SI VSLEN++A VKY+ S  +P +L++AIEA+ PG ++VS+    E +  
Sbjct: 297  STLSALQYVSSIVVSLENRSAIVKYNASSVTPESLRKAIEAVSPGLYRVSITSEVESTSN 356

Query: 337  DHRSSSSHSPGSPPRNQV-QGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLA 395
               S SS S    P N V Q     T+I I GMTC SCV SIEG+IS+  GV+ I VSLA
Sbjct: 357  ---SPSSSSLQKIPLNVVSQPLTQETVINIDGMTCNSCVQSIEGVISKKPGVKSIRVSLA 413

Query: 396  EGTATVLYNPSVISPEELRAAIEDMGFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTS 455
                TV Y+P + SPE LR AIEDMGF+A++   S +  PL                P+S
Sbjct: 414  NSNGTVEYDPLLTSPETLRGAIEDMGFDATL---SDTNEPL-----------VVIAQPSS 459

Query: 456  VQEVAPHTGRLPANHAPDILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAG 515
               +   T          +  K      +    KC++Q+ GMTCASCV+NIERNL++E G
Sbjct: 460  EMPLLTSTNEFYTKGMTPVQDKEEGKNSS----KCYIQVTGMTCASCVANIERNLRREEG 515

Query: 516  VLSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTC 575
            + S+LVALMAGKAE++Y+P VIQP  IA+FI++LGF A V+E+    DG +EL + GMTC
Sbjct: 516  IYSILVALMAGKAEVRYNPAVIQPPMIAEFIRELGFGATVIENADEGDGVLELVVRGMTC 575

Query: 576  ASCVHNIESKLTRTNGITYASVALATSKALVKFDPEIIGPRDIIKIIEEIGFHASLAQRN 635
            ASCVH IES LT+  GI Y SVALAT+KA +K+DPEIIGPRDII  IE +GF ASL +++
Sbjct: 576  ASCVHKIESSLTKHRGILYCSVALATNKAHIKYDPEIIGPRDIIHTIESLGFEASLVKKD 635

Query: 636  PNAHHLDHKMEIKQWKKSFLCSLVFGIPVMALMIYMLIPSNE-----------------P 678
             +A HLDHK EI+QW++SFL SL F IPVM LMIYM++  +                   
Sbjct: 636  RSASHLDHKREIRQWRRSFLVSLFFCIPVMGLMIYMMVMDHHFATLHHNQNMSKEEMINL 695

Query: 679  HQSMVLDHNIIPGLSILNLIFFILCTFVQLLGGWYFYVQAYKSLRHRSANMDVLIVLATS 738
            H SM L+  I+PGLS++NL+ F+LC  VQ  GGWYFY+QAYK+L+H++ANMDVLIVLAT+
Sbjct: 696  HSSMFLERQILPGLSVMNLLSFLLCVPVQFFGGWYFYIQAYKALKHKTANMDVLIVLATT 755

Query: 739  IAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWLEHLAKSKTSEALAKLMSL 798
            IA+ YSL+IL+VA+ E+A+ +P+TFFDTPPMLFVFIALGRWLEH+AK KTSEALAKL+SL
Sbjct: 756  IAFAYSLIILLVAMYERAKVNPITFFDTPPMLFVFIALGRWLEHIAKGKTSEALAKLISL 815

Query: 799  QATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTMADESLIT 858
            QATEAT+VTL  DN+++ EEQV +ELVQRGDI+KVVPGGKFPVDG+V+EG++M DESLIT
Sbjct: 816  QATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLIT 875

Query: 859  GEAMPVTKKPGSTVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLAD 918
            GEAMPV KKPGSTVIAGSIN +GS+LI ATHVG DTTL+QIVKLVEEAQ SKAPIQQ AD
Sbjct: 876  GEAMPVAKKPGSTVIAGSINQNGSLLICATHVGADTTLSQIVKLVEEAQTSKAPIQQFAD 935

Query: 919  RFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNKHISQTEVIIRFAFQTSITV 978
            + SGYFVPFI+ +S  TL+VWIVIGF++F +V+ YFP  N+ IS+TE IIRFAFQ SITV
Sbjct: 936  KLSGYFVPFIVFVSIATLLVWIVIGFLNFEIVETYFPGYNRSISRTETIIRFAFQASITV 995

Query: 979  LCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPR 1038
            LCIACPCSLGLATPTAVMVGTGV AQNGILIKGG+PLEMAHK+K V+FDKTGTITHG P 
Sbjct: 996  LCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPV 1055

Query: 1039 VMRVLLLGDVATLPLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYCTDFQAVP 1098
            V +V +L +   +   K+LA+VGTAE++SEHPLG A+TKYCK+EL TETLG C DFQ VP
Sbjct: 1056 VNQVKVLTESNRISHHKILAIVGTAESNSEHPLGTAITKYCKQELDTETLGTCIDFQVVP 1115

Query: 1099 GCGIGCKVSNVEGILAHSERPLS-----------APASHLNEAGSLPAEKDAV------P 1141
            GCGI CKV+N+EG+L  +   +              AS+   + S     DA        
Sbjct: 1116 GCGISCKVTNIEGLLHKNNWNIEDNNIKNASLVQIDASNEQSSTSSSMIIDAQISNALNA 1175

Query: 1142 QTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQE 1201
            Q + VLIGNREW+ RNGL I++DV+D MT+HE KG+TA+LVA+D  LCG+IAIAD VK E
Sbjct: 1176 QQYKVLIGNREWMIRNGLVINNDVNDFMTEHERKGRTAVLVAVDDELCGLIAIADTVKPE 1235

Query: 1202 AALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNKGKK 1261
            A LA+H L+SMG++VVL+TGDN KTAR+IA+QVGI KVFAEVLPSHKVAKV++LQ +GK+
Sbjct: 1236 AELAIHILKSMGLEVVLMTGDNSKTARSIASQVGITKVFAEVLPSHKVAKVKQLQEEGKR 1295

Query: 1262 VAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRI 1321
            VAMVGDG+NDSPALA A++G+AIGTGTDVAIEAADVVLIRNDLLDVVASI LS+ TV+RI
Sbjct: 1296 VAMVGDGINDSPALAMANVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRI 1355

Query: 1322 RINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMGSAAMAASSVSVVLSSLQLKCYKKPDL 1381
            RIN V ALIYNLVGIPIAAGVFMPIG+VLQPWMGSAAMAASSVSVVLSSL LK Y+KP  
Sbjct: 1356 RINFVFALIYNLVGIPIAAGVFMPIGLVLQPWMGSAAMAASSVSVVLSSLFLKLYRKPTY 1415

Query: 1382 ERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYVSQVSLSSLTSDKPSRH 1441
            E YE  A   +   + S++SVH+G+DD  R+SP+    D++   S+ S++SL SDK S +
Sbjct: 1416 ESYELPARSQIGQKSPSEISVHVGIDDTSRNSPKLGLLDRIVNYSRASINSLLSDKRSLN 1475

Query: 1442 SAAADDDGDKWSLLLNGRDEE 1462
            S    +  DK SLL+    E+
Sbjct: 1476 SVVTSEP-DKHSLLVGDFRED 1495



 Score =  228 bits (582), Expect = 3e-59
 Identities = 187/643 (29%), Positives = 281/643 (43%), Gaps = 121/643 (18%)

Query: 51  LGPSSQVATSTVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQ 110
           + PS  V + T+ + GMTC SCV +IE +I  + G+  +KVSLE+ +AT+ Y P +   +
Sbjct: 1   MDPSMGVNSVTISVEGMTCNSCVWTIEQQIGKVNGVHHIKVSLEEKNATIIYDPKLQTPK 60

Query: 111 QVCHQIGDMGFEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQG 170
            +   I DMGF+A I            LP     + L V           I+  + K +G
Sbjct: 61  TLQEAIDDMGFDAVIHN-------PDPLPVLTDTLFLTVTASLTLPW-DHIQSTLLKTKG 112

Query: 171 VVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLGPIDIERLQST 230
           V  +K+    +   +T  P ++                 IK  V  LSL    +E+    
Sbjct: 113 VTDIKIYPQKRTVAVTIIPSIVNANQ-------------IKELVPELSLDTGTLEKKSGA 159

Query: 231 NPKRPLSSANQNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSIQV 290
                ++ A +               V L+++++GM C SC   IE  IG+L GVQ I+V
Sbjct: 160 CEDHSMAQAGE---------------VVLKMKVEGMTCHSCTSTIEGKIGKLQGVQRIKV 204

Query: 291 SLENKTAQVKYDPSCTSPVALQRAIEAL--------PPGNFKVSLPDGAEGSGTDHRSSS 342
           SL+N+ A + Y P   S   +++ IEA+         P   K+   D      T  +SS 
Sbjct: 205 SLDNQEATIVYQPHLISVEEMKKQIEAMGFPAFVKKQPKYLKLGAIDVERLKNTPVKSSE 264

Query: 343 SHSPGSPPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVL 402
               GS  R+      ST    I GM C SCV +IE  +S L+ V  I VSL   +A V 
Sbjct: 265 ----GSQQRSPSYTNDSTATFIIDGMHCKSCVSNIESTLSALQYVSSIVVSLENRSAIVK 320

Query: 403 YNPSVISPEELRAAIEDMG---FEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEV 459
           YN S ++PE LR AIE +    +  S+ SE                V++T  +P+S    
Sbjct: 321 YNASSVTPESLRKAIEAVSPGLYRVSITSE----------------VESTSNSPSS---- 360

Query: 460 APHTGRLPANHAPDILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSV 519
                ++P N     L            Q+  + I GMTC SCV +IE  + K+ GV S+
Sbjct: 361 -SSLQKIPLNVVSQPLT-----------QETVINIDGMTCNSCVQSIEGVISKKPGVKSI 408

Query: 520 LVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAVME---------------------- 557
            V+L      ++YDP +  P  +   I+D+GF+A + +                      
Sbjct: 409 RVSLANSNGTVEYDPLLTSPETLRGAIEDMGFDATLSDTNEPLVVIAQPSSEMPLLTSTN 468

Query: 558 -------------DYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALATSKA 604
                        +   +     + +TGMTCASCV NIE  L R  GI    VAL   KA
Sbjct: 469 EFYTKGMTPVQDKEEGKNSSKCYIQVTGMTCASCVANIERNLRREEGIYSILVALMAGKA 528

