Guide to the Human Genome
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Search of human proteins with 4809279

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4809279 annexin VII isoform 2 [Homo sapiens]
         (488 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4809279 annexin VII isoform 2 [Homo sapiens]                      1001   0.0  
gi|4502111 annexin VII isoform 1 [Homo sapiens]                       945   0.0  
gi|4557317 annexin A11 [Homo sapiens]                                 427   e-119
gi|22165433 annexin A11 [Homo sapiens]                                427   e-119
gi|22165431 annexin A11 [Homo sapiens]                                427   e-119
gi|4502105 annexin IV [Homo sapiens]                                  314   1e-85
gi|51896029 annexin A13 isoform b [Homo sapiens]                      311   9e-85
gi|51895795 annexin A13 isoform a [Homo sapiens]                      311   9e-85
gi|71773415 annexin VI isoform 2 [Homo sapiens]                       308   7e-84
gi|91807122 annexin A8L2 [Homo sapiens]                               308   7e-84
gi|91823262 annexin A8 [Homo sapiens]                                 307   2e-83
gi|149588958 annexin A8-like 1 [Homo sapiens]                         305   5e-83
gi|4502107 annexin 5 [Homo sapiens]                                   305   8e-83
gi|71773329 annexin VI isoform 1 [Homo sapiens]                       301   7e-82
gi|4826643 annexin A3 [Homo sapiens]                                  286   4e-77
gi|4502101 annexin I [Homo sapiens]                                   278   8e-75
gi|4757756 annexin A2 isoform 2 [Homo sapiens]                        263   3e-70
gi|50845386 annexin A2 isoform 2 [Homo sapiens]                       263   3e-70
gi|50845388 annexin A2 isoform 1 [Homo sapiens]                       263   3e-70
gi|209862831 annexin A2 isoform 2 [Homo sapiens]                      263   3e-70
gi|48762937 annexin A10 [Homo sapiens]                                233   4e-61
gi|145864465 annexin A9 [Homo sapiens]                                178   9e-45
gi|239752501 PREDICTED: hypothetical protein XP_002347094 [Homo ...   102   8e-22
gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho...    74   3e-13
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    72   1e-12
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...    72   1e-12
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...    72   1e-12
gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens]            71   2e-12
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     71   3e-12
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      70   4e-12

>gi|4809279 annexin VII isoform 2 [Homo sapiens]
          Length = 488

 Score = 1001 bits (2588), Expect = 0.0
 Identities = 488/488 (100%), Positives = 488/488 (100%)

Query: 1   MSYPGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGY 60
           MSYPGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGY
Sbjct: 1   MSYPGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGY 60

Query: 61  PAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQV 120
           PAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQV
Sbjct: 61  PAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQV 120

Query: 121 PLPGGFPGGQMPSQYPGGQPTYPSQINTDSFSSYPVFSPVSLDYSSEPATVTQVTQGTIR 180
           PLPGGFPGGQMPSQYPGGQPTYPSQINTDSFSSYPVFSPVSLDYSSEPATVTQVTQGTIR
Sbjct: 121 PLPGGFPGGQMPSQYPGGQPTYPSQINTDSFSSYPVFSPVSLDYSSEPATVTQVTQGTIR 180

Query: 181 PAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLK 240
           PAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLK
Sbjct: 181 PAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLK 240

Query: 241 SELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQ 300
           SELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQ
Sbjct: 241 SELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQ 300

Query: 301 SEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLGTD 360
           SEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLGTD
Sbjct: 301 SEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLGTD 360

Query: 361 ESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAF 420
           ESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAF
Sbjct: 361 ESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAF 420

Query: 421 FAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRR 480
           FAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRR
Sbjct: 421 FAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRR 480

Query: 481 LLLAIVGQ 488
           LLLAIVGQ
Sbjct: 481 LLLAIVGQ 488


>gi|4502111 annexin VII isoform 1 [Homo sapiens]
          Length = 466

 Score =  945 bits (2443), Expect = 0.0
 Identities = 466/488 (95%), Positives = 466/488 (95%), Gaps = 22/488 (4%)

Query: 1   MSYPGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGY 60
           MSYPGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGY
Sbjct: 1   MSYPGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGY 60

Query: 61  PAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQV 120
           PAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQV
Sbjct: 61  PAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQV 120

Query: 121 PLPGGFPGGQMPSQYPGGQPTYPSQINTDSFSSYPVFSPVSLDYSSEPATVTQVTQGTIR 180
           PLPGGFPGGQMPSQYPGGQPTYPSQ                      PATVTQVTQGTIR
Sbjct: 121 PLPGGFPGGQMPSQYPGGQPTYPSQ----------------------PATVTQVTQGTIR 158

Query: 181 PAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLK 240
           PAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLK
Sbjct: 159 PAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLK 218

Query: 241 SELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQ 300
           SELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQ
Sbjct: 219 SELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQ 278

Query: 301 SEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLGTD 360
           SEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLGTD
Sbjct: 279 SEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLGTD 338

Query: 361 ESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAF 420
           ESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAF
Sbjct: 339 ESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAF 398

Query: 421 FAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRR 480
           FAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRR
Sbjct: 399 FAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRR 458

Query: 481 LLLAIVGQ 488
           LLLAIVGQ
Sbjct: 459 LLLAIVGQ 466


>gi|4557317 annexin A11 [Homo sapiens]
          Length = 505

 Score =  427 bits (1098), Expect = e-119
 Identities = 248/513 (48%), Positives = 309/513 (60%), Gaps = 37/513 (7%)

Query: 1   MSYPGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMG-------GGAYPQVPSSG 53
           MSYPGYPP    P  GYPPA           YP P   PP+G        G + Q   SG
Sbjct: 1   MSYPGYPP----PPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSG 56

Query: 54  YPGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAG----FSGYPQPP 109
              A      GG   P  YPGAP  G    YP VPPG GFG PP        +  YP P 
Sbjct: 57  M-AANMSGTFGGANMPNLYPGAPGAG----YPPVPPG-GFGQPPSAQQPVPPYGMYPPPG 110

Query: 110 SQSYGGGPAQVPLPGGF--------PGGQMPSQYPG-------GQPTYPSQINTDSFSSY 154
                  P+  P PG          PG Q P  YPG       GQP  P         SY
Sbjct: 111 GNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSY 170

Query: 155 PVFSPVSLDYSSEPATVTQVTQGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVAN 214
           P +        + P T    ++GTI  A  FD +RDAE+LRKAMKGFGTDEQAI+D + +
Sbjct: 171 PGYPGSGTVTPAVPPTQFG-SRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGS 229

Query: 215 RSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAG 274
           RSN QRQ+I  +FKT+YGKDLIKDLKSELSGN E+ ILAL   P  +D + +++A++G G
Sbjct: 230 RSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVG 289

Query: 275 TQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDEN 334
           T E  LIEIL +R+N+ IRE+ R Y++EF + LE+ IRSDTSGHF+RLL+S+ QGNRDE+
Sbjct: 290 TDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDES 349

Query: 335 QSINHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSS 394
            +++  +AQ DAQ LY AGE RLGTDES FN +L +RS   L A    Y RM  RD+  S
Sbjct: 350 TNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKS 409

Query: 395 VSREFSGYVESGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQI 454
           + RE SG +E G+  +++C  N PAFFAERL  AM+GAGT D TL+RI+V+RSE DL+ I
Sbjct: 410 ICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDI 469

Query: 455 KQMFAQMYQKTLGTMIAGDTSGDYRRLLLAIVG 487
           +  + +MY K+L   I+GDTSGDYR++LL I G
Sbjct: 470 RSEYKRMYGKSLYHDISGDTSGDYRKILLKICG 502



 Score = 86.3 bits (212), Expect = 6e-17
 Identities = 56/165 (33%), Positives = 93/165 (56%), Gaps = 9/165 (5%)

Query: 174 VTQGTIRPAANFD---AIRDAEILRKAMKG-FGTDEQAIVDVVANRSNDQRQKIKAAFKT 229
           ++QG    + N D   A RDA+ L  A +   GTDE     V+ +RS      +   ++ 
Sbjct: 341 LSQGNRDESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQR 400

Query: 230 SYGKDLIKDLKSELSGNMEELILALFM----PPTYYDAWSLRKAMQGAGTQERVLIEILC 285
             G+D+ K +  E+SG++EE +LA+       P ++ A  L KAM+GAGT++R LI I+ 
Sbjct: 401 MTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFF-AERLNKAMRGAGTKDRTLIRIMV 459

Query: 286 TRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGN 330
           +R+  ++ +I   Y+  +G+ L  DI  DTSG + ++L+ +C GN
Sbjct: 460 SRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICGGN 504


>gi|22165433 annexin A11 [Homo sapiens]
          Length = 505

 Score =  427 bits (1098), Expect = e-119
 Identities = 248/513 (48%), Positives = 309/513 (60%), Gaps = 37/513 (7%)

Query: 1   MSYPGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMG-------GGAYPQVPSSG 53
           MSYPGYPP    P  GYPPA           YP P   PP+G        G + Q   SG
Sbjct: 1   MSYPGYPP----PPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSG 56

Query: 54  YPGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAG----FSGYPQPP 109
              A      GG   P  YPGAP  G    YP VPPG GFG PP        +  YP P 
Sbjct: 57  M-AANMSGTFGGANMPNLYPGAPGAG----YPPVPPG-GFGQPPSAQQPVPPYGMYPPPG 110

Query: 110 SQSYGGGPAQVPLPGGF--------PGGQMPSQYPG-------GQPTYPSQINTDSFSSY 154
                  P+  P PG          PG Q P  YPG       GQP  P         SY
Sbjct: 111 GNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSY 170

Query: 155 PVFSPVSLDYSSEPATVTQVTQGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVAN 214
           P +        + P T    ++GTI  A  FD +RDAE+LRKAMKGFGTDEQAI+D + +
Sbjct: 171 PGYPGSGTVTPAVPPTQFG-SRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGS 229

Query: 215 RSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAG 274
           RSN QRQ+I  +FKT+YGKDLIKDLKSELSGN E+ ILAL   P  +D + +++A++G G
Sbjct: 230 RSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVG 289

Query: 275 TQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDEN 334
           T E  LIEIL +R+N+ IRE+ R Y++EF + LE+ IRSDTSGHF+RLL+S+ QGNRDE+
Sbjct: 290 TDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDES 349

Query: 335 QSINHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSS 394
            +++  +AQ DAQ LY AGE RLGTDES FN +L +RS   L A    Y RM  RD+  S
Sbjct: 350 TNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKS 409

Query: 395 VSREFSGYVESGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQI 454
           + RE SG +E G+  +++C  N PAFFAERL  AM+GAGT D TL+RI+V+RSE DL+ I
Sbjct: 410 ICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDI 469

Query: 455 KQMFAQMYQKTLGTMIAGDTSGDYRRLLLAIVG 487
           +  + +MY K+L   I+GDTSGDYR++LL I G
Sbjct: 470 RSEYKRMYGKSLYHDISGDTSGDYRKILLKICG 502



 Score = 86.3 bits (212), Expect = 6e-17
 Identities = 56/165 (33%), Positives = 93/165 (56%), Gaps = 9/165 (5%)

Query: 174 VTQGTIRPAANFD---AIRDAEILRKAMKG-FGTDEQAIVDVVANRSNDQRQKIKAAFKT 229
           ++QG    + N D   A RDA+ L  A +   GTDE     V+ +RS      +   ++ 
Sbjct: 341 LSQGNRDESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQR 400

Query: 230 SYGKDLIKDLKSELSGNMEELILALFM----PPTYYDAWSLRKAMQGAGTQERVLIEILC 285
             G+D+ K +  E+SG++EE +LA+       P ++ A  L KAM+GAGT++R LI I+ 
Sbjct: 401 MTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFF-AERLNKAMRGAGTKDRTLIRIMV 459

Query: 286 TRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGN 330
           +R+  ++ +I   Y+  +G+ L  DI  DTSG + ++L+ +C GN
Sbjct: 460 SRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICGGN 504


>gi|22165431 annexin A11 [Homo sapiens]
          Length = 505

 Score =  427 bits (1098), Expect = e-119
 Identities = 248/513 (48%), Positives = 309/513 (60%), Gaps = 37/513 (7%)

Query: 1   MSYPGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMG-------GGAYPQVPSSG 53
           MSYPGYPP    P  GYPPA           YP P   PP+G        G + Q   SG
Sbjct: 1   MSYPGYPP----PPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSG 56

Query: 54  YPGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAG----FSGYPQPP 109
              A      GG   P  YPGAP  G    YP VPPG GFG PP        +  YP P 
Sbjct: 57  M-AANMSGTFGGANMPNLYPGAPGAG----YPPVPPG-GFGQPPSAQQPVPPYGMYPPPG 110

Query: 110 SQSYGGGPAQVPLPGGF--------PGGQMPSQYPG-------GQPTYPSQINTDSFSSY 154
                  P+  P PG          PG Q P  YPG       GQP  P         SY
Sbjct: 111 GNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSY 170

Query: 155 PVFSPVSLDYSSEPATVTQVTQGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVAN 214
           P +        + P T    ++GTI  A  FD +RDAE+LRKAMKGFGTDEQAI+D + +
Sbjct: 171 PGYPGSGTVTPAVPPTQFG-SRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGS 229

Query: 215 RSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAG 274
           RSN QRQ+I  +FKT+YGKDLIKDLKSELSGN E+ ILAL   P  +D + +++A++G G
Sbjct: 230 RSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVG 289

Query: 275 TQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDEN 334
           T E  LIEIL +R+N+ IRE+ R Y++EF + LE+ IRSDTSGHF+RLL+S+ QGNRDE+
Sbjct: 290 TDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDES 349

Query: 335 QSINHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSS 394
            +++  +AQ DAQ LY AGE RLGTDES FN +L +RS   L A    Y RM  RD+  S
Sbjct: 350 TNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKS 409

Query: 395 VSREFSGYVESGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQI 454
           + RE SG +E G+  +++C  N PAFFAERL  AM+GAGT D TL+RI+V+RSE DL+ I
Sbjct: 410 ICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDI 469

Query: 455 KQMFAQMYQKTLGTMIAGDTSGDYRRLLLAIVG 487
           +  + +MY K+L   I+GDTSGDYR++LL I G
Sbjct: 470 RSEYKRMYGKSLYHDISGDTSGDYRKILLKICG 502



 Score = 86.3 bits (212), Expect = 6e-17
 Identities = 56/165 (33%), Positives = 93/165 (56%), Gaps = 9/165 (5%)

Query: 174 VTQGTIRPAANFD---AIRDAEILRKAMKG-FGTDEQAIVDVVANRSNDQRQKIKAAFKT 229
           ++QG    + N D   A RDA+ L  A +   GTDE     V+ +RS      +   ++ 
Sbjct: 341 LSQGNRDESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQR 400

Query: 230 SYGKDLIKDLKSELSGNMEELILALFM----PPTYYDAWSLRKAMQGAGTQERVLIEILC 285
             G+D+ K +  E+SG++EE +LA+       P ++ A  L KAM+GAGT++R LI I+ 
Sbjct: 401 MTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFF-AERLNKAMRGAGTKDRTLIRIMV 459

Query: 286 TRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGN 330
           +R+  ++ +I   Y+  +G+ L  DI  DTSG + ++L+ +C GN
Sbjct: 460 SRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICGGN 504


>gi|4502105 annexin IV [Homo sapiens]
          Length = 321

 Score =  314 bits (804), Expect = 1e-85
 Identities = 155/311 (49%), Positives = 222/311 (71%)

Query: 177 GTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLI 236
           GT++ A+ F+A+ DA+ LRKAMKG GTDE AI+ V+A R+  QRQ+I+ A+K++ G+DLI
Sbjct: 8   GTVKAASGFNAMEDAQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKSTIGRDLI 67

Query: 237 KDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIV 296
            DLKSELSGN E++I+ +  P   YD   LR+AM+GAGT E  LIEIL +RT +EIR I 
Sbjct: 68  DDLKSELSGNFEQVIVGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRIS 127

Query: 297 RCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGR 356
           + YQ ++GR LE DIRSDTS  F+R+LVS+  G RDE   ++  + ++DAQ LY+AGE +
Sbjct: 128 QTYQQQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDEGNYLDDALVRQDAQDLYEAGEKK 187

Query: 357 LGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALN 416
            GTDE  F  +L +R+   L    + Y R++ +D+  S+  E SG  E  L  I++C  N
Sbjct: 188 WGTDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMRN 247

Query: 417 RPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSG 476
           + A+FAE+LY +MKG GTDD+TL+R++V+R+EID++ I+  F ++Y K+L + I GDTSG
Sbjct: 248 KSAYFAEKLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRAHFKRLYGKSLYSFIKGDTSG 307

Query: 477 DYRRLLLAIVG 487
           DYR++LL + G
Sbjct: 308 DYRKVLLVLCG 318



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 44/146 (30%), Positives = 83/146 (56%), Gaps = 4/146 (2%)

Query: 189 RDAEILRKA-MKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNM 247
           +DA+ L +A  K +GTDE   + V+ +R+ +    +   +K    KD+ + +KSE SG+ 
Sbjct: 175 QDAQDLYEAGEKKWGTDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSF 234

Query: 248 EELILAL---FMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFG 304
           E+ +LA+       + Y A  L K+M+G GT +  LI ++ +R   ++ +I   ++  +G
Sbjct: 235 EDALLAIVKCMRNKSAYFAEKLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRAHFKRLYG 294

Query: 305 RDLEKDIRSDTSGHFERLLVSMCQGN 330
           + L   I+ DTSG + ++L+ +C G+
Sbjct: 295 KSLYSFIKGDTSGDYRKVLLVLCGGD 320


>gi|51896029 annexin A13 isoform b [Homo sapiens]
          Length = 357

 Score =  311 bits (797), Expect = 9e-85
 Identities = 155/302 (51%), Positives = 217/302 (71%)

Query: 185 FDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELS 244
           FD  RDA+ L KA KG GT+E AI+++++ R++D+RQ+IK  +K +YGK+L + LKSELS
Sbjct: 55  FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 114

Query: 245 GNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFG 304
           GN E+  LAL   P+ Y A  L+KAM+G GT E VLIE+LCTRTN+EI  I   YQ  F 
Sbjct: 115 GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 174

