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Search of human proteins with 5454048
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5454048 semaphorin 3C [Homo sapiens]
(751 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5454048 semaphorin 3C [Homo sapiens] 1547 0.0
gi|188497703 semaphorin 3F [Homo sapiens] 821 0.0
gi|5174673 semaphorin 3A precursor [Homo sapiens] 708 0.0
gi|41406086 semaphorin 3D [Homo sapiens] 677 0.0
gi|6912650 semaphorin 3E [Homo sapiens] 648 0.0
gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens] 640 0.0
gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens] 634 0.0
gi|9910362 semaphorin sem2 [Homo sapiens] 584 e-166
gi|214010218 semaphorin 4D isoform 1 [Homo sapiens] 348 1e-95
gi|214010220 semaphorin 4D isoform 2 [Homo sapiens] 331 2e-90
gi|39777610 semaphorin 4B precursor [Homo sapiens] 311 1e-84
gi|39777608 semaphorin 4B precursor [Homo sapiens] 311 1e-84
gi|157388902 semaphorin 4C [Homo sapiens] 300 4e-81
gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens] 290 4e-78
gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens] 288 1e-77
gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens] 288 1e-77
gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens] 288 1e-77
gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens] 284 2e-76
gi|21361914 semaphorin B [Homo sapiens] 282 7e-76
gi|28872814 semaphorin 4G [Homo sapiens] 272 1e-72
gi|11991660 sema domain, transmembrane domain (TM), and cytoplas... 272 1e-72
gi|19923279 semaphorin W [Homo sapiens] 253 5e-67
gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens] 252 8e-67
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 252 8e-67
gi|147904700 semaphorin 5A [Homo sapiens] 249 5e-66
gi|19718780 semaphorin 6B precursor [Homo sapiens] 240 3e-63
gi|16306552 semaphorin Y [Homo sapiens] 226 8e-59
gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens] 212 1e-54
gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens] 212 1e-54
gi|225637524 semaphorin 7A isoform 3 [Homo sapiens] 207 2e-53
>gi|5454048 semaphorin 3C [Homo sapiens]
Length = 751
Score = 1547 bits (4005), Expect = 0.0
Identities = 751/751 (100%), Positives = 751/751 (100%)
Query: 1 MAFRTICVLVGVFICSICVKGSSQPQARVYLTFDELRETKTSEYFSLSHHPLDYRILLMD 60
MAFRTICVLVGVFICSICVKGSSQPQARVYLTFDELRETKTSEYFSLSHHPLDYRILLMD
Sbjct: 1 MAFRTICVLVGVFICSICVKGSSQPQARVYLTFDELRETKTSEYFSLSHHPLDYRILLMD 60
Query: 61 EDQDRIYVGSKDHILSLNINNISQEALSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQ 120
EDQDRIYVGSKDHILSLNINNISQEALSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQ
Sbjct: 61 EDQDRIYVGSKDHILSLNINNISQEALSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQ 120
Query: 121 TFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMIN 180
TFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMIN
Sbjct: 121 TFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMIN 180
Query: 181 EELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKV 240
EELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKV
Sbjct: 181 EELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKV 240
Query: 241 YFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPET 300
YFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPET
Sbjct: 241 YFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPET 300
Query: 301 HFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPN 360
HFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPN
Sbjct: 301 HFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPN 360
Query: 361 HQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLI 420
HQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLI
Sbjct: 361 HQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLI 420
Query: 421 VRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVF 480
VRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVF
Sbjct: 421 VRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVF 480
Query: 481 KNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCS 540
KNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCS
Sbjct: 481 KNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCS 540
Query: 541 RFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVKNNTTFLECAPKSPQAS 600
RFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVKNNTTFLECAPKSPQAS
Sbjct: 541 RFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVKNNTTFLECAPKSPQAS 600
Query: 601 IKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFK 660
IKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFK
Sbjct: 601 IKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFK 660
Query: 661 VLDSEMVAVVTDKWSPWTWASSVRALPFHPKDIMGAFSHSEMQMINQYCKDTRQQHQQGD 720
VLDSEMVAVVTDKWSPWTWASSVRALPFHPKDIMGAFSHSEMQMINQYCKDTRQQHQQGD
Sbjct: 661 VLDSEMVAVVTDKWSPWTWASSVRALPFHPKDIMGAFSHSEMQMINQYCKDTRQQHQQGD 720
Query: 721 ESQKMRGDYGKLKALINSRKSRNRRNQLPES 751
ESQKMRGDYGKLKALINSRKSRNRRNQLPES
Sbjct: 721 ESQKMRGDYGKLKALINSRKSRNRRNQLPES 751
>gi|188497703 semaphorin 3F [Homo sapiens]
Length = 785
Score = 821 bits (2120), Expect = 0.0
Identities = 397/759 (52%), Positives = 544/759 (71%), Gaps = 39/759 (5%)
Query: 28 RVYLTFDELRETKTSEYFSLSHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEAL 87
RV L+F EL+ T T+ +F+ + DYRILL DED DR+YVGSKD++LSL++++I++E L
Sbjct: 31 RVRLSFKELKATGTAHFFNFLLNTTDYRILLKDEDHDRMYVGSKDYVLSLDLHDINREPL 90
Query: 88 SVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRR 147
+ W AS ++EEC ++GKD CGNFVR+IQ +NRTHLYVCG+GA++P+CTY+NRGRR
Sbjct: 91 IIHWAASPQRIEECVLSGKDVNGECGNFVRLIQPWNRTHLYVCGTGAYNPMCTYVNRGRR 150
Query: 148 SE-------------------------------DQVFMID-SKCESGKGRCSFNPNVNTV 175
++ D +F ++ + ESGKG+C ++P ++T
Sbjct: 151 AQATPWTQTQAVRGRGSRATDGALRPMPTAPRQDYIFYLEPERLESGKGKCPYDPKLDTA 210
Query: 176 SVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDP 235
S +INEEL++G+YIDFMGTDAAIFR+L K+ A+RTDQ+NS+WL++P F+ A +IPD +
Sbjct: 211 SALINEELYAGVYIDFMGTDAAIFRTLGKQTAMRTDQYNSRWLNDPSFIHAELIPDSAER 270
Query: 236 NDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDE 295
ND K+YFFF+E+ + +S +++ I RIC ND GG LVNKW+TFLKARLVCSV E
Sbjct: 271 NDDKLYFFFRERSAEAPQSPA-VYARIGRICLNDDGGHCCLVNKWSTFLKARLVCSVPGE 329
Query: 296 DGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAH 355
DG ETHFDEL+DVF+ +T + R ++Y +FT+S SVF+GSAVCVY ++DI+ VFNGPFAH
Sbjct: 330 DGIETHFDELQDVFVQQTQDVRNPVIYAVFTSSGSVFRGSAVCVYSMADIRMVFNGPFAH 389
Query: 356 KEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIH 415
KEGPN+Q + + G++PYPRPGTCPGG FTP+M++TK++PD+V+ F+R+HPLMY ++YP+
Sbjct: 390 KEGPNYQWMPFSGKMPYPRPGTCPGGTFTPSMKSTKDYPDEVINFMRSHPLMYQAVYPLQ 449
Query: 416 KRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSGELILE 475
+RPL+VR G Y+ T IAVD+V+AADGRY VLFLGTDRGTVQKV+VLP ++ EL+LE
Sbjct: 450 RRPLVVRTGAPYRLTTIAVDQVDAADGRYEVLFLGTDRGTVQKVIVLPKDDQELEELMLE 509
Query: 476 ELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWD 535
E+EVFK+ AP+ TM ISSK+QQLYV+S GV+ +SLHRC YG ACADCCLARDPYCAWD
Sbjct: 510 EVEVFKDPAPVKTMTISSKRQQLYVASAVGVTHLSLHRCQAYGAACADCCLARDPYCAWD 569
Query: 536 GHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVKNNTTFLECAPK 595
G +CSR+ + KRRSRRQDVRHGNP+ QCRGFN A +NA E VQYGV + FLEC P+
Sbjct: 570 GQACSRYTASSKRRSRRQDVRHGNPIRQCRGFNSNANKNAVESVQYGVAGSAAFLECQPR 629
Query: 596 SPQASIKWLLQKDK-DRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTI 654
SPQA++KWL Q+D DRR+E++ +R + T QGLL+R++Q SD+GLY C ATEN+FK +
Sbjct: 630 SPQATVKWLFQRDPGDRRREIRAEDRFLRTEQGLLLRALQLSDRGLYSCTATENNFKHVV 689
Query: 655 AKINFKVLDSEMVAVVTDKWSPWTWASSVRALPFHP--KDIMGAFSHSEMQMINQYCKDT 712
++ VL + V + A P P +++ + E+ +I+QYC+
Sbjct: 690 TRVQLHVLGRDAVHAALFPPLSMSAPPPPGAGPPTPPYQELAQLLAQPEVGLIHQYCQG- 748
Query: 713 RQQHQQGDESQKMRGDYGKLKALINSRKSRNRRNQLPES 751
+ S + + + +K RNRR+ P++
Sbjct: 749 --YWRHVPPSPREAPGAPRSPEPQDQKKPRNRRHHPPDT 785
>gi|5174673 semaphorin 3A precursor [Homo sapiens]
Length = 771
Score = 708 bits (1827), Expect = 0.0
Identities = 339/757 (44%), Positives = 508/757 (67%), Gaps = 17/757 (2%)
Query: 4 RTICVLVGVFICSIC-VKGSSQPQARVYLTFDELRETKTSEYFSLSHHPLDYRILLMDED 62
R +C+ GV + + + R+ L++ E+ E+ F+ + Y L+DE+
Sbjct: 6 RIVCLFWGVLLTARANYQNGKNNVPRLKLSYKEMLESNNVITFNGLANSSSYHTFLLDEE 65
Query: 63 QDRIYVGSKDHILSLNINNISQEALSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTF 122
+ R+YVG+KDHI S ++ NI ++ + WP S + +ECK AGKD C NF++V++ +
Sbjct: 66 RSRLYVGAKDHIFSFDLVNI-KDFQKIVWPVSYTRRDECKWAGKDILKECANFIKVLKAY 124
Query: 123 NRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMID-SKCESGKGRCSFNPNVNTVSVMINE 181
N+THLY CG+GAF P+CTY+ G ED +F ++ S E+G+G+ ++P + T S++I+
Sbjct: 125 NQTHLYACGTGAFHPICTYIEIGHHPEDNIFKLENSHFENGRGKSPYDPKLLTASLLIDG 184
Query: 182 ELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVY 241
EL+SG DFMG D AIFR+L + +RT+QH+S+WL++P F+ AH+I + +P D KVY
Sbjct: 185 ELYSGTAADFMGRDFAIFRTLGHHHPIRTEQHDSRWLNDPKFISAHLISESDNPEDDKVY 244