Query: 605 LVKFDPEIIGPRDIIKIIEEIGFHASLAQRNPNAHHLDHKMEI 647
            V+++P +I P  I + I E+GF A++ +   NA   D  +E+
Sbjct: 529 EVRYNPAVIQPPMIAEFIRELGFGATVIE---NADEGDGVLEL 568


>gi|55743073 ATPase, Cu++ transporting, beta polypeptide isoform b
            [Homo sapiens]
          Length = 1258

 Score = 1360 bits (3521), Expect = 0.0
 Identities = 811/1360 (59%), Positives = 916/1360 (67%), Gaps = 190/1360 (13%)

Query: 140  AQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRD 199
            +Q A   +R+ GMTCQSCV SIE ++  L+G++ +KVSL    A + Y P ++  + +  
Sbjct: 55   SQVATSTVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCH 114

Query: 200  HVNDMGFEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSANQNFNNSETLGHQGSHVVTL 259
             + DMGFEA+I    A             ++ P R L +                    +
Sbjct: 115  QIGDMGFEASIAEGKA-------------ASWPSRSLPAQE----------------AVV 145

Query: 260  QLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVKYDPSCTSP----------- 308
            +LR++GM C+SCV +IE  + +L GV  ++VSL N+ A + Y P    P           
Sbjct: 146  KLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMG 205

Query: 309  --VALQRAIEALPPGNFKVSLPDGAEG----SGTDHRSSSSHSPGSPPRNQVQGTCSTTL 362
               A++  +  L  G   +            S  +   ++S + G       QG+   TL
Sbjct: 206  FEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSANQNFNNSETLGH------QGSHVVTL 259

Query: 363  -IAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDMG 421
             + I GM C SCV +IE  I QL GVQ I VSL   TA V Y+PS  SP  L+ AIE + 
Sbjct: 260  QLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEAL- 318

Query: 422  FEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHTGRLPANHAPDILAKSPQS 481
                         P GN     S+    +G+ T  +  + H+   P    P    +   S
Sbjct: 319  -------------PPGNFKV--SLPDGAEGSGTDHRSSSSHSPGSP----PRNQVQGTCS 359

Query: 482  TRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPLE 541
            T  +A       I GMTCASCV +IE  + +  GV  + V+L  G A + Y+P VI P E
Sbjct: 360  TTLIA-------IAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEE 412

Query: 542  IAQFIQDLGFEAAVMEDYAGSD--GNIELTITGMTCASCVHNIESKLTRTNGITYASV-- 597
            +   I+D+GFEA+V+ +   ++  GN              H+  + + +T   T  SV  
Sbjct: 413  LRAAIEDMGFEASVVSESCSTNPLGN--------------HSAGNSMVQTTDGTPTSVQE 458

Query: 598  -ALATSKALVKFDPEIIG--PRDIIKIIEEIGFHASLAQRNPNAHHLDHKMEIKQWK-KS 653
             A  T +      P+I+   P+    +  +  F                 ++IK     S
Sbjct: 459  VAPHTGRLPANHAPDILAKSPQSTRAVAPQKCF-----------------LQIKGMTCAS 501

Query: 654  FLCSLVFGIPVMALMIYMLIPSNEPHQSMVLDHNIIPGLSILNLIFFILCTFVQLLGGWY 713
             + ++   +   A ++ +L+        +  D  +I  L I          F+Q LG   
Sbjct: 502  CVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPLEIAQ--------FIQDLG--- 550

Query: 714  FYVQAYKSLRHRSANMDVLIVLATSIAYVYSLV--------ILVVAVAEKAERSPVTFFD 765
            F     +       N+++ I   T  + V+++         I   +VA    ++ V F  
Sbjct: 551  FEAAVMEDYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDP 610

Query: 766  TPPMLFVFIALGRWLEHLAKSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELV 825
                    I   R +  + +SKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELV
Sbjct: 611  E-------IIGPRDIIKIIESKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELV 663

Query: 826  QRGDIVKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLI 885
            QRGDIVKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLI
Sbjct: 664  QRGDIVKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLI 723

Query: 886  KATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIVIGFI 945
            KATHVGNDTTLAQIVKLVEEAQMSK                                   
Sbjct: 724  KATHVGNDTTLAQIVKLVEEAQMSK----------------------------------- 748

Query: 946  DFGVVQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQN 1005
                      NPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQN
Sbjct: 749  ----------NPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQN 798

Query: 1006 GILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGDVATLPLRKVLAVVGTAEA 1065
            GILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGDVATLPLRKVLAVVGTAEA
Sbjct: 799  GILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGDVATLPLRKVLAVVGTAEA 858

Query: 1066 SSEHPLGVAVTKYCKEELGTETLGYCTDFQAVPGCGIGCKVSNVEGILAHSERPLSAPAS 1125
            SSEHPLGVAVTKYCKEELGTETLGYCTDFQAVPGCGIGCKVSNVEGILAHSERPLSAPAS
Sbjct: 859  SSEHPLGVAVTKYCKEELGTETLGYCTDFQAVPGCGIGCKVSNVEGILAHSERPLSAPAS 918

Query: 1126 HLNEAGSLPAEKDAVPQTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAID 1185
            HLNEAGSLPAEKDAVPQTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAID
Sbjct: 919  HLNEAGSLPAEKDAVPQTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAID 978

Query: 1186 GVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLP 1245
            GVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLP
Sbjct: 979  GVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLP 1038

Query: 1246 SHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLL 1305
            SHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLL
Sbjct: 1039 SHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLL 1098

Query: 1306 DVVASIHLSKRTVRRIRINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMGSAAMAASSVS 1365
            DVVASIHLSKRTVRRIRINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMGSAAMAASSVS
Sbjct: 1099 DVVASIHLSKRTVRRIRINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMGSAAMAASSVS 1158

Query: 1366 VVLSSLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYV 1425
            VVLSSLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYV
Sbjct: 1159 VVLSSLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYV 1218

Query: 1426 SQVSLSSLTSDKPSRHSAAADDDGDKWSLLLNGRDEEQYI 1465
            SQVSLSSLTSDKPSRHSAAADDDGDKWSLLLNGRDEEQYI
Sbjct: 1219 SQVSLSSLTSDKPSRHSAAADDDGDKWSLLLNGRDEEQYI 1258



 Score = 1221 bits (3160), Expect = 0.0
 Identities = 623/623 (100%), Positives = 623/623 (100%)

Query: 1   MPEQERQITAREGASRKILSKLSLPTRAWEPAMKKSFAFDNVGYEGGLDGLGPSSQVATS 60
           MPEQERQITAREGASRKILSKLSLPTRAWEPAMKKSFAFDNVGYEGGLDGLGPSSQVATS
Sbjct: 1   MPEQERQITAREGASRKILSKLSLPTRAWEPAMKKSFAFDNVGYEGGLDGLGPSSQVATS 60

Query: 61  TVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMG 120
           TVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMG
Sbjct: 61  TVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMG 120

Query: 121 FEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSN 180
           FEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSN
Sbjct: 121 FEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSN 180

Query: 181 QEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSAN 240
           QEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSAN
Sbjct: 181 QEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSAN 240

Query: 241 QNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVK 300
           QNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVK
Sbjct: 241 QNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVK 300

Query: 301 YDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGSPPRNQVQGTCST 360
           YDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGSPPRNQVQGTCST
Sbjct: 301 YDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGSPPRNQVQGTCST 360

Query: 361 TLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDM 420
           TLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDM
Sbjct: 361 TLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDM 420

Query: 421 GFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHTGRLPANHAPDILAKSPQ 480
           GFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHTGRLPANHAPDILAKSPQ
Sbjct: 421 GFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHTGRLPANHAPDILAKSPQ 480

Query: 481 STRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPL 540
           STRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPL
Sbjct: 481 STRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPL 540

Query: 541 EIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALA 600
           EIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALA
Sbjct: 541 EIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALA 600

Query: 601 TSKALVKFDPEIIGPRDIIKIIE 623
           TSKALVKFDPEIIGPRDIIKIIE
Sbjct: 601 TSKALVKFDPEIIGPRDIIKIIE 623



 Score =  194 bits (494), Expect = 4e-49
 Identities = 142/451 (31%), Positives = 214/451 (47%), Gaps = 78/451 (17%)

Query: 232 PKRPLSSANQNFNNSETLGHQG--------SHVVTLQLRIDGMHCKSCVLNIEENIGQLL 283
           P R    A +     + +G++G        S V T  +RI GM C+SCV +IE+ I  L 
Sbjct: 25  PTRAWEPAMKKSFAFDNVGYEGGLDGLGPSSQVATSTVRILGMTCQSCVKSIEDRISNLK 84

Query: 284 GVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSS 343
           G+ S++VSLE  +A VKY PS    V LQ+    +    F+ S+ +G   S         
Sbjct: 85  GIISMKVSLEQGSATVKYVPSV---VCLQQVCHQIGDMGFEASIAEGKAASW-------- 133

Query: 344 HSPGSPPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLY 403
                 P   +    +   + + GMTC SCV SIEG + +L+GV ++ VSL+   A + Y
Sbjct: 134 ------PSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQEAVITY 187

Query: 404 NPSVISPEELRAAIEDMGFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHT 463
            P +I PE+LR  + DMGFEA++ S+    + LG               P  ++ +    
Sbjct: 188 QPYLIQPEDLRDHVNDMGFEAAIKSKVAPLS-LG---------------PIDIERLQSTN 231

Query: 464 GRLPANHAPDILAKSP----QSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSV 519
            + P + A      S     Q +  V  Q   L+I GM C SCV NIE N+ +  GV S+
Sbjct: 232 PKRPLSSANQNFNNSETLGHQGSHVVTLQ---LRIDGMHCKSCVLNIEENIGQLLGVQSI 288

Query: 520 LVALMAGKAEIKYDPEVIQPLEIAQFIQDL---GFEAAVMEDYAGS-------------- 562
            V+L    A++KYDP    P+ + + I+ L    F+ ++ +   GS              
Sbjct: 289 QVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGS 348

Query: 563 ------DGNIELT---ITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDPEII 613
                  G    T   I GMTCASCVH+IE  +++  G+   SV+LA   A V ++P +I
Sbjct: 349 PPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVI 408

Query: 614 GPRDIIKIIEEIGFHASLAQR----NPNAHH 640
            P ++   IE++GF AS+       NP  +H
Sbjct: 409 SPEELRAAIEDMGFEASVVSESCSTNPLGNH 439