Query: 305 RDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLGTDESCF 364
           R LE D++ DTSG+ +++LVS+ Q NR+E   ++  +A +DA+ LY AGEGR GTDE  F
Sbjct: 175 RSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAF 234

Query: 365 NMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAER 424
           N +LA RS+ QLRAT +AY  +  +D+  ++  E SG ++    T+++CA +   +FAER
Sbjct: 235 NEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAER 294

Query: 425 LYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRRLLLA 484
           LY +MKGAGTD+ TL+RIVVTR+E+DL  IK  F + YQK+L  M+  DTSGD+R+LL+A
Sbjct: 295 LYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVA 354

Query: 485 IV 486
           ++
Sbjct: 355 LL 356


>gi|51895795 annexin A13 isoform a [Homo sapiens]
          Length = 316

 Score =  311 bits (797), Expect = 9e-85
 Identities = 155/302 (51%), Positives = 217/302 (71%)

Query: 185 FDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELS 244
           FD  RDA+ L KA KG GT+E AI+++++ R++D+RQ+IK  +K +YGK+L + LKSELS
Sbjct: 14  FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 73

Query: 245 GNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFG 304
           GN E+  LAL   P+ Y A  L+KAM+G GT E VLIE+LCTRTN+EI  I   YQ  F 
Sbjct: 74  GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 133

Query: 305 RDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLGTDESCF 364
           R LE D++ DTSG+ +++LVS+ Q NR+E   ++  +A +DA+ LY AGEGR GTDE  F
Sbjct: 134 RSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAF 193

Query: 365 NMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAER 424
           N +LA RS+ QLRAT +AY  +  +D+  ++  E SG ++    T+++CA +   +FAER
Sbjct: 194 NEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAER 253

Query: 425 LYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRRLLLA 484
           LY +MKGAGTD+ TL+RIVVTR+E+DL  IK  F + YQK+L  M+  DTSGD+R+LL+A
Sbjct: 254 LYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVA 313

Query: 485 IV 486
           ++
Sbjct: 314 LL 315


>gi|71773415 annexin VI isoform 2 [Homo sapiens]
          Length = 667

 Score =  308 bits (789), Expect = 7e-84
 Identities = 155/312 (49%), Positives = 215/312 (68%), Gaps = 1/312 (0%)

Query: 176 QGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDL 235
           +GT+RPA +F+   DA+ LRKAMKG GTDE  I+D++ +RSN QRQ+I+  FK+ +G+DL
Sbjct: 354 KGTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDL 413

Query: 236 IKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREI 295
           + DLKSE+SG++  LIL L MPP +YDA  L+KAM+GAGT E+ LIEIL TRTN EIR I
Sbjct: 414 MTDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAI 473

Query: 296 VRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEG 355
              Y+ ++ + LE  + SDTSGHF R+L+S+  G+R+E    N   A+EDAQ +     G
Sbjct: 474 NEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGE-NLDQAREDAQEIADTPSG 532

Query: 356 RLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCAL 415
              + E+ F  IL TRS+P LR   + + +M N D+  ++ +E SG V      I+Q   
Sbjct: 533 DKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVK 592

Query: 416 NRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTS 475
           N+P FFA++LY +MKGAGTD+ TL RI+V+RSEIDL+ I++ F + Y K+L   I GDTS
Sbjct: 593 NKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTS 652

Query: 476 GDYRRLLLAIVG 487
           GD+ + LLA+ G
Sbjct: 653 GDFLKALLALCG 664



 Score =  292 bits (747), Expect = 5e-79
 Identities = 142/312 (45%), Positives = 214/312 (68%)

Query: 176 QGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDL 235
           +G+I     FD  +DAE L  AMKGFG+D++AI+D++ +RSN QRQ++  ++K+ YGKDL
Sbjct: 11  RGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDL 70

Query: 236 IKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREI 295
           I DLK EL+G  E LI+ L  PP Y DA  ++ A+ G GT E+ LIEIL +RTN+++ ++
Sbjct: 71  IADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQL 130

Query: 296 VRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEG 355
           V  Y+  + RDLE DI  DTSGHF+++LV + QG R+E+  ++  + Q+D Q LY+AGE 
Sbjct: 131 VAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGEL 190

Query: 356 RLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCAL 415
           + GTDE+ F  IL  RS   LR   + Y +   + + +S+  E SG  E  +  +++C  
Sbjct: 191 KWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIR 250

Query: 416 NRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTS 475
           + P +FAERL+ AMKG GT D+TL+RI+V+RSE+D++ I+++F   Y+K+L +MI  DTS
Sbjct: 251 STPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310

Query: 476 GDYRRLLLAIVG 487
           G+Y++ LL + G
Sbjct: 311 GEYKKTLLKLSG 322



 Score =  132 bits (331), Expect = 9e-31
 Identities = 90/318 (28%), Positives = 165/318 (51%), Gaps = 38/318 (11%)

Query: 201 FGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFM---- 256
           +GTDE   + ++ NRS    + +   +  + GK +   ++ ELSG+ E+L+LA+      
Sbjct: 192 WGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRS 251

Query: 257 PPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTS 316
            P Y+ A  L KAM+G GT++  LI I+ +R+  ++ +I   +++++ + L   I++DTS
Sbjct: 252 TPEYF-AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310

Query: 317 GHFERLLVSMCQGNRD-------ENQSINHQM----------------------AQEDAQ 347
           G +++ L+ +  G+ D       E   + +QM                         DA+
Sbjct: 311 GEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNPDADAK 370

Query: 348 RLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGL 407
            L +A +G LGTDE     I+  RS  Q +   + +     RDL++ +  E SG +    
Sbjct: 371 ALRKAMKG-LGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDL---A 426

Query: 408 KTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLG 467
           + IL   +    + A++L  AM+GAGTD+  L+ I+ TR+  ++  I + + + Y K+L 
Sbjct: 427 RLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSLE 486

Query: 468 TMIAGDTSGDYRRLLLAI 485
             ++ DTSG +RR+L+++
Sbjct: 487 DALSSDTSGHFRRILISL 504



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 42/152 (27%), Positives = 77/152 (50%), Gaps = 7/152 (4%)

Query: 184 NFDAIR-DAEILRKAMKGFGTD-EQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKS 241
           N D  R DA+ +     G  T  E   + ++  RS    +++   F      D+   +K 
Sbjct: 515 NLDQAREDAQEIADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKK 574

Query: 242 ELSGNMEELILALFMP----PTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVR 297
           E+SG++ +  +A+       P ++ A  L K+M+GAGT E+ L  I+ +R+  ++  I R
Sbjct: 575 EMSGDVRDAFVAIVQSVKNKPLFF-ADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRR 633

Query: 298 CYQSEFGRDLEKDIRSDTSGHFERLLVSMCQG 329
            +  ++ + L + I  DTSG F + L+++C G
Sbjct: 634 EFIEKYDKSLHQAIEGDTSGDFLKALLALCGG 665


>gi|91807122 annexin A8L2 [Homo sapiens]
          Length = 327

 Score =  308 bits (789), Expect = 7e-84
 Identities = 160/311 (51%), Positives = 218/311 (70%), Gaps = 1/311 (0%)

Query: 178 TIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIK 237
           T++ +++F+   DAE L KAMKG GT+EQAI+DV+  RSN QRQ+I  +FK  +GKDL +
Sbjct: 14  TVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTE 73

Query: 238 DLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVR 297
            LKSELSG  E LI+AL  PP  Y+A  L  AM+G GT+E V+IEIL +RT  ++REI++
Sbjct: 74  TLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMK 133

Query: 298 CYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQS-INHQMAQEDAQRLYQAGEGR 356
            Y+ ++G  LE+DI++DTSG+ ER+LV + QG+RD+  S ++  +A +DAQ LY AGE  
Sbjct: 134 AYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPALALQDAQDLYAAGENI 193

Query: 357 LGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALN 416
            GTDE  F  IL TRS   L    E Y ++AN+ +  S+  E  G +E  + T+++C  N
Sbjct: 194 RGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQN 253

Query: 417 RPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSG 476
             ++FAERLYYAMKGAGT D TL+R +V+RSEIDL  IK  F +MY KTL +MI  DTSG
Sbjct: 254 LHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIMEDTSG 313

Query: 477 DYRRLLLAIVG 487
           DY+  LL++VG
Sbjct: 314 DYKNALLSLVG 324



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 25/88 (28%), Positives = 45/88 (51%)

Query: 399 FSGYVESGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMF 458
           +  ++E    T+   +   P   AE LY AMKG GT++  ++ ++  RS     QI + F
Sbjct: 4   WKAWIEQEGVTVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSF 63

Query: 459 AQMYQKTLGTMIAGDTSGDYRRLLLAIV 486
              + K L   +  + SG + RL++A++
Sbjct: 64  KAQFGKDLTETLKSELSGKFERLIVALM 91


>gi|91823262 annexin A8 [Homo sapiens]
          Length = 327

 Score =  307 bits (786), Expect = 2e-83
 Identities = 160/311 (51%), Positives = 218/311 (70%), Gaps = 1/311 (0%)

Query: 178 TIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIK 237
           T++ +++F+   DAE L KAMKG GT+EQAI+DV+  RSN QRQ+I  +FK  +GKDL +
Sbjct: 14  TVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTE 73

Query: 238 DLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVR 297
            LKSELSG  E LI+AL  PP  Y+A  L  AM+G GT+E V+IEIL +RT  ++REI++
Sbjct: 74  TLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMK 133

Query: 298 CYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQS-INHQMAQEDAQRLYQAGEGR 356
            Y+ ++G  LE+DI++DTSG+ ER+LV + QG+RD+  S ++  +A +DAQ LY AGE  
Sbjct: 134 AYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPGLALQDAQDLYAAGEKI 193

Query: 357 LGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALN 416
            GTDE  F  IL TRS   L    E Y ++AN+ +  S+  E  G +E  + T+++C  N
Sbjct: 194 RGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQN 253

Query: 417 RPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSG 476
             ++FAERLYYAMKGAGT D TL+R +V+RSEIDL  IK  F +MY KTL +MI  DTSG
Sbjct: 254 LHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIMEDTSG 313

Query: 477 DYRRLLLAIVG 487
           DY+  LL++VG
Sbjct: 314 DYKNALLSLVG 324



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 25/88 (28%), Positives = 45/88 (51%)

Query: 399 FSGYVESGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMF 458
           +  ++E    T+   +   P   AE LY AMKG GT++  ++ ++  RS     QI + F
Sbjct: 4   WKSWIEQEGVTVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSF 63

Query: 459 AQMYQKTLGTMIAGDTSGDYRRLLLAIV 486
              + K L   +  + SG + RL++A++
Sbjct: 64  KAQFGKDLTETLKSELSGKFERLIVALM 91


>gi|149588958 annexin A8-like 1 [Homo sapiens]
          Length = 327

 Score =  305 bits (782), Expect = 5e-83
 Identities = 159/311 (51%), Positives = 218/311 (70%), Gaps = 1/311 (0%)

Query: 178 TIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIK 237
           T++ +++F+   DAE L +AMKG GT+EQAI+DV+  RSN QRQ+I  +FK  +GKDL +
Sbjct: 14  TVKSSSHFNPDPDAETLYQAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTE 73

Query: 238 DLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVR 297
            LKSELSG  E LI+AL  PP  Y+A  L  AM+G GT+E V+IEIL +RT  ++REI++
Sbjct: 74  TLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMK 133

Query: 298 CYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQS-INHQMAQEDAQRLYQAGEGR 356
            Y+ ++G  LE+DI++DTSG+ ER+LV + QG+RD+  S ++  +A +DAQ LY AGE  
Sbjct: 134 AYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPGLALQDAQDLYAAGEKI 193

Query: 357 LGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALN 416
            GTDE  F  IL TRS   L    E Y ++AN+ +  S+  E  G +E  + T+++C  N
Sbjct: 194 RGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQN 253

Query: 417 RPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSG 476
             ++FAERLYYAMKGAGT D TL+R +V+RSEIDL  IK  F +MY KTL +MI  DTSG
Sbjct: 254 LHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIMEDTSG 313

Query: 477 DYRRLLLAIVG 487
           DY+  LL++VG
Sbjct: 314 DYKNALLSLVG 324



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 25/88 (28%), Positives = 45/88 (51%)

Query: 399 FSGYVESGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMF 458
           +  ++E    T+   +   P   AE LY AMKG GT++  ++ ++  RS     QI + F
Sbjct: 4   WKSWIEQEGVTVKSSSHFNPDPDAETLYQAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSF 63

Query: 459 AQMYQKTLGTMIAGDTSGDYRRLLLAIV 486
              + K L   +  + SG + RL++A++
Sbjct: 64  KAQFGKDLTETLKSELSGKFERLIVALM 91


>gi|4502107 annexin 5 [Homo sapiens]
          Length = 320

 Score =  305 bits (780), Expect = 8e-83
 Identities = 153/318 (48%), Positives = 219/318 (68%)

Query: 171 VTQVTQGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTS 230
           + QV +GT+     FD   DAE LRKAMKG GTDE++I+ ++ +RSN QRQ+I AAFKT 
Sbjct: 1   MAQVLRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTL 60

Query: 231 YGKDLIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQ 290
           +G+DL+ DLKSEL+G  E+LI+AL  P   YDA+ L+ A++GAGT E+VL EI+ +RT +
Sbjct: 61  FGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPE 120

Query: 291 EIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLY 350
           E+R I + Y+ E+G  LE D+  DTSG+++R+LV + Q NRD +  I+    ++DAQ L+
Sbjct: 121 ELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALF 180

Query: 351 QAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTI 410
           QAGE + GTDE  F  I  TRS   LR   + Y  ++   +  ++ RE SG +E  L  +
Sbjct: 181 QAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAV 240

Query: 411 LQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMI 470
           ++   + PA+ AE LYYAMKGAGTDD TL+R++V+RSEIDL  I++ F + +  +L +MI
Sbjct: 241 VKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMI 300

Query: 471 AGDTSGDYRRLLLAIVGQ 488
            GDTSGDY++ LL + G+
Sbjct: 301 KGDTSGDYKKALLLLCGE 318


>gi|71773329 annexin VI isoform 1 [Homo sapiens]
          Length = 673

 Score =  301 bits (772), Expect = 7e-82
 Identities = 155/318 (48%), Positives = 215/318 (67%), Gaps = 7/318 (2%)

Query: 176 QGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDL 235
           +GT+RPA +F+   DA+ LRKAMKG GTDE  I+D++ +RSN QRQ+I+  FK+ +G+DL
Sbjct: 354 KGTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDL 413

Query: 236 IKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREI 295
           + DLKSE+SG++  LIL L MPP +YDA  L+KAM+GAGT E+ LIEIL TRTN EIR I
Sbjct: 414 MTDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAI 473

Query: 296 VRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQ------RL 349
              Y+ ++ + LE  + SDTSGHF R+L+S+  G+R+E    N   A+EDAQ       +
Sbjct: 474 NEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGE-NLDQAREDAQVAAEILEI 532

Query: 350 YQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKT 409
                G   + E+ F  IL TRS+P LR   + + +M N D+  ++ +E SG V      
Sbjct: 533 ADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVA 592

Query: 410 ILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTM 469
           I+Q   N+P FFA++LY +MKGAGTD+ TL RI+V+RSEIDL+ I++ F + Y K+L   
Sbjct: 593 IVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQA 652

Query: 470 IAGDTSGDYRRLLLAIVG 487
           I GDTSGD+ + LLA+ G
Sbjct: 653 IEGDTSGDFLKALLALCG 670



 Score =  292 bits (747), Expect = 5e-79
 Identities = 142/312 (45%), Positives = 214/312 (68%)

Query: 176 QGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDL 235
           +G+I     FD  +DAE L  AMKGFG+D++AI+D++ +RSN QRQ++  ++K+ YGKDL
Sbjct: 11  RGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDL 70

Query: 236 IKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREI 295
           I DLK EL+G  E LI+ L  PP Y DA  ++ A+ G GT E+ LIEIL +RTN+++ ++
Sbjct: 71  IADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQL 130

Query: 296 VRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEG 355
           V  Y+  + RDLE DI  DTSGHF+++LV + QG R+E+  ++  + Q+D Q LY+AGE 
Sbjct: 131 VAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGEL 190

Query: 356 RLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCAL 415
           + GTDE+ F  IL  RS   LR   + Y +   + + +S+  E SG  E  +  +++C  
Sbjct: 191 KWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIR 250

Query: 416 NRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTS 475
           + P +FAERL+ AMKG GT D+TL+RI+V+RSE+D++ I+++F   Y+K+L +MI  DTS
Sbjct: 251 STPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310

Query: 476 GDYRRLLLAIVG 487
           G+Y++ LL + G
Sbjct: 311 GEYKKTLLKLSG 322



 Score =  132 bits (331), Expect = 9e-31
 Identities = 90/318 (28%), Positives = 165/318 (51%), Gaps = 38/318 (11%)

Query: 201 FGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFM---- 256
           +GTDE   + ++ NRS    + +   +  + GK +   ++ ELSG+ E+L+LA+      
Sbjct: 192 WGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRS 251

Query: 257 PPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTS 316
            P Y+ A  L KAM+G GT++  LI I+ +R+  ++ +I   +++++ + L   I++DTS
Sbjct: 252 TPEYF-AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310

Query: 317 GHFERLLVSMCQGNRD-------ENQSINHQM----------------------AQEDAQ 347
           G +++ L+ +  G+ D       E   + +QM                         DA+
Sbjct: 311 GEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNPDADAK 370

Query: 348 RLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGL 407
            L +A +G LGTDE     I+  RS  Q +   + +     RDL++ +  E SG +    
Sbjct: 371 ALRKAMKG-LGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDL---A 426

Query: 408 KTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLG 467
           + IL   +    + A++L  AM+GAGTD+  L+ I+ TR+  ++  I + + + Y K+L 
Sbjct: 427 RLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSLE 486

Query: 468 TMIAGDTSGDYRRLLLAI 485
             ++ DTSG +RR+L+++
Sbjct: 487 DALSSDTSGHFRRILISL 504



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 44/154 (28%), Positives = 77/154 (50%), Gaps = 8/154 (5%)

Query: 183 ANFDAIRDAEILRKAMKGFGTD---EQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDL 239
           A  DA   AEIL  A    G     E   + ++  RS    +++   F      D+   +
Sbjct: 519 AREDAQVAAEILEIADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTI 578

