Search of human proteins with 133778974

Search of human proteins with 133778974

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|133778974 transketolase-like 2 [Homo sapiens]
         (626 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|133778974 transketolase-like 2 [Homo sapiens]                     1251   0.0  
gi|225637459 transketolase-like 1 isoform a [Homo sapiens]            892   0.0  
gi|225637461 transketolase-like 1 isoform b [Homo sapiens]            880   0.0  
gi|205277463 transketolase isoform 1 [Homo sapiens]                   851   0.0  
gi|4507521 transketolase isoform 1 [Homo sapiens]                     851   0.0  
gi|225637463 transketolase-like 1 isoform c [Homo sapiens]            837   0.0  
gi|205277465 transketolase isoform 2 [Homo sapiens]                   663   0.0  
gi|156564403 pyruvate dehydrogenase (lipoamide) beta [Homo sapiens]    58   2e-08
gi|4557353 branched chain keto acid dehydrogenase E1 beta precur...    54   6e-07
gi|34101272 branched chain keto acid dehydrogenase E1 beta precu...    54   6e-07
gi|11386135 branched chain keto acid dehydrogenase E1, alpha pol...    39   0.019
gi|52317186 olfactory receptor, family 13, subfamily D, member 1...    31   3.9  
gi|41054864 regulating synaptic membrane exocytosis 1 [Homo sapi...    30   5.1  
gi|4505685 pyruvate dehydrogenase E1 alpha 1 precursor [Homo sap...    30   6.7  

>gi|133778974 transketolase-like 2 [Homo sapiens]
          Length = 626

 Score = 1251 bits (3238), Expect = 0.0
 Identities = 626/626 (100%), Positives = 626/626 (100%)

Query: 1   MMANDAKPDVKTVQVLRDTANRLRIHSIRATCASGSGQLTSCCSAAEVVSVLFFHTMKYK 60
           MMANDAKPDVKTVQVLRDTANRLRIHSIRATCASGSGQLTSCCSAAEVVSVLFFHTMKYK
Sbjct: 1   MMANDAKPDVKTVQVLRDTANRLRIHSIRATCASGSGQLTSCCSAAEVVSVLFFHTMKYK 60

Query: 61  QTDPEHPDNDRFILSRGHAAPILYAAWVEVGDISESDLLNLRKLHSDLERHPTPRLPFVD 120
           QTDPEHPDNDRFILSRGHAAPILYAAWVEVGDISESDLLNLRKLHSDLERHPTPRLPFVD
Sbjct: 61  QTDPEHPDNDRFILSRGHAAPILYAAWVEVGDISESDLLNLRKLHSDLERHPTPRLPFVD 120

Query: 121 VATGSLGQGLGTACGMAYTGKYLDKASYRVFCLMGDGESSEGSVWEAFAFASHYNLDNLV 180
           VATGSLGQGLGTACGMAYTGKYLDKASYRVFCLMGDGESSEGSVWEAFAFASHYNLDNLV
Sbjct: 121 VATGSLGQGLGTACGMAYTGKYLDKASYRVFCLMGDGESSEGSVWEAFAFASHYNLDNLV 180

Query: 181 AVFDVNRLGQSGPAPLEHGADIYQNCCEAFGWNTYLVDGHDVEALCQAFWQASQVKNKPT 240
           AVFDVNRLGQSGPAPLEHGADIYQNCCEAFGWNTYLVDGHDVEALCQAFWQASQVKNKPT
Sbjct: 181 AVFDVNRLGQSGPAPLEHGADIYQNCCEAFGWNTYLVDGHDVEALCQAFWQASQVKNKPT 240

Query: 241 AIVAKTFKGRGIPNIEDAENWHGKPVPKERADAIVKLIESQIQTNENLIPKSPVEDSPQI 300
           AIVAKTFKGRGIPNIEDAENWHGKPVPKERADAIVKLIESQIQTNENLIPKSPVEDSPQI
Sbjct: 241 AIVAKTFKGRGIPNIEDAENWHGKPVPKERADAIVKLIESQIQTNENLIPKSPVEDSPQI 300

Query: 301 SITDIKMTSPPAYKVGDKIATQKTYGLALAKLGRANERVIVLSGDTMNSTFSEIFRKEHP 360
           SITDIKMTSPPAYKVGDKIATQKTYGLALAKLGRANERVIVLSGDTMNSTFSEIFRKEHP
Sbjct: 301 SITDIKMTSPPAYKVGDKIATQKTYGLALAKLGRANERVIVLSGDTMNSTFSEIFRKEHP 360

Query: 361 ERFIECIIAEQNMVSVALGCATRGRTIAFAGAFAAFFTRAFDQLRMGAISQANINLIGSH 420
           ERFIECIIAEQNMVSVALGCATRGRTIAFAGAFAAFFTRAFDQLRMGAISQANINLIGSH
Sbjct: 361 ERFIECIIAEQNMVSVALGCATRGRTIAFAGAFAAFFTRAFDQLRMGAISQANINLIGSH 420

