Guide to the Human Genome
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Name: NNMT Sequence: fasta or formatted (264aa) NCBI GI: 5453790
Description:

nicotinamide N-methyltransferase

Referenced in:

Vitamin Pathways, Coenzymes, and 1-Carbon Metabolism

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.1         16           2
 C cysteine            3.0          8           1
 D aspartate           5.3         14           1
 E glutamate           7.6         20           2
 F phenylalanine       4.2         11           1
 G glycine             6.1         16           2
 H histidine           1.1          3           1
 I isoleucine          3.8         10           1
 K lysine              8.0         21           2
 L leucine            13.3         35           2
 M methionine          1.5          4           1
 N asparagine          2.7          7           2
 P proline             5.3         14           2
 Q glutamine           3.8         10           1
 R arginine            3.4          9           1
 S serine              9.1         24           2
 T threonine           3.8         10           1
 V valine              6.4         17           2
 W tryptophan          1.1          3           1
 Y tyrosine            4.5         12           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   nicotinamide N-methyltransferase 
INMT                  0.480   indolethylamine N-methyltransferase 
PNMT                  0.288   phenylethanolamine N-methyltransferase 
METTL6                0.024   methyltransferase like 6 
METTL2B               0.016   methyltransferase like 2B 
METTL2A               0.016   methyltransferase like 2A 
FOXB1                 0.010   forkhead box B1 
FASN                  0.008   fatty acid synthase 
PANK1                 0.008   pantothenate kinase 1 isoform gamma 
C7orf63               0.006   hypothetical protein LOC79846 isoform 2 
C7orf63               0.006   hypothetical protein LOC79846 isoform 1 
NAALAD2               0.006   N-acetylated alpha-linked acidic dipeptidase 2 
MAP3K1                0.006   mitogen-activated protein kinase kinase kinase 1 [H...
DENND2D               0.006   DENN/MADD domain containing 2D 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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