Guide to the Human Genome
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Search of human proteins with 13375846

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13375846 2-oxoglutarate and iron-dependent oxygenase domain
containing 2 [Homo sapiens]
         (290 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13375846 2-oxoglutarate and iron-dependent oxygenase domain c...   592   e-169
gi|32307144 lysyl hydroxylase 1 precursor [Homo sapiens]               57   2e-08
gi|4505891 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 pr...    46   3e-05
gi|62739166 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 i...    44   1e-04
gi|33636742 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 i...    44   1e-04
gi|44955929 calmodulin regulated spectrin-associated protein 1-l...    33   0.29 
gi|45827701 pad-1-like [Homo sapiens]                                  30   2.5  
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap...    30   3.2  
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]    30   3.2  
gi|224922791 amidohydrolase domain containing 2 isoform 2 [Homo ...    29   5.5  
gi|21361513 amidohydrolase domain containing 2 isoform 1 [Homo s...    29   5.5  
gi|239740995 PREDICTED: hypothetical protein XP_002342058 [Homo ...    28   7.2  
gi|88900493 zinc finger, DHHC domain containing 19 [Homo sapiens]      28   7.2  
gi|73695475 protein BAP28 [Homo sapiens]                               28   7.2  
gi|239743072 PREDICTED: hypothetical protein [Homo sapiens]            28   9.4  
gi|239508718 PREDICTED: hypothetical protein [Homo sapiens]            28   9.4  

>gi|13375846 2-oxoglutarate and iron-dependent oxygenase domain
           containing 2 [Homo sapiens]
          Length = 290

 Score =  592 bits (1526), Expect = e-169
 Identities = 290/290 (100%), Positives = 290/290 (100%)

Query: 1   MVELEQEVERRQRLGQESAARKALIASSYHPARPEVYDSLQDAALAPEFLAVTEYSVSPD 60
           MVELEQEVERRQRLGQESAARKALIASSYHPARPEVYDSLQDAALAPEFLAVTEYSVSPD
Sbjct: 1   MVELEQEVERRQRLGQESAARKALIASSYHPARPEVYDSLQDAALAPEFLAVTEYSVSPD 60

Query: 61  ADLKGLLQRLETVSEEKRIYRVPVFTAPFCQALLEELEHFEQSDMPKGRPNTMNNYGVLL 120
           ADLKGLLQRLETVSEEKRIYRVPVFTAPFCQALLEELEHFEQSDMPKGRPNTMNNYGVLL
Sbjct: 61  ADLKGLLQRLETVSEEKRIYRVPVFTAPFCQALLEELEHFEQSDMPKGRPNTMNNYGVLL 120

Query: 121 HELGLDEPLMTPLRERFLQPLMALLYPDCGGGRLDSHRAFVVKYAPGQDLELGCHYDNAE 180
           HELGLDEPLMTPLRERFLQPLMALLYPDCGGGRLDSHRAFVVKYAPGQDLELGCHYDNAE
Sbjct: 121 HELGLDEPLMTPLRERFLQPLMALLYPDCGGGRLDSHRAFVVKYAPGQDLELGCHYDNAE 180

Query: 181 LTLNVALGKVFTGGALYFGGLFQAPTALTEPLEVEHVVGQGVLHRGGQLHGARPLGTGER 240
           LTLNVALGKVFTGGALYFGGLFQAPTALTEPLEVEHVVGQGVLHRGGQLHGARPLGTGER
Sbjct: 181 LTLNVALGKVFTGGALYFGGLFQAPTALTEPLEVEHVVGQGVLHRGGQLHGARPLGTGER 240

Query: 241 WNLVVWLRASAVRNSLCPMCCREPDLVDDEGFGDGFTREEPATVDVCALT 290
           WNLVVWLRASAVRNSLCPMCCREPDLVDDEGFGDGFTREEPATVDVCALT
Sbjct: 241 WNLVVWLRASAVRNSLCPMCCREPDLVDDEGFGDGFTREEPATVDVCALT 290


>gi|32307144 lysyl hydroxylase 1 precursor [Homo sapiens]
          Length = 727

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 39/129 (30%), Positives = 62/129 (48%), Gaps = 12/129 (9%)

Query: 79  IYRVPVFTAPFCQALLEELEHFEQSDMPKGRPNTMN-------NYGVLLHELGLDEPLMT 131
           +Y  P+FT   C  L+EE+EHF Q  +   + N +           + ++++G +     
Sbjct: 555 VYWFPIFTEVACDELVEEMEHFGQWSLGNNKDNRIQGGYENVPTIDIHMNQIGFEREWHK 614