Query: 421 CGVSTGEDGVSQMALEDLAMFRSIPNCTVFYPSDAISTEHAIYLAANTKGMCFIRTSQPE 480
           CGVSTGEDGVSQMALEDLAMFRSIPNCTVFYPSDAISTEHAIYLAANTKGMCFIRTSQPE
Sbjct: 421 CGVSTGEDGVSQMALEDLAMFRSIPNCTVFYPSDAISTEHAIYLAANTKGMCFIRTSQPE 480

Query: 481 TAVIYTPQENFEIGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLSQQGISVRVIDPFT 540
           TAVIYTPQENFEIGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLSQQGISVRVIDPFT
Sbjct: 481 TAVIYTPQENFEIGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLSQQGISVRVIDPFT 540

Query: 541 IKPLDAATIISSAKATGGRVITVEDHYREGGIGEAVCAAVSREPDILVHQLAVSGVPQRG 600
           IKPLDAATIISSAKATGGRVITVEDHYREGGIGEAVCAAVSREPDILVHQLAVSGVPQRG
Sbjct: 541 IKPLDAATIISSAKATGGRVITVEDHYREGGIGEAVCAAVSREPDILVHQLAVSGVPQRG 600

Query: 601 KTSELLDMFGISTRHIIAAVTLTLMK 626
           KTSELLDMFGISTRHIIAAVTLTLMK
Sbjct: 601 KTSELLDMFGISTRHIIAAVTLTLMK 626


>gi|225637459 transketolase-like 1 isoform a [Homo sapiens]
          Length = 596

 Score =  892 bits (2304), Expect = 0.0
 Identities = 438/621 (70%), Positives = 513/621 (82%), Gaps = 38/621 (6%)

Query: 5   DAKPDVKTVQVLRDTANRLRIHSIRATCASGSGQLTSCCSAAEVVSVLFFHTMKYKQTDP 64
           +A+PD  T+QVL+D A+RLRIHSIRATC++ SG  TSC S++E++SVLFF+ M+YKQ+DP
Sbjct: 13  EARPDRGTLQVLQDMASRLRIHSIRATCSTSSGHPTSCSSSSEIMSVLFFYIMRYKQSDP 72

Query: 65  EHPDNDRFILSRGHAAPILYAAWVEVGDISESDLLNLRKLHSDLERHPTPRLPFVDVATG 124
           E+PDNDRF+L++                                      RL FVDVATG
Sbjct: 73  ENPDNDRFVLAK--------------------------------------RLSFVDVATG 94

Query: 125 SLGQGLGTACGMAYTGKYLDKASYRVFCLMGDGESSEGSVWEAFAFASHYNLDNLVAVFD 184
            LGQGLG ACGMAYTGKY D+ASYRVFCLM DGESSEGSVWEA AFAS+Y+LDNLVA+FD
Sbjct: 95  WLGQGLGVACGMAYTGKYFDRASYRVFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFD 154

Query: 185 VNRLGQSGPAPLEHGADIYQNCCEAFGWNTYLVDGHDVEALCQAFWQASQVKNKPTAIVA 244
           VNRLG SG  P EH  +IYQ  CEAFGWNTY+VDG DVEALCQ FWQASQVK+KPTA+VA
Sbjct: 155 VNRLGHSGALPAEHCINIYQRRCEAFGWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVA 214

Query: 245 KTFKGRGIPNIEDAENWHGKPVPKERADAIVKLIESQIQTNENLIPKSPVEDSPQISITD 304
           KTFKGRG P+IEDAE+WH KP+P+ERADAI+KLIESQIQT+ NL P+ P+EDSP+++ITD
Sbjct: 215 KTFKGRGTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITD 274

Query: 305 IKMTSPPAYKVGDKIATQKTYGLALAKLGRANERVIVLSGDTMNSTFSEIFRKEHPERFI 364
           ++MTSPP Y+VGDKIAT+K  GLALAKLG AN RV+VL GDT  STFSEIF KE+PERFI
Sbjct: 275 VRMTSPPDYRVGDKIATRKACGLALAKLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFI 334

Query: 365 ECIIAEQNMVSVALGCATRGRTIAFAGAFAAFFTRAFDQLRMGAISQANINLIGSHCGVS 424
           EC +AEQNMVSVALGCA+RGRTIAFA  FAAF TRAFD +R+G ++++NIN+IGSHCGVS
Sbjct: 335 ECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHIRIGGLAESNINIIGSHCGVS 394

