Search of human proteins with 51491914

Search of human proteins with 51491914

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|51491914 dual specificity phosphatase and pro isomerase
domain containing 1 [Homo sapiens]
         (220 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|51491914 dual specificity phosphatase and pro isomerase domai...   451   e-127
gi|56237018 testis and skeletal muscle-specific dual specificity...   181   4e-46
gi|56117822 testis and skeletal muscle-specific dual specificity...   181   4e-46
gi|56117820 testis and skeletal muscle-specific dual specificity...   181   4e-46
gi|13128968 dual specificity phosphatase 26 [Homo sapiens]            175   3e-44
gi|56117818 muscle-restricted dual specificity phosphatase isofo...   169   1e-42
gi|122937243 dual specificity phosphatase 27 [Homo sapiens]           160   8e-40
gi|4758208 dual specificity phosphatase 3 [Homo sapiens]              135   4e-32
gi|9910432 dual specificity phosphatase 22 [Homo sapiens]              77   9e-15
gi|4503421 dual specificity phosphatase 9 [Homo sapiens]               77   1e-14
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]     75   3e-14
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]    75   3e-14
gi|239047414 slingshot 1 isoform 1 [Homo sapiens]                      73   2e-13
gi|239047498 slingshot 1 isoform 3 [Homo sapiens]                      73   2e-13
gi|239047441 slingshot 1 isoform 2 [Homo sapiens]                      73   2e-13
gi|4758206 dual specificity phosphatase 2 [Homo sapiens]               71   8e-13
gi|239582767 slingshot homolog 3 [Homo sapiens]                        69   2e-12
gi|5902002 dual specificity phosphatase 14 [Homo sapiens]              68   5e-12
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi...    68   7e-12
gi|38372911 dual specificity phosphatase 16 [Homo sapiens]             67   9e-12
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]    67   1e-11
gi|4758204 dual specificity phosphatase 1 [Homo sapiens]               65   3e-11
gi|51093845 dual specificity phosphatase 18 [Homo sapiens]             65   5e-11
gi|37674210 slingshot 2 [Homo sapiens]                                 64   8e-11
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ...    63   2e-10
gi|194733759 serine/threonine/tyrosine interacting protein [Homo...    63   2e-10
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ...    63   2e-10
gi|238231453 dual specificity phosphatase 7 [Homo sapiens]             62   4e-10
gi|62865890 dual specificity phosphatase 5 [Homo sapiens]              62   5e-10
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]    61   7e-10

>gi|51491914 dual specificity phosphatase and pro isomerase domain
           containing 1 [Homo sapiens]
          Length = 220

 Score =  451 bits (1161), Expect = e-127
 Identities = 220/220 (100%), Positives = 220/220 (100%)

Query: 1   MTSGEVKTSLKNAYSSAKRLSPKMEEEGEEEDYCTPGAFELERLFWKGSPQYTHVNEVWP 60
           MTSGEVKTSLKNAYSSAKRLSPKMEEEGEEEDYCTPGAFELERLFWKGSPQYTHVNEVWP
Sbjct: 1   MTSGEVKTSLKNAYSSAKRLSPKMEEEGEEEDYCTPGAFELERLFWKGSPQYTHVNEVWP 60

Query: 61  KLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDLPTFD 120
           KLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDLPTFD
Sbjct: 61  KLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDLPTFD 120

Query: 121 LSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKN 180
           LSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKN
Sbjct: 121 LSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKN 180

Query: 181 RCVLPNRGFLKQLRELDKQLVQQRRRSQRQDGEEEDGREL 220
           RCVLPNRGFLKQLRELDKQLVQQRRRSQRQDGEEEDGREL
Sbjct: 181 RCVLPNRGFLKQLRELDKQLVQQRRRSQRQDGEEEDGREL 220


>gi|56237018 testis and skeletal muscle-specific dual specificity
           phosphatase isoform 6 [Homo sapiens]
          Length = 198

 Score =  181 bits (459), Expect = 4e-46
 Identities = 91/186 (48%), Positives = 126/186 (67%), Gaps = 1/186 (0%)

Query: 22  PKMEEEGEEEDYCTPGAFELERLFW-KGSPQYTHVNEVWPKLYIGDEATALDRYRLQKAG 80
           PK+    +   Y  P    L+RL W + +    H++EVWP L++GD   A D+ +L + G
Sbjct: 12  PKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLG 71