Query: 242 FFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETH 301
FFF+E D S K H+ I +IC ND GG RSLVNKWTTFLKARL+CSV +G +TH
Sbjct: 245 FFFRENAIDGEHSGKATHARIGQICKNDFGGHRSLVNKWTTFLKARLICSVPGPNGIDTH 304
Query: 302 FDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNH 361
FDEL+DVFL+ +P+ +VYG+FTTSS++FKGSAVC+Y +SD++ VF GP+AH++GPN+
Sbjct: 305 FDELQDVFLMNFKDPKNPVVYGVFTTSSNIFKGSAVCMYSMSDVRRVFLGPYAHRDGPNY 364
Query: 362 QLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIV 421
Q + YQGR+PYPRPGTCP F +TK+ PDDV+TF R+HP MYN ++P++ RP+++
Sbjct: 365 QWVPYQGRVPYPRPGTCPSKTF-GGFDSTKDLPDDVITFARSHPAMYNPVFPMNNRPIVI 423
Query: 422 RIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVS-GELILEELEVF 480
+ +Y++T+I VDRV+A DG+Y V+F+GTD GTV KVV +P E++LEE+ VF
Sbjct: 424 KTDVNYQFTQIVVDRVDAEDGQYDVMFIGTDVGTVLKVVSIPKETWYDLEEVLLEEMTVF 483
Query: 481 KNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCS 540
+ I+ M++S+K+QQLY+ S GV+Q+ LHRC IYG ACA+CCLARDPYCAWDG +CS
Sbjct: 484 REPTAISAMELSTKQQQLYIGSTAGVAQLPLHRCDIYGKACAECCLARDPYCAWDGSACS 543
Query: 541 RFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAY--RNAAEIVQYGVKNNTTFLECAPKSPQ 598
R++PT KRR+RRQD+R+G+PLT C + + + E + YGV+N++TFLEC+PKS +
Sbjct: 544 RYFPTAKRRTRRQDIRNGDPLTHCSDLHHDNHHGHSPEERIIYGVENSSTFLECSPKSQR 603
Query: 599 ASIKWLLQ-KDKDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKI 657
A + W Q ++++R++E+++++ II T QGLL+RS+Q D G Y C A E+ F QT+ K+
Sbjct: 604 ALVYWQFQRRNEERKEEIRVDDHIIRTDQGLLLRSLQQKDSGNYLCHAVEHGFIQTLLKV 663
Query: 658 NFKVLDSEMVAVVTDKWSPWTWA-------SSVRALPFHPKDIMGAFSHSEMQMINQYCK 710
+V+D+E + + K + S + +D M +H + ++++C+
Sbjct: 664 TLEVIDTEHLEELLHKDDDGDGSKTKEMSNSMTPSQKVWYRDFMQLINHPNLNTMDEFCE 723
Query: 711 DT--RQQHQQGDESQKMRGDYGKLKALINSRKSRNRR 745
R + Q+ G+ K K L ++K RNRR
Sbjct: 724 QVWKRDRKQRRQRPGHTPGNSNKWKHLQENKKGRNRR 760
>gi|41406086 semaphorin 3D [Homo sapiens]
Length = 777
Score = 677 bits (1746), Expect = 0.0
Identities = 337/726 (46%), Positives = 483/726 (66%), Gaps = 12/726 (1%)
Query: 28 RVYLTFDELRETKTSEYFSLSHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEAL 87
R+ LT+ +L + + F S LD++ LL+DE++ R+ +G+KDHI L++ ++++
Sbjct: 44 RLKLTYKDLLLSNSCIPFLGSSEGLDFQTLLLDEERGRLLLGAKDHIFLLSLVDLNKNFK 103
Query: 88 SVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRR 147
++WPA+ +VE CK+AGKD C NF+RV+Q +N+TH+YVCG+GAF P+C Y++ G
Sbjct: 104 KIYWPAAKERVELCKLAGKDANTECANFIRVLQPYNKTHIYVCGTGAFHPICGYIDLGVY 163
Query: 148 SEDQVFMIDS-KCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTK-- 204
ED +F +D+ ESG+ +C F+P SVM +E L+SG DF+G D A RSL
Sbjct: 164 KEDIIFKLDTHNLESGRLKCPFDPQQPFASVMTDEYLYSGTASDFLGKDTAFTRSLGPTH 223
Query: 205 -RNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIA 263
+ +RTD WL+ F+ IPD +P+D K+YFFF+E + + S K I S +
Sbjct: 224 DHHYIRTDISEHYWLNGAKFIGTFFIPDTYNPDDDKIYFFFRESSQEGSTSDKTILSRVG 283
Query: 264 RICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYG 323
R+C ND GG RSL+NKWTTFLKARL+CS+ DG +T+FDEL+D++LL T + R +VYG
Sbjct: 284 RVCKNDVGGQRSLINKWTTFLKARLICSIPGSDGADTYFDELQDIYLLPTRDERNPVVYG 343
Query: 324 IFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAF 383
+FTT+SS+FKGSAVCVY ++DI+ VFNGP+AHKE +H+ + Y GRIPYPRPGTCP +
Sbjct: 344 VFTTTSSIFKGSAVCVYSMADIRAVFNGPYAHKESADHRWVQYDGRIPYPRPGTCPSKTY 403
Query: 384 TPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGR 443
P +++T++FPDDV++FI+ H +MY S+YP+ P RI DY+ T+I VD V A DG+
Sbjct: 404 DPLIKSTRDFPDDVISFIKRHSVMYKSVYPVAGGPTFKRINVDYRLTQIVVDHVIAEDGQ 463
Query: 444 YHVLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVFKNHAPITTMKISSKKQQLYVSSN 503
Y V+FLGTD GTV KVV + E++LEEL++FK+ + I M++S K+QQLY+ S
Sbjct: 464 YDVMFLGTDIGTVLKVVSISKEKWNMEEVVLEELQIFKHSSIILNMELSLKQQQLYIGSR 523
Query: 504 EGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQ 563
+G+ Q+SLHRC YG ACADCCLARDPYCAWDG++CSR+ PT KRR+RRQDV++G+P+TQ
Sbjct: 524 DGLVQLSLHRCDTYGKACADCCLARDPYCAWDGNACSRYAPTSKRRARRQDVKYGDPITQ 583
Query: 564 CRGF-NLKAYRNAAEIVQYGVKNNTTFLECAPKSPQASIKWLLQKDKD-RRKEVKLNERI 621
C + ++ A E V +G++ N+TFLEC PKS QA+IKW +Q+ D R+E+K +ERI
Sbjct: 584 CWDIEDSISHETADEKVIFGIEFNSTFLECIPKSQQATIKWYIQRSGDEHREELKPDERI 643
Query: 622 IATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFKVLDSE-MVAVVTDKWSPWTWA 680
I T GLLIRS+Q D G+Y+C A E++F TI K+ V+++E M +
Sbjct: 644 IKTEYGLLIRSLQKKDSGMYYCKAQEHTFIHTIVKLTLNVIENEQMENTQRAEHEEGKVK 703
Query: 681 SSVRALPFHPKDIMGAFSHSEMQMINQYCKDTRQQHQQGDESQKMRGDYGKLKALINSRK 740
+ KD + S ++QYC+ Q + Q+ +G K K + +K
Sbjct: 704 DLLAESRLRYKDYIQILSSPNFS-LDQYCE---QMWHREKRRQRNKGG-PKWKHMQEMKK 758
Query: 741 SRNRRN 746
RNRR+
Sbjct: 759 KRNRRH 764
>gi|6912650 semaphorin 3E [Homo sapiens]
Length = 775
Score = 648 bits (1671), Expect = 0.0
Identities = 322/701 (45%), Positives = 453/701 (64%), Gaps = 20/701 (2%)
Query: 28 RVYLTFDELRETKTSEYFSLSHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEAL 87
R+ L+ EL + F LD +L+DE Q+R++VG +D + SL++ IS
Sbjct: 32 RLRLSHKELLNLNRTSIFHSPFGFLDLHTMLLDEYQERLFVGGRDLVYSLSLERISDGYK 91
Query: 88 SVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRR 147
+ WP++ +K+EEC M GKD C N+VRV+ +NRTHL CG+GAF PVC ++ G
Sbjct: 92 EIHWPSTALKMEECIMKGKDAGE-CANYVRVLHHYNRTHLLTCGTGAFDPVCAFIRVGYH 150
Query: 148 SEDQVFMIDS-KCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRN 206
ED +F ++S + E G+GRC F+P+ + +S +I ELF+G+Y D+ DAAIFRS+ +
Sbjct: 151 LEDPLFHLESPRSERGRGRCPFDPSSSFISTLIGSELFAGLYSDYWSRDAAIFRSMGRLA 210
Query: 207 AVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARIC 266
+RT+ + + L EP FV +++IPD D +D KVYFFF EK + + I++ + R+C
Sbjct: 211 HIRTEHDDERLLKEPKFVGSYMIPDNEDRDDNKVYFFFTEKALEAENNAHAIYTRVGRLC 270
Query: 267 PNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFT 326
ND GG R LVNKW+TFLKARLVCSV +G +T+FDELEDVFLL T + + +++G+F
Sbjct: 271 VNDVGGQRILVNKWSTFLKARLVCSVPGMNGIDTYFDELEDVFLLPTRDHKNPVIFGLFN 330
Query: 327 TSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPN 386
T+S++F+G A+CVYH+S I+ FNGP+AHKEGP + Y+G++PYPRPG+C
Sbjct: 331 TTSNIFRGHAICVYHMSSIRAAFNGPYAHKEGPEYHWSVYEGKVPYPRPGSCASKVNGGR 390
Query: 387 MRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHV 446
TTK++PDD + F R+HPLMY +I P HK+P++V+ Y +IAVDRV A DG+Y V
Sbjct: 391 YGTTKDYPDDAIRFARSHPLMYQAIKPAHKKPILVKTDGKYNLKQIAVDRVEAEDGQYDV 450
Query: 447 LFLGTDRGTVQKVVVLPTNNSVS-GELILEELEVFKNHAPITTMKISSKKQQLYVSSNEG 505
LF+GTD G V KV+ + S E+ILEEL++FK+ PI +M+ISSK+QQLY+ S
Sbjct: 451 LFIGTDNGIVLKVITIYNQEMESMEEVILEELQIFKDPVPIISMEISSKRQQLYIGSASA 510
Query: 506 VSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTG---KRRSRRQDVRHGNPLT 562
V+QV H C +YG+ACADCCLARDPYCAWDG SCSR+YPTG KRR RRQDVRHGN
Sbjct: 511 VAQVRFHHCDMYGSACADCCLARDPYCAWDGISCSRYYPTGTHAKRRFRRQDVRHGNAAQ 570
Query: 563 QCRG--FNLKAYRNAAEIVQYGVKNNTTFLECAPKSPQASIKWLLQKDKDRRK-EVKLNE 619
QC G F A E + YG++NN+T LEC P+S QA + W +QK ++ RK EVK ++
Sbjct: 571 QCFGQQFVGDALDKTEEHLAYGIENNSTLLECTPRSLQAKVIWFVQKGRETRKEEVKTDD 630
Query: 620 RIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDKWS---- 675
R++ GLL + SD G Y C E+SF T+ KI +V++ E V + +K
Sbjct: 631 RVVKMDLGLLFLRLHKSDAGTYFCQTVEHSFVHTVRKITLEVVEEEKVEDMFNKDDEEDR 690
Query: 676 ------PWTWASSVRALPFHPKDIMGAFSHSEMQMINQYCK 710
P + S A P++ K+ + +S Q + +YC+
Sbjct: 691 HHRMPCPAQSSISQGAKPWY-KEFLQLIGYSNFQRVEEYCE 730
>gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens]
Length = 749
Score = 640 bits (1651), Expect = 0.0
Identities = 318/649 (48%), Positives = 444/649 (68%), Gaps = 10/649 (1%)
Query: 21 GSSQPQA-RVYLTFDELRETKTSEYFSLSHHPLDYRILLMDEDQDRIYVGSKDHILSLNI 79
GS+ P R+ L+F EL+ + FSL Y+ LL+DE++ R++VG+++H+ SLN+
Sbjct: 22 GSAAPSPPRLRLSFQELQAWHGLQTFSLER-TCCYQALLVDEERGRLFVGAENHVASLNL 80
Query: 80 NNISQEALSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVC 139
+NIS+ A + WPA EEC AGKD C NFV+++ +NRTHL CG+GAF P C
Sbjct: 81 DNISKRAKKLAWPAPVEWREECNWAGKDIGTECMNFVKLLHAYNRTHLLACGTGAFHPTC 140
Query: 140 TYLNRGRRSEDQVFMID-SKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAI 198
++ G R+E+ V +D + E GKG+ ++P SV++ EEL+SG+ D MG D I
Sbjct: 141 AFVEVGHRAEEPVLRLDPGRIEDGKGKSPYDPRHRAASVLVGEELYSGVAADLMGRDFTI 200
Query: 199 FRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQI 258
FRSL +R ++RT+ H+S+WL+EP FV IP+ +P+D K+YFFF+E + + ++
Sbjct: 201 FRSLGQRPSLRTEPHDSRWLNEPKFVKVFWIPESENPDDDKIYFFFRETAVEAAPALGRL 260
Query: 259 H-SMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPR 317
S + +IC ND GG RSLVNKWTTFLKARLVCSV +G +THFD+L+DVFLL + + R
Sbjct: 261 SVSRVGQICRNDVGGQRSLVNKWTTFLKARLVCSVPGVEG-DTHFDQLQDVFLLSSRDHR 319
Query: 318 TTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGT 377
T L+Y +F+TSSS+F+GSAVCVY ++D++ F GPFAHKEGP HQ +SYQGR+PYPRPG
Sbjct: 320 TPLLYAVFSTSSSIFQGSAVCVYSMNDVRRAFLGPFAHKEGPMHQWVSYQGRVPYPRPGM 379
Query: 378 CPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRV 437
CP F +TK+FPDDV+ F RNHPLMYNS+ P RPL +++G +Y +T+IA DRV
Sbjct: 380 CPSKTFG-TFSSTKDFPDDVIQFARNHPLMYNSVLPTGGRPLFLQVGANYTFTQIAADRV 438
Query: 438 NAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSGE-LILEELEVFKNHAPITTMKISSKKQ 496
