Guide to the Human Genome
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Search of human proteins with 13376852

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13376852 CD276 antigen isoform b [Homo sapiens]
         (316 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13376852 CD276 antigen isoform b [Homo sapiens]                    639   0.0  
gi|67188443 CD276 antigen isoform a [Homo sapiens]                    578   e-165
gi|7661534 CD274 molecule [Homo sapiens]                              119   4e-27
gi|27477039 inducible T-cell co-stimulator ligand [Homo sapiens]      104   1e-22
gi|34932496 butyrophilin, subfamily 3, member A2 precursor [Homo...    99   5e-21
gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]       97   1e-20
gi|5901908 butyrophilin, subfamily 3, member A3 isoform a [Homo ...    96   3e-20
gi|99028881 V-set domain containing T cell activation inhibitor ...    92   5e-19
gi|37221189 butyrophilin, subfamily 3, member A1 isoform b [Homo...    89   4e-18
gi|222418660 butyrophilin, subfamily 3, member A1 isoform d [Hom...    89   4e-18
gi|37595558 butyrophilin, subfamily 3, member A1 isoform a [Homo...    89   4e-18
gi|229577039 butyrophilin-like 8 isoform 4 precursor [Homo sapiens]    86   3e-17
gi|94957742 butyrophilin-like 8 isoform 2 precursor [Homo sapiens]     86   3e-17
gi|13376271 butyrophilin-like 8 isoform 1 precursor [Homo sapiens]     86   3e-17
gi|37574628 butyrophilin, subfamily 3, member A3 isoform b [Homo...    86   3e-17
gi|60460897 butyrophilin-like 9 [Homo sapiens]                         84   2e-16
gi|9624969 butyrophilin-like 2 [Homo sapiens]                          82   8e-16
gi|5921461 butyrophilin, subfamily 2, member A1 isoform 1 precur...    81   1e-15
gi|17975772 butyrophilin, subfamily 2, member A1 isoform 2 precu...    81   1e-15
gi|5901964 HERV-H LTR-associating 2 [Homo sapiens]                     71   1e-12
gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo ...    71   1e-12
gi|190014605 programmed cell death 1 ligand 2 [Homo sapiens]           70   3e-12
gi|56788393 myelin oligodendrocyte glycoprotein isoform beta5 pr...    69   5e-12
gi|56788391 myelin oligodendrocyte glycoprotein isoform beta2 pr...    69   5e-12
gi|56788389 myelin oligodendrocyte glycoprotein isoform alpha3 p...    69   5e-12
gi|56788387 myelin oligodendrocyte glycoprotein isoform beta3 pr...    69   5e-12
gi|56788385 myelin oligodendrocyte glycoprotein isoform beta1 pr...    69   5e-12
gi|56788383 myelin oligodendrocyte glycoprotein isoform alpha2 p...    69   5e-12
gi|56788381 myelin oligodendrocyte glycoprotein isoform alpha1 p...    69   5e-12
gi|56788397 myelin oligodendrocyte glycoprotein isoform beta4 pr...    68   1e-11

>gi|13376852 CD276 antigen isoform b [Homo sapiens]
          Length = 316

 Score =  639 bits (1648), Expect = 0.0
 Identities = 316/316 (100%), Positives = 316/316 (100%)

Query: 1   MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSL 60
           MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSL
Sbjct: 1   MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSL 60

Query: 61  AQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSF 120
           AQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSF
Sbjct: 61  AQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSF 120

Query: 121 TCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQD 180
           TCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQD
Sbjct: 121 TCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQD 180

Query: 181 GQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQ 240
           GQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQ
Sbjct: 181 GQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQ 240

Query: 241 PMTFPPEALWVTVGLSVCLIALLVALAFVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQ 300
           PMTFPPEALWVTVGLSVCLIALLVALAFVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQ
Sbjct: 241 PMTFPPEALWVTVGLSVCLIALLVALAFVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQ 300

Query: 301 PLKHSDSKEDDGQEIA 316
           PLKHSDSKEDDGQEIA
Sbjct: 301 PLKHSDSKEDDGQEIA 316


>gi|67188443 CD276 antigen isoform a [Homo sapiens]
          Length = 534

 Score =  578 bits (1489), Expect = e-165
 Identities = 287/291 (98%), Positives = 289/291 (99%)

Query: 26  TGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQ 85
           TGA+EVQVPEDPVVALVGTDATL CSFSPEPGFSLAQLNLIWQLTDTKQLVHSF EG+DQ
Sbjct: 244 TGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQ 303

Query: 86  GSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKP 145
           GSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKP
Sbjct: 304 GSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKP 363

Query: 146 SMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVH 205
           SMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVH
Sbjct: 364 SMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVH 423

Query: 206 SVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIALLVA 265
           SVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIALLVA
Sbjct: 424 SVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIALLVA 483

Query: 266 LAFVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPLKHSDSKEDDGQEIA 316
           LAFVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPLKHSDSKEDDGQEIA
Sbjct: 484 LAFVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPLKHSDSKEDDGQEIA 534



 Score =  478 bits (1230), Expect = e-135
 Identities = 240/253 (94%), Positives = 243/253 (96%), Gaps = 2/253 (0%)

Query: 1   MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSL 60
           MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSL
Sbjct: 1   MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSL 60

Query: 61  AQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSF 120
           AQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSF
Sbjct: 61  AQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSF 120

Query: 121 TCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQD 180
           TCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSY+GYPEAEVFWQD
Sbjct: 121 TCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYQGYPEAEVFWQD 180

Query: 181 GQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQ 240
           GQGVPLTGNVTTSQMANEQGLFDVHS+LRVVLGANGTYSCLVRNPVLQQDAH SVTIT  
Sbjct: 181 GQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVTIT-- 238