Query: 81  FTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDLPTFDLSVFFYPAAAFIDRALSDDH 140
            THV+NAA G++ VDTG  +YR M ++Y+G+EADD P FDLSV+F P A +I  ALS   
Sbjct: 72  ITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQ 131

Query: 141 SKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKNRCVLPNRGFLKQLRELDKQL 200
            ++LVHC MG SRSATLVLA+LMI ++MTLV+AIQ V  +R + PN GFL+QL+ LD +L
Sbjct: 132 GRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRL 191

Query: 201 VQQRRR 206
            ++  R
Sbjct: 192 GRETGR 197


>gi|56117822 testis and skeletal muscle-specific dual specificity
           phosphatase isoform 3 [Homo sapiens]
          Length = 291

 Score =  181 bits (459), Expect = 4e-46
 Identities = 91/186 (48%), Positives = 126/186 (67%), Gaps = 1/186 (0%)

Query: 22  PKMEEEGEEEDYCTPGAFELERLFW-KGSPQYTHVNEVWPKLYIGDEATALDRYRLQKAG 80
           PK+    +   Y  P    L+RL W + +    H++EVWP L++GD   A D+ +L + G
Sbjct: 105 PKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLG 164

Query: 81  FTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDLPTFDLSVFFYPAAAFIDRALSDDH 140
            THV+NAA G++ VDTG  +YR M ++Y+G+EADD P FDLSV+F P A +I  ALS   
Sbjct: 165 ITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQ 224

Query: 141 SKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKNRCVLPNRGFLKQLRELDKQL 200
            ++LVHC MG SRSATLVLA+LMI ++MTLV+AIQ V  +R + PN GFL+QL+ LD +L
Sbjct: 225 GRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRL 284

Query: 201 VQQRRR 206
            ++  R
Sbjct: 285 GRETGR 290


>gi|56117820 testis and skeletal muscle-specific dual specificity
           phosphatase isoform 2 [Homo sapiens]
          Length = 248

 Score =  181 bits (459), Expect = 4e-46
 Identities = 91/186 (48%), Positives = 126/186 (67%), Gaps = 1/186 (0%)

Query: 22  PKMEEEGEEEDYCTPGAFELERLFW-KGSPQYTHVNEVWPKLYIGDEATALDRYRLQKAG 80
           PK+    +   Y  P    L+RL W + +    H++EVWP L++GD   A D+ +L + G
Sbjct: 62  PKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLG 121

Query: 81  FTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDLPTFDLSVFFYPAAAFIDRALSDDH 140
            THV+NAA G++ VDTG  +YR M ++Y+G+EADD P FDLSV+F P A +I  ALS   
Sbjct: 122 ITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQ 181

Query: 141 SKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKNRCVLPNRGFLKQLRELDKQL 200
            ++LVHC MG SRSATLVLA+LMI ++MTLV+AIQ V  +R + PN GFL+QL+ LD +L
Sbjct: 182 GRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRL 241

Query: 201 VQQRRR 206
            ++  R
Sbjct: 242 GRETGR 247



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 19/51 (37%), Positives = 28/51 (54%)

Query: 28 GEEEDYCTPGAFELERLFWKGSPQYTHVNEVWPKLYIGDEATALDRYRLQK 78
          GE++    P   ELE L   G    + V+EVWP L+IGD   +L +  L++
Sbjct: 11 GEDKATPCPSILELEELLRAGKSSCSRVDEVWPNLFIGDAMDSLQKQDLRR 61


>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
          Length = 211

 Score =  175 bits (443), Expect = 3e-44
 Identities = 89/164 (54%), Positives = 115/164 (70%), Gaps = 2/164 (1%)

Query: 39  FELERLFWKGSPQYTHVNEVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGP 98
           FELERL + G     H +EVWP LY+GD+  A +R  L++ G THVLNA+H RW     P
Sbjct: 46  FELERLLYTGKTACNHADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGT--P 103

Query: 99  DYYRDMDIQYHGVEADDLPTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLV 158
           + Y  + I+Y GVEA D P FD+S+ F  AA FI RALS    KILVHC +G SRSATLV
Sbjct: 104 EAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLV 163