Query: 240 KSELSGNMEELILALFMP----PTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREI 295
           K E+SG++ +  +A+       P ++ A  L K+M+GAGT E+ L  I+ +R+  ++  I
Sbjct: 579 KKEMSGDVRDAFVAIVQSVKNKPLFF-ADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNI 637

Query: 296 VRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQG 329
            R +  ++ + L + I  DTSG F + L+++C G
Sbjct: 638 RREFIEKYDKSLHQAIEGDTSGDFLKALLALCGG 671


>gi|4826643 annexin A3 [Homo sapiens]
          Length = 323

 Score =  286 bits (731), Expect = 4e-77
 Identities = 144/312 (46%), Positives = 210/312 (67%)

Query: 176 QGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDL 235
           +GT+R   +F    DAE ++KA++G GTDE+ ++ ++  RSN QRQ I   ++ +YGK+L
Sbjct: 9   RGTVRDYPDFSPSVDAEAIQKAIRGIGTDEKMLISILTERSNAQRQLIVKEYQAAYGKEL 68

Query: 236 IKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREI 295
             DLK +LSG+ E L++AL  PP  +DA  L+K+M+GAGT E  LIEIL TRT++++++I
Sbjct: 69  KDDLKGDLSGHFEHLMVALVTPPAVFDAKQLKKSMKGAGTNEDALIEILTTRTSRQMKDI 128

Query: 296 VRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEG 355
            + Y + + + L  DI S+TSG F + L+++  G RDE+  ++  +A++DAQ LY+AGE 
Sbjct: 129 SQAYYTVYKKSLGDDISSETSGDFRKALLTLADGRRDESLKVDEHLAKQDAQILYKAGEN 188

Query: 356 RLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCAL 415
           R GTDE  F  IL  RSFPQL+ T + Y  ++ +D++ S+  E SG+ E  L  I+ C  
Sbjct: 189 RWGTDEDKFTEILCLRSFPQLKLTFDEYRNISQKDIVDSIKGELSGHFEDLLLAIVNCVR 248

Query: 416 NRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTS 475
           N PAF AERL+ A+KG GTD+ TL RI+V+RSEIDL+ I+  F + Y  +L + I  DTS
Sbjct: 249 NTPAFLAERLHRALKGIGTDEFTLNRIMVSRSEIDLLDIRTEFKKHYGYSLYSAIKSDTS 308

Query: 476 GDYRRLLLAIVG 487
           GDY   LL I G
Sbjct: 309 GDYEITLLKICG 320



 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 49/149 (32%), Positives = 84/149 (56%), Gaps = 6/149 (4%)

Query: 187 AIRDAEILRKAMKG-FGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSG 245
           A +DA+IL KA +  +GTDE    +++  RS  Q +     ++    KD++  +K ELSG
Sbjct: 175 AKQDAQILYKAGENRWGTDEDKFTEILCLRSFPQLKLTFDEYRNISQKDIVDSIKGELSG 234

Query: 246 NMEELILALFM----PPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQS 301
           + E+L+LA+       P +  A  L +A++G GT E  L  I+ +R+  ++ +I   ++ 
Sbjct: 235 HFEDLLLAIVNCVRNTPAFL-AERLHRALKGIGTDEFTLNRIMVSRSEIDLLDIRTEFKK 293

Query: 302 EFGRDLEKDIRSDTSGHFERLLVSMCQGN 330
            +G  L   I+SDTSG +E  L+ +C G+
Sbjct: 294 HYGYSLYSAIKSDTSGDYEITLLKICGGD 322


>gi|4502101 annexin I [Homo sapiens]
          Length = 346

 Score =  278 bits (711), Expect = 8e-75
 Identities = 143/309 (46%), Positives = 200/309 (64%)

Query: 179 IRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKD 238
           + P   F+   D   L KA+   G DE  I+D++  R+N QRQ+IKAA+    GK L + 
Sbjct: 36  VSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDET 95

Query: 239 LKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRC 298
           LK  L+G++EE++LAL   P  +DA  LR AM+G GT E  LIEIL +RTN+EIR+I R 
Sbjct: 96  LKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRV 155

Query: 299 YQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLG 358
           Y+ E  RDL KDI SDTSG F   L+S+ +G+R E+  +N  +A  DA+ LY+AGE R G
Sbjct: 156 YREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRKG 215

Query: 359 TDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRP 418
           TD + FN IL TRS+PQLR   + Y++ +  D+   +  E  G +E  L  I++CA ++P
Sbjct: 216 TDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKP 275

Query: 419 AFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDY 478
           AFFAE+L+ AMKG GT    L+RI+V+RSEID+  IK  + +MY  +L   I  +T GDY
Sbjct: 276 AFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDY 335

Query: 479 RRLLLAIVG 487
            ++L+A+ G
Sbjct: 336 EKILVALCG 344



 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 43/133 (32%), Positives = 74/133 (55%), Gaps = 5/133 (3%)

Query: 202 GTDEQAIVDVVANRSNDQRQKIKAAFKTSYGK-DLIKDLKSELSGNMEELILALFMPPTY 260
           GTD      ++  RS  Q +++   + T Y K D+ K L  EL G++E+ + A+    T 
Sbjct: 215 GTDVNVFNTILTTRSYPQLRRVFQKY-TKYSKHDMNKVLDLELKGDIEKCLTAIVKCATS 273

Query: 261 YDAW---SLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSG 317
             A+    L +AM+G GT+ + LI I+ +R+  ++ +I   YQ  +G  L + I  +T G
Sbjct: 274 KPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKG 333

Query: 318 HFERLLVSMCQGN 330
            +E++LV++C GN
Sbjct: 334 DYEKILVALCGGN 346


>gi|4757756 annexin A2 isoform 2 [Homo sapiens]
          Length = 339

 Score =  263 bits (671), Expect = 3e-70
 Identities = 141/326 (43%), Positives = 208/326 (63%), Gaps = 6/326 (1%)

Query: 163 DYSSEPATVTQVTQGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQK 222
           D+S+ P+       G+++   NFDA RDA  +  A+K  G DE  IV+++ NRSN QRQ 
Sbjct: 16  DHSTPPSAY-----GSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQD 70

Query: 223 IKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIE 282
           I  A++    K+L   LKS LSG++E +IL L   P  YDA  L+ +M+G GT E  LIE
Sbjct: 71  IAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIE 130

Query: 283 ILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQS-INHQM 341
           I+C+RTNQE++EI R Y+  +  DLEKDI SDTSG F +L+V++ +G R E+ S I++++
Sbjct: 131 IICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYEL 190

Query: 342 AQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSG 401
             +DA+ LY AG  R GTD   +  I+  RS P L+   + Y   +  D+L S+ +E  G
Sbjct: 191 IDQDARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKG 250

Query: 402 YVESGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQM 461
            +E+    ++QC  N+P +FA+RLY +MKG GT D  L+RI+V+RSE+D+++I+  F + 
Sbjct: 251 DLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRK 310

Query: 462 YQKTLGTMIAGDTSGDYRRLLLAIVG 487
           Y K+L   I  DT GDY++ LL + G
Sbjct: 311 YGKSLYYYIQQDTKGDYQKALLYLCG 336



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 41/145 (28%), Positives = 80/145 (55%), Gaps = 10/145 (6%)

Query: 190 DAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEE 249
           DA + RK     GTD    + ++  RS    QK+   +K+    D+++ ++ E+ G++E 
Sbjct: 200 DAGVKRK-----GTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLEN 254

Query: 250 LILALFM----PPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGR 305
             L L       P Y+ A  L  +M+G GT+++VLI I+ +R+  ++ +I   ++ ++G+
Sbjct: 255 AFLNLVQCIQNKPLYF-ADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGK 313

Query: 306 DLEKDIRSDTSGHFERLLVSMCQGN 330
            L   I+ DT G +++ L+ +C G+
Sbjct: 314 SLYYYIQQDTKGDYQKALLYLCGGD 338


>gi|50845386 annexin A2 isoform 2 [Homo sapiens]
          Length = 339

 Score =  263 bits (671), Expect = 3e-70
 Identities = 141/326 (43%), Positives = 208/326 (63%), Gaps = 6/326 (1%)

Query: 163 DYSSEPATVTQVTQGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQK 222
           D+S+ P+       G+++   NFDA RDA  +  A+K  G DE  IV+++ NRSN QRQ 
Sbjct: 16  DHSTPPSAY-----GSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQD 70

Query: 223 IKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIE 282
           I  A++    K+L   LKS LSG++E +IL L   P  YDA  L+ +M+G GT E  LIE
Sbjct: 71  IAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIE 130

Query: 283 ILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQS-INHQM 341
           I+C+RTNQE++EI R Y+  +  DLEKDI SDTSG F +L+V++ +G R E+ S I++++
Sbjct: 131 IICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYEL 190

Query: 342 AQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSG 401
             +DA+ LY AG  R GTD   +  I+  RS P L+   + Y   +  D+L S+ +E  G
Sbjct: 191 IDQDARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKG 250

Query: 402 YVESGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQM 461
            +E+    ++QC  N+P +FA+RLY +MKG GT D  L+RI+V+RSE+D+++I+  F + 
Sbjct: 251 DLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRK 310

Query: 462 YQKTLGTMIAGDTSGDYRRLLLAIVG 487
           Y K+L   I  DT GDY++ LL + G
Sbjct: 311 YGKSLYYYIQQDTKGDYQKALLYLCG 336



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 41/145 (28%), Positives = 80/145 (55%), Gaps = 10/145 (6%)

Query: 190 DAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEE 249
           DA + RK     GTD    + ++  RS    QK+   +K+    D+++ ++ E+ G++E 
Sbjct: 200 DAGVKRK-----GTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLEN 254

Query: 250 LILALFM----PPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGR 305
             L L       P Y+ A  L  +M+G GT+++VLI I+ +R+  ++ +I   ++ ++G+
Sbjct: 255 AFLNLVQCIQNKPLYF-ADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGK 313

Query: 306 DLEKDIRSDTSGHFERLLVSMCQGN 330
            L   I+ DT G +++ L+ +C G+
Sbjct: 314 SLYYYIQQDTKGDYQKALLYLCGGD 338


>gi|50845388 annexin A2 isoform 1 [Homo sapiens]
          Length = 357

 Score =  263 bits (671), Expect = 3e-70
 Identities = 141/326 (43%), Positives = 208/326 (63%), Gaps = 6/326 (1%)

Query: 163 DYSSEPATVTQVTQGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQK 222
           D+S+ P+       G+++   NFDA RDA  +  A+K  G DE  IV+++ NRSN QRQ 
Sbjct: 34  DHSTPPSAY-----GSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQD 88

Query: 223 IKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIE 282
           I  A++    K+L   LKS LSG++E +IL L   P  YDA  L+ +M+G GT E  LIE
Sbjct: 89  IAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIE 148

Query: 283 ILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQS-INHQM 341
           I+C+RTNQE++EI R Y+  +  DLEKDI SDTSG F +L+V++ +G R E+ S I++++
Sbjct: 149 IICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYEL 208

Query: 342 AQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSG 401
             +DA+ LY AG  R GTD   +  I+  RS P L+   + Y   +  D+L S+ +E  G
Sbjct: 209 IDQDARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKG 268

Query: 402 YVESGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQM 461
            +E+    ++QC  N+P +FA+RLY +MKG GT D  L+RI+V+RSE+D+++I+  F + 
Sbjct: 269 DLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRK 328

Query: 462 YQKTLGTMIAGDTSGDYRRLLLAIVG 487
           Y K+L   I  DT GDY++ LL + G
Sbjct: 329 YGKSLYYYIQQDTKGDYQKALLYLCG 354



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 41/145 (28%), Positives = 80/145 (55%), Gaps = 10/145 (6%)

Query: 190 DAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEE 249
           DA + RK     GTD    + ++  RS    QK+   +K+    D+++ ++ E+ G++E 
Sbjct: 218 DAGVKRK-----GTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLEN 272

Query: 250 LILALFM----PPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGR 305
             L L       P Y+ A  L  +M+G GT+++VLI I+ +R+  ++ +I   ++ ++G+
Sbjct: 273 AFLNLVQCIQNKPLYF-ADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGK 331

Query: 306 DLEKDIRSDTSGHFERLLVSMCQGN 330
            L   I+ DT G +++ L+ +C G+
Sbjct: 332 SLYYYIQQDTKGDYQKALLYLCGGD 356


>gi|209862831 annexin A2 isoform 2 [Homo sapiens]
          Length = 339

 Score =  263 bits (671), Expect = 3e-70
 Identities = 141/326 (43%), Positives = 208/326 (63%), Gaps = 6/326 (1%)

Query: 163 DYSSEPATVTQVTQGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQK 222
           D+S+ P+       G+++   NFDA RDA  +  A+K  G DE  IV+++ NRSN QRQ 
Sbjct: 16  DHSTPPSAY-----GSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQD 70

Query: 223 IKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIE 282
           I  A++    K+L   LKS LSG++E +IL L   P  YDA  L+ +M+G GT E  LIE
Sbjct: 71  IAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIE 130

Query: 283 ILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQS-INHQM 341
           I+C+RTNQE++EI R Y+  +  DLEKDI SDTSG F +L+V++ +G R E+ S I++++
Sbjct: 131 IICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYEL 190

Query: 342 AQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSG 401
             +DA+ LY AG  R GTD   +  I+  RS P L+   + Y   +  D+L S+ +E  G
Sbjct: 191 IDQDARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKG 250

Query: 402 YVESGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQM 461
            +E+    ++QC  N+P +FA+RLY +MKG GT D  L+RI+V+RSE+D+++I+  F + 
Sbjct: 251 DLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRK 310

Query: 462 YQKTLGTMIAGDTSGDYRRLLLAIVG 487
           Y K+L   I  DT GDY++ LL + G
Sbjct: 311 YGKSLYYYIQQDTKGDYQKALLYLCG 336



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 41/145 (28%), Positives = 80/145 (55%), Gaps = 10/145 (6%)

Query: 190 DAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEE 249
           DA + RK     GTD    + ++  RS    QK+   +K+    D+++ ++ E+ G++E 
Sbjct: 200 DAGVKRK-----GTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLEN 254

Query: 250 LILALFM----PPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGR 305
             L L       P Y+ A  L  +M+G GT+++VLI I+ +R+  ++ +I   ++ ++G+
Sbjct: 255 AFLNLVQCIQNKPLYF-ADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGK 313

Query: 306 DLEKDIRSDTSGHFERLLVSMCQGN 330
            L   I+ DT G +++ L+ +C G+
Sbjct: 314 SLYYYIQQDTKGDYQKALLYLCGGD 338


>gi|48762937 annexin A10 [Homo sapiens]
          Length = 324

 Score =  233 bits (593), Expect = 4e-61
 Identities = 118/310 (38%), Positives = 196/310 (63%), Gaps = 1/310 (0%)

Query: 176 QGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDL 235
           QGTI PA NF+ I DA++L  A++GF  D+  +++++  R N QR  I  A+++ YG+DL
Sbjct: 8   QGTIFPAPNFNPIMDAQMLGGALQGFDCDKDMLINILTQRCNAQRMMIAEAYQSMYGRDL 67

Query: 236 IKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREI 295
           I D++ +LS + ++++  L  PP  YDA  L  AM+G GT E  LIEIL +RTN EI ++
Sbjct: 68  IGDMREQLSDHFKDVMAGLMYPPPLYDAHELWHAMKGVGTDENCLIEILASRTNGEIFQM 127

Query: 296 VRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEG 355
              Y  ++  +L++DI S+TSGHF   L+++ QG R+E  + +  MA +DA  L++A + 
Sbjct: 128 REAYCLQYSNNLQEDIYSETSGHFRDTLMNLVQGTREEGYT-DPAMAAQDAMVLWEACQQ 186

Query: 356 RLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCAL 415
           + G  ++   MIL  +S+ QLR   + +  ++ +D++ +++  + GY +  L  I+ C  
Sbjct: 187 KTGEHKTMLQMILCNKSYQQLRLVFQEFQNISGQDMVDAINECYDGYFQELLVAIVLCVR 246

Query: 416 NRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTS 475
           ++PA+FA RLY A+   G  + T++RI++ RSEIDL+ I++ + + Y K+L   I    S
Sbjct: 247 DKPAYFAYRLYSAIHDFGFHNKTVIRILIARSEIDLLTIRKRYKERYGKSLFHDIRNFAS 306

Query: 476 GDYRRLLLAI 485
           G Y++ LLAI
Sbjct: 307 GHYKKALLAI 316



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 43/171 (25%), Positives = 89/171 (52%), Gaps = 8/171 (4%)

Query: 170 TVTQVTQGTIRPAANFDAI--RDAEILRKA-MKGFGTDEQAIVDVVANRSNDQRQKIKAA 226
           T+  + QGT        A+  +DA +L +A  +  G  +  +  ++ N+S  Q + +   
Sbjct: 154 TLMNLVQGTREEGYTDPAMAAQDAMVLWEACQQKTGEHKTMLQMILCNKSYQQLRLVFQE 213

Query: 227 FKTSYGKDLIKDLKSELSGNMEELILALFM----PPTYYDAWSLRKAMQGAGTQERVLIE 282
           F+   G+D++  +     G  +EL++A+ +     P Y+ A+ L  A+   G   + +I 
Sbjct: 214 FQNISGQDMVDAINECYDGYFQELLVAIVLCVRDKPAYF-AYRLYSAIHDFGFHNKTVIR 272

Query: 283 ILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDE 333
           IL  R+  ++  I + Y+  +G+ L  DIR+  SGH+++ L+++C G+ ++
Sbjct: 273 ILIARSEIDLLTIRKRYKERYGKSLFHDIRNFASGHYKKALLAICAGDAED 323



 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 42/142 (29%), Positives = 71/142 (50%), Gaps = 4/142 (2%)

Query: 345 DAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVE 404
           DAQ L  A +G    D+     IL  R   Q     EAY  M  RDL+  +  + S + +
Sbjct: 22  DAQMLGGALQG-FDCDKDMLINILTQRCNAQRMMIAEAYQSMYGRDLIGDMREQLSDHFK 80

Query: 405 SGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQK 464
             +  ++      P + A  L++AMKG GTD++ L+ I+ +R+  ++ Q+++ +   Y  
Sbjct: 81  DVMAGLMYPP---PLYDAHELWHAMKGVGTDENCLIEILASRTNGEIFQMREAYCLQYSN 137

