Guide to the Human Genome
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Search of human proteins with 134053883

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|134053883 intestinal facilitative glucose transporter 7
[Homo sapiens]
         (512 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|134053883 intestinal facilitative glucose transporter 7 [Homo...  1001   0.0  
gi|4507013 solute carrier family 2 (facilitated glucose/fructose...   598   e-171
gi|47933389 solute carrier family 2, member 9 protein isoform 2 ...   431   e-121
gi|47933387 solute carrier family 2, member 9 protein isoform 1 ...   431   e-121
gi|4507011 glucose transporter 4 [Homo sapiens]                       382   e-106
gi|166795299 solute carrier family 2 (facilitated glucose transp...   380   e-105
gi|190684655 glucose transporter protein 10 isoform a [Homo sapi...   374   e-103
gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]   374   e-103
gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]   373   e-103
gi|5902090 solute carrier family 2 (facilitated glucose transpor...   366   e-101
gi|23592238 glucose transporter 14 [Homo sapiens]                     353   2e-97
gi|4557851 solute carrier family 2 (facilitated glucose transpor...   317   2e-86
gi|207447703 solute carrier family 2 (facilitated glucose/fructo...   226   5e-59
gi|21361449 solute carrier family 2 (facilitated glucose transpo...   150   3e-36
gi|223029432 solute carrier family 2 (facilitated glucose transp...   138   1e-32
gi|203098995 solute carrier family 2 (facilitated glucose transp...   130   3e-30
gi|223029430 solute carrier family 2 (facilitated glucose transp...   128   1e-29
gi|21553331 solute carrier family 2 (facilitated glucose transpo...   121   2e-27
gi|13540547 solute carrier family 2 member 10 [Homo sapiens]          106   4e-23
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap...    70   5e-12
gi|213021148 SVOP-like isoform 1 [Homo sapiens]                        64   3e-10
gi|170650643 solute carrier family 22, member 23 isoform a [Homo...    63   7e-10
gi|4507001 solute carrier family 22 member 2 [Homo sapiens]            60   4e-09
gi|4507005 solute carrier family 22 member 5 [Homo sapiens]            60   4e-09
gi|11415038 solute carrier family 22 member 3 [Homo sapiens]           60   6e-09
gi|24497480 solute carrier family 22 member 6 isoform d [Homo sa...    57   5e-08
gi|24497478 solute carrier family 22 member 6 isoform c [Homo sa...    57   5e-08
gi|24497476 solute carrier family 22 member 6 isoform b [Homo sa...    57   5e-08
gi|20070188 solute carrier family 22 member 6 isoform a [Homo sa...    57   5e-08
gi|24308167 SV2 related protein [Homo sapiens]                         57   5e-08

>gi|134053883 intestinal facilitative glucose transporter 7 [Homo
           sapiens]
          Length = 512

 Score = 1001 bits (2589), Expect = 0.0
 Identities = 512/512 (100%), Positives = 512/512 (100%)

Query: 1   MENKEAGTPPPIPSREGRLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETY 60
           MENKEAGTPPPIPSREGRLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETY
Sbjct: 1   MENKEAGTPPPIPSREGRLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETY 60

Query: 61  FERHATFMDGKLMLLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAI 120
           FERHATFMDGKLMLLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAI
Sbjct: 61  FERHATFMDGKLMLLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAI 120

Query: 121 LMGVSKVAKAFELIVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGV 180
           LMGVSKVAKAFELIVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGV
Sbjct: 121 LMGVSKVAKAFELIVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGV 180

Query: 181 FLAQIFSLQAILGNPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQAL 240
           FLAQIFSLQAILGNPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQAL
Sbjct: 181 FLAQIFSLQAILGNPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQAL 240

Query: 241 RRLRGHTDMEAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGIN 300
           RRLRGHTDMEAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGIN
Sbjct: 241 RRLRGHTDMEAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGIN 300

Query: 301 AINYYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGS 360
           AINYYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGS
Sbjct: 301 AINYYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGS 360

Query: 361 ACLVLTVVLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMV 420
           ACLVLTVVLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMV
Sbjct: 361 ACLVLTVVLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMV 420

Query: 421 DGAVHWLTNFIIGFLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRI 480
           DGAVHWLTNFIIGFLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRI
Sbjct: 421 DGAVHWLTNFIIGFLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRI 480

Query: 481 FAKRNRVKLPEEKEETIDAGPPTASPAKETSF 512
           FAKRNRVKLPEEKEETIDAGPPTASPAKETSF
Sbjct: 481 FAKRNRVKLPEEKEETIDAGPPTASPAKETSF 512


>gi|4507013 solute carrier family 2 (facilitated glucose/fructose
           transporter), member 5 isoform 1 [Homo sapiens]
          Length = 501

 Score =  598 bits (1542), Expect = e-171
 Identities = 296/491 (60%), Positives = 377/491 (76%), Gaps = 1/491 (0%)

Query: 15  REGRLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLML 74
           +EGRL   L LATL AAFGS+FQYGYN++ VN+P  + + FYNETY+ R   FM+   + 
Sbjct: 9   KEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLT 68

Query: 75  LLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELI 134
           LLWS TVSMFP GG +GSLLVG LV+  GRKG LL NNIF+I+PAILMG S+VA +FELI
Sbjct: 69  LLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELI 128

Query: 135 VFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGN 194
           + SR+++G+CAG+S + +PMYLGELAPKNLRG +G + ++F+ VG+ +AQIF L+ +L N
Sbjct: 129 IISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLAN 188

Query: 195 PAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELE 254
             GWP+LL LTGVPA LQLL LPFFPESPRY LIQK DEA A++AL+ LRG   ++ E+ 
Sbjct: 189 VDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVA 248

Query: 255 DMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAG 314
           ++R E  AE+A G +SVL L  +RSLRWQLLSIIVLM GQQLSG+NAI YYAD IY SAG
Sbjct: 249 EIRQEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAG 308

Query: 315 VEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNR 374
           V   H QYVT G+G VN+VMT  +  +VE LGRR LLL G+ IC  AC VLT  L  Q+ 
Sbjct: 309 VPEEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDT 368

Query: 375 VPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGF 434
           V  + Y+ I+CV +Y+ GH++GPSP+P+++ TEIFLQSSR +AFMV G+VHWL+NF +G 
Sbjct: 369 VSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGL 428

Query: 435 LFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKRNRV-KLPEEK 493
           +FP IQE +G YSFI+FA ICLLT IYI++++PETK KTF+EIN+IF K N+V ++  EK
Sbjct: 429 IFPFIQEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMNKVSEVYPEK 488

Query: 494 EETIDAGPPTA 504
           EE  +  P T+
Sbjct: 489 EELKELPPVTS 499


>gi|47933389 solute carrier family 2, member 9 protein isoform 2
           [Homo sapiens]
          Length = 511

 Score =  431 bits (1109), Expect = e-121
 Identities = 212/472 (44%), Positives = 316/472 (66%)

Query: 22  TLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLMLLLWSCTV 81
           +LL+A+L+ AFGS+F YGYNLSVVN P    K+FYNE++  RH   +D   + LLWS TV
Sbjct: 26  SLLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTV 85

Query: 82  SMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVVL 141
           S+F +GGL+G+L+V ++    GRK TLL NN FAI  A+LM  S  A AFE+++  R ++
Sbjct: 86  SIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIM 145

Query: 142 GVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPVL 201
           G+  G++ S LPMYL E++PK +RG +G +T +F+ +GVF  Q+  L  +LG  + WP L
Sbjct: 146 GIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYL 205

Query: 202 LALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMRAEAR 261
             +  VPA++QLL+LPF P+SPRY L++K +EA A +A +   G  D+  E+E++ AE+R
Sbjct: 206 FGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESR 265

Query: 262 AERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAGVEAAHSQ 321
            +R+   +SVL L     +RWQ++++IV MA  QL G+NAI +Y ++I+  AG+  A   
Sbjct: 266 VQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIP 325

Query: 322 YVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNRVPELSYL 381
           YVT+ +G +  +  + S +++E LGRR LL+ G+G+ G     LT+ L  Q+  P + YL
Sbjct: 326 YVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYL 385