Query: 241 PMTFPPEALWVTV 253
           P   P  A+ V V
Sbjct: 239 PQRSPTGAVEVQV 251


>gi|7661534 CD274 molecule [Homo sapiens]
          Length = 290

 Score =  119 bits (298), Expect = 4e-27
 Identities = 82/273 (30%), Positives = 130/273 (47%), Gaps = 13/273 (4%)

Query: 25  LTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTK--QLVHSFAEG 82
           L  A  V VP+D  V   G++ T+ C F  E    LA L + W++ D    Q VH   + 
Sbjct: 15  LLNAFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDL 74

Query: 83  QDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPY 142
           + Q S+Y  R  L  D L+ GNA+L++  V++ D G + C +S        ++++V APY
Sbjct: 75  KVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPY 134

Query: 143 SKPSMTLEPNKDLRPGDTVT----ITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANE 198
           +K       N+ +   D VT    +TC +  GYP+AEV W       L+G  TT+    E
Sbjct: 135 NKI------NQRILVVDPVTSEHELTCQA-EGYPKAEVIWTSSDHQVLSGKTTTTNSKRE 187

Query: 199 QGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVC 258
           + LF+V S LR+    N  + C  R    +++    + I   P+  PP      V L   
Sbjct: 188 EKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERTHLVILGAI 247

Query: 259 LIALLVALAFVCWRKIKQSCEEENAGAEDQDGE 291
           L+ L VAL F+   +  +  + +  G +D + +
Sbjct: 248 LLCLGVALTFIFRLRKGRMMDVKKCGIQDTNSK 280


>gi|27477039 inducible T-cell co-stimulator ligand [Homo sapiens]
          Length = 302

 Score =  104 bits (259), Expect = 1e-22
 Identities = 89/292 (30%), Positives = 131/292 (44%), Gaps = 41/292 (14%)

Query: 4   RRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQL 63
           R GSPG           L F L  +L     E  V A+VG+D  L C+      F L  +
Sbjct: 2   RLGSPG-----------LLFLLFSSLRADTQEKEVRAMVGSDVELSCACPEGSRFDLNDV 50

Query: 64  NLIWQLTDTKQLV------HSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADE 117
            + WQ +++K +V      +S  E  D  S Y NR  + P  + +G+ SLRL  V   DE
Sbjct: 51  YVYWQTSESKTVVTYHIPQNSSLENVD--SRYRNRALMSPAGMLRGDFSLRLFNVTPQDE 108

Query: 118 GSFTCFVSIRDFG-----SAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYP 172
             F C V  +  G     S  V+L VAA +S P ++   +      D +T TC+S  GYP
Sbjct: 109 QKFHCLVLSQSLGFQEVLSVEVTLHVAANFSVPVVSAPHSPS---QDELTFTCTSINGYP 165

Query: 173 EAEVFWQDGQGVPLTGNVTTSQ--MANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQD 230
              V+W +     L      +     N +GL+DV SVLR+    +    C + N +LQQ+
Sbjct: 166 RPNVYWINKTDNSLLDQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQN 225

Query: 231 -AHGSVT---------ITGQPMTFPPE--ALWVTVGLSVCLIALLVALAFVC 270
              GS T         IT  P++   +  A W  + +   L+ + VA+ +VC
Sbjct: 226 LTVGSQTGNDIGERDKITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWVC 277


>gi|34932496 butyrophilin, subfamily 3, member A2 precursor [Homo
           sapiens]
          Length = 334

 Score = 99.0 bits (245), Expect = 5e-21
 Identities = 71/272 (26%), Positives = 127/272 (46%), Gaps = 12/272 (4%)

Query: 10  MGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQL 69
           +  HV   L  L    +    V  P  P++A+VG DA L C   P    S   + L W  
Sbjct: 12  LNFHVSLLLVQLLTPCSAQFSVLGPSGPILAMVGEDADLPCHLFPT--MSAETMELKWVS 69

Query: 70  TDTKQLVHSFAEGQD----QGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVS 125
           +  +Q+V+ +A+G++    Q + Y  RT++  D +  G A+LR+  V  +D G + C+  
Sbjct: 70  SSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQ 129

Query: 126 IRDF-GSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGV 184
             DF   A V L+VAA  S   + ++  +D      + + C S   YP+ ++ W + +G 
Sbjct: 130 DGDFYEKALVELKVAALGSNLHVEVKGYED----GGIHLECRSTGWYPQPQIQWSNAKGE 185

Query: 185 PLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTF 244
            +   V    +A+  GL++V + + +  G+    SC++RN +L  +   S++I       
Sbjct: 186 NIPA-VEAPVVADGVGLYEVAASVIMRGGSGEGVSCIIRNSLLGLEKTASISIADPFFRS 244

Query: 245 PPEALWVTVGLSVCLIALLVALAFVCWRKIKQ 276
               +    G    L+ LL   ++  WR+ K+
Sbjct: 245 AQPWIAALAGTLPILLLLLAGASYFLWRQQKE 276


>gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]
          Length = 526

 Score = 97.4 bits (241), Expect = 1e-20
 Identities = 73/247 (29%), Positives = 123/247 (49%), Gaps = 18/247 (7%)

Query: 34  PEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQD--QGSAYAN 91
           P +P++A+VG DA L C  SP       +L    +      LVH     Q+  Q   Y  
Sbjct: 34  PPEPILAVVGEDAELPCRLSPNASAEHLELRWFRKKVSPAVLVHRDGREQEAEQMPEYRG 93

Query: 92  RTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGS---AAVSLQVAAPYSKPSMT 148
           R  L  D +A+G  +LR++ VRV+D+G +TCF   R+ GS   A V L+VAA  S P ++
Sbjct: 94  RATLVQDGIAKGRVALRIRGVRVSDDGEYTCF--FREDGSYEEALVHLKVAALGSDPHIS 151

