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Search of human proteins with 4826780
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4826780 solute carrier family 12, member 6 isoform b [Homo
sapiens]
(1099 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4826780 solute carrier family 12, member 6 isoform b [Homo sa... 2192 0.0
gi|110224456 solute carrier family 12, member 6 isoform d [Homo ... 2118 0.0
gi|110224454 solute carrier family 12, member 6 isoform c [Homo ... 2118 0.0
gi|110224452 solute carrier family 12, member 6 isoform c [Homo ... 2118 0.0
gi|110224449 solute carrier family 12, member 6 isoform a [Homo ... 2118 0.0
gi|110224458 solute carrier family 12, member 6 isoform e [Homo ... 2088 0.0
gi|4827006 solute carrier family 12, member 4 isoform a [Homo sa... 1674 0.0
gi|225579065 solute carrier family 12, member 4 isoform d [Homo ... 1665 0.0
gi|225579067 solute carrier family 12, member 4 isoform e [Homo ... 1664 0.0
gi|225579061 solute carrier family 12, member 4 isoform b [Homo ... 1657 0.0
gi|225579063 solute carrier family 12, member 4 isoform c [Homo ... 1641 0.0
gi|198041678 solute carrier family 12 (potassium-chloride transp... 1555 0.0
gi|11968148 solute carrier family 12 (potassium-chloride transpo... 1555 0.0
gi|123701900 solute carrier family 12 (potassium/chloride transp... 1512 0.0
gi|186910319 solute carrier family 12, member 3 isoform 3 [Homo ... 239 1e-62
gi|186910317 solute carrier family 12, member 3 isoform 2 [Homo ... 236 1e-61
gi|186910315 solute carrier family 12, member 3 isoform 1 [Homo ... 236 1e-61
gi|4506975 solute carrier family 12 (sodium/potassium/chloride t... 223 1e-57
gi|134254459 sodium potassium chloride cotransporter 2 [Homo sap... 211 2e-54
gi|31881740 solute carrier family 12 (potassium/chloride transpo... 195 2e-49
gi|38569457 solute carrier family 12, member 8 [Homo sapiens] 104 4e-22
gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo s... 47 1e-04
gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo s... 46 2e-04
gi|4507047 solute carrier family 7 (cationic amino acid transpor... 40 0.009
gi|9790235 solute carrier family 7, member 10 [Homo sapiens] 37 0.079
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho... 36 0.18
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo... 36 0.18
gi|181337167 solute carrier family 7 (cationic amino acid transp... 36 0.18
gi|114326550 solute carrier family 7 (cationic amino acid transp... 35 0.30
gi|114326544 solute carrier family 7 (cationic amino acid transp... 35 0.30
>gi|4826780 solute carrier family 12, member 6 isoform b [Homo
sapiens]
Length = 1099
Score = 2192 bits (5681), Expect = 0.0
Identities = 1099/1099 (100%), Positives = 1099/1099 (100%)
Query: 1 MPHFTVTKVEDPEEGAAASISQEPSLADIKARIQDSDEPDLSQNSITGEHSQLLDDGHKK 60
MPHFTVTKVEDPEEGAAASISQEPSLADIKARIQDSDEPDLSQNSITGEHSQLLDDGHKK
Sbjct: 1 MPHFTVTKVEDPEEGAAASISQEPSLADIKARIQDSDEPDLSQNSITGEHSQLLDDGHKK 60
Query: 61 ARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAEN 120
ARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAEN
Sbjct: 61 ARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAEN 120
Query: 121 ITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCT 180
ITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCT
Sbjct: 121 ITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCT 180
Query: 181 MLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIF 240
MLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIF
Sbjct: 181 MLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIF 240
Query: 241 LVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACV 300
LVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACV
Sbjct: 241 LVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACV 300
Query: 301 IVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCN 360
IVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCN
Sbjct: 301 IVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCN 360
Query: 361 SSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGS 420
SSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGS
Sbjct: 361 SSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGS 420
Query: 421 LNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVY 480
LNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVY
Sbjct: 421 LNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVY 480
Query: 481 LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGA 540
LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGA
Sbjct: 481 LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGA 540
Query: 541 PRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFL 600
PRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFL
Sbjct: 541 PRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFL 600
Query: 601 MCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAG 660
MCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAG
Sbjct: 601 MCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAG 660
Query: 661 MIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHV 720
MIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHV
Sbjct: 661 MIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHV 720
Query: 721 KHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVV 780
KHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVV
Sbjct: 721 KHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVV 780
Query: 781 AAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALL 840
AAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALL
Sbjct: 781 AAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALL 840
Query: 841 VAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLED 900
VAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLED
Sbjct: 841 VAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLED 900
Query: 901 NSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTER 960
NSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTER
Sbjct: 901 NSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTER 960
Query: 961 DREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDL 1020
DREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDL
Sbjct: 961 DREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDL 1020
Query: 1021 LNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEG 1080
LNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEG
Sbjct: 1021 LNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEG 1080
Query: 1081 LERVLLVRGGGSEVITIYS 1099
LERVLLVRGGGSEVITIYS
Sbjct: 1081 LERVLLVRGGGSEVITIYS 1099
>gi|110224456 solute carrier family 12, member 6 isoform d [Homo
sapiens]
Length = 1141
Score = 2118 bits (5487), Expect = 0.0
Identities = 1066/1082 (98%), Positives = 1072/1082 (99%), Gaps = 2/1082 (0%)
Query: 18 ASISQEPSLADIKARIQDSDEPDLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEY 77
A+++ +P +D + QD E DLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEY
Sbjct: 62 ATVALDPP-SDRTSHPQDVIE-DLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEY 119
Query: 78 FDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTF 137
FDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTF
Sbjct: 120 FDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTF 179
Query: 138 MGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 197
MGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP
Sbjct: 180 MGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 239
Query: 198 AGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDAL 257
AGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDAL
Sbjct: 240 AGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDAL 299
Query: 258 KESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFA 317
KESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFA
Sbjct: 300 KESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFA 359
Query: 318 PPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNN 377
PPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNN
Sbjct: 360 PPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNN 419
Query: 378 VTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVDITTSFTLL 437
VTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVDITTSFTLL
Sbjct: 420 VTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVDITTSFTLL 479
Query: 438 VGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLR 497
VGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLR
Sbjct: 480 VGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLR 539
Query: 498 DKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLR 557
DKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLR
Sbjct: 540 DKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLR 599
Query: 558 VFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLR 617
VFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLR
Sbjct: 600 VFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLR 659
Query: 618 TPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGD 677
TPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGD
Sbjct: 660 TPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGD 719
Query: 678 GIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKG 737
GIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKG
Sbjct: 720 GIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKG 779
Query: 738 LTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGL 797
LTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGL
Sbjct: 780 LTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGL 839
Query: 798 GGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSE 857
GGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSE
Sbjct: 840 GGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSE 899
Query: 858 GNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLR 917
GNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLR
Sbjct: 900 GNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLR 959
Query: 918 IEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLT 977
IEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLT
Sbjct: 960 IEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLT 1019
Query: 978 SIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAV 1037
SIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAV
Sbjct: 1020 SIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAV 1079
Query: 1038 KLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITI 1097
KLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITI
Sbjct: 1080 KLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITI 1139
Query: 1098 YS 1099
YS
Sbjct: 1140 YS 1141
>gi|110224454 solute carrier family 12, member 6 isoform c [Homo
sapiens]
Length = 1091
Score = 2118 bits (5487), Expect = 0.0
Identities = 1066/1082 (98%), Positives = 1072/1082 (99%), Gaps = 2/1082 (0%)
Query: 18 ASISQEPSLADIKARIQDSDEPDLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEY 77
A+++ +P +D + QD E DLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEY
Sbjct: 12 ATVALDPP-SDRTSHPQDVIE-DLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEY 69
Query: 78 FDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTF 137
FDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTF
Sbjct: 70 FDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTF 129
Query: 138 MGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 197
MGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP
Sbjct: 130 MGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 189
Query: 198 AGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDAL 257
AGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDAL
Sbjct: 190 AGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDAL 249
Query: 258 KESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFA 317
KESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFA
Sbjct: 250 KESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFA 309
Query: 318 PPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNN 377
PPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNN
Sbjct: 310 PPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNN 369
Query: 378 VTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVDITTSFTLL 437
VTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVDITTSFTLL
Sbjct: 370 VTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVDITTSFTLL 429
Query: 438 VGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLR 497
VGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLR
Sbjct: 430 VGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLR 489
Query: 498 DKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLR 557
DKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLR
Sbjct: 490 DKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLR 549
Query: 558 VFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLR 617
VFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLR
Sbjct: 550 VFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLR 609
Query: 618 TPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGD 677
TPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGD
Sbjct: 610 TPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGD 669
Query: 678 GIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKG 737
GIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKG
Sbjct: 670 GIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKG 729
Query: 738 LTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGL 797
LTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGL
Sbjct: 730 LTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGL 789
Query: 798 GGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSE 857
GGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSE
Sbjct: 790 GGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSE 849
Query: 858 GNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLR 917
GNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLR
Sbjct: 850 GNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLR 909
Query: 918 IEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLT 977
IEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLT
Sbjct: 910 IEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLT 969
Query: 978 SIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAV 1037
SIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAV
Sbjct: 970 SIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAV 1029
Query: 1038 KLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITI 1097
KLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITI
Sbjct: 1030 KLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITI 1089
Query: 1098 YS 1099
YS
Sbjct: 1090 YS 1091
>gi|110224452 solute carrier family 12, member 6 isoform c [Homo
sapiens]
Length = 1091
Score = 2118 bits (5487), Expect = 0.0
Identities = 1066/1082 (98%), Positives = 1072/1082 (99%), Gaps = 2/1082 (0%)
Query: 18 ASISQEPSLADIKARIQDSDEPDLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEY 77
A+++ +P +D + QD E DLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEY
Sbjct: 12 ATVALDPP-SDRTSHPQDVIE-DLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEY 69
Query: 78 FDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTF 137
FDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTF
Sbjct: 70 FDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTF 129
Query: 138 MGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 197
MGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP
Sbjct: 130 MGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 189
Query: 198 AGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDAL 257
AGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDAL
Sbjct: 190 AGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDAL 249
Query: 258 KESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFA 317
KESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFA
Sbjct: 250 KESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFA 309
Query: 318 PPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNN 377
PPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNN
Sbjct: 310 PPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNN 369
Query: 378 VTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVDITTSFTLL 437
VTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVDITTSFTLL
Sbjct: 370 VTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVDITTSFTLL 429
Query: 438 VGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLR 497
VGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLR
Sbjct: 430 VGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLR 489
Query: 498 DKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLR 557
DKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLR
Sbjct: 490 DKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLR 549
Query: 558 VFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLR 617
VFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLR
Sbjct: 550 VFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLR 609
Query: 618 TPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGD 677
TPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGD
Sbjct: 610 TPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGD 669
Query: 678 GIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKG 737
GIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKG
Sbjct: 670 GIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKG 729
Query: 738 LTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGL 797
LTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGL
Sbjct: 730 LTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGL 789
Query: 798 GGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSE 857
GGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSE
Sbjct: 790 GGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSE 849
Query: 858 GNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLR 917
GNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLR
Sbjct: 850 GNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLR 909
Query: 918 IEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLT 977
IEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLT
Sbjct: 910 IEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLT 969
Query: 978 SIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAV 1037
SIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAV
Sbjct: 970 SIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAV 1029
Query: 1038 KLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITI 1097
KLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITI
Sbjct: 1030 KLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITI 1089
Query: 1098 YS 1099
YS
Sbjct: 1090 YS 1091
>gi|110224449 solute carrier family 12, member 6 isoform a [Homo
sapiens]
Length = 1150
Score = 2118 bits (5487), Expect = 0.0
Identities = 1066/1082 (98%), Positives = 1072/1082 (99%), Gaps = 2/1082 (0%)
Query: 18 ASISQEPSLADIKARIQDSDEPDLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEY 77
A+++ +P +D + QD E DLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEY
Sbjct: 71 ATVALDPP-SDRTSHPQDVIE-DLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEY 128
Query: 78 FDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTF 137
FDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTF
Sbjct: 129 FDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTF 188
Query: 138 MGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 197
MGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP
Sbjct: 189 MGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVP 248
Query: 198 AGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDAL 257
AGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDAL
Sbjct: 249 AGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDAL 308
Query: 258 KESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFA 317
KESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFA
Sbjct: 309 KESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFA 368
Query: 318 PPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNN 377
PPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNN
Sbjct: 369 PPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNN 428
Query: 378 VTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVDITTSFTLL 437
VTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVDITTSFTLL
Sbjct: 429 VTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVDITTSFTLL 488
Query: 438 VGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLR 497
VGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLR
Sbjct: 489 VGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLR 548
Query: 498 DKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLR 557
DKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLR
Sbjct: 549 DKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLR 608
Query: 558 VFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLR 617
VFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLR
Sbjct: 609 VFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLR 668
Query: 618 TPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGD 677
TPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGD
Sbjct: 669 TPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGD 728
Query: 678 GIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKG 737
GIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKG
Sbjct: 729 GIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKG 788
Query: 738 LTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGL 797
LTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGL
Sbjct: 789 LTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGL 848
Query: 798 GGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSE 857
GGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSE
Sbjct: 849 GGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSE 908
Query: 858 GNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLR 917
GNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLR
Sbjct: 909 GNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLR 968
Query: 918 IEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLT 977
IEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLT
Sbjct: 969 IEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLT 1028