Query: 159 LAYLMIHKDMTLVDAIQQVAKNRCVLPNRGFLKQLRELDKQLVQ 202
           LAYLM++  +TLV+AI++V  +R ++PNRGFL+QL  LD++L Q
Sbjct: 164 LAYLMLYHHLTLVEAIKKVKDHRGIIPNRGFLRQLLALDRRLRQ 207


>gi|56117818 muscle-restricted dual specificity phosphatase isoform
           1 [Homo sapiens]
          Length = 188

 Score =  169 bits (429), Expect = 1e-42
 Identities = 91/173 (52%), Positives = 114/173 (65%), Gaps = 1/173 (0%)

Query: 28  GEEEDYCTPGAFELERLFWKGSPQYTHVNEVWPKLYIGDEATALDRYRLQKAGFTHVLNA 87
           GE++    P   ELE L   G    + V+EVWP L+IGD ATA +R+ L K G THVLNA
Sbjct: 11  GEDKATPCPSILELEELLRAGKSSCSRVDEVWPNLFIGDAATANNRFELWKLGITHVLNA 70

Query: 88  AHGRWNVDTGPDYYRDMDIQYHGVEADDLPTFDLSVFFYPAAAFIDRALSDDHSKILVHC 147
           AH       GPD+Y    + Y GV A DLP FD+S +F  AA FI RAL+   +K+LVHC
Sbjct: 71  AHKGLYCQGGPDFYGS-SVSYLGVPAHDLPDFDISAYFSSAADFIHRALNTPGAKVLVHC 129

Query: 148 VMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKNRCVLPNRGFLKQLRELDKQL 200
           V+G SRSATLVLAYLM+H+ ++L  A+  V ++R V PNRGFL QL  LD+QL
Sbjct: 130 VVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHRWVFPNRGFLHQLCRLDQQL 182


>gi|122937243 dual specificity phosphatase 27 [Homo sapiens]
          Length = 1158

 Score =  160 bits (405), Expect = 8e-40
 Identities = 81/189 (42%), Positives = 122/189 (64%), Gaps = 3/189 (1%)

Query: 33  YCTPGAFELERLFWKGSPQ--YTHVNEVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHG 90
           Y TP   +L+R   +   +  +  V+EVWP ++I +++ A+++ RL++ G TH+LNAAHG
Sbjct: 110 YNTPCVLDLQRALVQDRQEAPWNEVDEVWPNVFIAEKSVAVNKGRLKRLGITHILNAAHG 169

Query: 91  RWNVDTGPDYYRDMDIQYHGVEADDLPTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMG 150
              V TGP++Y  ++IQY GVE DD P  D+S  F  A+ F+D AL     K+LV   MG
Sbjct: 170 T-GVYTGPEFYTGLEIQYLGVEVDDFPEVDISQHFRKASEFLDEALLTYRGKVLVSSEMG 228

Query: 151 RSRSATLVLAYLMIHKDMTLVDAIQQVAKNRCVLPNRGFLKQLRELDKQLVQQRRRSQRQ 210
            SRSA LV+AYLMI  +M +++A+  V K R + PN GFLKQLREL+++L+++R     +
Sbjct: 229 ISRSAVLVVAYLMIFHNMAILEALMTVRKKRAIYPNEGFLKQLRELNEKLMEEREEDYGR 288

Query: 211 DGEEEDGRE 219
           +G   +  E
Sbjct: 289 EGGSAEAEE 297


>gi|4758208 dual specificity phosphatase 3 [Homo sapiens]
          Length = 185

 Score =  135 bits (339), Expect = 4e-32
 Identities = 70/150 (46%), Positives = 103/150 (68%), Gaps = 2/150 (1%)

Query: 56  NEVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGR--WNVDTGPDYYRDMDIQYHGVEA 113
           NEV P++Y+G+ + A D  +LQK G THVLNAA GR   +V+T  ++Y+D  I Y G++A
Sbjct: 31  NEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKA 90

Query: 114 DDLPTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDA 173
           +D   F+LS +F  AA FID+AL+  + ++LVHC  G SRS TLV+AYLM+ + M +  A
Sbjct: 91  NDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSA 150

Query: 174 IQQVAKNRCVLPNRGFLKQLRELDKQLVQQ 203
           +  V +NR + PN GFL QL +L+ +L ++
Sbjct: 151 LSIVRQNREIGPNDGFLAQLCQLNDRLAKE 180