Query: 149 LEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVL 208
           ++    ++    + + C+S   YPE +V W+  +G     + + S+  +E+GLF V + +
Sbjct: 152 MQ----VQENGEICLECTSVGWYPEPQVQWRTSKGEKFP-STSESRNPDEEGLFTVAASV 206

Query: 209 RVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIA---LLVA 265
            +   +    SC ++N +L Q+    ++I     + P    W+ V ++V L+    L + 
Sbjct: 207 IIRDTSAKNVSCYIQNLLLGQEKKVEISIPAS--SLPRLTPWI-VAVAVILMVLGLLTIG 263

Query: 266 LAFVCWR 272
             F  WR
Sbjct: 264 SIFFTWR 270


>gi|5901908 butyrophilin, subfamily 3, member A3 isoform a [Homo
           sapiens]
          Length = 584

 Score = 96.3 bits (238), Expect = 3e-20
 Identities = 72/274 (26%), Positives = 126/274 (45%), Gaps = 16/274 (5%)

Query: 10  MGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQL 69
           +  HV   L  L    +    V  P  P++A+VG DA L C   P    S   + L W  
Sbjct: 12  LNFHVSLFLVQLLTPCSAQFSVLGPSGPILAMVGEDADLPCHLFPT--MSAETMELRWVS 69

Query: 70  TDTKQLVHSFAEGQD----QGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVS 125
           +  +Q+V+ +A+G++    Q + Y  RT++  D +  G A+LR+  V  +D G + C+  
Sbjct: 70  SSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQ 129

Query: 126 IRDF-GSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQD--GQ 182
             DF   A V L+VAA  S   + ++  +D      + + C S   YP+ ++ W D  G+
Sbjct: 130 DGDFYEKALVELKVAALGSDLHIEVKGYED----GGIHLECRSTGWYPQPQIKWSDTKGE 185

Query: 183 GVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPM 242
            +P    V    +A+  GL+ V + + +   + G  SC++RN +L  +   S++I     
Sbjct: 186 NIPA---VEAPVVADGVGLYAVAASVIMRGSSGGGVSCIIRNSLLGLEKTASISIADPFF 242

Query: 243 TFPPEALWVTVGLSVCLIALLVALAFVCWRKIKQ 276
                 +    G     + LL   ++  WR+ K+
Sbjct: 243 RSAQPWIAALAGTLPISLLLLAGASYFLWRQQKE 276


>gi|99028881 V-set domain containing T cell activation inhibitor 1
           [Homo sapiens]
          Length = 282

 Score = 92.4 bits (228), Expect = 5e-19
 Identities = 70/232 (30%), Positives = 114/232 (49%), Gaps = 19/232 (8%)

Query: 15  GAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQ 74
           GA    + F ++G   + V        +G D  L C+F  EP   L+ + + W       
Sbjct: 21  GAIALIIGFGISGRHSITVTTVASAGNIGEDGILSCTF--EPDIKLSDIVIQWLKEGVLG 78

Query: 75  LVHSFAEGQD----QGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCF-VSIRDF 129
           LVH F EG+D    Q   +  RTA+F D +  GNASLRL+ V++ D G++ C+ ++ +  
Sbjct: 79  LVHEFKEGKDELSEQDEMFRGRTAVFADQVIVGNASLRLKNVQLTDAGTYKCYIITSKGK 138

Query: 130 GSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFW--QDGQGVPLT 187
           G+A +  +  A +S P + ++ N       + T+ C + R +P+  V W  Q  QG   +
Sbjct: 139 GNANLEYKTGA-FSMPEVNVDYN-----ASSETLRCEAPRWFPQPTVVWASQVDQGANFS 192

Query: 188 GNVTTS-QMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTIT 238
               TS ++ +E     V SVL  V   N TYSC++ N + +  A G + +T
Sbjct: 193 EVSNTSFELNSENVTMKVVSVLYNVT-INNTYSCMIENDIAK--ATGDIKVT 241


>gi|37221189 butyrophilin, subfamily 3, member A1 isoform b [Homo
           sapiens]
          Length = 352

 Score = 89.4 bits (220), Expect = 4e-18
 Identities = 73/280 (26%), Positives = 128/280 (45%), Gaps = 18/280 (6%)

Query: 34  PEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQD----QGSAY 89
           P  P++A+VG DA L C   P    S   + L W  +  +Q+V+ +A+G++    Q + Y
Sbjct: 36  PSGPILAMVGEDADLPCHLFPT--MSAETMELKWVSSSLRQVVNVYADGKEVEDRQSAPY 93

Query: 90  ANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAPYSKPSMT 148
             RT++  D +  G A+LR+  V  +D G + C+    DF   A V L+VAA  S   + 
Sbjct: 94  RGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHVD 153

Query: 149 LEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVL 208
           ++  KD      + + C S   YP+ ++ W + +G  +   V    +A+  GL+ V + +
Sbjct: 154 VKGYKD----GGIHLECRSTGWYPQPQIQWSNNKGENIP-TVEAPVVADGVGLYAVAASV 208

Query: 209 RVVLGANGT-YSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIALLVALA 267
            ++ G++G   SC +R+ +L  +   S++I           +    G    L+ LL    
Sbjct: 209 -IMRGSSGEGVSCTIRSSLLGLEKTASISIADPFFRSAQRWIAALAGTLPVLLLLLGGAG 267

Query: 268 FVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPLKHSDS 307
           +  W    Q  EE+      +  E E  + A   +K   S
Sbjct: 268 YFLW----QQQEEKKTQFRKKKREQELREMAWSTMKQEQS 303