AADG Y VLF+GTD GTV KV+ +P + S E L+LEEL VF++ A +T+M+ISSK+
Sbjct: 439 AAADGHYDVLFIGTDVGTVLKVISVPKGSRPSAEGLLLEELHVFEDSAAVTSMQISSKRH 498
Query: 497 QLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVR 556
QLYV+S V+Q++LHRC +G C +CCLARDPYCAWDG +C+RF P+ KRR RRQDVR
Sbjct: 499 QLYVASRSAVAQIALHRCAAHGRVCTECCLARDPYCAWDGVACTRFQPSAKRRFRRQDVR 558
Query: 557 HGNPLTQCRGFNLKAYRNAAEIVQYGVKNNTTFLECAPKSPQASIKWLLQK-DKDRRKEV 615
+G+P T C G + + E +GV+ ++ FLEC P+S QA ++W Q+ +V
Sbjct: 559 NGDPSTLCSGDSSRP--ALLEHKVFGVEGSSAFLECEPRSLQARVEWTFQRAGVTAHTQV 616
Query: 616 KLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFKVLDS 664
ER T++GLL+R ++ D G+Y C A E F Q + +++ VL +
Sbjct: 617 LAEERTERTARGLLLRRLRRRDSGVYLCAAVEQGFTQPLRRLSLHVLSA 665
>gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens]
Length = 748
Score = 634 bits (1635), Expect = 0.0
Identities = 317/649 (48%), Positives = 443/649 (68%), Gaps = 11/649 (1%)
Query: 21 GSSQPQA-RVYLTFDELRETKTSEYFSLSHHPLDYRILLMDEDQDRIYVGSKDHILSLNI 79
GS+ P R+ L+F EL+ + FSL Y+ LL+DE++ R++VG+++H+ SLN+
Sbjct: 22 GSAAPSPPRLRLSFQELQAWHGLQTFSLER-TCCYQALLVDEERGRLFVGAENHVASLNL 80
Query: 80 NNISQEALSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVC 139
+NIS+ A + WPA EEC AGKD C NFV+++ +NRTHL CG+GAF P C
Sbjct: 81 DNISKRAKKLAWPAPVEWREECNWAGKDIGTECMNFVKLLHAYNRTHLLACGTGAFHPTC 140
Query: 140 TYLNRGRRSEDQVFMID-SKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAI 198
++ G R+E+ V +D + E GKG+ ++P SV++ EEL+SG+ D MG D I
Sbjct: 141 AFVEVGHRAEEPVLRLDPGRIEDGKGKSPYDPRHRAASVLVGEELYSGVAADLMGRDFTI 200
Query: 199 FRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQI 258
FRSL +R ++RT+ H+S+WL+EP FV IP+ +P+D K+YFFF+E + + ++
Sbjct: 201 FRSLGQRPSLRTEPHDSRWLNEPKFVKVFWIPESENPDDDKIYFFFRETAVEAAPALGRL 260
Query: 259 H-SMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPR 317
S + +IC ND GG RSLVNKWTTFLKARLVCSV +G +THFD+L+DVFLL + + R
Sbjct: 261 SVSRVGQICRNDVGGQRSLVNKWTTFLKARLVCSVPGVEG-DTHFDQLQDVFLLSSRDHR 319
Query: 318 TTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGT 377
T L+Y +F+TSS +F+GSAVCVY ++D++ F GPFAHKEGP HQ +SYQGR+PYPRPG
Sbjct: 320 TPLLYAVFSTSS-IFQGSAVCVYSMNDVRRAFLGPFAHKEGPMHQWVSYQGRVPYPRPGM 378
Query: 378 CPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRV 437
CP F +TK+FPDDV+ F RNHPLMYNS+ P RPL +++G +Y +T+IA DRV
Sbjct: 379 CPSKTFG-TFSSTKDFPDDVIQFARNHPLMYNSVLPTGGRPLFLQVGANYTFTQIAADRV 437
Query: 438 NAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSGE-LILEELEVFKNHAPITTMKISSKKQ 496
AADG Y VLF+GTD GTV KV+ +P + S E L+LEEL VF++ A +T+M+ISSK+
Sbjct: 438 AAADGHYDVLFIGTDVGTVLKVISVPKGSRPSAEGLLLEELHVFEDSAAVTSMQISSKRH 497
Query: 497 QLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVR 556
QLYV+S V+Q++LHRC +G C +CCLARDPYCAWDG +C+RF P+ KRR RRQDVR
Sbjct: 498 QLYVASRSAVAQIALHRCAAHGRVCTECCLARDPYCAWDGVACTRFQPSAKRRFRRQDVR 557
Query: 557 HGNPLTQCRGFNLKAYRNAAEIVQYGVKNNTTFLECAPKSPQASIKWLLQK-DKDRRKEV 615
+G+P T C G + + E +GV+ ++ FLEC P+S QA ++W Q+ +V
Sbjct: 558 NGDPSTLCSGDSSRP--ALLEHKVFGVEGSSAFLECEPRSLQARVEWTFQRAGVTAHTQV 615
Query: 616 KLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFKVLDS 664
ER T++GLL+R ++ D G+Y C A E F Q + +++ VL +
Sbjct: 616 LAEERTERTARGLLLRRLRRRDSGVYLCAAVEQGFTQPLRRLSLHVLSA 664
>gi|9910362 semaphorin sem2 [Homo sapiens]
Length = 782
Score = 584 bits (1505), Expect = e-166
Identities = 308/671 (45%), Positives = 418/671 (62%), Gaps = 18/671 (2%)
Query: 6 ICVLVGVFICSICVKGSSQPQA-----RVYLTFDELRETKTSEYFSLSHHPLDYRILLMD 60
IC L+G + GSS P R+ L++ +L S F L+ + + +D
Sbjct: 8 ICWLLGGLLLH---GGSSGPSPGPSVPRLRLSYRDLLSANRSAIFLGPQGSLNLQAMYLD 64
Query: 61 EDQDRIYVGSKDHILSLNINNISQEALSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQ 120
E +DR+++G D + SL ++ + V WP + EEC G+DP C NFVRV+Q
Sbjct: 65 EYRDRLFLGGLDALYSLRLDQAWPDPREVLWPPQPGQREECVRKGRDPLTECANFVRVLQ 124
Query: 121 TFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMIN 180
NRTHL CG+GAF P C + G R E + + ESG+GRC P+ S I+
Sbjct: 125 PHNRTHLLACGTGAFQPTCALITVGHRGEHVLHLEPGSVESGRGRCPHEPSRPFASTFID 184
Query: 181 EELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKV 240
EL++G+ DF+G +A IFRS R A+R+D S L +P FV A IP+ +D ++ KV
Sbjct: 185 GELYTGLTADFLGREAMIFRSGGPRPALRSDSDQSL-LHDPRFVMAARIPENSDQDNDKV 243
Query: 241 YFFFKEKLTDNNRSTKQIH-SMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPE 299
YFFF E + + + + S + R+C ND GG R LVNKW+TFLKARLVCSV G E
Sbjct: 244 YFFFSETVPSPDGGSNHVTVSRVGRVCVNDAGGQRVLVNKWSTFLKARLVCSVPGPGGAE 303
Query: 300 THFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGP 359
THFD+LEDVFLL ++ VY +F+T S+VF+G AVCVYH++DI VFNGPFAH++GP
Sbjct: 304 THFDQLEDVFLLWPKAGKSLEVYALFSTVSAVFQGFAVCVYHMADIWEVFNGPFAHRDGP 363
Query: 360 NHQLISYQGRIPYPRPGTCPGGAFTPNMR---TTKEFPDDVVTFIRNHPLMYNSIYPIHK 416
HQ Y G++P+PRPG CP R +TK++PD+V+ F R HPLM+ + P H
Sbjct: 364 QHQWGPYGGKVPFPRPGVCPSKMTAQPGRPFGSTKDYPDEVLQFARAHPLMFWPVRPRHG 423
Query: 417 RPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVS-GELILE 475
RP++V+ + +I VDRV A DG Y V+FLGTD G+V KV+ L S E++LE
Sbjct: 424 RPVLVKTHLAQQLHQIVVDRVEAEDGTYDVIFLGTDSGSVLKVIALQAGGSAEPEEVVLE 483
Query: 476 ELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWD 535
EL+VFK PIT M+IS K+Q LYV S GV+Q+ LH+C YGTACA+CCLARDPYCAWD
Sbjct: 484 ELQVFKVPTPITEMEISVKRQMLYVGSRLGVAQLRLHQCETYGTACAECCLARDPYCAWD 543
Query: 536 GHSCSRFYPT-GKRRSRRQDVRHGNPLTQCRGFNL--KAYRNAAEIVQYGVKNNTTFLEC 592
G SC+ + P+ GKRR RRQD+RHGNP QC G + +A A + YG ++N+TFLEC
Sbjct: 544 GASCTHYRPSLGKRRFRRQDIRHGNPALQCLGQSQEEEAVGLVAATMVYGTEHNSTFLEC 603
Query: 593 APKSPQASIKWLLQKDKDR-RKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFK 651
PKSPQA+++WLLQ+ D +VK +ER++ T +GLL R + D G Y C E+ F
Sbjct: 604 LPKSPQAAVRWLLQRPGDEGPDQVKTDERVLHTERGLLFRRLSRFDAGTYTCTTLEHGFS 663
Query: 652 QTIAKINFKVL 662
QT+ ++ V+
Sbjct: 664 QTVVRLALVVI 674
>gi|214010218 semaphorin 4D isoform 1 [Homo sapiens]
Length = 862
Score = 348 bits (892), Expect = 1e-95
Identities = 225/635 (35%), Positives = 340/635 (53%), Gaps = 44/635 (6%)
Query: 49 HHP--LDYRILLMDEDQDRIYVGSKDHILSLNINNISQEALSVFWPASTIKVEECKMAGK 106
H P +Y LL+ ED+D +Y+G+++ + ++N NIS++ V+W S K +C GK
Sbjct: 43 HEPDIYNYSALLLSEDKDTLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGK 102
Query: 107 DPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRC 166
C N++RV+Q + T LYVCG+ AF P C +LN F K E GKGRC
Sbjct: 103 SKQTECLNYIRVLQPLSATSLYVCGTNAFQPACDHLNL------TSFKFLGKNEDGKGRC 156
Query: 167 SFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDA 226
F+P + SVM++ EL+SG +F+G++ I R+ + + +RT ++ WL+EP FV A
Sbjct: 157 PFDPAHSYTSVMVDGELYSGTSYNFLGSEPIISRN-SSHSPLRT-EYAIPWLNEPSFVFA 214
Query: 227 HVI---PDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTF 283
VI PD D D +VYFFF E + + + IAR+C D GGLR+L KWT+F
Sbjct: 215 DVIRKSPDSPDGEDDRVYFFFTEVSVEYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSF 274
Query: 284 LKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLS 343
LKARL+CS D F+ L DVF+L + + + Y +FT + SAVC Y+LS
Sbjct: 275 LKARLICSRPDSG---LVFNVLRDVFVLRSPGLKVPVFYALFTPQLNNVGLSAVCAYNLS 331
Query: 344 DIQTVF-NGPFAHK---EGPNHQLISYQGRIPYPRPGTC-PGGAFTPNMRTTKEFPDDVV 398
+ VF +G + E + + + Y G +P PRPG C A N ++ PD +
Sbjct: 332 TAEEVFSHGKYMQSTTVEQSHTKWVRYNGPVPKPRPGACIDSEARAANYTSSLNLPDKTL 391
Query: 399 TFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGR-YHVLFLGTDRGTVQ 457
F+++HPLM +S+ PI RP +++ D YT+I VDR A DG Y V+F+ TDRG +
Sbjct: 392 QFVKDHPLMDDSVTPIDNRPRLIK--KDVNYTQIVVDRTQALDGTVYDVMFVSTDRGALH 449
Query: 458 KVVVLPTNNSVSGELILEELEVFKNHAPITTMKISSKK--QQLYVSSNEGVSQVSLHRCH 515
K + L ++V I+EE ++F++ P+ T+ +SSKK + +Y SN GV Q L C
Sbjct: 450 KAISL--EHAVH---IIEETQLFQDFEPVQTLLLSSKKGNRFVYAGSNSGVVQAPLAFCG 504
Query: 516 IYGTACADCCLARDPYCAWD--GHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYR 573
+GT C DC LARDPYCAW +C + T + SR + C + +YR
Sbjct: 505 KHGT-CEDCVLARDPYCAWSPPTATCVALHQT-ESPSRGLIQEMSGDASVCPDKSKGSYR 562
Query: 574 NAAEIVQYGVKNNTTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSV 633
+ T L+C+ KS A + W Q + + K + + LLI ++
Sbjct: 563 Q-----HFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPKYG---LMGRKNLLIFNL 614
Query: 634 QGSDQGLYHCIATENSFKQTIAKINFK-VLDSEMV 667
D G+Y C++ E +T+ ++ K VL+ ++V
Sbjct: 615 SEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVV 649
>gi|214010220 semaphorin 4D isoform 2 [Homo sapiens]
Length = 738
Score = 331 bits (848), Expect = 2e-90
Identities = 196/499 (39%), Positives = 285/499 (57%), Gaps = 32/499 (6%)
Query: 49 HHP--LDYRILLMDEDQDRIYVGSKDHILSLNINNISQEALSVFWPASTIKVEECKMAGK 106
H P +Y LL+ ED+D +Y+G+++ + ++N NIS++ V+W S K +C GK
Sbjct: 43 HEPDIYNYSALLLSEDKDTLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGK 102
Query: 107 DPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRC 166
C N++RV+Q + T LYVCG+ AF P C +LN F K E GKGRC
Sbjct: 103 SKQTECLNYIRVLQPLSATSLYVCGTNAFQPACDHLNL------TSFKFLGKNEDGKGRC 156
Query: 167 SFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDA 226
