Guide to the Human Genome
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Search of human proteins with 48762685

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo
sapiens]
         (919 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap...  1793   0.0  
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap...  1793   0.0  
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap...  1776   0.0  
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap...  1716   0.0  
gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ...  1179   0.0  
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom...   484   e-136
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...   484   e-136
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom...   484   e-136
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...   484   e-136
gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom...   484   e-136
gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom...   484   e-136
gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom...   484   e-136
gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [...   478   e-135
gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H...   478   e-134
gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [...   459   e-129
gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [...   459   e-129
gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ...   442   e-124
gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]             376   e-104
gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]   375   e-104
gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi...   372   e-102
gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi...   372   e-102
gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]   372   e-102
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi...   363   e-100
gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]    356   6e-98
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]   326   5e-89
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa...   300   3e-81
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa...   300   3e-81
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap...   293   4e-79
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa...   290   3e-78
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa...   290   3e-78

>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo
           sapiens]
          Length = 949

 Score = 1793 bits (4644), Expect = 0.0
 Identities = 919/919 (100%), Positives = 919/919 (100%)

Query: 1   MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGW 60
           MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGW
Sbjct: 1   MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGW 60

Query: 61  NEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQ 120
           NEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQ
Sbjct: 61  NEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQ 120

Query: 121 EYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVD 180
           EYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVD
Sbjct: 121 EYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVD 180

Query: 181 LSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSE 240
           LSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSE
Sbjct: 181 LSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSE 240

Query: 241 FGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVS 300
           FGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVS
Sbjct: 241 FGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVS 300

Query: 301 LAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEM 360
           LAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEM
Sbjct: 301 LAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEM 360

Query: 361 TVTHIFTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNT 420
           TVTHIFTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNT
Sbjct: 361 TVTHIFTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNT 420

Query: 421 LMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMK 480
           LMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMK
Sbjct: 421 LMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMK 480

Query: 481 GAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGPELGQLTFLG 540
           GAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGPELGQLTFLG
Sbjct: 481 GAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGPELGQLTFLG 540

Query: 541 LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEID 600
           LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEID
Sbjct: 541 LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEID 600

Query: 601 AMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVA 660
           AMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVA
Sbjct: 601 AMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVA 660

Query: 661 MGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLA 720
           MGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLA
Sbjct: 661 MGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLA 720

Query: 721 TLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKIL 780
           TLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKIL
Sbjct: 721 TLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKIL 780

Query: 781 VSSIIIVCGTLFVFWRELRDNVITPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCS 840
           VSSIIIVCGTLFVFWRELRDNVITPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCS
Sbjct: 781 VSSIIIVCGTLFVFWRELRDNVITPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCS 840

Query: 841 NRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEIIKKVER 900
           NRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEIIKKVER
Sbjct: 841 NRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEIIKKVER 900

Query: 901 SREKIQKHVSSTSSSFLEV 919
           SREKIQKHVSSTSSSFLEV
Sbjct: 901 SREKIQKHVSSTSSSFLEV 919


>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo
           sapiens]
          Length = 919

 Score = 1793 bits (4644), Expect = 0.0
 Identities = 919/919 (100%), Positives = 919/919 (100%)

Query: 1   MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGW 60
           MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGW
Sbjct: 1   MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGW 60

Query: 61  NEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQ 120
           NEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQ
Sbjct: 61  NEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQ 120

Query: 121 EYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVD 180
           EYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVD
Sbjct: 121 EYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVD 180

Query: 181 LSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSE 240
           LSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSE
Sbjct: 181 LSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSE 240

Query: 241 FGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVS 300
           FGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVS
Sbjct: 241 FGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVS 300

Query: 301 LAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEM 360
           LAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEM
Sbjct: 301 LAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEM 360

Query: 361 TVTHIFTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNT 420
           TVTHIFTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNT
Sbjct: 361 TVTHIFTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNT 420

Query: 421 LMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMK 480
           LMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMK
Sbjct: 421 LMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMK 480

Query: 481 GAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGPELGQLTFLG 540
           GAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGPELGQLTFLG
Sbjct: 481 GAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGPELGQLTFLG 540

Query: 541 LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEID 600
           LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEID
Sbjct: 541 LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEID 600

Query: 601 AMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVA 660
           AMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVA
Sbjct: 601 AMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVA 660

Query: 661 MGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLA 720
           MGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLA
Sbjct: 661 MGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLA 720

Query: 721 TLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKIL 780
           TLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKIL
Sbjct: 721 TLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKIL 780

Query: 781 VSSIIIVCGTLFVFWRELRDNVITPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCS 840
           VSSIIIVCGTLFVFWRELRDNVITPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCS
Sbjct: 781 VSSIIIVCGTLFVFWRELRDNVITPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCS 840

Query: 841 NRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEIIKKVER 900
           NRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEIIKKVER
Sbjct: 841 NRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEIIKKVER 900

Query: 901 SREKIQKHVSSTSSSFLEV 919
           SREKIQKHVSSTSSSFLEV
Sbjct: 901 SREKIQKHVSSTSSSFLEV 919


>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo
           sapiens]
          Length = 939

 Score = 1776 bits (4600), Expect = 0.0
 Identities = 909/909 (100%), Positives = 909/909 (100%)

Query: 1   MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGW 60
           MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGW
Sbjct: 1   MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGW 60

Query: 61  NEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQ 120
           NEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQ
Sbjct: 61  NEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQ 120

Query: 121 EYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVD 180
           EYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVD
Sbjct: 121 EYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVD 180

Query: 181 LSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSE 240
           LSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSE
Sbjct: 181 LSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSE 240

Query: 241 FGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVS 300
           FGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVS
Sbjct: 241 FGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVS 300

Query: 301 LAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEM 360
           LAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEM
Sbjct: 301 LAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEM 360

Query: 361 TVTHIFTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNT 420
           TVTHIFTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNT
Sbjct: 361 TVTHIFTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNT 420

Query: 421 LMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMK 480
           LMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMK
Sbjct: 421 LMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMK 480

Query: 481 GAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGPELGQLTFLG 540
           GAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGPELGQLTFLG
Sbjct: 481 GAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGPELGQLTFLG 540

Query: 541 LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEID 600
           LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEID
Sbjct: 541 LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEID 600

Query: 601 AMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVA 660
           AMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVA
Sbjct: 601 AMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVA 660

Query: 661 MGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLA 720
           MGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLA
Sbjct: 661 MGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLA 720

Query: 721 TLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKIL 780
           TLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKIL
Sbjct: 721 TLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKIL 780

Query: 781 VSSIIIVCGTLFVFWRELRDNVITPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCS 840
           VSSIIIVCGTLFVFWRELRDNVITPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCS
Sbjct: 781 VSSIIIVCGTLFVFWRELRDNVITPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCS 840

Query: 841 NRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEIIKKVER 900
           NRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEIIKKVER
Sbjct: 841 NRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEIIKKVER 900

Query: 901 SREKIQKHV 909
           SREKIQKHV
Sbjct: 901 SREKIQKHV 909


>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo
           sapiens]
          Length = 888

 Score = 1716 bits (4445), Expect = 0.0
 Identities = 877/878 (99%), Positives = 877/878 (99%)

Query: 1   MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGW 60
           MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGW
Sbjct: 1   MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGW 60

Query: 61  NEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQ 120
           NEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQ
Sbjct: 61  NEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQ 120

Query: 121 EYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVD 180
           EYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVD
Sbjct: 121 EYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVD 180

Query: 181 LSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSE 240
           LSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSE
Sbjct: 181 LSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSE 240

Query: 241 FGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVS 300
           FGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVS
Sbjct: 241 FGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVS 300

Query: 301 LAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEM 360
           LAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEM
Sbjct: 301 LAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEM 360

Query: 361 TVTHIFTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNT 420
           TVTHIFTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNT
Sbjct: 361 TVTHIFTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNT 420

Query: 421 LMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMK 480
           LMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMK
Sbjct: 421 LMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMK 480

Query: 481 GAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGPELGQLTFLG 540
           GAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGPELGQLTFLG
Sbjct: 481 GAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGPELGQLTFLG 540

Query: 541 LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEID 600
           LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEID
Sbjct: 541 LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEID 600

Query: 601 AMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVA 660
           AMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVA
Sbjct: 601 AMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVA 660

Query: 661 MGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLA 720
           MGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLA
Sbjct: 661 MGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLA 720

Query: 721 TLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKIL 780
           TLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKIL
Sbjct: 721 TLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKIL 780

Query: 781 VSSIIIVCGTLFVFWRELRDNVITPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCS 840
           VSSIIIVCGTLFVFWRELRDNVITPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCS
Sbjct: 781 VSSIIIVCGTLFVFWRELRDNVITPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCS 840

Query: 841 NRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDL 878
           NRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSIL L
Sbjct: 841 NRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILGL 878


>gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo
           sapiens]
          Length = 946

 Score = 1179 bits (3051), Expect = 0.0
 Identities = 599/902 (66%), Positives = 728/902 (80%), Gaps = 9/902 (0%)

Query: 13  ENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLW 72
           E E  +  L  K+A +    ++A     DL  GL++  V+ RR  HGWNEF     EP+W
Sbjct: 44  EKEKKVTALPPKEACKCQKEDLARAFCVDLHTGLSEFSVTQRRLAHGWNEFVADNSEPVW 103

Query: 73  KKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELS 132
           KKY+ QFKNPLI+LLL SA++SVL  +++DAVSI  A+L+VVTVAF+QEYRSEKSLEEL+
Sbjct: 104 KKYLDQFKNPLILLLLGSALVSVLTKEYEDAVSIATAVLVVVTVAFIQEYRSEKSLEELT 163

Query: 133 KLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGET 192
           K+VPPEC+C+REGKL+H LAR+LVPGD V LS+GDR+PAD+RL E  DL +DESS TGE 
Sbjct: 164 KMVPPECNCLREGKLQHLLARELVPGDVVSLSIGDRIPADIRLTEVTDLLVDESSFTGEA 223

Query: 193 TPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEE 252
            PCSK  +P      GDL + SNI FMGTLV+ G+ +GVVIGTGE+S+FGEVFKMMQAEE
Sbjct: 224 EPCSKTDSPLTGG--GDLTTLSNIVFMGTLVQYGRGQGVVIGTGESSQFGEVFKMMQAEE 281

Query: 253 APKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPI 312
            PKTPLQKSMD LGKQL+ +SFGIIG+IML+GW  GK +L MFTI VSLAVAAIPEGLPI
Sbjct: 282 TPKTPLQKSMDRLGKQLTLFSFGIIGLIMLIGWSQGKQLLSMFTIGVSLAVAAIPEGLPI 341

Query: 313 VVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLH 372
           VV VTL LGV+RM KKR IVKKLPIVETLGCC+V+CSDKTGTLT NEMTVT + TSDGL 
Sbjct: 342 VVMVTLVLGVLRMAKKRVIVKKLPIVETLGCCSVLCSDKTGTLTANEMTVTQLVTSDGLR 401

Query: 373 AEVTGVGYNQFGEVIV--DGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGAL 430
           AEV+GVGY+  G V +    +V+  F N +V ++VEAGCV N+AVIR N +MG+PTEGAL
Sbjct: 402 AEVSGVGYDGQGTVCLLPSKEVIKEFSNVSVGKLVEAGCVANNAVIRKNAVMGQPTEGAL 461

Query: 431 IALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYC 490
           +ALAMKM L  ++  YIRK E PFSSEQKWMAVKC  +T+ D+ +I FMKGA E+VI+YC
Sbjct: 462 MALAMKMDLSDIKNSYIRKKEIPFSSEQKWMAVKCSLKTE-DQEDIYFMKGALEEVIRYC 520

Query: 491 TTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGPELGQLTFLGLVGIIDPPRT 550
           T Y + G  L LT QQR    QE+ RMGS GLRVLALASGPELG+LTFLGLVGIIDPPR 
Sbjct: 521 TMYNNGGIPLPLTPQQRSFCLQEEKRMGSLGLRVLALASGPELGRLTFLGLVGIIDPPRV 580

Query: 551 GVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEIDAMDVQQLSQI 610
           GVKEAV  L  SGVS+KMITGD+ ETA+AI   +GL +   Q++SGEE+D+++  +L+  
Sbjct: 581 GVKEAVQVLSESGVSVKMITGDALETALAIGRNIGLCNGKLQAMSGEEVDSVEKGELADR 640

Query: 611 VPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCK 670
           V KV+VF+R SP+HK+KIIK+LQ++G++VAMTGDGVNDAVALK+ADIG+AMGQTGTDV K
Sbjct: 641 VGKVSVFFRTSPKHKLKIIKALQESGAIVAMTGDGVNDAVALKSADIGIAMGQTGTDVSK 700

Query: 671 EAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLN 730
           EAA+MILVDDDF  IM+A+EEGKGI+ NIKNFVRFQLSTSI+AL+LI+L+T+ N P+PLN
Sbjct: 701 EAANMILVDDDFSAIMNAVEEGKGIFYNIKNFVRFQLSTSISALSLITLSTVFNLPSPLN 760

Query: 731 AMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCGT 790
           AMQILWINIIMDGPPAQSLGVEPVDKD  R+PPR+ +D+IL++ LILKIL+S+ II+ GT
Sbjct: 761 AMQILWINIIMDGPPAQSLGVEPVDKDAFRQPPRSVRDTILSRALILKILMSAAIIISGT 820