>gi|222418660 butyrophilin, subfamily 3, member A1 isoform d [Homo
           sapiens]
          Length = 378

 Score = 89.4 bits (220), Expect = 4e-18
 Identities = 73/280 (26%), Positives = 128/280 (45%), Gaps = 18/280 (6%)

Query: 34  PEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQD----QGSAY 89
           P  P++A+VG DA L C   P    S   + L W  +  +Q+V+ +A+G++    Q + Y
Sbjct: 36  PSGPILAMVGEDADLPCHLFPT--MSAETMELKWVSSSLRQVVNVYADGKEVEDRQSAPY 93

Query: 90  ANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAPYSKPSMT 148
             RT++  D +  G A+LR+  V  +D G + C+    DF   A V L+VAA  S   + 
Sbjct: 94  RGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHVD 153

Query: 149 LEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVL 208
           ++  KD      + + C S   YP+ ++ W + +G  +   V    +A+  GL+ V + +
Sbjct: 154 VKGYKD----GGIHLECRSTGWYPQPQIQWSNNKGENIP-TVEAPVVADGVGLYAVAASV 208

Query: 209 RVVLGANGT-YSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIALLVALA 267
            ++ G++G   SC +R+ +L  +   S++I           +    G    L+ LL    
Sbjct: 209 -IMRGSSGEGVSCTIRSSLLGLEKTASISIADPFFRSAQRWIAALAGTLPVLLLLLGGAG 267

Query: 268 FVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPLKHSDS 307
           +  W    Q  EE+      +  E E  + A   +K   S
Sbjct: 268 YFLW----QQQEEKKTQFRKKKREQELREMAWSTMKQEQS 303


>gi|37595558 butyrophilin, subfamily 3, member A1 isoform a [Homo
           sapiens]
          Length = 513

 Score = 89.4 bits (220), Expect = 4e-18
 Identities = 73/280 (26%), Positives = 128/280 (45%), Gaps = 18/280 (6%)

Query: 34  PEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQD----QGSAY 89
           P  P++A+VG DA L C   P    S   + L W  +  +Q+V+ +A+G++    Q + Y
Sbjct: 36  PSGPILAMVGEDADLPCHLFPT--MSAETMELKWVSSSLRQVVNVYADGKEVEDRQSAPY 93

Query: 90  ANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAPYSKPSMT 148
             RT++  D +  G A+LR+  V  +D G + C+    DF   A V L+VAA  S   + 
Sbjct: 94  RGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHVD 153

Query: 149 LEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVL 208
           ++  KD      + + C S   YP+ ++ W + +G  +   V    +A+  GL+ V + +
Sbjct: 154 VKGYKD----GGIHLECRSTGWYPQPQIQWSNNKGENIP-TVEAPVVADGVGLYAVAASV 208

Query: 209 RVVLGANGT-YSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIALLVALA 267
            ++ G++G   SC +R+ +L  +   S++I           +    G    L+ LL    
Sbjct: 209 -IMRGSSGEGVSCTIRSSLLGLEKTASISIADPFFRSAQRWIAALAGTLPVLLLLLGGAG 267

Query: 268 FVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPLKHSDS 307
           +  W    Q  EE+      +  E E  + A   +K   S
Sbjct: 268 YFLW----QQQEEKKTQFRKKKREQELREMAWSTMKQEQS 303


>gi|229577039 butyrophilin-like 8 isoform 4 precursor [Homo sapiens]
          Length = 340

 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 66/217 (30%), Positives = 103/217 (47%), Gaps = 14/217 (6%)

Query: 26  TGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQ 85
           +G  +V  P+ PV ALVG DA   C  SP+      ++           +VH + +G+DQ
Sbjct: 16  SGQWQVFGPDKPVQALVGEDAAFSCFLSPKTNAEAMEVRFF--RGQFSSVVHLYRDGKDQ 73

Query: 86  G----SAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAV-SLQVAA 140
                  Y  RT L  D +A+G  SLRL+ + V D G + C +S + +   A+  LQV+A
Sbjct: 74  PFMQMPQYQGRTKLVKDSIAEGRISLRLENITVLDAGLYGCRISSQSYYQKAIWELQVSA 133

Query: 141 PYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQG 200
             S P +++    D      + + C S   +P     W+  QG  L+ +  T++  +  G
Sbjct: 134 LGSVPLISITGYVD----RDIQLLCQSSGWFPRPTAKWKGPQGQDLSTDSRTNR--DMHG 187

Query: 201 LFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTI 237
           LFDV   L V   A G+ SC +R+  L ++    V I
Sbjct: 188 LFDVEISLTVQENA-GSISCSMRHAHLSREVESRVQI 223


>gi|94957742 butyrophilin-like 8 isoform 2 precursor [Homo sapiens]
          Length = 500

 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 66/217 (30%), Positives = 103/217 (47%), Gaps = 14/217 (6%)

Query: 26  TGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQ 85
           +G  +V  P+ PV ALVG DA   C  SP+      ++           +VH + +G+DQ
Sbjct: 16  SGQWQVFGPDKPVQALVGEDAAFSCFLSPKTNAEAMEVRFF--RGQFSSVVHLYRDGKDQ 73

Query: 86  G----SAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAV-SLQVAA 140
                  Y  RT L  D +A+G  SLRL+ + V D G + C +S + +   A+  LQV+A
Sbjct: 74  PFMQMPQYQGRTKLVKDSIAEGRISLRLENITVLDAGLYGCRISSQSYYQKAIWELQVSA 133

Query: 141 PYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQG 200
             S P +++    D      + + C S   +P     W+  QG  L+ +  T++  +  G
Sbjct: 134 LGSVPLISITGYVD----RDIQLLCQSSGWFPRPTAKWKGPQGQDLSTDSRTNR--DMHG 187