F+P + SVM++ EL+SG +F+G++ I R+ + + +RT ++ WL+EP FV A
Sbjct: 157 PFDPAHSYTSVMVDGELYSGTSYNFLGSEPIISRN-SSHSPLRT-EYAIPWLNEPSFVFA 214
Query: 227 HVI---PDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTF 283
VI PD D D +VYFFF E + + + IAR+C D GGLR+L KWT+F
Sbjct: 215 DVIRKSPDSPDGEDDRVYFFFTEVSVEYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSF 274
Query: 284 LKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLS 343
LKARL+CS D F+ L DVF+L + + + Y +FT + SAVC Y+LS
Sbjct: 275 LKARLICSRPDSG---LVFNVLRDVFVLRSPGLKVPVFYALFTPQLNNVGLSAVCAYNLS 331
Query: 344 DIQTVF-NGPFAHK---EGPNHQLISYQGRIPYPRPGTC-PGGAFTPNMRTTKEFPDDVV 398
+ VF +G + E + + + Y G +P PRPG C A N ++ PD +
Sbjct: 332 TAEEVFSHGKYMQSTTVEQSHTKWVRYNGPVPKPRPGACIDSEARAANYTSSLNLPDKTL 391
Query: 399 TFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGR-YHVLFLGTDRGTVQ 457
F+++HPLM +S+ PI RP +++ D YT+I VDR A DG Y V+F+ TDRG +
Sbjct: 392 QFVKDHPLMDDSVTPIDNRPRLIK--KDVNYTQIVVDRTQALDGTVYDVMFVSTDRGALH 449
Query: 458 KVVVLPTNNSVSGELILEELEVFKNHAPITTMKISSKK--QQLYVSSNEGVSQVSLHRCH 515
K + L ++V I+EE ++F++ P+ T+ +SSKK + +Y SN GV Q L C
Sbjct: 450 KAISL--EHAVH---IIEETQLFQDFEPVQTLLLSSKKGNRFVYAGSNSGVVQAPLAFCG 504
Query: 516 IYGTACADCCLARDPYCAW 534
+GT C DC LARDPYCAW
Sbjct: 505 KHGT-CEDCVLARDPYCAW 522
>gi|39777610 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 311 bits (798), Expect = 1e-84
Identities = 215/656 (32%), Positives = 328/656 (50%), Gaps = 64/656 (9%)
Query: 48 SHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNIS----QEALSVFWPASTIKVEECKM 103
+ H +Y LL+ D +YVG+++ + +L+ +N+S E + W A K ++C
Sbjct: 64 AEHISNYTALLLSRDGRTLYVGAREALFALS-SNLSFLPGGEYQELLWGADAEKKQQCSF 122
Query: 104 AGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSK----C 159
GKDP C N+++++ + +HL+ CG+ AFSP+CTY+N E+ D K
Sbjct: 123 KGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYIN----MENFTLARDEKGNVLL 178
Query: 160 ESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLS 219
E GKGRC F+PN + +++++ EL++G F G D AI RS + R N WL
Sbjct: 179 EDGKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPTKTESSLN--WLQ 236
Query: 220 EPMFVDAHVIPD---GTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSL 276
+P FV + IP+ +D K+YFFF E + I S IARIC D GG R L
Sbjct: 237 DPAFVASAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVL 296
Query: 277 VNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLL--ETDNPRTTLVYGIFTTS--SSVF 332
+WT+FLKA+L+CS D+ P F+ L+DVF L + R TL YG+FT+
Sbjct: 297 QQRWTSFLKAQLLCSRPDDGFP---FNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTT 353
Query: 333 KGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTC-PGGAFTPNMRTTK 391
+GSAVCV+ + D+Q VF+G + Q + +P PRPG C A + ++
Sbjct: 354 EGSAVCVFTMKDVQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSL 413
Query: 392 EFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGT 451
+ PD V+ F+++H LM + R ++ + +Y ++AV RV Y VLFLGT
Sbjct: 414 QLPDRVLNFLKDHFLMDGQV-----RSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGT 468
Query: 452 DRGTVQKVVVLPTNNSVSGEL-ILEELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVS 510
G + K V SV + I+EEL++F + P+ + + + + LY +S+ GV QV
Sbjct: 469 GDGRLHKAV------SVGPRVHIIEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVP 522
Query: 511 LHRCHIYGTACADCCLARDPYCAWDGHSC---SRFYPTGKRRSRRQDVRHGNPLTQCRGF 567
+ C +Y +C DC LARDPYCAW G SC S + P R QD+ + C
Sbjct: 523 MANCSLY-RSCGDCLLARDPYCAWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSAS 581
Query: 568 N------LKAYRNAAEIVQYGVKNNTTFLECAPKSPQASIKWLLQKDKDRRKEVKLNE-- 619
+ + E VQ+ N L C S A+ WL R +N
Sbjct: 582 SVVSPSFVPTGEKPCEQVQF-QPNTVNTLACPLLSNLATRLWL-------RNGAPVNASA 633
Query: 620 --RIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDK 673
++ T LL+ + Q G + C + E F+Q +A +V++ + VA TD+
Sbjct: 634 SCHVLPTGDLLLVGTQQ---LGEFQCWSLEEGFQQLVASYCPEVVE-DGVADQTDE 685
>gi|39777608 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 311 bits (798), Expect = 1e-84
Identities = 215/656 (32%), Positives = 328/656 (50%), Gaps = 64/656 (9%)
Query: 48 SHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNIS----QEALSVFWPASTIKVEECKM 103
+ H +Y LL+ D +YVG+++ + +L+ +N+S E + W A K ++C
Sbjct: 64 AEHISNYTALLLSRDGRTLYVGAREALFALS-SNLSFLPGGEYQELLWGADAEKKQQCSF 122
Query: 104 AGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSK----C 159
GKDP C N+++++ + +HL+ CG+ AFSP+CTY+N E+ D K
Sbjct: 123 KGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYIN----MENFTLARDEKGNVLL 178
Query: 160 ESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLS 219
E GKGRC F+PN + +++++ EL++G F G D AI RS + R N WL
Sbjct: 179 EDGKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPTKTESSLN--WLQ 236
Query: 220 EPMFVDAHVIPD---GTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSL 276
+P FV + IP+ +D K+YFFF E + I S IARIC D GG R L
Sbjct: 237 DPAFVASAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVL 296
Query: 277 VNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLL--ETDNPRTTLVYGIFTTS--SSVF 332
+WT+FLKA+L+CS D+ P F+ L+DVF L + R TL YG+FT+
Sbjct: 297 QQRWTSFLKAQLLCSRPDDGFP---FNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTT 353
Query: 333 KGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTC-PGGAFTPNMRTTK 391
+GSAVCV+ + D+Q VF+G + Q + +P PRPG C A + ++
Sbjct: 354 EGSAVCVFTMKDVQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSL 413
Query: 392 EFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGT 451
+ PD V+ F+++H LM + R ++ + +Y ++AV RV Y VLFLGT
Sbjct: 414 QLPDRVLNFLKDHFLMDGQV-----RSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGT 468
Query: 452 DRGTVQKVVVLPTNNSVSGEL-ILEELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVS 510
G + K V SV + I+EEL++F + P+ + + + + LY +S+ GV QV
Sbjct: 469 GDGRLHKAV------SVGPRVHIIEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVP 522
Query: 511 LHRCHIYGTACADCCLARDPYCAWDGHSC---SRFYPTGKRRSRRQDVRHGNPLTQCRGF 567
+ C +Y +C DC LARDPYCAW G SC S + P R QD+ + C
Sbjct: 523 MANCSLY-RSCGDCLLARDPYCAWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSAS 581
Query: 568 N------LKAYRNAAEIVQYGVKNNTTFLECAPKSPQASIKWLLQKDKDRRKEVKLNE-- 619
+ + E VQ+ N L C S A+ WL R +N
Sbjct: 582 SVVSPSFVPTGEKPCEQVQF-QPNTVNTLACPLLSNLATRLWL-------RNGAPVNASA 633
Query: 620 --RIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDK 673
++ T LL+ + Q G + C + E F+Q +A +V++ + VA TD+
Sbjct: 634 SCHVLPTGDLLLVGTQQ---LGEFQCWSLEEGFQQLVASYCPEVVE-DGVADQTDE 685
>gi|157388902 semaphorin 4C [Homo sapiens]
Length = 833
Score = 300 bits (767), Expect = 4e-81
Identities = 190/603 (31%), Positives = 309/603 (51%), Gaps = 31/603 (5%)
Query: 53 DYRILLMDEDQDRIYVGSKDHILSLNINNISQEALSVFWPASTIKVEECKMAGKDPTHGC 112
D+ L + E +YVG+++ + + ++ + + ++ W A K EC GK+ C
Sbjct: 52 DFLTLTLTEPTGLLYVGAREALFAFSMEALELQG-AISWEAPVEKKTECIQKGKNNQTEC 110
Query: 113 GNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMID-SKCESGKGRCSFNPN 171
NF+R +Q +N +HLYVCG+ AF P CTY+N F ++ + E GKG+C ++P
Sbjct: 111 FNFIRFLQPYNASHLYVCGTYAFQPKCTYVNM------LTFTLEHGEFEDGKGKCPYDPA 164
Query: 172 VNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPD 231
++++ EL+S +F+GT+ I R++ ++++T+ + + WL+EP FV + +P+
Sbjct: 165 KGHAGLLVDGELYSATLNNFLGTEPIILRNMGPHHSMKTE-YLAFWLNEPHFVGSAYVPE 223
Query: 232 GTDP---NDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARL 288
+D KVYFFF+E+ +++ +Q+ + +AR+C D GG R+L KWTTFLKARL
Sbjct: 224 SVGSFTGDDDKVYFFFRERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARL 283
Query: 289 VCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTV 348
CS + + +F++L+ + L+ + T +G+F SA+C Y L +IQ V
Sbjct: 284 ACSAPNW---QLYFNQLQAMHTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRV 340
Query: 349 FNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTK-EFPDDVVTFIRNHPLM 407
F GP+ + Y +P PRPG+C + T+ E PD+++ F++ HPLM
Sbjct: 341 FEGPYKEYHEEAQKWDRYTDPVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLM 400
Query: 408 YNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADG-RYHVLFLGTDRGTVQKVVVLPTNN 466
+ P RPL+V+ GT+ +T + DRV DG Y VLF+GT G + K V L
Sbjct: 401 EEQVGPRWSRPLLVKKGTN--FTHLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLG--- 455
Query: 467 SVSGELILEELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCL 526
++EEL++F + P+ ++ +S K+ L+ S + Q+ + C Y +CADC L
Sbjct: 456 --PWVHLIEELQLF-DQEPMRSLVLSQSKKLLFAGSRSQLVQLPVADCMKY-RSCADCVL 511
Query: 527 ARDPYCAWDGHSCSRFYPTGKRRSRR--QDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVK 584
ARDPYCAW ++ SR G Q V + C K R + + V
Sbjct: 512 ARDPYCAWSVNT-SRCVAVGGHSGSLLIQHVMTSDTSGICNLRGSKKVRPTPKNITV-VA 569
Query: 585 NNTTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCI 644
L C S A +W +D E + A Q L++ + Q G YHC
Sbjct: 570 GTDLVLPCHLSSNLAHARWTF-GGRDLPAEQPGSFLYDARLQALVVMAAQPRHAGAYHCF 628
Query: 645 ATE 647
+ E
Sbjct: 629 SEE 631
>gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]
Length = 998
Score = 290 bits (741), Expect = 4e-78