Query: 791 LFVFWREL-RDNVITPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVL 849
           LF+FW+E+  D   TPR TTMTFTCFVFFD+FNAL+ RSQTK +FEIG   N MF Y+VL
Sbjct: 821 LFIFWKEMPEDRASTPRTTTMTFTCFVFFDLFNALTCRSQTKLIFEIGFLRNHMFLYSVL 880

Query: 850 GSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEIIKKVER---SREKIQ 906
           GSI+GQL VIY PPLQ+VFQTE+L  LDLLFL GL SSV I++E++K  E+   S +++Q
Sbjct: 881 GSILGQLAVIYIPPLQRVFQTENLGALDLLFLTGLASSVFILSELLKLCEKYCCSPKRVQ 940

Query: 907 KH 908
            H
Sbjct: 941 MH 942


>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
           sapiens]
          Length = 999

 Score =  484 bits (1246), Expect = e-136
 Identities = 338/993 (34%), Positives = 516/993 (51%), Gaps = 129/993 (12%)

Query: 29  LPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLL 88
           LP ++V        + GL+  +V+  R  +G NE    E + LW+  + QF++ L+ +LL
Sbjct: 7   LPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILL 66

Query: 89  ASAVISVLMHQFDDAVSITVA-------ILIVVTVAFV---QEYRSEKSLEELSKLVPPE 138
            +A++S ++  F++    T A       +LI+V  A V   QE  +E ++E L +  P  
Sbjct: 67  LAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEM 126

Query: 139 CHCVREGK--LEHTLARDLVPGDTVCLSVGDRVPADLRLFE--AVDLSIDESSLTGETTP 194
              +R  +  ++   ARD+VPGD V ++VGD+VPADLRL E  +  L +D+S LTGE+  
Sbjct: 127 GKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVS 186

Query: 195 CSKVTA--PQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEE 252
            +K T   P P A N D   + N+ F GT +  GKA GV + TG ++E G++   M A E
Sbjct: 187 VTKHTEAIPDPRAVNQD---KKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVE 243

Query: 253 APKTPLQKSMDLLGKQLSFYSFGIIGIIMLV-------------GWLLGKDILEMFTISV 299
             +TPLQ+ +D  G+QLS ++  +I + + V              WL G   +  F I+V
Sbjct: 244 PERTPLQRKLDEFGRQLS-HAISVICVAVWVINIGHFADPAHGGSWLRGA--VYYFKIAV 300

Query: 300 SLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNE 359
           +LAVAAIPEGLP V+T  LALG  RM +K AIV+ LP VETLGC +VICSDKTGTLT N+
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 360 MTVTHIFT-------SDGLHA-EVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVC 411
           M+V  +F        S  LH   ++G  Y   GEV      V       +  +     +C
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420

Query: 412 NDAVIRNNTL------MGKPTEGALIALAMKMGLDGLQQDYIRKAE-------------- 451
           ND+ +  N        +G+ TE AL  L  KM +       + + E              
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480

Query: 452 ----YPFSSEQKWMAVKCV----HRTQQDRPEICFMKGAYEQVIKYCTTYQSKGQTLTLT 503
                 FS ++K M+V C     H T Q      F+KGA E VI+ C++ +   +T  LT
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSK--MFVKGAPESVIERCSSVRVGSRTAPLT 538

Query: 504 QQQRDVYQQEKARMGSAG--LRVLALASGP--------ELGQ----------LTFLGLVG 543
              R+    +    GS    LR LALA+          EL            LTF+G VG
Sbjct: 539 PTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVG 598

Query: 544 IIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTS----QSVSGEEI 599
           ++DPPR  V   +T    +G+ + MITGD++ TAVAI  RLG++  T     ++ +G E 
Sbjct: 599 MLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREF 658

Query: 600 DAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGV 659
           D +  +Q  Q       F R  P HK +I+++LQ    + AMTGDGVNDA ALK A+IG+
Sbjct: 659 DDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGI 718

Query: 660 AMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISL 719
           AMG +GT V K AA+M+L DD+F +I++A+EEG+ IY+N+K F+R+ +S+++  +  I L
Sbjct: 719 AMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFL 777

Query: 720 ATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKI 779
             ++  P  L  +Q+LW+N++ DG PA +LG  P D D++ K PR+ ++++++  L  + 
Sbjct: 778 TAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRY 837

Query: 780 LVSSIIIVCGTL------FVF--------WRELRDNVITPRD-----------------T 808
           L   + +   T+      FV+        + +LR+ +    D                 T
Sbjct: 838 LAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPT 897

Query: 809 TMTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVF 868
           TM  +  V  +M NAL+S S+ +S+  +    N     AV  S+    L++  PPL  +F
Sbjct: 898 TMALSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIF 957

Query: 869 QTESLSILDLLFLLGLTSSVCIVAEIIKKVERS 901
           Q   LS    + +L ++  V ++ E +K + R+
Sbjct: 958 QVTPLSGRQWVVVLQISLPVILLDEALKYLSRN 990


>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
           sapiens]
          Length = 1029

 Score =  484 bits (1246), Expect = e-136
 Identities = 338/993 (34%), Positives = 516/993 (51%), Gaps = 129/993 (12%)

Query: 29  LPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLL 88
           LP ++V        + GL+  +V+  R  +G NE    E + LW+  + QF++ L+ +LL
Sbjct: 7   LPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILL 66

Query: 89  ASAVISVLMHQFDDAVSITVA-------ILIVVTVAFV---QEYRSEKSLEELSKLVPPE 138
            +A++S ++  F++    T A       +LI+V  A V   QE  +E ++E L +  P  
Sbjct: 67  LAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEM 126

Query: 139 CHCVREGK--LEHTLARDLVPGDTVCLSVGDRVPADLRLFE--AVDLSIDESSLTGETTP 194
              +R  +  ++   ARD+VPGD V ++VGD+VPADLRL E  +  L +D+S LTGE+  
Sbjct: 127 GKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVS 186

Query: 195 CSKVTA--PQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEE 252
            +K T   P P A N D   + N+ F GT +  GKA GV + TG ++E G++   M A E
Sbjct: 187 VTKHTEAIPDPRAVNQD---KKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVE 243

Query: 253 APKTPLQKSMDLLGKQLSFYSFGIIGIIMLV-------------GWLLGKDILEMFTISV 299
             +TPLQ+ +D  G+QLS ++  +I + + V              WL G   +  F I+V
Sbjct: 244 PERTPLQRKLDEFGRQLS-HAISVICVAVWVINIGHFADPAHGGSWLRGA--VYYFKIAV 300

Query: 300 SLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNE 359
           +LAVAAIPEGLP V+T  LALG  RM +K AIV+ LP VETLGC +VICSDKTGTLT N+
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 360 MTVTHIFT-------SDGLHA-EVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVC 411
           M+V  +F        S  LH   ++G  Y   GEV      V       +  +     +C
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420

Query: 412 NDAVIRNNTL------MGKPTEGALIALAMKMGLDGLQQDYIRKAE-------------- 451
           ND+ +  N        +G+ TE AL  L  KM +       + + E              
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480

Query: 452 ----YPFSSEQKWMAVKCV----HRTQQDRPEICFMKGAYEQVIKYCTTYQSKGQTLTLT 503
                 FS ++K M+V C     H T Q      F+KGA E VI+ C++ +   +T  LT
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSK--MFVKGAPESVIERCSSVRVGSRTAPLT 538

Query: 504 QQQRDVYQQEKARMGSAG--LRVLALASGP--------ELGQ----------LTFLGLVG 543
              R+    +    GS    LR LALA+          EL            LTF+G VG
Sbjct: 539 PTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVG 598

Query: 544 IIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTS----QSVSGEEI 599
           ++DPPR  V   +T    +G+ + MITGD++ TAVAI  RLG++  T     ++ +G E 
Sbjct: 599 MLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREF 658

Query: 600 DAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGV 659
           D +  +Q  Q       F R  P HK +I+++LQ    + AMTGDGVNDA ALK A+IG+
Sbjct: 659 DDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGI 718

Query: 660 AMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISL 719
           AMG +GT V K AA+M+L DD+F +I++A+EEG+ IY+N+K F+R+ +S+++  +  I L
Sbjct: 719 AMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFL 777

Query: 720 ATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKI 779
             ++  P  L  +Q+LW+N++ DG PA +LG  P D D++ K PR+ ++++++  L  + 
Sbjct: 778 TAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRY 837

Query: 780 LVSSIIIVCGTL------FVF--------WRELRDNVITPRD-----------------T 808
           L   + +   T+      FV+        + +LR+ +    D                 T
Sbjct: 838 LAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPT 897

Query: 809 TMTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVF 868
           TM  +  V  +M NAL+S S+ +S+  +    N     AV  S+    L++  PPL  +F
Sbjct: 898 TMALSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIF 957

Query: 869 QTESLSILDLLFLLGLTSSVCIVAEIIKKVERS 901
           Q   LS    + +L ++  V ++ E +K + R+
Sbjct: 958 QVTPLSGRQWVVVLQISLPVILLDEALKYLSRN 990


>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
           sapiens]
          Length = 998

 Score =  484 bits (1246), Expect = e-136
 Identities = 338/993 (34%), Positives = 516/993 (51%), Gaps = 129/993 (12%)

Query: 29  LPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLL 88
           LP ++V        + GL+  +V+  R  +G NE    E + LW+  + QF++ L+ +LL
Sbjct: 7   LPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILL 66

Query: 89  ASAVISVLMHQFDDAVSITVA-------ILIVVTVAFV---QEYRSEKSLEELSKLVPPE 138
            +A++S ++  F++    T A       +LI+V  A V   QE  +E ++E L +  P  
Sbjct: 67  LAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEM 126

Query: 139 CHCVREGK--LEHTLARDLVPGDTVCLSVGDRVPADLRLFE--AVDLSIDESSLTGETTP 194
              +R  +  ++   ARD+VPGD V ++VGD+VPADLRL E  +  L +D+S LTGE+  
Sbjct: 127 GKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVS 186

Query: 195 CSKVTA--PQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEE 252
            +K T   P P A N D   + N+ F GT +  GKA GV + TG ++E G++   M A E
Sbjct: 187 VTKHTEAIPDPRAVNQD---KKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVE 243

Query: 253 APKTPLQKSMDLLGKQLSFYSFGIIGIIMLV-------------GWLLGKDILEMFTISV 299
             +TPLQ+ +D  G+QLS ++  +I + + V              WL G   +  F I+V
Sbjct: 244 PERTPLQRKLDEFGRQLS-HAISVICVAVWVINIGHFADPAHGGSWLRGA--VYYFKIAV 300

Query: 300 SLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNE 359
           +LAVAAIPEGLP V+T  LALG  RM +K AIV+ LP VETLGC +VICSDKTGTLT N+
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 360 MTVTHIFT-------SDGLHA-EVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVC 411
           M+V  +F        S  LH   ++G  Y   GEV      V       +  +     +C
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420

Query: 412 NDAVIRNNTL------MGKPTEGALIALAMKMGLDGLQQDYIRKAE-------------- 451
           ND+ +  N        +G+ TE AL  L  KM +       + + E              
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480

Query: 452 ----YPFSSEQKWMAVKCV----HRTQQDRPEICFMKGAYEQVIKYCTTYQSKGQTLTLT 503
                 FS ++K M+V C     H T Q      F+KGA E VI+ C++ +   +T  LT
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSK--MFVKGAPESVIERCSSVRVGSRTAPLT 538

Query: 504 QQQRDVYQQEKARMGSAG--LRVLALASGP--------ELGQ----------LTFLGLVG 543
              R+    +    GS    LR LALA+          EL            LTF+G VG
Sbjct: 539 PTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVG 598

Query: 544 IIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTS----QSVSGEEI 599
           ++DPPR  V   +T    +G+ + MITGD++ TAVAI  RLG++  T     ++ +G E 
Sbjct: 599 MLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREF 658

Query: 600 DAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGV 659
           D +  +Q  Q       F R  P HK +I+++LQ    + AMTGDGVNDA ALK A+IG+
Sbjct: 659 DDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGI 718

Query: 660 AMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISL 719
           AMG +GT V K AA+M+L DD+F +I++A+EEG+ IY+N+K F+R+ +S+++  +  I L
Sbjct: 719 AMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFL 777

Query: 720 ATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKI 779
             ++  P  L  +Q+LW+N++ DG PA +LG  P D D++ K PR+ ++++++  L  + 
Sbjct: 778 TAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRY 837

Query: 780 LVSSIIIVCGTL------FVF--------WRELRDNVITPRD-----------------T 808
           L   + +   T+      FV+        + +LR+ +    D                 T
Sbjct: 838 LAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPT 897

Query: 809 TMTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVF 868
           TM  +  V  +M NAL+S S+ +S+  +    N     AV  S+    L++  PPL  +F
Sbjct: 898 TMALSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIF 957

Query: 869 QTESLSILDLLFLLGLTSSVCIVAEIIKKVERS 901
           Q   LS    + +L ++  V ++ E +K + R+
Sbjct: 958 QVTPLSGRQWVVVLQISLPVILLDEALKYLSRN 990


>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
           sapiens]
          Length = 1029

 Score =  484 bits (1246), Expect = e-136
 Identities = 338/993 (34%), Positives = 516/993 (51%), Gaps = 129/993 (12%)

Query: 29  LPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLL 88
           LP ++V        + GL+  +V+  R  +G NE    E + LW+  + QF++ L+ +LL
Sbjct: 7   LPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILL 66

Query: 89  ASAVISVLMHQFDDAVSITVA-------ILIVVTVAFV---QEYRSEKSLEELSKLVPPE 138
            +A++S ++  F++    T A       +LI+V  A V   QE  +E ++E L +  P  
Sbjct: 67  LAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEM 126

