Guide to the Human Genome
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Search of human proteins with 4885079

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4885079 ATP synthase, H+ transporting, mitochondrial F1
complex, gamma subunit isoform H (heart) precursor [Homo sapiens]
         (297 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|50345988 ATP synthase, H+ transporting, mitochondrial F1 comp...   570   e-163
gi|4885079 ATP synthase, H+ transporting, mitochondrial F1 compl...   570   e-163
gi|36949366 mutS homolog 4 [Homo sapiens]                              31   1.1  
gi|6912680 meiotic recombination protein SPO11 isoform a [Homo s...    31   1.5  
gi|239753064 PREDICTED: hypothetical protein [Homo sapiens]            30   2.6  
gi|239747619 PREDICTED: hypothetical protein XP_002347911 [Homo ...    30   2.6  
gi|239741490 PREDICTED: hypothetical protein XP_002342214 [Homo ...    30   2.6  
gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens]           30   2.6  
gi|49640009 tetratricopeptide repeat domain 3 [Homo sapiens]           30   2.6  
gi|150010540 FERM domain containing 4B [Homo sapiens]                  30   2.6  
gi|4504063 golgin 97 [Homo sapiens]                                    29   4.4  
gi|207029299 NIMA-related kinase 10 isoform 3 [Homo sapiens]           29   5.7  
gi|21237725 phosphoinositide-3-kinase, catalytic, gamma polypept...    28   7.4  
gi|41281753 NIMA-related kinase 11 isoform 2 [Homo sapiens]            28   9.7  
gi|225637562 NIMA-related kinase 11 isoform 3 [Homo sapiens]           28   9.7  
gi|225637560 NIMA-related kinase 11 isoform 1 [Homo sapiens]           28   9.7  
gi|40255119 RAS and EF-hand domain containing [Homo sapiens]           28   9.7  

>gi|50345988 ATP synthase, H+ transporting, mitochondrial F1
           complex, gamma subunit isoform L (liver) precursor [Homo
           sapiens]
          Length = 298

 Score =  570 bits (1470), Expect = e-163
 Identities = 297/297 (100%), Positives = 297/297 (100%)

Query: 1   MFSRAGVAGLSAWTLQPQWIQVRNMATLKDITRRLKSIKNIQKITKSMKMVAAAKYARAE 60
           MFSRAGVAGLSAWTLQPQWIQVRNMATLKDITRRLKSIKNIQKITKSMKMVAAAKYARAE
Sbjct: 1   MFSRAGVAGLSAWTLQPQWIQVRNMATLKDITRRLKSIKNIQKITKSMKMVAAAKYARAE 60

Query: 61  RELKPARIYGLGSLALYEKADIKGPEDKKKHLLIGVSSDRGLCGAIHSSIAKQMKSEVAT 120
           RELKPARIYGLGSLALYEKADIKGPEDKKKHLLIGVSSDRGLCGAIHSSIAKQMKSEVAT
Sbjct: 61  RELKPARIYGLGSLALYEKADIKGPEDKKKHLLIGVSSDRGLCGAIHSSIAKQMKSEVAT 120

Query: 121 LTAAGKEVMLVGIGDKIRGILYRTHSDQFLVAFKEVGRKPPTFGDASVIALELLNSGYEF 180
           LTAAGKEVMLVGIGDKIRGILYRTHSDQFLVAFKEVGRKPPTFGDASVIALELLNSGYEF
Sbjct: 121 LTAAGKEVMLVGIGDKIRGILYRTHSDQFLVAFKEVGRKPPTFGDASVIALELLNSGYEF 180

Query: 181 DEGSIIFNKFRSVISYKTEEKPIFSLNTVASADSMSIYDDIDADVLQNYQEYNLANIIYY 240
           DEGSIIFNKFRSVISYKTEEKPIFSLNTVASADSMSIYDDIDADVLQNYQEYNLANIIYY
Sbjct: 181 DEGSIIFNKFRSVISYKTEEKPIFSLNTVASADSMSIYDDIDADVLQNYQEYNLANIIYY 240

Query: 241 SLKESTTSEQSARMTAMDNASKNASEMIDKLTLTFNRTRQAVITKELIEIISGAAAL 297
           SLKESTTSEQSARMTAMDNASKNASEMIDKLTLTFNRTRQAVITKELIEIISGAAAL
Sbjct: 241 SLKESTTSEQSARMTAMDNASKNASEMIDKLTLTFNRTRQAVITKELIEIISGAAAL 297