Identities = 174/538 (32%), Positives = 283/538 (52%), Gaps = 39/538 (7%)
Query: 48 SHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEAL----SVFWPASTIKVEECKM 103
S H LD++++L + +D +Y+ +D + ++N+N + + + + W + E C M
Sbjct: 53 SQHRLDFQLML--KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAM 110
Query: 104 AGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGK 163
GK C NF++V N ++VCG+ AF+P+C Y D + SG
Sbjct: 111 KGKHKDE-CHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLS------TLEYDGEEISGL 163
Query: 164 GRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMF 223
RC F+ V++ + +L+S DF+ +DA I+RS+ +A+RT +++SKW+ EP F
Sbjct: 164 ARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHF 223
Query: 224 VDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNK-WTT 282
+ H I G VYFFF+E ++N K ++S +ARIC ND GG + ++ K WT+
Sbjct: 224 L--HAIEYGN-----YVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTS 276
Query: 283 FLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHL 342
FLKARL CSV + +FD L+ + + N T+V G+FTT + GSAVC + +
Sbjct: 277 FLKARLNCSVPGDSF--FYFDVLQSITDIIQINGIPTVV-GVFTTQLNSIPGSAVCAFSM 333
Query: 343 SDIQTVFNGPFAHKEGPNHQLISY-QGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFI 401
DI+ VF G F ++ P+ + + ++P PRPG C +T+ +FPD+ ++FI
Sbjct: 334 DDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFI 393
Query: 402 RNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVV 461
++HPLM +++ PI P + Y+ T I+VD Y V+F+G++ G V KV+
Sbjct: 394 KSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLA 453
Query: 462 LPTNNSVSGELILEELEVFKNHA----------PITTMKISSKKQQLYVSSNEGVSQVSL 511
+ S++ ++LEE+E + NHA + ++++ LYV+ + + ++ L
Sbjct: 454 KTSPFSLNDSVLLEEIEAY-NHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPL 512
Query: 512 HRCHIYGTACADCCLARDPYCAW-DGHSCSRFYPTGKRRSRRQDVRHGNP--LTQCRG 566
RC YG+ C +RDPYC W SC R P QD GN L C G
Sbjct: 513 SRCERYGSCKKSCIASRDPYCGWLSQGSCGRVTPGMLAEGYEQDTEFGNTAHLGDCHG 570
>gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens]
Length = 597
Score = 288 bits (738), Expect = 1e-77
Identities = 171/529 (32%), Positives = 280/529 (52%), Gaps = 37/529 (6%)
Query: 48 SHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEAL----SVFWPASTIKVEECKM 103
S H LD++++L + +D +Y+ +D + ++N+N + + + + W + E C M
Sbjct: 53 SQHRLDFQLML--KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAM 110
Query: 104 AGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGK 163
GK C NF++V N ++VCG+ AF+P+C Y D + SG
Sbjct: 111 KGKHKDE-CHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLS------TLEYDGEEISGL 163
Query: 164 GRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMF 223
RC F+ V++ + +L+S DF+ +DA I+RS+ +A+RT +++SKW+ EP F
Sbjct: 164 ARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHF 223
Query: 224 VDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNK-WTT 282
+ H I G VYFFF+E ++N K ++S +ARIC ND GG + ++ K WT+
Sbjct: 224 L--HAIEYGN-----YVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTS 276
Query: 283 FLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHL 342
FLKARL CSV + +FD L+ + + N T+V G+FTT + GSAVC + +
Sbjct: 277 FLKARLNCSVPGDSF--FYFDVLQSITDIIQINGIPTVV-GVFTTQLNSIPGSAVCAFSM 333
Query: 343 SDIQTVFNGPFAHKEGPNHQLISY-QGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFI 401
DI+ VF G F ++ P+ + + ++P PRPG C +T+ +FPD+ ++FI
Sbjct: 334 DDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFI 393
Query: 402 RNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVV 461
++HPLM +++ PI P + Y+ T I+VD Y V+F+G++ G V KV+
Sbjct: 394 KSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLA 453
Query: 462 LPTNNSVSGELILEELEVFKNHA----------PITTMKISSKKQQLYVSSNEGVSQVSL 511
+ S++ ++LEE+E + NHA + ++++ LYV+ + + ++ L
Sbjct: 454 KTSPFSLNDSVLLEEIEAY-NHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPL 512
Query: 512 HRCHIYGTACADCCLARDPYCAW-DGHSCSRFYPTGKRRSRRQDVRHGN 559
RC YG+ C +RDPYC W SC R P QD GN
Sbjct: 513 SRCERYGSCKKSCIASRDPYCGWLSQGSCGRVTPGMLAEGYEQDTEFGN 561
>gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]
Length = 1073
Score = 288 bits (738), Expect = 1e-77
Identities = 171/529 (32%), Positives = 280/529 (52%), Gaps = 37/529 (6%)
Query: 48 SHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEAL----SVFWPASTIKVEECKM 103
S H LD++++L + +D +Y+ +D + ++N+N + + + + W + E C M
Sbjct: 53 SQHRLDFQLML--KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAM 110
Query: 104 AGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGK 163
GK C NF++V N ++VCG+ AF+P+C Y D + SG
Sbjct: 111 KGKHKDE-CHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLS------TLEYDGEEISGL 163
Query: 164 GRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMF 223
RC F+ V++ + +L+S DF+ +DA I+RS+ +A+RT +++SKW+ EP F
Sbjct: 164 ARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHF 223
Query: 224 VDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNK-WTT 282
+ H I G VYFFF+E ++N K ++S +ARIC ND GG + ++ K WT+
Sbjct: 224 L--HAIEYGN-----YVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTS 276
Query: 283 FLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHL 342
FLKARL CSV + +FD L+ + + N T+V G+FTT + GSAVC + +
Sbjct: 277 FLKARLNCSVPGDSF--FYFDVLQSITDIIQINGIPTVV-GVFTTQLNSIPGSAVCAFSM 333
Query: 343 SDIQTVFNGPFAHKEGPNHQLISY-QGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFI 401
DI+ VF G F ++ P+ + + ++P PRPG C +T+ +FPD+ ++FI
Sbjct: 334 DDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFI 393
Query: 402 RNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVV 461
++HPLM +++ PI P + Y+ T I+VD Y V+F+G++ G V KV+
Sbjct: 394 KSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLA 453
Query: 462 LPTNNSVSGELILEELEVFKNHA----------PITTMKISSKKQQLYVSSNEGVSQVSL 511
+ S++ ++LEE+E + NHA + ++++ LYV+ + + ++ L
Sbjct: 454 KTSPFSLNDSVLLEEIEAY-NHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPL 512
Query: 512 HRCHIYGTACADCCLARDPYCAW-DGHSCSRFYPTGKRRSRRQDVRHGN 559
RC YG+ C +RDPYC W SC R P QD GN
Sbjct: 513 SRCERYGSCKKSCIASRDPYCGWLSQGSCGRVTPGMLAEGYEQDTEFGN 561
>gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]
Length = 1017
Score = 288 bits (738), Expect = 1e-77
Identities = 171/529 (32%), Positives = 280/529 (52%), Gaps = 37/529 (6%)
Query: 48 SHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEAL----SVFWPASTIKVEECKM 103
S H LD++++L + +D +Y+ +D + ++N+N + + + + W + E C M
Sbjct: 53 SQHRLDFQLML--KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAM 110
Query: 104 AGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGK 163
GK C NF++V N ++VCG+ AF+P+C Y D + SG
Sbjct: 111 KGKHKDE-CHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLS------TLEYDGEEISGL 163
Query: 164 GRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMF 223
RC F+ V++ + +L+S DF+ +DA I+RS+ +A+RT +++SKW+ EP F
Sbjct: 164 ARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHF 223
Query: 224 VDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNK-WTT 282
+ H I G VYFFF+E ++N K ++S +ARIC ND GG + ++ K WT+
Sbjct: 224 L--HAIEYGN-----YVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTS 276
Query: 283 FLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHL 342
FLKARL CSV + +FD L+ + + N T+V G+FTT + GSAVC + +
Sbjct: 277 FLKARLNCSVPGDSF--FYFDVLQSITDIIQINGIPTVV-GVFTTQLNSIPGSAVCAFSM 333
Query: 343 SDIQTVFNGPFAHKEGPNHQLISY-QGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFI 401
DI+ VF G F ++ P+ + + ++P PRPG C +T+ +FPD+ ++FI
Sbjct: 334 DDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFI 393
Query: 402 RNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVV 461
++HPLM +++ PI P + Y+ T I+VD Y V+F+G++ G V KV+
Sbjct: 394 KSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLA 453
Query: 462 LPTNNSVSGELILEELEVFKNHA----------PITTMKISSKKQQLYVSSNEGVSQVSL 511
+ S++ ++LEE+E + NHA + ++++ LYV+ + + ++ L
Sbjct: 454 KTSPFSLNDSVLLEEIEAY-NHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPL 512
Query: 512 HRCHIYGTACADCCLARDPYCAW-DGHSCSRFYPTGKRRSRRQDVRHGN 559
RC YG+ C +RDPYC W SC R P QD GN
Sbjct: 513 SRCERYGSCKKSCIASRDPYCGWLSQGSCGRVTPGMLAEGYEQDTEFGN 561
>gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]
Length = 1011
Score = 284 bits (726), Expect = 2e-76
Identities = 167/514 (32%), Positives = 276/514 (53%), Gaps = 37/514 (7%)
Query: 48 SHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEAL----SVFWPASTIKVEECKM 103
S H LD++++L + +D +Y+ +D + ++N+N + + + + W + E C M
Sbjct: 53 SQHRLDFQLML--KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAM 110
Query: 104 AGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGK 163
GK C NF++V N ++VCG+ AF+P+C Y D + SG
Sbjct: 111 KGKHKDE-CHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLS------TLEYDGEEISGL 163
Query: 164 GRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMF 223
RC F+ V++ + +L+S DF+ +DA I+RS+ +A+RT +++SKW+ EP F
Sbjct: 164 ARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHF 223