>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
          Length = 184

 Score = 77.4 bits (189), Expect = 9e-15
 Identities = 59/169 (34%), Positives = 82/169 (48%), Gaps = 18/169 (10%)

Query: 55  VNEVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEAD 114
           +N++ P LYIG+   A D  +L K   TH+L+       +  G        ++Y  + A 
Sbjct: 5   MNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEG--------VKYLCIPAA 56

Query: 115 DLPTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAI 174
           D P+ +L+  F  +  FI        S  LVHC+ G SRS TLV+AY+M   D    DA+
Sbjct: 57  DSPSQNLTRHFKESIKFIHECRLRGES-CLVHCLAGVSRSVTLVIAYIMTVTDFGWEDAL 115

Query: 175 QQVAKNR-CVLPNRGFLKQLRELDKQLVQQRRR--------SQRQDGEE 214
             V   R C  PN GF +QL+E +K  V Q R+        S  QD EE
Sbjct: 116 HTVRAGRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEE 164


>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
          Length = 384

 Score = 77.0 bits (188), Expect = 1e-14
 Identities = 51/155 (32%), Positives = 79/155 (50%), Gaps = 7/155 (4%)

Query: 57  EVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDL 116
           ++ P LY+G    + +   L K G  ++LN      N      + ++ D  Y  +   D 
Sbjct: 206 QILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNF-----FEKNGDFHYKQIPISDH 260

Query: 117 PTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQ 176
            + +LS FF  A  FID ALS +   +LVHC+ G SRS T+ +AYLM    ++L DA   
Sbjct: 261 WSQNLSRFFPEAIEFIDEALSQNCG-VLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDL 319

Query: 177 VAKNRC-VLPNRGFLKQLRELDKQLVQQRRRSQRQ 210
           V + +  + PN  F+ QL + ++ L  + R SQ Q
Sbjct: 320 VKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQ 354


>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
          Length = 394

 Score = 75.5 bits (184), Expect = 3e-14
 Identities = 50/146 (34%), Positives = 78/146 (53%), Gaps = 9/146 (6%)

Query: 57  EVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDL 116
           E+ P LY+G    A  R  L   G T +LN +         P+++     QY  +  +D 
Sbjct: 198 EILPFLYLGSAYHAARRDMLDALGITALLNVS------SDCPNHFEG-HYQYKCIPVEDN 250

Query: 117 PTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQ 176
              D+S +F  A  +ID A+ D   ++LVHC  G SRSAT+ LAYLM+ K + L +A + 
Sbjct: 251 HKADISSWFMEAIEYID-AVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEF 309

Query: 177 VAKNRCVL-PNRGFLKQLRELDKQLV 201
           V + R ++ PN  F+ QL + + Q++
Sbjct: 310 VKQRRSIISPNFSFMGQLLQFESQVL 335


>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
          Length = 303

 Score = 75.5 bits (184), Expect = 3e-14
 Identities = 50/146 (34%), Positives = 78/146 (53%), Gaps = 9/146 (6%)

Query: 57  EVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDL 116
           E+ P LY+G    A  R  L   G T +LN +         P+++     QY  +  +D 
Sbjct: 107 EILPFLYLGSAYHAARRDMLDALGITALLNVS------SDCPNHFEG-HYQYKCIPVEDN 159

Query: 117 PTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQ 176
              D+S +F  A  +ID A+ D   ++LVHC  G SRSAT+ LAYLM+ K + L +A + 
Sbjct: 160 HKADISSWFMEAIEYID-AVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEF 218

Query: 177 VAKNRCVL-PNRGFLKQLRELDKQLV 201
           V + R ++ PN  F+ QL + + Q++
Sbjct: 219 VKQRRSIISPNFSFMGQLLQFESQVL 244


>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
          Length = 1049

 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 53/160 (33%), Positives = 77/160 (48%), Gaps = 9/160 (5%)

Query: 58  VWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDLP 117
           ++  LY+G E  A +   LQ +G  ++LN      N   G          YH +   D  
Sbjct: 312 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGL-------FAYHNIRVYDEE 364

Query: 118 TFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQV 177
           T DL   +  A  FI++A   +HSK LVHC MG SRSA+ V+AY M      L  A   V
Sbjct: 365 TTDLLAHWNEAYHFINKA-KRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYV 423