Query: 382 GIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFPSIQE 441
            I+ + A IA    GP  +P ++  E F QS R AAF++ G V+WL+NF +G LFP IQ+
Sbjct: 386 SIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQK 445

Query: 442 AIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKRNRVKLPEEK 493
           ++  Y F++FA IC+  AIY+Y V+PETK +T+ EI++ F+KRN+   PEEK
Sbjct: 446 SLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAYPPEEK 497


>gi|47933387 solute carrier family 2, member 9 protein isoform 1
           [Homo sapiens]
          Length = 540

 Score =  431 bits (1109), Expect = e-121
 Identities = 212/472 (44%), Positives = 316/472 (66%)

Query: 22  TLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLMLLLWSCTV 81
           +LL+A+L+ AFGS+F YGYNLSVVN P    K+FYNE++  RH   +D   + LLWS TV
Sbjct: 55  SLLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTV 114

Query: 82  SMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVVL 141
           S+F +GGL+G+L+V ++    GRK TLL NN FAI  A+LM  S  A AFE+++  R ++
Sbjct: 115 SIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIM 174

Query: 142 GVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPVL 201
           G+  G++ S LPMYL E++PK +RG +G +T +F+ +GVF  Q+  L  +LG  + WP L
Sbjct: 175 GIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYL 234

Query: 202 LALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMRAEAR 261
             +  VPA++QLL+LPF P+SPRY L++K +EA A +A +   G  D+  E+E++ AE+R
Sbjct: 235 FGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESR 294

Query: 262 AERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAGVEAAHSQ 321
            +R+   +SVL L     +RWQ++++IV MA  QL G+NAI +Y ++I+  AG+  A   
Sbjct: 295 VQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIP 354

Query: 322 YVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNRVPELSYL 381
           YVT+ +G +  +  + S +++E LGRR LL+ G+G+ G     LT+ L  Q+  P + YL
Sbjct: 355 YVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYL 414

Query: 382 GIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFPSIQE 441
            I+ + A IA    GP  +P ++  E F QS R AAF++ G V+WL+NF +G LFP IQ+
Sbjct: 415 SIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQK 474

Query: 442 AIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKRNRVKLPEEK 493
           ++  Y F++FA IC+  AIY+Y V+PETK +T+ EI++ F+KRN+   PEEK
Sbjct: 475 SLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAYPPEEK 526


>gi|4507011 glucose transporter 4 [Homo sapiens]
          Length = 509

 Score =  382 bits (982), Expect = e-106
 Identities = 202/497 (40%), Positives = 311/497 (62%), Gaps = 14/497 (2%)

Query: 5   EAGTPPPIPSREGRLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERH 64
           E G PP     + R+  TL+LA  SA  GS  Q+GYN+ V+N P KV +  YNET+  R 
Sbjct: 11  EDGEPP-----QQRVTGTLVLAVFSAVLGS-LQFGYNIGVINAPQKVIEQSYNETWLGRQ 64

Query: 65  ATFMDGKL----MLLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAI 120
                  +    +  LW+ +V++F +GG++ S L+G++    GRK  +L+NN+ A++   
Sbjct: 65  GPEGPSSIPPGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGS 124

Query: 121 LMGVSKVAKAFELIVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGV 180
           LMG++  A ++E+++  R ++G  +G++   +PMY+GE+AP +LRG +GT+ ++ +++G+
Sbjct: 125 LMGLANAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGI 184

Query: 181 FLAQIFSLQAILGNPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQAL 240
            +AQ+  L+++LG  + WP+LL LT +PALLQL+ LPF PESPRY  I +  E  AR++L
Sbjct: 185 LIAQVLGLESLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSL 244

Query: 241 RRLRGHTDMEAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGIN 300
           +RL G  D+   L +++ E R    E  LS+L L   R+ R  L+  +VL   QQLSGIN
Sbjct: 245 KRLTGWADVSGVLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGIN 304

Query: 301 AINYYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGY-GICG 359
           A+ YY+ +I+ +AGV      Y T+G+GVVN V T+ S +LVER GRR L L G  G+CG
Sbjct: 305 AVFYYSTSIFETAGV--GQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCG 362

Query: 360 SACLVLTVVLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFM 419
            A +++TV LL   RVP +SY+ I+ +F ++A   IGP P+P  +  E+F Q  R AA  
Sbjct: 363 CA-ILMTVALLLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMA 421

Query: 420 VDGAVHWLTNFIIGFLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINR 479
           V G  +W +NFIIG  F  + EA+G Y F++FA + L   I+ ++ +PET+G+TF +I+ 
Sbjct: 422 VAGFSNWTSNFIIGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISA 481

Query: 480 IFAKRNRVKLPEEKEET 496
            F +   +   E K  T
Sbjct: 482 AFHRTPSLLEQEVKPST 498


>gi|166795299 solute carrier family 2 (facilitated glucose
           transporter), member 1 [Homo sapiens]
          Length = 492

 Score =  380 bits (977), Expect = e-105
 Identities = 191/478 (39%), Positives = 298/478 (62%), Gaps = 6/478 (1%)

Query: 18  RLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLMLLLW 77
           +L   L+LA   A  GS  Q+GYN  V+N P KV + FYN+T+  R+   +    +  LW
Sbjct: 7   KLTGRLMLAVGGAVLGS-LQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLW 65

Query: 78  SCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFS 137
           S +V++F +GG++GS  VGL V+  GR+ ++L+ N+ A + A+LMG SK+ K+FE+++  
Sbjct: 66  SLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILG 125

Query: 138 RVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAG 197
           R ++GV  G++   +PMY+GE++P  LRG +GT+ ++ ++VG+ +AQ+F L +I+GN   
Sbjct: 126 RFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDL 185

Query: 198 WPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMR 257
           WP+LL++  +PALLQ + LPF PESPR+ LI + +E  A+  L++LRG  D+  +L++M+
Sbjct: 186 WPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMK 245

Query: 258 AEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAGVEA 317
            E+R    E  +++L L    + R  +L  +VL   QQLSGINA+ YY+ +I+  AGV+ 
Sbjct: 246 EESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQ- 304

Query: 318 AHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNRVPE 377
               Y T+GSG+VN   T+ S  +VER GRR L L G        +++T+ L    ++P 
Sbjct: 305 -QPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQLPW 363

Query: 378 LSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFP 437
           +SYL I+ +F ++A   +GP P+P  +  E+F Q  R AA  V G  +W +NFI+G  F 
Sbjct: 364 MSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQ 423

Query: 438 SIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAK---RNRVKLPEE 492
            +++  G Y FIIF  + +L  I+ Y  +PETKG+TF EI   F +       K PEE
Sbjct: 424 YVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPEE 481


>gi|190684655 glucose transporter protein 10 isoform a [Homo
           sapiens]
          Length = 503

 Score =  374 bits (960), Expect = e-103
 Identities = 201/485 (41%), Positives = 292/485 (60%), Gaps = 3/485 (0%)

Query: 1   MENKEAGTPPPIPSREGRLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETY 60
           ME++   +  P    +GR+   LLL   +A  G  FQ+GYNLS++N P    + F NET+
Sbjct: 1   MEDELEPSLRPRTQIQGRI---LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETW 57

Query: 61  FERHATFMDGKLMLLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAI 120
             R    +   L+LL+WS  VS++PLGGL G+LL G L  + GRK +LL+NNIF +  AI
Sbjct: 58  QARTGEPLPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAI 117

Query: 121 LMGVSKVAKAFELIVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGV 180
           L G S+ A +FE+I+  R+++GV AG+S +  PMYLGE APK LRG V   + +F  +G+
Sbjct: 118 LFGFSRKAGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGI 177

Query: 181 FLAQIFSLQAILGNPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQAL 240
            + Q+  L+ +LG P  WP+LLA   VP  LQL +LP  PESPRY LI  GD      AL
Sbjct: 178 VMGQVVGLRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAAL 237

Query: 241 RRLRGHTDMEAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGIN 300
           RRLRG  D+  ELE++  E  A +         L   R+LR Q+ S++VL +  +L G +
Sbjct: 238 RRLRGSGDLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGND 297