Query: 425 TGEDGVSQMALEDLAMFRSIPNCTVFYPSDAISTEHAIYLAANTKGMCFIRTSQPETAVI 484
            G+DG SQMALED+AMFR+IP CT+FYP+DA+STEHA+ LAAN KGMCFIRT++PET VI
Sbjct: 395 VGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAANAKGMCFIRTTRPETMVI 454

Query: 485 YTPQENFEIGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLSQQGISVRVIDPFTIKPL 544
           YTPQE FEIGQAKV+RH V+DKVTVIGAG+T++EAL AAD LS+Q I +RVID FTIKPL
Sbjct: 455 YTPQERFEIGQAKVLRHCVSDKVTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPL 514

Query: 545 DAATIISSAKATGGRVITVEDHYREGGIGEAVCAAVSREPDILVHQLAVSGVPQRGKTSE 604
           D ATI+SSAKAT GR+ITVEDHY +GGIGEAVCAAVS +PDI VH LAVSGVPQ GK+ E
Sbjct: 515 DVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEE 574

Query: 605 LLDMFGISTRHIIAAVTLTLM 625
           LLDM+GIS RHII AV   L+
Sbjct: 575 LLDMYGISARHIIVAVKCMLL 595


>gi|225637461 transketolase-like 1 isoform b [Homo sapiens]
          Length = 590

 Score =  880 bits (2273), Expect = 0.0
 Identities = 435/621 (70%), Positives = 510/621 (82%), Gaps = 44/621 (7%)

Query: 5   DAKPDVKTVQVLRDTANRLRIHSIRATCASGSGQLTSCCSAAEVVSVLFFHTMKYKQTDP 64
           +A+PD  T+QVL+D A+RLRIHSIRATC++ SG      S++E++SVLFF+ M+YKQ+DP
Sbjct: 13  EARPDRGTLQVLQDMASRLRIHSIRATCSTSSG------SSSEIMSVLFFYIMRYKQSDP 66

Query: 65  EHPDNDRFILSRGHAAPILYAAWVEVGDISESDLLNLRKLHSDLERHPTPRLPFVDVATG 124
           E+PDNDRF+L++                                      RL FVDVATG
Sbjct: 67  ENPDNDRFVLAK--------------------------------------RLSFVDVATG 88

Query: 125 SLGQGLGTACGMAYTGKYLDKASYRVFCLMGDGESSEGSVWEAFAFASHYNLDNLVAVFD 184
            LGQGLG ACGMAYTGKY D+ASYRVFCLM DGESSEGSVWEA AFAS+Y+LDNLVA+FD
Sbjct: 89  WLGQGLGVACGMAYTGKYFDRASYRVFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFD 148

Query: 185 VNRLGQSGPAPLEHGADIYQNCCEAFGWNTYLVDGHDVEALCQAFWQASQVKNKPTAIVA 244
           VNRLG SG  P EH  +IYQ  CEAFGWNTY+VDG DVEALCQ FWQASQVK+KPTA+VA
Sbjct: 149 VNRLGHSGALPAEHCINIYQRRCEAFGWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVA 208

Query: 245 KTFKGRGIPNIEDAENWHGKPVPKERADAIVKLIESQIQTNENLIPKSPVEDSPQISITD 304
           KTFKGRG P+IEDAE+WH KP+P+ERADAI+KLIESQIQT+ NL P+ P+EDSP+++ITD
Sbjct: 209 KTFKGRGTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITD 268

Query: 305 IKMTSPPAYKVGDKIATQKTYGLALAKLGRANERVIVLSGDTMNSTFSEIFRKEHPERFI 364
           ++MTSPP Y+VGDKIAT+K  GLALAKLG AN RV+VL GDT  STFSEIF KE+PERFI
Sbjct: 269 VRMTSPPDYRVGDKIATRKACGLALAKLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFI 328

Query: 365 ECIIAEQNMVSVALGCATRGRTIAFAGAFAAFFTRAFDQLRMGAISQANINLIGSHCGVS 424
           EC +AEQNMVSVALGCA+RGRTIAFA  FAAF TRAFD +R+G ++++NIN+IGSHCGVS
Sbjct: 329 ECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHIRIGGLAESNINIIGSHCGVS 388

Query: 425 TGEDGVSQMALEDLAMFRSIPNCTVFYPSDAISTEHAIYLAANTKGMCFIRTSQPETAVI 484
            G+DG SQMALED+AMFR+IP CT+FYP+DA+STEHA+ LAAN KGMCFIRT++PET VI
Sbjct: 389 VGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAANAKGMCFIRTTRPETMVI 448

Query: 485 YTPQENFEIGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLSQQGISVRVIDPFTIKPL 544
           YTPQE FEIGQAKV+RH V+DKVTVIGAG+T++EAL AAD LS+Q I +RVID FTIKPL
Sbjct: 449 YTPQERFEIGQAKVLRHCVSDKVTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPL 508