Query: 978 SIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAV 1037
SIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAV
Sbjct: 1029 SIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAV 1088
Query: 1038 KLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITI 1097
KLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITI
Sbjct: 1089 KLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITI 1148
Query: 1098 YS 1099
YS
Sbjct: 1149 YS 1150
>gi|110224458 solute carrier family 12, member 6 isoform e [Homo
sapiens]
Length = 1135
Score = 2088 bits (5410), Expect = 0.0
Identities = 1045/1045 (100%), Positives = 1045/1045 (100%)
Query: 55 DDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKE 114
DDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKE
Sbjct: 91 DDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKE 150
Query: 115 HEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVL 174
HEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVL
Sbjct: 151 HEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVL 210
Query: 175 ICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYIL 234
ICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYIL
Sbjct: 211 ICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYIL 270
Query: 235 GAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFAS 294
GAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFAS
Sbjct: 271 GAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFAS 330
Query: 295 LFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKL 354
LFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKL
Sbjct: 331 LFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKL 390
Query: 355 WGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKS 414
WGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKS
Sbjct: 391 WGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKS 450
Query: 415 SDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAIL 474
SDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAIL
Sbjct: 451 SDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAIL 510
Query: 475 TTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGL 534
TTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGL
Sbjct: 511 TTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGL 570
Query: 535 QSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPI 594
QSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPI
Sbjct: 571 QSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPI 630
Query: 595 LSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIV 654
LSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIV
Sbjct: 631 LSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIV 690
Query: 655 AMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKL 714
AMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKL
Sbjct: 691 AMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKL 750
Query: 715 DEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKG 774
DEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKG
Sbjct: 751 DEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKG 810
Query: 775 FCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTA 834
FCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTA
Sbjct: 811 FCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTA 870
Query: 835 AHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFT 894
AHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFT
Sbjct: 871 AHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFT 930
Query: 895 VAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMR 954
VAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMR
Sbjct: 931 VAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMR 990
Query: 955 LSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSM 1014
LSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSM
Sbjct: 991 LSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSM 1050
Query: 1015 EGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFL 1074
EGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFL
Sbjct: 1051 EGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFL 1110
Query: 1075 EVLTEGLERVLLVRGGGSEVITIYS 1099
EVLTEGLERVLLVRGGGSEVITIYS
Sbjct: 1111 EVLTEGLERVLLVRGGGSEVITIYS 1135
>gi|4827006 solute carrier family 12, member 4 isoform a [Homo
sapiens]
Length = 1085
Score = 1674 bits (4335), Expect = 0.0
Identities = 838/1105 (75%), Positives = 944/1105 (85%), Gaps = 26/1105 (2%)
Query: 1 MPHFTVTKVEDPEEGAAASISQEPSLADIKARIQDSDEPDLSQNSITGEHSQLLD-DGHK 59
MPHFTV V+ P G D D + GE ++L D DGH
Sbjct: 1 MPHFTVVPVDGPRRG-------------------DYDNLEGLSWVDYGERAELDDSDGHG 41
Query: 60 KARNA--YLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEE 117
R + +L+ G +Y+D+NLALFEEE+D RPKVSSLL ++ +YTNLTQGAKEHEE
Sbjct: 42 NHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEE 101
Query: 118 AENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICC 177
AE+ +++ + P MGT MGVYLPCLQNIFGVILFLRLTW+VGTAGVLQA IVLICC
Sbjct: 102 AESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICC 161
Query: 178 CCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAI 237
CCT+LTAISMSAIATNGVVPAGGSYFMISR+LGPEFGGAVGLCFYLGTTFAAAMYILGAI
Sbjct: 162 CCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAI 221
Query: 238 EIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFL 297
EI L YI P AAIF+ A S A LNNMRVYGT FL M LVVF+GV+YVNKFASLFL
Sbjct: 222 EILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLFL 281
Query: 298 ACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGF 357
ACVI+SIL+IYAG IKS F PP FPVCMLGNRTLS D+C+KT ++N TV ++LW F
Sbjct: 282 ACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQLWSF 341
Query: 358 FCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEK---PSAKS 414
FC+S +CD YF+ NNVT I GIPG A+G++ ENLWS YL KG+I+EK PSA +
Sbjct: 342 FCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLPSADA 401
Query: 415 SDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAIL 474
+ SL YV+ DI TSFT+LVGIFFPSVTGIMAGSNRSGDL+DAQKSIP+GTILAI+
Sbjct: 402 PSLKESLPL-YVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAII 460
Query: 475 TTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGL 534
TTS VY S+VVLFGACIEGVVLRDK+GD V NLVVGTL+WPSPWVIVIGSFFSTCGAGL
Sbjct: 461 TTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAGL 520
Query: 535 QSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPI 594
QSLTGAPRLLQAIAKDNIIPFLRVFGH K NGEPTWALLLTA IAELGILIASLD+VAPI
Sbjct: 521 QSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLDMVAPI 580
Query: 595 LSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIV 654
LSMFFLMCYLFVNLACA+QTLLRTPNWRPRF+YYHWALSF+GMS+CLALMF+SSWYYA+V
Sbjct: 581 LSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALV 640
Query: 655 AMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKL 714
AM+IAGMIYKYIEYQGAEKEWGDGIRGLSLSAAR+ALLRLEEGPPHTKNWRPQLLVLLKL
Sbjct: 641 AMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLLKL 700
Query: 715 DEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKG 774
DEDLHVK+PRLLTFASQLKAGKGLTIVGSVI G+FLE+YGEA AAEQTIK++ME EKVKG
Sbjct: 701 DEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIEKVKG 760
Query: 775 FCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTA 834
FCQ+VVA+K+REG++HLIQSCGLGGM+HN+VV+GWP GWRQSED RAWKTFI TVR TTA
Sbjct: 761 FCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCTTA 820
Query: 835 AHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFT 894
AHLALLV KNI+F+PSN E++ EG+IDVWWIVHDGGMLMLLPFLL+QHKVWRKC +RIFT
Sbjct: 821 AHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIFT 880
Query: 895 VAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMR 954
VAQ++DNSIQMKKDLA FLYHLR+EAEVEVVEMH+SDISAYTYERTLMMEQRSQMLR MR
Sbjct: 881 VAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQMLRQMR 940
Query: 955 LSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSM 1014
L+KTER+REAQLVKDR+S LRL S+ SDE++E+ +K+ MTWT+DKYM + +
Sbjct: 941 LTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTWTRDKYMTETWDPSHAP 1000
Query: 1015 EGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFL 1074
+ F++L++++PDQSNVRRMHTAVKLNEVIV +SH+A+LVLLNMPGPPRN EGDENYMEFL
Sbjct: 1001 DNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENYMEFL 1060
Query: 1075 EVLTEGLERVLLVRGGGSEVITIYS 1099
EVLTEGLERVLLVRGGG EVITIYS
Sbjct: 1061 EVLTEGLERVLLVRGGGREVITIYS 1085
>gi|225579065 solute carrier family 12, member 4 isoform d [Homo
sapiens]
Length = 1079
Score = 1665 bits (4312), Expect = 0.0
Identities = 821/1049 (78%), Positives = 925/1049 (88%), Gaps = 4/1049 (0%)
Query: 54 LDDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAK 113
L G+ + + +L+ G +Y+D+NLALFEEE+D RPKVSSLL ++ +YTNLTQGAK
Sbjct: 32 LGHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAK 91
Query: 114 EHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIV 173
EHEEAE+ +++ + P MGT MGVYLPCLQNIFGVILFLRLTW+VGTAGVLQA IV
Sbjct: 92 EHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIV 151
Query: 174 LICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYI 233
LICCCCT+LTAISMSAIATNGVVPAGGSYFMISR+LGPEFGGAVGLCFYLGTTFAAAMYI
Sbjct: 152 LICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYI 211
Query: 234 LGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFA 293
LGAIEI L YI P AAIF+ A S A LNNMRVYGT FL M LVVF+GV+YVNKFA
Sbjct: 212 LGAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFA 271
Query: 294 SLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSK 353
SLFLACVI+SIL+IYAG IKS F PP FPVCMLGNRTLS D+C+KT ++N TV ++
Sbjct: 272 SLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQ 331
Query: 354 LWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEK---P 410
LW FFC+S +CD YF+ NNVT I GIPG A+G++ ENLWS YL KG+I+EK P
Sbjct: 332 LWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLP 391
Query: 411 SAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTI 470
SA + + SL YV+ DI TSFT+LVGIFFPSVTGIMAGSNRSGDL+DAQKSIP+GTI
Sbjct: 392 SADAPSLKESLPL-YVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTI 450
Query: 471 LAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTC 530
LAI+TTS VY S+VVLFGACIEGVVLRDK+GD V NLVVGTL+WPSPWVIVIGSFFSTC
Sbjct: 451 LAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTC 510
Query: 531 GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDL 590
GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH K NGEPTWALLLTA IAELGILIASLD+
Sbjct: 511 GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLDM 570
Query: 591 VAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWY 650
VAPILSMFFLMCYLFVNLACA+QTLLRTPNWRPRF+YYHWALSF+GMS+CLALMF+SSWY
Sbjct: 571 VAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWY 630
Query: 651 YAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLV 710
YA+VAM+IAGMIYKYIEYQGAEKEWGDGIRGLSLSAAR+ALLRLEEGPPHTKNWRPQLLV
Sbjct: 631 YALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLV 690
Query: 711 LLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAE 770
LLKLDEDLHVK+PRLLTFASQLKAGKGLTIVGSVI G+FLE+YGEA AAEQTIK++ME E
Sbjct: 691 LLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIE 750