Query: 201 LFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTI 237
           LFDV   L V   A G+ SC +R+  L ++    V I
Sbjct: 188 LFDVEISLTVQENA-GSISCSMRHAHLSREVESRVQI 223


>gi|13376271 butyrophilin-like 8 isoform 1 precursor [Homo sapiens]
          Length = 347

 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 66/217 (30%), Positives = 103/217 (47%), Gaps = 14/217 (6%)

Query: 26  TGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQ 85
           +G  +V  P+ PV ALVG DA   C  SP+      ++           +VH + +G+DQ
Sbjct: 16  SGQWQVFGPDKPVQALVGEDAAFSCFLSPKTNAEAMEVRFF--RGQFSSVVHLYRDGKDQ 73

Query: 86  G----SAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAV-SLQVAA 140
                  Y  RT L  D +A+G  SLRL+ + V D G + C +S + +   A+  LQV+A
Sbjct: 74  PFMQMPQYQGRTKLVKDSIAEGRISLRLENITVLDAGLYGCRISSQSYYQKAIWELQVSA 133

Query: 141 PYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQG 200
             S P +++    D      + + C S   +P     W+  QG  L+ +  T++  +  G
Sbjct: 134 LGSVPLISITGYVD----RDIQLLCQSSGWFPRPTAKWKGPQGQDLSTDSRTNR--DMHG 187

Query: 201 LFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTI 237
           LFDV   L V   A G+ SC +R+  L ++    V I
Sbjct: 188 LFDVEISLTVQENA-GSISCSMRHAHLSREVESRVQI 223


>gi|37574628 butyrophilin, subfamily 3, member A3 isoform b [Homo
           sapiens]
          Length = 542

 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 64/243 (26%), Positives = 114/243 (46%), Gaps = 16/243 (6%)

Query: 41  LVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQD----QGSAYANRTALF 96
           +VG DA L C   P    S   + L W  +  +Q+V+ +A+G++    Q + Y  RT++ 
Sbjct: 1   MVGEDADLPCHLFPT--MSAETMELRWVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSIL 58

Query: 97  PDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAPYSKPSMTLEPNKDL 155
            D +  G A+LR+  V  +D G + C+    DF   A V L+VAA  S   + ++  +D 
Sbjct: 59  RDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHIEVKGYED- 117

Query: 156 RPGDTVTITCSSYRGYPEAEVFWQD--GQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLG 213
                + + C S   YP+ ++ W D  G+ +P    V    +A+  GL+ V + + +   
Sbjct: 118 ---GGIHLECRSTGWYPQPQIKWSDTKGENIPA---VEAPVVADGVGLYAVAASVIMRGS 171

Query: 214 ANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIALLVALAFVCWRK 273
           + G  SC++RN +L  +   S++I           +    G     + LL   ++  WR+
Sbjct: 172 SGGGVSCIIRNSLLGLEKTASISIADPFFRSAQPWIAALAGTLPISLLLLAGASYFLWRQ 231

Query: 274 IKQ 276
            K+
Sbjct: 232 QKE 234


>gi|60460897 butyrophilin-like 9 [Homo sapiens]
          Length = 535

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 79/265 (29%), Positives = 127/265 (47%), Gaps = 17/265 (6%)

Query: 30  EVQV--PEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQD--- 84
           EV+V  PE P++ALVG +    C   P+      Q+ + W  + T  +VH + E Q+   
Sbjct: 37  EVKVLGPEYPILALVGEEVEFPCHLWPQ--LDAQQMEIRWFRSQTFNVVHLYQEQQELPG 94

Query: 85  -QGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTC-FVSIRDFGSAAVSLQVAAPY 142
            Q  A+ NRT L  D +A G+  L+L  +  +D+G++ C F S    G A   L+VA   
Sbjct: 95  RQMPAFRNRTKLVKDDIAYGSVVLQLHSIIPSDKGTYGCRFHSDNFSGEALWELEVAGLG 154

Query: 143 SKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLF 202
           S P ++LE  K+      + +   S   YP+ +V W+D QG  L      + + + Q LF
Sbjct: 155 SDPHLSLEGFKE----GGIQLRLRSSGWYPKPKVQWRDHQGQCLPPEF-EAIVWDAQDLF 209

Query: 203 DVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVC-LIA 261
            + + + V  GA    S  ++N +L Q     V I    +  P  + W +  ++   L+ 
Sbjct: 210 SLETSVVVRAGALSNVSVSIQNLLLSQKKELVVQIA--DVFVPGASAWKSAFVATLPLLL 267

Query: 262 LLVALAFVCWRKIKQSCEEENAGAE 286
           +L ALA    RK ++S E+    AE
Sbjct: 268 VLAALALGVLRKQRRSREKLRKQAE 292


>gi|9624969 butyrophilin-like 2 [Homo sapiens]
          Length = 455

 Score = 81.6 bits (200), Expect = 8e-16
 Identities = 57/219 (26%), Positives = 104/219 (47%), Gaps = 16/219 (7%)

Query: 28  ALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQ---- 83
           +L+V  P  P++  VG D  L C  SP+   +   + + W  +     VH + +G     
Sbjct: 245 SLKVNGPSQPILVRVGEDIQLTCYLSPKA--NAQSMEVRWDRSHRYPAVHVYMDGDHVAG 302

Query: 84  DQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRD-FGSAAVSLQVAAPY 142
           +Q + Y  RT L  D + +G  +L++   R +D+G + C     D +  A++ L+V +  
Sbjct: 303 EQMAEYRGRTVLVSDAIDEGRLTLQILSARPSDDGQYRCLFEKDDVYQEASLDLKVVSLG 362