Query: 545 DAATIISSAKATGGRVITVEDHYREGGIGEAVCAAVSREPDILVHQLAVSGVPQRGKTSE 604
           D ATI+SSAKAT GR+ITVEDHY +GGIGEAVCAAVS +PDI VH LAVSGVPQ GK+ E
Sbjct: 509 DVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEE 568

Query: 605 LLDMFGISTRHIIAAVTLTLM 625
           LLDM+GIS RHII AV   L+
Sbjct: 569 LLDMYGISARHIIVAVKCMLL 589


>gi|205277463 transketolase isoform 1 [Homo sapiens]
          Length = 623

 Score =  851 bits (2199), Expect = 0.0
 Identities = 415/614 (67%), Positives = 498/614 (81%), Gaps = 3/614 (0%)

Query: 7   KPDVKTVQVLRDTANRLRIHSIRATCASGSGQLTSCCSAAEVVSVLFFHTMKYKQTDPEH 66
           KPD + +Q L+DTANRLRI SI+AT A+GSG  TSCCSAAE+++VLFFHTM+YK  DP +
Sbjct: 6   KPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRN 65

Query: 67  PDNDRFILSRGHAAPILYAAWVEVGDISESDLLNLRKLHSDLERHPTPRLPFVDVATGSL 126
           P NDRF+LS+GHAAPILYA W E G ++E++LLNLRK+ SDL+ HP P+  F DVATGSL
Sbjct: 66  PHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDVATGSL 125

Query: 127 GQGLGTACGMAYTGKYLDKASYRVFCLMGDGESSEGSVWEAFAFASHYNLDNLVAVFDVN 186
           GQGLG ACGMAYTGKY DKASYRV+CL+GDGE SEGSVWEA AFAS Y LDNLVA+ D+N
Sbjct: 126 GQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDIN 185

Query: 187 RLGQSGPAPLEHGADIYQNCCEAFGWNTYLVDGHDVEALCQAFWQASQVKNKPTAIVAKT 246
           RLGQS PAPL+H  DIYQ  CEAFGW+  +VDGH VE LC+AF QA   K++PTAI+AKT
Sbjct: 186 RLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQA---KHQPTAIIAKT 242

Query: 247 FKGRGIPNIEDAENWHGKPVPKERADAIVKLIESQIQTNENLIPKSPVEDSPQISITDIK 306
           FKGRGI  +ED E+WHGKP+PK  A+ I++ I SQIQ+ + ++   P ED+P + I +I+
Sbjct: 243 FKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIR 302

Query: 307 MTSPPAYKVGDKIATQKTYGLALAKLGRANERVIVLSGDTMNSTFSEIFRKEHPERFIEC 366
           M S P+YKVGDKIAT+K YG ALAKLG A++R+I L GDT NSTFSEIF+KEHP+RFIEC
Sbjct: 303 MPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIEC 362

Query: 367 IIAEQNMVSVALGCATRGRTIAFAGAFAAFFTRAFDQLRMGAISQANINLIGSHCGVSTG 426
            IAEQNMVS+A+GCATR RT+ F   FAAFFTRAFDQ+RM AIS++NINL GSHCGVS G
Sbjct: 363 YIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIG 422

Query: 427 EDGVSQMALEDLAMFRSIPNCTVFYPSDAISTEHAIYLAANTKGMCFIRTSQPETAVIYT 486
           EDG SQMALEDLAMFRS+P  TVFYPSD ++TE A+ LAANTKG+CFIRTS+PE A+IY 
Sbjct: 423 EDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYN 482

Query: 487 PQENFEIGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLSQQGISVRVIDPFTIKPLDA 546
             E+F++GQAKVV    +D+VTVIGAGVTLHEAL AA+ L ++ I++RV+DPFTIKPLD 
Sbjct: 483 NNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDR 542

Query: 547 ATIISSAKATGGRVITVEDHYREGGIGEAVCAAVSREPDILVHQLAVSGVPQRGKTSELL 606
             I+ SA+AT GR++TVEDHY EGGIGEAV +AV  EP I V  LAV+ VP+ GK +ELL
Sbjct: 543 KLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELL 602

Query: 607 DMFGISTRHIIAAV 620
            MFGI    I  AV
Sbjct: 603 KMFGIDRDAIAQAV 616


>gi|4507521 transketolase isoform 1 [Homo sapiens]
          Length = 623

 Score =  851 bits (2199), Expect = 0.0
 Identities = 415/614 (67%), Positives = 498/614 (81%), Gaps = 3/614 (0%)

Query: 7   KPDVKTVQVLRDTANRLRIHSIRATCASGSGQLTSCCSAAEVVSVLFFHTMKYKQTDPEH 66
           KPD + +Q L+DTANRLRI SI+AT A+GSG  TSCCSAAE+++VLFFHTM+YK  DP +
Sbjct: 6   KPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRN 65