Query: 132 PLRERFLQPLMALLYPDCGGGRLDSHRAFVVKYAPGQDLELGCHYDNAELTLNVALGKVF 191
            L E ++ P+   LYP     R     AFVV+Y P +   L  H+D +  T+N+AL +V 
Sbjct: 615 FLLE-YIAPMTEKLYPGY-YTRAQFDLAFVVRYKPDEQPSLMPHHDASTFTINIALNRV- 671

Query: 192 TGGALYFGG 200
             G  Y GG
Sbjct: 672 --GVDYEGG 678


>gi|4505891 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
           precursor [Homo sapiens]
          Length = 738

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 48/182 (26%), Positives = 80/182 (43%), Gaps = 30/182 (16%)

Query: 79  IYRVPVFTAPFCQALLEELEHF--------EQSDMPKGRPNTMNNYGVLLHELGLDEPLM 130
           +Y  P+ +   C  L+ E+EH+        E S +  G  N +    + + ++G ++  +
Sbjct: 566 VYWFPLLSEQMCDELVAEMEHYGQWSGGRHEDSRLAGGYEN-VPTVDIHMKQVGYEDQWL 624

Query: 131 TPLRERFLQPLMALLYPDCGGGRLDSHRA---FVVKYAPGQDLELGCHYDNAELTLNVAL 187
             LR  ++ P+   L+P    G     RA   FVV+Y P +   L  H+D++  TLNVAL
Sbjct: 625 QLLRT-YVGPMTESLFP----GYHTKARAVMNFVVRYRPDEQPSLRPHHDSSTFTLNVAL 679

Query: 188 ---GKVFTGGALYFGGLFQAPTALTEPLEVEHVVGQGVLHRG--GQLHGARPLGTGERWN 242
              G  + GG   F    +    ++ P +     G  +LH G     H   P   G R+ 
Sbjct: 680 NHKGLDYEGGGCRF---LRYDCVISSPRK-----GWALLHPGRLTHYHEGLPTTWGTRYI 731

Query: 243 LV 244
           +V
Sbjct: 732 MV 733


>gi|62739166 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
           isoform b precursor [Homo sapiens]
          Length = 737

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 47/185 (25%), Positives = 83/185 (44%), Gaps = 30/185 (16%)

Query: 79  IYRVPVFTAPFCQALLEELEHF--------EQSDMPKGRPNTMNNYGVLLHELGLDEPLM 130
           ++  P+F+   C  L+EE+EH+          S +  G  N   +  + + ++ L+   +
Sbjct: 565 VFWFPIFSEKACDELVEEMEHYGKWSGGKHHDSRISGGYENVPTD-DIHMKQVDLENVWL 623

Query: 131 TPLRERFLQPLMALL---YPDCGGGRLDSHRAFVVKYAPGQDLELGCHYDNAELTLNVAL 187
             +RE F+ P+   +   Y   G   L+    FVVKY+P +   L  H+D +  T+N+AL
Sbjct: 624 HFIRE-FIAPVTLKVFAGYYTKGFALLN----FVVKYSPERQRSLRPHHDASTFTINIAL 678

Query: 188 ---GKVFTGGALYFGGLFQAPTALTEPLEVEHVVGQGVLHRG--GQLHGARPLGTGERWN 242
              G+ F GG   F    +   ++  P +     G   +H G    LH   P+  G R+ 
Sbjct: 679 NNVGEDFQGGGCKF---LRYNCSIESPRK-----GWSFMHPGRLTHLHEGLPVKNGTRYI 730

Query: 243 LVVWL 247
            V ++
Sbjct: 731 AVSFI 735


>gi|33636742 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
           isoform a precursor [Homo sapiens]
          Length = 758

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 47/185 (25%), Positives = 83/185 (44%), Gaps = 30/185 (16%)

Query: 79  IYRVPVFTAPFCQALLEELEHF--------EQSDMPKGRPNTMNNYGVLLHELGLDEPLM 130
           ++  P+F+   C  L+EE+EH+          S +  G  N   +  + + ++ L+   +
Sbjct: 586 VFWFPIFSEKACDELVEEMEHYGKWSGGKHHDSRISGGYENVPTD-DIHMKQVDLENVWL 644

Query: 131 TPLRERFLQPLMALL---YPDCGGGRLDSHRAFVVKYAPGQDLELGCHYDNAELTLNVAL 187
             +RE F+ P+   +   Y   G   L+    FVVKY+P +   L  H+D +  T+N+AL
Sbjct: 645 HFIRE-FIAPVTLKVFAGYYTKGFALLN----FVVKYSPERQRSLRPHHDASTFTINIAL 699