Query: 301 AINYYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGS 360
           ++  YA +++  AGV  A  QY  +G+G   ++  + S V++ER+GRR LL+ GY +   
Sbjct: 298 SVYAYASSVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTC 357

Query: 361 ACLVLTVVLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMV 420
              + TV L  Q+  P   YL + C+FA+I    IGP+ V  ++ TE+F Q +R AA MV
Sbjct: 358 WGSIFTVALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMV 417

Query: 421 DGAVHWLTNFIIGFLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRI 480
            GA+ W+   ++G  FP I EA+  + ++ F G+C+  AIY  + +PETKGKTF EI++ 
Sbjct: 418 CGALMWIMLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKE 477

Query: 481 FAKRN 485
             + N
Sbjct: 478 LHRLN 482


>gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]
          Length = 499

 Score =  374 bits (959), Expect = e-103
 Identities = 199/472 (42%), Positives = 287/472 (60%), Gaps = 1/472 (0%)

Query: 15  REGRLQPTLLLATLSAA-FGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLM 73
           R   +Q  +LL T+ AA  G  FQ+GYNLS++N P    + F NET+  R    +   L+
Sbjct: 7   RSRMIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLV 66

Query: 74  LLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFEL 133
           LL+WS  VS++PLGGL G+LL G L  + GRK +LL+NNIF +  AIL G S+ A +FE+
Sbjct: 67  LLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEM 126

Query: 134 IVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILG 193
           I+  R+++GV AG+S +  PMYLGE APK LRG V   + +F  +G+ + Q+  L+ +LG
Sbjct: 127 IMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLG 186

Query: 194 NPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAEL 253
            P  WP+LLA   VP  LQL +LP  PESPRY LI  GD      ALRRLRG  D+  EL
Sbjct: 187 GPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGEL 246

Query: 254 EDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSA 313
           E++  E  A +         L   R+LR Q+ S++VL +  +L G +++  YA +++  A
Sbjct: 247 EELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKA 306

Query: 314 GVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQN 373
           GV  A  QY  +G+G   ++  + S V++ER+GRR LL+ GY +      + TV L  Q+
Sbjct: 307 GVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQS 366

Query: 374 RVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIG 433
             P   YL + C+FA+I    IGP+ V  ++ TE+F Q +R AA MV GA+ W+   ++G
Sbjct: 367 SFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVG 426

Query: 434 FLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKRN 485
             FP I EA+  + ++ F G+C+  AIY  + +PETKGKTF EI++   + N
Sbjct: 427 LGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLN 478


>gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]
          Length = 496

 Score =  373 bits (958), Expect = e-103
 Identities = 198/470 (42%), Positives = 286/470 (60%), Gaps = 3/470 (0%)

Query: 16  EGRLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLMLL 75
           +GR+   LLL   +A  G  FQ+GYNLS++N P    + F NET+  R    +   L+LL
Sbjct: 9   QGRI---LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLL 65

Query: 76  LWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIV 135
           +WS  VS++PLGGL G+LL G L  + GRK +LL+NNIF +  AIL G S+ A +FE+I+
Sbjct: 66  MWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIM 125

Query: 136 FSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNP 195
             R+++GV AG+S +  PMYLGE APK LRG V   + +F  +G+ + Q+  L+ +LG P
Sbjct: 126 LGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGP 185

Query: 196 AGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELED 255
             WP+LLA   VP  LQL +LP  PESPRY LI  GD      ALRRLRG  D+  ELE+
Sbjct: 186 QAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEE 245

Query: 256 MRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAGV 315
           +  E  A +         L   R+LR Q+ S++VL +  +L G +++  YA +++  AGV
Sbjct: 246 LEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGV 305

Query: 316 EAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNRV 375
             A  QY  +G+G   ++  + S V++ER+GRR LL+ GY +      + TV L  Q+  
Sbjct: 306 PEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSF 365

Query: 376 PELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFL 435
           P   YL + C+FA+I    IGP+ V  ++ TE+F Q +R AA MV GA+ W+   ++G  
Sbjct: 366 PWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLG 425

Query: 436 FPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKRN 485
           FP I EA+  + ++ F G+C+  AIY  + +PETKGKTF EI++   + N
Sbjct: 426 FPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLN 475


>gi|5902090 solute carrier family 2 (facilitated glucose
           transporter), member 3 [Homo sapiens]
          Length = 496

 Score =  366 bits (939), Expect = e-101
 Identities = 193/494 (39%), Positives = 297/494 (60%), Gaps = 5/494 (1%)

Query: 18  RLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLMLLLW 77
           ++ P L+ A   A  GS FQ+GYN  V+N P K+ K F N+T  ++        L+  LW
Sbjct: 5   KVTPALIFAITVATIGS-FQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLW 63

Query: 78  SCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFS 137
           S +V++F +GG++GS  VGL V+  GR+ ++LI N+ A+     MG+ KVAK+ E+++  
Sbjct: 64  SLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILG 123

Query: 138 RVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAG 197
           R+V+G+  G+    +PMY+GE++P  LRG  GT+ ++ ++VG+ +AQIF L+ ILG+   
Sbjct: 124 RLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEEL 183

Query: 198 WPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMR 257
           WP+LL  T +PA+LQ   LPF PESPR+ LI + +E  A+Q L+RL G  D+  ++++M+
Sbjct: 184 WPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMK 243

Query: 258 AEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAGVEA 317
            E+     E  ++VL L  + S R  ++  IVL   QQLSGINA+ YY+  I+  AGV+ 
Sbjct: 244 DESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQ- 302

Query: 318 AHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNRVPE 377
               Y T+G+GVVN + T+ S  LVER GRR L + G G       ++TV LL ++    
Sbjct: 303 -EPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNG 361

Query: 378 LSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFP 437
           +S++ I  +  ++A   IGP P+P  +  E+F Q  R AA  V G  +W +NF++G LFP
Sbjct: 362 MSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFP 421

Query: 438 SIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKRNRVKLPEEKEETI 497
           S    +GAY FIIF G  +    + +  +PET+G+TF +I R F  +        K+  +
Sbjct: 422 SAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGVM 481

Query: 498 DAGPPTASPAKETS 511
           +    +  PAKET+
Sbjct: 482 EMN--SIEPAKETT 493


>gi|23592238 glucose transporter 14 [Homo sapiens]
          Length = 520

 Score =  353 bits (906), Expect = 2e-97
 Identities = 190/491 (38%), Positives = 290/491 (59%), Gaps = 5/491 (1%)

Query: 21  PTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLMLLLWSCT 80
           P L+ A   A  GS FQ+GYN  V+N P  + K F N+T  ++        L+  LWS +
Sbjct: 32  PALIFAITVATIGS-FQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLS 90

Query: 81  VSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVV 140
           V++F +GG++GS  VGL V+  GR+ ++LI N+ A     LMG+ K+A++ E+++  R+V
Sbjct: 91  VAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLV 150

Query: 141 LGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPV 200
           +G+  G+    +PMY+GE++P  LRG  GT+ ++ +++G+ +AQIF L+ ILG+   WPV
Sbjct: 151 IGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPV 210

Query: 201 LLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMRAEA 260
           LL  T +PA+LQ   LP  PESPR+ LI +  E  A + L+RL G  D+  ++++M+ E+
Sbjct: 211 LLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDES 270

Query: 261 RAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAGVEAAHS 320
                E  ++VL L  + S R  ++  IVL   QQLSGINA+ YY+  I+  AGV+    
Sbjct: 271 ARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQ--QP 328

Query: 321 QYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNRVPELSY 380
            Y T+ +GVVN + T+ S  LVER GRR L + G G       ++TV LL +N    +S+
Sbjct: 329 IYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSF 388

Query: 381 LGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFPSIQ 440
           + I  +  ++A   IGP P+P  +  E+F Q  R AA  V G  +W +NF++G LFPS  
Sbjct: 389 VCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAA 448

Query: 441 EAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKRNRVKLPEEKEETIDAG 500
             +GAY FIIF G  +    + +  +PET+G+TF +I R F  +        K+  +  G
Sbjct: 449 YYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGVM--G 506