>gi|4885079 ATP synthase, H+ transporting, mitochondrial F1 complex,
           gamma subunit isoform H (heart) precursor [Homo sapiens]
          Length = 297

 Score =  570 bits (1470), Expect = e-163
 Identities = 297/297 (100%), Positives = 297/297 (100%)

Query: 1   MFSRAGVAGLSAWTLQPQWIQVRNMATLKDITRRLKSIKNIQKITKSMKMVAAAKYARAE 60
           MFSRAGVAGLSAWTLQPQWIQVRNMATLKDITRRLKSIKNIQKITKSMKMVAAAKYARAE
Sbjct: 1   MFSRAGVAGLSAWTLQPQWIQVRNMATLKDITRRLKSIKNIQKITKSMKMVAAAKYARAE 60

Query: 61  RELKPARIYGLGSLALYEKADIKGPEDKKKHLLIGVSSDRGLCGAIHSSIAKQMKSEVAT 120
           RELKPARIYGLGSLALYEKADIKGPEDKKKHLLIGVSSDRGLCGAIHSSIAKQMKSEVAT
Sbjct: 61  RELKPARIYGLGSLALYEKADIKGPEDKKKHLLIGVSSDRGLCGAIHSSIAKQMKSEVAT 120

Query: 121 LTAAGKEVMLVGIGDKIRGILYRTHSDQFLVAFKEVGRKPPTFGDASVIALELLNSGYEF 180
           LTAAGKEVMLVGIGDKIRGILYRTHSDQFLVAFKEVGRKPPTFGDASVIALELLNSGYEF
Sbjct: 121 LTAAGKEVMLVGIGDKIRGILYRTHSDQFLVAFKEVGRKPPTFGDASVIALELLNSGYEF 180

Query: 181 DEGSIIFNKFRSVISYKTEEKPIFSLNTVASADSMSIYDDIDADVLQNYQEYNLANIIYY 240
           DEGSIIFNKFRSVISYKTEEKPIFSLNTVASADSMSIYDDIDADVLQNYQEYNLANIIYY
Sbjct: 181 DEGSIIFNKFRSVISYKTEEKPIFSLNTVASADSMSIYDDIDADVLQNYQEYNLANIIYY 240

Query: 241 SLKESTTSEQSARMTAMDNASKNASEMIDKLTLTFNRTRQAVITKELIEIISGAAAL 297
           SLKESTTSEQSARMTAMDNASKNASEMIDKLTLTFNRTRQAVITKELIEIISGAAAL
Sbjct: 241 SLKESTTSEQSARMTAMDNASKNASEMIDKLTLTFNRTRQAVITKELIEIISGAAAL 297


>gi|36949366 mutS homolog 4 [Homo sapiens]
          Length = 936

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 37/181 (20%), Positives = 75/181 (41%), Gaps = 13/181 (7%)

Query: 106 IHSSIAKQMKSEVATLTAAGKEVMLVGIGDKIRGILYRTHSDQFLVAFKEVGRKPPTFGD 165
           I + I   + +E ++   A +    +   D I      T+S  F+   KE+        D
Sbjct: 698 IMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIE-----TNSSTFMKEMKEIAYILHNAND 752

Query: 166 ASVIALELLNSGYEFDEG-SIIFNKFRSVISYKTEEKPIFSLNTVASADSMSIYDDI--- 221
            S+I ++ L  G   +EG  I +     ++S K     +F+ + +      ++Y ++   
Sbjct: 753 KSLILIDELGRGTNTEEGIGICYAVCEYLLSLKA--FTLFATHFLELCHIDALYPNVENM 810

Query: 222 --DADVLQNYQEYNLANIIYYSLKESTTSEQSARMTAMDNASKNASEMIDKLTLTFNRTR 279
             +   ++N      A +  Y L +  T E++  + A + +S   S ++D   +T   TR
Sbjct: 811 HFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGLKAAEVSSLPPSIVLDAKEITTQITR 870

Query: 280 Q 280
           Q
Sbjct: 871 Q 871


>gi|6912680 meiotic recombination protein SPO11 isoform a [Homo
           sapiens]
          Length = 396

 Score = 30.8 bits (68), Expect = 1.5
 Identities = 21/85 (24%), Positives = 39/85 (45%), Gaps = 10/85 (11%)

Query: 145 HSDQFLVAFKEVGRKPPTFGDASVIALELLNSGYEFDEGSIIFNKFRSVI-SYKTEEKPI 203
           H +  L A +  GR+PPT G     + E+L S         I N  + +I S    E P 
Sbjct: 19  HRESLLAALRRGGREPPTGGSRLASSSEVLAS---------IENIIQDIITSLARNEAPA 69