Query: 224 VDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNK-WTT 282
+ H I G VYFFF+E ++N K ++S +ARIC ND GG + ++ K WT+
Sbjct: 224 L--HAIEYGN-----YVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTS 276
Query: 283 FLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHL 342
FLKARL CSV + +FD L+ + + N T+V G+FTT + GSAVC + +
Sbjct: 277 FLKARLNCSVPGDSF--FYFDVLQSITDIIQINGIPTVV-GVFTTQLNSIPGSAVCAFSM 333
Query: 343 SDIQTVFNGPFAHKEGPNHQLISY-QGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFI 401
DI+ VF G F ++ P+ + + ++P PRPG C +T+ +FPD+ ++FI
Sbjct: 334 DDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFI 393
Query: 402 RNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVV 461
++HPLM +++ PI P + Y+ T I+VD Y V+F+G++ G V KV+
Sbjct: 394 KSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLA 453
Query: 462 LPTNNSVSGELILEELEVFKNHA----------PITTMKISSKKQQLYVSSNEGVSQVSL 511
+ S++ ++LEE+E + NHA + ++++ LYV+ + + ++ L
Sbjct: 454 KTSPFSLNDSVLLEEIEAY-NHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPL 512
Query: 512 HRCHIYGTACADCCLARDPYCAW-DGHSCSRFYP 544
RC YG+ C +RDPYC W SC R P
Sbjct: 513 SRCERYGSCKKSCIASRDPYCGWLSQGSCGRVTP 546
>gi|21361914 semaphorin B [Homo sapiens]
Length = 761
Score = 282 bits (722), Expect = 7e-76
Identities = 201/648 (31%), Positives = 316/648 (48%), Gaps = 60/648 (9%)
Query: 21 GSSQPQARV-YLTFDELRETKTSEYFSLSHHPLDYRILLMDEDQDRIYVGSKDHILSLNI 79
G P RV Y DE R L D+ LL+ D + +YVG+++ IL+L+I
Sbjct: 34 GGQGPMPRVRYYAGDERRALSFFHQKGLQ----DFDTLLLSGDGNTLYVGAREAILALDI 89
Query: 80 NNISQEALS--VFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSP 137
+ L + WPAS K EC K C NF+RV+ ++N THLY CG+ AFSP
Sbjct: 90 QDPGVPRLKNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSP 149
Query: 138 VCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAA 197
CT++ + + + + K GKG+ F+P +V+++ L+SG +F+G++
Sbjct: 150 ACTFIE--LQDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGTMNNFLGSEPI 207
Query: 198 IFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQ 257
+ R+L + ++TD +WL DA + P+ VYFFF+E ++ + +
Sbjct: 208 LMRTLGSQPVLKTDNF-LRWLHH----DASFV--AAIPSTQVVYFFFEETASEFDFFERL 260
Query: 258 IHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPR 317
S +AR+C ND GG + L KWTTFLKA+L+C+ + F+ + LL D+P
Sbjct: 261 HTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCT----QPGQLPFNVIRHAVLLPADSPT 316
Query: 318 TTLVYGIFTTSSSV--FKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRP 375
+Y +FT+ V + SAVC + L DI+ VF G + + +Y+G PRP
Sbjct: 317 APHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRP 376
Query: 376 GTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVD 435
G+C G + D +TF+++H LM + PL+V+ G + YT++AV+
Sbjct: 377 GSCSVGPSS----------DKALTFMKDHFLMDEQVV---GTPLLVKSGVE--YTRLAVE 421
Query: 436 RVNAADGRYH-VLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVFKNHAPITTMKISSK 494
DG H V++LGT G++ K VV + S ++EE+++F + P+ ++++
Sbjct: 422 TAQGLDGHSHLVMYLGTTTGSLHKAVV----SGDSSAHLVEEIQLFPDPEPVRNLQLAPT 477
Query: 495 KQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHS---CSRFYPTGKRRSR 551
+ ++V + GV +V C +Y +C DC LARDP+CAWD S C P S
Sbjct: 478 QGAVFVGFSGGVWRVPRANCSVY-ESCVDCVLARDPHCAWDPESRTCCLLSAP--NLNSW 534
Query: 552 RQDVRHGNPLTQCRGFNLKAY---RNAAEIVQ--YGVKNNTTFLECAPKSPQASIKWLLQ 606
+QD+ GNP C + ++ +I++ V N+ L C S AS W
Sbjct: 535 KQDMERGNPEWACASGPMSRSLRPQSRPQIIKEVLAVPNSILELPCPHLSALASYYW--- 591
Query: 607 KDKDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTI 654
+ E G L+ VQ GLY C ATEN F +
Sbjct: 592 ----SHGPAAVPEASSTVYNGSLLLIVQDGVGGLYQCWATENGFSYPV 635
>gi|28872814 semaphorin 4G [Homo sapiens]
Length = 843
Score = 272 bits (695), Expect = 1e-72
Identities = 194/661 (29%), Positives = 313/661 (47%), Gaps = 67/661 (10%)
Query: 28 RVYLTFDELRETKTSEYFSLSHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEA- 86
R+ + ++EL T+ +Y LL++E R+ VG++ + SL+ N+I A
Sbjct: 35 RMTIPYEELSGTR-----HFKGQAQNYSTLLLEEASARLLVGARGALFSLSANDIGDGAH 89
Query: 87 LSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGR 146
+ W AS +C GK+ C N VR +Q N THLY CG+ AF P+C +
Sbjct: 90 KEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYACGTHAFQPLCAAI---- 145
Query: 147 RSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRN 206
+ + F + + E GK +C ++P ++I+ L++ +F R +
Sbjct: 146 --DAEAFTLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPD--IRRSRHPH 201
Query: 207 AVRTDQHNSKWLSEPMFVDAHVIPDGTDP---NDAKVYFFFKEKLTD-------NNRSTK 256
++RT++ WL++ FV + ++ + +D KVY+FF E+ T+ +RS+
Sbjct: 202 SLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSH 261
Query: 257 QIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNP 316
++ + +AR+C D GG + L KWT+FLKARL+C + ++ L V L+ +
Sbjct: 262 RV-ARVARVCKGDLGGKKILQKKWTSFLKARLICHI-------PLYETLRGVCSLDAETS 313
Query: 317 RTTLVYGIFTTSS--SVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPR 374
T Y FT S+ + SA+C Y L++IQ VF GP+ + + + Y+G +P PR
Sbjct: 314 SRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSRRWGRYEGGVPEPR 373
Query: 375 PGTCPGGAF-TPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIA 433
PG+C + + ++++ P V+ F++ HPLM + P RPL+++ + +YT +
Sbjct: 374 PGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLK--RNIRYTHLT 431
Query: 434 VDRVNAADG-RYHVLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVFKNHAPITTMKIS 492
V G Y +LFLGT G + K VVL SG I+EE +VF+ + + IS
Sbjct: 432 GTPVTTPAGPTYDLLFLGTADGWIHKAVVLG-----SGMHIIEETQVFRESQSVENLVIS 486
Query: 493 SKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWD--GHSCSRF-----YPT 545
+ LYV + GV Q+ L C Y +C DC LARDPYC WD H+C+
Sbjct: 487 LLQHSLYVGAPSGVIQLPLSSCSRY-RSCYDCILARDPYCGWDPGTHACAAATTIANRSQ 545
Query: 546 GKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYG--VKNNTTFLECAPKSPQASIKW 603
G R + QD+ GN RG ++ ++ + L C S A W
Sbjct: 546 GSRTALIQDIERGN-----RGCESSRDTGPPPPLKTRSVLRGDDVLLPCDQPSNLARALW 600
Query: 604 LLQKD---KDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFK 660
LL D + ++ GLL+ Q G Y C A EN + +A +
Sbjct: 601 LLNGSMGLSDGQGGYRVG------VDGLLVTDAQPEHSGNYGCYAEENGLRTLLASYSLT 654
Query: 661 V 661
V
Sbjct: 655 V 655
>gi|11991660 sema domain, transmembrane domain (TM), and cytoplasmic
domain, (semaphorin) 6A [Homo sapiens]
Length = 1030
Score = 272 bits (695), Expect = 1e-72
Identities = 174/528 (32%), Positives = 269/528 (50%), Gaps = 38/528 (7%)
Query: 50 HPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEAL----SVFWPASTIKVEECKMAG 105
H LD +++++ +Y+ ++DHI +++I+ E + + W + V+ C+M G
Sbjct: 54 HRLDIQMIMIMNGT--LYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKG 111
Query: 106 KDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGR 165
K C NF++V+ N L+VCG+ AF+P C R + SG R
Sbjct: 112 KHKDE-CHNFIKVLLKKNDDALFVCGTNAFNPSC------RNYKMDTLEPFGDEFSGMAR 164
Query: 166 CSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVD 225
C ++ V++ + +L+S DF+ DA I+RSL + +RT +H+SKWL EP FV
Sbjct: 165 CPYDAKHANVALFADGKLYSATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQ 224
Query: 226 AHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNK-WTTFL 284
A D D +YFFF+E + N K + +A++C ND GG + ++ K WT+FL
Sbjct: 225 A------VDYGDY-IYFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFL 277
Query: 285 KARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSD 344
KARL CSV + +F+ L+ V + N R +V F+T + GSAVC Y + D
Sbjct: 278 KARLNCSVPGDS--HFYFNILQAVTDVIRINGRD-VVLATFSTPYNSIPGSAVCAYDMLD 334
Query: 345 IQTVFNGPFAHKEGPNHQLISYQG-RIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRN 403
I +VF G F ++ P+ R+P PRPG C G + T+ EFPDD + FI+
Sbjct: 335 IASVFTGRFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSLERYATSNEFPDDTLNFIKT 394
Query: 404 HPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLP 463
HPLM ++ I RP +R Y+ TKIAVD + V+FLG+++G + K +
Sbjct: 395 HPLMDEAVPSIFNRPWFLRTMVRYRLTKIAVDTAAGPYQNHTVVFLGSEKGIILKFLARI 454
Query: 464 TNNS-VSGELILEELEVFKNH---------APITTMKISSKKQQLYVSSNEGVSQVSLHR 513
N+ ++ L LEE+ V+ + I M++ LYV+ + V +V L R
Sbjct: 455 GNSGFLNDSLFLEEMSVYNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGR 514
Query: 514 CHIYGTACADCCLARDPYCAW--DGHSCSRFYPTGKRRSRRQDVRHGN 559
C +G C +RDPYC W +G +CS P R + QD+ GN
Sbjct: 515 CERHGKCKKTCIASRDPYCGWIKEGGACSHLSP-NSRLTFEQDIERGN 561
>gi|19923279 semaphorin W [Homo sapiens]
Length = 770
Score = 253 bits (646), Expect = 5e-67
Identities = 181/569 (31%), Positives = 273/569 (47%), Gaps = 46/569 (8%)
Query: 50 HPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEALSVFWPASTIKVEECKMAGKDPT 109
H +Y +LL+D +YVG++D I +L++ + + W + C+ GK
Sbjct: 61 HTYNYSVLLVDPASHTLYVGARDTIFALSLPFSGERPRRIDWMVPEAHRQNCRKKGKKED 120
Query: 110 HGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFN 169
C NFV+++ N +HL CG+ AF P C ++ R F + ESG+G+C F
Sbjct: 121 E-CHNFVQILAIANASHLLTCGTFAFDPKCGVIDVSR------FQQVERLESGRGKCPFE 173
Query: 170 PNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTK-RNAVRTDQHNSKWLSEPMFVDAHV 228
P + +VM L++ +++GT+ I R++ + + +RTD S WL+ P FV A