Query: 501 PPTASPAKETS 511
             +  PAKET+
Sbjct: 507 MNSIEPAKETT 517


>gi|4557851 solute carrier family 2 (facilitated glucose
           transporter), member 2 [Homo sapiens]
          Length = 524

 Score =  317 bits (811), Expect = 2e-86
 Identities = 177/504 (35%), Positives = 275/504 (54%), Gaps = 37/504 (7%)

Query: 16  EGRLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNE----------------- 58
           E ++  TL+   ++A  GS FQ+GY++ V+N P +V  S Y                   
Sbjct: 3   EDKVTGTLVFTVITAVLGS-FQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYVI 61

Query: 59  -----------------TYFERHATFMDGKLMLLLWSCTVSMFPLGGLLGSLLVGLLVDS 101
                            T +    T    +L+ +LWS +VS F +GG+  S   G L D+
Sbjct: 62  NSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDT 121

Query: 102 CGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVVLGVCAGISYSALPMYLGELAP 161
            GR   +L+ NI +++ A+LMG SK+  +  LI+  R + G+  G+    +PMY+GE+AP
Sbjct: 122 LGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAP 181

Query: 162 KNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPVLLALTGVPALLQLLTLPFFPE 221
             LRG +GT  ++ ++ G+ ++QI  L+ ILGN   W +LL L+GV A+LQ L L F PE
Sbjct: 182 TALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPE 241

Query: 222 SPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMRAEARAERAEGHLSVLHLCALRSLR 281
           SPRY  I+  +E  A+Q+L+RLRG+ D+  ++ +MR E     +E  +S++ L    S R
Sbjct: 242 SPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYR 301

Query: 282 WQLLSIIVLMAGQQLSGINAINYYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVL 341
             +L  ++L   QQ SGIN I YY+ +I+ +AG+  +   Y T+G G VN+V T  S  L
Sbjct: 302 QPILVALMLHVAQQFSGINGIFYYSTSIFQTAGI--SKPVYATIGVGAVNMVFTAVSVFL 359

Query: 342 VERLGRRHLLLAGYGICGSACLVLTVVLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVP 401
           VE+ GRR L L G        + ++V L+  N+   +SY+ +I +F +++   IGP P+P
Sbjct: 360 VEKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIP 419

Query: 402 SVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFPSIQEAIGAYSFIIFAGICLLTAIY 461
             +  E F Q  R AA  +    +W  NFI+   F  I +  G Y F +FAG+ L   ++
Sbjct: 420 WFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLF 479

Query: 462 IYVVIPETKGKTFVEINRIFAKRN 485
            +  +PETKGK+F EI   F K++
Sbjct: 480 TFFKVPETKGKSFEEIAAEFQKKS 503


>gi|207447703 solute carrier family 2 (facilitated glucose/fructose
           transporter), member 5 isoform 2 [Homo sapiens]
          Length = 244

 Score =  226 bits (575), Expect = 5e-59
 Identities = 109/183 (59%), Positives = 142/183 (77%)

Query: 15  REGRLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLML 74
           +EGRL   L LATL AAFGS+FQYGYN++ VN+P  + + FYNETY+ R   FM+   + 
Sbjct: 9   KEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLT 68

Query: 75  LLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELI 134
           LLWS TVSMFP GG +GSLLVG LV+  GRKG LL NNIF+I+PAILMG S+VA +FELI
Sbjct: 69  LLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELI 128

Query: 135 VFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGN 194
           + SR+++G+CAG+S + +PMYLGELAPKNLRG +G + ++F+ VG+ +AQIF L+ +L N
Sbjct: 129 IISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLAN 188

Query: 195 PAG 197
             G
Sbjct: 189 VDG 191


>gi|21361449 solute carrier family 2 (facilitated glucose
           transporter), member 8 [Homo sapiens]
          Length = 477

 Score =  150 bits (379), Expect = 3e-36
 Identities = 126/429 (29%), Positives = 205/429 (47%), Gaps = 59/429 (13%)

Query: 86  LGGLLGSLLVGLLVDSCGRKGTLLINNI-----FAIIPAILMGVSKVAKAFELIVFSRVV 140
           LG   G +L G LVD  GRK +LL+ ++     FA+I A        A+   +++  R++
Sbjct: 78  LGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITA--------AQDVWMLLGGRLL 129

Query: 141 LGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPV 200
            G+  G++    P+Y+ E+A   +RG++G+  ++ V+VG+ LA +       G    W  
Sbjct: 130 TGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYL------AGWVLEWRW 183

Query: 201 LLALTGVPALLQLLTLPFFPESPRYSLIQ-KGDEATARQALRRLRGHTDMEAELEDMRAE 259
           L  L  VP  L LL + F PE+PR+ L Q +  EA A  ALR L G    E   ED    
Sbjct: 184 LAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMA--ALRFLWGS---EQGWEDPPIG 238

Query: 260 ARAERAEGHLSVLHLCALRS--LRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAGVEA 317
           A            HL  LR   +    +  + LMA QQLSG+NA+ +YA+TI+  A  + 
Sbjct: 239 AEQS--------FHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFK- 289

Query: 318 AHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLL---------------------AGYG 356
             S   +V  GV+ ++ T  +A++++R GRR LL+                      G G
Sbjct: 290 -DSSLASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPG 348

Query: 357 ICGSACLVLTVVLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRA 416
                 +   V     +    L++L +  +  +IAG ++G  P+P ++ +EIF    +  
Sbjct: 349 NSSHVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGV 408

Query: 417 AFMVDGAVHWLTNFIIGFLFPSIQEAIGAY-SFIIFAGICLLTAIYIYVVIPETKGKTFV 475
           A  +    +WL  F++   F S+ E +  Y +F + +  C+ + ++    +PETKGKT  
Sbjct: 409 ATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLE 468

Query: 476 EINRIFAKR 484
           +I   F  R
Sbjct: 469 QITAHFEGR 477


>gi|223029432 solute carrier family 2 (facilitated glucose
           transporter), member 6 isoform 1 [Homo sapiens]
          Length = 507

 Score =  138 bits (347), Expect = 1e-32
 Identities = 134/511 (26%), Positives = 231/511 (45%), Gaps = 60/511 (11%)

Query: 9   PPPIP---SREGRLQ-PTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERH 64
           PPP P   +R G LQ   + LAT +A  G+ F +GY L V  +P  V  +       + H
Sbjct: 20  PPPSPGDRARVGTLQNKRVFLATFAAVLGN-FSFGYAL-VYTSP--VIPALERSLDPDLH 75

Query: 65  ATFMDGKLMLLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGV 124
            T           S   S+F LG   G L   +L D  GRK +++    F+ +P+   G 
Sbjct: 76  LTKSQA-------SWFGSVFTLGAAAGGLSAMILNDLLGRKLSIM----FSAVPSAA-GY 123

Query: 125 SKVAKAFEL--IVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFL 182
           + +A A  L  ++  R + G   G++ + +P+Y+ E+AP  +RG +G   ++  + G   
Sbjct: 124 ALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSL- 182

Query: 183 AQIFSLQAILGNPAGWPVLLALTG-VPALLQLLTLPFFPESPRYSLIQKGDEATARQALR 241
             +++L  +L  P  W   LA+ G  P L+ +L L F P SPR+ L+ +G +  A +AL 
Sbjct: 183 -SLYALGLLL--PWRW---LAVAGEAPVLIMILLLSFMPNSPRF-LLSRGRDEEALRALA 235

Query: 242 RLRGHTDMEAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINA 301
            LRG TD++   E  + +    R    +S     A    R   +++++ +  QQL+GI  
Sbjct: 236 WLRG-TDVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVCRPITVALLMRLL-QQLTGITP 293

Query: 302 INYYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSA 361
           I  Y  +I+ S  V         +  G V ++  + +A+ ++  GR+ LL     I  +A
Sbjct: 294 ILVYLQSIFDSTAVLLPPKDDAAI-VGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAA 352

Query: 362 CLVLTVVLLFQNR-------------------------VPELSYLGIICVFAYIAGHSIG 396
            L L + + F  R                            L+ + ++    +I G+++G
Sbjct: 353 NLTLGLYIHFGPRPLSPNSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVG 412