Query: 204 FSLNTVASADSMSIYDDIDADVLQN 228
           F+++  +S +++   D +   ++ +
Sbjct: 70  FTIDNRSSWENIKFEDSVGLQMVSH 94


>gi|239753064 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 201

 Score = 30.0 bits (66), Expect = 2.6
 Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 2/56 (3%)

Query: 91  HLLIGVSSDRGLCGAIHSSIAKQMKSEVATLTAAGKEVMLVGIGDKIRGILYRTHS 146
           HLL GV    GL G +H    + +K ++  L A G  +   G+G++  G+L  +H+
Sbjct: 61  HLLEGVEGQHGLDGHVHGGHVEGLKHDLGHLLAVGLGIE-GGLGEQ-GGVLLGSHA 114


>gi|239747619 PREDICTED: hypothetical protein XP_002347911 [Homo
           sapiens]
          Length = 201

 Score = 30.0 bits (66), Expect = 2.6
 Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 2/56 (3%)

Query: 91  HLLIGVSSDRGLCGAIHSSIAKQMKSEVATLTAAGKEVMLVGIGDKIRGILYRTHS 146
           HLL GV    GL G +H    + +K ++  L A G  +   G+G++  G+L  +H+
Sbjct: 61  HLLEGVEGQHGLDGHVHGGHVEGLKHDLGHLLAVGLGIE-GGLGEQ-GGVLLGSHA 114


>gi|239741490 PREDICTED: hypothetical protein XP_002342214 [Homo
           sapiens]
          Length = 201

 Score = 30.0 bits (66), Expect = 2.6
 Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 2/56 (3%)

Query: 91  HLLIGVSSDRGLCGAIHSSIAKQMKSEVATLTAAGKEVMLVGIGDKIRGILYRTHS 146
           HLL GV    GL G +H    + +K ++  L A G  +   G+G++  G+L  +H+
Sbjct: 61  HLLEGVEGQHGLDGHVHGGHVEGLKHDLGHLLAVGLGIE-GGLGEQ-GGVLLGSHA 114


>gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens]
          Length = 2025

 Score = 30.0 bits (66), Expect = 2.6
 Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 1/51 (1%)

Query: 17   PQWIQVRNMATLKDITRRLKSIKNIQKI-TKSMKMVAAAKYARAERELKPA 66
            P+++ + N   LK +  RLK  +  + I TK  ++  A +Y R + +L PA
Sbjct: 1160 PRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEYVRVKLQLNPA 1210


>gi|49640009 tetratricopeptide repeat domain 3 [Homo sapiens]
          Length = 2025

 Score = 30.0 bits (66), Expect = 2.6
 Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 1/51 (1%)

Query: 17   PQWIQVRNMATLKDITRRLKSIKNIQKI-TKSMKMVAAAKYARAERELKPA 66
            P+++ + N   LK +  RLK  +  + I TK  ++  A +Y R + +L PA
Sbjct: 1160 PRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEYVRVKLQLNPA 1210


>gi|150010540 FERM domain containing 4B [Homo sapiens]
          Length = 1034

 Score = 30.0 bits (66), Expect = 2.6
 Identities = 21/82 (25%), Positives = 35/82 (42%), Gaps = 3/82 (3%)

Query: 193 VISYKTEEKPIFSLNTVASADSMSIYDDIDADVLQNYQEYNLANII---YYSLKESTTSE 249
           ++S    +KP FSL+    + S  I DD  +   Q+  EY     +   YY+ +   T  
Sbjct: 701 LLSEMDSDKPFFSLSKSQRSSSTEILDDGSSYTSQSSTEYYCVTPVTGPYYTTQTLDTRT 760

Query: 250 QSARMTAMDNASKNASEMIDKL 271
           +  R +   N S + S  +  L
Sbjct: 761 RGRRRSKKQNVSTSNSGSMPNL 782


>gi|4504063 golgin 97 [Homo sapiens]
          Length = 767

 Score = 29.3 bits (64), Expect = 4.4
 Identities = 27/118 (22%), Positives = 50/118 (42%), Gaps = 20/118 (16%)

Query: 166 ASVIALELLNSGYEFDEGSIIFNKFRSVISYKTEEKPIFSLNTVASADSMSIYDDIDADV 225
           A  +AL L     E+ E      K +++++ + +E    S+N     D M        D 
Sbjct: 121 AEGLALALARKDQEWSEKMDQLEKEKNILTAQLQEMKNQSMNLFQRRDEM--------DE 172