Query: 188 ---GKVFTGGALYFGGLFQAPTALTEPLEVEHVVGQGVLHRG--GQLHGARPLGTGERWN 242
              G+ F GG   F    +   ++  P +     G   +H G    LH   P+  G R+ 
Sbjct: 700 NNVGEDFQGGGCKF---LRYNCSIESPRK-----GWSFMHPGRLTHLHEGLPVKNGTRYI 751

Query: 243 LVVWL 247
            V ++
Sbjct: 752 AVSFI 756


>gi|44955929 calmodulin regulated spectrin-associated protein 1-like
           1 [Homo sapiens]
          Length = 1478

 Score = 33.1 bits (74), Expect = 0.29
 Identities = 31/127 (24%), Positives = 54/127 (42%), Gaps = 6/127 (4%)

Query: 1   MVELEQEVERRQRL----GQESAARKALIASSYHPARPEVYDSLQDAALAPEFLAVTEYS 56
           ++E EQ+++    +    GQ++  RK        P  P V + L+D        A+  + 
Sbjct: 195 IMEQEQKLKEHHTVEAPGGQKARYRKEQTLLKQLPCIPLVENLLKDGTDGCALAALIHFY 254

Query: 57  VSPDADLKGLLQRLETVSEEKRIYRVPVFTAPFCQALLEELEHFEQSDMPKGRPNTMNNY 116
                 L+ +  + ET+S    +Y + +    FCQ  L +  HF   DM     +  +NY
Sbjct: 255 CPDVVRLEDICLK-ETMSLADSLYNLQLIQE-FCQEYLNQCCHFTLEDMLYAASSIKSNY 312

Query: 117 GVLLHEL 123
            V + EL
Sbjct: 313 LVFMAEL 319


>gi|45827701 pad-1-like [Homo sapiens]
          Length = 2298

 Score = 30.0 bits (66), Expect = 2.5
 Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 11/93 (11%)

Query: 116 YGVLLHELGLDEPLMTPLRERFLQPLMALLYPDCGGGRLDSHRAFVVKYAPG--QDLELG 173
           + +L H      P++  L E++  PL  LL P        S +AF+V   PG  +  E+ 
Sbjct: 111 FPLLAHAAVSVRPVLLTLYEKYFLPLQKLLLP--------SLQAFIVGLLPGLEEGSEIS 162

Query: 174 CHYDNAELTLNVALGKVFTGGALYFGGLFQAPT 206
              D   L L++ +GK     AL+ G +  +P+
Sbjct: 163 DRTDALLLRLSLVVGKEVFYTALW-GSVLASPS 194


>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
           sapiens]
          Length = 1116

 Score = 29.6 bits (65), Expect = 3.2
 Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 2/76 (2%)

Query: 2   VELEQEVERRQRLGQESAARKALIASSYHPARPEVYDSLQDAALAPEFLAVTEYSVSPDA 61
           +E+  E ++ + L  ES  +KA  A+    A PE+ D +Q   L  E     + S    A
Sbjct: 699 LEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQH--LEREITRYKDESSKAQA 756

Query: 62  DLKGLLQRLETVSEEK 77
           ++  LL+ L+ V  EK
Sbjct: 757 EVDRLLEILKEVENEK 772


>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
          Length = 1088

 Score = 29.6 bits (65), Expect = 3.2
 Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 2/76 (2%)

Query: 2   VELEQEVERRQRLGQESAARKALIASSYHPARPEVYDSLQDAALAPEFLAVTEYSVSPDA 61
           +E+  E ++ + L  ES  +KA  A+    A PE+ D +Q   L  E     + S    A
Sbjct: 671 LEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQH--LEREITRYKDESSKAQA 728

Query: 62  DLKGLLQRLETVSEEK 77
           ++  LL+ L+ V  EK
Sbjct: 729 EVDRLLEILKEVENEK 744


>gi|224922791 amidohydrolase domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 594

 Score = 28.9 bits (63), Expect = 5.5
 Identities = 29/93 (31%), Positives = 40/93 (43%), Gaps = 14/93 (15%)

Query: 148 DCGGGRLDSHRAFVVKYAPGQ-DLEL--GCHYDNAELTLNVALGKVFTGGALYFGGLFQ- 203
           DCGG  L          APG  D+++  G   D ++ T +V  G       +   G+   
Sbjct: 57  DCGGRIL----------APGFIDVQINGGFGVDFSQATEDVGSGVALVARRILSHGVTSF 106

Query: 204 APTALTEPLEVEHVVGQGVLHRGGQLHGARPLG 236
            PT +T P EV H V   +  + G  HGA  LG
Sbjct: 107 CPTLVTSPPEVYHKVVPQIPVKSGGPHGAGVLG 139