Query: 397 PSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFPSIQEAIG-AYSFIIFAGIC 455
             P+  ++ +E+    +R  A  +     WLT F++   F  +    G    F  FA IC
Sbjct: 413 WGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAIC 472

Query: 456 LLTAIYIYVVIPETKGKTFVEINRIFAKRNR 486
           L++ ++    +PETKG++  +I   F    R
Sbjct: 473 LVSLVFTGCCVPETKGRSLEQIESFFRTGRR 503


>gi|203098995 solute carrier family 2 (facilitated glucose
           transporter), member 13 [Homo sapiens]
          Length = 648

 Score =  130 bits (327), Expect = 3e-30
 Identities = 105/363 (28%), Positives = 174/363 (47%), Gaps = 27/363 (7%)

Query: 24  LLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLMLLLWSCTVSM 83
           ++A  SA  G  F +GY+  VV+    + K   +          +D     LL S TV  
Sbjct: 83  VVAVFSALGG--FLFGYDTGVVSGAMLLLKRQLS----------LDALWQELLVSSTVGA 130

Query: 84  FPLGGLLGSLLVGLLVDSCGRKGTLLINN-IFAIIPAILMGVSKVAKAFELIVFSRVVLG 142
             +  L G  L G+     GR+  +L+ + +F    A+L   +      E ++  R+V+G
Sbjct: 131 AAVSALAGGALNGVF----GRRAAILLASALFTAGSAVLAAANNK----ETLLAGRLVVG 182

Query: 143 VCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPVLL 202
           +  GI+   +P+Y+ E++P NLRG + T+  +F+  G F A +           GW  +L
Sbjct: 183 LGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYML 242

Query: 203 ALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMRAEARA 262
            L  VPA++Q     F PESPR+ LIQKG    AR+ L ++RG+  ++ E + ++     
Sbjct: 243 GLAAVPAVIQFFGFLFLPESPRW-LIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEE 301

Query: 263 ERAEGHLSVLHLCALRSLRWQLLSIIV---LMAGQQLSGINAINYYADTIYTSAGVEAAH 319
           E  E   +   +C + S      ++IV   L   QQLSGIN I YY+ TI   +GVE   
Sbjct: 302 EEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDR 361

Query: 320 -SQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNRV-PE 377
            + ++   +   N + T+    LVE++GRR L          A ++L +  +   +V P 
Sbjct: 362 LAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSPR 421

Query: 378 LSY 380
           +++
Sbjct: 422 ITF 424



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 29/107 (27%), Positives = 53/107 (49%), Gaps = 1/107 (0%)

Query: 379 SYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFPS 438
           S+  ++ +  Y+   + G  P+P  V +EI+   +R         ++W+ N ++   F  
Sbjct: 506 SWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLH 565

Query: 439 IQEAIGAY-SFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKR 484
             E +  Y +F ++AG   +  ++IY  +PETKGK   EI  +F  R
Sbjct: 566 TAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNR 612


>gi|223029430 solute carrier family 2 (facilitated glucose
           transporter), member 6 isoform 2 [Homo sapiens]
          Length = 445

 Score =  128 bits (322), Expect = 1e-29
 Identities = 126/486 (25%), Positives = 218/486 (44%), Gaps = 72/486 (14%)

Query: 9   PPPIP---SREGRLQ-PTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERH 64
           PPP P   +R G LQ   + LAT +A  G+ F +GY L V  +P  V  +       + H
Sbjct: 20  PPPSPGDRARVGTLQNKRVFLATFAAVLGN-FSFGYAL-VYTSP--VIPALERSLDPDLH 75

Query: 65  ATFMDGKLMLLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGV 124
            T           S   S+F LG   G L   +L D  GRK +++    F+ +P+   G 
Sbjct: 76  LTKSQA-------SWFGSVFTLGAAAGGLSAMILNDLLGRKLSIM----FSAVPSAA-GY 123

Query: 125 SKVAKAFEL--IVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFL 182
           + +A A  L  ++  R + G   G++ + +P+Y+ E+AP  +RG +G   ++  + G   
Sbjct: 124 ALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSL- 182

Query: 183 AQIFSLQAILGNPAGWPVLLALTG-VPALLQLLTLPFFPESPRYSLIQKGDEATARQALR 241
             +++L  +L  P  W   LA+ G  P L+ +L L F P SPR+ L+ +G +  A +AL 
Sbjct: 183 -SLYALGLLL--PWRW---LAVAGEAPVLIMILLLSFMPNSPRF-LLSRGRDEEALRALA 235

Query: 242 RLRGHTDMEAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINA 301
            LRG TD++   E  + +    R    +S     A    R   +++++ +  QQL+GI  
Sbjct: 236 WLRG-TDVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVCRPITVALLMRLL-QQLTGITP 293

Query: 302 INYYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSA 361
           I  Y  +I+ S  V         +  G V ++  + +A+ ++  GR+ LL          
Sbjct: 294 ILVYLQSIFDSTAVLLPPKDDAAI-VGAVRLLSVLIAALTMDLAGRKVLL---------- 342

Query: 362 CLVLTVVLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVD 421
                                      +++G+++G  P+  ++ +E+    +R  A  + 
Sbjct: 343 ---------------------------FVSGYAVGWGPITWLLMSEVLPLRARGVASGLC 375

Query: 422 GAVHWLTNFIIGFLFPSIQEAIG-AYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRI 480
               WLT F++   F  +    G    F  FA ICL++ ++    +PETKG++  +I   
Sbjct: 376 VLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESF 435

Query: 481 FAKRNR 486
           F    R
Sbjct: 436 FRTGRR 441


>gi|21553331 solute carrier family 2 (facilitated glucose
           transporter), member 12 [Homo sapiens]
          Length = 617

 Score =  121 bits (303), Expect = 2e-27
 Identities = 80/303 (26%), Positives = 159/303 (52%), Gaps = 13/303 (4%)

Query: 74  LLLWSC-----TVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVA 128
           LL  SC      VS   +G LL SL  G+L+D  GR+  +++++    + ++++ +S   
Sbjct: 71  LLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSL-- 128

Query: 129 KAFELIVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSL 188
            ++ +++  R+ +GV   +S  A  +Y+ E+AP++ RG++ ++ E+ +++G+  A I S 
Sbjct: 129 -SYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYI-SN 186

Query: 189 QAILGNPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTD 248
            A      GW  +  L     +LQ + + F P SPR+ L+ KG E  A + L RLR  +D
Sbjct: 187 YAFANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRF-LVMKGQEGAASKVLGRLRALSD 245

Query: 249 MEAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADT 308
              EL  +++  + E       +    +  ++R +++  + L+   Q++G   I +YA T
Sbjct: 246 TTEELTVIKSSLKDEYQYSFWDLFR--SKDNMRTRIMIGLTLVFFVQITGQPNILFYAST 303

Query: 309 IYTSAGVEAAH-SQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTV 367
           +  S G ++   +   + G GVV ++ TI + +LV+ +G +  L  G  +  ++ + + +
Sbjct: 304 VLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGI 363

Query: 368 VLL 370
           V L
Sbjct: 364 VNL 366



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 39/138 (28%), Positives = 70/138 (50%), Gaps = 6/138 (4%)

Query: 378 LSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFP 437
           L +L +  +  Y+A  SIG  P+P +V +EIF    R  A  +  +++W  N +I   F 
Sbjct: 460 LKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFL 519

Query: 438 SIQEAIG-AYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKRNRVK-----LPE 491
           ++ + IG  +   I+  + L + +++ + IPETKG +  +I+   AK N VK     +  
Sbjct: 520 TVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQISMELAKVNYVKNNICFMSH 579

Query: 492 EKEETIDAGPPTASPAKE 509
            +EE +   P    P ++
Sbjct: 580 HQEELVPKQPQKRKPQEQ 597



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 37/159 (23%), Positives = 68/159 (42%), Gaps = 16/159 (10%)

Query: 317 AAHSQYVTVGSGVVNIVM-TITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNRV 375
           + H Q + V S V+  ++ ++T  VL++R GRR  ++    + G   LVL         +
Sbjct: 75  SCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVL---------I 125

