Search of human proteins with 13375785

Search of human proteins with 13375785

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13375785 steroid 5 alpha-reductase 3 [Homo sapiens]
         (318 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13375785 steroid 5 alpha-reductase 3 [Homo sapiens]                665   0.0  
gi|39812447 3-oxo-5 alpha-steroid 4-dehydrogenase 2 [Homo sapiens]     61   1e-09
gi|4507201 steroid-5-alpha-reductase 1 [Homo sapiens]                  50   2e-06
gi|58332438 steroid 5 alpha-reductase 2-like 2 [Homo sapiens]          34   0.15 
gi|239751670 PREDICTED: similar to hCG16318 [Homo sapiens]             33   0.44 
gi|24475816 glycoprotein, synaptic 2 [Homo sapiens]                    33   0.44 
gi|169163053 PREDICTED: hypothetical protein, partial [Homo sapi...    32   0.75 
gi|190358477 MPV17 mitochondrial membrane protein-like isoform 1...    30   2.2  
gi|7706117 solute carrier family 15, member 3 [Homo sapiens]           30   2.2  
gi|224465231 solute carrier family 9, member 11 [Homo sapiens]         30   2.2  
gi|239755619 PREDICTED: hypothetical protein [Homo sapiens]            29   4.8  
gi|239750132 PREDICTED: hypothetical protein XP_002347267 [Homo ...    29   4.8  
gi|239744440 PREDICTED: hypothetical protein XP_002343124 [Homo ...    29   4.8  
gi|239742426 PREDICTED: hypothetical protein XP_002342512, parti...    29   6.3  
gi|56090548 insulin-like growth factor binding protein-like 1 [H...    29   6.3  
gi|37595752 lamin B receptor [Homo sapiens]                            28   8.2  
gi|37595750 lamin B receptor [Homo sapiens]                            28   8.2  
gi|109150412 hypothetical protein LOC85019 [Homo sapiens]              28   8.2  

>gi|13375785 steroid 5 alpha-reductase 3 [Homo sapiens]
          Length = 318

 Score =  665 bits (1715), Expect = 0.0
 Identities = 318/318 (100%), Positives = 318/318 (100%)

Query: 1   MAPWAEAEHSALNPLRAVWLTLTAAFLLTLLLQLLPPGLLPGCAIFQDLIRYGKTKCGEP 60
           MAPWAEAEHSALNPLRAVWLTLTAAFLLTLLLQLLPPGLLPGCAIFQDLIRYGKTKCGEP
Sbjct: 1   MAPWAEAEHSALNPLRAVWLTLTAAFLLTLLLQLLPPGLLPGCAIFQDLIRYGKTKCGEP 60

Query: 61  SRPAACRAFDVPKRYFSHFYIISVLWNGFLLWCLTQSLFLGAPFPSWLHGLLRILGAAQF 120
           SRPAACRAFDVPKRYFSHFYIISVLWNGFLLWCLTQSLFLGAPFPSWLHGLLRILGAAQF
Sbjct: 61  SRPAACRAFDVPKRYFSHFYIISVLWNGFLLWCLTQSLFLGAPFPSWLHGLLRILGAAQF 120

Query: 121 QGGELALSAFLVLVFLWLHSLRRLFECLYVSVFSNVMIHVVQYCFGLVYYVLVGLTVLSQ 180
           QGGELALSAFLVLVFLWLHSLRRLFECLYVSVFSNVMIHVVQYCFGLVYYVLVGLTVLSQ
Sbjct: 121 QGGELALSAFLVLVFLWLHSLRRLFECLYVSVFSNVMIHVVQYCFGLVYYVLVGLTVLSQ 180

Query: 181 VPMDGRNAYITGKNLLMQARWFHILGMMMFIWSSAHQYKCHVILGNLRKNKAGVVIHCNH 240
           VPMDGRNAYITGKNLLMQARWFHILGMMMFIWSSAHQYKCHVILGNLRKNKAGVVIHCNH
Sbjct: 181 VPMDGRNAYITGKNLLMQARWFHILGMMMFIWSSAHQYKCHVILGNLRKNKAGVVIHCNH 240

Query: 241 RIPFGDWFEYVSSPNYLAELMIYVSMAVTFGFHNLTWWLVVTNVFFNQALSAFLSHQFYK 300
           RIPFGDWFEYVSSPNYLAELMIYVSMAVTFGFHNLTWWLVVTNVFFNQALSAFLSHQFYK
Sbjct: 241 RIPFGDWFEYVSSPNYLAELMIYVSMAVTFGFHNLTWWLVVTNVFFNQALSAFLSHQFYK 300