Sbjct: 174 PAQRSAAVMAGGVLYAATVKNYLGTEPIITRAVGRAEDWIRTDTLPS-WLNAPAFVAAVA 232
Query: 229 IPD---GTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLK 285
+ G + D ++YFFF E + + +AR+C D GG ++L +WTTFLK
Sbjct: 233 LSPAEWGDEDGDDEIYFFFTETSRAFDSYERIKVPRVARVCAGDLGGRKTLQQRWTTFLK 292
Query: 286 ARLVCSVTDEDGPE--THFDELEDVFLLETD-NPRTTLVYGIFTTSSSVFKGSAVCVYHL 342
A L+C GPE L+DV +L + T + YGIF++ SAVC +
Sbjct: 293 ADLLC-----PGPEHGRASSVLQDVAVLRPELGAGTPIFYGIFSSQWEGATISAVCAFRP 347
Query: 343 SDIQTVFNGPFAH-KEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMR-----TTKEFPDD 396
DI+TV NGPF K N L +P PRPG C T NM+ ++ PD
Sbjct: 348 QDIRTVLNGPFRELKHDCNRGLPVVDNDVPQPRPGEC----ITNNMKLRHFGSSLSLPDR 403
Query: 397 VVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGR-YHVLFLGTDRGT 455
V+TFIR+HPLM ++P PL+V TD Y ++ RV + G+ Y VL+LGT+ G
Sbjct: 404 VLTFIRDHPLMDRPVFPADGHPLLVT--TDTAYLRVVAHRVTSLSGKEYDVLYLGTEDGH 461
Query: 456 VQKVVVLPTNNSVSGELILEELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCH 515
+ + V + SV LE+L +F P+ MK+ L V S V+QV+ C
Sbjct: 462 LHRAVRIGAQLSV-----LEDLALFPEPQPVENMKL--YHSWLLVGSRTEVTQVNTTNCG 514
Query: 516 IYGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNA 575
+C++C LA+DP CAW G+ R QD+ + + C K
Sbjct: 515 RL-QSCSECILAQDPVCAWSFRLDECVAHAGEHRGLVQDIESADVSSLCP----KEPGER 569
Query: 576 AEIVQYGVKNNT-TFLECAPKSPQASIKW 603
+ + V L C+P S AS W
Sbjct: 570 PVVFEVPVATAAHVVLPCSPSSAWASCVW 598
>gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens]
Length = 476
Score = 252 bits (644), Expect = 8e-67
Identities = 148/443 (33%), Positives = 245/443 (55%), Gaps = 26/443 (5%)
Query: 48 SHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEAL----SVFWPASTIKVEECKM 103
S H LD++++L + +D +Y+ +D + ++N+N + + + + W + E C M
Sbjct: 53 SQHRLDFQLML--KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAM 110
Query: 104 AGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGK 163
GK C NF++V N ++VCG+ AF+P+C Y D + SG
Sbjct: 111 KGKHKDE-CHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLS------TLEYDGEEISGL 163
Query: 164 GRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMF 223
RC F+ V++ + +L+S DF+ +DA I+RS+ +A+RT +++SKW+ EP F
Sbjct: 164 ARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHF 223
Query: 224 VDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNK-WTT 282
+ H I G VYFFF+E ++N K ++S +ARIC ND GG + ++ K WT+
Sbjct: 224 L--HAIEYGN-----YVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTS 276
Query: 283 FLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHL 342
FLKARL CSV + +FD L+ + + N T+V G+FTT + GSAVC + +
Sbjct: 277 FLKARLNCSVPGDSF--FYFDVLQSITDIIQINGIPTVV-GVFTTQLNSIPGSAVCAFSM 333
Query: 343 SDIQTVFNGPFAHKEGPNHQLISY-QGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFI 401
DI+ VF G F ++ P+ + + ++P PRPG C +T+ +FPD+ ++FI
Sbjct: 334 DDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFI 393
Query: 402 RNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVV 461
++HPLM +++ PI P + Y+ T I+VD Y V+F+G++ G V KV+
Sbjct: 394 KSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLA 453
Query: 462 LPTNNSVSGELILEELEVFKNHA 484
+ S++ ++LEE+E + NHA
Sbjct: 454 KTSPFSLNDSVLLEEIEAY-NHA 475
>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
Length = 1151
Score = 252 bits (644), Expect = 8e-67
Identities = 166/487 (34%), Positives = 254/487 (52%), Gaps = 37/487 (7%)
Query: 53 DYRILLMDEDQDRIYVGSKDHILSLNINNISQEALSVFWPASTIKVEECKMAGKDPTHGC 112
D+ L +D +++ VG+++++ L++ N+S + W +S C+ GK C
Sbjct: 125 DFSQLALDPSGNQLIVGARNYLFRLSLANVSL-LQATEWASSEDTRRSCQSKGKTEEE-C 182
Query: 113 GNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNV 172
N+VRV+ R +++CG+ AFSP+CT G S + +G RC ++P
Sbjct: 183 QNYVRVLIVAGRK-VFMCGTNAFSPMCTSRQVGNLSRTIEKI------NGVARCPYDPRH 235
Query: 173 NTVSVMINE-ELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPD 231
N+ +V+ ++ EL++ IDF G D AI+RSL +RT Q+NSKWL+EP FV A+ I
Sbjct: 236 NSTAVISSQGELYAATVIDFSGRDPAIYRSLGSGPPLRTAQYNSKWLNEPNFVAAYDI-- 293
Query: 232 GTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCS 291
YFF +E +++ + ++S +AR+C ND GG L + WTTF+KARL CS
Sbjct: 294 -----GLFAYFFLRENAVEHDCG-RTVYSRVARVCKNDVGGRFLLEDTWTTFMKARLNCS 347
Query: 292 VTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNG 351
E +++EL+ F L P L+YG+FTT+ + SAVC ++LS I FNG
Sbjct: 348 RPGE--VPFYYNELQSAFHL----PEQDLIYGVFTTNVNSIAASAVCAFNLSAISQAFNG 401
Query: 352 PFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSI 411
PF ++E P + IP + GT P PN T+ D LM ++
Sbjct: 402 PFRYQENPRAAWLPIANPIPNFQCGTLPETG--PNENLTERSLQDAQRLF----LMSEAV 455
Query: 412 YPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSGE 471
P+ P + + +++ + VD V A D YHVL++GT+ GT+ K L T +
Sbjct: 456 QPVTPEPCVTQ--DSVRFSHLVVDLVQAKDTLYHVLYIGTESGTILK--ALSTASRSLHG 511
Query: 472 LILEELEVFK--NHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARD 529
LEEL V P+ +++I + L+V +GV +V L RC Y + A C ARD
Sbjct: 512 CYLEELHVLPPGRREPLRSLRILHSARALFVGLRDGVLRVPLERCAAYRSQGA-CLGARD 570
Query: 530 PYCAWDG 536
PYC WDG
Sbjct: 571 PYCGWDG 577
>gi|147904700 semaphorin 5A [Homo sapiens]
Length = 1074
Score = 249 bits (637), Expect = 5e-66
Identities = 164/489 (33%), Positives = 256/489 (52%), Gaps = 42/489 (8%)
Query: 52 LDYRILLMDEDQDRIYVGSKDHILSLNINNISQEALSVFWPASTIKVEECKMAGKDPTHG 111
+D+ L D Q + VG+++++ L + ++S +V W + C GK
Sbjct: 56 VDFSQLTFDPGQKELVVGARNYLFRLQLEDLSL-IQAVEWECDEATKKACYSKGKSKEE- 113
Query: 112 CGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSE--DQVFMIDSKCESGKGRCSFN 169
C N++RV+ L+ CG+ AF+PVCT + +E DQ+ SG RC ++
Sbjct: 114 CQNYIRVLLV-GGDRLFTCGTNAFTPVCTNRSLSNLTEIHDQI--------SGMARCPYS 164
Query: 170 PNVNTVSVMI-NEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHV 228
P N+ +++ EL++ +DF G D AI+RSL +RT Q+NSKWL+EP FV ++
Sbjct: 165 PQHNSTALLTAGGELYAATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYD 224
Query: 229 IPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARL 288
I + T YFFF+E +++ K + S AR+C ND GG L + WTTF+KARL
Sbjct: 225 IGNFT-------YFFFRENAVEHDCG-KTVFSRAARVCKNDIGGRFLLEDTWTTFMKARL 276
Query: 289 VCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTV 348
CS E +++EL+ F L P L+YGIFTT+ + SAVCV++LS I
Sbjct: 277 NCSRPGE--VPFYYNELQSTFFL----PELDLIYGIFTTNVNSIAASAVCVFNLSAIAQA 330
Query: 349 FNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMY 408
F+GPF ++E + Y P+ + GT G + + T+ D FI LM+
Sbjct: 331 FSGPFKYQENSRSAWLPYPNPNPHFQCGTVDQGLY---VNLTERNLQDAQKFI----LMH 383
Query: 409 NSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSV 468
+ P+ P + + +++ +AVD V + H+++L TD GT++KV V N
Sbjct: 384 EVVQPVTTVPSFME--DNSRFSHVAVDVVQGREALVHIIYLATDYGTIKKVRV--PLNQT 439
Query: 469 SGELILEELEVF--KNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCL 526
S +LEE+E+F + PI +++I + L+V E V ++ L RC Y T + C
Sbjct: 440 SSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREHVVKIPLKRCQFYRTR-STCIG 498
Query: 527 ARDPYCAWD 535
A+DPYC WD
Sbjct: 499 AQDPYCGWD 507
>gi|19718780 semaphorin 6B precursor [Homo sapiens]
Length = 888
Score = 240 bits (613), Expect = 3e-63
Identities = 179/598 (29%), Positives = 284/598 (47%), Gaps = 53/598 (8%)
Query: 66 IYVGSKDHILSLNINNISQEAL----SVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQT 121
+++G +D++ + + + L + W ++ + C+M GK C NFV+V+
Sbjct: 77 LFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQEGE-CRNFVKVLLL 135
Query: 122 FNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINE 181
+ + L+VCGS AF+PVC S D + + SG RC ++P V++ +
Sbjct: 136 RDESTLFVCGSNAFNPVCA-----NYSIDTLQPVGDNI-SGMARCPYDPKHANVALFSDG 189
Query: 182 ELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVY 241
LF+ DF+ DA I+RSL R +RT +H+SKW EP FV H + G + VY
Sbjct: 190 MLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFV--HAVEWG-----SHVY 242
Query: 242 FFFKEKLTDNNRSTKQIHSMIARICPNDTGGL-RSLVNKWTTFLKARLVCSVTDEDGPET 300
FFF+E + N K + S +AR+C ND GG R L +WT+FLKARL CSV +
Sbjct: 243 FFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDS--HF 300
Query: 301 HFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPN 360
+F+ L+ V + + R +V +F+T S+ GSAVC + L+ + VF G F ++ P
Sbjct: 301 YFNVLQAVTGVVSLGGR-PVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPE 359
Query: 361 HQLISY-QGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPL 419
+ ++P PRPG C N + PDD++ F++ HPLM ++ + P
Sbjct: 360 SIWTPVPEDQVPRPRPGCCAAPGMQYN--ASSALPDDILNFVKTHPLMDEAVPSLGHAPW 417
Query: 420 IVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSG----ELILE 475
I+R ++ T++AVD G V+FLG++ GTV K +V P N S SG + LE
Sbjct: 418 ILRTLMRHQLTRVAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRP-NASTSGTSGLSVFLE 476
Query: 476 ELEVFK-----------NHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADC 524
E E ++ + ++++ + L + V +V + RC Y +C
Sbjct: 477 EFETYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNC 536
Query: 525 CLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNP--LTQCRGF---NLKAYRNAAEIV 579