 Score =  185 bits (470), Expect = 2e-46
 Identities = 137/436 (31%), Positives = 205/436 (47%), Gaps = 74/436 (16%)

Query: 25  PTRAWEPAMKKSFAFDNVGYEGGLDGLGPSSQVATSTVRILGMTCQSCVKSIEDRISNLK 84
           P R    A +     + +G++G        S V T  +RI GM C+SCV +IE+ I  L 
Sbjct: 232 PKRPLSSANQNFNNSETLGHQG--------SHVVTLQLRIDGMHCKSCVLNIEENIGQLL 283

Query: 85  GIISMKVSLEQGSATVKYVPSV---VCLQQVCHQIGDMGFEASIAEGKAASW-------- 133
           G+ S++VSLE  +A VKY PS    V LQ+    +    F+ S+ +G   S         
Sbjct: 284 GVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSS 343

Query: 134 ------PSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQEAVITY 187
                 P   +    +   + + GMTC SCV SIEG + +L+GV ++ VSL+   A + Y
Sbjct: 344 HSPGSPPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLY 403

Query: 188 QPYLIQPEDLRDHVNDMGFEAAIKSKVAPLS-LG---------------PIDIERLQSTN 231
            P +I PE+LR  + DMGFEA++ S+    + LG               P  ++ +    
Sbjct: 404 NPSVISPEELRAAIEDMGFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHT 463

Query: 232 PKRPLSSANQNFNNSETLGHQGSHVVTLQ---LRIDGMHCKSCVLNIEENIGQLLGVQSI 288
            + P + A      S     Q +  V  Q   L+I GM C SCV NIE N+ +  GV S+
Sbjct: 464 GRLPANHAPDILAKSP----QSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSV 519

Query: 289 QVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGS 348
            V+L    A++KYDP    P+ + + I+ L    F+ ++ +   GS              
Sbjct: 520 LVALMAGKAEIKYDPEVIQPLEIAQFIQDL---GFEAAVMEDYAGS-------------- 562

Query: 349 PPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVI 408
                  G    T   I GMTCASCVH+IE  +++  G+   SV+LA   A V ++P +I
Sbjct: 563 ------DGNIELT---ITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDPEII 613

Query: 409 SPEELRAAIEDMGFEA 424
            P ++   IE    EA
Sbjct: 614 GPRDIIKIIESKTSEA 629



 Score = 98.2 bits (243), Expect = 5e-20
 Identities = 51/150 (34%), Positives = 83/150 (55%), Gaps = 9/150 (6%)

Query: 62  VRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMGF 121
           ++I GMTC SCV +IE  +    G++S+ V+L  G A +KY P V+   ++   I D+GF
Sbjct: 492 LQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGF 551

Query: 122 EASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQ 181
           EA++ E  A S         +  ++L + GMTC SCV +IE K+ +  G+    V+L+  
Sbjct: 552 EAAVMEDYAGS---------DGNIELTITGMTCASCVHNIESKLTRTNGITYASVALATS 602

Query: 182 EAVITYQPYLIQPEDLRDHVNDMGFEAAIK 211
           +A++ + P +I P D+   +     EA  K
Sbjct: 603 KALVKFDPEIIGPRDIIKIIESKTSEALAK 632


>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sapiens]
          Length = 939

 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 58/161 (36%), Positives = 86/161 (53%), Gaps = 28/161 (17%)

Query: 1190 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINK----------- 1238
            G++ I D  +     AV TL + GV + +ITGD+++TA AIA+++G+             
Sbjct: 540  GLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEI 599

Query: 1239 ----------------VFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGV 1282
                            VF    P HK+  ++ LQ  G  VAM GDGVND+ AL  AD+GV
Sbjct: 600  DAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGV 659

Query: 1283 AIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIR 1322
            A+G TGTDV  EAAD++L+ +D   ++++I   K     I+
Sbjct: 660  AMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIK 700



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 60/287 (20%), Positives = 111/287 (38%), Gaps = 47/287 (16%)

Query: 764  FDTPPMLFVFIALGRWLEHLAKSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPME 823
            FD    + V I +   +  + + ++ ++L +L  L   E   V  G+    +  + VP  
Sbjct: 100  FDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVP-- 157

Query: 824  LVQRGDIVKVVPGGKFPVDGKVLEGNTMA-DESLITGEAMPVTK--KPGSTVIAGSINAH 880
                GD V +  G + P D ++ E   ++ DES +TGE  P +K   P      G + + 
Sbjct: 158  ----GDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASR 213

Query: 881  GSVLIKATHV------------GNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGY--FVP 926
             ++    T V            G ++   ++ K+++  +  K P+Q+  D       F  
Sbjct: 214  SNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYS 273

Query: 927  FIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCS 986
            F II   + LV W++                 K I +        F  S+++   A P  
Sbjct: 274  FGII-GIIMLVGWLL----------------GKDILEM-------FTISVSLAVAAIPEG 309

Query: 987  LGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTIT 1033
            L +     + +G     +   ++K    +E       +  DKTGT+T
Sbjct: 310  LPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLT 356


>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sapiens]
          Length = 949

 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 58/161 (36%), Positives = 86/161 (53%), Gaps = 28/161 (17%)

Query: 1190 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINK----------- 1238
            G++ I D  +     AV TL + GV + +ITGD+++TA AIA+++G+             
Sbjct: 540  GLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEI 599

Query: 1239 ----------------VFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGV 1282
                            VF    P HK+  ++ LQ  G  VAM GDGVND+ AL  AD+GV
Sbjct: 600  DAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGV 659

Query: 1283 AIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIR 1322
            A+G TGTDV  EAAD++L+ +D   ++++I   K     I+
Sbjct: 660  AMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIK 700



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 60/287 (20%), Positives = 111/287 (38%), Gaps = 47/287 (16%)

Query: 764  FDTPPMLFVFIALGRWLEHLAKSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPME 823
            FD    + V I +   +  + + ++ ++L +L  L   E   V  G+    +  + VP  
Sbjct: 100  FDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVP-- 157

Query: 824  LVQRGDIVKVVPGGKFPVDGKVLEGNTMA-DESLITGEAMPVTK--KPGSTVIAGSINAH 880
                GD V +  G + P D ++ E   ++ DES +TGE  P +K   P      G + + 
Sbjct: 158  ----GDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASR 213

Query: 881  GSVLIKATHV------------GNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGY--FVP 926
             ++    T V            G ++   ++ K+++  +  K P+Q+  D       F  
Sbjct: 214  SNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYS 273

Query: 927  FIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCS 986
            F II   + LV W++                 K I +        F  S+++   A P  
Sbjct: 274  FGII-GIIMLVGWLL----------------GKDILEM-------FTISVSLAVAAIPEG 309

Query: 987  LGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTIT 1033
            L +     + +G     +   ++K    +E       +  DKTGT+T
Sbjct: 310  LPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLT 356


>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sapiens]
          Length = 888

 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 58/161 (36%), Positives = 86/161 (53%), Gaps = 28/161 (17%)

Query: 1190 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINK----------- 1238
            G++ I D  +     AV TL + GV + +ITGD+++TA AIA+++G+             
Sbjct: 540  GLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEI 599

Query: 1239 ----------------VFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGV 1282
                            VF    P HK+  ++ LQ  G  VAM GDGVND+ AL  AD+GV
Sbjct: 600  DAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGV 659

Query: 1283 AIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIR 1322
            A+G TGTDV  EAAD++L+ +D   ++++I   K     I+
Sbjct: 660  AMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIK 700



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 60/287 (20%), Positives = 111/287 (38%), Gaps = 47/287 (16%)

Query: 764  FDTPPMLFVFIALGRWLEHLAKSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPME 823
            FD    + V I +   +  + + ++ ++L +L  L   E   V  G+    +  + VP  
Sbjct: 100  FDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVP-- 157

Query: 824  LVQRGDIVKVVPGGKFPVDGKVLEGNTMA-DESLITGEAMPVTK--KPGSTVIAGSINAH 880
                GD V +  G + P D ++ E   ++ DES +TGE  P +K   P      G + + 
Sbjct: 158  ----GDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASR 213

Query: 881  GSVLIKATHV------------GNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGY--FVP 926
             ++    T V            G ++   ++ K+++  +  K P+Q+  D       F  
Sbjct: 214  SNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYS 273

Query: 927  FIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCS 986
            F II   + LV W++                 K I +        F  S+++   A P  
Sbjct: 274  FGII-GIIMLVGWLL----------------GKDILEM-------FTISVSLAVAAIPEG 309

Query: 987  LGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTIT 1033
            L +     + +G     +   ++K    +E       +  DKTGT+T
Sbjct: 310  LPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLT 356


>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sapiens]
          Length = 919

 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 58/161 (36%), Positives = 86/161 (53%), Gaps = 28/161 (17%)

Query: 1190 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINK----------- 1238
            G++ I D  +     AV TL + GV + +ITGD+++TA AIA+++G+             
Sbjct: 540  GLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEI 599

Query: 1239 ----------------VFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGV 1282
                            VF    P HK+  ++ LQ  G  VAM GDGVND+ AL  AD+GV
Sbjct: 600  DAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGV 659

Query: 1283 AIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIR 1322
            A+G TGTDV  EAAD++L+ +D   ++++I   K     I+
Sbjct: 660  AMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIK 700



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 60/287 (20%), Positives = 111/287 (38%), Gaps = 47/287 (16%)

Query: 764  FDTPPMLFVFIALGRWLEHLAKSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPME 823
            FD    + V I +   +  + + ++ ++L +L  L   E   V  G+    +  + VP  
Sbjct: 100  FDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVP-- 157

Query: 824  LVQRGDIVKVVPGGKFPVDGKVLEGNTMA-DESLITGEAMPVTK--KPGSTVIAGSINAH 880
                GD V +  G + P D ++ E   ++ DES +TGE  P +K   P      G + + 
Sbjct: 158  ----GDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASR 213

Query: 881  GSVLIKATHV------------GNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGY--FVP 926
             ++    T V            G ++   ++ K+++  +  K P+Q+  D       F  
Sbjct: 214  SNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYS 273

Query: 927  FIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCS 986
            F II   + LV W++                 K I +        F  S+++   A P  
Sbjct: 274  FGII-GIIMLVGWLL----------------GKDILEM-------FTISVSLAVAAIPEG 309

Query: 987  LGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTIT 1033
            L +     + +G     +   ++K    +E       +  DKTGT+T
Sbjct: 310  LPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLT 356