Query: 178 AKNRCVL-PNRGFLKQLRELDKQLVQQRRRSQRQDGEEED 216
            + R +  PN GF++QL E +  L   ++R  +   ++ D
Sbjct: 424 KQKRSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTD 463


>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
          Length = 703

 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 53/160 (33%), Positives = 77/160 (48%), Gaps = 9/160 (5%)

Query: 58  VWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDLP 117
           ++  LY+G E  A +   LQ +G  ++LN      N   G          YH +   D  
Sbjct: 323 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGL-------FAYHNIRVYDEE 375

Query: 118 TFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQV 177
           T DL   +  A  FI++A   +HSK LVHC MG SRSA+ V+AY M      L  A   V
Sbjct: 376 TTDLLAHWNEAYHFINKA-KRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYV 434

Query: 178 AKNRCVL-PNRGFLKQLRELDKQLVQQRRRSQRQDGEEED 216
            + R +  PN GF++QL E +  L   ++R  +   ++ D
Sbjct: 435 KQKRSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTD 474


>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
          Length = 692

 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 53/160 (33%), Positives = 77/160 (48%), Gaps = 9/160 (5%)

Query: 58  VWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDLP 117
           ++  LY+G E  A +   LQ +G  ++LN      N   G          YH +   D  
Sbjct: 312 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGL-------FAYHNIRVYDEE 364

Query: 118 TFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQV 177
           T DL   +  A  FI++A   +HSK LVHC MG SRSA+ V+AY M      L  A   V
Sbjct: 365 TTDLLAHWNEAYHFINKA-KRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYV 423

Query: 178 AKNRCVL-PNRGFLKQLRELDKQLVQQRRRSQRQDGEEED 216
            + R +  PN GF++QL E +  L   ++R  +   ++ D
Sbjct: 424 KQKRSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTD 463


>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
          Length = 314

 Score = 70.9 bits (172), Expect = 8e-13
 Identities = 47/146 (32%), Positives = 79/146 (54%), Gaps = 9/146 (6%)

Query: 57  EVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDL 116
           E+ P L++G  + + D   LQ  G T VLN +       + P+++  +  +Y  +  +D 
Sbjct: 175 EILPYLFLGSCSHSSDLQGLQACGITAVLNVSA------SCPNHFEGL-FRYKSIPVEDN 227

Query: 117 PTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQ 176
              ++S +F  A  FID  + +   ++LVHC  G SRSAT+ LAYLM  + + L +A   
Sbjct: 228 QMVEISAWFQEAIGFIDW-VKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDF 286

Query: 177 VAKNRCVL-PNRGFLKQLRELDKQLV 201
           V + R V+ PN  F+ QL + + Q++
Sbjct: 287 VKQRRGVISPNFSFMGQLLQFETQVL 312


>gi|239582767 slingshot homolog 3 [Homo sapiens]
          Length = 659

 Score = 69.3 bits (168), Expect = 2e-12
 Identities = 50/145 (34%), Positives = 75/145 (51%), Gaps = 9/145 (6%)

Query: 51  QYTHVNEVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHG 110
           Q    + ++P LY+G E  A +   LQ+   TH+LN A     +D   ++Y +    YH 
Sbjct: 325 QRDRASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAR---EID---NFYPER-FTYHN 377

Query: 111 VEADDLPTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTL 170
           V   D  +  L   +     FI+ A +   + +LVHC MG SRSA  VLAY M   + +L
Sbjct: 378 VRLWDEESAQLLPHWKETHRFIEAARAQG-THVLVHCKMGVSRSAATVLAYAMKQYECSL 436

Query: 171 VDAIQQVAKNRCVL-PNRGFLKQLR 194
             A++ V + R +  PN GFL+QL+
Sbjct: 437 EQALRHVQELRPIARPNPGFLRQLQ 461


>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
          Length = 198

 Score = 68.2 bits (165), Expect = 5e-12
 Identities = 49/147 (33%), Positives = 78/147 (53%), Gaps = 9/147 (6%)

Query: 55  VNEVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEAD 114
           + ++   L++G  + A +R+ LQ  G T ++NA     N +  P +      +Y  V   
Sbjct: 27  IAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNW-PQF------EYVKVPLA 79