++DPYC W F G R + QDV + L C G +L R V
Sbjct: 537 IGSQDPYCGWAPDGSCIFLSPGTRAAFEQDVSGASTSGLGDCTGLLRASLSEDRAGLVSV 596
Query: 580 QYGVKNNTTFLECAPKSPQASIKWLL----QKDKDRRKEVKLNERIIATSQGLLIRSV 633
V ++ S+ W + +++ RRK+ E I+A G + SV
Sbjct: 597 NLLVTSSVAAFVVGAVVSGFSVGWFVGLRERRELARRKD---KEAILAHGAGEAVLSV 651
>gi|16306552 semaphorin Y [Homo sapiens]
Length = 930
Score = 226 bits (575), Expect = 8e-59
Identities = 148/485 (30%), Positives = 253/485 (52%), Gaps = 34/485 (7%)
Query: 66 IYVGSKDHILSLNINNISQ-EAL--SVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTF 122
+ V ++DH+ S ++ + E L + + + VE C + GK T C N++RV+ +
Sbjct: 73 LLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRSQDVENCAVRGK-LTDECYNYIRVLVPW 131
Query: 123 NRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEE 182
+ L CG+ +FSPVC + G S Q + + SG+ RC F+ + V++
Sbjct: 132 DSQTLLACGTNSFSPVCR--SYGITSLQQ----EGEELSGQARCPFDATQSNVAIFAEGS 185
Query: 183 LFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYF 242
L+S DF +DA ++RSL + +R+ +++SKWL EP FV A D VYF
Sbjct: 186 LYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGD-------HVYF 238
Query: 243 FFKEKLTDNNRSTKQIHSMIARICPNDTGGL-RSLVNKWTTFLKARLVCSVTDEDGPETH 301
FF+E ++ R + S +AR+C D GG R+L WT+FLK RL CSV + +
Sbjct: 239 FFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDS--TFY 296
Query: 302 FDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNH 361
FD L+ + + R+ L +G+FTT ++ GSAVC ++L +I+ F G F + +
Sbjct: 297 FDVLQALTGPVNLHGRSAL-FGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDG 355
Query: 362 QLISY-QGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLI 420
+ R+P PRPG+C G ++++ PDDV+TFI+ HPL+ ++ P+ +PL+
Sbjct: 356 AWTPVSEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLL 415
Query: 421 VRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVF 480
+ + T++AVD + V+FLG++ GTV KV+ + ++LEE++ +
Sbjct: 416 T-LTSRALLTQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILLEEIDAY 474
Query: 481 -----------KNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARD 529
+ I +++ ++ +L+V+ + + + L RC +G C ++D
Sbjct: 475 SPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQD 534
Query: 530 PYCAW 534
PYC W
Sbjct: 535 PYCGW 539
>gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens]
Length = 666
Score = 212 bits (539), Expect = 1e-54
Identities = 166/545 (30%), Positives = 253/545 (46%), Gaps = 56/545 (10%)
Query: 112 CGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPN 171
C N++ +++ + L CG+ A P C L G V + +G F+P+
Sbjct: 126 CENYITLLERRSEG-LLACGTNARHPSCWNLVNGT-----VVPLGEM----RGYAPFSPD 175
Query: 172 VNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPD 231
N++ + +E++S + FR + + + T + + P F+ A ++
Sbjct: 176 ENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYT---SDTVMQNPQFIKATIVHQ 232
Query: 232 GTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSL-VNKWTTFLKARLVC 290
+D K+Y+FF+E D N S +A++C D GG SL V+KW TFLKA LVC
Sbjct: 233 DQAYDD-KIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVC 291
Query: 291 SVTDEDGPETHFDELEDVFLLETDNP--RTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTV 348
S + +F+ L+DVFLL + R T VYG+F S+ + SAVCVY L DI V
Sbjct: 292 S---DAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVF---SNPWNYSAVCVYSLGDIDKV 345
Query: 349 FNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMY 408
F L Y +P PRPG C + + P + HP +
Sbjct: 346 FR---------TSSLKGYHSSLPNPRPGKC--------LPDQQPIPTETFQVADRHPEVA 388
Query: 409 NSIYPIH--KRPLIVRIGTDYKYTKIAVDRVNAADGR-YHVLFLGTDRGTVQKVVVLPTN 465
+ P+ K PL + Y Y K+AV R+ A+ G +HVL+L TDRGT+ KVV P
Sbjct: 389 QRVEPMGPLKTPLF---HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVE-PGE 444
Query: 466 NSVSGELILEELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCC 525
S + E++ F+ A I TM + +++++LYVSS VSQV L C +YG C C
Sbjct: 445 QEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCL 504
Query: 526 LARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVKN 585
++RDPYC WD C Y RS Q + P +C N K + + V N
Sbjct: 505 MSRDPYCGWDQGRCISIY--SSERSVLQSINPAEPHKECP--NPKPDKAPLQKVSL-APN 559
Query: 586 NTTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIA 645
+ +L C +S A+ W +++ ++ E + + L I ++ G Y C A
Sbjct: 560 SRYYLSCPMESRHATYSWRHKENVEQSCEPGHQ----SPNCILFIENLTAQQYGHYFCEA 615
Query: 646 TENSF 650
E S+
Sbjct: 616 QEGSY 620
>gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens]
Length = 652
Score = 212 bits (539), Expect = 1e-54
Identities = 166/545 (30%), Positives = 253/545 (46%), Gaps = 56/545 (10%)
Query: 112 CGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPN 171
C N++ +++ + L CG+ A P C L G V + +G F+P+
Sbjct: 112 CENYITLLERRSEG-LLACGTNARHPSCWNLVNGT-----VVPLGEM----RGYAPFSPD 161
Query: 172 VNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPD 231
N++ + +E++S + FR + + + T + + P F+ A ++
Sbjct: 162 ENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYT---SDTVMQNPQFIKATIVHQ 218
Query: 232 GTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSL-VNKWTTFLKARLVC 290
+D K+Y+FF+E D N S +A++C D GG SL V+KW TFLKA LVC
Sbjct: 219 DQAYDD-KIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVC 277
Query: 291 SVTDEDGPETHFDELEDVFLLETDNP--RTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTV 348
S + +F+ L+DVFLL + R T VYG+F S+ + SAVCVY L DI V
Sbjct: 278 S---DAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVF---SNPWNYSAVCVYSLGDIDKV 331
Query: 349 FNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMY 408
F L Y +P PRPG C + + P + HP +
Sbjct: 332 FR---------TSSLKGYHSSLPNPRPGKC--------LPDQQPIPTETFQVADRHPEVA 374
Query: 409 NSIYPIH--KRPLIVRIGTDYKYTKIAVDRVNAADGR-YHVLFLGTDRGTVQKVVVLPTN 465
+ P+ K PL + Y Y K+AV R+ A+ G +HVL+L TDRGT+ KVV P
Sbjct: 375 QRVEPMGPLKTPLF---HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVE-PGE 430
Query: 466 NSVSGELILEELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCC 525
S + E++ F+ A I TM + +++++LYVSS VSQV L C +YG C C
Sbjct: 431 QEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCL 490
Query: 526 LARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVKN 585
++RDPYC WD C Y RS Q + P +C N K + + V N
Sbjct: 491 MSRDPYCGWDQGRCISIY--SSERSVLQSINPAEPHKECP--NPKPDKAPLQKVSL-APN 545
Query: 586 NTTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIA 645
+ +L C +S A+ W +++ ++ E + + L I ++ G Y C A
Sbjct: 546 SRYYLSCPMESRHATYSWRHKENVEQSCEPGHQ----SPNCILFIENLTAQQYGHYFCEA 601
Query: 646 TENSF 650
E S+
Sbjct: 602 QEGSY 606
>gi|225637524 semaphorin 7A isoform 3 [Homo sapiens]
Length = 501
Score = 207 bits (528), Expect = 2e-53
Identities = 155/494 (31%), Positives = 234/494 (47%), Gaps = 46/494 (9%)
Query: 163 KGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPM 222
+G F+P+ N++ + +E++S + FR + + + T + + P
Sbjct: 2 RGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYT---SDTVMQNPQ 58
Query: 223 FVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSL-VNKWT 281
F+ A ++ +D K+Y+FF+E D N S +A++C D GG SL V+KW
Sbjct: 59 FIKATIVHQDQAYDD-KIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWN 117
Query: 282 TFLKARLVCSVTDEDGPETHFDELEDVFLLETDNP--RTTLVYGIFTTSSSVFKGSAVCV 339
TFLKA LVCS + +F+ L+DVFLL + R T VYG+F S+ + SAVCV
Sbjct: 118 TFLKAMLVCS---DAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVF---SNPWNYSAVCV 171
Query: 340 YHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVT 399
Y L DI VF L Y +P PRPG C + + P +
Sbjct: 172 YSLGDIDKVFR---------TSSLKGYHSSLPNPRPGKC--------LPDQQPIPTETFQ 214
Query: 400 FIRNHPLMYNSIYPIH--KRPLIVRIGTDYKYTKIAVDRVNAADGR-YHVLFLGTDRGTV 456
HP + + P+ K PL + Y Y K+AV R+ A+ G +HVL+L TDRGT+
Sbjct: 215 VADRHPEVAQRVEPMGPLKTPLF---HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTI 271
Query: 457 QKVVVLPTNNSVSGELILEELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHI 516
KVV P S + E++ F+ A I TM + +++++LYVSS VSQV L C +
Sbjct: 272 HKVVE-PGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEV 330
Query: 517 YGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAA 576
YG C C ++RDPYC WD C Y RS Q + P +C N K +
Sbjct: 331 YGGGCHGCLMSRDPYCGWDQGRCISIY--SSERSVLQSINPAEPHKECP--NPKPDKAPL 386
Query: 577 EIVQYGVKNNTTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQGS 636
+ V N+ +L C +S A+ W +++ ++ E + + L I ++
Sbjct: 387 QKVSL-APNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQ----SPNCILFIENLTAQ 441
Query: 637 DQGLYHCIATENSF 650
G Y C A E S+
Sbjct: 442 QYGHYFCEAQEGSY 455
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,157,299
Number of Sequences: 37866
Number of extensions: 1344877
Number of successful extensions: 3445
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 3044
Number of HSP's gapped (non-prelim): 256
length of query: 751
length of database: 18,247,518
effective HSP length: 110
effective length of query: 641
effective length of database: 14,082,258
effective search space: 9026727378
effective search space used: 9026727378
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.