Query: 771 KVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVR 830
KVKGFCQ+VVA+K+REG++HLIQSCGLGGM+HN+VV+GWP GWRQSED RAWKTFI TVR
Sbjct: 751 KVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVR 810
Query: 831 VTTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSI 890
TTAAHLALLV KNI+F+PSN E++ EG+IDVWWIVHDGGMLMLLPFLL+QHKVWRKC +
Sbjct: 811 CTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRM 870
Query: 891 RIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQML 950
RIFTVAQ++DNSIQMKKDLA FLYHLR+EAEVEVVEMH+SDISAYTYERTLMMEQRSQML
Sbjct: 871 RIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQML 930
Query: 951 RHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQK 1010
R MRL+KTER+REAQLVKDR+S LRL S+ SDE++E+ +K+ MTWT+DKYM
Sbjct: 931 RQMRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTWTRDKYMTETWDP 990
Query: 1011 AKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENY 1070
+ + + F++L++++PDQSNVRRMHTAVKLNEVIV +SH+A+LVLLNMPGPPRN EGDENY
Sbjct: 991 SHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENY 1050
Query: 1071 MEFLEVLTEGLERVLLVRGGGSEVITIYS 1099
MEFLEVLTEGLERVLLVRGGG EVITIYS
Sbjct: 1051 MEFLEVLTEGLERVLLVRGGGREVITIYS 1079
>gi|225579067 solute carrier family 12, member 4 isoform e [Homo
sapiens]
Length = 1054
Score = 1664 bits (4310), Expect = 0.0
Identities = 820/1046 (78%), Positives = 924/1046 (88%), Gaps = 4/1046 (0%)
Query: 57 GHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHE 116
G+ + + +L+ G +Y+D+NLALFEEE+D RPKVSSLL ++ +YTNLTQGAKEHE
Sbjct: 10 GNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHE 69
Query: 117 EAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLIC 176
EAE+ +++ + P MGT MGVYLPCLQNIFGVILFLRLTW+VGTAGVLQA IVLIC
Sbjct: 70 EAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLIC 129
Query: 177 CCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGA 236
CCCT+LTAISMSAIATNGVVPAGGSYFMISR+LGPEFGGAVGLCFYLGTTFAAAMYILGA
Sbjct: 130 CCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGA 189
Query: 237 IEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLF 296
IEI L YI P AAIF+ A S A LNNMRVYGT FL M LVVF+GV+YVNKFASLF
Sbjct: 190 IEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLF 249
Query: 297 LACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWG 356
LACVI+SIL+IYAG IKS F PP FPVCMLGNRTLS D+C+KT ++N TV ++LW
Sbjct: 250 LACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQLWS 309
Query: 357 FFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEK---PSAK 413
FFC+S +CD YF+ NNVT I GIPG A+G++ ENLWS YL KG+I+EK PSA
Sbjct: 310 FFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLPSAD 369
Query: 414 SSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAI 473
+ + SL YV+ DI TSFT+LVGIFFPSVTGIMAGSNRSGDL+DAQKSIP+GTILAI
Sbjct: 370 APSLKESLPL-YVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAI 428
Query: 474 LTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAG 533
+TTS VY S+VVLFGACIEGVVLRDK+GD V NLVVGTL+WPSPWVIVIGSFFSTCGAG
Sbjct: 429 ITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAG 488
Query: 534 LQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAP 593
LQSLTGAPRLLQAIAKDNIIPFLRVFGH K NGEPTWALLLTA IAELGILIASLD+VAP
Sbjct: 489 LQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLDMVAP 548
Query: 594 ILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAI 653
ILSMFFLMCYLFVNLACA+QTLLRTPNWRPRF+YYHWALSF+GMS+CLALMF+SSWYYA+
Sbjct: 549 ILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYAL 608
Query: 654 VAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLK 713
VAM+IAGMIYKYIEYQGAEKEWGDGIRGLSLSAAR+ALLRLEEGPPHTKNWRPQLLVLLK
Sbjct: 609 VAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLLK 668
Query: 714 LDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVK 773
LDEDLHVK+PRLLTFASQLKAGKGLTIVGSVI G+FLE+YGEA AAEQTIK++ME EKVK
Sbjct: 669 LDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIEKVK 728
Query: 774 GFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTT 833
GFCQ+VVA+K+REG++HLIQSCGLGGM+HN+VV+GWP GWRQSED RAWKTFI TVR TT
Sbjct: 729 GFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCTT 788
Query: 834 AAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIF 893
AAHLALLV KNI+F+PSN E++ EG+IDVWWIVHDGGMLMLLPFLL+QHKVWRKC +RIF
Sbjct: 789 AAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIF 848
Query: 894 TVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHM 953
TVAQ++DNSIQMKKDLA FLYHLR+EAEVEVVEMH+SDISAYTYERTLMMEQRSQMLR M
Sbjct: 849 TVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQMLRQM 908
Query: 954 RLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKS 1013
RL+KTER+REAQLVKDR+S LRL S+ SDE++E+ +K+ MTWT+DKYM + +
Sbjct: 909 RLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTWTRDKYMTETWDPSHA 968
Query: 1014 MEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEF 1073
+ F++L++++PDQSNVRRMHTAVKLNEVIV +SH+A+LVLLNMPGPPRN EGDENYMEF
Sbjct: 969 PDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENYMEF 1028
Query: 1074 LEVLTEGLERVLLVRGGGSEVITIYS 1099
LEVLTEGLERVLLVRGGG EVITIYS
Sbjct: 1029 LEVLTEGLERVLLVRGGGREVITIYS 1054
>gi|225579061 solute carrier family 12, member 4 isoform b [Homo
sapiens]
Length = 1079
Score = 1657 bits (4291), Expect = 0.0
Identities = 832/1105 (75%), Positives = 938/1105 (84%), Gaps = 32/1105 (2%)
Query: 1 MPHFTVTKVEDPEEGAAASISQEPSLADIKARIQDSDEPDLSQNSITGEHSQLLD-DGHK 59
MPHFTV V+ P G D D + GE ++L D DGH
Sbjct: 1 MPHFTVVPVDGPRRG-------------------DYDNLEGLSWVDYGERAELDDSDGHG 41
Query: 60 KARNA--YLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEE 117
R + +L+ G +Y+D+NLALFEEE+D RPKVSSLL ++ +YTNLTQGAKEHEE
Sbjct: 42 NHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEE 101
Query: 118 AENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICC 177
AE+ +++ + P MGT MGVYLPCLQNIFGVILFLRLTW+VGTAGVLQA IVLICC
Sbjct: 102 AESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICC 161
Query: 178 CCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAI 237
CCT+LTAISMSAIATNGVVPAGGSYFMISR+LGPEFGGAVGLCFYLGTTFAAAMYILGAI
Sbjct: 162 CCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAI 221
Query: 238 EIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFL 297
EI L YI P AAIF+ A S A LNNMRVYGT FL M LVVF+GV+YVNKFASLFL
Sbjct: 222 EILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLFL 281
Query: 298 ACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGF 357
ACVI+SIL+IYAG IKS F PP FPVCMLGNRTLS D+C+KT ++N TV ++LW F
Sbjct: 282 ACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQLWSF 341
Query: 358 FCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEK---PSAKS 414
FC+S +CD YF+ NNVT I GIPG A+G++ ENLWS YL KG+I+EK PSA +
Sbjct: 342 FCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLPSADA 401
Query: 415 SDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAIL 474
+ SL YV+ DI TSFT+LVGIFFPSVTGIMAGSNRSGDL+DAQKSIP+GTILAI+
Sbjct: 402 PSLKESLPL-YVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAII 460
Query: 475 TTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGL 534
TTS VY S+VVLFGACIEGVVLRDK+GD V NLVVGTL+WPSPWVIVIGSFFSTCGAGL
Sbjct: 461 TTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAGL 520
Query: 535 QSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPI 594
QSLTGAPRLLQAIAKDNIIPFLRVFGH K NGEPTWALLLTA IAELGILIASLD+VAPI
Sbjct: 521 QSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLDMVAPI 580
Query: 595 LSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIV 654
LSMFFLMCYLFVNLACA+QTLLRTPNWRPRF+YYHWALSF+GMS+CLALMF+SSWYYA+V
Sbjct: 581 LSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALV 640
Query: 655 AMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKL 714
AM+IAGMIYKYIEYQGAEKEWGDGIRGLSLSAAR+ALLRLEEGPPHTKNWRPQLLVLLKL
Sbjct: 641 AMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLLKL 700
Query: 715 DEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKG 774
DEDLHVK+PRLLTFASQLKAGKGLTIVGSVI G+FLE+YGEA AAEQTIK++ME EKVKG
Sbjct: 701 DEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIEKVKG 760
Query: 775 FCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTA 834
FCQ+VVA+K+REG++HLIQSCGLGGM+HN+VV+GWP GWRQSED RAWKTFI TVR TTA
Sbjct: 761 FCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCTTA 820
Query: 835 AHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFT 894
AHLALLV KNI+F+PSN E++ EG+IDVWWIVHDGGMLMLLPFLL+QHKVWRKC +RIFT
Sbjct: 821 AHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIFT 880
Query: 895 VAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMR 954
VAQ++DNSIQMKKDLA FLYHLR+EAE H+SDISAYTYERTLMMEQRSQMLR MR
Sbjct: 881 VAQMDDNSIQMKKDLAVFLYHLRLEAE------HNSDISAYTYERTLMMEQRSQMLRQMR 934
Query: 955 LSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSM 1014
L+KTER+REAQLVKDR+S LRL S+ SDE++E+ +K+ MTWT+DKYM + +
Sbjct: 935 LTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTWTRDKYMTETWDPSHAP 994
Query: 1015 EGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFL 1074
+ F++L++++PDQSNVRRMHTAVKLNEVIV +SH+A+LVLLNMPGPPRN EGDENYMEFL
Sbjct: 995 DNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENYMEFL 1054
Query: 1075 EVLTEGLERVLLVRGGGSEVITIYS 1099
EVLTEGLERVLLVRGGG EVITIYS
Sbjct: 1055 EVLTEGLERVLLVRGGGREVITIYS 1079
>gi|225579063 solute carrier family 12, member 4 isoform c [Homo
sapiens]
Length = 1087
Score = 1641 bits (4250), Expect = 0.0
Identities = 809/1016 (79%), Positives = 905/1016 (89%), Gaps = 4/1016 (0%)
Query: 87 EEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQ 146
EE+D RPKVSSLL ++ +YTNLTQGAKEHEEAE+ +++ + P MGT MGVYLPCLQ
Sbjct: 73 EELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQ 132
Query: 147 NIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMIS 206
NIFGVILFLRLTW+VGTAGVLQA IVLICCCCT+LTAISMSAIATNGVVPAGGSYFMIS
Sbjct: 133 NIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMIS 192
Query: 207 RALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDALKESAAMLNN 266
R+LGPEFGGAVGLCFYLGTTFAAAMYILGAIEI L YI P AAIF+ A S A LNN
Sbjct: 193 RSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSNATLNN 252
Query: 267 MRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPVCML 326
MRVYGT FL M LVVF+GV+YVNKFASLFLACVI+SIL+IYAG IKS F PP FPVCML
Sbjct: 253 MRVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCML 312
Query: 327 GNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPG 386
GNRTLS D+C+KT ++N TV ++LW FFC+S +CD YF+ NNVT I GIPG
Sbjct: 313 GNRTLSRDQFDICAKTAVVDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPG 372
Query: 387 LASGIITENLWSNYLPKGEIIEK---PSAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFP 443
A+G++ ENLWS YL KG+I+EK PSA + + SL YV+ DI TSFT+LVGIFFP
Sbjct: 373 AAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKESLPL-YVVADIATSFTVLVGIFFP 431
Query: 444 SVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDA 503
SVTGIMAGSNRSGDL+DAQKSIP+GTILAI+TTS VY S+VVLFGACIEGVVLRDK+GD
Sbjct: 432 SVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKYGDG 491
Query: 504 VKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSK 563
V NLVVGTL+WPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGH K
Sbjct: 492 VSRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGK 551
Query: 564 ANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRP 623