Query: 301 SKFVSYPKHRKAFLPFLF 318
           SKFVSYPKHRKAFLPFLF
Sbjct: 301 SKFVSYPKHRKAFLPFLF 318


>gi|39812447 3-oxo-5 alpha-steroid 4-dehydrogenase 2 [Homo sapiens]
          Length = 254

 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 42/118 (35%), Positives = 57/118 (48%), Gaps = 15/118 (12%)

Query: 205 LGMMMFIWSSAHQYKCHVILGNLRKNKAGVVIHCNHRIPFGDWFEYVSSPNYLAELMIYV 264
           LG+ +FI           IL  LRK         ++RIP G  F YVS  N+L E++ ++
Sbjct: 148 LGVFLFILGMGINIHSDYILRQLRKPG-----EISYRIPQGGLFTYVSGANFLGEIIEWI 202

Query: 265 SMAVTFGFHNLTWWL-VVTNVFFNQA---LSAFLSHQFYKSKFVSYPKHRKAFLPFLF 318
             A+       TW L  +   FF+     L AF  H+FY   F  YPK RKA +PF+F
Sbjct: 203 GYALA------TWSLPALAFAFFSLCFLGLRAFHHHRFYLKMFEDYPKSRKALIPFIF 254


>gi|4507201 steroid-5-alpha-reductase 1 [Homo sapiens]
          Length = 259

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 37/102 (36%), Positives = 48/102 (47%), Gaps = 19/102 (18%)

Query: 223 ILGNLRKNKAGVVIHCNHRIPFGDWFEYVSSPNYLAELMIYVSMAVTFGFHNLTWWLVVT 282
           IL NLRK          ++IP G  FEYV++ NY  E+M +   A+       +W   V 
Sbjct: 171 ILRNLRKPG-----DTGYKIPRGGLFEYVTAANYFGEIMEWCGYALA------SW--SVQ 217

Query: 283 NVFFNQALSAFLS------HQFYKSKFVSYPKHRKAFLPFLF 318
              F      FLS      H++Y  KF  YPK RK  +PFLF
Sbjct: 218 GAAFAFFTFCFLSGRAKEHHEWYLRKFEEYPKFRKIIIPFLF 259


>gi|58332438 steroid 5 alpha-reductase 2-like 2 [Homo sapiens]
          Length = 363

 Score = 34.3 bits (77), Expect = 0.15
 Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 2/75 (2%)

Query: 243 PFGDWFEYVSSPNYLAELMIYVSMAVTFGFHNLTWWLVVTNVFFNQALSAFLSHQFYKSK 302
           PF   F  VS PNY  E+  ++S  V      L   +    +    +L A   H+ Y  K
Sbjct: 290 PFTWMFFLVSCPNYTYEIGSWISFTVM--TQTLPVGIFTLLMSIQMSLWAQKKHKIYLRK 347

Query: 303 FVSYPKHRKAFLPFL 317
           F SY   + A +PF+
Sbjct: 348 FNSYIHRKSAMIPFI 362


>gi|239751670 PREDICTED: similar to hCG16318 [Homo sapiens]
          Length = 166

 Score = 32.7 bits (73), Expect = 0.44
 Identities = 29/114 (25%), Positives = 48/114 (42%), Gaps = 3/114 (2%)

Query: 205 LGMMMFIWSSAHQYKCHVILGNLRKNKAGV-VIHCNHRIPFGDWFEYVSSPNYLAELMIY 263
           L + +F+      +  H+ L +LR   +    I    + PF   F  VS PNY  E+  +
Sbjct: 54  LALAIFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSW 113

Query: 264 VSMAVTFGFHNLTWWLVVTNVFFNQALSAFLSHQFYKSKFVSYPKHRKAFLPFL 317
           +  A+      +  + +V   F    + A   H+ Y  +F  YP  R   +PFL
Sbjct: 114 IGFAIMTQCLPVALFSLVG--FTQMTIWAKGKHRSYLKEFRDYPPLRMPIIPFL 165


>gi|24475816 glycoprotein, synaptic 2 [Homo sapiens]
          Length = 308

 Score = 32.7 bits (73), Expect = 0.44
 Identities = 29/114 (25%), Positives = 48/114 (42%), Gaps = 3/114 (2%)

Query: 205 LGMMMFIWSSAHQYKCHVILGNLRKNKAGV-VIHCNHRIPFGDWFEYVSSPNYLAELMIY 263
           L + +F+      +  H+ L +LR   +    I    + PF   F  VS PNY  E+  +
Sbjct: 196 LALAIFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSW 255

Query: 264 VSMAVTFGFHNLTWWLVVTNVFFNQALSAFLSHQFYKSKFVSYPKHRKAFLPFL 317
           +  A+      +  + +V   F    + A   H+ Y  +F  YP  R   +PFL
Sbjct: 256 IGFAIMTQCLPVALFSLVG--FTQMTIWAKGKHRSYLKEFRDYPPLRMPIIPFL 307