Query: 226 LQNYQEYNLANIIYYSLK------------ESTTSEQSARMTAMDNASKNASEMIDKL 271
           L+ +Q+  L+ I +  LK            E+ T E S     + N+++ +S++  KL
Sbjct: 173 LEGFQQQELSKIKHMLLKKEESLGKMEQELEARTRELSRTQEELMNSNQMSSDLSQKL 230


>gi|207029299 NIMA-related kinase 10 isoform 3 [Homo sapiens]
          Length = 712

 Score = 28.9 bits (63), Expect = 5.7
 Identities = 19/48 (39%), Positives = 23/48 (47%), Gaps = 2/48 (4%)

Query: 119 ATLTAAGKEVMLVGIGDKIRGILY--RTHSDQFLVAFKEVGRKPPTFG 164
           A L   G   +L  +G    G +Y  R HS Q L+A KEV    P FG
Sbjct: 511 APLKYIGNYAILDHLGSGAFGCVYKVRKHSGQNLLAMKEVNLHNPAFG 558


>gi|21237725 phosphoinositide-3-kinase, catalytic, gamma polypeptide
           [Homo sapiens]
          Length = 1102

 Score = 28.5 bits (62), Expect = 7.4
 Identities = 12/31 (38%), Positives = 22/31 (70%)

Query: 26  ATLKDITRRLKSIKNIQKITKSMKMVAAAKY 56
           A L D T++++ I+ +QK+T  +K ++A KY
Sbjct: 727 AMLHDFTQQVQVIEMLQKVTLDIKSLSAEKY 757


>gi|41281753 NIMA-related kinase 11 isoform 2 [Homo sapiens]
          Length = 470

 Score = 28.1 bits (61), Expect = 9.7
 Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 3/60 (5%)

Query: 34  RLKSIKNIQKITKSMKMVAAAKY---ARAERELKPARIYGLGSLALYEKADIKGPEDKKK 90
           RL+ ++   +  + +K +   KY   ++  +EL+      L    L+EK  +KG E+K++
Sbjct: 346 RLRKLQAADEKARKLKKIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEEKEE 405


>gi|225637562 NIMA-related kinase 11 isoform 3 [Homo sapiens]
          Length = 599

 Score = 28.1 bits (61), Expect = 9.7
 Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 3/60 (5%)

Query: 34  RLKSIKNIQKITKSMKMVAAAKY---ARAERELKPARIYGLGSLALYEKADIKGPEDKKK 90
           RL+ ++   +  + +K +   KY   ++  +EL+      L    L+EK  +KG E+K++
Sbjct: 346 RLRKLQAADEKARKLKKIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEEKEE 405


>gi|225637560 NIMA-related kinase 11 isoform 1 [Homo sapiens]
          Length = 645

 Score = 28.1 bits (61), Expect = 9.7
 Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 3/60 (5%)

Query: 34  RLKSIKNIQKITKSMKMVAAAKY---ARAERELKPARIYGLGSLALYEKADIKGPEDKKK 90
           RL+ ++   +  + +K +   KY   ++  +EL+      L    L+EK  +KG E+K++
Sbjct: 346 RLRKLQAADEKARKLKKIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEEKEE 405


>gi|40255119 RAS and EF-hand domain containing [Homo sapiens]
          Length = 740

 Score = 28.1 bits (61), Expect = 9.7
 Identities = 23/97 (23%), Positives = 43/97 (44%), Gaps = 5/97 (5%)

Query: 20  IQVRNMATLKDITRRLKSIKNIQKITKSMKMVAAAKYARAERELKPARIYGLGSLALYEK 79
           + + N    KD+     +I  +Q    ++K   A +    ER+L+  R Y     +L  +
Sbjct: 279 LSMENQKVKKDLLEAQTNIAFLQSELDALKSDYADQSLNTERDLEIIRAYTEDRNSLERQ 338

Query: 80  ADIKGPEDKKKHLLIGVSSDRGLCGAIHSSIAKQMKS 116
            +I    ++K H      S+ GL  A+ +S +K  +S
Sbjct: 339 IEILQTANRKLH-----DSNDGLRSALENSYSKFNRS 370


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.130    0.353 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,788,455
Number of Sequences: 37866
Number of extensions: 315675
Number of successful extensions: 869
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 862
Number of HSP's gapped (non-prelim): 17
length of query: 297
length of database: 18,247,518
effective HSP length: 102
effective length of query: 195
effective length of database: 14,385,186
effective search space: 2805111270
effective search space used: 2805111270
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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