Query: 115 DLPTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAI 174
           D+P   + ++F   A  I  ++S  H   LVHC  G SRSATL +AYLM   ++ L++A 
Sbjct: 80  DMPHAPIGLYFDTVADKI-HSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAY 138

Query: 175 QQVAKNRCVL-PNRGFLKQLRELDKQL 200
             V   R V+ PN GF +QL + ++QL
Sbjct: 139 NWVKARRPVIRPNVGFWRQLIDYERQL 165


>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
           sapiens]
          Length = 217

 Score = 67.8 bits (164), Expect = 7e-12
 Identities = 50/163 (30%), Positives = 76/163 (46%), Gaps = 14/163 (8%)

Query: 55  VNEVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEAD 114
           V  + P L +G +  A D   L+K   TH+LN A+G  N           D  Y  +   
Sbjct: 66  VGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLS-------DFTYKSISIL 118

Query: 115 DLPTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAI 174
           DLP  ++  +F     FI+ A   D   +LVHC  G SR+A +V+ +LM  +  +   A 
Sbjct: 119 DLPETNILSYFPECFEFIEEAKRKD-GVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAF 177

Query: 175 QQVAKNR-CVLPNRGFLKQLRELDKQLVQQRRRSQRQDGEEED 216
             V   R  + PN GF++QLR       Q+ + S + D  +E+
Sbjct: 178 SLVKNARPSICPNSGFMEQLR-----TYQEGKESNKCDRIQEN 215


>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
          Length = 665

 Score = 67.4 bits (163), Expect = 9e-12
 Identities = 51/153 (33%), Positives = 82/153 (53%), Gaps = 20/153 (13%)

Query: 58  VWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADD-- 115
           + P LY+G +   L++  +Q+ G  +VLNA+    N    PD+  +    +  V  +D  
Sbjct: 162 ILPNLYLGCQRDVLNKELMQQNGIGYVLNAS----NTCPKPDFIPES--HFLRVPVNDSF 215

Query: 116 ----LPTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLV 171
               LP  D SV       FI++A + +   +LVHC+ G SRSAT+ +AY+M   DM+L 
Sbjct: 216 CEKILPWLDKSV------DFIEKAKASNGC-VLVHCLAGISRSATIAIAYIMKRMDMSLD 268

Query: 172 DAIQQVAKNR-CVLPNRGFLKQLRELDKQLVQQ 203
           +A + V + R  + PN  FL QL + +K++  Q
Sbjct: 269 EAYRFVKEKRPTISPNFNFLGQLLDYEKKIKNQ 301


>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
          Length = 482

 Score = 67.0 bits (162), Expect = 1e-11
 Identities = 48/145 (33%), Positives = 74/145 (51%), Gaps = 9/145 (6%)

Query: 58  VWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDI-QYHGVEADDL 116
           + P L++G+E  A D   +Q+    +V+N           P Y+ +  +  Y  + A D 
Sbjct: 325 ILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHL------PLYHYEKGLFNYKRLPATDS 378

Query: 117 PTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQ 176
              +L  +F  A  FI+ A       +L+HC  G SRSAT+V+AYLM H  MT+ DA + 
Sbjct: 379 NKQNLRQYFEEAFEFIEEAHQCGKG-LLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKF 437

Query: 177 VAKNRCVL-PNRGFLKQLRELDKQL 200
           V   R ++ PN  F+ QL E ++ L
Sbjct: 438 VKGKRPIISPNLNFMGQLLEFEEDL 462


>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
          Length = 367

 Score = 65.5 bits (158), Expect = 3e-11
 Identities = 46/146 (31%), Positives = 73/146 (50%), Gaps = 9/146 (6%)

Query: 57  EVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDL 116
           E+ P LY+G    A  +  L   G T ++N +    N   G         QY  +  +D 
Sbjct: 176 EILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEG-------HYQYKSIPVEDN 228

Query: 117 PTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQ 176
              D+S +F  A  FID ++ +   ++ VHC  G SRSAT+ LAYLM    + L +A + 
Sbjct: 229 HKADISSWFNEAIDFID-SIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEF 287

Query: 177 VAKNRCVL-PNRGFLKQLRELDKQLV 201
           V + R ++ PN  F+ QL + + Q++
Sbjct: 288 VKQRRSIISPNFSFMGQLLQFESQVL 313