>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
            sapiens]
          Length = 999

 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 31/158 (19%)

Query: 1185 DGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI-------- 1236
            D    G + + D  + E A  +      G+ VV+ITGDN+ TA AI  ++GI        
Sbjct: 590  DLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVA 649

Query: 1237 -----------------------NKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSP 1273
                                    + FA V P+HK   V+ LQ+  +  AM GDGVND+P
Sbjct: 650  GKAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAP 709

Query: 1274 ALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASI 1311
            AL +A++G+A+G+GT VA  AA++VL  ++   +VA++
Sbjct: 710  ALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAV 747



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 76/338 (22%), Positives = 141/338 (41%), Gaps = 51/338 (15%)

Query: 735  LATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIA---LGRWLEHLAKSKTSEA 791
            L   I  + +LV  V+A  E+ E +   F +   ++ + +A   +G W E  A+S     
Sbjct: 60   LLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAES----- 114

Query: 792  LAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQR-----GDIVKVVPGGKFPVDGKVL 846
                    A EA      E   +IR ++  ++ ++      GDIV+V  G K P D +++
Sbjct: 115  --------AIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLI 166

Query: 847  EGNTMA---DESLITGEAMPVTKKPGST-------------VIAGSINAHGSVLIKATHV 890
            E  +     D+S++TGE++ VTK   +              + +G+    G  +  A   
Sbjct: 167  EIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVAT 226

Query: 891  GNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIV-IGFIDFGV 949
            G  T L +I   +   +  + P+Q+  D F       I   S + + VW++ IG      
Sbjct: 227  GLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAI---SVICVAVWVINIG------ 277

Query: 950  VQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILI 1009
               +F +P    S     + + F+ ++ +   A P  L     T + +GT   A+   ++
Sbjct: 278  ---HFADPAHGGSWLRGAVYY-FKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIV 333

Query: 1010 KGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGD 1047
            +    +E       +  DKTGT+T     V R+ ++ +
Sbjct: 334  RSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAE 371


>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
            sapiens]
          Length = 1029

 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 31/158 (19%)

Query: 1185 DGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI-------- 1236
            D    G + + D  + E A  +      G+ VV+ITGDN+ TA AI  ++GI        
Sbjct: 590  DLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVA 649

Query: 1237 -----------------------NKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSP 1273
                                    + FA V P+HK   V+ LQ+  +  AM GDGVND+P
Sbjct: 650  GKAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAP 709

Query: 1274 ALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASI 1311
            AL +A++G+A+G+GT VA  AA++VL  ++   +VA++
Sbjct: 710  ALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAV 747



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 76/338 (22%), Positives = 141/338 (41%), Gaps = 51/338 (15%)

Query: 735  LATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIA---LGRWLEHLAKSKTSEA 791
            L   I  + +LV  V+A  E+ E +   F +   ++ + +A   +G W E  A+S     
Sbjct: 60   LLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAES----- 114

Query: 792  LAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQR-----GDIVKVVPGGKFPVDGKVL 846
                    A EA      E   +IR ++  ++ ++      GDIV+V  G K P D +++
Sbjct: 115  --------AIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLI 166

Query: 847  EGNTMA---DESLITGEAMPVTKKPGST-------------VIAGSINAHGSVLIKATHV 890
            E  +     D+S++TGE++ VTK   +              + +G+    G  +  A   
Sbjct: 167  EIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVAT 226

Query: 891  GNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIV-IGFIDFGV 949
            G  T L +I   +   +  + P+Q+  D F       I   S + + VW++ IG      
Sbjct: 227  GLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAI---SVICVAVWVINIG------ 277

Query: 950  VQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILI 1009
               +F +P    S     + + F+ ++ +   A P  L     T + +GT   A+   ++
Sbjct: 278  ---HFADPAHGGSWLRGAVYY-FKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIV 333

Query: 1010 KGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGD 1047
            +    +E       +  DKTGT+T     V R+ ++ +
Sbjct: 334  RSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAE 371


>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
            sapiens]
          Length = 998

 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 31/158 (19%)

Query: 1185 DGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI-------- 1236
            D    G + + D  + E A  +      G+ VV+ITGDN+ TA AI  ++GI        
Sbjct: 590  DLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVA 649

Query: 1237 -----------------------NKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSP 1273
                                    + FA V P+HK   V+ LQ+  +  AM GDGVND+P
Sbjct: 650  GKAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAP 709

Query: 1274 ALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASI 1311
            AL +A++G+A+G+GT VA  AA++VL  ++   +VA++
Sbjct: 710  ALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAV 747



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 76/338 (22%), Positives = 141/338 (41%), Gaps = 51/338 (15%)

Query: 735  LATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIA---LGRWLEHLAKSKTSEA 791
            L   I  + +LV  V+A  E+ E +   F +   ++ + +A   +G W E  A+S     
Sbjct: 60   LLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAES----- 114

Query: 792  LAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQR-----GDIVKVVPGGKFPVDGKVL 846
                    A EA      E   +IR ++  ++ ++      GDIV+V  G K P D +++
Sbjct: 115  --------AIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLI 166

Query: 847  EGNTMA---DESLITGEAMPVTKKPGST-------------VIAGSINAHGSVLIKATHV 890
            E  +     D+S++TGE++ VTK   +              + +G+    G  +  A   
Sbjct: 167  EIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVAT 226

Query: 891  GNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIV-IGFIDFGV 949
            G  T L +I   +   +  + P+Q+  D F       I   S + + VW++ IG      
Sbjct: 227  GLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAI---SVICVAVWVINIG------ 277

Query: 950  VQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILI 1009
               +F +P    S     + + F+ ++ +   A P  L     T + +GT   A+   ++
Sbjct: 278  ---HFADPAHGGSWLRGAVYY-FKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIV 333

Query: 1010 KGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGD 1047
            +    +E       +  DKTGT+T     V R+ ++ +
Sbjct: 334  RSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAE 371


>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
            sapiens]
          Length = 1029

 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 31/158 (19%)

Query: 1185 DGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI-------- 1236
            D    G + + D  + E A  +      G+ VV+ITGDN+ TA AI  ++GI        
Sbjct: 590  DLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVA 649

Query: 1237 -----------------------NKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSP 1273
                                    + FA V P+HK   V+ LQ+  +  AM GDGVND+P
Sbjct: 650  GKAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAP 709

Query: 1274 ALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASI 1311
            AL +A++G+A+G+GT VA  AA++VL  ++   +VA++
Sbjct: 710  ALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAV 747



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 76/338 (22%), Positives = 141/338 (41%), Gaps = 51/338 (15%)

Query: 735  LATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIA---LGRWLEHLAKSKTSEA 791
            L   I  + +LV  V+A  E+ E +   F +   ++ + +A   +G W E  A+S     
Sbjct: 60   LLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAES----- 114

Query: 792  LAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQR-----GDIVKVVPGGKFPVDGKVL 846
                    A EA      E   +IR ++  ++ ++      GDIV+V  G K P D +++
Sbjct: 115  --------AIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLI 166

Query: 847  EGNTMA---DESLITGEAMPVTKKPGST-------------VIAGSINAHGSVLIKATHV 890
            E  +     D+S++TGE++ VTK   +              + +G+    G  +  A   
Sbjct: 167  EIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVAT 226

Query: 891  GNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIV-IGFIDFGV 949
            G  T L +I   +   +  + P+Q+  D F       I   S + + VW++ IG      
Sbjct: 227  GLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAI---SVICVAVWVINIG------ 277

Query: 950  VQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILI 1009
               +F +P    S     + + F+ ++ +   A P  L     T + +GT   A+   ++
Sbjct: 278  ---HFADPAHGGSWLRGAVYY-FKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIV 333

Query: 1010 KGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGD 1047
            +    +E       +  DKTGT+T     V R+ ++ +
Sbjct: 334  RSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAE 371


>gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo
            sapiens]
          Length = 1043

 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 31/158 (19%)

Query: 1185 DGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI-------- 1236
            D    G + + D  + E A  +      G+ VV+ITGDN+ TA AI  ++GI        
Sbjct: 590  DLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVA 649

Query: 1237 -----------------------NKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSP 1273
                                    + FA V P+HK   V+ LQ+  +  AM GDGVND+P
Sbjct: 650  GKAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAP 709

Query: 1274 ALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASI 1311
            AL +A++G+A+G+GT VA  AA++VL  ++   +VA++
Sbjct: 710  ALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAV 747



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 76/338 (22%), Positives = 141/338 (41%), Gaps = 51/338 (15%)

Query: 735  LATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIA---LGRWLEHLAKSKTSEA 791
            L   I  + +LV  V+A  E+ E +   F +   ++ + +A   +G W E  A+S     
Sbjct: 60   LLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAES----- 114

Query: 792  LAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQR-----GDIVKVVPGGKFPVDGKVL 846
                    A EA      E   +IR ++  ++ ++      GDIV+V  G K P D +++
Sbjct: 115  --------AIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLI 166

Query: 847  EGNTMA---DESLITGEAMPVTKKPGST-------------VIAGSINAHGSVLIKATHV 890
            E  +     D+S++TGE++ VTK   +              + +G+    G  +  A   
Sbjct: 167  EIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVAT 226

Query: 891  GNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIV-IGFIDFGV 949
            G  T L +I   +   +  + P+Q+  D F       I   S + + VW++ IG      
Sbjct: 227  GLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAI---SVICVAVWVINIG------ 277

Query: 950  VQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILI 1009
               +F +P    S     + + F+ ++ +   A P  L     T + +GT   A+   ++
Sbjct: 278  ---HFADPAHGGSWLRGAVYY-FKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIV 333

Query: 1010 KGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGD 1047
            +    +E       +  DKTGT+T     V R+ ++ +
Sbjct: 334  RSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAE 371


>gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo
            sapiens]
          Length = 1044

 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 31/158 (19%)

Query: 1185 DGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI-------- 1236
            D    G + + D  + E A  +      G+ VV+ITGDN+ TA AI  ++GI        
Sbjct: 590  DLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVA 649

Query: 1237 -----------------------NKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSP 1273
                                    + FA V P+HK   V+ LQ+  +  AM GDGVND+P
Sbjct: 650  GKAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAP 709

Query: 1274 ALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASI 1311
            AL +A++G+A+G+GT VA  AA++VL  ++   +VA++
Sbjct: 710  ALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAV 747