Query: 376 PELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFM----VDGAVHWLTNFI 431
             LSY  ++ V     G SI  S + + V         RR   +    +   +  L+ +I
Sbjct: 126 LSLSYT-VLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYI 184

Query: 432 IGFLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETK 470
             + F ++      Y F +   + +L AI +Y + P  +
Sbjct: 185 SNYAFANVFHG-WKYMFGLVIPLGVLQAIAMYFLPPSPR 222


>gi|13540547 solute carrier family 2 member 10 [Homo sapiens]
          Length = 541

 Score =  106 bits (265), Expect = 4e-23
 Identities = 101/359 (28%), Positives = 162/359 (45%), Gaps = 44/359 (12%)

Query: 21  PTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLMLLLWSCT 80
           P +L    S +      +GY L+V++      +  +  +  E+   F+ G L+L      
Sbjct: 5   PPVLPLCASVSLLGGLTFGYELAVISGALLPLQLDFGLSCLEQE--FLVGSLLL------ 56

Query: 81  VSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVV 140
                 G LL SL+ G L+D  GRK  +L +N+  +  ++ +G+   A +   +V  R V
Sbjct: 57  ------GALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGL---AGSLAWLVLGRAV 107

Query: 141 LGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPV 200
           +G    +S  A  +Y+ EL     RG++ ++ E  + VG+ L+   +  A+ G P GW  
Sbjct: 108 VGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNY-ALAGTPWGWRH 166

Query: 201 LLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMRAEA 260
           +      PA+LQ L+L F P           DE    + L  L+G             EA
Sbjct: 167 MFGWATAPAVLQSLSLLFLPAGT--------DETATHKDLIPLQG------------GEA 206

Query: 261 -RAERAEGHLSVLHLCALR-SLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAGVEAA 318
            +        S L L   R ++R +    + L+  QQL+G   +  YA TI++S G    
Sbjct: 207 PKLGPGRPRYSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGG 266

Query: 319 HSQYV-TVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNRVP 376
            S  + +VG G V +  T+T+  LV+R GRR LLLAG   C    L ++ + L    VP
Sbjct: 267 SSAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAG---CALMALSVSGIGLVSFAVP 322



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 32/108 (29%), Positives = 59/108 (54%), Gaps = 1/108 (0%)

Query: 378 LSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFP 437
           L +  ++C+  +++  S G  PV  +V +EI+    R  AF    + +W  N  I   F 
Sbjct: 408 LRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFL 467

Query: 438 SIQEAIG-AYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKR 484
            +   IG +++F+++    +L   +IY+ +PETKG++  EI++ F KR
Sbjct: 468 DLIGTIGLSWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQKR 515


>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
           sapiens]
          Length = 554

 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 105/437 (24%), Positives = 177/437 (40%), Gaps = 58/437 (13%)

Query: 87  GGLLGSLLVGLLVDSCGRK----GTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVVLG 142
           G L GSL VG   D  GRK    GT+L+N +  ++ A        +  +  ++  R++ G
Sbjct: 158 GFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAF-------SPNYMSMLLFRLLQG 210

Query: 143 VCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPVLL 202
           + +  ++ A    + E      R  V  M ++   VG     + +L  +      W  L 
Sbjct: 211 LVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVG-----LVALTGLAYALPHWRWLQ 265

Query: 203 ALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAEL--EDMRAEA 260
               +P  L LL     PESPR+ L QK +     +A++ +        +L   D++  +
Sbjct: 266 LAVSLPTFLFLLYYWCVPESPRWLLSQKRN----TEAIKIMDHIAQKNGKLPPADLKMLS 321

Query: 261 RAERAEGHLSVLHLCALRSLRWQLLSII---------VLMAGQQL-SGINAINYYADTIY 310
             E     LS       R+ R +  + I         VL  G  L  G  + N Y D +Y
Sbjct: 322 LEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVLYQGLILHMGATSGNLYLDFLY 381

Query: 311 TSAGVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLL 370
                           S +V I     + + ++R+GR + +     + G+ACLV+  +  
Sbjct: 382 ----------------SALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFI-- 423

Query: 371 FQNRVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNF 430
                P+L +L II +     G +I    +  +V  E++    R    MV  ++  +   
Sbjct: 424 ----SPDLHWLNIIIMCVGRMGITIAIQMI-CLVNAELYPTFVRNLGVMVCSSLCDIGGI 478

Query: 431 IIGFLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKRNRVKLP 490
           I  F+   ++E   A   I+FA + LL A  + +++PETKG    E  +      R   P
Sbjct: 479 ITPFIVFRLREVWQALPLILFAVLGLLAA-GVTLLLPETKGVALPETMKDAENLGRKAKP 537

Query: 491 EEKEETIDAGPPTASPA 507
             KE TI     T+ P+
Sbjct: 538 --KENTIYLKVQTSEPS 552


>gi|213021148 SVOP-like isoform 1 [Homo sapiens]
          Length = 492

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 87/418 (20%), Positives = 167/418 (39%), Gaps = 39/418 (9%)

Query: 82  SMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVVL 141
           +M   G ++ S+L GLL D  GR   LLI+ ++    ++L   +  A ++   VF R ++
Sbjct: 91  TMVFFGYMVFSILFGLLADRYGRWKILLISFLWGAYFSLL---TSFAPSYIWFVFLRTMV 147

Query: 142 GVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPVL 201
           G C    +S   +   E  P   RG +  +++VF + G  L  I  L +++    GW  L
Sbjct: 148 G-CGVSGHSQGLIIKTEFLPTKYRGYMLPLSQVFWLAGSLL--IIGLASVIIPTIGWRWL 204

Query: 202 LALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMRAEAR 261
           + +  +P ++ ++   F PES R++ +  G+   A   L R+    +     E    E  
Sbjct: 205 IRVASIPGIILIVAFKFIPESARFN-VSTGNTRAALATLERV-AKMNRSVMPEGKLVEPV 262

Query: 262 AERAEGHLSVLHLCALRS-----LRWQLLSI----IVLMAGQQLSGINAINYYADTIYTS 312
            E+      +L    LR+     + W  +S     ++L + + L         +D+    
Sbjct: 263 LEKRGRFADLLDAKYLRTTLQIWVIWLGISFAYYGVILASAELLERDLVCGSKSDSAVVV 322

Query: 313 AGVEAAHSQ------------YVT-VGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICG 359
            G ++  SQ            Y T + S +  I +   + + +  LGRR  L    G   
Sbjct: 323 TGGDSGESQSPCYCHMFAPSDYRTMIISTIGEIALNPLNILGINFLGRRLSLSITMGCTA 382

Query: 360 SACLVLTVVLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFM 419
              L+L +           S  G+I     +            +   E++  + R     
Sbjct: 383 LFFLLLNIC---------TSSAGLIGFLFMLRALVAANFNTVYIYTAEVYPTTMRALGMG 433

Query: 420 VDGAVHWLTNFIIGFLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEI 477
             G++  +   +  F+   +  A    +  +F+ +C++ AI  + +  ETKG+   +I
Sbjct: 434 TSGSLCRIGAMVAPFISQVLMSASILGALCLFSSVCVVCAISAFTLPIETKGRALQQI 491


>gi|170650643 solute carrier family 22, member 23 isoform a [Homo
           sapiens]
          Length = 686

 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 76/288 (26%), Positives = 126/288 (43%), Gaps = 29/288 (10%)

Query: 77  WSCTVSMFPL--GGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELI 134
           W   ++ F L  G + G L+ G + D  GR+  LL + IF +I  + + +S     F  +
Sbjct: 227 WKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTL 286

Query: 135 VFSRVVLGVC-AGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILG 193
            F     G C AGI  +   + + EL P   R M+  +     + G FL     L A+  
Sbjct: 287 RFFE---GFCLAGIILTLYALRI-ELCPPGKRFMITMVASFVAMAGQFLMP--GLAALCR 340

Query: 194 NPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQAL-----RRLRGHTD 248
           +   W VL AL   P LL LL    FPES R+ +  +  E+  R  L      R+    D
Sbjct: 341 D---WQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGD 397