Query: 143 SKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQD--GQGVPLTGNVTTSQMANEQG 200
           S P +T+E  +D      +   CSS   +P+  V W+D  G+ +P +    T       G
Sbjct: 363 SSPLITVEGQED----GEMQPMCSSDGWFPQPHVPWRDMEGKTIPSSSQALTQ---GSHG 415

Query: 201 LFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITG 239
           LF V ++LRV   +    +C +  P L ++   + +++G
Sbjct: 416 LFHVQTLLRVTNISAVDVTCSISIPFLGEEKIATFSLSG 454



 Score = 79.0 bits (193), Expect = 5e-15
 Identities = 62/244 (25%), Positives = 116/244 (47%), Gaps = 22/244 (9%)

Query: 34  PEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQD----QGSAY 89
           P  P++A VG DA L C   P+   +   + + W  ++    V    +G +    Q   Y
Sbjct: 34  PAHPILAGVGEDALLTCQLLPKR--TTMHVEVRWYRSEPSTPVFVHRDGVEVTEMQMEEY 91

Query: 90  ANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAPYSKPSMT 148
                   + +A+GN +L++  ++ +D G + C     ++ G  ++ L+VA   S PS+ 
Sbjct: 92  RGWVEWIENGIAKGNVALKIHNIQPSDNGQYWCHFQDGNYCGETSLLLKVAGLGSAPSIH 151

Query: 149 LEPNKDLRPGDT-VTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSV 207
           +E      PG++ V + C++   +PE +V+W+D +G  L   V+  ++ ++ GLF   + 
Sbjct: 152 MEG-----PGESGVQLVCTARGWFPEPQVYWEDIRGEKLLA-VSEHRIQDKDGLFYAEAT 205

Query: 208 LRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMT--------FPPEALWVTVGLSVCL 259
           L V   +  + SCLV NPVL ++    +++  +  T         P + + V VG  + L
Sbjct: 206 LVVRNASAESVSCLVHNPVLTEEKGSVISLPEKLQTELASLKVNGPSQPILVRVGEDIQL 265

Query: 260 IALL 263
              L
Sbjct: 266 TCYL 269


>gi|5921461 butyrophilin, subfamily 2, member A1 isoform 1 precursor
           [Homo sapiens]
          Length = 527

 Score = 80.9 bits (198), Expect = 1e-15
 Identities = 73/288 (25%), Positives = 131/288 (45%), Gaps = 21/288 (7%)

Query: 34  PEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEG----QDQGSAY 89
           P DP++A VG + TL C  SPE   +   + + W  +     V  +  G    ++Q   Y
Sbjct: 35  PTDPILATVGENTTLRCHLSPEK--NAEDMEVRWFRSQFSPAVFVYKGGRERTEEQMEEY 92

Query: 90  ANRTALFPDLLAQGNASLRLQRVRVADEGSFTC-FVSIRDFGSAAVSLQVAAPYSKPSMT 148
             RT      +++G+ +L +  +   + G++ C F   R +  A + L VA   SKP ++
Sbjct: 93  RGRTTFVSKDISRGSVALVIHNITAQENGTYRCYFQEGRSYDEAILHLVVAGLGSKPLIS 152

Query: 149 LEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQG--VPLTGNVTTSQMANEQGLFDVHS 206
           +  ++D      + + C S   YP+    W+D  G   P    V+   M +  GLF V +
Sbjct: 153 MRGHED----GGIRLECISRGWYPKPLTVWRDPYGGVAPALKEVS---MPDADGLFMVTT 205

Query: 207 VLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIALLVAL 266
            + +   +    SC + N +L Q     + I   P +F P      V L + ++ L++ +
Sbjct: 206 AVIIRDKSVRNMSCSINNTLLGQKKESVIFI---PESFMPSVSPCAVALPIIVVILMIPI 262

Query: 267 AFVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPL-KHSDSKEDDGQ 313
           A VC   I +  +E+   + +++ E E  + AL+ L K    KE++ Q
Sbjct: 263 A-VCIYWINKLQKEKKILSGEKEFERETREIALKELEKERVQKEEELQ 309


>gi|17975772 butyrophilin, subfamily 2, member A1 isoform 2
           precursor [Homo sapiens]
          Length = 334

 Score = 80.9 bits (198), Expect = 1e-15
 Identities = 73/288 (25%), Positives = 131/288 (45%), Gaps = 21/288 (7%)

Query: 34  PEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEG----QDQGSAY 89
           P DP++A VG + TL C  SPE   +   + + W  +     V  +  G    ++Q   Y
Sbjct: 35  PTDPILATVGENTTLRCHLSPEK--NAEDMEVRWFRSQFSPAVFVYKGGRERTEEQMEEY 92

Query: 90  ANRTALFPDLLAQGNASLRLQRVRVADEGSFTC-FVSIRDFGSAAVSLQVAAPYSKPSMT 148
             RT      +++G+ +L +  +   + G++ C F   R +  A + L VA   SKP ++
Sbjct: 93  RGRTTFVSKDISRGSVALVIHNITAQENGTYRCYFQEGRSYDEAILHLVVAGLGSKPLIS 152

Query: 149 LEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQG--VPLTGNVTTSQMANEQGLFDVHS 206
           +  ++D      + + C S   YP+    W+D  G   P    V+   M +  GLF V +
Sbjct: 153 MRGHED----GGIRLECISRGWYPKPLTVWRDPYGGVAPALKEVS---MPDADGLFMVTT 205

Query: 207 VLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIALLVAL 266
            + +   +    SC + N +L Q     + I   P +F P      V L + ++ L++ +
Sbjct: 206 AVIIRDKSVRNMSCSINNTLLGQKKESVIFI---PESFMPSVSPCAVALPIIVVILMIPI 262