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 76/338 (22%), Positives = 141/338 (41%), Gaps = 51/338 (15%)

Query: 735  LATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIA---LGRWLEHLAKSKTSEA 791
            L   I  + +LV  V+A  E+ E +   F +   ++ + +A   +G W E  A+S     
Sbjct: 60   LLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAES----- 114

Query: 792  LAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQR-----GDIVKVVPGGKFPVDGKVL 846
                    A EA      E   +IR ++  ++ ++      GDIV+V  G K P D +++
Sbjct: 115  --------AIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLI 166

Query: 847  EGNTMA---DESLITGEAMPVTKKPGST-------------VIAGSINAHGSVLIKATHV 890
            E  +     D+S++TGE++ VTK   +              + +G+    G  +  A   
Sbjct: 167  EIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVAT 226

Query: 891  GNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIV-IGFIDFGV 949
            G  T L +I   +   +  + P+Q+  D F       I   S + + VW++ IG      
Sbjct: 227  GLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAI---SVICVAVWVINIG------ 277

Query: 950  VQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILI 1009
               +F +P    S     + + F+ ++ +   A P  L     T + +GT   A+   ++
Sbjct: 278  ---HFADPAHGGSWLRGAVYY-FKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIV 333

Query: 1010 KGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGD 1047
            +    +E       +  DKTGT+T     V R+ ++ +
Sbjct: 334  RSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAE 371


>gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo
            sapiens]
          Length = 1052

 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 31/158 (19%)

Query: 1185 DGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI-------- 1236
            D    G + + D  + E A  +      G+ VV+ITGDN+ TA AI  ++GI        
Sbjct: 590  DLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVA 649

Query: 1237 -----------------------NKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSP 1273
                                    + FA V P+HK   V+ LQ+  +  AM GDGVND+P
Sbjct: 650  GKAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAP 709

Query: 1274 ALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASI 1311
            AL +A++G+A+G+GT VA  AA++VL  ++   +VA++
Sbjct: 710  ALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAV 747



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 76/338 (22%), Positives = 141/338 (41%), Gaps = 51/338 (15%)

Query: 735  LATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIA---LGRWLEHLAKSKTSEA 791
            L   I  + +LV  V+A  E+ E +   F +   ++ + +A   +G W E  A+S     
Sbjct: 60   LLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAES----- 114

Query: 792  LAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQR-----GDIVKVVPGGKFPVDGKVL 846
                    A EA      E   +IR ++  ++ ++      GDIV+V  G K P D +++
Sbjct: 115  --------AIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLI 166

Query: 847  EGNTMA---DESLITGEAMPVTKKPGST-------------VIAGSINAHGSVLIKATHV 890
            E  +     D+S++TGE++ VTK   +              + +G+    G  +  A   
Sbjct: 167  EIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVAT 226

Query: 891  GNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIV-IGFIDFGV 949
            G  T L +I   +   +  + P+Q+  D F       I   S + + VW++ IG      
Sbjct: 227  GLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAI---SVICVAVWVINIG------ 277

Query: 950  VQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILI 1009
               +F +P    S     + + F+ ++ +   A P  L     T + +GT   A+   ++
Sbjct: 278  ---HFADPAHGGSWLRGAVYY-FKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIV 333

Query: 1010 KGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGD 1047
            +    +E       +  DKTGT+T     V R+ ++ +
Sbjct: 334  RSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAE 371


>gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo
            sapiens]
          Length = 997

 Score = 85.1 bits (209), Expect = 4e-16
 Identities = 52/153 (33%), Positives = 82/153 (53%), Gaps = 31/153 (20%)

Query: 1190 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI------------- 1236
            G + + D  + E A +V   +  G+ V++ITGDN+ TA AI  ++GI             
Sbjct: 594  GCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFT 653

Query: 1237 ------------------NKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQA 1278
                               + FA V PSHK   V+ LQ+  +  AM GDGVND+PAL +A
Sbjct: 654  GREFDELNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKA 713

Query: 1279 DMGVAIGTGTDVAIEAADVVLIRNDLLDVVASI 1311
            ++G+A+G+GT VA  A+++VL  ++   +VA++
Sbjct: 714  EIGIAMGSGTAVAKTASEMVLADDNFSTIVAAV 746



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 76/346 (21%), Positives = 145/346 (41%), Gaps = 55/346 (15%)

Query: 735  LATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIA---LGRWLEHLAKSKTSEA 791
            L   I  + + +  V+A  E+ E +   F +   +L + +A   +G W E  A++     
Sbjct: 60   LLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAEN----- 114

Query: 792  LAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQR-----GDIVKVVPGGKFPVDGKV- 845
                    A EA      E   + R+++  ++ ++      GDIV++  G K P D ++ 
Sbjct: 115  --------AIEALKEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLT 166

Query: 846  -LEGNTM-ADESLITGEAMPVTKKPG-------------STVIAGSINAHGSVLIKATHV 890
             ++  T+  D+S++TGE++ V K                + + +G+  A G  +      
Sbjct: 167  SIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVAT 226

Query: 891  GNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIV-IGFIDFGV 949
            G +T + +I   +   +  + P+QQ  D F         ++S + + VWI+ IG      
Sbjct: 227  GVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSK---VISLICIAVWIINIG------ 277

Query: 950  VQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILI 1009
               +F +P    S     I + F+ ++ +   A P  L     T + +GT   A+   ++
Sbjct: 278  ---HFNDPVHGGSWIRGAIYY-FKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIV 333

Query: 1010 KGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLL----GDVATL 1051
            +    +E       +  DKTGT+T     V R+ +L    GD  +L
Sbjct: 334  RSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSL 379


>gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [Homo
            sapiens]
          Length = 1042

 Score = 85.1 bits (209), Expect = 4e-16
 Identities = 52/153 (33%), Positives = 82/153 (53%), Gaps = 31/153 (20%)

Query: 1190 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI------------- 1236
            G + + D  + E A +V   +  G+ V++ITGDN+ TA AI  ++GI             
Sbjct: 594  GCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFT 653

Query: 1237 ------------------NKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQA 1278
                               + FA V PSHK   V+ LQ+  +  AM GDGVND+PAL +A
Sbjct: 654  GREFDELNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKA 713

Query: 1279 DMGVAIGTGTDVAIEAADVVLIRNDLLDVVASI 1311
            ++G+A+G+GT VA  A+++VL  ++   +VA++
Sbjct: 714  EIGIAMGSGTAVAKTASEMVLADDNFSTIVAAV 746



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 76/346 (21%), Positives = 145/346 (41%), Gaps = 55/346 (15%)

Query: 735  LATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIA---LGRWLEHLAKSKTSEA 791
            L   I  + + +  V+A  E+ E +   F +   +L + +A   +G W E  A++     
Sbjct: 60   LLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAEN----- 114

Query: 792  LAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQR-----GDIVKVVPGGKFPVDGKV- 845
                    A EA      E   + R+++  ++ ++      GDIV++  G K P D ++ 
Sbjct: 115  --------AIEALKEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLT 166

Query: 846  -LEGNTM-ADESLITGEAMPVTKKPG-------------STVIAGSINAHGSVLIKATHV 890
             ++  T+  D+S++TGE++ V K                + + +G+  A G  +      
Sbjct: 167  SIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVAT 226

Query: 891  GNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIV-IGFIDFGV 949
            G +T + +I   +   +  + P+QQ  D F         ++S + + VWI+ IG      
Sbjct: 227  GVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSK---VISLICIAVWIINIG------ 277

Query: 950  VQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILI 1009
               +F +P    S     I + F+ ++ +   A P  L     T + +GT   A+   ++
Sbjct: 278  ---HFNDPVHGGSWIRGAIYY-FKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIV 333

Query: 1010 KGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLL----GDVATL 1051
            +    +E       +  DKTGT+T     V R+ +L    GD  +L
Sbjct: 334  RSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSL 379


>gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 [Homo
            sapiens]
          Length = 1015

 Score = 85.1 bits (209), Expect = 4e-16
 Identities = 52/153 (33%), Positives = 82/153 (53%), Gaps = 31/153 (20%)

Query: 1190 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI------------- 1236
            G + + D  + E A +V   +  G+ V++ITGDN+ TA AI  ++GI             
Sbjct: 567  GCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFT 626

Query: 1237 ------------------NKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQA 1278
                               + FA V PSHK   V+ LQ+  +  AM GDGVND+PAL +A
Sbjct: 627  GREFDELNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKA 686

Query: 1279 DMGVAIGTGTDVAIEAADVVLIRNDLLDVVASI 1311
            ++G+A+G+GT VA  A+++VL  ++   +VA++
Sbjct: 687  EIGIAMGSGTAVAKTASEMVLADDNFSTIVAAV 719



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 68/325 (20%), Positives = 130/325 (40%), Gaps = 40/325 (12%)

Query: 735  LATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIA---LGRWLEHLAKSKTSEA 791
            L   I  + + +  V+A  E+ E +   F +   +L + +A   +G W E  A++     
Sbjct: 60   LLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAEN----- 114

Query: 792  LAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTM 851
                    A EA      E   + R+++  ++ ++  DIV   PG    + G+ +     
Sbjct: 115  --------AIEALKEYEPEMGKVYRQDRKSVQRIKAKDIV---PGDIVEIAGESVSVIKH 163

Query: 852  ADESLITGEAMPVTKKPGSTVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKA 911
             D      +   V +   + + +G+  A G  +      G +T + +I   +   +  + 
Sbjct: 164  TDP---VPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERT 220

Query: 912  PIQQLADRFSGYFVPFIIIMSTLTLVVWIV-IGFIDFGVVQRYFPNPNKHISQTEVIIRF 970
            P+QQ  D F         ++S + + VWI+ IG         +F +P    S     I +
Sbjct: 221  PLQQKLDEFGEQLSK---VISLICIAVWIINIG---------HFNDPVHGGSWIRGAIYY 268

Query: 971  AFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTG 1030
             F+ ++ +   A P  L     T + +GT   A+   +++    +E       +  DKTG
Sbjct: 269  -FKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTG 327

Query: 1031 TITHGVPRVMRVLLL----GDVATL 1051
            T+T     V R+ +L    GD  +L
Sbjct: 328  TLTTNQMSVCRMFILDRVEGDTCSL 352


>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [Homo
            sapiens]
          Length = 994

 Score = 85.1 bits (209), Expect = 4e-16
 Identities = 57/195 (29%), Positives = 99/195 (50%), Gaps = 32/195 (16%)