Query: 139 CHCVREGK--LEHTLARDLVPGDTVCLSVGDRVPADLRLFE--AVDLSIDESSLTGETTP 194
              +R  +  ++   ARD+VPGD V ++VGD+VPADLRL E  +  L +D+S LTGE+  
Sbjct: 127 GKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVS 186

Query: 195 CSKVTA--PQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEE 252
            +K T   P P A N D   + N+ F GT +  GKA GV + TG ++E G++   M A E
Sbjct: 187 VTKHTEAIPDPRAVNQD---KKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVE 243

Query: 253 APKTPLQKSMDLLGKQLSFYSFGIIGIIMLV-------------GWLLGKDILEMFTISV 299
             +TPLQ+ +D  G+QLS ++  +I + + V              WL G   +  F I+V
Sbjct: 244 PERTPLQRKLDEFGRQLS-HAISVICVAVWVINIGHFADPAHGGSWLRGA--VYYFKIAV 300

Query: 300 SLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNE 359
           +LAVAAIPEGLP V+T  LALG  RM +K AIV+ LP VETLGC +VICSDKTGTLT N+
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 360 MTVTHIFT-------SDGLHA-EVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVC 411
           M+V  +F        S  LH   ++G  Y   GEV      V       +  +     +C
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420

Query: 412 NDAVIRNNTL------MGKPTEGALIALAMKMGLDGLQQDYIRKAE-------------- 451
           ND+ +  N        +G+ TE AL  L  KM +       + + E              
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480

Query: 452 ----YPFSSEQKWMAVKCV----HRTQQDRPEICFMKGAYEQVIKYCTTYQSKGQTLTLT 503
                 FS ++K M+V C     H T Q      F+KGA E VI+ C++ +   +T  LT
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSK--MFVKGAPESVIERCSSVRVGSRTAPLT 538

Query: 504 QQQRDVYQQEKARMGSAG--LRVLALASGP--------ELGQ----------LTFLGLVG 543
              R+    +    GS    LR LALA+          EL            LTF+G VG
Sbjct: 539 PTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVG 598

Query: 544 IIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTS----QSVSGEEI 599
           ++DPPR  V   +T    +G+ + MITGD++ TAVAI  RLG++  T     ++ +G E 
Sbjct: 599 MLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREF 658

Query: 600 DAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGV 659
           D +  +Q  Q       F R  P HK +I+++LQ    + AMTGDGVNDA ALK A+IG+
Sbjct: 659 DDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGI 718

Query: 660 AMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISL 719
           AMG +GT V K AA+M+L DD+F +I++A+EEG+ IY+N+K F+R+ +S+++  +  I L
Sbjct: 719 AMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFL 777

Query: 720 ATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKI 779
             ++  P  L  +Q+LW+N++ DG PA +LG  P D D++ K PR+ ++++++  L  + 
Sbjct: 778 TAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRY 837

Query: 780 LVSSIIIVCGTL------FVF--------WRELRDNVITPRD-----------------T 808
           L   + +   T+      FV+        + +LR+ +    D                 T
Sbjct: 838 LAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPT 897

Query: 809 TMTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVF 868
           TM  +  V  +M NAL+S S+ +S+  +    N     AV  S+    L++  PPL  +F
Sbjct: 898 TMALSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIF 957

Query: 869 QTESLSILDLLFLLGLTSSVCIVAEIIKKVERS 901
           Q   LS    + +L ++  V ++ E +K + R+
Sbjct: 958 QVTPLSGRQWVVVLQISLPVILLDEALKYLSRN 990


>gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo
           sapiens]
          Length = 1043

 Score =  484 bits (1246), Expect = e-136
 Identities = 338/993 (34%), Positives = 516/993 (51%), Gaps = 129/993 (12%)

Query: 29  LPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLL 88
           LP ++V        + GL+  +V+  R  +G NE    E + LW+  + QF++ L+ +LL
Sbjct: 7   LPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILL 66

Query: 89  ASAVISVLMHQFDDAVSITVA-------ILIVVTVAFV---QEYRSEKSLEELSKLVPPE 138
            +A++S ++  F++    T A       +LI+V  A V   QE  +E ++E L +  P  
Sbjct: 67  LAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEM 126

Query: 139 CHCVREGK--LEHTLARDLVPGDTVCLSVGDRVPADLRLFE--AVDLSIDESSLTGETTP 194
              +R  +  ++   ARD+VPGD V ++VGD+VPADLRL E  +  L +D+S LTGE+  
Sbjct: 127 GKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVS 186

Query: 195 CSKVTA--PQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEE 252
            +K T   P P A N D   + N+ F GT +  GKA GV + TG ++E G++   M A E
Sbjct: 187 VTKHTEAIPDPRAVNQD---KKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVE 243

Query: 253 APKTPLQKSMDLLGKQLSFYSFGIIGIIMLV-------------GWLLGKDILEMFTISV 299
             +TPLQ+ +D  G+QLS ++  +I + + V              WL G   +  F I+V
Sbjct: 244 PERTPLQRKLDEFGRQLS-HAISVICVAVWVINIGHFADPAHGGSWLRGA--VYYFKIAV 300

Query: 300 SLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNE 359
           +LAVAAIPEGLP V+T  LALG  RM +K AIV+ LP VETLGC +VICSDKTGTLT N+
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 360 MTVTHIFT-------SDGLHA-EVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVC 411
           M+V  +F        S  LH   ++G  Y   GEV      V       +  +     +C
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420

Query: 412 NDAVIRNNTL------MGKPTEGALIALAMKMGLDGLQQDYIRKAE-------------- 451
           ND+ +  N        +G+ TE AL  L  KM +       + + E              
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480

Query: 452 ----YPFSSEQKWMAVKCV----HRTQQDRPEICFMKGAYEQVIKYCTTYQSKGQTLTLT 503
                 FS ++K M+V C     H T Q      F+KGA E VI+ C++ +   +T  LT
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSK--MFVKGAPESVIERCSSVRVGSRTAPLT 538

Query: 504 QQQRDVYQQEKARMGSAG--LRVLALASGP--------ELGQ----------LTFLGLVG 543
              R+    +    GS    LR LALA+          EL            LTF+G VG
Sbjct: 539 PTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVG 598

Query: 544 IIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTS----QSVSGEEI 599
           ++DPPR  V   +T    +G+ + MITGD++ TAVAI  RLG++  T     ++ +G E 
Sbjct: 599 MLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREF 658

Query: 600 DAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGV 659
           D +  +Q  Q       F R  P HK +I+++LQ    + AMTGDGVNDA ALK A+IG+
Sbjct: 659 DDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGI 718

Query: 660 AMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISL 719
           AMG +GT V K AA+M+L DD+F +I++A+EEG+ IY+N+K F+R+ +S+++  +  I L
Sbjct: 719 AMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFL 777

Query: 720 ATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKI 779
             ++  P  L  +Q+LW+N++ DG PA +LG  P D D++ K PR+ ++++++  L  + 
Sbjct: 778 TAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRY 837

Query: 780 LVSSIIIVCGTL------FVF--------WRELRDNVITPRD-----------------T 808
           L   + +   T+      FV+        + +LR+ +    D                 T
Sbjct: 838 LAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPT 897

Query: 809 TMTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVF 868
           TM  +  V  +M NAL+S S+ +S+  +    N     AV  S+    L++  PPL  +F
Sbjct: 898 TMALSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIF 957

Query: 869 QTESLSILDLLFLLGLTSSVCIVAEIIKKVERS 901
           Q   LS    + +L ++  V ++ E +K + R+
Sbjct: 958 QVTPLSGRQWVVVLQISLPVILLDEALKYLSRN 990


>gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo
           sapiens]
          Length = 1044

 Score =  484 bits (1246), Expect = e-136
 Identities = 338/993 (34%), Positives = 516/993 (51%), Gaps = 129/993 (12%)

Query: 29  LPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLL 88
           LP ++V        + GL+  +V+  R  +G NE    E + LW+  + QF++ L+ +LL
Sbjct: 7   LPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILL 66

Query: 89  ASAVISVLMHQFDDAVSITVA-------ILIVVTVAFV---QEYRSEKSLEELSKLVPPE 138
            +A++S ++  F++    T A       +LI+V  A V   QE  +E ++E L +  P  
Sbjct: 67  LAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEM 126

Query: 139 CHCVREGK--LEHTLARDLVPGDTVCLSVGDRVPADLRLFE--AVDLSIDESSLTGETTP 194
              +R  +  ++   ARD+VPGD V ++VGD+VPADLRL E  +  L +D+S LTGE+  
Sbjct: 127 GKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVS 186

Query: 195 CSKVTA--PQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEE 252
            +K T   P P A N D   + N+ F GT +  GKA GV + TG ++E G++   M A E
Sbjct: 187 VTKHTEAIPDPRAVNQD---KKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVE 243

Query: 253 APKTPLQKSMDLLGKQLSFYSFGIIGIIMLV-------------GWLLGKDILEMFTISV 299
             +TPLQ+ +D  G+QLS ++  +I + + V              WL G   +  F I+V
Sbjct: 244 PERTPLQRKLDEFGRQLS-HAISVICVAVWVINIGHFADPAHGGSWLRGA--VYYFKIAV 300

Query: 300 SLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNE 359
           +LAVAAIPEGLP V+T  LALG  RM +K AIV+ LP VETLGC +VICSDKTGTLT N+
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 360 MTVTHIFT-------SDGLHA-EVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVC 411
           M+V  +F        S  LH   ++G  Y   GEV      V       +  +     +C
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420

Query: 412 NDAVIRNNTL------MGKPTEGALIALAMKMGLDGLQQDYIRKAE-------------- 451
           ND+ +  N        +G+ TE AL  L  KM +       + + E              
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480

Query: 452 ----YPFSSEQKWMAVKCV----HRTQQDRPEICFMKGAYEQVIKYCTTYQSKGQTLTLT 503
                 FS ++K M+V C     H T Q      F+KGA E VI+ C++ +   +T  LT
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSK--MFVKGAPESVIERCSSVRVGSRTAPLT 538

Query: 504 QQQRDVYQQEKARMGSAG--LRVLALASGP--------ELGQ----------LTFLGLVG 543
              R+    +    GS    LR LALA+          EL            LTF+G VG
Sbjct: 539 PTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVG 598

Query: 544 IIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTS----QSVSGEEI 599
           ++DPPR  V   +T    +G+ + MITGD++ TAVAI  RLG++  T     ++ +G E 
Sbjct: 599 MLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREF 658

Query: 600 DAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGV 659
           D +  +Q  Q       F R  P HK +I+++LQ    + AMTGDGVNDA ALK A+IG+
Sbjct: 659 DDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGI 718

Query: 660 AMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISL 719
           AMG +GT V K AA+M+L DD+F +I++A+EEG+ IY+N+K F+R+ +S+++  +  I L
Sbjct: 719 AMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFL 777

Query: 720 ATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKI 779
             ++  P  L  +Q+LW+N++ DG PA +LG  P D D++ K PR+ ++++++  L  + 
Sbjct: 778 TAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRY 837

Query: 780 LVSSIIIVCGTL------FVF--------WRELRDNVITPRD-----------------T 808
           L   + +   T+      FV+        + +LR+ +    D                 T
Sbjct: 838 LAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPT 897

Query: 809 TMTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVF 868
           TM  +  V  +M NAL+S S+ +S+  +    N     AV  S+    L++  PPL  +F
Sbjct: 898 TMALSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIF 957

Query: 869 QTESLSILDLLFLLGLTSSVCIVAEIIKKVERS 901
           Q   LS    + +L ++  V ++ E +K + R+
Sbjct: 958 QVTPLSGRQWVVVLQISLPVILLDEALKYLSRN 990


>gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo
           sapiens]
          Length = 1052

 Score =  484 bits (1246), Expect = e-136
 Identities = 338/993 (34%), Positives = 516/993 (51%), Gaps = 129/993 (12%)

Query: 29  LPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLL 88
           LP ++V        + GL+  +V+  R  +G NE    E + LW+  + QF++ L+ +LL
Sbjct: 7   LPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILL 66

Query: 89  ASAVISVLMHQFDDAVSITVA-------ILIVVTVAFV---QEYRSEKSLEELSKLVPPE 138
            +A++S ++  F++    T A       +LI+V  A V   QE  +E ++E L +  P  
Sbjct: 67  LAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEM 126

Query: 139 CHCVREGK--LEHTLARDLVPGDTVCLSVGDRVPADLRLFE--AVDLSIDESSLTGETTP 194
              +R  +  ++   ARD+VPGD V ++VGD+VPADLRL E  +  L +D+S LTGE+  
Sbjct: 127 GKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVS 186

Query: 195 CSKVTA--PQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEE 252
            +K T   P P A N D   + N+ F GT +  GKA GV + TG ++E G++   M A E
Sbjct: 187 VTKHTEAIPDPRAVNQD---KKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVE 243

Query: 253 APKTPLQKSMDLLGKQLSFYSFGIIGIIMLV-------------GWLLGKDILEMFTISV 299
             +TPLQ+ +D  G+QLS ++  +I + + V              WL G   +  F I+V
Sbjct: 244 PERTPLQRKLDEFGRQLS-HAISVICVAVWVINIGHFADPAHGGSWLRGA--VYYFKIAV 300

Query: 300 SLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNE 359
           +LAVAAIPEGLP V+T  LALG  RM +K AIV+ LP VETLGC +VICSDKTGTLT N+
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 360 MTVTHIFT-------SDGLHA-EVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVC 411
           M+V  +F        S  LH   ++G  Y   GEV      V       +  +     +C
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420