Query: 267 AFVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPL-KHSDSKEDDGQ 313
           A VC   I +  +E+   + +++ E E  + AL+ L K    KE++ Q
Sbjct: 263 A-VCIYWINKLQKEKKILSGEKEFERETREIALKELEKERVQKEEELQ 309


>gi|5901964 HERV-H LTR-associating 2 [Homo sapiens]
          Length = 414

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 63/220 (28%), Positives = 103/220 (46%), Gaps = 21/220 (9%)

Query: 23  FCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEG 82
           F L   + V + E  V+  +  D  L  SF  E G   +++ + W+  D+ + VHS+ +G
Sbjct: 24  FPLAFFIYVPMNEQIVIGRLDEDIILPSSF--ERG---SEVVIHWKYQDSYK-VHSYYKG 77

Query: 83  QD----QGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQV 138
            D    Q   YANRT+LF + +  GNASL  +RV + DEG +TC+V        A+ +  
Sbjct: 78  SDHLESQDPRYANRTSLFYNEIQNGNASLFFRRVSLLDEGIYTCYV------GTAIQVIT 131

Query: 139 AAPYSKPSMTLEPNKDLRPGDTVT-ITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMAN 197
                K  + L P       +T + + CS    YP   + W+     P++ N    +   
Sbjct: 132 NKVVLKVGVFLTPVMKYEKRNTNSFLICSVLSVYPRPIITWK-MDNTPISEN--NMEETG 188

Query: 198 EQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTI 237
               F ++S L +  G+N +Y C + N +L+Q   G  T+
Sbjct: 189 SLDSFSINSPLNIT-GSNSSYECTIENSLLKQTWTGRWTM 227


>gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo
           sapiens]
          Length = 523

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 64/235 (27%), Positives = 105/235 (44%), Gaps = 19/235 (8%)

Query: 34  PEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEG----QDQGSAY 89
           P +P++A+VG + TL C  SPE   +   + + W  +     V  +  G    ++Q   Y
Sbjct: 39  PANPILAMVGENTTLRCHLSPEK--NAEDMEVRWFRSQFSPAVFVYKGGRERTEEQMEEY 96

Query: 90  ANRTALFPDLLAQGNASLRLQRVRVADEGSFTC-FVSIRDFGSAAVSLQVAAPYSKPSMT 148
             R       + +G+ +L +  V   + G + C F   R +  A + L VA   SKP + 
Sbjct: 97  RGRITFVSKDINRGSVALVIHNVTAQENGIYRCYFQEGRSYDEAILRLVVAGLGSKPLIE 156

Query: 149 LEPNKDLRPGDTVTITCSSYRGYPEAEVFWQD--GQGVPLTGNVTTSQMANEQGLFDVHS 206
           ++  +D     ++ + C S   YPE    W+D  G+ VP    V+   +A+  GLF V +
Sbjct: 157 IKAQED----GSIWLECISGGWYPEPLTVWRDPYGEVVPALKEVS---IADADGLFMVTT 209

Query: 207 VLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIA 261
            + +        SC V N +L Q+     T+   P +F P A    V L+V L A
Sbjct: 210 AVIIRDKYVRNVSCSVNNTLLGQEKE---TVIFIPESFMPSASPWMVALAVILTA 261


>gi|190014605 programmed cell death 1 ligand 2 [Homo sapiens]
          Length = 273

 Score = 69.7 bits (169), Expect = 3e-12
 Identities = 68/256 (26%), Positives = 113/256 (44%), Gaps = 34/256 (13%)

Query: 31  VQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQGSAYA 90
           V VP++  +   G++ TL C+F      +L  +              S  + ++  S + 
Sbjct: 23  VTVPKELYIIEHGSNVTLECNFDTGSHVNLGAITA------------SLQKVENDTSPHR 70

Query: 91  NRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSA----AVSLQVAAPYSKPS 146
            R  L  + L  G AS  + +V+V DEG + C +    +G A     ++L+V A Y K +
Sbjct: 71  ERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIII---YGVAWDYKYLTLKVKASYRKIN 127

Query: 147 MTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHS 206
             +     +   D V +TC +  GYP AEV W +   VP      TS     +GL+ V S
Sbjct: 128 THI---LKVPETDEVELTCQA-TGYPLAEVSWPN-VSVP----ANTSHSRTPEGLYQVTS 178

Query: 207 VLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQ--PMTFPPEALWVTVGLSVCLIALLV 264
           VLR+       +SC+  N  +++    S+ +  Q  P T P   L + +    C+IA + 
Sbjct: 179 VLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPTWLLHIFI--PFCIIAFIF 236

Query: 265 ALAFVCWRKIKQSCEE 280
               +  R  KQ C++
Sbjct: 237 IATVIALR--KQLCQK 250


>gi|56788393 myelin oligodendrocyte glycoprotein isoform beta5
           precursor [Homo sapiens]
          Length = 213

 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 41/121 (33%), Positives = 60/121 (49%), Gaps = 7/121 (5%)

Query: 27  GALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQG 86
           G   V  P  P+ ALVG +  L C  SP  G +   + + W      ++VH +  G+DQ 
Sbjct: 30  GQFRVIGPRHPIRALVGDEVELPCRISP--GKNATGMEVGWYRPPFSRVVHLYRNGKDQD 87

Query: 87  S----AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAP 141
                 Y  RT L  D + +G  +LR++ VR +DEG FTCF     +   AA+ L+V  P
Sbjct: 88  GDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKVEDP 147

Query: 142 Y 142
           +
Sbjct: 148 F 148


>gi|56788391 myelin oligodendrocyte glycoprotein isoform beta2
           precursor [Homo sapiens]
          Length = 206

 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 41/121 (33%), Positives = 60/121 (49%), Gaps = 7/121 (5%)