Query: 1185 DGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI---NK--- 1238
            D    G++ + D  ++E   ++   +  G+ V++ITGDN+ TA AI  ++GI   N+   
Sbjct: 590  DLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVA 649

Query: 1239 -------------------------VFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSP 1273
                                      FA V PSHK   V+ LQ+  +  AM GDGVND+P
Sbjct: 650  DRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAP 709

Query: 1274 ALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVLALIYNL 1333
            AL +A++G+A+G+GT VA  A+++VL  ++   +VA++   +     ++   +  LI + 
Sbjct: 710  ALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMK-QFIRYLISSN 768

Query: 1334 VGIPIAAGVFMPIGI 1348
            VG  +   +   +G+
Sbjct: 769  VGEVVCIFLTAALGL 783



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 80/364 (21%), Positives = 152/364 (41%), Gaps = 58/364 (15%)

Query: 712  WYFYVQAYKSLRHRSANMDVLIVLATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLF 771
            W   ++ ++ L  R      +++LA  I++V       +A  E+ E +   F +   +L 
Sbjct: 50   WELVIEQFEDLLVR------ILLLAACISFV-------LAWFEEGEETITAFVEPFVILL 96

Query: 772  VFIA---LGRWLEHLAKSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRG 828
            + IA   +G W E  A++    A+  L   +     V      ++    +++    +  G
Sbjct: 97   ILIANAIVGVWQERNAEN----AIEALKEYEPEMGKVYRADRKSV----QRIKARDIVPG 148

Query: 829  DIVKVVPGGKFPVDGKVL--EGNTM-ADESLITGEAMPVTKKPG-------------STV 872
            DIV+V  G K P D ++L  +  T+  D+S++TGE++ V K                + +
Sbjct: 149  DIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNML 208

Query: 873  IAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMS 932
             +G+  A G  L      G  T + +I   +   +  K P+QQ  D F         ++S
Sbjct: 209  FSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSK---VIS 265

Query: 933  TLTLVVWIV-IGFIDFGVVQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLAT 991
             + + VW++ IG         +F +P    S     I + F+ ++ +   A P  L    
Sbjct: 266  LICVAVWLINIG---------HFNDPVHGGSWFRGAIYY-FKIAVALAVAAIPEGLPAVI 315

Query: 992  PTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLL----GD 1047
             T + +GT   A+   +++    +E       +  DKTGT+T     V ++ ++    GD
Sbjct: 316  TTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGD 375

Query: 1048 VATL 1051
            +  L
Sbjct: 376  ICLL 379


>gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [Homo
            sapiens]
          Length = 1001

 Score = 85.1 bits (209), Expect = 4e-16
 Identities = 57/195 (29%), Positives = 99/195 (50%), Gaps = 32/195 (16%)

Query: 1185 DGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI---NK--- 1238
            D    G++ + D  ++E   ++   +  G+ V++ITGDN+ TA AI  ++GI   N+   
Sbjct: 590  DLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVA 649

Query: 1239 -------------------------VFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSP 1273
                                      FA V PSHK   V+ LQ+  +  AM GDGVND+P
Sbjct: 650  DRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAP 709

Query: 1274 ALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVLALIYNL 1333
            AL +A++G+A+G+GT VA  A+++VL  ++   +VA++   +     ++   +  LI + 
Sbjct: 710  ALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMK-QFIRYLISSN 768

Query: 1334 VGIPIAAGVFMPIGI 1348
            VG  +   +   +G+
Sbjct: 769  VGEVVCIFLTAALGL 783



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 80/364 (21%), Positives = 152/364 (41%), Gaps = 58/364 (15%)

Query: 712  WYFYVQAYKSLRHRSANMDVLIVLATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLF 771
            W   ++ ++ L  R      +++LA  I++V       +A  E+ E +   F +   +L 
Sbjct: 50   WELVIEQFEDLLVR------ILLLAACISFV-------LAWFEEGEETITAFVEPFVILL 96

Query: 772  VFIA---LGRWLEHLAKSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRG 828
            + IA   +G W E  A++    A+  L   +     V      ++    +++    +  G
Sbjct: 97   ILIANAIVGVWQERNAEN----AIEALKEYEPEMGKVYRADRKSV----QRIKARDIVPG 148

Query: 829  DIVKVVPGGKFPVDGKVL--EGNTM-ADESLITGEAMPVTKKPG-------------STV 872
            DIV+V  G K P D ++L  +  T+  D+S++TGE++ V K                + +
Sbjct: 149  DIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNML 208

Query: 873  IAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMS 932
             +G+  A G  L      G  T + +I   +   +  K P+QQ  D F         ++S
Sbjct: 209  FSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSK---VIS 265

Query: 933  TLTLVVWIV-IGFIDFGVVQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLAT 991
             + + VW++ IG         +F +P    S     I + F+ ++ +   A P  L    
Sbjct: 266  LICVAVWLINIG---------HFNDPVHGGSWFRGAIYY-FKIAVALAVAAIPEGLPAVI 315

Query: 992  PTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLL----GD 1047
             T + +GT   A+   +++    +E       +  DKTGT+T     V ++ ++    GD
Sbjct: 316  TTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGD 375

Query: 1048 VATL 1051
            +  L
Sbjct: 376  ICLL 379


>gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo
            sapiens]
          Length = 946

 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 55/154 (35%), Positives = 78/154 (50%), Gaps = 28/154 (18%)

Query: 1190 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAI------------------- 1230
            G++ I D  +     AV  L   GV V +ITGD  +TA AI                   
Sbjct: 570  GLVGIIDPPRVGVKEAVQVLSESGVSVKMITGDALETALAIGRNIGLCNGKLQAMSGEEV 629

Query: 1231 --------ATQVGINKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGV 1282
                    A +VG   VF    P HK+  ++ LQ  G  VAM GDGVND+ AL  AD+G+
Sbjct: 630  DSVEKGELADRVGKVSVFFRTSPKHKLKIIKALQESGAIVAMTGDGVNDAVALKSADIGI 689

Query: 1283 AIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSK 1315
            A+G TGTDV+ EAA+++L+ +D   ++ ++   K
Sbjct: 690  AMGQTGTDVSKEAANMILVDDDFSAIMNAVEEGK 723



 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 53/261 (20%), Positives = 104/261 (39%), Gaps = 43/261 (16%)

Query: 787  KTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGKVL 846
            ++ ++L +L  +   E   +  G+   ++  E VP      GD+V +  G + P D ++ 
Sbjct: 154  RSEKSLEELTKMVPPECNCLREGKLQHLLARELVP------GDVVSLSIGDRIPADIRLT 207

Query: 847  E-GNTMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLIKATHV------------GND 893
            E  + + DES  TGEA P +K        G +    +++   T V            G  
Sbjct: 208  EVTDLLVDESSFTGEAEPCSKTDSPLTGGGDLTTLSNIVFMGTLVQYGRGQGVVIGTGES 267

Query: 894  TTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFII-IMSTLTLVVWIVIGFIDFGVVQR 952
            +   ++ K+++  +  K P+Q+  DR       F   I+  + L+ W             
Sbjct: 268  SQFGEVFKMMQAEETPKTPLQKSMDRLGKQLTLFSFGIIGLIMLIGW------------- 314

Query: 953  YFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGG 1012
                     SQ + ++   F   +++   A P  L +     +++G    A+  +++K  
Sbjct: 315  ---------SQGKQLLSM-FTIGVSLAVAAIPEGLPIVVMVTLVLGVLRMAKKRVIVKKL 364

Query: 1013 KPLEMAHKIKTVMFDKTGTIT 1033
              +E       +  DKTGT+T
Sbjct: 365  PIVETLGCCSVLCSDKTGTLT 385


>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
          Length = 1039

 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 70/243 (28%), Positives = 107/243 (44%), Gaps = 69/243 (28%)

Query: 1190 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI------------- 1236
            G++++ D  +     AV   +S G+ V+++TGD+  TA+AIA  VGI             
Sbjct: 602  GLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAH 661

Query: 1237 ---------NK-------------------------------VFAEVLPSHKVAKVQELQ 1256
                     NK                               VFA   P  K+  V+  Q
Sbjct: 662  RLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQ 721

Query: 1257 NKGKKVAMVGDGVNDSPALAQADMGVAIG-TGTDVAIEAADVVLIRNDLLDVVASI---- 1311
             +   VA+ GDGVNDSPAL +AD+G+A+G  G+D A  AAD+VL+ ++   +V  +    
Sbjct: 722  RQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGR 781

Query: 1312 ----HLSKRTVRRIRIN---LVLALIYNLVGIPIAAG----VFMPIGIVLQPWMGSAAMA 1360
                +L K     +  N   L   LIY +VG+P+  G    +F+ +G  + P +  A   
Sbjct: 782  LIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEK 841

Query: 1361 ASS 1363
            A S
Sbjct: 842  AES 844



 Score = 40.8 bits (94), Expect = 0.010
 Identities = 54/236 (22%), Positives = 88/236 (37%), Gaps = 38/236 (16%)

Query: 813  LIIREEQ---VPMELVQRGDIVKVVPGGKFPVDGKVLEG-NTMADESLITGEAMPVTKKP 868
            L+IR+ +   +P E +  GDIV+V  G + P D +VL       D S +TGE+ P  +  
Sbjct: 185  LVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSS 244

Query: 869  GST----------VIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLAD 918
              T              +    G+V     + G+ T +  I  L       K PI    +
Sbjct: 245  EFTHENPLETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIE 304

Query: 919  RFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNKHISQTEVIIRFAFQTSITV 978
             F        + +  L  ++ + + +                    +V+    F   I V
Sbjct: 305  HFVHIVAGVAVSIGILFFIIAVSLKY--------------------QVLDSIIFLIGIIV 344

Query: 979  LCIACPCSLGLATPTAVMVGTGV-AAQNGILIKGGKPLEMAHKIKTVMFDKTGTIT 1033
              +  P  L LAT T  +  T    A+   L+K  + +E       +  DKTGT+T
Sbjct: 345  ANV--PEGL-LATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLT 397


>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
            sapiens]
          Length = 1176

 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 59/200 (29%), Positives = 92/200 (46%), Gaps = 44/200 (22%)

Query: 1184 IDGVLC-GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGIN----- 1237
            + G+ C  ++ I D V+ E   A+   Q  G+ V ++TGDN  TARAIAT+ GI      
Sbjct: 671  VTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGED 730