Query: 412 NDAVIRNNTL------MGKPTEGALIALAMKMGLDGLQQDYIRKAE-------------- 451
           ND+ +  N        +G+ TE AL  L  KM +       + + E              
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480

Query: 452 ----YPFSSEQKWMAVKCV----HRTQQDRPEICFMKGAYEQVIKYCTTYQSKGQTLTLT 503
                 FS ++K M+V C     H T Q      F+KGA E VI+ C++ +   +T  LT
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSK--MFVKGAPESVIERCSSVRVGSRTAPLT 538

Query: 504 QQQRDVYQQEKARMGSAG--LRVLALASGP--------ELGQ----------LTFLGLVG 543
              R+    +    GS    LR LALA+          EL            LTF+G VG
Sbjct: 539 PTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVG 598

Query: 544 IIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTS----QSVSGEEI 599
           ++DPPR  V   +T    +G+ + MITGD++ TAVAI  RLG++  T     ++ +G E 
Sbjct: 599 MLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREF 658

Query: 600 DAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGV 659
           D +  +Q  Q       F R  P HK +I+++LQ    + AMTGDGVNDA ALK A+IG+
Sbjct: 659 DDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGI 718

Query: 660 AMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISL 719
           AMG +GT V K AA+M+L DD+F +I++A+EEG+ IY+N+K F+R+ +S+++  +  I L
Sbjct: 719 AMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFL 777

Query: 720 ATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKI 779
             ++  P  L  +Q+LW+N++ DG PA +LG  P D D++ K PR+ ++++++  L  + 
Sbjct: 778 TAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRY 837

Query: 780 LVSSIIIVCGTL------FVF--------WRELRDNVITPRD-----------------T 808
           L   + +   T+      FV+        + +LR+ +    D                 T
Sbjct: 838 LAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPT 897

Query: 809 TMTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVF 868
           TM  +  V  +M NAL+S S+ +S+  +    N     AV  S+    L++  PPL  +F
Sbjct: 898 TMALSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIF 957

Query: 869 QTESLSILDLLFLLGLTSSVCIVAEIIKKVERS 901
           Q   LS    + +L ++  V ++ E +K + R+
Sbjct: 958 QVTPLSGRQWVVVLQISLPVILLDEALKYLSRN 990


>gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [Homo
            sapiens]
          Length = 1042

 Score =  478 bits (1231), Expect = e-135
 Identities = 341/1008 (33%), Positives = 513/1008 (50%), Gaps = 131/1008 (12%)

Query: 31   VSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS 90
            V EV      +   GL+  +V   +   G NE    E + L +  I QF++ L+ +LL +
Sbjct: 9    VEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLA 68

Query: 91   AVISVLMHQFDDA-------VSITVAILIVVTVAFV---QEYRSEKSLEELSKLVPPECH 140
            A IS ++  F++        V   V +LI+V  A V   QE  +E ++E L +  P    
Sbjct: 69   ACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGK 128

Query: 141  CVREGK--LEHTLARDLVPGDTVCLSVGDRVPADLRL--FEAVDLSIDESSLTGETTPCS 196
              R+ +  ++   A+D+VPGD V ++VGD+VPAD+RL   ++  L +D+S LTGE+    
Sbjct: 129  VYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVI 188

Query: 197  KVT--APQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254
            K T   P P A N D   + N+ F GT +  GKA GVV+ TG N+E G++   M A E  
Sbjct: 189  KHTDPVPDPRAVNQD---KKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQE 245

Query: 255  KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLG--------------KDILEMFTISVS 300
            +TPLQ+ +D  G+QLS     +I +I +  W++               +  +  F I+V+
Sbjct: 246  RTPLQQKLDEFGEQLS----KVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVA 301

Query: 301  LAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEM 360
            LAVAAIPEGLP V+T  LALG  RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M
Sbjct: 302  LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361

Query: 361  TVTHIFTSDGLHAE--------VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCN 412
            +V  +F  D +  +        +TG  Y   GEV  D   V+      +  +     +CN
Sbjct: 362  SVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCN 421

Query: 413  DAVIRNNTL------MGKPTEGALIALAMKMG-----LDGLQQ-----------DYIRKA 450
            D+ +  N        +G+ TE AL  L  KM      L GL +             + K 
Sbjct: 422  DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKK 481

Query: 451  EYP--FSSEQKWMAVKCV-HRTQQDRPEICFMKGAYEQVIKYCTTYQSKGQTLTLTQ--Q 505
            E+   FS ++K M+V C  ++  +      F+KGA E VI  CT  +     + +T   +
Sbjct: 482  EFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVK 541

Query: 506  QRDVYQQEKARMGSAGLRVLALASGPEL------------------GQLTFLGLVGIIDP 547
            Q+ +    +   GS  LR LALA+                        LTF+G VG++DP
Sbjct: 542  QKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDP 601

Query: 548  PRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSK----TSQSVSGEEIDAMD 603
            PR  V  +V     +G+ + MITGD++ TAVAI  R+G++ +    TS++ +G E D ++
Sbjct: 602  PRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELN 661

Query: 604  VQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQ 663
                         F R  P HK KI++ LQ    + AMTGDGVNDA ALK A+IG+AMG 
Sbjct: 662  PSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG- 720

Query: 664  TGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLM 723
            +GT V K A++M+L DD+F TI++A+EEG+ IYNN+K F+R+ +S+++  +  I L   +
Sbjct: 721  SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL 780

Query: 724  NFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSS 783
             FP  L  +Q+LW+N++ DG PA +LG  P D D++ KPPRN K+ +++  L  + L   
Sbjct: 781  GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG 840

Query: 784  IIIVCGT---------------------LFVFWRELRDN----------VITPRDTTMTF 812
              +   T                     L  F +   DN            +P   TM  
Sbjct: 841  CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL 900

Query: 813  TCFVFFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTES 872
            +  V  +M NAL+S S+ +S+  +    N     ++  S+    L++Y  PL  +FQ   
Sbjct: 901  SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP 960

Query: 873  LSILDLLFLLGLTSSVCIVAEIIKKVERS-----REKIQKHVSSTSSS 915
            L++   L +L ++  V ++ E +K V R+     +E +Q    S S S
Sbjct: 961  LNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFS 1008


>gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo
           sapiens]
          Length = 997

 Score =  478 bits (1229), Expect = e-134
 Identities = 336/989 (33%), Positives = 506/989 (51%), Gaps = 126/989 (12%)

Query: 31  VSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS 90
           V EV      +   GL+  +V   +   G NE    E + L +  I QF++ L+ +LL +
Sbjct: 9   VEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLA 68

Query: 91  AVISVLMHQFDDA-------VSITVAILIVVTVAFV---QEYRSEKSLEELSKLVPPECH 140
           A IS ++  F++        V   V +LI+V  A V   QE  +E ++E L +  P    
Sbjct: 69  ACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGK 128

Query: 141 CVREGK--LEHTLARDLVPGDTVCLSVGDRVPADLRL--FEAVDLSIDESSLTGETTPCS 196
             R+ +  ++   A+D+VPGD V ++VGD+VPAD+RL   ++  L +D+S LTGE+    
Sbjct: 129 VYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVI 188

Query: 197 KVT--APQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254
           K T   P P A N D   + N+ F GT +  GKA GVV+ TG N+E G++   M A E  
Sbjct: 189 KHTDPVPDPRAVNQD---KKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQE 245

Query: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLG--------------KDILEMFTISVS 300
           +TPLQ+ +D  G+QLS     +I +I +  W++               +  +  F I+V+
Sbjct: 246 RTPLQQKLDEFGEQLS----KVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVA 301

Query: 301 LAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEM 360
           LAVAAIPEGLP V+T  LALG  RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M
Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361

Query: 361 TVTHIFTSDGLHAE--------VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCN 412
           +V  +F  D +  +        +TG  Y   GEV  D   V+      +  +     +CN
Sbjct: 362 SVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCN 421

Query: 413 DAVIRNNTL------MGKPTEGALIALAMKMG-----LDGLQQ-----------DYIRKA 450
           D+ +  N        +G+ TE AL  L  KM      L GL +             + K 
Sbjct: 422 DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKK 481

Query: 451 EYP--FSSEQKWMAVKCV-HRTQQDRPEICFMKGAYEQVIKYCTTYQSKGQTLTLTQ--Q 505
           E+   FS ++K M+V C  ++  +      F+KGA E VI  CT  +     + +T   +
Sbjct: 482 EFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVK 541

Query: 506 QRDVYQQEKARMGSAGLRVLALASGPEL------------------GQLTFLGLVGIIDP 547
           Q+ +    +   GS  LR LALA+                        LTF+G VG++DP
Sbjct: 542 QKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDP 601

Query: 548 PRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSK----TSQSVSGEEIDAMD 603
           PR  V  +V     +G+ + MITGD++ TAVAI  R+G++ +    TS++ +G E D ++
Sbjct: 602 PRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELN 661

Query: 604 VQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQ 663
                        F R  P HK KI++ LQ    + AMTGDGVNDA ALK A+IG+AMG 
Sbjct: 662 PSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG- 720

Query: 664 TGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLM 723
           +GT V K A++M+L DD+F TI++A+EEG+ IYNN+K F+R+ +S+++  +  I L   +
Sbjct: 721 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL 780

Query: 724 NFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSS 783
            FP  L  +Q+LW+N++ DG PA +LG  P D D++ KPPRN K+ +++  L  + L   
Sbjct: 781 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG 840

Query: 784 IIIVCGT---------------------LFVFWRELRDN----------VITPRDTTMTF 812
             +   T                     L  F +   DN            +P   TM  
Sbjct: 841 CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL 900

Query: 813 TCFVFFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTES 872
           +  V  +M NAL+S S+ +S+  +    N     ++  S+    L++Y  PL  +FQ   
Sbjct: 901 SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP 960

Query: 873 LSILDLLFLLGLTSSVCIVAEIIKKVERS 901
           L++   L +L ++  V ++ E +K V R+
Sbjct: 961 LNVTQWLMVLKISLPVILMDETLKFVARN 989


>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b
           [Homo sapiens]
          Length = 994

 Score =  459 bits (1180), Expect = e-129
 Identities = 324/978 (33%), Positives = 498/978 (50%), Gaps = 131/978 (13%)

Query: 45  GLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDA- 103
           GL   +V      +G NE    E + LW+  I QF++ L+ +LL +A IS ++  F++  
Sbjct: 23  GLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWFEEGE 82

Query: 104 ------VSITVAILIVVTVAFV---QEYRSEKSLEELSKLVPPECHCVREGK--LEHTLA 152
                 V   V +LI++  A V   QE  +E ++E L +  P      R  +  ++   A
Sbjct: 83  ETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKA 142

Query: 153 RDLVPGDTVCLSVGDRVPADLRLF--EAVDLSIDESSLTGETTPCSKVT--APQPAATNG 208
           RD+VPGD V ++VGD+VPAD+R+   ++  L +D+S LTGE+    K T   P P A N 
Sbjct: 143 RDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQ 202

Query: 209 DLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQ 268
           D   + N+ F GT +  GKA G+V  TG  +E G++   M A E  KTPLQ+ +D  G+Q
Sbjct: 203 D---KKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQ 259

Query: 269 LSFYSFGIIGIIMLVGWLLG--------------KDILEMFTISVSLAVAAIPEGLPIVV 314
           LS     +I +I +  WL+               +  +  F I+V+LAVAAIPEGLP V+
Sbjct: 260 LS----KVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVI 315

Query: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374
           T  LALG  RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M+V  +F  D +  +
Sbjct: 316 TTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGD 375

Query: 375 V--------TGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTL----- 421
           +        TG  Y   GEV+ +   V       +  +     +CND+ +  N       
Sbjct: 376 ICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNEAKGVYE 435

Query: 422 -MGKPTEGALIALAMKMGLDGLQQDYIRKAE------------------YPFSSEQKWMA 462
            +G+ TE AL  L  KM +       + K E                    FS ++K M+
Sbjct: 436 KVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMS 495

Query: 463 VKCVHRTQQDRPEI---CFMKGAYEQVIKYCTTYQSKGQT---LTLTQQQRDVYQQEKAR 516
           V C    +  R  +    F+KGA E VI  C  Y   G T   LT   +++ +   ++  
Sbjct: 496 VYC-SPAKSSRAAVGNKMFVKGAPEGVIDRCN-YVRVGTTRVPLTGPVKEKIMAVIKEWG 553

Query: 517 MGSAGLRVLALASG---PELGQ---------------LTFLGLVGIIDPPRTGVKEAVTT 558
            G   LR LALA+    P+  +               LTF+G+VG++DPPR  V  ++  
Sbjct: 554 TGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGMLDPPRKEVTGSIQL 613

Query: 559 LIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ----SVSGEEIDAMDVQQLSQIVPKV 614
              +G+ + MITGD++ TA+AI  R+G++ +  +    + +G E D + + +  +   + 
Sbjct: 614 CRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRA 673

Query: 615 AVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAAD 674
             F R  P HK KI++ LQ    + AMTGDGVNDA ALK A+IG+AMG +GT V K A++
Sbjct: 674 CCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASE 732

Query: 675 MILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQI 734
           M+L DD+F TI++A+EEG+ IYNN+K F+R+ +S+++  +  I L   +  P  L  +Q+
Sbjct: 733 MVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQL 792

Query: 735 LWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCGT---- 790
           LW+N++ DG PA +LG  P D D++ +PPR+ K+ +++  L  + +     +   T    
Sbjct: 793 LWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAA 852