Query: 465 TLGTMIAGDTSGDYRRLLLAIV 486
            L   I  +TSG +R  L+ +V
Sbjct: 138 NLQEDIYSETSGHFRDTLMNLV 159


>gi|145864465 annexin A9 [Homo sapiens]
          Length = 345

 Score =  178 bits (452), Expect = 9e-45
 Identities = 105/312 (33%), Positives = 173/312 (55%), Gaps = 4/312 (1%)

Query: 175 TQGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKD 234
           T GT+R   NF   +DA+ L +A+ G G D  AIVDV+ NRS +QRQ I   F+    +D
Sbjct: 31  TLGTLRTFLNFSVDKDAQRLLRAITGQGVDRSAIVDVLTNRSREQRQLISRNFQERTQQD 90

Query: 235 LIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIRE 294
           L+K L++ LSGN+E +++AL  P   +DA  LR A++ + +   V IEIL TRT  +++E
Sbjct: 91  LMKSLQAALSGNLERIVMALLQPTAQFDAQELRTALKASDSAVDVAIEILATRTPPQLQE 150

Query: 295 IVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQS-INHQMAQEDAQRLYQAG 353
            +  Y+  F  +   DI S+TSG  + LL+++ +G RD     I++ +A++D Q L Q  
Sbjct: 151 CLAVYKHNFQVEAVDDITSETSGILQDLLLALAKGGRDSYSGIIDYNLAEQDVQAL-QRA 209

Query: 354 EGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQC 413
           EG   + E  +  +   R+   L    + Y R   ++L  +V   F G  +  L  +   
Sbjct: 210 EG--PSREETWVPVFTQRNPEHLIRVFDQYQRSTGQELEEAVQNRFHGDAQVALLGLASV 267

Query: 414 ALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGD 473
             N P +FA++L+ A++    +   L+RI+++R E DL+ I+  F + + K+L + +   
Sbjct: 268 IKNTPLYFADKLHQALQETEPNYQVLIRILISRCETDLLSIRAEFRKKFGKSLYSSLQDA 327

Query: 474 TSGDYRRLLLAI 485
             GD +  LLA+
Sbjct: 328 VKGDCQSALLAL 339



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 29/128 (22%), Positives = 63/128 (49%), Gaps = 5/128 (3%)

Query: 205 EQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFM----PPTY 260
           E+  V V   R+ +   ++   ++ S G++L + +++   G+ +  +L L       P Y
Sbjct: 215 EETWVPVFTQRNPEHLIRVFDQYQRSTGQELEEAVQNRFHGDAQVALLGLASVIKNTPLY 274

Query: 261 YDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFE 320
           + A  L +A+Q      +VLI IL +R   ++  I   ++ +FG+ L   ++    G  +
Sbjct: 275 F-ADKLHQALQETEPNYQVLIRILISRCETDLLSIRAEFRKKFGKSLYSSLQDAVKGDCQ 333

Query: 321 RLLVSMCQ 328
             L+++C+
Sbjct: 334 SALLALCR 341



 Score = 36.2 bits (82), Expect = 0.069
 Identities = 22/80 (27%), Positives = 42/80 (52%), Gaps = 3/80 (3%)

Query: 407 LKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTL 466
           L+T L  ++++ A   +RL  A+ G G D S +V ++  RS      I + F +  Q+ L
Sbjct: 35  LRTFLNFSVDKDA---QRLLRAITGQGVDRSAIVDVLTNRSREQRQLISRNFQERTQQDL 91

Query: 467 GTMIAGDTSGDYRRLLLAIV 486
              +    SG+  R+++A++
Sbjct: 92  MKSLQAALSGNLERIVMALL 111


>gi|239752501 PREDICTED: hypothetical protein XP_002347094 [Homo
           sapiens]
          Length = 112

 Score =  102 bits (254), Expect = 8e-22
 Identities = 53/107 (49%), Positives = 70/107 (65%)

Query: 364 FNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAE 423
           F  IL TRS   L    E Y ++AN+ +  S+  E  G +E  + T+++C  N  ++FAE
Sbjct: 3   FITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAE 62

Query: 424 RLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMI 470
           RLYYAMKGAGT D TL+R +V+RSEIDL  IK  F +MY KTL +MI
Sbjct: 63  RLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMI 109



 Score = 37.4 bits (85), Expect = 0.031
 Identities = 26/106 (24%), Positives = 51/106 (48%), Gaps = 3/106 (2%)

Query: 209 VDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPTY---YDAWS 265
           + ++  RS     ++   ++    K +   +KSE  G++EE +L +         Y A  
Sbjct: 4   ITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAER 63

Query: 266 LRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDI 311
           L  AM+GAGT++  LI  + +R+  ++  I   ++  +G+ L   I
Sbjct: 64  LYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMI 109



 Score = 35.8 bits (81), Expect = 0.090
 Identities = 27/115 (23%), Positives = 52/115 (45%), Gaps = 9/115 (7%)

Query: 281 IEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQ 340
           I ILCTR+   +  +   Y+    + +E  I+S+T G  E  ++++ +  ++ +      
Sbjct: 4   ITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYF--- 60

Query: 341 MAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSV 395
                A+RLY A +G  GT +      + +RS   L      + +M  + L S +
Sbjct: 61  -----AERLYYAMKG-AGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMI 109



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 19/45 (42%), Positives = 24/45 (53%)

Query: 191 AEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDL 235
           AE L  AMKG GT +  ++  + +RS      IK  FK  YGK L
Sbjct: 61  AERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTL 105


>gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo
           sapiens]
          Length = 245

 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 62/175 (35%), Positives = 70/175 (40%), Gaps = 45/175 (25%)

Query: 3   YPGYPPTGYPPFPG--YPPAGQESSFPPSGQYPYPSGFPPMGGGAYP-------QVP--- 50
           YP  PPTG PP P   +PP+G  S  PP G YP P+   P   G YP       ++P   
Sbjct: 72  YPSVPPTGPPPGPPAPFPPSGP-SCPPPGGPYPAPTVPGPGPTGPYPTPNMPFPELPRPY 130

Query: 51  ------------------SSG--YPGAGG-YPAPG-GYPAPGGYPGAPQPGGAPSYPGVP 88
                             SSG   PG GG YP P   YP+PG YP  P P    + P VP
Sbjct: 131 GAPTDPAAAGPLGPWGSMSSGPWAPGMGGQYPTPNMPYPSPGPYPAPPPPQAPGAAPPVP 190

Query: 89  PGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPGGQPTYP 143
            G    VPPG  G       P   Y       P PG +P    P Q P G    P
Sbjct: 191 WGT---VPPGAWG-------PPAPYPAPTGSYPTPGLYPTPSNPFQVPSGPSGAP 235



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 52/159 (32%), Positives = 63/159 (39%), Gaps = 26/159 (16%)

Query: 4   PGYPPTGYP---PF----------PGYPPAGQESSFP----PSGQYPY--PSGFPPMGGG 44
           PG PP G+P   P+           G PP+   S+ P    P+G YP   P+G PP    
Sbjct: 27  PGQPPQGWPGSNPWNNPSAPSSVPSGLPPSATPSTVPFGPAPTGMYPSVPPTGPPPGPPA 86

Query: 45  AYPQVPSSGYPGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSG 104
            +P    S  P  G YPAP     PG  P  P P     +P +P   G    P  AG   
Sbjct: 87  PFPPSGPSCPPPGGPYPAP---TVPGPGPTGPYPTPNMPFPELPRPYGAPTDPAAAG--- 140

Query: 105 YPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPGGQPTYP 143
            P  P  S   GP    + G +P   MP   PG  P  P
Sbjct: 141 -PLGPWGSMSSGPWAPGMGGQYPTPNMPYPSPGPYPAPP 178



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 44/133 (33%), Positives = 47/133 (35%), Gaps = 25/133 (18%)

Query: 15  PGYPPAGQESSFP---PSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPAPGG 71
           PG PP G   S P   PS     PSG PP    A P     G       PAP G      
Sbjct: 27  PGQPPQGWPGSNPWNNPSAPSSVPSGLPP---SATPSTVPFG-------PAPTGM----- 71

Query: 72  YPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPGGFPGGQM 131
           YP  P  G  P  P   P  G   PP G      P P     G GP         P  ++
Sbjct: 72  YPSVPPTGPPPGPPAPFPPSGPSCPPPGG-----PYPAPTVPGPGPTGPYPTPNMPFPEL 126

Query: 132 PSQYPGGQPTYPS 144
           P  Y  G PT P+
Sbjct: 127 PRPY--GAPTDPA 137


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 1691

 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 56/155 (36%), Positives = 61/155 (39%), Gaps = 18/155 (11%)

Query: 8   PTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGG--GAYPQVPSSGYPGAGGYPAPGG 65
           P G P FPG P        P     P P G P   G  G      S G+PG  G P P G
Sbjct: 94  PPGLPGFPGTPGL---PGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPG 150

Query: 66  YPAPGGYPGA------PQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQ 119
            P   G PG+      P P G P YPG P  QG   P G  G  G P PP      GP  
Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210

Query: 120 VPLPGG-------FPGGQMPSQYPGGQPTYPSQIN 147
           +P P G        P G+   Q   G P  P QI+
Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQIS 245



 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 52/146 (35%), Positives = 60/146 (41%), Gaps = 27/146 (18%)

Query: 5   GYPPT-GYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSS----GYPGAGG 59
           G+P   G+P  PG+P  G E    P GQ          G    P  P      G PG  G
Sbjct: 51  GFPGLEGHPGLPGFP--GPEGPPGPRGQ---------KGDDGIPGPPGPKGIRGPPGLPG 99

Query: 60  YPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQ 119
           +P   G P   G+ GAP P G P   G    +GF   PG  GF G   PP      GP  
Sbjct: 100 FPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGF---PGSPGFPGLQGPP------GPPG 150

Query: 120 VPLPGGFPGGQMPSQYPG--GQPTYP 143
           +P   G PG  + S  PG  G P YP
Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYP 176



 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 58/166 (34%), Positives = 65/166 (39%), Gaps = 26/166 (15%)

Query: 4    PGYP-PTGYPPFPGYP----PAGQESSFPPSGQYPYPSGF--PPMGGGAYPQVPSSGYPG 56
            PG P P G P  PG P    P G + +    G +P P G   PP   G   Q  S G PG
Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMG-FPGPQGVEGPPGPSGVPGQPGSPGLPG 1060

Query: 57   AGG--------------YPAPGGYPAPGGYPGAPQPGGA---PSYPGVPPGQGFGVPPGG 99
              G               P P G P   GYPG P   G+   P  PG+P   G    PG 
Sbjct: 1061 QKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGL 1120

Query: 100  AGFSGYPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPGGQPTYPSQ 145
             GF G P PP      GP   P   G PG      +P GQP  P +
Sbjct: 1121 PGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHP-GQPGPPGE 1165



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 59/169 (34%), Positives = 64/169 (37%), Gaps = 45/169 (26%)

Query: 4    PGYPPT-------GYPPFPGYP-PAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPS---- 51
            PG P T       G P FPG P P G +    P G    P    P+GGG +P  P     
Sbjct: 1106 PGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGE 1165

Query: 52   SGYPGAGGYPAPGGY-----------PAP------------GGYPGAPQPGGAPSYPGVP 88
             G PG  G P P G            P P            GG PG P   G P  PG P
Sbjct: 1166 KGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIP---GNPGLPG-P 1221

Query: 89   PGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPG 137
             G+     PG  GF G   PP      GPA +  P G PG Q P   PG
Sbjct: 1222 KGE-----PGFHGFPGVQGPPGPPGSPGPA-LEGPKGNPGPQGPPGRPG 1264



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 52/143 (36%), Positives = 58/143 (40%), Gaps = 26/143 (18%)

Query: 4    PGYP-PTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPA 62
            PG P P G P  PGYP                P     +G    P +P  G PGA G P 
Sbjct: 1076 PGLPGPKGEPGLPGYPGN--------------PGIKGSVGDPGLPGLP--GTPGAKGQPG 1119

Query: 63   PGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPL 122
              G+P   G PG     G P  PG+P   G   P GG G  G P PP +   G P Q  +
Sbjct: 1120 LPGFPGTPGPPGPKGISGPPGNPGLPGEPG---PVGGGGHPGQPGPPGEK--GKPGQDGI 1174

Query: 123  PGGFPGGQM--PSQYPGGQPTYP 143
            PG  P GQ   P Q   G P  P
Sbjct: 1175 PG--PAGQKGEPGQPGFGNPGPP 1195



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 53/155 (34%), Positives = 60/155 (38%), Gaps = 28/155 (18%)

Query: 4   PGYP----PTGYPPFPGYPPAGQE-----SSFPPSGQYPYPSGFPPMGGGAYPQVPSSGY 54
           PG P    P G P F    P G++     +  P     P P G P   G    Q    G 
Sbjct: 611 PGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDP---GQTITQPGKPGL 667

Query: 55  PGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVP--PGQGFGVPPGGAGFSGYPQPPSQS 112
           PG  G     G P   G PG P   G P   G P  PG G   PPG  GF G P PP   
Sbjct: 668 PGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAP 727

Query: 113 YGGGPAQV-----PLPGGFPGGQMPSQYPGGQPTY 142
             G P ++     P P GFPG       P G+P +
Sbjct: 728 --GTPGRIGLEGPPGPPGFPG-------PKGEPGF 753



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 50/142 (35%), Positives = 56/142 (39%), Gaps = 14/142 (9%)

Query: 10  GYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPAP 69
           G P  PG P    +   P     P   G P + G       S G PG  G   PG  P P
Sbjct: 663 GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPG-------SKGEPGIPGIGLPGP-PGP 714

Query: 70  GGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPGGFPGG 129
            G+PG P P GAP  PG    +G   PPG  GF G    P  +  G P    LP GF G 
Sbjct: 715 KGFPGIPGPPGAPGTPGRIGLEG---PPGPPGFPGPKGEPGFALPGPPGPPGLP-GFKGA 770

Query: 130 QMPSQYPG--GQPTYPSQINTD 149
             P    G  G P  P +   D
Sbjct: 771 LGPKGDRGFPGPPGPPGRTGLD 792



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 54/163 (33%), Positives = 58/163 (35%), Gaps = 27/163 (16%)

Query: 4    PGYP----PTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGG 59
            PG P    P GY   PG P     S  P     P P G P + G    Q    G PG  G
Sbjct: 972  PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG----QPGLIGPPGLKG 1027

Query: 60   YPAPGGYPAPGGYPGAPQPGGAPSYPGVP--PGQ---------------GFGVPPGGAGF 102
                 G+P P G  G P P G P  PG P  PGQ               G   P G  G 
Sbjct: 1028 TIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGL 1087

Query: 103  SGYPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPG--GQPTYP 143
             GYP  P      G   +P   G PG +     PG  G P  P
Sbjct: 1088 PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPP 1130



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 52/141 (36%), Positives = 58/141 (41%), Gaps = 15/141 (10%)

Query: 4    PGYP-PTGYPPFPGYPPAGQESSFPPSGQYPY---PSGFP-PMGGGAYPQVPSSGYPGAG 58
            PG P P G P F G+P   Q    PP    P    P G P P G    P    +G+ G  
Sbjct: 1216 PGLPGPKGEPGFHGFPGV-QGPPGPPGSPGPALEGPKGNPGPQGPPGRPG--PTGFQGLP 1272

Query: 59   GYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPA 118
            G   P G P  GG  G     G P  PG+P  +G   PPG  G  G P        G   
Sbjct: 1273 GPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRP-----GLNGMKG 1327

Query: 119  QVPLPG--GFPGGQMPSQYPG 137
               LPG  GFPG + PS  PG
Sbjct: 1328 DPGLPGVPGFPGMKGPSGVPG 1348



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 49/134 (36%), Positives = 56/134 (41%), Gaps = 11/134 (8%)

Query: 4    PGYPPTGYPPFPGYP-PAGQESSFPPSGQY-----PYPSGFPPMGGGAYPQVPSSGYPGA 57
            PG P  G P FPG   P+G   S  P G+      P P G P   G +      +G PG 
Sbjct: 1329 PGLP--GVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGI 1386

Query: 58   GGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYP-QPPSQSYGG- 115
             G P   G P P G  G P P G P  PG     GF    G  G  G P QP ++   G 
Sbjct: 1387 PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGP 1446

Query: 116  -GPAQVPLPGGFPG 128
             GP  +  P G PG
Sbjct: 1447 PGPDGLQGPPGPPG 1460



 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 49/141 (34%), Positives = 53/141 (37%), Gaps = 13/141 (9%)

Query: 10   GYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPAP 69
            G P  PG  P G++ S    G    P    P   G+  +    G PG  G   P GY   
Sbjct: 929  GQPGLPG--PTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGL 986

Query: 70   GGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYP---QPPSQSYGGGPAQVPLPGGF 126
             G PG P   G P  PG PPG     P G  G  G P    PP      G    P P G 
Sbjct: 987  PGDPGQPGLSGQPGLPG-PPG-----PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGV 1040

Query: 127  PGGQMPSQYPG--GQPTYPSQ 145
             G   PS  PG  G P  P Q
Sbjct: 1041 EGPPGPSGVPGQPGSPGLPGQ 1061



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 47/130 (36%), Positives = 54/130 (41%), Gaps = 6/130 (4%)

Query: 4   PGYP-PTGYPPFPGYPPA-GQESSFPPSGQYPYPSGFP-PMGGGAYPQVPSSGYPGAGGY 60
           PG P P G+P  PG P A G        G  P P GFP P G   +      G PG  G+
Sbjct: 709 PGPPGPKGFPGIPGPPGAPGTPGRIGLEGP-PGPPGFPGPKGEPGFALPGPPGPPGLPGF 767

Query: 61  PAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGG--GPA 118
               G     G+PG P P G     G+P  +G   P G  G  G P  P     G  GP 
Sbjct: 768 KGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPP 827

Query: 119 QVPLPGGFPG 128
            +P P G PG
Sbjct: 828 GIPGPIGQPG 837



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 51/151 (33%), Positives = 57/151 (37%), Gaps = 34/151 (22%)

Query: 3   YPGYP-PTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGG-------------GAYPQ 48
           +PG P P G     G P  G +    P+GQ P P G P + G             G   Q
Sbjct: 779 FPGPPGPPGRTGLDGLP--GPKGDVGPNGQ-PGPMGPPGLPGIGVQGPPGPPGIPGPIGQ 835