Query: 1238 --------------------------------KVFAEVLPSHKVAKVQEL-----QNKGK 1260
                                            +V A   P+ K   V+ +      ++ +
Sbjct: 731  FLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQ 790

Query: 1261 KVAMVGDGVNDSPALAQADMGVAIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVR 1319
             VA+ GDG ND PAL +AD+G A+G  GTDVA EA+D++L  ++   +V ++   +    
Sbjct: 791  VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYD 850

Query: 1320 RIRINLVLALIYNLVGIPIA 1339
             I   L   L  N+V + +A
Sbjct: 851  SISKFLQFQLTVNVVAVIVA 870



 Score = 39.3 bits (90), Expect = 0.028
 Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 13/85 (15%)

Query: 819 QVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTM-ADESLITGEAMPVTKK--------PG 869
           Q+P+  +  GDI +V  G   P DG +++GN +  DES +TGE+  V K          G
Sbjct: 204 QIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPLLLSG 263

Query: 870 STVIAGSINAHGSVLIKATHVGNDT 894
           + V+ GS    G +++ A  V + T
Sbjct: 264 THVMEGS----GRMVVTAVGVNSQT 284



 Score = 32.0 bits (71), Expect = 4.5
 Identities = 25/105 (23%), Positives = 47/105 (44%), Gaps = 1/105 (0%)

Query: 929  IIMSTLTLVVWIVIGFIDFGVVQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLG 988
            ++MS +T+++ ++   ID   VQ+            +  ++F F   +TVL +A P  L 
Sbjct: 378  LLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKF-FIIGVTVLVVAVPEGLP 436

Query: 989  LATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTIT 1033
            LA   ++        ++  L++     E       +  DKTGT+T
Sbjct: 437  LAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLT 481


>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
            sapiens]
          Length = 1220

 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 59/200 (29%), Positives = 92/200 (46%), Gaps = 44/200 (22%)

Query: 1184 IDGVLC-GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGIN----- 1237
            + G+ C  ++ I D V+ E   A+   Q  G+ V ++TGDN  TARAIAT+ GI      
Sbjct: 671  VTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGED 730

Query: 1238 --------------------------------KVFAEVLPSHKVAKVQEL-----QNKGK 1260
                                            +V A   P+ K   V+ +      ++ +
Sbjct: 731  FLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQ 790

Query: 1261 KVAMVGDGVNDSPALAQADMGVAIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVR 1319
             VA+ GDG ND PAL +AD+G A+G  GTDVA EA+D++L  ++   +V ++   +    
Sbjct: 791  VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYD 850

Query: 1320 RIRINLVLALIYNLVGIPIA 1339
             I   L   L  N+V + +A
Sbjct: 851  SISKFLQFQLTVNVVAVIVA 870



 Score = 39.3 bits (90), Expect = 0.028
 Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 13/85 (15%)

Query: 819 QVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTM-ADESLITGEAMPVTKK--------PG 869
           Q+P+  +  GDI +V  G   P DG +++GN +  DES +TGE+  V K          G
Sbjct: 204 QIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPLLLSG 263

Query: 870 STVIAGSINAHGSVLIKATHVGNDT 894
           + V+ GS    G +++ A  V + T
Sbjct: 264 THVMEGS----GRMVVTAVGVNSQT 284



 Score = 32.0 bits (71), Expect = 4.5
 Identities = 25/105 (23%), Positives = 47/105 (44%), Gaps = 1/105 (0%)

Query: 929  IIMSTLTLVVWIVIGFIDFGVVQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLG 988
            ++MS +T+++ ++   ID   VQ+            +  ++F F   +TVL +A P  L 
Sbjct: 378  LLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKF-FIIGVTVLVVAVPEGLP 436

Query: 989  LATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTIT 1033
            LA   ++        ++  L++     E       +  DKTGT+T
Sbjct: 437  LAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLT 481


>gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens]
          Length = 1158

 Score = 77.8 bits (190), Expect = 7e-14
 Identities = 130/634 (20%), Positives = 223/634 (35%), Gaps = 159/634 (25%)

Query: 770  LFVFIALGRWLEHLAKSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGD 829
            +F+  ++   L      K S+ L  ++ L          GE+  +   E VP      GD
Sbjct: 258  IFLISSISICLSLYKTRKQSQTLRDMVKLSMRVCVCRPGGEEEWVDSSELVP------GD 311

Query: 830  IVKVVP--GGKFPVDGKVLEGNTMADESLITGEAMPVTKKP------------------- 868
             + V+P  GG  P D  ++ G  M +ES +TGE++PV K                     
Sbjct: 312  CL-VLPQEGGLMPCDAALVAGECMVNESSLTGESIPVLKTALPEGLGPYCAETHRRHTLF 370

Query: 869  -GSTVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPF 927
             G+ ++         VL   T  G  T    +V  +    +   PI     +F  + + F
Sbjct: 371  CGTLILQARAYVGPHVLAVVTRTGFCTAKGGLVSSI----LHPRPIN---FKFYKHSMKF 423

Query: 928  IIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSL 987
            +  +S L L+          G +   F      +   E++IR     ++ ++ +  P +L
Sbjct: 424  VAALSVLALL----------GTIYSIFILYRNRVPLNEIVIR-----ALDLVTVVVPPAL 468

Query: 988  GLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVL---- 1043
              A     +       + GI       + +  K++ V FDKTGT+T     VM V+    
Sbjct: 469  PAAMTVCTLYAQSRLRRQGIFCIHPLRINLGGKLQLVCFDKTGTLTEDGLDVMGVVPLKG 528

Query: 1044 -----LLGDVATLPLRKVLAVVGTAEASS---EHPLGVAVTKYCKEELGTETLGYCTDFQ 1095
                 L+ +   LP+  +L  + T  A S   + P+G  +     +    E+ G+  + +
Sbjct: 529  QAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPM-----DLKMVESTGWVLEEE 583

Query: 1096 AVPGCGIGCKVSNVEGILAHSERPLSAPASHLNEAGSLPAEK------DAVPQTFSVLI- 1148
                   G +V      LA    PL  P     E   +P          +  Q  SV++ 
Sbjct: 584  PAADSAFGTQV------LAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVA 637

Query: 1149 ------------GNREWLRR--NGLTISSDVSDAMTDHEMKGQTAILVAI---------- 1184
                        G+ E +    N  T+ +D +  +  +   G   + +A           
Sbjct: 638  WPGATQPEAYVKGSPELVAGLCNPETVPTDFAQMLQSYTAAGYRVVALASKPLPTVPSLE 697

Query: 1185 ------------DGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIAT 1232
                        D  L G++ + + +K +    +  L+   +  V++TGDN +TA  +A 
Sbjct: 698  AAQQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVAR 757

Query: 1233 QVGI------------------------------------------NKVFAEVLPSHKVA 1250
              G+                                            VFA + P  K  
Sbjct: 758  GCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTAVNGVKVLVQGTVFARMAPEQKTE 817

Query: 1251 KVQELQNKGKKVAMVGDGVNDSPALAQADMGVAI 1284
             V ELQ     V M GDG ND  AL  AD+G+++
Sbjct: 818  LVCELQKLQYCVGMCGDGANDCGALKAADVGISL 851


>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapiens]
          Length = 1029

 Score = 77.4 bits (189), Expect = 9e-14
 Identities = 58/219 (26%), Positives = 101/219 (46%), Gaps = 59/219 (26%)

Query: 1190 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIAT----------------- 1232
            G+I++ D  +     AV   +S G+ V+++TGD+  TA+AIA                  
Sbjct: 593  GLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTETAEEVAA 652

Query: 1233 --QVGINKV----------------------------------FAEVLPSHKVAKVQELQ 1256
              ++ I+KV                                  FA   P  K+  V+  Q
Sbjct: 653  RLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFARTSPQQKLIIVEGCQ 712

Query: 1257 NKGKKVAMVGDGVNDSPALAQADMGVAIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSK 1315
              G  VA+ GDGVNDSPAL +AD+G+A+G +G+DV+ +AAD++L+ ++   +V  +   +
Sbjct: 713  RLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGR 772

Query: 1316 RTVRRIRINLVLALIYNLVGIP-----IAAGVFMPIGIV 1349
                 ++ +++  L  N+  I      I  G+ +P+G +
Sbjct: 773  LIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTI 811



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 57/277 (20%), Positives = 109/277 (39%), Gaps = 41/277 (14%)

Query: 769  MLFVFIALGRWLEHLAKSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRG 828
            +L V + +     +  ++K+S+ +    ++   +A V+  GE      + Q+ ++ V  G
Sbjct: 143  VLSVVVIVTGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGE------KMQINVQEVVLG 196

Query: 829  DIVKVVPGGKFPVDGKVLEGN-TMADESLITGEAMPVTKKPGST---------VIAGSIN 878
            D+V++  G + P D +++       D S +TGE+ P ++ P  T         +   S N
Sbjct: 197  DLVEIKGGDRVPADLRLISAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTN 256

Query: 879  A-HGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLV 937
               G+        G+ T + +I  L     + + PI    + F        + +      
Sbjct: 257  CVEGTARGIVIATGDSTVMGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFA 316

Query: 938  VWIVIGFIDFGVVQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMV 997
            + +++G+                    E II       I ++    P  L LAT T  + 
Sbjct: 317  LSLLLGY-----------------GWLEAIIFL-----IGIIVANVPEGL-LATVTVCLT 353

Query: 998  GTGVA-AQNGILIKGGKPLEMAHKIKTVMFDKTGTIT 1033
             T    A+   L+K  + +E      T+  DKTGT+T
Sbjct: 354  LTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLT 390


>gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]
          Length = 1035

 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 58/219 (26%), Positives = 96/219 (43%), Gaps = 59/219 (26%)

Query: 1190 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVG-------------- 1235
            G++++ D  +     AV   ++ G+ V+++TGD+  TA+AIA  VG              
Sbjct: 598  GLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAA 657

Query: 1236 --------INK-------------------------------VFAEVLPSHKVAKVQELQ 1256
                    +N+                               VFA   P  K+  V+  Q
Sbjct: 658  RLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQ 717

Query: 1257 NKGKKVAMVGDGVNDSPALAQADMGVAIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSK 1315
              G  VA+ GDGVNDSPAL +AD+GVA+G  G+D A  AAD++L+ ++   +V  +   +
Sbjct: 718  RLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGR 777