>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
          Length = 188

 Score = 65.1 bits (157), Expect = 5e-11
 Identities = 51/152 (33%), Positives = 73/152 (48%), Gaps = 9/152 (5%)

Query: 50  PQYTHVNEVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYH 109
           P  + ++++   LYI +   A ++  L     T V+N +     V+     Y D  IQY 
Sbjct: 15  PSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVS-----VEVVNTLYED--IQYM 67

Query: 110 GVEADDLPTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMT 169
            V   D P   L  FF P A  I  ++     + L+HC  G SRSA L LAYLM +  M+
Sbjct: 68  QVPVADSPNSRLCDFFDPIADHI-HSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMS 126

Query: 170 LVDAIQQVAKNRCVL-PNRGFLKQLRELDKQL 200
           L+DA       R ++ PN GF +QL   + QL
Sbjct: 127 LLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQL 158


>gi|37674210 slingshot 2 [Homo sapiens]
          Length = 1423

 Score = 64.3 bits (155), Expect = 8e-11
 Identities = 47/154 (30%), Positives = 70/154 (45%), Gaps = 9/154 (5%)

Query: 57  EVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDL 116
           +++  +++G E  A +   LQ  G  ++LN      N   G         +YH +   D 
Sbjct: 310 QIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGV-------FEYHNIRVYDE 362

Query: 117 PTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQ 176
              DL  ++     FI +A     SK LVHC MG SRSA+ V+AY M      L  A   
Sbjct: 363 EATDLLAYWNDTYKFISKAKKHG-SKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDY 421

Query: 177 VAKNRCVL-PNRGFLKQLRELDKQLVQQRRRSQR 209
           V + R V  PN  F++QL E    L+  ++R  +
Sbjct: 422 VKERRTVTKPNPSFMRQLEEYQGILLASKQRHNK 455


>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
           sapiens]
          Length = 223

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 55/182 (30%), Positives = 86/182 (47%), Gaps = 28/182 (15%)

Query: 22  PKMEEEGEEEDYCTPGAFELERLFWKGSPQYTHVNEVWPKLYIGDEATALDRYR--LQKA 79
           P+ +E+ EE  Y                P    + E+ P L++G  ++A+      LQK 
Sbjct: 12  PQCKEDAEEWTY----------------PMRREMQEILPGLFLGPYSSAMKSKLPVLQKH 55

Query: 80  GFTHVLNAAHGRWNVDTG---PDYYRDMDIQYHGVEADDLPTFDLSVFFYPAAAFIDRAL 136
           G TH++     R N++     P++ +    +Y  ++  D P  ++  FF     FID +L
Sbjct: 56  GITHIICI---RQNIEANFIKPNFQQLF--RYLVLDIADNPVENIIRFFPMTKEFIDGSL 110

Query: 137 SDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKNR-CVLPNRGFLKQLRE 195
                K+LVH   G SRSA  V+AY+M    M   DA   V + R C+ PN GF+ QL+E
Sbjct: 111 QMG-GKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQE 169

Query: 196 LD 197
            +
Sbjct: 170 YE 171


>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
           sapiens]
          Length = 223

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 55/182 (30%), Positives = 86/182 (47%), Gaps = 28/182 (15%)

Query: 22  PKMEEEGEEEDYCTPGAFELERLFWKGSPQYTHVNEVWPKLYIGDEATALDRYR--LQKA 79
           P+ +E+ EE  Y                P    + E+ P L++G  ++A+      LQK 
Sbjct: 12  PQCKEDAEEWTY----------------PMRREMQEILPGLFLGPYSSAMKSKLPVLQKH 55

Query: 80  GFTHVLNAAHGRWNVDTG---PDYYRDMDIQYHGVEADDLPTFDLSVFFYPAAAFIDRAL 136
           G TH++     R N++     P++ +    +Y  ++  D P  ++  FF     FID +L
Sbjct: 56  GITHIICI---RQNIEANFIKPNFQQLF--RYLVLDIADNPVENIIRFFPMTKEFIDGSL 110

Query: 137 SDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKNR-CVLPNRGFLKQLRE 195
                K+LVH   G SRSA  V+AY+M    M   DA   V + R C+ PN GF+ QL+E
Sbjct: 111 QMG-GKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQE 169

Query: 196 LD 197
            +
Sbjct: 170 YE 171


>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
           sapiens]
          Length = 223