Query: 67  PDNDRFILSRGHAAPILYAAWVEVGDISESDLLNLRKLHSDLERHPTPRLPFVDVATGSL 126
           P NDRF+LS+GHAAPILYA W E G ++E++LLNLRK+ SDL+ HP P+  F DVATGSL
Sbjct: 66  PHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDVATGSL 125

Query: 127 GQGLGTACGMAYTGKYLDKASYRVFCLMGDGESSEGSVWEAFAFASHYNLDNLVAVFDVN 186
           GQGLG ACGMAYTGKY DKASYRV+CL+GDGE SEGSVWEA AFAS Y LDNLVA+ D+N
Sbjct: 126 GQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDIN 185

Query: 187 RLGQSGPAPLEHGADIYQNCCEAFGWNTYLVDGHDVEALCQAFWQASQVKNKPTAIVAKT 246
           RLGQS PAPL+H  DIYQ  CEAFGW+  +VDGH VE LC+AF QA   K++PTAI+AKT
Sbjct: 186 RLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQA---KHQPTAIIAKT 242

Query: 247 FKGRGIPNIEDAENWHGKPVPKERADAIVKLIESQIQTNENLIPKSPVEDSPQISITDIK 306
           FKGRGI  +ED E+WHGKP+PK  A+ I++ I SQIQ+ + ++   P ED+P + I +I+
Sbjct: 243 FKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIR 302

Query: 307 MTSPPAYKVGDKIATQKTYGLALAKLGRANERVIVLSGDTMNSTFSEIFRKEHPERFIEC 366
           M S P+YKVGDKIAT+K YG ALAKLG A++R+I L GDT NSTFSEIF+KEHP+RFIEC
Sbjct: 303 MPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIEC 362

Query: 367 IIAEQNMVSVALGCATRGRTIAFAGAFAAFFTRAFDQLRMGAISQANINLIGSHCGVSTG 426
            IAEQNMVS+A+GCATR RT+ F   FAAFFTRAFDQ+RM AIS++NINL GSHCGVS G
Sbjct: 363 YIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIG 422

Query: 427 EDGVSQMALEDLAMFRSIPNCTVFYPSDAISTEHAIYLAANTKGMCFIRTSQPETAVIYT 486
           EDG SQMALEDLAMFRS+P  TVFYPSD ++TE A+ LAANTKG+CFIRTS+PE A+IY 
Sbjct: 423 EDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYN 482

Query: 487 PQENFEIGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLSQQGISVRVIDPFTIKPLDA 546
             E+F++GQAKVV    +D+VTVIGAGVTLHEAL AA+ L ++ I++RV+DPFTIKPLD 
Sbjct: 483 NNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDR 542

Query: 547 ATIISSAKATGGRVITVEDHYREGGIGEAVCAAVSREPDILVHQLAVSGVPQRGKTSELL 606
             I+ SA+AT GR++TVEDHY EGGIGEAV +AV  EP I V  LAV+ VP+ GK +ELL
Sbjct: 543 KLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELL 602

Query: 607 DMFGISTRHIIAAV 620
            MFGI    I  AV
Sbjct: 603 KMFGIDRDAIAQAV 616


>gi|225637463 transketolase-like 1 isoform c [Homo sapiens]
          Length = 540

 Score =  837 bits (2161), Expect = 0.0
 Identities = 411/577 (71%), Positives = 476/577 (82%), Gaps = 38/577 (6%)

Query: 49  VSVLFFHTMKYKQTDPEHPDNDRFILSRGHAAPILYAAWVEVGDISESDLLNLRKLHSDL 108
           +SVLFF+ M+YKQ+DPE+PDNDRF+L++                                
Sbjct: 1   MSVLFFYIMRYKQSDPENPDNDRFVLAK-------------------------------- 28

Query: 109 ERHPTPRLPFVDVATGSLGQGLGTACGMAYTGKYLDKASYRVFCLMGDGESSEGSVWEAF 168
                 RL FVDVATG LGQGLG ACGMAYTGKY D+ASYRVFCLM DGESSEGSVWEA 
Sbjct: 29  ------RLSFVDVATGWLGQGLGVACGMAYTGKYFDRASYRVFCLMSDGESSEGSVWEAM 82

Query: 169 AFASHYNLDNLVAVFDVNRLGQSGPAPLEHGADIYQNCCEAFGWNTYLVDGHDVEALCQA 228
           AFAS+Y+LDNLVA+FDVNRLG SG  P EH  +IYQ  CEAFGWNTY+VDG DVEALCQ 
Sbjct: 83  AFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRRCEAFGWNTYVVDGRDVEALCQV 142

Query: 229 FWQASQVKNKPTAIVAKTFKGRGIPNIEDAENWHGKPVPKERADAIVKLIESQIQTNENL 288
           FWQASQVK+KPTA+VAKTFKGRG P+IEDAE+WH KP+P+ERADAI+KLIESQIQT+ NL
Sbjct: 143 FWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNL 202