NGEPTWALLLTA IAELGILIASLD+VAPILSMFFLMCYLFVNLACA+QTLLRTPNWRP
Sbjct: 552 VNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRP 611
Query: 624 RFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLS 683
RF+YYHWALSF+GMS+CLALMF+SSWYYA+VAM+IAGMIYKYIEYQGAEKEWGDGIRGLS
Sbjct: 612 RFKYYHWALSFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLS 671
Query: 684 LSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGS 743
LSAAR+ALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVK+PRLLTFASQLKAGKGLTIVGS
Sbjct: 672 LSAARYALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGS 731
Query: 744 VIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHN 803
VI G+FLE+YGEA AAEQTIK++ME EKVKGFCQ+VVA+K+REG++HLIQSCGLGGM+HN
Sbjct: 732 VIQGSFLESYGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHN 791
Query: 804 TVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSEGNIDVW 863
+VV+GWP GWRQSED RAWKTFI TVR TTAAHLALLV KNI+F+PSN E++ EG+IDVW
Sbjct: 792 SVVLGWPYGWRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLEGHIDVW 851
Query: 864 WIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVE 923
WIVHDGGMLMLLPFLL+QHKVWRKC +RIFTVAQ++DNSIQMKKDLA FLYHLR+EAEVE
Sbjct: 852 WIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVE 911
Query: 924 VVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDE 983
VVEMH+SDISAYTYERTLMMEQRSQMLR MRL+KTER+REAQLVKDR+S LRL S+ SDE
Sbjct: 912 VVEMHNSDISAYTYERTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLESLYSDE 971
Query: 984 DEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVI 1043
++E+ +K+ MTWT+DKYM + + + F++L++++PDQSNVRRMHTAVKLNEVI
Sbjct: 972 EDESAVGADKIQMTWTRDKYMTETWDPSHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVI 1031
Query: 1044 VNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITIYS 1099
V +SH+A+LVLLNMPGPPRN EGDENYMEFLEVLTEGLERVLLVRGGG EVITIYS
Sbjct: 1032 VTRSHDARLVLLNMPGPPRNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS 1087
>gi|198041678 solute carrier family 12 (potassium-chloride
transporter), member 5 isoform 1 [Homo sapiens]
Length = 1139
Score = 1555 bits (4026), Expect = 0.0
Identities = 778/1123 (69%), Positives = 906/1123 (80%), Gaps = 60/1123 (5%)
Query: 36 SDEPDLSQNSITGEH----SQLLDDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDT 91
S +P+ ++S+ + DG+ K + ++N+++ E+G EY KN+ALFEEEMDT
Sbjct: 18 SPDPESRRHSVADPRHLPGEDVKGDGNPKESSPFINSTDTEKGKEYDGKNMALFEEEMDT 77
Query: 92 RPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGV 151
P VSSLL+ +ANYTNL QG++EHEEAEN GKKKP + P+MGTFMGVYLPCLQNIFGV
Sbjct: 78 SPMVSSLLSGLANYTNLPQGSREHEEAENNEGGKKKPVQAPRMGTFMGVYLPCLQNIFGV 137
Query: 152 ILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGP 211
ILFLRLTWVVG AG++++F +V ICC CTMLTAISMSAIATNGVVPAGGSY+MISR+LGP
Sbjct: 138 ILFLRLTWVVGIAGIMESFCMVFICCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGP 197
Query: 212 EFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYG 271
EFGGAVGLCFYLGTTFA AMYILG IEI L Y+ P AIF ++DA E+AAMLNNMRVYG
Sbjct: 198 EFGGAVGLCFYLGTTFAGAMYILGTIEILLAYLFPAMAIFKAEDASGEAAAMLNNMRVYG 257
Query: 272 TAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTL 331
T L M VVF+GV+YVNKFA +FL CVI+SILAIYAG IKS+F PP+FP+C+LGNRTL
Sbjct: 258 TCVLTCMATVVFVGVKYVNKFALVFLGCVILSILAIYAGVIKSAFDPPNFPICLLGNRTL 317
Query: 332 SSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGI 391
S DVC+K N TV ++LWG FC SS+F NATCDEYF NNVT IQGIPG ASG+
Sbjct: 318 SRHGFDVCAKLAWEGNETVTTRLWGLFC-SSRFLNATCDEYFTRNNVTEIQGIPGAASGL 376
Query: 392 ITENLWSNYLPKGEIIEKPSAKSSDVLGS----LNHEYVLVDITTSFTLLVGIFFPSVTG 447
I ENLWS+YL KG I+E+ S + ++H YV D+T+ FTLLVGI+FPSVTG
Sbjct: 377 IKENLWSSYLTKGVIVERSGMTSVGLADGTPIDMDHPYVFSDMTSYFTLLVGIYFPSVTG 436
Query: 448 IMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGN 507
IMAGSNRSGDL+DAQKSIP GTILAI TTS VY+S+VVLFGACIEGVVLRDKFG+AV GN
Sbjct: 437 IMAGSNRSGDLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGN 496
Query: 508 LVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGE 567
LVVGTL+WPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAI++D I+PFL+VFGH KANGE
Sbjct: 497 LVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGE 556
Query: 568 PTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRY 627
PTWALLLTA I E+GILIASLD VAPILSMFFLMCY+FVNLACA+QTLLRTPNWRPRFRY
Sbjct: 557 PTWALLLTACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRY 616
Query: 628 YHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAA 687
YHW LSF+GMS+CLALMFI SWYYA+VAM+IAG+IYKYIEY+GAEKEWGDGIRGLSLSAA
Sbjct: 617 YHWTLSFLGMSLCLALMFICSWYYALVAMLIAGLIYKYIEYRGAEKEWGDGIRGLSLSAA 676
Query: 688 RFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVG 747
R+ALLRLEEGPPHTKNWRPQLLVL+++D+D +V HP+LL+ SQLKAGKGLTIVGSV+ G
Sbjct: 677 RYALLRLEEGPPHTKNWRPQLLVLVRVDQDQNVVHPQLLSLTSQLKAGKGLTIVGSVLEG 736
Query: 748 NFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVM 807
FLEN+ +A AE++I+ LMEAEKVKGFCQ+V+++ LR+G+SHLIQS GLGG++HNTV++
Sbjct: 737 TFLENHPQAQRAEESIRRLMEAEKVKGFCQVVISSNLRDGVSHLIQSGGLGGLQHNTVLV 796
Query: 808 GWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVH 867
GWP WRQ ED + W+ FI VR TTA HLALLV KN+S FP N E+FSEG+IDVWWIVH
Sbjct: 797 GWPRNWRQKEDHQTWRNFIELVRETTAGHLALLVTKNVSMFPGNPERFSEGSIDVWWIVH 856
Query: 868 DGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEM 927
DGGMLMLLPFLL+ HKVWRKC +RIFTVAQ++DNSIQMKKDL TFLYHLRI AEVEVVEM
Sbjct: 857 DGGMLMLLPFLLRHHKVWRKCKMRIFTVAQMDDNSIQMKKDLTTFLYHLRITAEVEVVEM 916
Query: 928 HDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDR-----------NSMLRL 976
H+SDISAYTYE+TL+MEQRSQ+L+ M L+K ER+RE Q + D N+ LRL
Sbjct: 917 HESDISAYTYEKTLVMEQRSQILKQMHLTKNEREREIQSITDESRGSIRRKNPANTRLRL 976
Query: 977 T---------------------------------SIGSDEDEETETYQEKVHMTWTKDKY 1003
S G + + E ET EKVH+TWTKDK
Sbjct: 977 NVPEETAGDSEEKPEEEVQLIHDQSAPSCPSSSPSPGEEPEGEGETDPEKVHLTWTKDKS 1036
Query: 1004 MA--SRGQKAKSMEGFQDLLNMRPD-----QSNVRRMHTAVKLNEVIVNKSHEAKLVLLN 1056
+A ++G S EG +D +M+P+ QSNVRRMHTAV+LNEVIV KS +AKLVLLN
Sbjct: 1037 VAEKNKGPSPVSSEGIKDFFSMKPEWENLNQSNVRRMHTAVRLNEVIVKKSRDAKLVLLN 1096
Query: 1057 MPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITIYS 1099
MPGPPRN GDENYMEFLEVLTE L+RV+LVRGGG EVITIYS
Sbjct: 1097 MPGPPRNRNGDENYMEFLEVLTEHLDRVMLVRGGGREVITIYS 1139
>gi|11968148 solute carrier family 12 (potassium-chloride
transporter), member 5 isoform 2 [Homo sapiens]
Length = 1116
Score = 1555 bits (4025), Expect = 0.0
Identities = 775/1099 (70%), Positives = 897/1099 (81%), Gaps = 56/1099 (5%)
Query: 56 DGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEH 115
DG+ K + ++N+++ E+G EY KN+ALFEEEMDT P VSSLL+ +ANYTNL QG++EH
Sbjct: 19 DGNPKESSPFINSTDTEKGKEYDGKNMALFEEEMDTSPMVSSLLSGLANYTNLPQGSREH 78
Query: 116 EEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLI 175
EEAEN GKKKP + P+MGTFMGVYLPCLQNIFGVILFLRLTWVVG AG++++F +V I
Sbjct: 79 EEAENNEGGKKKPVQAPRMGTFMGVYLPCLQNIFGVILFLRLTWVVGIAGIMESFCMVFI 138
Query: 176 CCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILG 235
CC CTMLTAISMSAIATNGVVPAGGSY+MISR+LGPEFGGAVGLCFYLGTTFA AMYILG
Sbjct: 139 CCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILG 198
Query: 236 AIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASL 295
IEI L Y+ P AIF ++DA E+AAMLNNMRVYGT L M VVF+GV+YVNKFA +
Sbjct: 199 TIEILLAYLFPAMAIFKAEDASGEAAAMLNNMRVYGTCVLTCMATVVFVGVKYVNKFALV 258
Query: 296 FLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLW 355
FL CVI+SILAIYAG IKS+F PP+FP+C+LGNRTLS DVC+K N TV ++LW
Sbjct: 259 FLGCVILSILAIYAGVIKSAFDPPNFPICLLGNRTLSRHGFDVCAKLAWEGNETVTTRLW 318
Query: 356 GFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSS 415
G FC SS+F NATCDEYF NNVT IQGIPG ASG+I ENLWS+YL KG I+E+ S
Sbjct: 319 GLFC-SSRFLNATCDEYFTRNNVTEIQGIPGAASGLIKENLWSSYLTKGVIVERSGMTSV 377
Query: 416 DVLGS----LNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTIL 471
+ ++H YV D+T+ FTLLVGI+FPSVTGIMAGSNRSGDL+DAQKSIP GTIL
Sbjct: 378 GLADGTPIDMDHPYVFSDMTSYFTLLVGIYFPSVTGIMAGSNRSGDLRDAQKSIPTGTIL 437
Query: 472 AILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCG 531
AI TTS VY+S+VVLFGACIEGVVLRDKFG+AV GNLVVGTL+WPSPWVIVIGSFFSTCG
Sbjct: 438 AIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWPSPWVIVIGSFFSTCG 497
Query: 532 AGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLV 591
AGLQSLTGAPRLLQAI++D I+PFL+VFGH KANGEPTWALLLTA I E+GILIASLD V
Sbjct: 498 AGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLTACICEIGILIASLDEV 557
Query: 592 APILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYY 651
APILSMFFLMCY+FVNLACA+QTLLRTPNWRPRFRYYHW LSF+GMS+CLALMFI SWYY
Sbjct: 558 APILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLSFLGMSLCLALMFICSWYY 617
Query: 652 AIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVL 711
A+VAM+IAG+IYKYIEY+GAEKEWGDGIRGLSLSAAR+ALLRLEEGPPHTKNWRPQLLVL
Sbjct: 618 ALVAMLIAGLIYKYIEYRGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVL 677
Query: 712 LKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEK 771
+++D+D +V HP+LL+ SQLKAGKGLTIVGSV+ G FLEN+ +A AE++I+ LMEAEK
Sbjct: 678 VRVDQDQNVVHPQLLSLTSQLKAGKGLTIVGSVLEGTFLENHPQAQRAEESIRRLMEAEK 737
Query: 772 VKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRV 831
VKGFCQ+V+++ LR+G+SHLIQS GLGG++HNTV++GWP WRQ ED + W+ FI VR
Sbjct: 738 VKGFCQVVISSNLRDGVSHLIQSGGLGGLQHNTVLVGWPRNWRQKEDHQTWRNFIELVRE 797
Query: 832 TTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIR 891
TTA HLALLV KN+S FP N E+FSEG+IDVWWIVHDGGMLMLLPFLL+ HKVWRKC +R
Sbjct: 798 TTAGHLALLVTKNVSMFPGNPERFSEGSIDVWWIVHDGGMLMLLPFLLRHHKVWRKCKMR 857
Query: 892 IFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLR 951
IFTVAQ++DNSIQMKKDL TFLYHLRI AEVEVVEMH+SDISAYTYE+TL+MEQRSQ+L+
Sbjct: 858 IFTVAQMDDNSIQMKKDLTTFLYHLRITAEVEVVEMHESDISAYTYEKTLVMEQRSQILK 917
Query: 952 HMRLSKTERDREAQLVKDR-----------NSMLRLT----------------------- 977
M L+K ER+RE Q + D N+ LRL
Sbjct: 918 QMHLTKNEREREIQSITDESRGSIRRKNPANTRLRLNVPEETAGDSEEKPEEEVQLIHDQ 977
Query: 978 ----------SIGSDEDEETETYQEKVHMTWTKDKYMA--SRGQKAKSMEGFQDLLNMRP 1025
S G + + E ET EKVH+TWTKDK +A ++G S EG +D +M+P
Sbjct: 978 SAPSCPSSSPSPGEEPEGEGETDPEKVHLTWTKDKSVAEKNKGPSPVSSEGIKDFFSMKP 1037
Query: 1026 D-----QSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEG 1080
+ QSNVRRMHTAV+LNEVIV KS +AKLVLLNMPGPPRN GDENYMEFLEVLTE
Sbjct: 1038 EWENLNQSNVRRMHTAVRLNEVIVKKSRDAKLVLLNMPGPPRNRNGDENYMEFLEVLTEH 1097
Query: 1081 LERVLLVRGGGSEVITIYS 1099
L+RV+LVRGGG EVITIYS
Sbjct: 1098 LDRVMLVRGGGREVITIYS 1116
>gi|123701900 solute carrier family 12 (potassium/chloride
transporters), member 7 [Homo sapiens]
Length = 1083
Score = 1512 bits (3915), Expect = 0.0
Identities = 749/1048 (71%), Positives = 869/1048 (82%), Gaps = 11/1048 (1%)
Query: 56 DGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEH 115
DG+ + + +LNN E+ + KN+ALFEEEMD+ P VSSLLN++ANYTNL+QG EH
Sbjct: 43 DGNPRENSPFLNNVEVEQESFFEGKNMALFEEEMDSNPMVSSLLNKLANYTNLSQGVVEH 102
Query: 116 EEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLI 175
EE E E +++ K P+MGTF+GVYLPCLQNI GVILFLRLTW+VG AGVL++F IV +
Sbjct: 103 EEDE---ESRRREAKAPRMGTFIGVYLPCLQNILGVILFLRLTWIVGVAGVLESFLIVAM 159
Query: 176 CCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILG 235
CC CTMLTAISMSAIATNGVVPAGGSY+MISR+LGPEFGGAVGLCFYLGTTFA AMYILG