Query: 49  VPSSGYPGAGGYPAPGGYPAPG--------GYPGAPQP---GGAPSYPGVPPGQGFGVPP 97
               G PG  G P P G   PG        G PGAP P    G+P  PG     GF    
Sbjct: 836 PGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTK 895

Query: 98  GGAGFSGYPQPPSQSYGGGPAQVPLPGGFPG 128
           G  G  G P PP      GP  +P   G PG
Sbjct: 896 GEMGMMGPPGPP------GPLGIPGRSGVPG 920



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 58/198 (29%), Positives = 67/198 (33%), Gaps = 43/198 (21%)

Query: 4   PGYPPTGYPPFP-GYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPA 62
           PG+P    PP P G P    E         P P G P      YP     G PG  G P 
Sbjct: 137 PGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNP-----GYP-----GPPGIQGLPG 186

Query: 63  PGGYPAPGGYPGAPQPGGAPSYPGVPPGQG-----FGVPPGGAGFSGYPQPPS------- 110
           P G P P G PG P   G P  PG+P  +G     F  P G  G  G   PP        
Sbjct: 187 PTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISE 246

Query: 111 -------------QSYGG-----GPAQVPLPGGFPGGQMPSQYPGGQPTYPSQINTDSFS 152
                        Q   G     GP  +  P G PGG+   +   G+P    +   D  +
Sbjct: 247 QKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGEN 306

Query: 153 SYPVFS--PVSLDYSSEP 168
             P     P    Y  EP
Sbjct: 307 GQPGIPGLPGDPGYPGEP 324



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 56/188 (29%), Positives = 64/188 (34%), Gaps = 56/188 (29%)

Query: 5   GYPPTGYPP-FPGYPPAGQESSFPPSGQYPYPSGFP----PMGGGAYPQVPSSGYPGAGG 59
           G+P    PP  PG  P G     PP      P GFP      G    P +   G PG  G
Sbjct: 374 GFPGIQGPPGLPG--PPGAAVMGPPG-----PPGFPGERGQKGDEGPPGISIPGPPGLDG 426

Query: 60  YPAPGGYPAPGG-------------YPGAPQPGGAPSYPGV------------------- 87
            P   G P P G              PG P P G+P   G+                   
Sbjct: 427 QPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIG 486

Query: 88  -----PPGQ----GFGVPPGGAGFSGYPQPPSQSYGGGPAQVP-LPG--GFPGGQMPSQY 135
                PPGQ    G   PPG  GF G      Q+   GP  +P +PG  G PG       
Sbjct: 487 TGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGE 546

Query: 136 PGGQPTYP 143
           PG   T+P
Sbjct: 547 PGDILTFP 554



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 63/217 (29%), Positives = 70/217 (32%), Gaps = 63/217 (29%)

Query: 1   MSYPGYPPT-GYPPFPGYP----PAGQESSFPPSGQY-----PYPSGFP----------- 39
           +S PG P   G P  PG P    PAG     PPS +      P P G P           
Sbjct: 416 ISIPGPPGLDGQPGAPGLPGPPGPAGPH--IPPSDEICEPGPPGPPGSPGDKGLQGEQGV 473

Query: 40  ------------------PMGGGAYPQVP----SSGYPGAGGYPAPGGYPAPGGYPGAPQ 77
                             P G    P +P    S G+PG  G     G   P G PG P 
Sbjct: 474 KGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPG 533

Query: 78  PGGAPSYPGV--PPGQGFGVP-----------PGGAGFSGYPQPPSQSYGGGPAQVPLPG 124
             GAP +PG    PG     P           PG  G  G P  P Q    G   +P P 
Sbjct: 534 APGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQD---GLPGLPGPK 590

Query: 125 GFPGG--QMPSQYPGGQPTYPSQINTDSFSSYPVFSP 159
           G PGG      + P G P  P           P F P
Sbjct: 591 GEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGP 627



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 46/135 (34%), Positives = 52/135 (38%), Gaps = 11/135 (8%)

Query: 4   PGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGF---PPMGGGAYPQVPSSGYPGAGGY 60
           PG P  G P +PG P    E         P P G     P  G    +  + G PG  G 
Sbjct: 312 PGLP--GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369

Query: 61  PAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQV 120
               G+P   G PG P P GA +  G P   GF   PG  G  G   PP  S  G P   
Sbjct: 370 KGERGFPGIQGPPGLPGPPGA-AVMGPPGPPGF---PGERGQKGDEGPPGISIPGPPGLD 425

Query: 121 PLPG--GFPGGQMPS 133
             PG  G PG   P+
Sbjct: 426 GQPGAPGLPGPPGPA 440



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 54/170 (31%), Positives = 63/170 (37%), Gaps = 33/170 (19%)

Query: 4   PGYP-PTGYPPFPGYP-------PAGQESSFPPS--GQYPYPSGFPPMGGGAYPQVP--- 50
           PG P P G P   G P       P G +   PP   G    P    P+G    P +P   
Sbjct: 827 PGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKA 886

Query: 51  -SSGYPGAGG---YPAPGGYPAPGGYPG-APQPG--------GAPSYPGVPPGQGFGVPP 97
            +SG+PG  G      P G P P G PG +  PG        G P  PG    +G     
Sbjct: 887 GASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKG---SK 943

Query: 98  GGAGFSGYPQPPSQSYGGGPAQVPLPG--GFPGGQMPSQYPG--GQPTYP 143
           G  G  G P P   +  G   +   PG  G PG   P  Y G  G P  P
Sbjct: 944 GEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQP 993



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 39/111 (35%), Positives = 44/111 (39%), Gaps = 23/111 (20%)

Query: 53  GYPGAGGYPAPGGYPAPGGYPGAPQPGGAP---------SYPGVPPGQGFGVPPGGAGFS 103
           G  G  G+P   G+P   G PG P P G P           PG P  +G   PPG  GF 
Sbjct: 45  GEKGERGFPGLEGHP---GLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101

Query: 104 GYPQPPSQ-SYGGGPAQVPLPG--------GFPG--GQMPSQYPGGQPTYP 143
           G P  P    + G P    +PG        GFPG  G    Q P G P  P
Sbjct: 102 GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIP 152



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 44/133 (33%), Positives = 50/133 (37%), Gaps = 28/133 (21%)

Query: 37  GFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVP-----PGQ 91
           G P   GG   +    G PG  G P   G     G PG P   G P YPG P      GQ
Sbjct: 276 GPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP---GDPGYPGEPGRDGEKGQ 332

Query: 92  -GFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPG--------GFPGGQMPSQYPG----- 137
            G   PPG  G    P+P +    G    + LPG        GFPG Q P   PG     
Sbjct: 333 KGDTGPPGPPGLV-IPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAA 391

Query: 138 -----GQPTYPSQ 145
                G P +P +
Sbjct: 392 VMGPPGPPGFPGE 404



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 51/182 (28%), Positives = 60/182 (32%), Gaps = 44/182 (24%)

Query: 8   PTGYPPFPGYPPAGQESSFP-PSGQYPYPSGFPPMGGGAYPQVPSS-GYPGAGGYP---- 61
           P G P  PG P       FP   G+        P G    P  P + G+PG+ G P    
Sbjct: 492 PPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDIL 551

Query: 62  -------------APGGYPAPG--GYPGAPQPGGAPSYPGVPPG---QGFGVPPGGAGFS 103
                        +PG    PG  G PG     G P   G P G   +G   PPG  G  
Sbjct: 552 TFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLP 611

Query: 104 GYP------QPPS------------QSYGGGPAQ--VPLPGGFPGGQMPSQYPGGQPTYP 143
           G P       PP             Q   G P Q  +P P G PG  +      G P  P
Sbjct: 612 GLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNP 671

Query: 144 SQ 145
            +
Sbjct: 672 GR 673



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 58/206 (28%), Positives = 64/206 (31%), Gaps = 29/206 (14%)

Query: 4    PGYP-------PTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGG--GAYPQVPSSGY 54
            PG P       P G    PG P        P     P   GFP M G  G        G 
Sbjct: 1299 PGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVP---GFPGMKGPSGVPGSAGPEGE 1355

Query: 55   PGAGGYPAPGGYPAPGGY----------PGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSG 104
            PG  G P P G P P G           PG P   G    PG    QG   P G  G  G
Sbjct: 1356 PGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPG 1415

Query: 105  YPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPG--GQPTYPSQINTDSFSSYPVFSPVSL 162
                P     GG    P   G PG +     PG  G    P    T S     V     +
Sbjct: 1416 RNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSS-----VAHGFLI 1470

Query: 163  DYSSEPATVTQVTQGTIRPAANFDAI 188
               S+     Q  QGT++    F  +
Sbjct: 1471 TRHSQTTDAPQCPQGTLQVYEGFSLL 1496



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 39/114 (34%), Positives = 42/114 (36%), Gaps = 14/114 (12%)

Query: 15  PGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPAPGGYPG 74
           PG P    E  FP       P G P   G A       G PG  G+P   G     G PG
Sbjct: 364 PGLPGEKGERGFPG---IQGPPGLPGPPGAAV-----MGPPGPPGFPGERGQKGDEGPPG 415

Query: 75  APQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPGGFPG 128
              P G P   G P   G   PPG AG   +  P  +    GP   P P G PG
Sbjct: 416 ISIP-GPPGLDGQPGAPGLPGPPGPAG--PHIPPSDEICEPGP---PGPPGSPG 463



 Score = 37.4 bits (85), Expect = 0.031
 Identities = 24/64 (37%), Positives = 26/64 (40%), Gaps = 3/64 (4%)

Query: 65  GYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPG 124
           G     G  G P   G P  PG P  +G   P G  G  G P PP      GP  +P   
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLP--- 98

Query: 125 GFPG 128
           GFPG
Sbjct: 99  GFPG 102


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
           sapiens]
          Length = 1685

 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 56/155 (36%), Positives = 61/155 (39%), Gaps = 18/155 (11%)

Query: 8   PTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGG--GAYPQVPSSGYPGAGGYPAPGG 65
           P G P FPG P        P     P P G P   G  G      S G+PG  G P P G
Sbjct: 94  PPGLPGFPGTPGL---PGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPG 150

Query: 66  YPAPGGYPGA------PQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQ 119
            P   G PG+      P P G P YPG P  QG   P G  G  G P PP      GP  
Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210

Query: 120 VPLPGG-------FPGGQMPSQYPGGQPTYPSQIN 147
           +P P G        P G+   Q   G P  P QI+
Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQIS 245



 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 52/146 (35%), Positives = 60/146 (41%), Gaps = 27/146 (18%)

Query: 5   GYPPT-GYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSS----GYPGAGG 59
           G+P   G+P  PG+P  G E    P GQ          G    P  P      G PG  G
Sbjct: 51  GFPGLEGHPGLPGFP--GPEGPPGPRGQ---------KGDDGIPGPPGPKGIRGPPGLPG 99

Query: 60  YPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQ 119
           +P   G P   G+ GAP P G P   G    +GF   PG  GF G   PP      GP  
Sbjct: 100 FPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGF---PGSPGFPGLQGPP------GPPG 150

Query: 120 VPLPGGFPGGQMPSQYPG--GQPTYP 143
           +P   G PG  + S  PG  G P YP
Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYP 176



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 56/171 (32%), Positives = 61/171 (35%), Gaps = 37/171 (21%)

Query: 4    PGYPPT-------GYPPFPGYP-PAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPS---- 51
            PG P T       G P FPG P P G +    P G    P    P+GGG +P  P     
Sbjct: 1106 PGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGE 1165

Query: 52   SGYPGAGGYPAPGGY-----------PAP------------GGYPGAPQPGGAPSYPGVP 88
             G PG  G P P G            P P            GG PG P   G P   G P
Sbjct: 1166 KGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEP 1225

Query: 89   PGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPG--GFPGGQMPSQYPG 137
               GF    G  G  G P P  +   G P     PG  G PG + P   PG
Sbjct: 1226 GFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPG 1276



 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 58/166 (34%), Positives = 65/166 (39%), Gaps = 26/166 (15%)

Query: 4    PGYP-PTGYPPFPGYP----PAGQESSFPPSGQYPYPSGF--PPMGGGAYPQVPSSGYPG 56
            PG P P G P  PG P    P G + +    G +P P G   PP   G   Q  S G PG
Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMG-FPGPQGVEGPPGPSGVPGQPGSPGLPG 1060

Query: 57   AGG--------------YPAPGGYPAPGGYPGAPQPGGA---PSYPGVPPGQGFGVPPGG 99
              G               P P G P   GYPG P   G+   P  PG+P   G    PG 
Sbjct: 1061 QKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGL 1120

Query: 100  AGFSGYPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPGGQPTYPSQ 145
             GF G P PP      GP   P   G PG      +P GQP  P +
Sbjct: 1121 PGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHP-GQPGPPGE 1165



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 52/143 (36%), Positives = 58/143 (40%), Gaps = 26/143 (18%)

Query: 4    PGYP-PTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPA 62
            PG P P G P  PGYP                P     +G    P +P  G PGA G P 
Sbjct: 1076 PGLPGPKGEPGLPGYPGN--------------PGIKGSVGDPGLPGLP--GTPGAKGQPG 1119

Query: 63   PGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPL 122
              G+P   G PG     G P  PG+P   G   P GG G  G P PP +   G P Q  +
Sbjct: 1120 LPGFPGTPGPPGPKGISGPPGNPGLPGEPG---PVGGGGHPGQPGPPGEK--GKPGQDGI 1174

Query: 123  PGGFPGGQM--PSQYPGGQPTYP 143
            PG  P GQ   P Q   G P  P
Sbjct: 1175 PG--PAGQKGEPGQPGFGNPGPP 1195



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 53/155 (34%), Positives = 60/155 (38%), Gaps = 28/155 (18%)

Query: 4   PGYP----PTGYPPFPGYPPAGQE-----SSFPPSGQYPYPSGFPPMGGGAYPQVPSSGY 54
           PG P    P G P F    P G++     +  P     P P G P   G    Q    G 
Sbjct: 611 PGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDP---GQTITQPGKPGL 667

Query: 55  PGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVP--PGQGFGVPPGGAGFSGYPQPPSQS 112
           PG  G     G P   G PG P   G P   G P  PG G   PPG  GF G P PP   
Sbjct: 668 PGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAP 727

Query: 113 YGGGPAQV-----PLPGGFPGGQMPSQYPGGQPTY 142
             G P ++     P P GFPG       P G+P +
Sbjct: 728 --GTPGRIGLEGPPGPPGFPG-------PKGEPGF 753



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 50/142 (35%), Positives = 56/142 (39%), Gaps = 14/142 (9%)

Query: 10  GYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPAP 69
           G P  PG P    +   P     P   G P + G       S G PG  G   PG  P P
Sbjct: 663 GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPG-------SKGEPGIPGIGLPGP-PGP 714

Query: 70  GGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPGGFPGG 129
            G+PG P P GAP  PG    +G   PPG  GF G    P  +  G P    LP GF G 
Sbjct: 715 KGFPGIPGPPGAPGTPGRIGLEG---PPGPPGFPGPKGEPGFALPGPPGPPGLP-GFKGA 770

Query: 130 QMPSQYPG--GQPTYPSQINTD 149
             P    G  G P  P +   D
Sbjct: 771 LGPKGDRGFPGPPGPPGRTGLD 792



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 54/163 (33%), Positives = 58/163 (35%), Gaps = 27/163 (16%)

Query: 4    PGYP----PTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGG 59
            PG P    P GY   PG P     S  P     P P G P + G    Q    G PG  G
Sbjct: 972  PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG----QPGLIGPPGLKG 1027

Query: 60   YPAPGGYPAPGGYPGAPQPGGAPSYPGVP--PGQ---------------GFGVPPGGAGF 102
                 G+P P G  G P P G P  PG P  PGQ               G   P G  G 
Sbjct: 1028 TIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGL 1087

Query: 103  SGYPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPG--GQPTYP 143
             GYP  P      G   +P   G PG +     PG  G P  P
Sbjct: 1088 PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPP 1130



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 49/134 (36%), Positives = 56/134 (41%), Gaps = 11/134 (8%)

Query: 4    PGYPPTGYPPFPGYP-PAGQESSFPPSGQY-----PYPSGFPPMGGGAYPQVPSSGYPGA 57
            PG P  G P FPG   P+G   S  P G+      P P G P   G +      +G PG 
Sbjct: 1323 PGLP--GVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGI 1380

Query: 58   GGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYP-QPPSQSYGG- 115
             G P   G P P G  G P P G P  PG     GF    G  G  G P QP ++   G 
Sbjct: 1381 PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGP 1440

Query: 116  -GPAQVPLPGGFPG 128
             GP  +  P G PG
Sbjct: 1441 PGPDGLQGPPGPPG 1454



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 49/135 (36%), Positives = 54/135 (40%), Gaps = 9/135 (6%)

Query: 4    PGYP-PTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPA 62
            PG P P G P F G+P   Q    PP    P   G  P G    PQ P    PG  G P 
Sbjct: 1216 PGLPGPKGEPGFHGFPGV-QGPPGPPGSPGPALEG--PKGNPG-PQGP----PGRPGLPG 1267

Query: 63   PGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPL 122
            P G P   G  G     G P  PG+P   G     G  G  G P  P  +   G   +P 
Sbjct: 1268 PEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPG 1327

Query: 123  PGGFPGGQMPSQYPG 137
              GFPG + PS  PG
Sbjct: 1328 VPGFPGMKGPSGVPG 1342



 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 49/141 (34%), Positives = 53/141 (37%), Gaps = 13/141 (9%)

Query: 10   GYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPAP 69
            G P  PG  P G++ S    G    P    P   G+  +    G PG  G   P GY   
Sbjct: 929  GQPGLPG--PTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGL 986

Query: 70   GGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYP---QPPSQSYGGGPAQVPLPGGF 126
             G PG P   G P  PG PPG     P G  G  G P    PP      G    P P G 
Sbjct: 987  PGDPGQPGLSGQPGLPG-PPG-----PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGV 1040

Query: 127  PGGQMPSQYPG--GQPTYPSQ 145
             G   PS  PG  G P  P Q
Sbjct: 1041 EGPPGPSGVPGQPGSPGLPGQ 1061



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 47/130 (36%), Positives = 54/130 (41%), Gaps = 6/130 (4%)