Query: 289 IPKSPVEDSPQISITDIKMTSPPAYKVGDKIATQKTYGLALAKLGRANERVIVLSGDTMN 348
            P+ P+EDSP+++ITD++MTSPP Y+VGDKIAT+K  GLALAKLG AN RV+VL GDT  
Sbjct: 203 DPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACGLALAKLGYANNRVVVLDGDTRY 262

Query: 349 STFSEIFRKEHPERFIECIIAEQNMVSVALGCATRGRTIAFAGAFAAFFTRAFDQLRMGA 408
           STFSEIF KE+PERFIEC +AEQNMVSVALGCA+RGRTIAFA  FAAF TRAFD +R+G 
Sbjct: 263 STFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHIRIGG 322

Query: 409 ISQANINLIGSHCGVSTGEDGVSQMALEDLAMFRSIPNCTVFYPSDAISTEHAIYLAANT 468
           ++++NIN+IGSHCGVS G+DG SQMALED+AMFR+IP CT+FYP+DA+STEHA+ LAAN 
Sbjct: 323 LAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAANA 382

Query: 469 KGMCFIRTSQPETAVIYTPQENFEIGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLSQ 528
           KGMCFIRT++PET VIYTPQE FEIGQAKV+RH V+DKVTVIGAG+T++EAL AAD LS+
Sbjct: 383 KGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDKVTVIGAGITVYEALAAADELSK 442

Query: 529 QGISVRVIDPFTIKPLDAATIISSAKATGGRVITVEDHYREGGIGEAVCAAVSREPDILV 588
           Q I +RVID FTIKPLD ATI+SSAKAT GR+ITVEDHY +GGIGEAVCAAVS +PDI V
Sbjct: 443 QDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAVSMDPDIQV 502

Query: 589 HQLAVSGVPQRGKTSELLDMFGISTRHIIAAVTLTLM 625
           H LAVSGVPQ GK+ ELLDM+GIS RHII AV   L+
Sbjct: 503 HSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLL 539


>gi|205277465 transketolase isoform 2 [Homo sapiens]
          Length = 540

 Score =  663 bits (1710), Expect = 0.0
 Identities = 331/508 (65%), Positives = 398/508 (78%), Gaps = 12/508 (2%)

Query: 122 ATGSLGQGLGTACGMA---------YTGKYLDKASYRVFCLMGDGESSEGSVWEAFAFAS 172
           AT + G G  T+C  A         +TGKY DKASYRV+CL+GDGE SEGSVWEA AFAS
Sbjct: 29  ATTAAGSGHPTSCCSAAEIMAVLFFHTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFAS 88

Query: 173 HYNLDNLVAVFDVNRLGQSGPAPLEHGADIYQNCCEAFGWNTYLVDGHDVEALCQAFWQA 232
            Y LDNLVA+ D+NRLGQS PAPL+H  DIYQ  CEAFGW+  +VDGH VE LC+AF QA
Sbjct: 89  IYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQA 148

Query: 233 SQVKNKPTAIVAKTFKGRGIPNIEDAENWHGKPVPKERADAIVKLIESQIQTNENLIPKS 292
              K++PTAI+AKTFKGRGI  +ED E+WHGKP+PK  A+ I++ I SQIQ+ + ++   
Sbjct: 149 ---KHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATP 205

Query: 293 PVEDSPQISITDIKMTSPPAYKVGDKIATQKTYGLALAKLGRANERVIVLSGDTMNSTFS 352
           P ED+P + I +I+M S P+YKVGDKIAT+K YG ALAKLG A++R+I L GDT NSTFS
Sbjct: 206 PQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFS 265

Query: 353 EIFRKEHPERFIECIIAEQNMVSVALGCATRGRTIAFAGAFAAFFTRAFDQLRMGAISQA 412
           EIF+KEHP+RFIEC IAEQNMVS+A+GCATR RT+ F   FAAFFTRAFDQ+RM AIS++
Sbjct: 266 EIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISES 325

Query: 413 NINLIGSHCGVSTGEDGVSQMALEDLAMFRSIPNCTVFYPSDAISTEHAIYLAANTKGMC 472
           NINL GSHCGVS GEDG SQMALEDLAMFRS+P  TVFYPSD ++TE A+ LAANTKG+C
Sbjct: 326 NINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGIC 385

Query: 473 FIRTSQPETAVIYTPQENFEIGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLSQQGIS 532
           FIRTS+PE A+IY   E+F++GQAKVV    +D+VTVIGAGVTLHEAL AA+ L ++ I+
Sbjct: 386 FIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKIN 445