>gi|21361513 amidohydrolase domain containing 2 isoform 1 [Homo
           sapiens]
          Length = 439

 Score = 28.9 bits (63), Expect = 5.5
 Identities = 29/93 (31%), Positives = 40/93 (43%), Gaps = 14/93 (15%)

Query: 148 DCGGGRLDSHRAFVVKYAPGQ-DLEL--GCHYDNAELTLNVALGKVFTGGALYFGGLFQ- 203
           DCGG  L          APG  D+++  G   D ++ T +V  G       +   G+   
Sbjct: 57  DCGGRIL----------APGFIDVQINGGFGVDFSQATEDVGSGVALVARRILSHGVTSF 106

Query: 204 APTALTEPLEVEHVVGQGVLHRGGQLHGARPLG 236
            PT +T P EV H V   +  + G  HGA  LG
Sbjct: 107 CPTLVTSPPEVYHKVVPQIPVKSGGPHGAGVLG 139


>gi|239740995 PREDICTED: hypothetical protein XP_002342058 [Homo
           sapiens]
          Length = 361

 Score = 28.5 bits (62), Expect = 7.2
 Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 11  RQRLGQESAARKALIASSYHPARPEVYDSLQDAALAPEFLAVTEYS 56
           R+R G+  A +   ++S  HPARP V  S++  AL  E  A T  S
Sbjct: 128 RRRPGRSLATQNCQLSSRLHPARPPV-GSVRSCALLEEPAAPTASS 172


>gi|88900493 zinc finger, DHHC domain containing 19 [Homo sapiens]
          Length = 309

 Score = 28.5 bits (62), Expect = 7.2
 Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 7/41 (17%)

Query: 221 GVLHRGGQLHGARPLGTGERWNLVVWLRASAVRNSLCPMCC 261
           G+LH+G    G  PL        VVW+   A R   CP CC
Sbjct: 85  GILHQGSAEQG--PLTVH-----VVWVNHGAFRLQWCPKCC 118


>gi|73695475 protein BAP28 [Homo sapiens]
          Length = 2144

 Score = 28.5 bits (62), Expect = 7.2
 Identities = 32/138 (23%), Positives = 54/138 (39%), Gaps = 13/138 (9%)

Query: 12   QRLGQESAARKALIASSYHPARPEVYDSLQDAALAPEFLAV---TEYSVSPDADLKGLLQ 68
            +R  +++    AL+  +   +  E     Q  +L P  L     T   VS +  L   L 
Sbjct: 1703 ERKEEKNVLGSALLCIAEVTSTLEALAIPQLPSLMPSLLTTMKNTSELVSSEVYLLSALA 1762

Query: 69   RLETVSEEKRIYRVPVFTAPFCQALLEELEHFEQSDMPKGRPNTMNNYGVLLHELGLDEP 128
             L+ V E      +P F +P+ + +L ++ H E+     G  +  N     +    L + 
Sbjct: 1763 ALQKVVET-----LPHFISPYLEGILSQVIHLEKITSEMGSASQAN-----IRLTSLKKT 1812

Query: 129  LMTPLRERFLQPLMALLY 146
            L T L  R L P +   Y
Sbjct: 1813 LATTLAPRVLLPAIKKTY 1830


>gi|239743072 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 837

 Score = 28.1 bits (61), Expect = 9.4
 Identities = 17/43 (39%), Positives = 19/43 (44%)

Query: 224 HRGGQLHGARPLGTGERWNLVVWLRASAVRNSLCPMCCREPDL 266
           H GG L GA   G+GE        R S  R+S  P  CR   L
Sbjct: 614 HEGGPLGGAGGGGSGEGQGRGPGSRVSVRRSSRAPSSCRAASL 656


>gi|239508718 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 837

 Score = 28.1 bits (61), Expect = 9.4
 Identities = 17/43 (39%), Positives = 19/43 (44%)

Query: 224 HRGGQLHGARPLGTGERWNLVVWLRASAVRNSLCPMCCREPDL 266
           H GG L GA   G+GE        R S  R+S  P  CR   L
Sbjct: 614 HEGGPLGGAGGGGSGEGQGRGPGSRVSVRRSSRAPSSCRAASL 656


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,109,068
Number of Sequences: 37866
Number of extensions: 573179
Number of successful extensions: 1061
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1047
Number of HSP's gapped (non-prelim): 20
length of query: 290
length of database: 18,247,518
effective HSP length: 101
effective length of query: 189
effective length of database: 14,423,052
effective search space: 2725956828
effective search space used: 2725956828
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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