Query: 4   PGYP-PTGYPPFPGYPPA-GQESSFPPSGQYPYPSGFP-PMGGGAYPQVPSSGYPGAGGY 60
           PG P P G+P  PG P A G        G  P P GFP P G   +      G PG  G+
Sbjct: 709 PGPPGPKGFPGIPGPPGAPGTPGRIGLEGP-PGPPGFPGPKGEPGFALPGPPGPPGLPGF 767

Query: 61  PAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGG--GPA 118
               G     G+PG P P G     G+P  +G   P G  G  G P  P     G  GP 
Sbjct: 768 KGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPP 827

Query: 119 QVPLPGGFPG 128
            +P P G PG
Sbjct: 828 GIPGPIGQPG 837



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 51/151 (33%), Positives = 57/151 (37%), Gaps = 34/151 (22%)

Query: 3   YPGYP-PTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGG-------------GAYPQ 48
           +PG P P G     G P  G +    P+GQ P P G P + G             G   Q
Sbjct: 779 FPGPPGPPGRTGLDGLP--GPKGDVGPNGQ-PGPMGPPGLPGIGVQGPPGPPGIPGPIGQ 835

Query: 49  VPSSGYPGAGGYPAPGGYPAPG--------GYPGAPQP---GGAPSYPGVPPGQGFGVPP 97
               G PG  G P P G   PG        G PGAP P    G+P  PG     GF    
Sbjct: 836 PGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTK 895

Query: 98  GGAGFSGYPQPPSQSYGGGPAQVPLPGGFPG 128
           G  G  G P PP      GP  +P   G PG
Sbjct: 896 GEMGMMGPPGPP------GPLGIPGRSGVPG 920



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 58/198 (29%), Positives = 67/198 (33%), Gaps = 43/198 (21%)

Query: 4   PGYPPTGYPPFP-GYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPA 62
           PG+P    PP P G P    E         P P G P      YP     G PG  G P 
Sbjct: 137 PGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNP-----GYP-----GPPGIQGLPG 186

Query: 63  PGGYPAPGGYPGAPQPGGAPSYPGVPPGQG-----FGVPPGGAGFSGYPQPPS------- 110
           P G P P G PG P   G P  PG+P  +G     F  P G  G  G   PP        
Sbjct: 187 PTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISE 246

Query: 111 -------------QSYGG-----GPAQVPLPGGFPGGQMPSQYPGGQPTYPSQINTDSFS 152
                        Q   G     GP  +  P G PGG+   +   G+P    +   D  +
Sbjct: 247 QKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGEN 306

Query: 153 SYPVFS--PVSLDYSSEP 168
             P     P    Y  EP
Sbjct: 307 GQPGIPGLPGDPGYPGEP 324



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 56/188 (29%), Positives = 64/188 (34%), Gaps = 56/188 (29%)

Query: 5   GYPPTGYPP-FPGYPPAGQESSFPPSGQYPYPSGFP----PMGGGAYPQVPSSGYPGAGG 59
           G+P    PP  PG  P G     PP      P GFP      G    P +   G PG  G
Sbjct: 374 GFPGIQGPPGLPG--PPGAAVMGPPG-----PPGFPGERGQKGDEGPPGISIPGPPGLDG 426

Query: 60  YPAPGGYPAPGG-------------YPGAPQPGGAPSYPGV------------------- 87
            P   G P P G              PG P P G+P   G+                   
Sbjct: 427 QPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIG 486

Query: 88  -----PPGQ----GFGVPPGGAGFSGYPQPPSQSYGGGPAQVP-LPG--GFPGGQMPSQY 135
                PPGQ    G   PPG  GF G      Q+   GP  +P +PG  G PG       
Sbjct: 487 TGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGE 546

Query: 136 PGGQPTYP 143
           PG   T+P
Sbjct: 547 PGDILTFP 554



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 63/217 (29%), Positives = 70/217 (32%), Gaps = 63/217 (29%)

Query: 1   MSYPGYPPT-GYPPFPGYP----PAGQESSFPPSGQY-----PYPSGFP----------- 39
           +S PG P   G P  PG P    PAG     PPS +      P P G P           
Sbjct: 416 ISIPGPPGLDGQPGAPGLPGPPGPAGPH--IPPSDEICEPGPPGPPGSPGDKGLQGEQGV 473

Query: 40  ------------------PMGGGAYPQVP----SSGYPGAGGYPAPGGYPAPGGYPGAPQ 77
                             P G    P +P    S G+PG  G     G   P G PG P 
Sbjct: 474 KGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPG 533

Query: 78  PGGAPSYPGV--PPGQGFGVP-----------PGGAGFSGYPQPPSQSYGGGPAQVPLPG 124
             GAP +PG    PG     P           PG  G  G P  P Q    G   +P P 
Sbjct: 534 APGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQD---GLPGLPGPK 590

Query: 125 GFPGG--QMPSQYPGGQPTYPSQINTDSFSSYPVFSP 159
           G PGG      + P G P  P           P F P
Sbjct: 591 GEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGP 627



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 46/135 (34%), Positives = 52/135 (38%), Gaps = 11/135 (8%)

Query: 4   PGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGF---PPMGGGAYPQVPSSGYPGAGGY 60
           PG P  G P +PG P    E         P P G     P  G    +  + G PG  G 
Sbjct: 312 PGLP--GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369

Query: 61  PAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQV 120
               G+P   G PG P P GA +  G P   GF   PG  G  G   PP  S  G P   
Sbjct: 370 KGERGFPGIQGPPGLPGPPGA-AVMGPPGPPGF---PGERGQKGDEGPPGISIPGPPGLD 425

Query: 121 PLPG--GFPGGQMPS 133
             PG  G PG   P+
Sbjct: 426 GQPGAPGLPGPPGPA 440



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 54/170 (31%), Positives = 63/170 (37%), Gaps = 33/170 (19%)

Query: 4   PGYP-PTGYPPFPGYP-------PAGQESSFPPS--GQYPYPSGFPPMGGGAYPQVP--- 50
           PG P P G P   G P       P G +   PP   G    P    P+G    P +P   
Sbjct: 827 PGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKA 886

Query: 51  -SSGYPGAGG---YPAPGGYPAPGGYPG-APQPG--------GAPSYPGVPPGQGFGVPP 97
            +SG+PG  G      P G P P G PG +  PG        G P  PG    +G     
Sbjct: 887 GASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKG---SK 943

Query: 98  GGAGFSGYPQPPSQSYGGGPAQVPLPG--GFPGGQMPSQYPG--GQPTYP 143
           G  G  G P P   +  G   +   PG  G PG   P  Y G  G P  P
Sbjct: 944 GEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQP 993



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 39/111 (35%), Positives = 44/111 (39%), Gaps = 23/111 (20%)

Query: 53  GYPGAGGYPAPGGYPAPGGYPGAPQPGGAP---------SYPGVPPGQGFGVPPGGAGFS 103
           G  G  G+P   G+P   G PG P P G P           PG P  +G   PPG  GF 
Sbjct: 45  GEKGERGFPGLEGHP---GLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101

Query: 104 GYPQPPSQ-SYGGGPAQVPLPG--------GFPG--GQMPSQYPGGQPTYP 143
           G P  P    + G P    +PG        GFPG  G    Q P G P  P
Sbjct: 102 GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIP 152



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 44/133 (33%), Positives = 50/133 (37%), Gaps = 28/133 (21%)

Query: 37  GFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVP-----PGQ 91
           G P   GG   +    G PG  G P   G     G PG P   G P YPG P      GQ
Sbjct: 276 GPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP---GDPGYPGEPGRDGEKGQ 332

Query: 92  -GFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPG--------GFPGGQMPSQYPG----- 137
            G   PPG  G    P+P +    G    + LPG        GFPG Q P   PG     
Sbjct: 333 KGDTGPPGPPGLV-IPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAA 391

Query: 138 -----GQPTYPSQ 145
                G P +P +
Sbjct: 392 VMGPPGPPGFPGE 404



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 51/182 (28%), Positives = 60/182 (32%), Gaps = 44/182 (24%)

Query: 8   PTGYPPFPGYPPAGQESSFP-PSGQYPYPSGFPPMGGGAYPQVPSS-GYPGAGGYP---- 61
           P G P  PG P       FP   G+        P G    P  P + G+PG+ G P    
Sbjct: 492 PPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDIL 551

Query: 62  -------------APGGYPAPG--GYPGAPQPGGAPSYPGVPPG---QGFGVPPGGAGFS 103
                        +PG    PG  G PG     G P   G P G   +G   PPG  G  
Sbjct: 552 TFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLP 611

Query: 104 GYP------QPPS------------QSYGGGPAQ--VPLPGGFPGGQMPSQYPGGQPTYP 143
           G P       PP             Q   G P Q  +P P G PG  +      G P  P
Sbjct: 612 GLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNP 671

Query: 144 SQ 145
            +
Sbjct: 672 GR 673



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 58/206 (28%), Positives = 64/206 (31%), Gaps = 29/206 (14%)

Query: 4    PGYP-------PTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGG--GAYPQVPSSGY 54
            PG P       P G    PG P        P     P   GFP M G  G        G 
Sbjct: 1293 PGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVP---GFPGMKGPSGVPGSAGPEGE 1349

Query: 55   PGAGGYPAPGGYPAPGGY----------PGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSG 104
            PG  G P P G P P G           PG P   G    PG    QG   P G  G  G
Sbjct: 1350 PGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPG 1409

Query: 105  YPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPG--GQPTYPSQINTDSFSSYPVFSPVSL 162
                P     GG    P   G PG +     PG  G    P    T S     V     +
Sbjct: 1410 RNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSS-----VAHGFLI 1464

Query: 163  DYSSEPATVTQVTQGTIRPAANFDAI 188
               S+     Q  QGT++    F  +
Sbjct: 1465 TRHSQTTDAPQCPQGTLQVYEGFSLL 1490



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 39/114 (34%), Positives = 42/114 (36%), Gaps = 14/114 (12%)

Query: 15  PGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPAPGGYPG 74
           PG P    E  FP       P G P   G A       G PG  G+P   G     G PG
Sbjct: 364 PGLPGEKGERGFPG---IQGPPGLPGPPGAAV-----MGPPGPPGFPGERGQKGDEGPPG 415

Query: 75  APQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPGGFPG 128
              P G P   G P   G   PPG AG   +  P  +    GP   P P G PG
Sbjct: 416 ISIP-GPPGLDGQPGAPGLPGPPGPAG--PHIPPSDEICEPGP---PGPPGSPG 463



 Score = 37.4 bits (85), Expect = 0.031
 Identities = 24/64 (37%), Positives = 26/64 (40%), Gaps = 3/64 (4%)

Query: 65  GYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPG 124
           G     G  G P   G P  PG P  +G   P G  G  G P PP      GP  +P   
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLP--- 98

Query: 125 GFPG 128
           GFPG
Sbjct: 99  GFPG 102


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
           sapiens]
          Length = 1688

 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 56/155 (36%), Positives = 61/155 (39%), Gaps = 18/155 (11%)

Query: 8   PTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGG--GAYPQVPSSGYPGAGGYPAPGG 65
           P G P FPG P        P     P P G P   G  G      S G+PG  G P P G
Sbjct: 94  PPGLPGFPGTPGL---PGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPG 150

Query: 66  YPAPGGYPGA------PQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQ 119
            P   G PG+      P P G P YPG P  QG   P G  G  G P PP      GP  
Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210

Query: 120 VPLPGG-------FPGGQMPSQYPGGQPTYPSQIN 147
           +P P G        P G+   Q   G P  P QI+
Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQIS 245



 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 52/146 (35%), Positives = 60/146 (41%), Gaps = 27/146 (18%)

Query: 5   GYPPT-GYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSS----GYPGAGG 59
           G+P   G+P  PG+P  G E    P GQ          G    P  P      G PG  G
Sbjct: 51  GFPGLEGHPGLPGFP--GPEGPPGPRGQ---------KGDDGIPGPPGPKGIRGPPGLPG 99

Query: 60  YPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQ 119
           +P   G P   G+ GAP P G P   G    +GF   PG  GF G   PP      GP  
Sbjct: 100 FPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGF---PGSPGFPGLQGPP------GPPG 150

Query: 120 VPLPGGFPGGQMPSQYPG--GQPTYP 143
           +P   G PG  + S  PG  G P YP
Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYP 176



 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 60/171 (35%), Positives = 65/171 (38%), Gaps = 45/171 (26%)

Query: 4    PGYPPT-------GYPPFPGYP-PAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPS---- 51
            PG P T       G P FPG P P G +    P G    P    P+GGG +P  P     
Sbjct: 1106 PGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGE 1165

Query: 52   SGYPGAGGYPAPGGY-----------PAP------------GGYPGAPQPGGAPSYPGVP 88
             G PG  G P P G            P P            GG PG P   G P  PG P
Sbjct: 1166 KGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIP---GNPGLPG-P 1221

Query: 89   PGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPGGQ 139
             G+     PG  GF G   PP      GPA +  P G PG Q P   PG Q
Sbjct: 1222 KGE-----PGFHGFPGVQGPPGPPGSPGPA-LEGPKGNPGPQGPPGRPGFQ 1266



 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 58/166 (34%), Positives = 65/166 (39%), Gaps = 26/166 (15%)

Query: 4    PGYP-PTGYPPFPGYP----PAGQESSFPPSGQYPYPSGF--PPMGGGAYPQVPSSGYPG 56
            PG P P G P  PG P    P G + +    G +P P G   PP   G   Q  S G PG
Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMG-FPGPQGVEGPPGPSGVPGQPGSPGLPG 1060

Query: 57   AGG--------------YPAPGGYPAPGGYPGAPQPGGA---PSYPGVPPGQGFGVPPGG 99
              G               P P G P   GYPG P   G+   P  PG+P   G    PG 
Sbjct: 1061 QKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGL 1120

Query: 100  AGFSGYPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPGGQPTYPSQ 145
             GF G P PP      GP   P   G PG      +P GQP  P +
Sbjct: 1121 PGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHP-GQPGPPGE 1165



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 52/143 (36%), Positives = 58/143 (40%), Gaps = 26/143 (18%)

Query: 4    PGYP-PTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPA 62
            PG P P G P  PGYP                P     +G    P +P  G PGA G P 
Sbjct: 1076 PGLPGPKGEPGLPGYPGN--------------PGIKGSVGDPGLPGLP--GTPGAKGQPG 1119

Query: 63   PGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPL 122
              G+P   G PG     G P  PG+P   G   P GG G  G P PP +   G P Q  +
Sbjct: 1120 LPGFPGTPGPPGPKGISGPPGNPGLPGEPG---PVGGGGHPGQPGPPGEK--GKPGQDGI 1174

Query: 123  PGGFPGGQM--PSQYPGGQPTYP 143
            PG  P GQ   P Q   G P  P
Sbjct: 1175 PG--PAGQKGEPGQPGFGNPGPP 1195



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 53/155 (34%), Positives = 60/155 (38%), Gaps = 28/155 (18%)

Query: 4   PGYP----PTGYPPFPGYPPAGQE-----SSFPPSGQYPYPSGFPPMGGGAYPQVPSSGY 54
           PG P    P G P F    P G++     +  P     P P G P   G    Q    G 
Sbjct: 611 PGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDP---GQTITQPGKPGL 667

Query: 55  PGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVP--PGQGFGVPPGGAGFSGYPQPPSQS 112
           PG  G     G P   G PG P   G P   G P  PG G   PPG  GF G P PP   
Sbjct: 668 PGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAP 727

Query: 113 YGGGPAQV-----PLPGGFPGGQMPSQYPGGQPTY 142
             G P ++     P P GFPG       P G+P +
Sbjct: 728 --GTPGRIGLEGPPGPPGFPG-------PKGEPGF 753



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 50/142 (35%), Positives = 56/142 (39%), Gaps = 14/142 (9%)

Query: 10  GYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPAP 69
           G P  PG P    +   P     P   G P + G       S G PG  G   PG  P P
Sbjct: 663 GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPG-------SKGEPGIPGIGLPGP-PGP 714

Query: 70  GGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPGGFPGG 129
            G+PG P P GAP  PG    +G   PPG  GF G    P  +  G P    LP GF G 
Sbjct: 715 KGFPGIPGPPGAPGTPGRIGLEG---PPGPPGFPGPKGEPGFALPGPPGPPGLP-GFKGA 770

Query: 130 QMPSQYPG--GQPTYPSQINTD 149
             P    G  G P  P +   D
Sbjct: 771 LGPKGDRGFPGPPGPPGRTGLD 792



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 50/135 (37%), Positives = 55/135 (40%), Gaps = 6/135 (4%)

Query: 4    PGYP-PTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPA 62
            PG P P G P F G+P   Q    PP    P   G  P G    PQ P  G PG  G P 
Sbjct: 1216 PGLPGPKGEPGFHGFPGV-QGPPGPPGSPGPALEG--PKGNPG-PQGPP-GRPGFQGLPG 1270

Query: 63   PGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPL 122
            P G P   G  G     G P  PG+P   G     G  G  G P  P  +   G   +P 
Sbjct: 1271 PEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPG 1330

Query: 123  PGGFPGGQMPSQYPG 137
              GFPG + PS  PG
Sbjct: 1331 VPGFPGMKGPSGVPG 1345



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 54/163 (33%), Positives = 58/163 (35%), Gaps = 27/163 (16%)

Query: 4    PGYP----PTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGG 59
            PG P    P GY   PG P     S  P     P P G P + G    Q    G PG  G
Sbjct: 972  PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG----QPGLIGPPGLKG 1027

Query: 60   YPAPGGYPAPGGYPGAPQPGGAPSYPGVP--PGQ---------------GFGVPPGGAGF 102
                 G+P P G  G P P G P  PG P  PGQ               G   P G  G 
Sbjct: 1028 TIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGL 1087

Query: 103  SGYPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPG--GQPTYP 143
             GYP  P      G   +P   G PG +     PG  G P  P
Sbjct: 1088 PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPP 1130



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 49/134 (36%), Positives = 56/134 (41%), Gaps = 11/134 (8%)

Query: 4    PGYPPTGYPPFPGYP-PAGQESSFPPSGQY-----PYPSGFPPMGGGAYPQVPSSGYPGA 57
            PG P  G P FPG   P+G   S  P G+      P P G P   G +      +G PG 
Sbjct: 1326 PGLP--GVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGI 1383