Query: 533 VRVIDPFTIKPLDAATIISSAKATGGRVITVEDHYREGGIGEAVCAAVSREPDILVHQLA 592
           +RV+DPFTIKPLD   I+ SA+AT GR++TVEDHY EGGIGEAV +AV  EP I V  LA
Sbjct: 446 IRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLA 505

Query: 593 VSGVPQRGKTSELLDMFGISTRHIIAAV 620
           V+ VP+ GK +ELL MFGI    I  AV
Sbjct: 506 VNRVPRSGKPAELLKMFGIDRDAIAQAV 533



 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 37/53 (69%), Positives = 45/53 (84%)

Query: 7  KPDVKTVQVLRDTANRLRIHSIRATCASGSGQLTSCCSAAEVVSVLFFHTMKY 59
          KPD + +Q L+DTANRLRI SI+AT A+GSG  TSCCSAAE+++VLFFHT KY
Sbjct: 6  KPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTGKY 58


>gi|156564403 pyruvate dehydrogenase (lipoamide) beta [Homo sapiens]
          Length = 359

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 62/247 (25%), Positives = 104/247 (42%), Gaps = 22/247 (8%)

Query: 354 IFRKEHPERFIECIIAEQNMVSVALGCATRGRTIAFAGAFAAFFTRAFDQL--------- 404
           +++K   +R I+  I+E     +A+G A  G           F  +A DQ+         
Sbjct: 73  LWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYY 132

Query: 405 RMGAISQANINLIGSHCGVSTGEDGVSQMALEDLAMFRSIPNCTVFYPSDAISTEHAIYL 464
             G +    I   G + G S G    +Q +    A +   P   V  P ++   +  I  
Sbjct: 133 MSGGLQPVPIVFRGPN-GASAGV--AAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKS 189

Query: 465 AANTKGMCFIRTSQPETAVIYT-PQEN------FEIGQAKVVRHGVNDKVTVIGAGVTLH 517
           A        +  ++    V +  P E         IG+AK+ R G +  +TV+     + 
Sbjct: 190 AIRDNNPVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTH--ITVVSHSRPVG 247

Query: 518 EALEAADHLSQQGISVRVIDPFTIKPLDAATIISSAKATGGRVITVEDHYREGGIGEAVC 577
             LEAA  LS++G+   VI+  TI+P+D  TI +S   T   ++TVE  + + G+G  +C
Sbjct: 248 HCLEAAAVLSKEGVECEVINMRTIRPMDMETIEASVMKT-NHLVTVEGGWPQFGVGAEIC 306

Query: 578 AAVSREP 584
           A +   P
Sbjct: 307 ARIMEGP 313


>gi|4557353 branched chain keto acid dehydrogenase E1 beta precursor
           [Homo sapiens]
          Length = 392

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 67/272 (24%), Positives = 101/272 (37%), Gaps = 32/272 (11%)

Query: 335 ANERVIVLSGDTMNSTFSEIFR-------KEHPERFIECIIAEQNMVSVALGCATRGRTI 387
           A +   V+ G+ +   F  +FR       K   +R     + EQ +V   +G A  G T 
Sbjct: 86  AKDPTAVIFGEDV--AFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATA 143

Query: 388 AFAGAFAAFFTRAFDQLRMGAISQANINLIGSHCGVSTGED-------GVSQMALEDLAM 440
                FA +   AFDQ+   A      +    +CG  T          G    +    A 
Sbjct: 144 IAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAF 203

Query: 441 FRSIPNCTVFYPSDAISTEHAIYLAANTKGMCFIRTSQPETAVIY------TPQE--NFE 492
           F   P   V  P      +  +      K  C       E  ++Y       P E  N  
Sbjct: 204 FAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFF----EPKILYRAAAEEVPIEPYNIP 259

Query: 493 IGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLSQQ-GISVRVIDPFTIKPLDAATIIS 551
           + QA+V++ G +  VT++  G  +H   E A    ++ G+S  VID  TI P D  TI  
Sbjct: 260 LSQAEVIQEGSD--VTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICK 317

Query: 552 SAKATGGRVITVEDHYREGGIGEAVCAAVSRE 583
           S   T GR++   +    GG    + + V  E
Sbjct: 318 SVIKT-GRLLISHEAPLTGGFASEISSTVQEE 348


>gi|34101272 branched chain keto acid dehydrogenase E1 beta
           precursor [Homo sapiens]
          Length = 392

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 67/272 (24%), Positives = 101/272 (37%), Gaps = 32/272 (11%)

Query: 335 ANERVIVLSGDTMNSTFSEIFR-------KEHPERFIECIIAEQNMVSVALGCATRGRTI 387
           A +   V+ G+ +   F  +FR       K   +R     + EQ +V   +G A  G T 
Sbjct: 86  AKDPTAVIFGEDV--AFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATA 143