>gi|169163053 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 300

 Score = 32.0 bits (71), Expect = 0.75
 Identities = 11/43 (25%), Positives = 27/43 (62%), Gaps = 1/43 (2%)

Query: 132 VLVFLWLHSLRRLFECLYVSVFSNVMIHVVQY-CFGLVYYVLV 173
           V V++++H    ++ C+Y+ +++++ IH+  Y C  +  YV +
Sbjct: 47  VYVYIYIHIYMYMYICIYMCIYTHICIHICIYMCIYIHIYVYI 89


>gi|190358477 MPV17 mitochondrial membrane protein-like isoform 1
           [Homo sapiens]
          Length = 196

 Score = 30.4 bits (67), Expect = 2.2
 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 8/81 (9%)

Query: 109 HGLLRILGAAQFQGGELALSAFLVLVFLWLHSLRRLFECLYVSVFSNVMIHVVQYCFGLV 168
           H LL  L   Q  G  +A+SAF V + + L     +F  L    ++        Y  GL+
Sbjct: 80  HALLAKLLCDQVVGAPIAVSAFYVGMSI-LQGKDDIFLDLKQKFWNT-------YLSGLM 131

Query: 169 YYVLVGLTVLSQVPMDGRNAY 189
           Y+  V LT  S VP+  R AY
Sbjct: 132 YWPFVQLTNFSLVPVQWRTAY 152


>gi|7706117 solute carrier family 15, member 3 [Homo sapiens]
          Length = 581

 Score = 30.4 bits (67), Expect = 2.2
 Identities = 51/172 (29%), Positives = 70/172 (40%), Gaps = 26/172 (15%)

Query: 15  LRAVWLTLTAAFLLTLLLQLLPPGLLPGCAIFQDLIRYGKTK-CGE-PSRP--AACRAFD 70
           L  V+L    A  L+LLL L   GLLP  A F D    G++  CGE P+ P   AC +  
Sbjct: 93  LADVYLGRYRAVALSLLLYLAASGLLPATA-FPD----GRSSFCGEMPASPLGPACPSAG 147

Query: 71  VPKRYFSHFYIISVLWNGFLLWCLTQSLFLGAPFPSWLHGLLRILGAAQFQG-GELALSA 129
            P+   S  Y   VL+ G LL  L  S          +   L   GA Q    G  A   
Sbjct: 148 CPRSSPSP-YCAPVLYAGLLLLGLAASS---------VRSNLTSFGADQVMDLGRDATRR 197

Query: 130 FLVLVFLWLHSLRRLFECLYVSVFSNVMIHVVQY-----CFGLVYYVLVGLT 176
           F    F W  +L  +   L V+     +  ++ Y     C GL +++ +  T
Sbjct: 198 FFNW-FYWSINLGAVLSLLVVAFIQQNISFLLGYSIPVGCVGLAFFIFLFAT 248


>gi|224465231 solute carrier family 9, member 11 [Homo sapiens]
          Length = 1124

 Score = 30.4 bits (67), Expect = 2.2
 Identities = 32/152 (21%), Positives = 66/152 (43%), Gaps = 24/152 (15%)

Query: 143 RLFECLYVSVFSNVMIHVVQYCFGLVYYVLVGLTVLSQVPMDGRNAY----ITGKNLLMQ 198
           ++ +C+   VFSN++ +++  CF +VY       ++  + M G  A     +   +L  +
Sbjct: 237 KIIQCILADVFSNMLTNII-LCFSMVYMTFY---IVEFLGMSGTLALAAVGLNLDSLTFK 292

Query: 199 ARWFHILGMMMFIWSSAHQYKCHVILGNLRKNKAGVVIHCN-------HRIPF-GDWFEY 250
            +   ++   + I+SS +++  +           G+VI C        H IPF    F  
Sbjct: 293 PKIELVITKFLRIFSSVYEHLIYAFF--------GIVIGCGELSHYEFHTIPFIFILFTT 344

Query: 251 VSSPNYLAELMIYVSMAVTFGFHNLTWWLVVT 282
           V+    L  L++   +  +   +N  W +V+T
Sbjct: 345 VNLVRLLTILLVSPILMHSNYEYNWRWGVVIT 376


>gi|239755619 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 261

 Score = 29.3 bits (64), Expect = 4.8
 Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 7/48 (14%)

Query: 82  ISVLWNGFLLWCLTQSLFLGAPFPSWLHGLLRILGAAQFQGGELALSA 129
           + VL    LLW   Q+L +G P  S + G+L++ G     GGE+A+ A
Sbjct: 85  LEVLLGVLLLW---QALHIGHPVQSQVVGVLQVAG----DGGEIAIGA 125