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 55/182 (30%), Positives = 86/182 (47%), Gaps = 28/182 (15%)

Query: 22  PKMEEEGEEEDYCTPGAFELERLFWKGSPQYTHVNEVWPKLYIGDEATALDRYR--LQKA 79
           P+ +E+ EE  Y                P    + E+ P L++G  ++A+      LQK 
Sbjct: 12  PQCKEDAEEWTY----------------PMRREMQEILPGLFLGPYSSAMKSKLPVLQKH 55

Query: 80  GFTHVLNAAHGRWNVDTG---PDYYRDMDIQYHGVEADDLPTFDLSVFFYPAAAFIDRAL 136
           G TH++     R N++     P++ +    +Y  ++  D P  ++  FF     FID +L
Sbjct: 56  GITHIICI---RQNIEANFIKPNFQQLF--RYLVLDIADNPVENIIRFFPMTKEFIDGSL 110

Query: 137 SDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKNR-CVLPNRGFLKQLRE 195
                K+LVH   G SRSA  V+AY+M    M   DA   V + R C+ PN GF+ QL+E
Sbjct: 111 QMG-GKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQE 169

Query: 196 LD 197
            +
Sbjct: 170 YE 171


>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
          Length = 419

 Score = 62.0 bits (149), Expect = 4e-10
 Identities = 45/145 (31%), Positives = 72/145 (49%), Gaps = 7/145 (4%)

Query: 57  EVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDL 116
           ++ P LY+G    + +   L K G  ++LN      N      +    +  Y  +   D 
Sbjct: 247 QILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNA-----FEHGGEFTYKQIPISDH 301

Query: 117 PTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQ 176
            + +LS FF  A +FID A S     +LVHC+ G SRS T+ +AYLM   +++L DA   
Sbjct: 302 WSQNLSQFFPEAISFIDEARSKKCG-VLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDF 360

Query: 177 VAKNRC-VLPNRGFLKQLRELDKQL 200
           V + +  + PN  F+ QL + ++ L
Sbjct: 361 VKRKKSNISPNFNFMGQLLDFERTL 385


>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
          Length = 384

 Score = 61.6 bits (148), Expect = 5e-10
 Identities = 45/146 (30%), Positives = 67/146 (45%), Gaps = 9/146 (6%)

Query: 57  EVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDL 116
           E+ P LY+G    A     L     T +LN +                 + Y  +  +D 
Sbjct: 181 EILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACA-------THLHYKWIPVEDS 233

Query: 117 PTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQ 176
            T D+S  F  A  FID  + +   K+LVHC  G SRS T+ +AYLM  K   L +A   
Sbjct: 234 HTADISSHFQEAIDFID-CVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDY 292

Query: 177 VAKNR-CVLPNRGFLKQLRELDKQLV 201
           + + R  V PN GF+ QL + + +++
Sbjct: 293 IKQRRSMVSPNFGFMGQLLQYESEIL 318


>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
          Length = 381

 Score = 61.2 bits (147), Expect = 7e-10
 Identities = 46/147 (31%), Positives = 75/147 (51%), Gaps = 11/147 (7%)

Query: 57  EVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNV--DTGPDYYRDMDIQYHGVEAD 114
           E+ P LY+G    + +   L++ G  ++LN      N+  + G   Y+ + I  H  +  
Sbjct: 209 EILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQ-- 266

Query: 115 DLPTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAI 174
                +LS FF  A +FID A   +   +LVHC+ G SRS T+ +AYLM   ++++ DA 
Sbjct: 267 -----NLSQFFPEAISFIDEARGKNCG-VLVHCLAGISRSVTVTVAYLMQKLNLSMNDAY 320

Query: 175 QQV-AKNRCVLPNRGFLKQLRELDKQL 200
             V  K   + PN  F+ QL + ++ L
Sbjct: 321 DIVKMKKSNISPNFNFMGQLLDFERTL 347


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,540,827
Number of Sequences: 37866
Number of extensions: 373255
Number of successful extensions: 1398
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 1288
Number of HSP's gapped (non-prelim): 81
length of query: 220
length of database: 18,247,518
effective HSP length: 98
effective length of query: 122
effective length of database: 14,536,650
effective search space: 1773471300
effective search space used: 1773471300
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.