Query: 791 -----------------LFVFWRELRDNV----------ITPRDTTMTFTCFVFFDMFNA 823
                            L  F +   DN             P   TM  +  V  +M NA
Sbjct: 853 AWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMCNA 912

Query: 824 LSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLG 883
           L+S S+ +S+  +    N     ++  S+    L++Y  PL  +F+  +L +   L +L 
Sbjct: 913 LNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMVLK 972

Query: 884 LTSSVCIVAEIIKKVERS 901
           ++  V  + EI+K V R+
Sbjct: 973 ISLPVIGLDEILKFVARN 990


>gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a
           [Homo sapiens]
          Length = 1001

 Score =  459 bits (1180), Expect = e-129
 Identities = 324/978 (33%), Positives = 498/978 (50%), Gaps = 131/978 (13%)

Query: 45  GLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDA- 103
           GL   +V      +G NE    E + LW+  I QF++ L+ +LL +A IS ++  F++  
Sbjct: 23  GLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWFEEGE 82

Query: 104 ------VSITVAILIVVTVAFV---QEYRSEKSLEELSKLVPPECHCVREGK--LEHTLA 152
                 V   V +LI++  A V   QE  +E ++E L +  P      R  +  ++   A
Sbjct: 83  ETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKA 142

Query: 153 RDLVPGDTVCLSVGDRVPADLRLF--EAVDLSIDESSLTGETTPCSKVT--APQPAATNG 208
           RD+VPGD V ++VGD+VPAD+R+   ++  L +D+S LTGE+    K T   P P A N 
Sbjct: 143 RDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQ 202

Query: 209 DLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQ 268
           D   + N+ F GT +  GKA G+V  TG  +E G++   M A E  KTPLQ+ +D  G+Q
Sbjct: 203 D---KKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQ 259

Query: 269 LSFYSFGIIGIIMLVGWLLG--------------KDILEMFTISVSLAVAAIPEGLPIVV 314
           LS     +I +I +  WL+               +  +  F I+V+LAVAAIPEGLP V+
Sbjct: 260 LS----KVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVI 315

Query: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374
           T  LALG  RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M+V  +F  D +  +
Sbjct: 316 TTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGD 375

Query: 375 V--------TGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTL----- 421
           +        TG  Y   GEV+ +   V       +  +     +CND+ +  N       
Sbjct: 376 ICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNEAKGVYE 435

Query: 422 -MGKPTEGALIALAMKMGLDGLQQDYIRKAE------------------YPFSSEQKWMA 462
            +G+ TE AL  L  KM +       + K E                    FS ++K M+
Sbjct: 436 KVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMS 495

Query: 463 VKCVHRTQQDRPEI---CFMKGAYEQVIKYCTTYQSKGQT---LTLTQQQRDVYQQEKAR 516
           V C    +  R  +    F+KGA E VI  C  Y   G T   LT   +++ +   ++  
Sbjct: 496 VYC-SPAKSSRAAVGNKMFVKGAPEGVIDRCN-YVRVGTTRVPLTGPVKEKIMAVIKEWG 553

Query: 517 MGSAGLRVLALASG---PELGQ---------------LTFLGLVGIIDPPRTGVKEAVTT 558
            G   LR LALA+    P+  +               LTF+G+VG++DPPR  V  ++  
Sbjct: 554 TGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGMLDPPRKEVTGSIQL 613

Query: 559 LIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ----SVSGEEIDAMDVQQLSQIVPKV 614
              +G+ + MITGD++ TA+AI  R+G++ +  +    + +G E D + + +  +   + 
Sbjct: 614 CRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRA 673

Query: 615 AVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAAD 674
             F R  P HK KI++ LQ    + AMTGDGVNDA ALK A+IG+AMG +GT V K A++
Sbjct: 674 CCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASE 732

Query: 675 MILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQI 734
           M+L DD+F TI++A+EEG+ IYNN+K F+R+ +S+++  +  I L   +  P  L  +Q+
Sbjct: 733 MVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQL 792

Query: 735 LWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCGT---- 790
           LW+N++ DG PA +LG  P D D++ +PPR+ K+ +++  L  + +     +   T    
Sbjct: 793 LWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAA 852

Query: 791 -----------------LFVFWRELRDNV----------ITPRDTTMTFTCFVFFDMFNA 823
                            L  F +   DN             P   TM  +  V  +M NA
Sbjct: 853 AWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMCNA 912

Query: 824 LSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLG 883
           L+S S+ +S+  +    N     ++  S+    L++Y  PL  +F+  +L +   L +L 
Sbjct: 913 LNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMVLK 972

Query: 884 LTSSVCIVAEIIKKVERS 901
           ++  V  + EI+K V R+
Sbjct: 973 ISLPVIGLDEILKFVARN 990


>gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3
           [Homo sapiens]
          Length = 1015

 Score =  442 bits (1136), Expect = e-124
 Identities = 326/1004 (32%), Positives = 494/1004 (49%), Gaps = 150/1004 (14%)

Query: 31  VSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS 90
           V EV      +   GL+  +V   +   G NE    E + L +  I QF++ L+ +LL +
Sbjct: 9   VEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLA 68

Query: 91  AVISVLMHQFDDA-------VSITVAILIVVTVAFV---QEYRSEKSLEELSKLVPPECH 140
           A IS ++  F++        V   V +LI+V  A V   QE  +E ++E L +  P    
Sbjct: 69  ACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGK 128

Query: 141 CVREGK--LEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKV 198
             R+ +  ++   A+D+VPGD V                  +++ +  S+   T P    
Sbjct: 129 VYRQDRKSVQRIKAKDIVPGDIV------------------EIAGESVSVIKHTDP---- 166

Query: 199 TAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPL 258
             P P A N D   + N+ F GT +  GKA GVV+ TG N+E G++   M A E  +TPL
Sbjct: 167 -VPDPRAVNQD---KKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPL 222

Query: 259 QKSMDLLGKQLSFYSFGIIGIIMLVGWLLG--------------KDILEMFTISVSLAVA 304
           Q+ +D  G+QLS     +I +I +  W++               +  +  F I+V+LAVA
Sbjct: 223 QQKLDEFGEQLS----KVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVA 278

Query: 305 AIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTH 364
           AIPEGLP V+T  LALG  RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M+V  
Sbjct: 279 AIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCR 338

Query: 365 IFTSDGLHAE--------VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVI 416
           +F  D +  +        +TG  Y   GEV  D   V+      +  +     +CND+ +
Sbjct: 339 MFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSAL 398

Query: 417 RNNTL------MGKPTEGALIALAMKMG-----LDGLQQ-----------DYIRKAEYP- 453
             N        +G+ TE AL  L  KM      L GL +             + K E+  
Sbjct: 399 DYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTL 458

Query: 454 -FSSEQKWMAVKCV-HRTQQDRPEICFMKGAYEQVIKYCTTYQSKGQTLTLTQ--QQRDV 509
            FS ++K M+V C  ++  +      F+KGA E VI  CT  +     + +T   +Q+ +
Sbjct: 459 EFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVKQKIM 518

Query: 510 YQQEKARMGSAGLRVLALASGPEL------------------GQLTFLGLVGIIDPPRTG 551
               +   GS  LR LALA+                        LTF+G VG++DPPR  
Sbjct: 519 SVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIE 578

Query: 552 VKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSK----TSQSVSGEEIDAMDVQQL 607
           V  +V     +G+ + MITGD++ TAVAI  R+G++ +    TS++ +G E D ++    
Sbjct: 579 VASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQ 638

Query: 608 SQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTD 667
                    F R  P HK KI++ LQ    + AMTGDGVNDA ALK A+IG+AMG +GT 
Sbjct: 639 RDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTA 697

Query: 668 VCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPN 727
           V K A++M+L DD+F TI++A+EEG+ IYNN+K F+R+ +S+++  +  I L   + FP 
Sbjct: 698 VAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPE 757

Query: 728 PLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIV 787
            L  +Q+LW+N++ DG PA +LG  P D D++ KPPRN K+ +++  L  + L     + 
Sbjct: 758 ALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVG 817

Query: 788 CGT---------------------LFVFWRELRDN----------VITPRDTTMTFTCFV 816
             T                     L  F +   DN            +P   TM  +  V
Sbjct: 818 AATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLV 877

Query: 817 FFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSIL 876
             +M NAL+S S+ +S+  +    N     ++  S+    L++Y  PL  +FQ   L++ 
Sbjct: 878 TIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVT 937

Query: 877 DLLFLLGLTSSVCIVAEIIKKVERS-----REKIQKHVSSTSSS 915
             L +L ++  V ++ E +K V R+     +E +Q    S S S
Sbjct: 938 QWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFS 981


>gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]
          Length = 1013

 Score =  376 bits (965), Expect = e-104
 Identities = 269/849 (31%), Positives = 422/849 (49%), Gaps = 84/849 (9%)

Query: 28  ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87
           ++ V EV      D   GL   +     A  G N        P W K+  Q      +LL
Sbjct: 35  KMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSILL 94

Query: 88  LASAVISVLMHQF-----DDA------VSITVAILIVVTVAF--VQEYRSEKSLEELSKL 134
              A++  L +       DD       + I +A ++++T  F   QE +S K +E    +
Sbjct: 95  WIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNM 154

Query: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194
           VP +   +REG+     A ++V GD V +  GDRVPADLR+  A    +D SSLTGE+ P
Sbjct: 155 VPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEP 214

Query: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254
            ++     P  T+ +     NI F  T    G A+GVV+ TG+ +  G +  +    E  
Sbjct: 215 QTR----SPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASGLEVG 270

Query: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314
           KTP+   ++   + ++  +  +     ++  +LG   LE     + + VA +PEGL   V
Sbjct: 271 KTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVIFLIGIIVANVPEGLLATV 330

Query: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374
           TV L L   RM +K  +VK L  VETLG  + ICSDKTGTLT+N MTV H++  + +H  
Sbjct: 331 TVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEA 390

Query: 375 VT-----GVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGA 429
            T     G  +++     V    + G  N AV +    G   N  V++ + + G  +E A
Sbjct: 391 DTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFK----GGQDNIPVLKRD-VAGDASESA 445

Query: 430 LI-ALAMKMGLDGLQQDYIRK-AEYPFSSEQKWMAVKCVHRTQQ--DRPEICFMKGAYEQ 485
           L+  + +  G   L ++  +K AE PF+S  K+     +H T+   D   +  MKGA E+
Sbjct: 446 LLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQL--SIHETEDPNDNRYLLVMKGAPER 503

Query: 486 VIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASG--PE----------- 532
           ++  C+T   +G+   L ++ ++ +Q     +G  G RVL       PE           
Sbjct: 504 ILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDC 563

Query: 533 ------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL 586
                    L F+GL+ +IDPPR  V +AV    ++G+ + M+TGD   TA AIA  +G+
Sbjct: 564 DDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGI 623

Query: 587 YSKTSQSVSGEEIDAMDVQQLSQIVPKVA----------------------------VFY 618
            S+ +++V  E+I A     +SQ+ P+ A                            VF 
Sbjct: 624 ISEGNETV--EDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFA 681

Query: 619 RASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILV 678
           R SP+ K+ I++  Q+ G++VA+TGDGVND+ ALK ADIGVAMG  G+DV K+AADMIL+
Sbjct: 682 RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 741

Query: 679 DDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWIN 738
           DD+F +I++ +EEG+ I++N+K  + + L+++I  +T   L  + N P PL  + IL I+
Sbjct: 742 DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCID 801

Query: 739 IIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGTLFVFWR 796
           +  D  PA SL  E  + D++++ PRN +   L    ++ +    I  I   G  F ++ 
Sbjct: 802 LGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGFFSYFV 861

Query: 797 ELRDNVITP 805
            L +N   P
Sbjct: 862 ILAENGFLP 870


>gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]
          Length = 1020

 Score =  375 bits (964), Expect = e-104
 Identities = 266/847 (31%), Positives = 426/847 (50%), Gaps = 81/847 (9%)

Query: 28  ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87
           +L + E+    Q DL  GL         A  G N        P W K+  Q      +LL
Sbjct: 43  KLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILL 102

Query: 88  LASAVISVLMHQFDDAVS-----------ITVAILIVVTVAF--VQEYRSEKSLEELSKL 134
              A++  L +    A+            + +A +++VT  F   QE +S K ++    +
Sbjct: 103 WIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNM 162

Query: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194
           VP +   +REG+     A ++V GD V +  GDRVPADLR+  +    +D SSLTGE+ P
Sbjct: 163 VPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEP 222

Query: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254
            ++     P  T+ +     NI F  T    G A+G+VI TG+ +  G +  +    E  
Sbjct: 223 QTR----SPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVG 278

Query: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314
           +TP+   ++   + ++  +  +     ++  +LG   LE     + + VA +PEGL   V
Sbjct: 279 RTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATV 338

Query: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374
           TV L L   RM +K  +VK L  VETLG  + ICSDKTGTLT+N MTV H++  + +H  
Sbjct: 339 TVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEA 398

Query: 375 VT-----GVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGA 429
            T     G  +++          + G  N AV +  +     N +V + +T  G  +E A
Sbjct: 399 DTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQE----NISVSKRDTA-GDASESA 453

Query: 430 LI-ALAMKMGLDGLQQDYIRK-AEYPFSSEQKWMAVKCVHRTQQDRPE--ICFMKGAYEQ 485
           L+  + +  G     +D   K AE PF+S  K+     +H  ++D P+  +  MKGA E+
Sbjct: 454 LLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQL--SIHE-REDSPQSHVLVMKGAPER 510