Query: 388 AFAGAFAAFFTRAFDQLRMGAISQANINLIGSHCGVSTGED-------GVSQMALEDLAM 440
                FA +   AFDQ+   A      +    +CG  T          G    +    A 
Sbjct: 144 IAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAF 203

Query: 441 FRSIPNCTVFYPSDAISTEHAIYLAANTKGMCFIRTSQPETAVIY------TPQE--NFE 492
           F   P   V  P      +  +      K  C       E  ++Y       P E  N  
Sbjct: 204 FAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFF----EPKILYRAAAEEVPIEPYNIP 259

Query: 493 IGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLSQQ-GISVRVIDPFTIKPLDAATIIS 551
           + QA+V++ G +  VT++  G  +H   E A    ++ G+S  VID  TI P D  TI  
Sbjct: 260 LSQAEVIQEGSD--VTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICK 317

Query: 552 SAKATGGRVITVEDHYREGGIGEAVCAAVSRE 583
           S   T GR++   +    GG    + + V  E
Sbjct: 318 SVIKT-GRLLISHEAPLTGGFASEISSTVQEE 348


>gi|11386135 branched chain keto acid dehydrogenase E1, alpha
           polypeptide [Homo sapiens]
          Length = 445

 Score = 38.5 bits (88), Expect = 0.019
 Identities = 40/143 (27%), Positives = 63/143 (44%), Gaps = 12/143 (8%)

Query: 109 ERHPTPRLPFVDVATGSLGQGLGTACGMAYTGKYLDKASYRVFCLMGDGESSEGSVWEAF 168
           ERH      FV +++  L   +  A G AY  K  + A+  V C  G+G +SEG     F
Sbjct: 199 ERH------FVTISS-PLATQIPQAVGAAYAAKRAN-ANRVVICYFGEGAASEGDAHAGF 250

Query: 169 AFASHYNLDNLVAVFDVNRLGQSGPAPLEHGADIYQNCCEAFGWNTYLVDGHDVEALCQA 228
            FA+      ++     N    S P   ++  D        +G  +  VDG+DV A+  A
Sbjct: 251 NFAATLECP-IIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNA 309

Query: 229 FWQASQ---VKNKPTAIVAKTFK 248
             +A +    +N+P  I A T++
Sbjct: 310 TKEARRRAVAENQPFLIEAMTYR 332


>gi|52317186 olfactory receptor, family 13, subfamily D, member 1
           [Homo sapiens]
          Length = 346

 Score = 30.8 bits (68), Expect = 3.9
 Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 4/60 (6%)

Query: 28  IRATCASGSGQLTSCCSAAEVVSVLFFHTMKYKQTDPEHPD---NDRFI-LSRGHAAPIL 83
           +R  CA G  +  S CSA  +V +LF+ +  +    P+  +   +D  I LS G  +P+L
Sbjct: 258 LRINCAEGRKKAFSTCSAHSIVVILFYGSALFMYMKPKSKNTNTSDEIIGLSYGVVSPML 317


>gi|41054864 regulating synaptic membrane exocytosis 1 [Homo
           sapiens]
          Length = 1692

 Score = 30.4 bits (67), Expect = 5.1
 Identities = 17/69 (24%), Positives = 32/69 (46%), Gaps = 5/69 (7%)

Query: 256 EDAENWHGKPVPKERADAIVKLI-ESQIQTNENLIPKSPVEDSPQISITDIKMTSPPAYK 314
           ++   W+GKP+P    + +  +I ES+ +    +I   P+ D P+I     + + PP   
Sbjct: 654 DEVLEWNGKPLPGATNEEVYNIILESKSEPQVEIIVSRPIGDIPRIP----ESSHPPLES 709

Query: 315 VGDKIATQK 323
                 +QK
Sbjct: 710 SSSSFESQK 718


>gi|4505685 pyruvate dehydrogenase E1 alpha 1 precursor [Homo
           sapiens]
          Length = 390

 Score = 30.0 bits (66), Expect = 6.7
 Identities = 20/64 (31%), Positives = 35/64 (54%), Gaps = 8/64 (12%)

Query: 126 LGQGLGTACGMAYTGKYLDKASYRVFCLMGDGESSEGSVWEAFAFASHYNLDNLVAVFDV 185
           LG G+  AC   Y GK  D+    ++   GDG +++G ++EA+  A+ + L   + + + 
Sbjct: 173 LGAGIALAC--KYNGK--DEVCLTLY---GDGAANQGQIFEAYNMAALWKLP-CIFICEN 224

Query: 186 NRLG 189
           NR G
Sbjct: 225 NRYG 228


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,503,399
Number of Sequences: 37866
Number of extensions: 977180
Number of successful extensions: 2059
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2042
Number of HSP's gapped (non-prelim): 18
length of query: 626
length of database: 18,247,518
effective HSP length: 108
effective length of query: 518
effective length of database: 14,157,990
effective search space: 7333838820
effective search space used: 7333838820
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.