Sbjct: 160 CCTCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILG 219
Query: 236 AIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASL 295
IEIFL YI P AAIF ++ A E+AAML+NMRVYGT LVLM LVVF+GV+YVNK A +
Sbjct: 220 TIEIFLTYISPGAAIFQAEAAGGEAAAMLHNMRVYGTCTLVLMALVVFVGVKYVNKLALV 279
Query: 296 FLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLW 355
FLACV++SILAIYAG IKS+F PP PVC+LGNRTLS R D C K I+N + S LW
Sbjct: 280 FLACVVLSILAIYAGVIKSAFDPPDIPVCLLGNRTLSRRSFDACVKAYGIHNNSATSALW 339
Query: 356 GFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEK---PSA 412
G FCN SQ +A CDEYF+ NNVT IQGIPG ASG+ ENLWS Y G +EK PS
Sbjct: 340 GLFCNGSQP-SAACDEYFIQNNVTEIQGIPGAASGVFLENLWSTYAHAGAFVEKKGVPSV 398
Query: 413 KSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILA 472
++ + YVL DI SFTLLVGI+FPSVTGIMAGSNRSGDLKDAQKSIP GTILA
Sbjct: 399 PVAEESRASALPYVLTDIAASFTLLVGIYFPSVTGIMAGSNRSGDLKDAQKSIPTGTILA 458
Query: 473 ILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGA 532
I+TTSF+YLS +VLFGACIEGVVLRDKFG+A++GNLV+G L+WPSPWVIVIGSFFSTCGA
Sbjct: 459 IVTTSFIYLSCIVLFGACIEGVVLRDKFGEALQGNLVIGMLAWPSPWVIVIGSFFSTCGA 518
Query: 533 GLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVA 592
GLQSLTGAPRLLQAIA+D I+PFL+VFGH KANGEPTWALLLT I E GILIASLD VA
Sbjct: 519 GLQSLTGAPRLLQAIARDGIVPFLQVFGHGKANGEPTWALLLTVLICETGILIASLDSVA 578
Query: 593 PILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYA 652
PILSMFFLMCYLFVNLACA+QTLLRTPNWRPRF++YHW LSF+GMS+CLALMFI SWYYA
Sbjct: 579 PILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKFYHWTLSFLGMSLCLALMFICSWYYA 638
Query: 653 IVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLL 712
+ AM+IAG IYKYIEY+GAEKEWGDGIRGLSL+AAR+ALLR+E GPPHTKNWRPQ+LV+L
Sbjct: 639 LSAMLIAGCIYKYIEYRGAEKEWGDGIRGLSLNAARYALLRVEHGPPHTKNWRPQVLVML 698
Query: 713 KLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKV 772
LD + VKHPRLL+F SQLKAGKGLTIVGSV+ G +L+ + EA AE+ I+ LM EK
Sbjct: 699 NLDAEQAVKHPRLLSFTSQLKAGKGLTIVGSVLEGTYLDKHMEAQRAEENIRSLMSTEKT 758
Query: 773 KGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVT 832
KGFCQLVV++ LR+G+SHLIQS GLGG+KHNTV+M WP W+Q ++ +WK F+ TVR T
Sbjct: 759 KGFCQLVVSSSLRDGMSHLIQSAGLGGLKHNTVLMAWPASWKQEDNPFSWKNFVDTVRDT 818
Query: 833 TAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRI 892
TAAH ALLVAKN+ FP N E+F G+IDVWWIVHDGGMLMLLPFLL+QHKVWRKC +RI
Sbjct: 819 TAAHQALLVAKNVDSFPQNQERFGGGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRI 878
Query: 893 FTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRH 952
FTVAQ++DNSIQMKKDL FLYHLRI AEVEVVEM ++DISA+TYERTLMMEQRSQML+
Sbjct: 879 FTVAQVDDNSIQMKKDLQMFLYHLRISAEVEVVEMVENDISAFTYERTLMMEQRSQMLKQ 938
Query: 953 MRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASR-GQKA 1011
M+LSK E++REAQL+ DRN+ + + T +KV MTWT++K +A + +
Sbjct: 939 MQLSKNEQEREAQLIHDRNTASHTAAAARTQAPPT---PDKVQMTWTREKLIAEKYRSRD 995
Query: 1012 KSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYM 1071
S+ GF+DL +M+PDQSNVRRMHTAVKLN V++NKS +A+LVLLNMPGPP+N +GDENYM
Sbjct: 996 TSLSGFKDLFSMKPDQSNVRRMHTAVKLNGVVLNKSQDAQLVLLNMPGPPKNRQGDENYM 1055
Query: 1072 EFLEVLTEGLERVLLVRGGGSEVITIYS 1099
EFLEVLTEGL RVLLVRGGG EVITIYS
Sbjct: 1056 EFLEVLTEGLNRVLLVRGGGREVITIYS 1083
>gi|186910319 solute carrier family 12, member 3 isoform 3 [Homo
sapiens]
Length = 1021
Score = 239 bits (610), Expect = 1e-62
Identities = 199/743 (26%), Positives = 328/743 (44%), Gaps = 139/743 (18%)
Query: 433 SFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIE 492
+F + IFFPS TGI+AG+N SGDLKD +IP GT++AI T+ YL+ G+C
Sbjct: 339 TFFGMFSIFFPSATGILAGANISGDLKDPAIAIPKGTLMAIFWTTISYLAISATIGSC-- 396
Query: 493 GVVLRDKFGDAVKGNLVVG---------------------------------TLSWPSPW 519
V+RD G + + G T+S S +
Sbjct: 397 --VVRDASG-VLNDTVTPGWGACEGLACSYGWNFTECTQQHSCHYGLINYYQTMSMVSGF 453
Query: 520 --VIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTA 576
+I G F +T + L L A ++ Q + +D + P + FG N EP LL
Sbjct: 454 APLITAGIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFFGKGYGKNKEPVRGYLLAY 513
Query: 577 AIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMG 636
AIA I+IA L+ +API+S FFL Y +N +C ++ +P WRP F+YY+ + G
Sbjct: 514 AIAVAFIIIAELNTIAPIISNFFLCSYALINFSCFHASITNSPGWRPSFQYYNKWAALFG 573
Query: 637 MSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEE 696
I + +MF+ +W+ A++A+ + + Y+ Y+ E WG ++ S + A + L E
Sbjct: 574 AIISVVIMFLLTWWAALIAIGVVLFLLLYVIYKKPEVNWGSSVQAGSYNLALSYSVGLNE 633
Query: 697 GPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEA 756
H KN+RPQ LVL P L+ F L I G V++G + E
Sbjct: 634 VEDHIKNYRPQCLVLTGPPN----FRPALVDFVGTFTRNLSLMICGHVLIGPHKQRMPEL 689
Query: 757 LAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQS 816
+ K+K F V+A LR G+ L+Q+ GLG MK N +V+G+ W+ +
Sbjct: 690 QLIANGHTKWLNKRKIKAFYSDVIAEDLRRGVQILMQAAGLGRMKPNILVVGFKKNWQSA 749
Query: 817 EDARAWKTFIG-------------TVRVTTAAHLALLVAKNIS--FFP------------ 849
A + +IG +R+ +++ ++ +I+ F P
Sbjct: 750 HPATV-EDYIGILHDAFDFNYGVCVMRMREGLNVSKMMQAHINPVFDPAEDGKEASARVD 808
Query: 850 ----------SNVEQFSEG--NIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQ 897
+ + Q +G ID++W+ DGG+ +L+P+LL + + W KC IR+F Q
Sbjct: 809 PKALVKEEQATTIFQSEQGKKTIDIYWLFDDGGLTLLIPYLLGRKRRWSKCKIRVFVGGQ 868
Query: 898 LEDNSIQMKKDLATFLYHLRIE-AEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLS 956
+ + Q +K + + L R+ EV ++ + + A E T E M+ RL+
Sbjct: 869 I-NRMDQERKAIISLLSKFRLGFHEVHILPDINQNPRA---EHTKRFE---DMIAPFRLN 921
Query: 957 KTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEG 1016
+D R+ +++ DEE TK++ + R
Sbjct: 922 DGFKDEATVNEMRRDCPWKIS------DEEI-----------TKNRVKSLR--------- 955
Query: 1017 FQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEV 1076
V+LNE++++ S +A L+++ +P + YM +LE
Sbjct: 956 -------------------QVRLNEIVLDYSRDAALIVITLPIGRKGKCPSSLYMAWLET 996
Query: 1077 LTEGLE-RVLLVRGGGSEVITIY 1098
L++ L V+L+RG V+T Y
Sbjct: 997 LSQDLRPPVILIRGNQENVLTFY 1019
Score = 123 bits (308), Expect = 1e-27
Identities = 69/207 (33%), Positives = 112/207 (54%), Gaps = 21/207 (10%)
Query: 117 EAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLIC 176
E E T +K P + + G GV + C+ NI+GVIL+LRL W+ AG++ + I+L+
Sbjct: 119 EGEAGTSSEKNPEEPVRFGWVKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWIIILLS 178
Query: 177 CCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGA 236
T +T +S+SAI+TNG V +GG+YF+ISR+LGPE GG++GL F AM+ +G
Sbjct: 179 VTVTSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGSIGLIFAFANAVGVAMHTVGF 238
Query: 237 IEIFLVYIVPRAAIFHSDDALKESAA----MLNNMRVYGTAFLVLMVLVVFIGVRYVNKF 292
E D L+E A +N++R+ G + +++ + G+ + +K
Sbjct: 239 AETV-------------RDLLQEYGAPIVDPINDIRIIGVVSVTVLLAISLAGMEWESKA 285
Query: 293 ASLFLACVIVSILAIYAGAIKSSFAPP 319
LF ++VS +A + + PP
Sbjct: 286 QVLFFLVIMVS----FANYLVGTLIPP 308
>gi|186910317 solute carrier family 12, member 3 isoform 2 [Homo
sapiens]
Length = 1029
Score = 236 bits (601), Expect = 1e-61
Identities = 199/752 (26%), Positives = 328/752 (43%), Gaps = 148/752 (19%)
Query: 433 SFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIE 492
+F + IFFPS TGI+AG+N SGDLKD +IP GT++AI T+ YL+ G+C
Sbjct: 338 TFFGMFSIFFPSATGILAGANISGDLKDPAIAIPKGTLMAIFWTTISYLAISATIGSC-- 395
Query: 493 GVVLRDKFGDAVKGNLVVG---------------------------------TLSWPSPW 519
V+RD G + + G T+S S +
Sbjct: 396 --VVRDASG-VLNDTVTPGWGACEGLACSYGWNFTECTQQHSCHYGLINYYQTMSMVSGF 452
Query: 520 --VIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTA 576
+I G F +T + L L A ++ Q + +D + P + FG N EP LL
Sbjct: 453 APLITAGIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFFGKGYGKNKEPVRGYLLAY 512
Query: 577 AIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMG 636
AIA I+IA L+ +API+S FFL Y +N +C ++ +P WRP F+YY+ + G
Sbjct: 513 AIAVAFIIIAELNTIAPIISNFFLCSYALINFSCFHASITNSPGWRPSFQYYNKWAALFG 572
Query: 637 MSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEE 696
I + +MF+ +W+ A++A+ + + Y+ Y+ E WG ++ S + A + L E
Sbjct: 573 AIISVVIMFLLTWWAALIAIGVVLFLLLYVIYKKPEVNWGSSVQAGSYNLALSYSVGLNE 632
Query: 697 GPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEA 756
H KN+RPQ LVL P L+ F L I G V++G + E
Sbjct: 633 VEDHIKNYRPQCLVLTGPPN----FRPALVDFVGTFTRNLSLMICGHVLIGPHKQRMPEL 688
Query: 757 LAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQS 816
+ K+K F V+A LR G+ L+Q+ GLG MK N +V+G+ W+ +
Sbjct: 689 QLIANGHTKWLNKRKIKAFYSDVIAEDLRRGVQILMQAAGLGRMKPNILVVGFKKNWQSA 748
Query: 817 EDARAWKTFIG-------------TVRVTTAAHLALLVAKNIS--FFP------------ 849
A + +IG +R+ +++ ++ +I+ F P
Sbjct: 749 HPATV-EDYIGILHDAFDFNYGVCVMRMREGLNVSKMMQAHINPVFDPAEDGKEASARGA 807
Query: 850 -------------------SNVEQFSEG--NIDVWWIVHDGGMLMLLPFLLKQHKVWRKC 888
+ + Q +G ID++W+ DGG+ +L+P+LL + + W KC
Sbjct: 808 RPSVSGALDPKALVKEEQATTIFQSEQGKKTIDIYWLFDDGGLTLLIPYLLGRKRRWSKC 867
Query: 889 SIRIFTVAQLEDNSIQMKKDLATFLYHLRIE-AEVEVVEMHDSDISAYTYERTLMMEQRS 947
IR+F Q+ + Q +K + + L R+ EV ++ + + A E T E
Sbjct: 868 KIRVFVGGQI-NRMDQERKAIISLLSKFRLGFHEVHILPDINQNPRA---EHTKRFE--- 920
Query: 948 QMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASR 1007
M+ RL+ +D R+ +++ DEE TK++ + R
Sbjct: 921 DMIAPFRLNDGFKDEATVNEMRRDCPWKIS------DEEI-----------TKNRVKSLR 963
Query: 1008 GQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGD 1067
V+LNE++++ S +A L+++ +P +
Sbjct: 964 ----------------------------QVRLNEIVLDYSRDAALIVITLPIGRKGKCPS 995
Query: 1068 ENYMEFLEVLTEGLE-RVLLVRGGGSEVITIY 1098
YM +LE L++ L V+L+RG V+T Y
Sbjct: 996 SLYMAWLETLSQDLRPPVILIRGNQENVLTFY 1027
Score = 123 bits (308), Expect = 1e-27
Identities = 69/207 (33%), Positives = 112/207 (54%), Gaps = 21/207 (10%)
Query: 117 EAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLIC 176
E E T +K P + + G GV + C+ NI+GVIL+LRL W+ AG++ + I+L+
Sbjct: 118 EGEAGTSSEKNPEEPVRFGWVKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWIIILLS 177
Query: 177 CCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGA 236
T +T +S+SAI+TNG V +GG+YF+ISR+LGPE GG++GL F AM+ +G
Sbjct: 178 VTVTSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGSIGLIFAFANAVGVAMHTVGF 237
Query: 237 IEIFLVYIVPRAAIFHSDDALKESAA----MLNNMRVYGTAFLVLMVLVVFIGVRYVNKF 292
E D L+E A +N++R+ G + +++ + G+ + +K
Sbjct: 238 AETV-------------RDLLQEYGAPIVDPINDIRIIGVVSVTVLLAISLAGMEWESKA 284
Query: 293 ASLFLACVIVSILAIYAGAIKSSFAPP 319
LF ++VS +A + + PP
Sbjct: 285 QVLFFLVIMVS----FANYLVGTLIPP 307
>gi|186910315 solute carrier family 12, member 3 isoform 1 [Homo
sapiens]
Length = 1030
Score = 236 bits (601), Expect = 1e-61
Identities = 199/752 (26%), Positives = 328/752 (43%), Gaps = 148/752 (19%)
Query: 433 SFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIE 492
+F + IFFPS TGI+AG+N SGDLKD +IP GT++AI T+ YL+ G+C
Sbjct: 339 TFFGMFSIFFPSATGILAGANISGDLKDPAIAIPKGTLMAIFWTTISYLAISATIGSC-- 396
Query: 493 GVVLRDKFGDAVKGNLVVG---------------------------------TLSWPSPW 519
V+RD G + + G T+S S +
Sbjct: 397 --VVRDASG-VLNDTVTPGWGACEGLACSYGWNFTECTQQHSCHYGLINYYQTMSMVSGF 453
Query: 520 --VIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTWALLLTA 576
+I G F +T + L L A ++ Q + +D + P + FG N EP LL
Sbjct: 454 APLITAGIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFFGKGYGKNKEPVRGYLLAY 513
Query: 577 AIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMG 636
AIA I+IA L+ +API+S FFL Y +N +C ++ +P WRP F+YY+ + G
Sbjct: 514 AIAVAFIIIAELNTIAPIISNFFLCSYALINFSCFHASITNSPGWRPSFQYYNKWAALFG 573