Query: 486 VIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLA-----LASGP--------- 531
           ++  C+T   +G+ + L ++ +D +Q     +G  G RVL      L SG          
Sbjct: 511 ILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDT 570

Query: 532 -ELG----QLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL 586
            EL     +L F+GL+ +IDPPR  V +AV    ++G+ + M+TGD   TA AIA  +G+
Sbjct: 571 DELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGI 630

Query: 587 YSKTSQSVS------------------------GEEIDAMDVQQLSQIVPKVA--VFYRA 620
            S+ +++V                         G ++  M  +QL +I+      VF R 
Sbjct: 631 ISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFART 690

Query: 621 SPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDD 680
           SP+ K+ I++  Q+ G++VA+TGDGVND+ ALK ADIG+AMG +G+DV K+AADMIL+DD
Sbjct: 691 SPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDD 750

Query: 681 DFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINII 740
           +F +I++ +EEG+ I++N+K  + + L+++I  +T   L  + N P PL  + IL I++ 
Sbjct: 751 NFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLG 810

Query: 741 MDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGTLFVFWREL 798
            D  PA SL  E  + D++++ PRN +   L    ++ +    I  I   G  F ++  L
Sbjct: 811 TDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVIL 870

Query: 799 RDNVITP 805
            +N   P
Sbjct: 871 AENGFLP 877


>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo
           sapiens]
          Length = 1023

 Score =  372 bits (954), Expect = e-102
 Identities = 269/855 (31%), Positives = 419/855 (49%), Gaps = 96/855 (11%)

Query: 28  ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87
           +L + E+      DL  GL     +   A  G N        P W K+  Q      MLL
Sbjct: 45  KLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSMLL 104

Query: 88  LASAVISVLMHQFDDA-------------VSITVAILIVVTVAFVQEYRSEKSLEELSKL 134
              A++  L +    A             V ++  ++I    ++ QE +S K +E    +
Sbjct: 105 WIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNM 164

Query: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194
           VP +   +R G+     A ++V GD V +  GDR+PADLR+  A    +D SSLTGE+ P
Sbjct: 165 VPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEP 224

Query: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254
            ++     P  TN +     NIAF  T    G A+G+V+ TG+ +  G +  +    E  
Sbjct: 225 QTR----SPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGG 280

Query: 255 KTPLQKSMD-----LLGKQLSF-YSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPE 308
           +TP+   ++     + G  +    SF I+ +I+   WL      E     + + VA +PE
Sbjct: 281 QTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWL------EAVIFLIGIIVANVPE 334

Query: 309 GLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTS 368
           GL   VTV L L   RM +K  +VK L  VETLG  + ICSDKTGTLT+N MTV H++  
Sbjct: 335 GLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD 394

Query: 369 DGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNN--------- 419
           + +H   T    NQ G   V  D     +  A+SRI  AG +CN AV + N         
Sbjct: 395 NQIHEADTTE--NQSG---VSFDKTSATWL-ALSRI--AG-LCNRAVFQANQENLPILKR 445

Query: 420 TLMGKPTEGALI-ALAMKMG-LDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEIC 477
            + G  +E AL+  + +  G +  +++ Y +  E PF+S  K+      +    +   + 
Sbjct: 446 AVAGDASESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLL 505

Query: 478 FMKGAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALA-------SG 530
            MKGA E+++  C++    G+   L ++ +D +Q     +G  G RVL            
Sbjct: 506 VMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQF 565

Query: 531 PE------------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAV 578
           PE            +  L F+GL+ +IDPPR  V +AV    ++G+ + M+TGD   TA 
Sbjct: 566 PEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAK 625

Query: 579 AIASRLGLYSKTSQSVS------------------------GEEIDAMDVQQLSQIVP-- 612
           AIA  +G+ S+ +++V                         G ++  M  +QL  I+   
Sbjct: 626 AIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYH 685

Query: 613 KVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEA 672
              VF R SP+ K+ I++  Q+ G++VA+TGDGVND+ ALK ADIGVAMG  G+DV K+A
Sbjct: 686 TEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQA 745

Query: 673 ADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAM 732
           ADMIL+DD+F +I++ +EEG+ I++N+K  + + L+++I  +T   +  + N P PL  +
Sbjct: 746 ADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTV 805

Query: 733 QILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGT 790
            IL I++  D  PA SL  E  + D++++ PRN K   L    ++ +    I  I   G 
Sbjct: 806 TILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGG 865

Query: 791 LFVFWRELRDNVITP 805
            F ++  L +N   P
Sbjct: 866 FFTYFVILAENGFLP 880


>gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo
           sapiens]
          Length = 992

 Score =  372 bits (954), Expect = e-102
 Identities = 269/855 (31%), Positives = 419/855 (49%), Gaps = 96/855 (11%)

Query: 28  ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87
           +L + E+      DL  GL     +   A  G N        P W K+  Q      MLL
Sbjct: 14  KLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSMLL 73

Query: 88  LASAVISVLMHQFDDA-------------VSITVAILIVVTVAFVQEYRSEKSLEELSKL 134
              A++  L +    A             V ++  ++I    ++ QE +S K +E    +
Sbjct: 74  WIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNM 133

Query: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194
           VP +   +R G+     A ++V GD V +  GDR+PADLR+  A    +D SSLTGE+ P
Sbjct: 134 VPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEP 193

Query: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254
            ++     P  TN +     NIAF  T    G A+G+V+ TG+ +  G +  +    E  
Sbjct: 194 QTR----SPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGG 249

Query: 255 KTPLQKSMD-----LLGKQLSF-YSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPE 308
           +TP+   ++     + G  +    SF I+ +I+   WL      E     + + VA +PE
Sbjct: 250 QTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWL------EAVIFLIGIIVANVPE 303

Query: 309 GLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTS 368
           GL   VTV L L   RM +K  +VK L  VETLG  + ICSDKTGTLT+N MTV H++  
Sbjct: 304 GLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD 363

Query: 369 DGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNN--------- 419
           + +H   T    NQ G   V  D     +  A+SRI  AG +CN AV + N         
Sbjct: 364 NQIHEADTTE--NQSG---VSFDKTSATWL-ALSRI--AG-LCNRAVFQANQENLPILKR 414

Query: 420 TLMGKPTEGALI-ALAMKMG-LDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEIC 477
            + G  +E AL+  + +  G +  +++ Y +  E PF+S  K+      +    +   + 
Sbjct: 415 AVAGDASESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLL 474

Query: 478 FMKGAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALA-------SG 530
            MKGA E+++  C++    G+   L ++ +D +Q     +G  G RVL            
Sbjct: 475 VMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQF 534

Query: 531 PE------------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAV 578
           PE            +  L F+GL+ +IDPPR  V +AV    ++G+ + M+TGD   TA 
Sbjct: 535 PEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAK 594

Query: 579 AIASRLGLYSKTSQSVS------------------------GEEIDAMDVQQLSQIVP-- 612
           AIA  +G+ S+ +++V                         G ++  M  +QL  I+   
Sbjct: 595 AIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYH 654

Query: 613 KVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEA 672
              VF R SP+ K+ I++  Q+ G++VA+TGDGVND+ ALK ADIGVAMG  G+DV K+A
Sbjct: 655 TEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQA 714

Query: 673 ADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAM 732
           ADMIL+DD+F +I++ +EEG+ I++N+K  + + L+++I  +T   +  + N P PL  +
Sbjct: 715 ADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTV 774

Query: 733 QILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGT 790
            IL I++  D  PA SL  E  + D++++ PRN K   L    ++ +    I  I   G 
Sbjct: 775 TILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGG 834

Query: 791 LFVFWRELRDNVITP 805
            F ++  L +N   P
Sbjct: 835 FFTYFVILAENGFLP 849


>gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]
          Length = 1023

 Score =  372 bits (954), Expect = e-102
 Identities = 269/855 (31%), Positives = 419/855 (49%), Gaps = 96/855 (11%)

Query: 28  ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87
           +L + E+      DL  GL     +   A  G N        P W K+  Q      MLL
Sbjct: 45  KLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSMLL 104

Query: 88  LASAVISVLMHQFDDA-------------VSITVAILIVVTVAFVQEYRSEKSLEELSKL 134
              A++  L +    A             V ++  ++I    ++ QE +S K +E    +
Sbjct: 105 WIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNM 164

Query: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194
           VP +   +R G+     A ++V GD V +  GDR+PADLR+  A    +D SSLTGE+ P
Sbjct: 165 VPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEP 224

Query: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254
            ++     P  TN +     NIAF  T    G A+G+V+ TG+ +  G +  +    E  
Sbjct: 225 QTR----SPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGG 280

Query: 255 KTPLQKSMD-----LLGKQLSF-YSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPE 308
           +TP+   ++     + G  +    SF I+ +I+   WL      E     + + VA +PE
Sbjct: 281 QTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWL------EAVIFLIGIIVANVPE 334

Query: 309 GLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTS 368
           GL   VTV L L   RM +K  +VK L  VETLG  + ICSDKTGTLT+N MTV H++  
Sbjct: 335 GLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD 394

Query: 369 DGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNN--------- 419
           + +H   T    NQ G   V  D     +  A+SRI  AG +CN AV + N         
Sbjct: 395 NQIHEADTTE--NQSG---VSFDKTSATWL-ALSRI--AG-LCNRAVFQANQENLPILKR 445

Query: 420 TLMGKPTEGALI-ALAMKMG-LDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEIC 477
            + G  +E AL+  + +  G +  +++ Y +  E PF+S  K+      +    +   + 
Sbjct: 446 AVAGDASESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLL 505

Query: 478 FMKGAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALA-------SG 530
            MKGA E+++  C++    G+   L ++ +D +Q     +G  G RVL            
Sbjct: 506 VMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQF 565

Query: 531 PE------------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAV 578
           PE            +  L F+GL+ +IDPPR  V +AV    ++G+ + M+TGD   TA 
Sbjct: 566 PEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAK 625

Query: 579 AIASRLGLYSKTSQSVS------------------------GEEIDAMDVQQLSQIVP-- 612
           AIA  +G+ S+ +++V                         G ++  M  +QL  I+   
Sbjct: 626 AIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYH 685

Query: 613 KVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEA 672
              VF R SP+ K+ I++  Q+ G++VA+TGDGVND+ ALK ADIGVAMG  G+DV K+A
Sbjct: 686 TEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQA 745

Query: 673 ADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAM 732
           ADMIL+DD+F +I++ +EEG+ I++N+K  + + L+++I  +T   +  + N P PL  +
Sbjct: 746 ADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTV 805

Query: 733 QILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGT 790
            IL I++  D  PA SL  E  + D++++ PRN K   L    ++ +    I  I   G 
Sbjct: 806 TILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGG 865

Query: 791 LFVFWRELRDNVITP 805
            F ++  L +N   P
Sbjct: 866 FFTYFVILAENGFLP 880


>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo
           sapiens]
          Length = 1029

 Score =  363 bits (932), Expect = e-100
 Identities = 258/850 (30%), Positives = 422/850 (49%), Gaps = 84/850 (9%)

Query: 28  ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87
           +L + E+++    DL  G +           G N        P W K+  Q      +LL
Sbjct: 53  KLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLLL 112

Query: 88  LASAVISVLMHQ----FDDA-------VSITVAILIVVTVAF--VQEYRSEKSLEELSKL 134
              A++  + +     F++        +SI ++++++VT  F   QE +S K +E    +
Sbjct: 113 WTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFKNM 172

Query: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194
           VP +   +R G+      +++V GD V +  GDRVPADLRL  A    +D SSLTGE+ P
Sbjct: 173 VPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLISAQGCKVDNSSLTGESEP 232

Query: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254
            S+     P  T+ +     NI F  T    G A+G+VI TG+++  G +  +       
Sbjct: 233 QSR----SPDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLTSGLAVG 288

Query: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314
           +TP+   ++     ++  +  +      +  LLG   LE     + + VA +PEGL   V
Sbjct: 289 QTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIGIIVANVPEGLLATV 348

Query: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHA- 373
           TV L L   RM +K  +VK L  VETLG  + ICSDKTGTLT+N MTV H++    ++  
Sbjct: 349 TVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDMTVYEA 408

Query: 374 ----EVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAV--IRNNTLMGKPTE 427
               E TG  + +  +       + G  N A  +        N  +  I      G  +E
Sbjct: 409 DTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFK-------ANQEILPIAKRATTGDASE 461

Query: 428 GALIALAMKM--GLDGLQQDYIRKAEYPFSSEQKWMAVKCVH-RTQQDRPEICFMKGAYE 484
            AL+    +    +  +++   + AE PF+S  K+     +H R    +  +  MKGA E
Sbjct: 462 SALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQM--SIHLREDSSQTHVLMMKGAPE 519

Query: 485 QVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLA-----LASGPELG----- 534
           +++++C+T+   GQ  ++  + ++ +Q     +G  G RVL      L S    G     
Sbjct: 520 RILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNLPSSFSKGFPFNT 579

Query: 535 --------QLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL 586
                    L F+GL+ +IDPPR  V +AV+   ++G+ + M+TGD   TA AIA  +G+
Sbjct: 580 DEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGI 639

Query: 587 YSKTSQS------------------------VSGEEIDAMDVQQLSQIV---PKVAVFYR 619
            S+ +++                        V G E+  +  +QL QI+   P++ VF R
Sbjct: 640 ISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEI-VFAR 698