Query: 1316 RTVRRIRINLVLALIYNLVG-----IPIAAGVFMPIGIV 1349
                 ++ ++   L  N+       I I   V +P+G +
Sbjct: 778  LIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCI 816



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 67/302 (22%), Positives = 116/302 (38%), Gaps = 44/302 (14%)

Query: 747  ILVVAVAEKAERSPVTFFDTPPMLFVFIAL---GRWLEHLAKSKTSEALAKLMSLQATEA 803
            I ++A A +A    +T  D   +    IA+        +  + K++  +A   +L   +A
Sbjct: 121  ICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQA 180

Query: 804  TVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGKVLEGN-TMADESLITGEAM 862
            TV+  G D   I  +Q+ +     GD+V++  G + P D ++L       D S +TGE+ 
Sbjct: 181  TVIRDG-DKFQINADQLVV-----GDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESE 234

Query: 863  PVTKKPGST----------VIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAP 912
            P T+ P  T              ++   G+V     + G+ T + +I  L    +  K P
Sbjct: 235  PQTRSPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENEKTP 294

Query: 913  IQQLADRFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNKHISQTEVIIRFAF 972
            I    + F        I+      +V + IG+                      +    F
Sbjct: 295  IAIEIEHFVDIIAGLAILFGATFFIVAMCIGY--------------------TFLRAMVF 334

Query: 973  QTSITVLCIACPCSLGLATPTAVMVGTGV-AAQNGILIKGGKPLEMAHKIKTVMFDKTGT 1031
              +I V  +  P  L LAT T  +  T    A    ++K  + +E       +  DKTGT
Sbjct: 335  FMAIVVAYV--PEGL-LATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGT 391

Query: 1032 IT 1033
            +T
Sbjct: 392  LT 393


>gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]
          Length = 1020

 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 58/219 (26%), Positives = 102/219 (46%), Gaps = 59/219 (26%)

Query: 1190 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI------------- 1236
            G++++ D  +     AV   +S G+ V+++TGD+  TA+AIA  VGI             
Sbjct: 584  GLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAA 643

Query: 1237 ----------------------------NKVFAEVLPSH------------KVAKVQELQ 1256
                                        ++   E+L +H            K+  V+  Q
Sbjct: 644  RLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQ 703

Query: 1257 NKGKKVAMVGDGVNDSPALAQADMGVAIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSK 1315
             +G  VA+ GDGVNDSPAL +AD+G+A+G +G+DV+ +AAD++L+ ++   +V  +   +
Sbjct: 704  RQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGR 763

Query: 1316 RTVRRIRINLVLALIYNLVGIP-----IAAGVFMPIGIV 1349
                 ++ ++   L  N+  I      I A + +P+G V
Sbjct: 764  LIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTV 802



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 60/261 (22%), Positives = 105/261 (40%), Gaps = 41/261 (15%)

Query: 785  KSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGK 844
            ++K+S+ +    ++   +A V+  GE   I  EE V       GD+V+V  G + P D +
Sbjct: 149  EAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVV------GDLVEVKGGDRVPADLR 202

Query: 845  VLEGN-TMADESLITGEAMPVTKKPGST---------VIAGSINA-HGSVLIKATHVGND 893
            ++  +    D S +TGE+ P T+ P  T         +   S N   G+        G+ 
Sbjct: 203  IISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDR 262

Query: 894  TTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQRY 953
            T + +I  L    ++ + PI    + F        + +     V+ +++G+         
Sbjct: 263  TVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGY--------- 313

Query: 954  FPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVA-AQNGILIKGG 1012
                    S  E +I       I ++    P  L LAT T  +  T    A+   L+K  
Sbjct: 314  --------SWLEAVIFL-----IGIIVANVPEGL-LATVTVCLTLTAKRMARKNCLVKNL 359

Query: 1013 KPLEMAHKIKTVMFDKTGTIT 1033
            + +E      T+  DKTGT+T
Sbjct: 360  EAVETLGSTSTICSDKTGTLT 380


>gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]
          Length = 1013

 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 58/219 (26%), Positives = 101/219 (46%), Gaps = 59/219 (26%)

Query: 1190 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI------------- 1236
            G++++ D  +     AV   +S G+ V+++TGD+  TA+AIA  VGI             
Sbjct: 577  GLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAA 636

Query: 1237 ----------------------------NKVFAEVLPSH------------KVAKVQELQ 1256
                                        ++   E+L +H            K+  V+  Q
Sbjct: 637  RLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQ 696

Query: 1257 NKGKKVAMVGDGVNDSPALAQADMGVAIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSK 1315
             +G  VA+ GDGVNDSPAL +AD+GVA+G  G+DV+ +AAD++L+ ++   +V  +   +
Sbjct: 697  RQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGR 756

Query: 1316 RTVRRIRINLVLALIYNLVGIP-----IAAGVFMPIGIV 1349
                 ++ ++   L  N+  I      I A + +P+G +
Sbjct: 757  LIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTI 795



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 58/261 (22%), Positives = 106/261 (40%), Gaps = 41/261 (15%)

Query: 785  KSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGK 844
            ++K+S+ +    ++   +A V+  GE      + QV  E V  GD+V++  G + P D +
Sbjct: 141  EAKSSKIMESFKNMVPQQALVIREGE------KMQVNAEEVVVGDLVEIKGGDRVPADLR 194

Query: 845  VLEGN-TMADESLITGEAMPVTKKPGST---------VIAGSINA-HGSVLIKATHVGND 893
            ++  +    D S +TGE+ P T+ P  T         +   S N   G+        G+ 
Sbjct: 195  IISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDR 254

Query: 894  TTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQRY 953
            T + +I  L    ++ K PI    + F        + +     ++ +++G+         
Sbjct: 255  TVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGY--------- 305

Query: 954  FPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVA-AQNGILIKGG 1012
                    +  E +I       I ++    P  L LAT T  +  T    A+   L+K  
Sbjct: 306  --------TWLEAVIFL-----IGIIVANVPEGL-LATVTVCLTLTAKRMARKNCLVKNL 351

Query: 1013 KPLEMAHKIKTVMFDKTGTIT 1033
            + +E      T+  DKTGT+T
Sbjct: 352  EAVETLGSTSTICSDKTGTLT 372


>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
            sapiens]
          Length = 1170

 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 57/192 (29%), Positives = 87/192 (45%), Gaps = 43/192 (22%)

Query: 1191 MIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI-----------NKV 1239
            ++ I D V+ E   A+   +  G+ V ++TGDN  TARAIAT+ GI            K 
Sbjct: 667  VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKE 726

Query: 1240 FAEVLPSHKVAKVQELQNK-------------------------------GKKVAMVGDG 1268
            F  ++ + K    QE  +K                                + VA+ GDG
Sbjct: 727  FNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDG 786

Query: 1269 VNDSPALAQADMGVAIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVL 1327
             ND PAL +AD+G A+G  GTDVA EA+D++L  ++   +V ++   +     I   L  
Sbjct: 787  TNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 846

Query: 1328 ALIYNLVGIPIA 1339
             L  N+V + +A
Sbjct: 847  QLTVNVVAVIVA 858



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 63/286 (22%), Positives = 107/286 (37%), Gaps = 59/286 (20%)

Query: 819  QVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTMA-DESLITGEAMPVTKK--------PG 869
            Q+P+  +  GDI +V  G   P DG +++GN +  DES +TGE+  V K          G
Sbjct: 200  QLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSG 259

Query: 870  STVIAGS---------INAHGSVLIKATHVGNDT-------------------------- 894
            + V+ GS         +N+   +++    V  D                           
Sbjct: 260  THVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGV 319

Query: 895  --------------TLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWI 940
                             +  K V+  +  K+ +Q    R +       ++MS LT+ + I
Sbjct: 320  ALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILI 379

Query: 941  VIGFIDFGVVQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTG 1000
            +   ID  V+ R    P       +  ++F F   ITVL +A P  L LA   ++     
Sbjct: 380  LYFVIDNFVINRRPWLPECTPIYIQYFVKF-FIIGITVLVVAVPEGLPLAVTISLAYSVK 438

Query: 1001 VAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLG 1046
               ++  L++     E       +  DKTGT+T     V++  + G
Sbjct: 439  KMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGG 484


>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
            sapiens]
          Length = 1205

 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 57/192 (29%), Positives = 87/192 (45%), Gaps = 43/192 (22%)

Query: 1191 MIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI-----------NKV 1239
            ++ I D V+ E   A+   +  G+ V ++TGDN  TARAIAT+ GI            K 
Sbjct: 667  VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKE 726

Query: 1240 FAEVLPSHKVAKVQELQNK-------------------------------GKKVAMVGDG 1268
            F  ++ + K    QE  +K                                + VA+ GDG
Sbjct: 727  FNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDG 786

Query: 1269 VNDSPALAQADMGVAIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVL 1327
             ND PAL +AD+G A+G  GTDVA EA+D++L  ++   +V ++   +     I   L  
Sbjct: 787  TNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 846

Query: 1328 ALIYNLVGIPIA 1339
             L  N+V + +A
Sbjct: 847  QLTVNVVAVIVA 858



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 63/286 (22%), Positives = 107/286 (37%), Gaps = 59/286 (20%)

Query: 819  QVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTMA-DESLITGEAMPVTKK--------PG 869
            Q+P+  +  GDI +V  G   P DG +++GN +  DES +TGE+  V K          G
Sbjct: 200  QLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSG 259

Query: 870  STVIAGS---------INAHGSVLIKATHVGNDT-------------------------- 894
            + V+ GS         +N+   +++    V  D                           
Sbjct: 260  THVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGV 319

Query: 895  --------------TLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWI 940
                             +  K V+  +  K+ +Q    R +       ++MS LT+ + I
Sbjct: 320  ALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILI 379

Query: 941  VIGFIDFGVVQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTG 1000
            +   ID  V+ R    P       +  ++F F   ITVL +A P  L LA   ++     
Sbjct: 380  LYFVIDNFVINRRPWLPECTPIYIQYFVKF-FIIGITVLVVAVPEGLPLAVTISLAYSVK 438

Query: 1001 VAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLG 1046
               ++  L++     E       +  DKTGT+T     V++  + G
Sbjct: 439  KMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGG 484


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.132    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,613,374
Number of Sequences: 37866
Number of extensions: 2210133
Number of successful extensions: 6407
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 6052
Number of HSP's gapped (non-prelim): 211
length of query: 1465
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1350
effective length of database: 13,892,928
effective search space: 18755452800
effective search space used: 18755452800
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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