Query: 249 MEAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADT 308
           ++  + ++  E    R    + ++ +   R+L W+    IV++    L+G    + +A +
Sbjct: 398 IKGVIPEL--EKELSRRPKKVCIVKVVGTRNL-WK---NIVVLCVNSLTGYGIHHCFARS 451

Query: 309 IYTSAG----VEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLL 352
           +         +E  ++ Y T  S  + +V  +   V+V  LGRR  LL
Sbjct: 452 MMGHEVKVPLLENFYADYYTTAS--IALVSCLAMCVVVRFLGRRGGLL 497


>gi|4507001 solute carrier family 22 member 2 [Homo sapiens]
          Length = 555

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 92/430 (21%), Positives = 168/430 (39%), Gaps = 45/430 (10%)

Query: 73  MLLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFE 132
           ML L+  +V++   G  +GS+ +G + D  GRK  LL   +      +LM +S     + 
Sbjct: 148 MLDLFQSSVNV---GFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMAIS---PTYT 201

Query: 133 LIVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAIL 192
            ++  R++ G+ +   +    + + E   +  R  VG   +V   VG+ +     L  + 
Sbjct: 202 WMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVGIFYQVAYTVGLLV-----LAGVA 256

Query: 193 GNPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRL--RGHTDME 250
                W  L     +P    LL     PESPR+ LI +   A A + ++ +  +    + 
Sbjct: 257 YALPHWRWLQFTVALPNFFFLLYYWCIPESPRW-LISQNKNAEAMRIIKHIAKKNGKSLP 315

Query: 251 AELEDMRAEARAERA--EGHLSVLHLCALRS----LRWQLLSIIVLMAGQQL-SGINAIN 303
           A L+ +R E    +      L ++    +R     L +   +  VL  G  +  G+   N
Sbjct: 316 ASLQRLRLEEETGKKLNPSFLDLVRTPQIRKHTMILMYNWFTSSVLYQGLIMHMGLAGDN 375

Query: 304 YYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACL 363
            Y D  Y                S +V         + ++R+GRR+   A   + G+ACL
Sbjct: 376 IYLDFFY----------------SALVEFPAAFMIILTIDRIGRRYPWAASNMVAGAACL 419

Query: 364 VLTVVLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGA 423
               +        +L +L II       G ++    +  +V  E++    R     +  +
Sbjct: 420 ASVFI------PGDLQWLKIIISCLGRMGITMA-YEIVCLVNAELYPTFIRNLGVHICSS 472

Query: 424 VHWLTNFIIGFLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAK 483
           +  +   I  FL   +         ++F G+  L A  + +++PETKGK   E       
Sbjct: 473 MCDIGGIITPFLVYRLTNIWLELPLMVF-GVLGLVAGGLVLLLPETKGKALPETIEEAEN 531

Query: 484 RNRVKLPEEK 493
             R +  +EK
Sbjct: 532 MQRPRKNKEK 541


>gi|4507005 solute carrier family 22 member 5 [Homo sapiens]
          Length = 557

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 99/411 (24%), Positives = 178/411 (43%), Gaps = 60/411 (14%)

Query: 80  TVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKV---AKAFELIVF 136
           T+S+F +G LLGS + G L D  GRK      N+  +   +  G S +   +K FE+ V 
Sbjct: 145 TISLFFVGVLLGSFISGQLSDRFGRK------NVLFVTMGMQTGFSFLQIFSKNFEMFVV 198

Query: 137 SRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTM-TEVFVIVGVFLAQIFSLQAILGNP 195
             V++G+    +Y A  +   E+  K++R +  T+   +F   G  +  +F+        
Sbjct: 199 LFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAFGYMVLPLFAYFI----- 253

Query: 196 AGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDM------ 249
             W +LL    +P +L +    F PESPR+ LI +G    A   +R+      +      
Sbjct: 254 RDWRMLLVALTMPGVLCVALWWFIPESPRW-LISQGRFEEAEVIIRKAAKANGIVVPSTI 312

Query: 250 --EAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYAD 307
              +EL+D+     +++ + H ++L L  LR+   ++++I+ +M    +S    + Y+  
Sbjct: 313 FDPSELQDL----SSKKQQSH-NILDL--LRTWNIRMVTIMSIMLWMTIS----VGYFG- 360

Query: 308 TIYTSAGVEAAHSQYVT--VGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVL 365
               S      H         S +V +   + + +L++ L RR+ +     + GS     
Sbjct: 361 ---LSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGS----- 412

Query: 366 TVVLLFQNRV-PELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAV 424
             VLLF   V P+L YL  + V     G +   S V  V   E++    R     V    
Sbjct: 413 --VLLFMQLVPPDLYYLATVLVMVGKFGVTAAFSMV-YVYTAELYPTVVRNMGVGVSSTA 469

Query: 425 HWLTNFIIGFLFPSIQEAIGAYS----FIIFAGICLLTAIYIYVVIPETKG 471
             L + +  +        +GAY     +I+   + +LTAI + + +PE+ G
Sbjct: 470 SRLGSILSPYFV-----YLGAYDRFLPYILMGSLTILTAI-LTLFLPESFG 514


>gi|11415038 solute carrier family 22 member 3 [Homo sapiens]
          Length = 556

 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 113/484 (23%), Positives = 183/484 (37%), Gaps = 56/484 (11%)

Query: 6   AGTPPPIPSREGRLQPTLL-LATLSAAFGSAFQYGYNLSVV-NTPHKVFKSFYNETYFER 63
           A   P  P R GR Q  LL  A  SA+  SA      L+   N    +        Y + 
Sbjct: 77  ASRGPEPPERRGRCQRYLLEAANDSASATSALSCADPLAAFPNRSAPLVPCRGGWRYAQA 136

Query: 64  HATFMDGKLMLLL--W--SCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPA 119
           H+T +    ++ +  W    T ++  LG L G+  +G   D  GR    L++ +   +  
Sbjct: 137 HSTIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADRYGRIVIYLLSCLGVGVTG 196

Query: 120 ILMGVSKVAKAFELIVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVG 179
           +++     A  F + V  R + GV    ++    + + E+     R +VG + ++F  +G
Sbjct: 197 VVVAF---APNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLG 253

Query: 180 VFLAQIFSLQAILGNPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLI-QKGDEATARQ 238
           + +     +   + N  G  + LA+T +P+ L LL     PESPR+ +  +KGD+A   Q
Sbjct: 254 IIILP--GIAYFIPNWQG--IQLAIT-LPSFLFLLYYWVVPESPRWLITRKKGDKAL--Q 306

Query: 239 ALRRLR-------GHTDMEAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLM 291
            LRR+             E  + D      +         +  C L  +     S +V  
Sbjct: 307 ILRRIAKCNGKYLSSNYSEITVTDEEVSNPSFLDLVRTPQMRKCTLILMFAWFTSAVVYQ 366

Query: 292 AGQQLSGINAINYYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLL 351
                 GI   N Y D                   SGVV +   +   + +ERLGRR   
Sbjct: 367 GLVMRLGIIGGNLYIDFFI----------------SGVVELPGALLILLTIERLGRRLPF 410

Query: 352 LAGYGICGSACLVLTV----VLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTE 407
            A   + G ACLV       +   +  V  L  LGI   F  +            +V +E
Sbjct: 411 AASNIVAGVACLVTAFLPEGIAWLRTTVATLGRLGITMAFEIV-----------YLVNSE 459

Query: 408 IFLQSSRRAAFMVDGAVHWLTNFIIGFLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIP 467
           ++  + R     +   +      I  FL   +         IIF GI       + +++P
Sbjct: 460 LYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAVWLELPLIIF-GILASICGGLVMLLP 518

Query: 468 ETKG 471
           ETKG
Sbjct: 519 ETKG 522


>gi|24497480 solute carrier family 22 member 6 isoform d [Homo
           sapiens]
          Length = 519

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 78/315 (24%), Positives = 132/315 (41%), Gaps = 25/315 (7%)

Query: 82  SMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVVL 141
           S++ +G LLG+++ G L D  GR+  L++N +     A+    +  A  F +    R++ 
Sbjct: 139 SLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQT---AVSGTCAAFAPNFPIYCAFRLLS 195