Query: 58   GGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYP-QPPSQSYGG- 115
             G P   G P P G  G P P G P  PG     GF    G  G  G P QP ++   G 
Sbjct: 1384 PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGP 1443

Query: 116  -GPAQVPLPGGFPG 128
             GP  +  P G PG
Sbjct: 1444 PGPDGLQGPPGPPG 1457



 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 49/141 (34%), Positives = 53/141 (37%), Gaps = 13/141 (9%)

Query: 10   GYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPAP 69
            G P  PG  P G++ S    G    P    P   G+  +    G PG  G   P GY   
Sbjct: 929  GQPGLPG--PTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGL 986

Query: 70   GGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYP---QPPSQSYGGGPAQVPLPGGF 126
             G PG P   G P  PG PPG     P G  G  G P    PP      G    P P G 
Sbjct: 987  PGDPGQPGLSGQPGLPG-PPG-----PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGV 1040

Query: 127  PGGQMPSQYPG--GQPTYPSQ 145
             G   PS  PG  G P  P Q
Sbjct: 1041 EGPPGPSGVPGQPGSPGLPGQ 1061



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 47/130 (36%), Positives = 54/130 (41%), Gaps = 6/130 (4%)

Query: 4   PGYP-PTGYPPFPGYPPA-GQESSFPPSGQYPYPSGFP-PMGGGAYPQVPSSGYPGAGGY 60
           PG P P G+P  PG P A G        G  P P GFP P G   +      G PG  G+
Sbjct: 709 PGPPGPKGFPGIPGPPGAPGTPGRIGLEGP-PGPPGFPGPKGEPGFALPGPPGPPGLPGF 767

Query: 61  PAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGG--GPA 118
               G     G+PG P P G     G+P  +G   P G  G  G P  P     G  GP 
Sbjct: 768 KGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPP 827

Query: 119 QVPLPGGFPG 128
            +P P G PG
Sbjct: 828 GIPGPIGQPG 837



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 51/151 (33%), Positives = 57/151 (37%), Gaps = 34/151 (22%)

Query: 3   YPGYP-PTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGG-------------GAYPQ 48
           +PG P P G     G P  G +    P+GQ P P G P + G             G   Q
Sbjct: 779 FPGPPGPPGRTGLDGLP--GPKGDVGPNGQ-PGPMGPPGLPGIGVQGPPGPPGIPGPIGQ 835

Query: 49  VPSSGYPGAGGYPAPGGYPAPG--------GYPGAPQP---GGAPSYPGVPPGQGFGVPP 97
               G PG  G P P G   PG        G PGAP P    G+P  PG     GF    
Sbjct: 836 PGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTK 895

Query: 98  GGAGFSGYPQPPSQSYGGGPAQVPLPGGFPG 128
           G  G  G P PP      GP  +P   G PG
Sbjct: 896 GEMGMMGPPGPP------GPLGIPGRSGVPG 920



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 58/198 (29%), Positives = 67/198 (33%), Gaps = 43/198 (21%)

Query: 4   PGYPPTGYPPFP-GYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPA 62
           PG+P    PP P G P    E         P P G P      YP     G PG  G P 
Sbjct: 137 PGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNP-----GYP-----GPPGIQGLPG 186

Query: 63  PGGYPAPGGYPGAPQPGGAPSYPGVPPGQG-----FGVPPGGAGFSGYPQPPS------- 110
           P G P P G PG P   G P  PG+P  +G     F  P G  G  G   PP        
Sbjct: 187 PTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISE 246

Query: 111 -------------QSYGG-----GPAQVPLPGGFPGGQMPSQYPGGQPTYPSQINTDSFS 152
                        Q   G     GP  +  P G PGG+   +   G+P    +   D  +
Sbjct: 247 QKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGEN 306

Query: 153 SYPVFS--PVSLDYSSEP 168
             P     P    Y  EP
Sbjct: 307 GQPGIPGLPGDPGYPGEP 324



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 56/188 (29%), Positives = 64/188 (34%), Gaps = 56/188 (29%)

Query: 5   GYPPTGYPP-FPGYPPAGQESSFPPSGQYPYPSGFP----PMGGGAYPQVPSSGYPGAGG 59
           G+P    PP  PG  P G     PP      P GFP      G    P +   G PG  G
Sbjct: 374 GFPGIQGPPGLPG--PPGAAVMGPPG-----PPGFPGERGQKGDEGPPGISIPGPPGLDG 426

Query: 60  YPAPGGYPAPGG-------------YPGAPQPGGAPSYPGV------------------- 87
            P   G P P G              PG P P G+P   G+                   
Sbjct: 427 QPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIG 486

Query: 88  -----PPGQ----GFGVPPGGAGFSGYPQPPSQSYGGGPAQVP-LPG--GFPGGQMPSQY 135
                PPGQ    G   PPG  GF G      Q+   GP  +P +PG  G PG       
Sbjct: 487 TGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGE 546

Query: 136 PGGQPTYP 143
           PG   T+P
Sbjct: 547 PGDILTFP 554



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 63/217 (29%), Positives = 70/217 (32%), Gaps = 63/217 (29%)

Query: 1   MSYPGYPPT-GYPPFPGYP----PAGQESSFPPSGQY-----PYPSGFP----------- 39
           +S PG P   G P  PG P    PAG     PPS +      P P G P           
Sbjct: 416 ISIPGPPGLDGQPGAPGLPGPPGPAGPH--IPPSDEICEPGPPGPPGSPGDKGLQGEQGV 473

Query: 40  ------------------PMGGGAYPQVP----SSGYPGAGGYPAPGGYPAPGGYPGAPQ 77
                             P G    P +P    S G+PG  G     G   P G PG P 
Sbjct: 474 KGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPG 533

Query: 78  PGGAPSYPGV--PPGQGFGVP-----------PGGAGFSGYPQPPSQSYGGGPAQVPLPG 124
             GAP +PG    PG     P           PG  G  G P  P Q    G   +P P 
Sbjct: 534 APGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQD---GLPGLPGPK 590

Query: 125 GFPGG--QMPSQYPGGQPTYPSQINTDSFSSYPVFSP 159
           G PGG      + P G P  P           P F P
Sbjct: 591 GEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGP 627



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 46/135 (34%), Positives = 52/135 (38%), Gaps = 11/135 (8%)

Query: 4   PGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGF---PPMGGGAYPQVPSSGYPGAGGY 60
           PG P  G P +PG P    E         P P G     P  G    +  + G PG  G 
Sbjct: 312 PGLP--GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369

Query: 61  PAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQV 120
               G+P   G PG P P GA +  G P   GF   PG  G  G   PP  S  G P   
Sbjct: 370 KGERGFPGIQGPPGLPGPPGA-AVMGPPGPPGF---PGERGQKGDEGPPGISIPGPPGLD 425

Query: 121 PLPG--GFPGGQMPS 133
             PG  G PG   P+
Sbjct: 426 GQPGAPGLPGPPGPA 440



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 54/170 (31%), Positives = 63/170 (37%), Gaps = 33/170 (19%)

Query: 4   PGYP-PTGYPPFPGYP-------PAGQESSFPPS--GQYPYPSGFPPMGGGAYPQVP--- 50
           PG P P G P   G P       P G +   PP   G    P    P+G    P +P   
Sbjct: 827 PGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKA 886

Query: 51  -SSGYPGAGG---YPAPGGYPAPGGYPG-APQPG--------GAPSYPGVPPGQGFGVPP 97
            +SG+PG  G      P G P P G PG +  PG        G P  PG    +G     
Sbjct: 887 GASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKG---SK 943

Query: 98  GGAGFSGYPQPPSQSYGGGPAQVPLPG--GFPGGQMPSQYPG--GQPTYP 143
           G  G  G P P   +  G   +   PG  G PG   P  Y G  G P  P
Sbjct: 944 GEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQP 993



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 39/111 (35%), Positives = 44/111 (39%), Gaps = 23/111 (20%)

Query: 53  GYPGAGGYPAPGGYPAPGGYPGAPQPGGAP---------SYPGVPPGQGFGVPPGGAGFS 103
           G  G  G+P   G+P   G PG P P G P           PG P  +G   PPG  GF 
Sbjct: 45  GEKGERGFPGLEGHP---GLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101

Query: 104 GYPQPPSQ-SYGGGPAQVPLPG--------GFPG--GQMPSQYPGGQPTYP 143
           G P  P    + G P    +PG        GFPG  G    Q P G P  P
Sbjct: 102 GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIP 152



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 44/133 (33%), Positives = 50/133 (37%), Gaps = 28/133 (21%)

Query: 37  GFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVP-----PGQ 91
           G P   GG   +    G PG  G P   G     G PG P   G P YPG P      GQ
Sbjct: 276 GPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP---GDPGYPGEPGRDGEKGQ 332

Query: 92  -GFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPG--------GFPGGQMPSQYPG----- 137
            G   PPG  G    P+P +    G    + LPG        GFPG Q P   PG     
Sbjct: 333 KGDTGPPGPPGLV-IPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAA 391

Query: 138 -----GQPTYPSQ 145
                G P +P +
Sbjct: 392 VMGPPGPPGFPGE 404



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 51/182 (28%), Positives = 60/182 (32%), Gaps = 44/182 (24%)

Query: 8   PTGYPPFPGYPPAGQESSFP-PSGQYPYPSGFPPMGGGAYPQVPSS-GYPGAGGYP---- 61
           P G P  PG P       FP   G+        P G    P  P + G+PG+ G P    
Sbjct: 492 PPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDIL 551

Query: 62  -------------APGGYPAPG--GYPGAPQPGGAPSYPGVPPG---QGFGVPPGGAGFS 103
                        +PG    PG  G PG     G P   G P G   +G   PPG  G  
Sbjct: 552 TFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLP 611

Query: 104 GYP------QPPS------------QSYGGGPAQ--VPLPGGFPGGQMPSQYPGGQPTYP 143
           G P       PP             Q   G P Q  +P P G PG  +      G P  P
Sbjct: 612 GLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNP 671

Query: 144 SQ 145
            +
Sbjct: 672 GR 673



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 58/206 (28%), Positives = 64/206 (31%), Gaps = 29/206 (14%)

Query: 4    PGYP-------PTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGG--GAYPQVPSSGY 54
            PG P       P G    PG P        P     P   GFP M G  G        G 
Sbjct: 1296 PGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVP---GFPGMKGPSGVPGSAGPEGE 1352

Query: 55   PGAGGYPAPGGYPAPGGY----------PGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSG 104
            PG  G P P G P P G           PG P   G    PG    QG   P G  G  G
Sbjct: 1353 PGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPG 1412

Query: 105  YPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPG--GQPTYPSQINTDSFSSYPVFSPVSL 162
                P     GG    P   G PG +     PG  G    P    T S     V     +
Sbjct: 1413 RNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSS-----VAHGFLI 1467

Query: 163  DYSSEPATVTQVTQGTIRPAANFDAI 188
               S+     Q  QGT++    F  +
Sbjct: 1468 TRHSQTTDAPQCPQGTLQVYEGFSLL 1493



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 39/114 (34%), Positives = 42/114 (36%), Gaps = 14/114 (12%)

Query: 15  PGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPAPGGYPG 74
           PG P    E  FP       P G P   G A       G PG  G+P   G     G PG
Sbjct: 364 PGLPGEKGERGFPG---IQGPPGLPGPPGAAV-----MGPPGPPGFPGERGQKGDEGPPG 415

Query: 75  APQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPGGFPG 128
              P G P   G P   G   PPG AG   +  P  +    GP   P P G PG
Sbjct: 416 ISIP-GPPGLDGQPGAPGLPGPPGPAG--PHIPPSDEICEPGP---PGPPGSPG 463



 Score = 37.4 bits (85), Expect = 0.031
 Identities = 24/64 (37%), Positives = 26/64 (40%), Gaps = 3/64 (4%)

Query: 65  GYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPG 124
           G     G  G P   G P  PG P  +G   P G  G  G P PP      GP  +P   
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLP--- 98

Query: 125 GFPG 128
           GFPG
Sbjct: 99  GFPG 102


>gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens]
          Length = 284

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 56/131 (42%), Positives = 57/131 (43%), Gaps = 20/131 (15%)

Query: 11  YPPFPGYP-PAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGY--PAPGGY- 66
           YP   G P  AGQ    PP   YP P    P  GG Y     SG P  GGY  PAPGG  
Sbjct: 4   YPYRQGCPGAAGQAPGAPPGSYYPGP----PNSGGQY----GSGLPPGGGYGGPAPGGPY 55

Query: 67  --PAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPG 124
             PA GG  G P PG  PS  G P G   G  PGG     Y QPP  SYG     +   G
Sbjct: 56  GPPAGGGPYGHPNPGMFPS--GTPGGPYGGAAPGGP----YGQPPPSSYGAQQPGLYGQG 109

Query: 125 GFPGGQMPSQY 135
           G P    P  Y
Sbjct: 110 GAPPNVDPEAY 120



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 39/91 (42%), Positives = 43/91 (47%), Gaps = 10/91 (10%)

Query: 53  GYPGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQS 112
           G PGA G  APG  P    YPG P  GG     G+PPG G+G P  G  +     PP+  
Sbjct: 9   GCPGAAGQ-APGAPPG-SYYPGPPNSGGQYG-SGLPPGGGYGGPAPGGPYG----PPA-- 59

Query: 113 YGGGPAQVPLPGGFPGGQMPSQYPGGQPTYP 143
            GGGP   P PG FP G     Y G  P  P
Sbjct: 60  -GGGPYGHPNPGMFPSGTPGGPYGGAAPGGP 89



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 42/114 (36%), Positives = 46/114 (40%), Gaps = 30/114 (26%)

Query: 4   PGYPPTGYPPFP---------GYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGY 54
           PG PP  Y P P         G PP G      P G Y      PP GGG Y        
Sbjct: 18  PGAPPGSYYPGPPNSGGQYGSGLPPGGGYGGPAPGGPYG-----PPAGGGPY-------- 64

Query: 55  PGAGGYPAPGGYPAPGGYPGAPQPGGAPSYP-GVPPGQGFGV-PPGGAGFSGYP 106
               G+P PG +P+  G PG P  G AP  P G PP   +G   PG  G  G P
Sbjct: 65  ----GHPNPGMFPS--GTPGGPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAP 112


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 59/158 (37%), Positives = 62/158 (39%), Gaps = 24/158 (15%)

Query: 5   GYPPTGYPPFPGYP----PAG--QESSFPPSGQYPYPSGFPPMGGGAY-----PQVPSSG 53
           G  P G PP PG P    P G  +    PP G+   P G PP GG        P     G
Sbjct: 250 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK---PQGPPPQGGSKSRSSRSPPGKPQG 306

Query: 54  YPGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFS-------GYP 106
            P  GG    G  P PG   G P  GG       PPG+  G PP G   S       G P
Sbjct: 307 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKP 366

Query: 107 QPPSQSYGGGPAQVPLP-GGFPGGQMPSQYPGGQPTYP 143
           Q P Q  G  P   P P GG P  Q P   P GQP  P
Sbjct: 367 QGPPQQEGNNPQGPPPPAGGNP--QQPQAPPAGQPQGP 402



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 60/164 (36%), Positives = 64/164 (39%), Gaps = 29/164 (17%)

Query: 5   GYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPS------SGYPGAG 58
           G PP G P  P  PP G   S         P G PP GG   PQ P        G P  G
Sbjct: 214 GPPPPGKPQGP--PPQGDNKSQSARSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQGPPPQG 270

Query: 59  GYPAPGGYPAPGGYPGAPQPGGA--------PSYPGVPPGQGFGVPPGGAGFSGYPQ-PP 109
           G   P G P PG   G P  GG+        P  P  PP QG   P G     G PQ PP
Sbjct: 271 GNK-PQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 329

Query: 110 SQSYGGGPAQVPLPGGFPGGQMP--------SQYPGGQPTYPSQ 145
            Q  GG   Q P P G P G  P        ++ P G+P  P Q
Sbjct: 330 PQ--GGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQ 371



 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 60/163 (36%), Positives = 65/163 (39%), Gaps = 32/163 (19%)

Query: 5   GYPPTGYPPFPGYPPAGQESSFP--PSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPA 62
           G PP G P  P  PP G +S  P  P G+   P G PP GG   PQ P        G P 
Sbjct: 91  GPPPPGKPQGP--PPQGDKSRSPRSPPGK---PQGPPPQGGNQ-PQGPPPPPGKPQGPPP 144

Query: 63  PGGY----PAPGGYPGAPQPGG---------APSYPGVPPGQGFGVPPGGAGFSGYPQ-P 108
            GG     P P G P  P P G          P  P  PP QG   P G     G PQ P
Sbjct: 145 QGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 204

Query: 109 PSQSYGGGPAQVPLPGGFPGGQMP--------SQYPGGQPTYP 143
           P Q  GG   Q P P G P G  P        ++ P G+P  P
Sbjct: 205 PPQ--GGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGP 245



 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 58/161 (36%), Positives = 60/161 (37%), Gaps = 27/161 (16%)

Query: 5   GYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAPG 64
           G PP G P  P  PP G   S         P G PP GG   PQ P        G P  G
Sbjct: 152 GPPPPGKPQGP--PPQGDNKSRSSRSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQGPPPQG 208

Query: 65  GY----PAPGGYPGAPQPGG---------APSYPGVPPGQGFGVPPGGAGFSGYPQ-PPS 110
           G     P P G P  P P G          P  P  PP QG   P G     G PQ PP 
Sbjct: 209 GNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 268

Query: 111 QSYGGGPAQVPLPGGFPGGQMP--------SQYPGGQPTYP 143
           Q  GG   Q P P G P G  P        S+ P G+P  P
Sbjct: 269 Q--GGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGP 307



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 54/156 (34%), Positives = 57/156 (36%), Gaps = 23/156 (14%)

Query: 5   GYPPTGYPPFPGYP----PAG--QESSFPPSGQYPYPSGFPPMG-----GGAYPQVPSSG 53
           G  P G PP PG P    P G  +    PP G+   P G PP G         P     G
Sbjct: 188 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK---PQGPPPQGDNKSQSARSPPGKPQG 244

Query: 54  YPGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFS-------GYP 106
            P  GG    G  P PG   G P  GG       PPG+  G PP G   S       G P
Sbjct: 245 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKP 304