>gi|239750132 PREDICTED: hypothetical protein XP_002347267 [Homo
           sapiens]
          Length = 261

 Score = 29.3 bits (64), Expect = 4.8
 Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 7/48 (14%)

Query: 82  ISVLWNGFLLWCLTQSLFLGAPFPSWLHGLLRILGAAQFQGGELALSA 129
           + VL    LLW   Q+L +G P  S + G+L++ G     GGE+A+ A
Sbjct: 85  LEVLLGVLLLW---QALHIGHPVQSQVVGVLQVAG----DGGEIAIGA 125


>gi|239744440 PREDICTED: hypothetical protein XP_002343124 [Homo
           sapiens]
          Length = 261

 Score = 29.3 bits (64), Expect = 4.8
 Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 7/48 (14%)

Query: 82  ISVLWNGFLLWCLTQSLFLGAPFPSWLHGLLRILGAAQFQGGELALSA 129
           + VL    LLW   Q+L +G P  S + G+L++ G     GGE+A+ A
Sbjct: 85  LEVLLGVLLLW---QALHIGHPVQSQVVGVLQVAG----DGGEIAIGA 125


>gi|239742426 PREDICTED: hypothetical protein XP_002342512, partial
           [Homo sapiens]
          Length = 201

 Score = 28.9 bits (63), Expect = 6.3
 Identities = 10/36 (27%), Positives = 24/36 (66%)

Query: 134 VFLWLHSLRRLFECLYVSVFSNVMIHVVQYCFGLVY 169
           V+++L++   ++ C+YV +++ V ++V  Y +  VY
Sbjct: 21  VYMYLYTHMCIYTCVYVCIYTCVCVYVCIYVYMCVY 56


>gi|56090548 insulin-like growth factor binding protein-like 1
          [Homo sapiens]
          Length = 278

 Score = 28.9 bits (63), Expect = 6.3
 Identities = 22/49 (44%), Positives = 25/49 (51%), Gaps = 4/49 (8%)

Query: 20 LTLTAAFLLTLLLQLLPPGLLPGCAIFQDLIRYGKTKCGEPSRPAACRA 68
          L+L    LL LLL LLPP L P   I    +   + KCG P RP  C A
Sbjct: 4  LSLLLPLLLLLLLPLLPP-LSPSLGIRD--VGGRRPKCG-PCRPEGCPA 48


>gi|37595752 lamin B receptor [Homo sapiens]
          Length = 615

 Score = 28.5 bits (62), Expect = 8.2
 Identities = 11/44 (25%), Positives = 27/44 (61%), Gaps = 2/44 (4%)

Query: 247 WFEYVSSPNYLAELMIYVSMAVTFGFHNLTWWLVVTNVFFNQAL 290
           W+ +V  PNYL +L++ ++ ++  GF+++  +  +  ++F   L
Sbjct: 539 WWGFVRHPNYLGDLIMALAWSLPCGFNHILPYFYI--IYFTMLL 580


>gi|37595750 lamin B receptor [Homo sapiens]
          Length = 615

 Score = 28.5 bits (62), Expect = 8.2
 Identities = 11/44 (25%), Positives = 27/44 (61%), Gaps = 2/44 (4%)

Query: 247 WFEYVSSPNYLAELMIYVSMAVTFGFHNLTWWLVVTNVFFNQAL 290
           W+ +V  PNYL +L++ ++ ++  GF+++  +  +  ++F   L
Sbjct: 539 WWGFVRHPNYLGDLIMALAWSLPCGFNHILPYFYI--IYFTMLL 580


>gi|109150412 hypothetical protein LOC85019 [Homo sapiens]
          Length = 296

 Score = 28.5 bits (62), Expect = 8.2
 Identities = 18/68 (26%), Positives = 26/68 (38%), Gaps = 2/68 (2%)

Query: 107 WLHGLLRILGAAQFQGGELALSAFLVLVFLWLHSLRRLFECLYVSVFSNVMIHVVQYCFG 166
           WL   +  +G      G  ALS   + VFL LH++  +  C Y   F        + C  
Sbjct: 72  WLPASVLFVGI--IYAGSRALSRLAIPVFLTLHNVAEVIICGYQKCFQKEKTSPAKICSA 129

Query: 167 LVYYVLVG 174
           L+     G
Sbjct: 130 LLLLAAAG 137


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.332    0.143    0.485 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,099,011
Number of Sequences: 37866
Number of extensions: 515858
Number of successful extensions: 1379
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1366
Number of HSP's gapped (non-prelim): 21
length of query: 318
length of database: 18,247,518
effective HSP length: 102
effective length of query: 216
effective length of database: 14,385,186
effective search space: 3107200176
effective search space used: 3107200176
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.