Query: 620 ASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVD 679
            SP+ K+ I++  Q+ G+VVA+TGDGVND+ ALK ADIG+AMG +G+DV K+AADMIL+D
Sbjct: 699 TSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLD 758

Query: 680 DDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINI 739
           D+F +I++ +EEG+ I++N+K  + + L+++I  +T   +  ++  P PL  + IL I++
Sbjct: 759 DNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDL 818

Query: 740 IMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGTLFVFWRE 797
             D  PA SL  E  + D++++ PRN K   L  + ++ +    I  I      F ++  
Sbjct: 819 GTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALAGFFTYFVI 878

Query: 798 LRDNVITPRD 807
           L +N   P D
Sbjct: 879 LAENGFRPVD 888


>gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]
          Length = 1035

 Score =  356 bits (913), Expect = 6e-98
 Identities = 252/811 (31%), Positives = 400/811 (49%), Gaps = 86/811 (10%)

Query: 28  ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87
           +L V+E+    Q     GL+    +      G N        P + K+  Q    L  L+
Sbjct: 56  QLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLM 115

Query: 88  LASAVISVLMHQF---------DDAVSITVAILIVVTVA----FVQEYRSEKSLEELSKL 134
             +A I ++             DD + + +A++ VV V     + QE++S   +     L
Sbjct: 116 WVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNL 175

Query: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194
           VP +   +R+G      A  LV GD V +  GDRVPAD+R+  A    +D SSLTGE+ P
Sbjct: 176 VPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEP 235

Query: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254
            ++     P  T+       NIAF  T+   G  +G+V+ TG+ +  G +  +    E  
Sbjct: 236 QTR----SPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENE 291

Query: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314
           KTP+   ++     ++  +        +V   +G   L      +++ VA +PEGL   V
Sbjct: 292 KTPIAIEIEHFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATV 351

Query: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374
           TV L+L   R+  K  +VK L  VETLG  +VICSDKTGTLT+N MTV+H++  + +H  
Sbjct: 352 TVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTA 411

Query: 375 VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNT---------LMGKP 425
            T    +Q G+              A+ R++    +CN A  ++           ++G  
Sbjct: 412 DTTE--DQSGQTFDQSSETWR----ALCRVLT---LCNRAAFKSGQDAVPVPKRIVIGDA 462

Query: 426 TEGALIALA-MKMG-LDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAY 483
           +E AL+  + + +G   G +  + +  E PF+S  K+          +D   +  MKGA 
Sbjct: 463 SETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAP 522

Query: 484 EQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALA--------------- 528
           E+V++ C++   KGQ L L +Q R+ +Q     +G  G RVL                  
Sbjct: 523 ERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAF 582

Query: 529 -----SGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASR 583
                + P  G L F GLV +IDPPR  V +AV     +G+ + M+TGD   TA AIA+ 
Sbjct: 583 DVEAMNFPSSG-LCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAAS 641

Query: 584 LGLYSKTSQSV------------------------SGEEIDAMDVQQLSQIV---PKVAV 616
           +G+ S+ S++V                        +G ++  MD  +L + +   P++ V
Sbjct: 642 VGIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEM-V 700

Query: 617 FYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMI 676
           F R SP+ K+ I++S Q+ G++VA+TGDGVND+ ALK ADIGVAMG  G+D  K AADMI
Sbjct: 701 FARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMI 760

Query: 677 LVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILW 736
           L+DD+F +I++ +E+G+ I++N+K  + + L+ +I  LT   +   ++ P PL  + IL+
Sbjct: 761 LLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILF 820

Query: 737 INIIMDGPPAQSLGVEPVDKDVIRKPPRNWK 767
           I +  D  P+ SL  E  + D++   PRN K
Sbjct: 821 IELCTDIFPSVSLAYEKAESDIMHLRPRNPK 851


>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
          Length = 1039

 Score =  326 bits (836), Expect = 5e-89
 Identities = 246/847 (29%), Positives = 408/847 (48%), Gaps = 104/847 (12%)

Query: 41  DLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVL---- 96
           D+  GL+    +   A  G N     +  P   K++ Q      +LL   A +  +    
Sbjct: 73  DIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILLWVGAFLCWIAYGI 132

Query: 97  MHQFDDAVSIT-------VAILIVVT--VAFVQEYRSEKSLEELSKLVPPECHCVREGKL 147
            +  D + S+        + +++++T   A+ QE +S   +   +K++P +   +R+ + 
Sbjct: 133 QYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEK 192

Query: 148 EHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP---CSKVTAPQPA 204
           +   +  LV GD V +  GD++PAD+R+  +    +D SSLTGE+ P    S+ T   P 
Sbjct: 193 KTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPL 252

Query: 205 ATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDL 264
            T        NI F  T    G   G+VI TG+ +  G +  +       KTP+   ++ 
Sbjct: 253 ETK-------NICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEH 305

Query: 265 LGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMR 324
               ++  +  I  +  ++   L   +L+     + + VA +PEGL   VTVTL+L   R
Sbjct: 306 FVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKR 365

Query: 325 MVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQFG 384
           M KK  +VK L  VETLG  ++ICSDKTGTLT+N MTV H++  + +    T   ++   
Sbjct: 366 MAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHSN-- 423

Query: 385 EVIVDGDVVHGFYNPAVSRIVEAGCVCNDAV---------IRNNTLMGKPTEGALIALAM 435
           +V             ++S+I+    +CN A          I    ++G  +E AL+  + 
Sbjct: 424 QVFDQSSRTWA----SLSKIIT---LCNRAEFKPGQENVPIMKKAVIGDASETALLKFSE 476

Query: 436 KMGLDGLQQDYIRK-----AEYPFSSEQKWMAVKCVHRTQQDRPE----ICFMKGAYEQV 486
            +  D ++   IRK     AE PF+S  K+     +H  + D P     +  MKGA E++
Sbjct: 477 VILGDVME---IRKRNRKVAEIPFNSTNKFQL--SIH--EMDDPHGKRFLMVMKGAPERI 529

Query: 487 IKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALA-------SGPEL------ 533
           ++ C+T    G+   L +     +      +G  G RVL            PE       
Sbjct: 530 LEKCSTIMINGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDID 589

Query: 534 ------GQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLY 587
                   L F+GL+ +IDPPR+ V +AVT   ++G+ + M+TGD   TA AIA  +G+ 
Sbjct: 590 AMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGII 649

Query: 588 SKTSQSV------------------------SGEEIDAMDVQQLSQIVPKVA--VFYRAS 621
           S  S++V                        +G E+  M  +QL +I+      VF R S
Sbjct: 650 SANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTS 709

Query: 622 PRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDD 681
           P+ K+ I++  Q+  +VVA+TGDGVND+ ALK ADIG+AMG  G+D  K AADM+L+DD+
Sbjct: 710 PQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDN 769

Query: 682 FQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIM 741
           F +I++ +EEG+ I++N+K  + + L+ +IA L    +  ++  P P+  + IL+I++  
Sbjct: 770 FASIVTGVEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGT 829

Query: 742 DGPPAQSLGVEPVDKDVI-RKPPRNWKDSILTKNL-ILKILVSSIIIVCGTLFVFWRELR 799
           D  P+ +L  E  + D++ RKP    KD ++ + L +   L   ++   G   V++    
Sbjct: 830 DIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYFTVYA 889

Query: 800 DNVITPR 806
                PR
Sbjct: 890 QEGFLPR 896


>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
            sapiens]
          Length = 1220

 Score =  300 bits (769), Expect = 3e-81
 Identities = 257/929 (27%), Positives = 431/929 (46%), Gaps = 140/929 (15%)

Query: 102  DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--CVREGKLEHTLARDLVPGD 159
            +  +I ++++ VV V    ++  EK    L   +  E     +R G+L       LV GD
Sbjct: 156  EGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGD 215

Query: 160  TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFM 219
               +  GD +PAD  L +A DL IDESSLTGE+    K     P   +G      +   +
Sbjct: 216  IAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMV 275

Query: 220  GTLVRCGKAKGVV---IGTG---------------------------------------E 237
             T V      G++   +G G                                       +
Sbjct: 276  VTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLK 335

Query: 238  NSEFGEVF----KMMQAEEAPKTPLQKSMDLLGKQLS---FYSFGIIGIIMLVGWLLGKD 290
            ++E GE+     K   A +  K+ LQ  +  L  Q+         I  II+++ +++   
Sbjct: 336  SAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETF 395

Query: 291  ILE------------------MFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIV 332
            ++E                   F I V++ V A+PEGLP+ VT++LA  V +M+K   +V
Sbjct: 396  VVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLV 455

Query: 333  KKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGY--NQFGEVIVDG 390
            + L   ET+G    ICSDKTGTLT N MTV   +  D  + E+        +  +++V  
Sbjct: 456  RHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHA 515

Query: 391  DVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLD------GLQQ 444
              ++  Y   +    + G +           +G  TE AL+   + +  D       + +
Sbjct: 516  ISINSAYTTKILPPEKEGALPRQ--------VGNKTECALLGFVLDLKRDFQPVREQIPE 567

Query: 445  DYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTY-QSKGQTLTLT 503
            D + K  Y F+S +K M+         D     F KGA E ++K CT    S G+     
Sbjct: 568  DKLYKV-YTFNSVRKSMSTVI---RMPDGGFRLFSKGASEILLKKCTNILNSNGELRGFR 623

Query: 504  QQQRD-VYQQEKARMGSAGLRVLALA-----SGPE---------LGQLTFLGLVGIIDPP 548
             + RD + ++    M   GLR + +A     +G E         +G LT + +VGI DP 
Sbjct: 624  PRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPV 683

Query: 549  RTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ--SVSGEEIDA----- 601
            R  V EA+     +G++++M+TGD+  TA AIA++ G+         + G+E +      
Sbjct: 684  RPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNE 743

Query: 602  ---MDVQQLSQIVPKVAVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDGVNDAVALK 653
               ++ ++L ++ PK+ V  R+SP  K  ++K +      +   VVA+TGDG ND  ALK
Sbjct: 744  KGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALK 803

Query: 654  AADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAA 713
             AD+G AMG  GTDV KEA+D+IL DD+F +I+ A+  G+ +Y++I  F++FQL+ ++ A
Sbjct: 804  KADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVA 863

Query: 714  LTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTK 773
            + +      +   +PL A+Q+LW+N+IMD   + +L  EP  + ++ + P      ++++
Sbjct: 864  VIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISR 923

Query: 774  NLILKIL---VSSIIIVCGTLFVFWRELRDNVITPRDT----------TMTFTCFVFFDM 820
             ++  IL   V  + I+   LFV   EL  ++ + R+           T+ F  FV   +
Sbjct: 924  TMMKNILGHAVYQLAIIFTLLFV--GELFFDIDSGRNAPLHSPPSEHYTIIFNTFVMMQL 981

Query: 821  FNALSSRS--QTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDL 878
            FN +++R     ++VF+ G+ SN +FC  VLG+   Q++++ F    K F    LS    
Sbjct: 982  FNEINARKIHGERNVFD-GIFSNPIFCTIVLGTFGIQIVIVQFG--GKPFSCSPLSTEQW 1038

Query: 879  LFLLGLTSSVCIVAEIIKKVERSREKIQK 907
            L+ L +     +  ++I  +  S+ K  K
Sbjct: 1039 LWCLFVGVGELVWGQVIATIPTSQLKCLK 1067


>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
            sapiens]
          Length = 1173

 Score =  300 bits (769), Expect = 3e-81
 Identities = 257/929 (27%), Positives = 431/929 (46%), Gaps = 140/929 (15%)

Query: 102  DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--CVREGKLEHTLARDLVPGD 159
            +  +I ++++ VV V    ++  EK    L   +  E     +R G+L       LV GD
Sbjct: 156  EGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGD 215

Query: 160  TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFM 219
               +  GD +PAD  L +A DL IDESSLTGE+    K     P   +G      +   +
Sbjct: 216  IAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMV 275

Query: 220  GTLVRCGKAKGVV---IGTG---------------------------------------E 237
             T V      G++   +G G                                       +
Sbjct: 276  VTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLK 335

Query: 238  NSEFGEVF----KMMQAEEAPKTPLQKSMDLLGKQLS---FYSFGIIGIIMLVGWLLGKD 290
            ++E GE+     K   A +  K+ LQ  +  L  Q+         I  II+++ +++   
Sbjct: 336  SAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETF 395

Query: 291  ILE------------------MFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIV 332
            ++E                   F I V++ V A+PEGLP+ VT++LA  V +M+K   +V
Sbjct: 396  VVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLV 455

Query: 333  KKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGY--NQFGEVIVDG 390
            + L   ET+G    ICSDKTGTLT N MTV   +  D  + E+        +  +++V  
Sbjct: 456  RHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHA 515

Query: 391  DVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLD------GLQQ 444
              ++  Y   +    + G +           +G  TE AL+   + +  D       + +
Sbjct: 516  ISINSAYTTKILPPEKEGALPRQ--------VGNKTECALLGFVLDLKRDFQPVREQIPE 567

Query: 445  DYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTY-QSKGQTLTLT 503
            D + K  Y F+S +K M+         D     F KGA E ++K CT    S G+     
Sbjct: 568  DKLYKV-YTFNSVRKSMSTVI---RMPDGGFRLFSKGASEILLKKCTNILNSNGELRGFR 623

Query: 504  QQQRD-VYQQEKARMGSAGLRVLALA-----SGPE---------LGQLTFLGLVGIIDPP 548
             + RD + ++    M   GLR + +A     +G E         +G LT + +VGI DP 
Sbjct: 624  PRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPV 683