Query: 142 GVC-AGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPV 200
           G+  AGIS + + + + E  P + R  VGT+      +G FL     L  +      W  
Sbjct: 196 GMALAGISLNCMTLNV-EWMPIHTRACVGTLIGYVYSLGQFL-----LAGVAYAVPHWRH 249

Query: 201 LLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATAR--QALRRLRGHTDMEAEL--EDM 256
           L  L   P     +   FF ES R+       + T R  Q + R+ G  +  A+L  E +
Sbjct: 250 LQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVL 309

Query: 257 RAEARAE--RAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAG 314
           RA  + E    +G  S + L    +LR   L + +L      +       Y   +    G
Sbjct: 310 RASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFA-------YYGLVMDLQG 362

Query: 315 VEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNR 374
                   + V  G V++   +   +++  LGRR   +A   + G   L+  V+   Q+ 
Sbjct: 363 F-GVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSI 421

Query: 375 V-PELSYLGIICVFA 388
           V   L+ LG  C+ A
Sbjct: 422 VRTSLAVLGKGCLAA 436


>gi|24497478 solute carrier family 22 member 6 isoform c [Homo
           sapiens]
          Length = 506

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 78/315 (24%), Positives = 132/315 (41%), Gaps = 25/315 (7%)

Query: 82  SMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVVL 141
           S++ +G LLG+++ G L D  GR+  L++N +     A+    +  A  F +    R++ 
Sbjct: 139 SLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQT---AVSGTCAAFAPNFPIYCAFRLLS 195

Query: 142 GVC-AGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPV 200
           G+  AGIS + + + + E  P + R  VGT+      +G FL     L  +      W  
Sbjct: 196 GMALAGISLNCMTLNV-EWMPIHTRACVGTLIGYVYSLGQFL-----LAGVAYAVPHWRH 249

Query: 201 LLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATAR--QALRRLRGHTDMEAEL--EDM 256
           L  L   P     +   FF ES R+       + T R  Q + R+ G  +  A+L  E +
Sbjct: 250 LQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVL 309

Query: 257 RAEARAE--RAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAG 314
           RA  + E    +G  S + L    +LR   L + +L      +       Y   +    G
Sbjct: 310 RASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFA-------YYGLVMDLQG 362

Query: 315 VEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNR 374
                   + V  G V++   +   +++  LGRR   +A   + G   L+  V+   Q+ 
Sbjct: 363 F-GVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSI 421

Query: 375 V-PELSYLGIICVFA 388
           V   L+ LG  C+ A
Sbjct: 422 VRTSLAVLGKGCLAA 436


>gi|24497476 solute carrier family 22 member 6 isoform b [Homo
           sapiens]
          Length = 550

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 78/315 (24%), Positives = 132/315 (41%), Gaps = 25/315 (7%)

Query: 82  SMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVVL 141
           S++ +G LLG+++ G L D  GR+  L++N +     A+    +  A  F +    R++ 
Sbjct: 139 SLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQT---AVSGTCAAFAPNFPIYCAFRLLS 195

Query: 142 GVC-AGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPV 200
           G+  AGIS + + + + E  P + R  VGT+      +G FL     L  +      W  
Sbjct: 196 GMALAGISLNCMTLNV-EWMPIHTRACVGTLIGYVYSLGQFL-----LAGVAYAVPHWRH 249

Query: 201 LLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATAR--QALRRLRGHTDMEAEL--EDM 256
           L  L   P     +   FF ES R+       + T R  Q + R+ G  +  A+L  E +
Sbjct: 250 LQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVL 309

Query: 257 RAEARAE--RAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAG 314
           RA  + E    +G  S + L    +LR   L + +L      +       Y   +    G
Sbjct: 310 RASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFA-------YYGLVMDLQG 362

Query: 315 VEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNR 374
                   + V  G V++   +   +++  LGRR   +A   + G   L+  V+   Q+ 
Sbjct: 363 F-GVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSI 421

Query: 375 V-PELSYLGIICVFA 388
           V   L+ LG  C+ A
Sbjct: 422 VRTSLAVLGKGCLAA 436


>gi|20070188 solute carrier family 22 member 6 isoform a [Homo
           sapiens]
          Length = 563

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 78/315 (24%), Positives = 132/315 (41%), Gaps = 25/315 (7%)

Query: 82  SMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVVL 141
           S++ +G LLG+++ G L D  GR+  L++N +     A+    +  A  F +    R++ 
Sbjct: 139 SLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQT---AVSGTCAAFAPNFPIYCAFRLLS 195

Query: 142 GVC-AGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPV 200
           G+  AGIS + + + + E  P + R  VGT+      +G FL     L  +      W  
Sbjct: 196 GMALAGISLNCMTLNV-EWMPIHTRACVGTLIGYVYSLGQFL-----LAGVAYAVPHWRH 249

Query: 201 LLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATAR--QALRRLRGHTDMEAEL--EDM 256
           L  L   P     +   FF ES R+       + T R  Q + R+ G  +  A+L  E +
Sbjct: 250 LQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVL 309

Query: 257 RAEARAE--RAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAG 314
           RA  + E    +G  S + L    +LR   L + +L      +       Y   +    G
Sbjct: 310 RASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFA-------YYGLVMDLQG 362

Query: 315 VEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNR 374
                   + V  G V++   +   +++  LGRR   +A   + G   L+  V+   Q+ 
Sbjct: 363 F-GVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSI 421

Query: 375 V-PELSYLGIICVFA 388
           V   L+ LG  C+ A
Sbjct: 422 VRTSLAVLGKGCLAA 436


>gi|24308167 SV2 related protein [Homo sapiens]
          Length = 548

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 91/411 (22%), Positives = 167/411 (40%), Gaps = 42/411 (10%)

Query: 86  LGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVVLGVCA 145
           +G +  S L G + D  GRK  L I+ ++ +   IL   S  A  +  I+  R ++G   
Sbjct: 131 VGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGIL---SAFAPVYSWILVLRGLVGFGI 187

Query: 146 GISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPA-GWPVLLAL 204
           G    ++ +Y  E  P   R     + EVF  +G     +    A+   P+ GW  LL L
Sbjct: 188 GGVPQSVTLY-AEFLPMKARAKCILLIEVFWAIGTVFEVVL---AVFVMPSLGWRWLLIL 243

Query: 205 TGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMRAEARAER 264
           + VP LL  +   + PES RY ++  G++  A   L+R+         L  +    + +R
Sbjct: 244 SAVPLLLFAVLCFWLPESARYDVL-SGNQEKAIATLKRIATENGAPMPLGKLIISRQEDR 302

Query: 265 AE-GHLSVLHLCALRSLRW-------------QLLSIIVLMAGQQLSGINAINYYADTIY 310
            +   L   H      L W              LL+  +  AG  + GI++     +   
Sbjct: 303 GKMRDLFTPHFRWTTLLLWFIWFSNAFSYYGLVLLTTELFQAG-DVCGISSRKKAVEAKC 361

Query: 311 TSAGVEAAHSQYV----TVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLT 366
           + A    +   Y+    T  S    +++T+    +++RLGR+  +   + +  S C +L 
Sbjct: 362 SLACEYLSEEDYMDLLWTTLSEFPGVLVTLW---IIDRLGRKKTMALCF-VIFSFCSLLL 417

Query: 367 VVLLFQNRVPELSYLGIICVFAYIAGHSI-GPSPVPSVVRTEIFLQSSRRAAFMVDGAVH 425
            + + +N         ++ +  +IA   I G      V   E++  ++R         + 
Sbjct: 418 FICVGRN---------VLTLLLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMA 468

Query: 426 WLTNFIIGFLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVE 476
            +   I  F+   + E+    +  +++G CLL A+    +  ETKG+   E
Sbjct: 469 RVGALITPFIAQVMLESSVYLTLAVYSGCCLLAALASCFLPIETKGRGLQE 519


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.140    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,154,506
Number of Sequences: 37866
Number of extensions: 766930
Number of successful extensions: 2984
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 2857
Number of HSP's gapped (non-prelim): 94
length of query: 512
length of database: 18,247,518
effective HSP length: 107
effective length of query: 405
effective length of database: 14,195,856
effective search space: 5749321680
effective search space used: 5749321680
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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