Query: 637 MSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEE 696
I + +MF+ +W+ A++A+ + + Y+ Y+ E WG ++ S + A + L E
Sbjct: 574 AIISVVIMFLLTWWAALIAIGVVLFLLLYVIYKKPEVNWGSSVQAGSYNLALSYSVGLNE 633
Query: 697 GPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEA 756
H KN+RPQ LVL P L+ F L I G V++G + E
Sbjct: 634 VEDHIKNYRPQCLVLTGPPN----FRPALVDFVGTFTRNLSLMICGHVLIGPHKQRMPEL 689
Query: 757 LAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQS 816
+ K+K F V+A LR G+ L+Q+ GLG MK N +V+G+ W+ +
Sbjct: 690 QLIANGHTKWLNKRKIKAFYSDVIAEDLRRGVQILMQAAGLGRMKPNILVVGFKKNWQSA 749
Query: 817 EDARAWKTFIG-------------TVRVTTAAHLALLVAKNIS--FFP------------ 849
A + +IG +R+ +++ ++ +I+ F P
Sbjct: 750 HPATV-EDYIGILHDAFDFNYGVCVMRMREGLNVSKMMQAHINPVFDPAEDGKEASARGA 808
Query: 850 -------------------SNVEQFSEG--NIDVWWIVHDGGMLMLLPFLLKQHKVWRKC 888
+ + Q +G ID++W+ DGG+ +L+P+LL + + W KC
Sbjct: 809 RPSVSGALDPKALVKEEQATTIFQSEQGKKTIDIYWLFDDGGLTLLIPYLLGRKRRWSKC 868
Query: 889 SIRIFTVAQLEDNSIQMKKDLATFLYHLRIE-AEVEVVEMHDSDISAYTYERTLMMEQRS 947
IR+F Q+ + Q +K + + L R+ EV ++ + + A E T E
Sbjct: 869 KIRVFVGGQI-NRMDQERKAIISLLSKFRLGFHEVHILPDINQNPRA---EHTKRFE--- 921
Query: 948 QMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASR 1007
M+ RL+ +D R+ +++ DEE TK++ + R
Sbjct: 922 DMIAPFRLNDGFKDEATVNEMRRDCPWKIS------DEEI-----------TKNRVKSLR 964
Query: 1008 GQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGD 1067
V+LNE++++ S +A L+++ +P +
Sbjct: 965 ----------------------------QVRLNEIVLDYSRDAALIVITLPIGRKGKCPS 996
Query: 1068 ENYMEFLEVLTEGLE-RVLLVRGGGSEVITIY 1098
YM +LE L++ L V+L+RG V+T Y
Sbjct: 997 SLYMAWLETLSQDLRPPVILIRGNQENVLTFY 1028
Score = 123 bits (308), Expect = 1e-27
Identities = 69/207 (33%), Positives = 112/207 (54%), Gaps = 21/207 (10%)
Query: 117 EAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLIC 176
E E T +K P + + G GV + C+ NI+GVIL+LRL W+ AG++ + I+L+
Sbjct: 119 EGEAGTSSEKNPEEPVRFGWVKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWIIILLS 178
Query: 177 CCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGA 236
T +T +S+SAI+TNG V +GG+YF+ISR+LGPE GG++GL F AM+ +G
Sbjct: 179 VTVTSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGSIGLIFAFANAVGVAMHTVGF 238
Query: 237 IEIFLVYIVPRAAIFHSDDALKESAA----MLNNMRVYGTAFLVLMVLVVFIGVRYVNKF 292
E D L+E A +N++R+ G + +++ + G+ + +K
Sbjct: 239 AETV-------------RDLLQEYGAPIVDPINDIRIIGVVSVTVLLAISLAGMEWESKA 285
Query: 293 ASLFLACVIVSILAIYAGAIKSSFAPP 319
LF ++VS +A + + PP
Sbjct: 286 QVLFFLVIMVS----FANYLVGTLIPP 308
>gi|4506975 solute carrier family 12 (sodium/potassium/chloride
transporters), member 2 [Homo sapiens]
Length = 1212
Score = 223 bits (567), Expect = 1e-57
Identities = 147/421 (34%), Positives = 215/421 (51%), Gaps = 46/421 (10%)
Query: 433 SFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIE 492
+F + IFFP+ TGI+AG+N SGDL D Q +IP GT+LAIL T+ VY+ V G+C
Sbjct: 486 TFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITTLVYVGIAVSVGSC-- 543
Query: 493 GVVLRDKFGD---------------AVKGNL-------------------VVGTLSWPSP 518
V+RD G+ A K N V+ +S +P
Sbjct: 544 --VVRDATGNVNDTIVTELTNCTSAACKLNFDFSSCESSPCSYGLMNNFQVMSMVSGFTP 601
Query: 519 WVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVF--GHSKANGEPTWALLLTA 576
+I G F +T + L SL AP++ QA+ KDNI P ++F G+ K N EP +LT
Sbjct: 602 -LISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGK-NNEPLRGYILTF 659
Query: 577 AIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMG 636
IA ILIA L+++API+S FFL Y +N + +L ++P WRP F+YY+ +S +G
Sbjct: 660 LIALGFILIAELNVIAPIISNFFLASYALINFSVFHASLAKSPGWRPAFKYYNMWISLLG 719
Query: 637 MSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEE 696
+C +MF+ +W+ A++ VI +Y Y+ Y+ + WG + L+ A +RL
Sbjct: 720 AILCCIVMFVINWWAALLTYVIVLGLYIYVTYKKPDVNWGSSTQALTYLNALQHSIRLSG 779
Query: 697 GPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEA 756
H KN+RPQ LV+ P LL GL I G V +G + E
Sbjct: 780 VEDHVKNFRPQCLVMTGAPN----SRPALLHLVHDFTKNVGLMICGHVHMGPRRQAMKEM 835
Query: 757 LAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQS 816
+ + + K+K F V A LREG +L+Q+ GLG MK NT+V+G+ W Q+
Sbjct: 836 SIDQAKYQRWLIKNKMKAFYAPVHADDLREGAQYLMQAAGLGRMKPNTLVLGFKKDWLQA 895
Query: 817 E 817
+
Sbjct: 896 D 896
Score = 122 bits (307), Expect = 1e-27
Identities = 90/315 (28%), Positives = 151/315 (47%), Gaps = 42/315 (13%)
Query: 17 AASISQEPSLADI--------KARIQDSDEPDLSQNSI--------TGEHSQLLDDGHKK 60
AAS S E SL+D Q+ + LS+ S +G H D H
Sbjct: 147 AASSSAEDSLSDAAGVGVDGPNVSFQNGGDTVLSEGSSLHSGGGGGSGHHQHYYYDTH-- 204
Query: 61 ARNAYLNNSNYEEGD-----EYFDKNLALFEEEMDTRPKVSSLLNRMAN------YTNLT 109
YL + D +++ A E++ RP ++ L + + + N
Sbjct: 205 TNTYYLRTFGHNTMDAVPRIDHYRHTAAQLGEKL-LRPSLAELHDELEKEPFEDGFANGE 263
Query: 110 QGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQA 169
+ + T K K G GV + C+ NI+GV+LF+RL+W+VG AG+ +
Sbjct: 264 ESTPTRDAVVTYTAESKGVVK---FGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLS 320
Query: 170 FAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAA 229
++++ T +T +S SAIATNG V GG+Y++ISR+LGPEFGGA+GL F A
Sbjct: 321 VLVIMMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAV 380
Query: 230 AMYILGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYV 289
AMY++G E +V ++ +I D+ +N++R+ G +V+++ + G+ +
Sbjct: 381 AMYVVGFAET-VVELLKEHSILMIDE--------INDIRIIGAITVVILLGISVAGMEWE 431
Query: 290 NKFASLFLACVIVSI 304
K + L ++++I
Sbjct: 432 AKAQIVLLVILLLAI 446
Score = 76.6 bits (187), Expect = 1e-13
Identities = 58/245 (23%), Positives = 110/245 (44%), Gaps = 55/245 (22%)
Query: 857 EGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQM-KKDLATFLYH 915
+ IDVWW+ DGG+ +L+P+LL K W+ C IR+F ++ N I ++ +AT L
Sbjct: 1021 KNTIDVWWLFDDGGLTLLIPYLLTTKKKWKDCKIRVFIGGKI--NRIDHDRRAMATLLSK 1078
Query: 916 LRIE-AEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSML 974
RI+ +++ V+ DI+ + ++ + +++ RL + +++++ +
Sbjct: 1079 FRIDFSDIMVL----GDINTKPKKENIIAFE--EIIEPYRLHEDDKEQDIADKMKEDEPW 1132
Query: 975 RLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMH 1034
R+T D E E Y+ K +
Sbjct: 1133 RIT------DNELELYKTKT---------------------------------------Y 1147
Query: 1035 TAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEV 1094
++LNE++ S A ++++++P + YM +LE L++ L +LLVRG V
Sbjct: 1148 RQIRLNELLKEHSSTANIIVMSLPVARKGAVSSALYMAWLEALSKDLPPILLVRGNHQSV 1207
Query: 1095 ITIYS 1099
+T YS
Sbjct: 1208 LTFYS 1212
>gi|134254459 sodium potassium chloride cotransporter 2 [Homo
sapiens]
Length = 1099
Score = 211 bits (538), Expect = 2e-54
Identities = 142/421 (33%), Positives = 207/421 (49%), Gaps = 50/421 (11%)
Query: 434 FTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEG 493
F + IFFP+ TGI+AG+N SGDL+D Q +IP GT+LAI T+ YL + GAC
Sbjct: 380 FFSVFAIFFPAATGILAGANISGDLEDPQDAIPRGTMLAIFITTVAYLGVAICVGAC--- 436
Query: 494 VVLRDKFGDA---------VKGNLVVG----------------------TLSWPSPW--V 520
V+RD G+ G+ G +S S + +
Sbjct: 437 -VVRDATGNMNDTIISGMNCNGSAACGLGYDFSRCRHEPCQYGLMNNFQVMSMVSGFGPL 495
Query: 521 IVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVF--GHSKANGEPTWALLLTAAI 578
I G F +T + L SL AP++ QA+ KDNI L+ F G+ K N EP +LT I
Sbjct: 496 ITAGIFSATLSSALASLVSAPKVFQALCKDNIYKALQFFAKGYGK-NNEPLRGYILTFLI 554
Query: 579 AELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMS 638
A ILIA L+ +API+S FFL Y +N +C + ++P WRP + Y+ +S G
Sbjct: 555 AMAFILIAELNTIAPIISNFFLASYALINFSCFHASYAKSPGWRPAYGIYNMWVSLFGAV 614
Query: 639 ICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGP 698
+C A+MF+ +W+ A++ VI +Y Y+ + + WG + LS +A L L
Sbjct: 615 LCCAVMFVINWWAAVITYVIEFFLYVYVTCKKPDVNWGSSTQALSYVSALDNALELTTVE 674
Query: 699 PHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGN---FLENYGE 755
H KN+RPQ +VL + P LL GL I V VG ++
Sbjct: 675 DHVKNFRPQCIVL----TGGPMTRPALLDITHAFTKNSGLCICCEVFVGPRKLCVKEMNS 730
Query: 756 ALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQ 815
+A +Q + K+K F V A R+G+ L+Q+ GLG MK NT+V+G+ WR+
Sbjct: 731 GMAKKQA---WLIKNKIKAFYAAVAADCFRDGVRSLLQASGLGRMKPNTLVIGYKKNWRK 787
Query: 816 S 816
+
Sbjct: 788 A 788
Score = 132 bits (331), Expect = 2e-30
Identities = 83/253 (32%), Positives = 135/253 (53%), Gaps = 25/253 (9%)
Query: 65 YLNNSNYEEGDEYFDKNLALFEEEMDTRPKVS-SLLNRMANYTNLTQGAKEHEEAENITE 123
Y N+ G + +L E++ V+ S +R+AN G E+AEN +
Sbjct: 114 YYRNTGSISGPKVNRPSLLEIHEQLAKNVAVTPSSADRVAN----GDGIPGDEQAENKED 169
Query: 124 GKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLT 183
+ K G GV + C+ NI+GV+LF+RL+W+VG AG+ I+L+ T +T
Sbjct: 170 DQAGVVK---FGWVKGVLVRCMLNIWGVMLFIRLSWIVGEAGIGLGVLIILLSTMVTSIT 226
Query: 184 AISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVY 243
+S SAIATNG V GG+Y++ISR+LGPEFGG++GL F A AMY++G E +
Sbjct: 227 GLSTSAIATNGFVRGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVV-- 284
Query: 244 IVPRAAIFHSDDALKESAAML----NNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLAC 299
D LKES +M+ N++R+ G+ +V+++ + G+ + K + L
Sbjct: 285 -----------DLLKESDSMMVDPTNDIRIIGSITVVILLGISVAGMEWEAKAQVILLVI 333
Query: 300 VIVSILAIYAGAI 312
++++I + G +
Sbjct: 334 LLIAIANFFIGTV 346
Score = 85.5 bits (210), Expect = 3e-16
Identities = 68/275 (24%), Positives = 124/275 (45%), Gaps = 55/275 (20%)
Query: 827 GTVRVTTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWR 886
G++ + + H+ K + ++ +G IDVWW+ DGG+ +L+P++L K W+
Sbjct: 878 GSINTSQSMHVGEFNQKLVEASTQFKKKQEKGTIDVWWLFDDGGLTLLIPYILTLRKKWK 937
Query: 887 KCSIRIFTVAQLEDNSIQMKK-DLATFLYHLRIE-AEVEVVEMHDSDISAYTYERTLMME 944
C +RI+ ++ N I+ +K +A+ L RI+ A++ ++ DI+ + + +
Sbjct: 938 DCKLRIYVGGKI--NRIEEEKIVMASLLSKFRIKFADIHII----GDINIRPNKESWKVF 991
Query: 945 QRSQMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYM 1004
+ +M+ RL ++ +D R + ++T D E E +EK
Sbjct: 992 E--EMIEPYRLHESCKDLTTAEKLKRETPWKIT------DAELEAVKEK----------- 1032
Query: 1005 ASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNP 1064
+ V+LNE++ S A L++L++P +
Sbjct: 1033 ----------------------------SYRQVRLNELLQEHSRAANLIVLSLPVARKGS 1064
Query: 1065 EGDENYMEFLEVLTEGLERVLLVRGGGSEVITIYS 1099
D YM +LE+LT+ L VLLVRG V+T YS
Sbjct: 1065 ISDLLYMAWLEILTKNLPPVLLVRGNHKNVLTFYS 1099
>gi|31881740 solute carrier family 12 (potassium/chloride
transporters), member 9 [Homo sapiens]
Length = 914
Score = 195 bits (496), Expect = 2e-49
Identities = 130/412 (31%), Positives = 214/412 (51%), Gaps = 37/412 (8%)
Query: 411 SAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTI 470
S+ D LG+ E +F + + F TGIMAG+N SG+LKD ++IP+GTI
Sbjct: 244 SSTLKDNLGAGYAEDYTTGAVMNFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPLGTI 303
Query: 471 LAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTC 530
+A+ T FVY+ L + +L++ +G +L WP +++IG + +
Sbjct: 304 VAVAYTFFVYVLLFFLSSFTCDRTLLQEDYGFFRAISL------WPP--LVLIGIYATAL 355
Query: 531 GAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTA-AIAELGILIASLD 589
A + SL GA R+L A+A+D++ + + G WA +L + + +L +L L+
Sbjct: 356 SASMSSLIGASRILHALARDDLFGVILAPAKVVSRGGNPWAAVLYSWGLVQLVLLAGKLN 415
Query: 590 LVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSW 649
+A ++++F+L+ Y V+L+C PN+RP F + W +G++ CL +MF+ S
Sbjct: 416 TLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISP 475
Query: 650 YYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLL 709
A ++++ G++ + +G WG + L R LLRL+ H K WRPQLL