Query: 549  RTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ--SVSGEEIDA----- 601
            R  V EA+     +G++++M+TGD+  TA AIA++ G+         + G+E +      
Sbjct: 684  RPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNE 743

Query: 602  ---MDVQQLSQIVPKVAVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDGVNDAVALK 653
               ++ ++L ++ PK+ V  R+SP  K  ++K +      +   VVA+TGDG ND  ALK
Sbjct: 744  KGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALK 803

Query: 654  AADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAA 713
             AD+G AMG  GTDV KEA+D+IL DD+F +I+ A+  G+ +Y++I  F++FQL+ ++ A
Sbjct: 804  KADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVA 863

Query: 714  LTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTK 773
            + +      +   +PL A+Q+LW+N+IMD   + +L  EP  + ++ + P      ++++
Sbjct: 864  VIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISR 923

Query: 774  NLILKIL---VSSIIIVCGTLFVFWRELRDNVITPRDT----------TMTFTCFVFFDM 820
             ++  IL   V  + I+   LFV   EL  ++ + R+           T+ F  FV   +
Sbjct: 924  TMMKNILGHAVYQLAIIFTLLFV--GELFFDIDSGRNAPLHSPPSEHYTIIFNTFVMMQL 981

Query: 821  FNALSSRS--QTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDL 878
            FN +++R     ++VF+ G+ SN +FC  VLG+   Q++++ F    K F    LS    
Sbjct: 982  FNEINARKIHGERNVFD-GIFSNPIFCTIVLGTFGIQIVIVQFG--GKPFSCSPLSTEQW 1038

Query: 879  LFLLGLTSSVCIVAEIIKKVERSREKIQK 907
            L+ L +     +  ++I  +  S+ K  K
Sbjct: 1039 LWCLFVGVGELVWGQVIATIPTSQLKCLK 1067


>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sapiens]
          Length = 1198

 Score =  293 bits (751), Expect = 4e-79
 Identities = 247/913 (27%), Positives = 421/913 (46%), Gaps = 124/913 (13%)

Query: 102  DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--CVREGKLEHTLARDLVPGD 159
            +  +I ++++ VV V    ++  EK    L   +  E     VR G++      ++V GD
Sbjct: 153  EGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGD 212

Query: 160  TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFM 219
               +  GD +PAD    +  DL IDESSLTGE+    K     P   +G      +   +
Sbjct: 213  IAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRML 272

Query: 220  GTLVRCGKAKGVV---IGTGENSEFGEVFKMMQAEEAPKTPLQ----------------- 259
             T V      G++   +G G   E  +  K  Q + A    +Q                 
Sbjct: 273  VTAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEMQPLKSAEGGDADDRKKAS 332

Query: 260  ---KSMDLLGKQLSFYSFGI---------IGIIMLV-------------GWL------LG 288
               K   +L  +L+  +  I         I +I+LV              WL        
Sbjct: 333  MHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYV 392

Query: 289  KDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVIC 348
            +  ++ F I V++ V A+PEGLP+ VT++LA  V +M+K   +V+ L   ET+G    IC
Sbjct: 393  QYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAIC 452

Query: 349  SDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGY--NQFGEVIVDGDVVHGFYNPAVSRIVE 406
            SDKTGTLT N MTV   +  D  + E+        +  E++++   ++  Y   +    +
Sbjct: 453  SDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEK 512

Query: 407  AGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLD------GLQQDYIRKAEYPFSSEQKW 460
             G +           +G  TE  L+   + +  D       + ++ + K  Y F+S +K 
Sbjct: 513  EGALPRQ--------VGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKV-YTFNSVRKS 563

Query: 461  MAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTY-QSKGQTLTLTQQQRDVYQQEKAR-MG 518
            M+       +  R    + KGA E V+K C       G+      + RD   ++    M 
Sbjct: 564  MSTVIKLPDESFR---MYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMA 620

Query: 519  SAGLRVLALA-----SGPE---------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGV 564
              GLR + +A     S PE         L +LT + +VGI DP R  V EA+     +G+
Sbjct: 621  CDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGI 680

Query: 565  SIKMITGDSQETAVAIASRLGLYSKTSQ--SVSGEEIDA--------MDVQQLSQIVPKV 614
            +++M+TGD+  TA AIA + G+         + G+E +         ++ +++ +I PK+
Sbjct: 681  TVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKL 740

Query: 615  AVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVC 669
             V  R+SP  K  ++K +      +   VVA+TGDG ND  ALK AD+G AMG  GTDV 
Sbjct: 741  RVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVA 800

Query: 670  KEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPL 729
            KEA+D+IL DD+F +I+ A+  G+ +Y++I  F++FQL+ ++ A+ +      +   +PL
Sbjct: 801  KEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPL 860

Query: 730  NAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKIL---VSSIII 786
             A+Q+LW+N+IMD   + +L  EP  + ++ + P      ++++ ++  IL   V  + +
Sbjct: 861  KAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLAL 920

Query: 787  VCGTLFVFWRELRDNVITPRDT----------TMTFTCFVFFDMFNALSSRS--QTKSVF 834
            +   LFV   E    + + R+           T+ F  FV   +FN +++R     ++VF
Sbjct: 921  IFTLLFV--GEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVF 978

Query: 835  EIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEI 894
            + G+  N +FC  VLG+   Q++++ F    K F    L +   ++ + +     +  ++
Sbjct: 979  D-GIFRNPIFCTIVLGTFAIQIVIVQFG--GKPFSCSPLQLDQWMWCIFIGLGELVWGQV 1035

Query: 895  IKKVERSREKIQK 907
            I  +  SR K  K
Sbjct: 1036 IATIPTSRLKFLK 1048


>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
            sapiens]
          Length = 1170

 Score =  290 bits (743), Expect = 3e-78
 Identities = 253/910 (27%), Positives = 420/910 (46%), Gaps = 156/910 (17%)

Query: 102  DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPE--CHCVREGKLEHTLARDLVPGD 159
            +  +I  +++IVV V    ++  EK    L   +  E     +R G+L      ++V GD
Sbjct: 151  EGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGD 210

Query: 160  TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNG----DLASRSN 215
               +  GD +PAD  L +  DL IDESSLTGE+    K     P   +G    + + R  
Sbjct: 211  IAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMV 270

Query: 216  IAFMGTLVRCG----------------KAKGVVIGTGEN-----SEFGEVFKMM------ 248
            +  +G   + G                K KG   G  EN     ++ G   ++       
Sbjct: 271  VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQE 330

Query: 249  ------QAEEAPKTPLQKSMDLLGKQLSF-YSFGIIGIIMLV------------------ 283
                  + ++A K P ++   L GK        G  G++M                    
Sbjct: 331  GIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVIN 390

Query: 284  --GWLLG------KDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKL 335
               WL        +  ++ F I +++ V A+PEGLP+ VT++LA  V +M+K   +V+ L
Sbjct: 391  RRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL 450

Query: 336  PIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQFG----------E 385
               ET+G    ICSDKTGTLT N MTV        + A + G+ Y Q            +
Sbjct: 451  DACETMGNATAICSDKTGTLTMNRMTV--------VQAYIGGIHYRQIPSPDVFLPKVLD 502

Query: 386  VIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQD 445
            +IV+G  ++  Y   +    + G +           +G  TE AL+       +  L+QD
Sbjct: 503  LIVNGISINSAYTSKILPPEKEGGLPRQ--------VGNKTECALLGF-----VTDLKQD 549

Query: 446  Y--IRKAE--------YPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTY-Q 494
            Y  +R           Y F+S +K M+    +     R    + KGA E +++ C     
Sbjct: 550  YQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFR---MYSKGASEIILRKCNRILD 606

Query: 495  SKGQTLTLTQQQRD-VYQQEKARMGSAGLRVLALA-------------SGPELGQLTFLG 540
             KG+ +    + RD + +     M   GLR + +A                 L +LT + 
Sbjct: 607  RKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILTELTCIA 666

Query: 541  LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ--SVSGEE 598
            +VGI DP R  V +A+     +G++++M+TGD+  TA AIA++ G+ +       + G+E
Sbjct: 667  VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKE 726

Query: 599  IDAM--------DVQQLSQIVPKVAVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDG 645
             + +        + ++L +I PK+ V  R+SP  K  ++K +      ++  VVA+TGDG
Sbjct: 727  FNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDG 786

Query: 646  VNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRF 705
             ND  ALK AD+G AMG  GTDV KEA+D+IL DD+F +I+ A+  G+ +Y++I  F++F
Sbjct: 787  TNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 846

Query: 706  QLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRN 765
            QL+ ++ A+ +      +   +PL A+Q+LW+N+IMD   + +L  EP  + ++++ P  
Sbjct: 847  QLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYG 906

Query: 766  WKDSILTKNLILKIL--------VSSIIIVCGTLFV---FWRELRDNVITPRDTTMTFTC 814
                ++++ ++  IL        V  I++  G  F      R+   +    +  T+ F  
Sbjct: 907  RNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNT 966

Query: 815  FVFFDMFNALSSRS--QTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTES 872
            FV   +FN ++SR     K+VF  G+  N +FC  VLG+ + Q+ ++ F    K F   S
Sbjct: 967  FVLMQLFNEINSRKIHGEKNVFS-GIYRNIIFCSVVLGTFICQIFIVEFG--GKPFSCTS 1023

Query: 873  LSILDLLFLL 882
            LS+   L+ L
Sbjct: 1024 LSLSQWLWCL 1033


>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
            sapiens]
          Length = 1205

 Score =  290 bits (743), Expect = 3e-78
 Identities = 253/910 (27%), Positives = 420/910 (46%), Gaps = 156/910 (17%)

Query: 102  DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPE--CHCVREGKLEHTLARDLVPGD 159
            +  +I  +++IVV V    ++  EK    L   +  E     +R G+L      ++V GD
Sbjct: 151  EGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGD 210

Query: 160  TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNG----DLASRSN 215
               +  GD +PAD  L +  DL IDESSLTGE+    K     P   +G    + + R  
Sbjct: 211  IAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMV 270

Query: 216  IAFMGTLVRCG----------------KAKGVVIGTGEN-----SEFGEVFKMM------ 248
            +  +G   + G                K KG   G  EN     ++ G   ++       
Sbjct: 271  VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQE 330

Query: 249  ------QAEEAPKTPLQKSMDLLGKQLSF-YSFGIIGIIMLV------------------ 283
                  + ++A K P ++   L GK        G  G++M                    
Sbjct: 331  GIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVIN 390

Query: 284  --GWLLG------KDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKL 335
               WL        +  ++ F I +++ V A+PEGLP+ VT++LA  V +M+K   +V+ L
Sbjct: 391  RRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL 450

Query: 336  PIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQFG----------E 385
               ET+G    ICSDKTGTLT N MTV        + A + G+ Y Q            +
Sbjct: 451  DACETMGNATAICSDKTGTLTMNRMTV--------VQAYIGGIHYRQIPSPDVFLPKVLD 502

Query: 386  VIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQD 445
            +IV+G  ++  Y   +    + G +           +G  TE AL+       +  L+QD
Sbjct: 503  LIVNGISINSAYTSKILPPEKEGGLPRQ--------VGNKTECALLGF-----VTDLKQD 549

Query: 446  Y--IRKAE--------YPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTY-Q 494
            Y  +R           Y F+S +K M+    +     R    + KGA E +++ C     
Sbjct: 550  YQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFR---MYSKGASEIILRKCNRILD 606

Query: 495  SKGQTLTLTQQQRD-VYQQEKARMGSAGLRVLALA-------------SGPELGQLTFLG 540
             KG+ +    + RD + +     M   GLR + +A                 L +LT + 
Sbjct: 607  RKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILTELTCIA 666

Query: 541  LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ--SVSGEE 598
            +VGI DP R  V +A+     +G++++M+TGD+  TA AIA++ G+ +       + G+E
Sbjct: 667  VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKE 726

Query: 599  IDAM--------DVQQLSQIVPKVAVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDG 645
             + +        + ++L +I PK+ V  R+SP  K  ++K +      ++  VVA+TGDG
Sbjct: 727  FNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDG 786

Query: 646  VNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRF 705
             ND  ALK AD+G AMG  GTDV KEA+D+IL DD+F +I+ A+  G+ +Y++I  F++F
Sbjct: 787  TNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 846

Query: 706  QLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRN 765
            QL+ ++ A+ +      +   +PL A+Q+LW+N+IMD   + +L  EP  + ++++ P  
Sbjct: 847  QLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYG 906

Query: 766  WKDSILTKNLILKIL--------VSSIIIVCGTLFV---FWRELRDNVITPRDTTMTFTC 814
                ++++ ++  IL        V  I++  G  F      R+   +    +  T+ F  
Sbjct: 907  RNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNT 966

Query: 815  FVFFDMFNALSSRS--QTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTES 872
            FV   +FN ++SR     K+VF  G+  N +FC  VLG+ + Q+ ++ F    K F   S
Sbjct: 967  FVLMQLFNEINSRKIHGEKNVFS-GIYRNIIFCSVVLGTFICQIFIVEFG--GKPFSCTS 1023

Query: 873  LSILDLLFLL 882
            LS+   L+ L
Sbjct: 1024 LSLSQWLWCL 1033


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,294,913
Number of Sequences: 37866
Number of extensions: 1296665
Number of successful extensions: 3579
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 3207
Number of HSP's gapped (non-prelim): 177
length of query: 919
length of database: 18,247,518
effective HSP length: 111
effective length of query: 808
effective length of database: 14,044,392
effective search space: 11347868736
effective search space used: 11347868736
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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