Query: 27  GALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQG 86
           G   V  P  P+ ALVG +  L C  SP  G +   + + W      ++VH +  G+DQ 
Sbjct: 30  GQFRVIGPRHPIRALVGDEVELPCRISP--GKNATGMEVGWYRPPFSRVVHLYRNGKDQD 87

Query: 87  S----AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAP 141
                 Y  RT L  D + +G  +LR++ VR +DEG FTCF     +   AA+ L+V  P
Sbjct: 88  GDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKVEDP 147

Query: 142 Y 142
           +
Sbjct: 148 F 148


>gi|56788389 myelin oligodendrocyte glycoprotein isoform alpha3
           precursor [Homo sapiens]
          Length = 224

 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 41/121 (33%), Positives = 60/121 (49%), Gaps = 7/121 (5%)

Query: 27  GALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQG 86
           G   V  P  P+ ALVG +  L C  SP  G +   + + W      ++VH +  G+DQ 
Sbjct: 30  GQFRVIGPRHPIRALVGDEVELPCRISP--GKNATGMEVGWYRPPFSRVVHLYRNGKDQD 87

Query: 87  S----AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAP 141
                 Y  RT L  D + +G  +LR++ VR +DEG FTCF     +   AA+ L+V  P
Sbjct: 88  GDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKVEDP 147

Query: 142 Y 142
           +
Sbjct: 148 F 148


>gi|56788387 myelin oligodendrocyte glycoprotein isoform beta3
           precursor [Homo sapiens]
          Length = 229

 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 41/121 (33%), Positives = 60/121 (49%), Gaps = 7/121 (5%)

Query: 27  GALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQG 86
           G   V  P  P+ ALVG +  L C  SP  G +   + + W      ++VH +  G+DQ 
Sbjct: 30  GQFRVIGPRHPIRALVGDEVELPCRISP--GKNATGMEVGWYRPPFSRVVHLYRNGKDQD 87

Query: 87  S----AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAP 141
                 Y  RT L  D + +G  +LR++ VR +DEG FTCF     +   AA+ L+V  P
Sbjct: 88  GDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKVEDP 147

Query: 142 Y 142
           +
Sbjct: 148 F 148


>gi|56788385 myelin oligodendrocyte glycoprotein isoform beta1
           precursor [Homo sapiens]
          Length = 252

 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 41/121 (33%), Positives = 60/121 (49%), Gaps = 7/121 (5%)

Query: 27  GALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQG 86
           G   V  P  P+ ALVG +  L C  SP  G +   + + W      ++VH +  G+DQ 
Sbjct: 30  GQFRVIGPRHPIRALVGDEVELPCRISP--GKNATGMEVGWYRPPFSRVVHLYRNGKDQD 87

Query: 87  S----AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAP 141
                 Y  RT L  D + +G  +LR++ VR +DEG FTCF     +   AA+ L+V  P
Sbjct: 88  GDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKVEDP 147

Query: 142 Y 142
           +
Sbjct: 148 F 148


>gi|56788383 myelin oligodendrocyte glycoprotein isoform alpha2
           precursor [Homo sapiens]
          Length = 208

 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 41/121 (33%), Positives = 60/121 (49%), Gaps = 7/121 (5%)

Query: 27  GALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQG 86
           G   V  P  P+ ALVG +  L C  SP  G +   + + W      ++VH +  G+DQ 
Sbjct: 30  GQFRVIGPRHPIRALVGDEVELPCRISP--GKNATGMEVGWYRPPFSRVVHLYRNGKDQD 87

Query: 87  S----AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAP 141
                 Y  RT L  D + +G  +LR++ VR +DEG FTCF     +   AA+ L+V  P
Sbjct: 88  GDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKVEDP 147

Query: 142 Y 142
           +
Sbjct: 148 F 148


>gi|56788381 myelin oligodendrocyte glycoprotein isoform alpha1
           precursor [Homo sapiens]
          Length = 247

 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 41/121 (33%), Positives = 60/121 (49%), Gaps = 7/121 (5%)

Query: 27  GALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQG 86
           G   V  P  P+ ALVG +  L C  SP  G +   + + W      ++VH +  G+DQ 
Sbjct: 30  GQFRVIGPRHPIRALVGDEVELPCRISP--GKNATGMEVGWYRPPFSRVVHLYRNGKDQD 87

Query: 87  S----AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAP 141
                 Y  RT L  D + +G  +LR++ VR +DEG FTCF     +   AA+ L+V  P
Sbjct: 88  GDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKVEDP 147

Query: 142 Y 142
           +
Sbjct: 148 F 148


>gi|56788397 myelin oligodendrocyte glycoprotein isoform beta4
           precursor [Homo sapiens]
          Length = 171

 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 41/122 (33%), Positives = 60/122 (49%), Gaps = 7/122 (5%)

Query: 27  GALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQG 86
           G   V  P  P+ ALVG +  L C  SP  G +   + + W      ++VH +  G+DQ 
Sbjct: 30  GQFRVIGPRHPIRALVGDEVELPCRISP--GKNATGMEVGWYRPPFSRVVHLYRNGKDQD 87

Query: 87  S----AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAP 141
                 Y  RT L  D + +G  +LR++ VR +DEG FTCF     +   AA+ L+V   
Sbjct: 88  GDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKVEVS 147

Query: 142 YS 143
           +S
Sbjct: 148 HS 149


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,131,186
Number of Sequences: 37866
Number of extensions: 599224
Number of successful extensions: 2926
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 100
Number of HSP's successfully gapped in prelim test: 242
Number of HSP's that attempted gapping in prelim test: 2244
Number of HSP's gapped (non-prelim): 758
length of query: 316
length of database: 18,247,518
effective HSP length: 102
effective length of query: 214
effective length of database: 14,385,186
effective search space: 3078429804
effective search space used: 3078429804
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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