Sbjct: 476 GAAGGSLLLMGLLAALLTARGGPSSWGYVSQALLFHQVRKYLLRLDVRKDHVKFWRPQLL 535
Query: 710 VLLKLDEDLHVKHPR----LLTFASQLKAGKGLTIVGSVIVGNF--------LENYGEAL 757
+L V +PR LL A+QLK G GL ++G V +G+ YG L
Sbjct: 536 LL--------VGNPRGALPLLRLANQLKKG-GLYVLGHVTLGDLDSLPSDPVQPQYGAWL 586
Query: 758 AAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGW 809
+ L++ +VK F L ++ +R+G HL++ GLGGMK NT+V+G+
Sbjct: 587 S-------LVDRAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGF 631
Score = 112 bits (279), Expect = 3e-24
Identities = 53/109 (48%), Positives = 77/109 (70%)
Query: 133 QMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIAT 192
++ TF+GV +P + ++F +++FLR+ +VVG AG+LQA A++L+ LT +S+ AIAT
Sbjct: 36 KLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYFILALTVLSVCAIAT 95
Query: 193 NGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFL 241
NG V GG+YFMISR LGPE GG++GL FYL A+ +LG +E L
Sbjct: 96 NGAVQGGGAYFMISRTLGPEVGGSIGLMFYLANVCGCAVSLLGLVESVL 144
Score = 31.6 bits (70), Expect = 4.3
Identities = 16/38 (42%), Positives = 19/38 (50%)
Query: 1052 LVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRG 1089
L L +P PP +P Y+ LE LT L LLV G
Sbjct: 868 LTFLYLPRPPADPARYPRYLALLETLTRDLGPTLLVHG 905
>gi|38569457 solute carrier family 12, member 8 [Homo sapiens]
Length = 714
Score = 104 bits (260), Expect = 4e-22
Identities = 59/176 (33%), Positives = 102/176 (57%), Gaps = 9/176 (5%)
Query: 433 SFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIE 492
SF + G+FFP+ TG+MAG N GDL++ SIP+G++ A+ + F+Y+ V L GA
Sbjct: 232 SFFTVFGVFFPAATGVMAGFNMGGDLREPAASIPLGSLAAVGISWFLYIVFVFLLGAICT 291
Query: 493 GVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNI 552
LR F A K +L+ ++ ++G + S+ + + L GAPR+LQ IA++ +
Sbjct: 292 REALRYDFLIAEKVSLM--------GFLFLLGLYISSLASCMGGLYGAPRILQCIAQEKV 343
Query: 553 IPFLRVFGHSKA-NGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVN 607
IP L G K N P A+ LT+ + + + ++++API+++ F++ Y+ V+
Sbjct: 344 IPALACLGQGKGPNKTPVAAICLTSLVTMAFVFVGQVNVLAPIVTINFMLTYVAVD 399
Score = 90.9 bits (224), Expect = 6e-18
Identities = 62/207 (29%), Positives = 94/207 (45%), Gaps = 27/207 (13%)
Query: 115 HEEAENITEGKKKPTKTPQM--------GTFMGVYLPCLQNIFGVILFLRLTWVVGTAGV 166
HE A+ + +P Q+ GT+ GV+ C+ NIFGV+LFLR W+VG GV
Sbjct: 12 HEAAQQDALAQPQPWWKTQLFMWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGV 71
Query: 167 LQAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTT 226
L +V ++T +S + + +GG Y MIS LG + GG +GL + G
Sbjct: 72 LLGMFLVSFVILVALVTVLSGIGVGERSSIGSGGVYSMISSVLGGQTGGTIGLLYVFGQC 131
Query: 227 FAAAMYILGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVL--VVFI 284
A AMYI G E ++ + + N V G + VL+ L +
Sbjct: 132 VAGAMYITGFAE-----------------SISDLLGLGNIWAVRGISVAVLLALLGINLA 174
Query: 285 GVRYVNKFASLFLACVIVSILAIYAGA 311
GV+++ + L L + VS L G+
Sbjct: 175 GVKWIIRLQLLLLFLLAVSTLDFVVGS 201
Score = 33.1 bits (74), Expect = 1.5
Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 16/79 (20%)
Query: 621 WRPRFRYYH-----WALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEW 675
WR +Y W +S +G L +MF+ W Y +V M +A ++Y YI
Sbjct: 582 WRRSTSFYTHMCNPW-VSLLGAVGSLLIMFVIQWVYTLVNMGVAAIVYFYI--------- 631
Query: 676 GDGIRGLSL-SAARFALLR 693
G GL L SA+ F+ R
Sbjct: 632 GRASPGLHLGSASNFSFFR 650
>gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo
sapiens]
Length = 697
Score = 47.0 bits (110), Expect = 1e-04
Identities = 51/211 (24%), Positives = 83/211 (39%), Gaps = 21/211 (9%)
Query: 408 EKPSAKSSDVLGS-----LNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQ 462
E PS + + G+ L T F VG + TG ++++ Q
Sbjct: 274 EPPSENGTSIYGAGGFMPYGFTGTLAGAATCFYAFVGFDCIATTG--------EEVRNPQ 325
Query: 463 KSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW-PSPWVI 521
K+IPIG + ++L Y + +L +K V V W P+ +V+
Sbjct: 326 KAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDEKSPLPVAFEYV----GWGPAKYVV 381
Query: 522 VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAEL 581
GS + + L S+ PR+L A+A+D ++ R P A L I+ L
Sbjct: 382 AAGSLCALSTSLLGSMFPLPRILFAMARDGLL--FRFLARVSKRQSPVAATLTAGVISAL 439
Query: 582 GILIASLDLVAPILSMFFLMCYLFVNLACAL 612
+ L + ++S+ LM Y V AC L
Sbjct: 440 MAFLFDLKALVDMMSIGTLMAYSLV-AACVL 469
>gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo
sapiens]
Length = 658
Score = 45.8 bits (107), Expect = 2e-04
Identities = 51/211 (24%), Positives = 87/211 (41%), Gaps = 20/211 (9%)
Query: 408 EKPSAKSSDVLGS-----LNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQ 462
E PS + + G+ L T F VG + TG ++++ Q
Sbjct: 234 EPPSENGTSIYGAGGFMPYGFTGTLAGAATCFYAFVGFDCIATTG--------EEVRNPQ 285
Query: 463 KSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW-PSPWVI 521
K+IPIG + ++L Y + +L +K V V W P+ +V+
Sbjct: 286 KAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDEKSPLPVAFEYV----GWGPAKYVV 341
Query: 522 VIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAEL 581
GS + + L S+ PR++ A+A+D ++ F + + P A L + A+A L
Sbjct: 342 AAGSLCALSTSLLGSIFPMPRVIYAMAEDGLL-FKCLAQINSKTKTPIIATLSSGAVAAL 400
Query: 582 GILIASLDLVAPILSMFFLMCYLFVNLACAL 612
+ L + ++S+ LM Y V AC L
Sbjct: 401 MAFLFDLKALVDMMSIGTLMAYSLV-AACVL 430
>gi|4507047 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 1 [Homo sapiens]
Length = 629
Score = 40.4 bits (93), Expect = 0.009
Identities = 48/208 (23%), Positives = 89/208 (42%), Gaps = 27/208 (12%)
Query: 426 VLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLS--- 482
VL T F VG + TG ++K+ QK+IP+G + ++L Y
Sbjct: 255 VLSGAATCFYAFVGFDCIATTG--------EEVKNPQKAIPVGIVASLLICFIAYFGVSA 306
Query: 483 --NVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWP-SPWVIVIGSFFSTCGAGLQSLTG 539
+++ C++ DA K + W + + + +GS + + L S+
Sbjct: 307 ALTLMMPYFCLDN---NSPLPDAFK------HVGWEGAKYAVAVGSLCALSASLLGSMFP 357
Query: 540 APRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFF 599
PR++ A+A+D ++ F + + P A L + A+A + + L + ++S+
Sbjct: 358 MPRVIYAMAEDGLL-FKFLANVNDRTKTPIIATLASGAVAAVMAFLFDLKDLVDLMSIGT 416
Query: 600 LMCYLFVNLACALQTLLRTPNWRPRFRY 627
L+ Y V AC L +LR +P Y
Sbjct: 417 LLAYSLV-AACVL--VLRYQPEQPNLVY 441
>gi|9790235 solute carrier family 7, member 10 [Homo sapiens]
Length = 523
Score = 37.4 bits (85), Expect = 0.079
Identities = 39/168 (23%), Positives = 68/168 (40%), Gaps = 6/168 (3%)
Query: 457 DLKDAQKSIPIGTILAILTTSFVY-LSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW 515
++ DA+K++P ++I +FVY +N+ F A +L G ++G SW
Sbjct: 257 EMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSW 316
Query: 516 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLT 575
P + + +F G L RL + A++ +P L H + + P ALL+
Sbjct: 317 VMPVSVALSTFGGING----YLFTYSRLCFSGAREGHLPSLLAMIHVR-HCTPIPALLVC 371
Query: 576 AAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRP 623
+ +L+ + +S +CY L L R RP
Sbjct: 372 CGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRP 419
>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
sapiens]
Length = 1632
Score = 36.2 bits (82), Expect = 0.18
Identities = 29/124 (23%), Positives = 47/124 (37%), Gaps = 1/124 (0%)
Query: 939 RTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTW 998
RT E+R + S+T+ Q +K+ + +DEDE+ + EK H +
Sbjct: 246 RTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQ 305
Query: 999 TKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMP 1058
KD A R + K E ++ D+ E K AK V+ +
Sbjct: 306 PKD-LAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKT 364
Query: 1059 GPPR 1062
PP+
Sbjct: 365 HPPK 368
>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
sapiens]
Length = 1616
Score = 36.2 bits (82), Expect = 0.18
Identities = 29/124 (23%), Positives = 47/124 (37%), Gaps = 1/124 (0%)
Query: 939 RTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTW 998
RT E+R + S+T+ Q +K+ + +DEDE+ + EK H +
Sbjct: 230 RTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQ 289
Query: 999 TKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMP 1058
KD A R + K E ++ D+ E K AK V+ +
Sbjct: 290 PKD-LAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKT 348
Query: 1059 GPPR 1062
PP+
Sbjct: 349 HPPK 352
>gi|181337167 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 14 [Homo sapiens]
Length = 771
Score = 36.2 bits (82), Expect = 0.18
Identities = 43/188 (22%), Positives = 79/188 (42%), Gaps = 14/188 (7%)
Query: 426 VLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVV 485
VL T F +G + TG A K+ SIP +++ Y+S V
Sbjct: 254 VLQGAATCFYAFIGFDIIATTGEEA--------KNPNTSIPYAITASLVICLTAYVSVSV 305
Query: 486 LFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQ 545
+ + + ++ + V + + +V+ IGS + L SL PR++
Sbjct: 306 ILTLMVPYYTIDT---ESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIY 362
Query: 546 AIAKDNIIPFLRVFGHSKANGE-PTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYL 604
A+A D ++ R H + E P A +++ +A L L+ SL + ++S+ L+ Y
Sbjct: 363 AMAGDGLL--FRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYT 420
Query: 605 FVNLACAL 612
V++ L
Sbjct: 421 LVSVCVLL 428
>gi|114326550 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 3 [Homo sapiens]
Length = 619
Score = 35.4 bits (80), Expect = 0.30
Identities = 43/191 (22%), Positives = 83/191 (43%), Gaps = 17/191 (8%)
Query: 424 EYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSN 483
E +L T F VG + TG A ++ Q+SIP+G ++++ Y +
Sbjct: 251 EGILRGAATCFYAFVGFDCIATTGEEA--------QNPQRSIPMGIVISLSVCFLAYFAV 302
Query: 484 VVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW-PSPWVIVIGSFFSTCGAGLQSLTGAPR 542
+ L+ + + L +G W P+ +V+ +GS + + L S+ PR
Sbjct: 303 SSALTLMMPYYQLQPE-SPLPEAFLYIG---WAPARYVVAVGSLCALSTSLLGSMFPMPR 358
Query: 543 LLQAIAKDNIIPFLRVFGH-SKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLM 601
++ A+A+D ++ RV P A +++ IA + L + ++S+ L+
Sbjct: 359 VIYAMAEDGLL--FRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLL 416
Query: 602 CYLFVNLACAL 612
Y V++ C L
Sbjct: 417 AYSLVSI-CVL 426
>gi|114326544 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 3 [Homo sapiens]
Length = 619
Score = 35.4 bits (80), Expect = 0.30
Identities = 43/191 (22%), Positives = 83/191 (43%), Gaps = 17/191 (8%)
Query: 424 EYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSN 483
E +L T F VG + TG A ++ Q+SIP+G ++++ Y +
Sbjct: 251 EGILRGAATCFYAFVGFDCIATTGEEA--------QNPQRSIPMGIVISLSVCFLAYFAV 302
Query: 484 VVLFGACIEGVVLRDKFGDAVKGNLVVGTLSW-PSPWVIVIGSFFSTCGAGLQSLTGAPR 542
+ L+ + + L +G W P+ +V+ +GS + + L S+ PR
Sbjct: 303 SSALTLMMPYYQLQPE-SPLPEAFLYIG---WAPARYVVAVGSLCALSTSLLGSMFPMPR 358
Query: 543 LLQAIAKDNIIPFLRVFGH-SKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLM 601
++ A+A+D ++ RV P A +++ IA + L + ++S+ L+
Sbjct: 359 VIYAMAEDGLL--FRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLL 416
Query: 602 CYLFVNLACAL 612
Y V++ C L
Sbjct: 417 AYSLVSI-CVL 426
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,632,237
Number of Sequences: 37866
Number of extensions: 1646138
Number of successful extensions: 4720
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 4618
Number of HSP's gapped (non-prelim): 103
length of query: 1099
length of database: 18,247,518
effective HSP length: 113
effective length of query: 986
effective length of database: 13,968,660
effective search space: 13773098760
effective search space used: 13773098760
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.