Query: 107 QPPSQSYGGGPAQVPLPGGFPGGQMP--SQYPGGQP 140
           Q P    G  P   P P G P G  P     P G P
Sbjct: 305 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 340



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 60/152 (39%), Positives = 65/152 (42%), Gaps = 22/152 (14%)

Query: 5   GYPPTGYPPFPGYPPAG---QESSFPPSGQYPYPSGFPPMGGGAYPQVPS------SGYP 55
           G PP G P  P  PP G     SS  P G+   P G PP GG   PQ P        G P
Sbjct: 276 GPPPPGKPQGP--PPQGGSKSRSSRSPPGK---PQGPPPQGGNQ-PQGPPPPPGKPQGPP 329

Query: 56  GAGGYPAPGGYPAPGGYPGAPQPGGAPSYPG-VPPGQGFGVPPGGAGFSGYPQPPSQSYG 114
             GG   P G P PG   G P  GG+ S     PPG+  G PP   G    PQ P    G
Sbjct: 330 PQGGNK-PQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQG-PPQQEG--NNPQGPPPPAG 385

Query: 115 GGPAQVPL-PGGFPGGQMPSQYPGGQPTYPSQ 145
           G P Q    P G P G  P    GG+P+ P Q
Sbjct: 386 GNPQQPQAPPAGQPQGP-PRPPQGGRPSRPPQ 416



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 58/157 (36%), Positives = 61/157 (38%), Gaps = 30/157 (19%)

Query: 8   PTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAPGGY- 66
           P G PP  G  P G  S   P G+   P G PP GG   PQ P        G P  GG  
Sbjct: 36  PQGAPPQGGNKPQGPPS---PPGK---PQGPPPQGGNQ-PQGPPPPPGKPQGPPPQGGNK 88

Query: 67  ---PAPGGYPGAPQPGG--------APSYPGVPPGQGFGVPPGGAGFSGYPQ-PPSQSYG 114
              P P G P  P P G         P  P  PP QG   P G     G PQ PP Q  G
Sbjct: 89  PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ--G 146

Query: 115 GGPAQVPLPGGFPGGQMP--------SQYPGGQPTYP 143
           G   Q P P G P G  P        S+ P G+P  P
Sbjct: 147 GNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGP 183



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 54/156 (34%), Positives = 57/156 (36%), Gaps = 23/156 (14%)

Query: 5   GYPPTGYPPFPGYP----PAG--QESSFPPSGQYPYPSGFPPMG-----GGAYPQVPSSG 53
           G  P G PP PG P    P G  +    PP G+   P G PP G         P     G
Sbjct: 126 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK---PQGPPPQGDNKSRSSRSPPGKPQG 182

Query: 54  YPGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFS-------GYP 106
            P  GG    G  P PG   G P  GG       PPG+  G PP G   S       G P
Sbjct: 183 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKP 242

Query: 107 QPPSQSYGGGPAQVPLPGGFPGGQMP--SQYPGGQP 140
           Q P    G  P   P P G P G  P     P G P
Sbjct: 243 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 278



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 54/158 (34%), Positives = 56/158 (35%), Gaps = 28/158 (17%)

Query: 5   GYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGG--GAYPQVPSSGYPGAGGYPA 62
           G  P G PP PG P        PP G    P G PP G   G  PQ   S  P +     
Sbjct: 65  GNQPQGPPPPPGKPQGP-----PPQGGNK-PQGPPPPGKPQGPPPQGDKSRSPRSPPGKP 118

Query: 63  PGGYPAPGGYP-GAPQPGGAPSYP----------GVPPGQGFGVPPGGAGFS-------G 104
            G  P  G  P G P P G P  P            PPG+  G PP G   S       G
Sbjct: 119 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPG 178

Query: 105 YPQPPSQSYGGGPAQVPLPGGFPGGQMP--SQYPGGQP 140
            PQ P    G  P   P P G P G  P     P G P
Sbjct: 179 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 216



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 40/118 (33%), Positives = 46/118 (38%), Gaps = 22/118 (18%)

Query: 35  PSGFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFG 94
           P G PP GG   PQ P          P+P G P      G  QP G P     PPG+  G
Sbjct: 36  PQGAPPQGGNK-PQGP----------PSPPGKPQGPPPQGGNQPQGPPP----PPGKPQG 80

Query: 95  VPPGGAGFSGYPQPPSQSYG----GGPAQVP-LPGGFPGGQMP--SQYPGGQPTYPSQ 145
            PP G      P PP +  G    G  ++ P  P G P G  P     P G P  P +
Sbjct: 81  PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK 138


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 50/134 (37%), Positives = 55/134 (41%), Gaps = 18/134 (13%)

Query: 4   PGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAP 63
           PG    G PP    PP G   + PP  Q        P G GA      +G+PGA G P P
Sbjct: 830 PGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGA------AGFPGARGLPGP 883

Query: 64  GGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLP 123
              P   G PG P P G+P   G         PPG AG +G P  P  S   G A  P  
Sbjct: 884 ---PGSNGNPGPPGPSGSPGKDG---------PPGPAGNTGAPGSPGVSGPKGDAGQPGE 931

Query: 124 GGFPGGQMPSQYPG 137
            G PG Q P   PG
Sbjct: 932 KGSPGAQGPPGAPG 945



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 57/154 (37%), Positives = 66/154 (42%), Gaps = 33/154 (21%)

Query: 4   PGYPPTGYPPFPGYP------PAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGA 57
           PG P  G P  PG P      P G ++  P    Y   SG   +GG A       GYPG 
Sbjct: 126 PGQP--GSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVA-VGGLA-------GYPGP 175

Query: 58  GGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGP 117
            G P P G P   G+PG+P   G+P Y G PPG+     PG AG SG P PP      GP
Sbjct: 176 AGPPGPPGPPGTSGHPGSP---GSPGYQG-PPGE-----PGQAGPSGPPGPPGAIGPSGP 226

Query: 118 AQVPLPGGFPG--------GQMPSQYPGGQPTYP 143
           A      G PG        G    + P G P +P
Sbjct: 227 AGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFP 260



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 47/128 (36%), Positives = 50/128 (39%), Gaps = 7/128 (5%)

Query: 10  GYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPAP 69
           G P   G P A  E   P       P+G P   G A  +    G PG  G     G P  
Sbjct: 471 GEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGER----GAPGPAGPRGAAGEPGR 526

Query: 70  GGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPGGFPGG 129
            G PG P   G P  PG P   G   PPG  G SG P PP  S   GP   P   GFPG 
Sbjct: 527 DGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPS---GPRGQPGVMGFPGP 583

Query: 130 QMPSQYPG 137
           +     PG
Sbjct: 584 KGNDGAPG 591



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 53/162 (32%), Positives = 59/162 (36%), Gaps = 27/162 (16%)

Query: 4   PGYP----PTGYPPFPGYP-PAGQESSFPPSGQY-----PYPSGFPPMGGGAYPQVPSS- 52
           PG P    P G P   G+P P G + +   +G+      P P G P   G   PQ P   
Sbjct: 563 PGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGP 622

Query: 53  -------------GYPGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGG 99
                        G  G  G P  GG P   G PG P P G    PG P G+G    PG 
Sbjct: 623 TGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGE 682

Query: 100 AGFSGYPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPGGQPT 141
            G  G    P    G GP   P P G  G   P   PG   T
Sbjct: 683 RGPPGLAGAPGLRGGAGP---PGPEGGKGAAGPPGPPGAAGT 721



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 53/149 (35%), Positives = 64/149 (42%), Gaps = 26/149 (17%)

Query: 8   PTGYPPFPGYPPA----GQESSFPPSGQY--PYPSGFP-PMGGGAYPQVPSSGYP-GAGG 59
           P G    PG P A    G++    P+G    P P+G P   G G  P +P    P G+ G
Sbjct: 739 PKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPG 798

Query: 60  YPAPGGYPAPGGYPGAPQPGGAP---SYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGG 116
                G P P G+PGAP   G P      G P  +G G PPG AG      PP    G G
Sbjct: 799 ERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAG------PPG---GSG 849

Query: 117 PAQVPLPGGF------PGGQMPSQYPGGQ 139
           PA  P P G       PGG   + +PG +
Sbjct: 850 PAGPPGPQGVKGERGSPGGPGAAGFPGAR 878



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 52/166 (31%), Positives = 60/166 (36%), Gaps = 14/166 (8%)

Query: 4   PGYPPT-GYPPFPGYP----PAGQESSFPPSGQYPYPSGFPPMG-GGAYPQVPSSGYPGA 57
           PG P T G+P  PG P    P G+     PSG    P    P G  G   +    G PG 
Sbjct: 182 PGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGE 241

Query: 58  GGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGP 117
            G P P G   P G PG P   G   + G    +G    PG  G +G P         GP
Sbjct: 242 RGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGP 301

Query: 118 AQVPLPGGFPG--------GQMPSQYPGGQPTYPSQINTDSFSSYP 155
              P   G PG        G   ++   GQP  P    T  F   P
Sbjct: 302 RGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSP 347



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 50/140 (35%), Positives = 55/140 (39%), Gaps = 11/140 (7%)

Query: 10  GYPPFPGYP-PAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPA 68
           G P  PG   P G       +G  P P+GFP    G   +    G  GA G    GG P 
Sbjct: 783 GAPGLPGIAGPRGSPGERGETGP-PGPAGFPG-APGQNGEPGGKGERGAPGEKGEGGPPG 840

Query: 69  PGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGF---SGYPQPPSQSYGGGPAQVPLPGG 125
             G PG   P G P   GV   +G    PG AGF    G P PP  +   GP   P P G
Sbjct: 841 VAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGP---PGPSG 897

Query: 126 FPGGQMPSQYPG--GQPTYP 143
            PG   P    G  G P  P
Sbjct: 898 SPGKDGPPGPAGNTGAPGSP 917



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 55/172 (31%), Positives = 65/172 (37%), Gaps = 39/172 (22%)

Query: 4   PGYP-PTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGY-------- 54
           PG P P G    PG P    ++  P     P  +G P + GGA P  P  G         
Sbjct: 656 PGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGP 715

Query: 55  PGAGGYPAPGGYP-------APG-----GYPGAPQPGGAPSYPGV--------PPG---- 90
           PGA G P   G P       +PG     G PG P   G P   G         PPG    
Sbjct: 716 PGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQ 775

Query: 91  ---QGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPGGQ 139
              +G G  PG  G +G    P +    GP   P P GFPG    +  PGG+
Sbjct: 776 PGDKGEGGAPGLPGIAGPRGSPGERGETGP---PGPAGFPGAPGQNGEPGGK 824



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 48/139 (34%), Positives = 55/139 (39%), Gaps = 12/139 (8%)

Query: 4    PGYP-PTGYPPFPGYP-PAGQESSFPPSGQY--PYPSGFPPMGGGAYPQVPSSGYPGAGG 59
            PG P P G P   G    +G+  +   SG+   P P G P + G A       G PG  G
Sbjct: 962  PGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTA-------GEPGRDG 1014

Query: 60   YPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQ 119
             P   G P   G PG     G    PG P   G   PPG  G +G      +S   GPA 
Sbjct: 1015 NPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAG 1074

Query: 120  VPLPGGFPGGQMPSQYPGG 138
             P P G  G   P Q P G
Sbjct: 1075 APGPAGSRGAPGP-QGPRG 1092



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 54/173 (31%), Positives = 64/173 (36%), Gaps = 46/173 (26%)

Query: 4   PGYP----PTGYPPFPGY------------------PPAGQESSFPPSGQYPYPSGFPPM 41
           PG P    P G P FPG                   P    E+  P     P P G  P 
Sbjct: 245 PGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMG--PR 302

Query: 42  GG----------GAYPQVPSSGYPGAGGYPAPGGYPAPGGYPGAPQ------PGGAPSYP 85
           G           GA     + G  G+ G P P G P   G+PG+P       P G+P   
Sbjct: 303 GAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSN 362

Query: 86  GVPPGQGFGVPPGGAGFSGYPQPP--SQSYGG----GPAQVPLPGGFPGGQMP 132
           G P  +G   P G AG  G P PP  + S GG    GPA +P   G  G + P
Sbjct: 363 GAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGP 415



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 52/146 (35%), Positives = 55/146 (37%), Gaps = 15/146 (10%)

Query: 4   PGYP-PTGYPPFPGYP-------PAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPS-SGY 54
           PG P P G   FPG P       PAG   S    GQ   P      G    P  P  +G 
Sbjct: 332 PGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGS 391

Query: 55  PGAGGYPAPGGYP-APG--GYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQ 111
           PG  G   P G P APG  G  G P P GA   PG+  G G    PG  G  G P P  +
Sbjct: 392 PGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAG---EPGKNGAKGEPGPRGE 448

Query: 112 SYGGGPAQVPLPGGFPGGQMPSQYPG 137
               G   VP   G  G       PG
Sbjct: 449 RGEAGIPGVPGAKGEDGKDGSPGEPG 474



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 40/117 (34%), Positives = 47/117 (40%), Gaps = 20/117 (17%)

Query: 10  GYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGG-----GAYPQVPSSGYPGAGGYPAPG 64
           G P  PG   A        S   P P G P   G     GA  +V  +G PG+ G P   
Sbjct: 309 GRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQR 368

Query: 65  GYPAPGGYPGAPQPGGAPSYPGVPPGQG----FGVP-----------PGGAGFSGYP 106
           G P P G+ GA  P G P   G P G+G     G+P           PG AG +G P
Sbjct: 369 GEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAP 425



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 48/149 (32%), Positives = 53/149 (35%), Gaps = 12/149 (8%)

Query: 4    PGYP-PTGYPPFPGYP-PAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYP 61
            PG P   G+P   G P P G   +  P G    PSG P   G   P    +G  GA G P
Sbjct: 866  PGGPGAAGFPGARGLPGPPGSNGNPGPPG----PSGSPGKDGPPGP----AGNTGAPGSP 917

Query: 62   APGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVP 121
               G     G PG     GA   PG P   G     G  G +G P  P      GP  V 
Sbjct: 918  GVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVK 977

Query: 122  LPGGFPG--GQMPSQYPGGQPTYPSQINT 148
               G PG  G    + P G    P    T
Sbjct: 978  GESGKPGANGLSGERGPPGPQGLPGLAGT 1006



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 45/131 (34%), Positives = 48/131 (36%), Gaps = 8/131 (6%)

Query: 10  GYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPAP 69
           G P  PG          P S   P P G     G   P  PS    G  G P   G+P P
Sbjct: 528 GVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPS----GPRGQPGVMGFPGP 583

Query: 70  GGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPGGFPGG 129
            G  GAP   G    PG P  QG   PPG  G +G   PP  +  GG      P G P G
Sbjct: 584 KGNDGAPGKNGERGGPGGPGPQG---PPGKNGETGPQGPPGPTGPGGDKGDTGPPG-PQG 639

Query: 130 QMPSQYPGGQP 140
                  GG P
Sbjct: 640 LQGLPGTGGPP 650



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 51/158 (32%), Positives = 55/158 (34%), Gaps = 33/158 (20%)

Query: 8   PTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPS----SGYPGAGGYP-- 61
           P G     G P  G      P G+   P    P G    P  P     +G PG  G P  
Sbjct: 634 PPGPQGLQGLPGTGG-----PPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGL 688

Query: 62  --APG-----GYPAPGGYPGAPQPGGAPSYPGVP-----PGQ--GFGVP--------PGG 99
             APG     G P P G  GA  P G P   G P     PG+  G G P        PGG
Sbjct: 689 AGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGG 748

Query: 100 AGFSGYPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPG 137
            G  G P         GP   P P G PG +     PG
Sbjct: 749 PGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPG 786



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 44/116 (37%), Positives = 47/116 (40%), Gaps = 26/116 (22%)

Query: 39  PPMGGGAYPQVPSSGYPGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPG 98
           PP G G  PQ P        G P P G P   G PG P   G+P  PG PPG     P G
Sbjct: 98  PPNGQG--PQGPK-------GDPGPPGIPGRNGDPGIPGQPGSPGSPG-PPGICESCPTG 147

Query: 99  GAGFSGYPQPPSQSYG-------GGPAQVPLPGGFPGGQMP---SQYPG--GQPTY 142
              +S    P   SY        GG A  P P G PG   P   S +PG  G P Y
Sbjct: 148 PQNYS----PQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGY 199



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 48/164 (29%), Positives = 55/164 (33%), Gaps = 33/164 (20%)

Query: 3   YPGYP-------PTGYPPFPGYPP----------AGQESSFPPSGQYPYPSGFPPMGGGA 45
           +PG P       P G P   G P           AG +    P G    P G   MG   
Sbjct: 343 FPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAG 402

Query: 46  YPQVP----SSGYPG-AGGYPAPG-----GYPAPGGYPGAPQP------GGAPSYPGVPP 89
            P  P    + G PG AG   APG     G P   G  G P P       G P  PG   
Sbjct: 403 IPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKG 462

Query: 90  GQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPGGFPGGQMPS 133
             G    PG  G +G P    +    G      P G PG + P+
Sbjct: 463 EDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPA 506



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 50/157 (31%), Positives = 55/157 (35%), Gaps = 28/157 (17%)

Query: 4    PGYPPTGYPPFPGYP----PAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGG 59
            PG P  G P  PG P    PAG+      SG    P+G P   G       S G PG  G
Sbjct: 1040 PGAP--GAPGHPGPPGPVGPAGKSGDRGESGPAG-PAGAPGPAG-------SRGAPGPQG 1089

Query: 60   YPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQ 119
               P G     G  GA    G   +PG P   G   P G  G  G P P       GP+ 
Sbjct: 1090 ---PRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSG 1146

Query: 120  VPLPGGFPGGQMPSQYPG-----------GQPTYPSQ 145
             P   G  G   P   PG           G P +P Q
Sbjct: 1147 PPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQ 1183



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 46/157 (29%), Positives = 51/157 (32%), Gaps = 30/157 (19%)

Query: 12   PPFP-GYPPAGQESSFPPSGQYPYPSGFP-----PMGGGAYPQVPSSGYPGAGGYPAP-- 63
            PP P G P     +  P     P   G P     P G G   +  S G PGA G+P P  
Sbjct: 994  PPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPG 1053

Query: 64   -------------------GGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSG 104
                                G P P G  GAP P G     G    +G     G  GF G
Sbjct: 1054 PVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPG 1113

Query: 105  YP-QPPSQSYGGGPAQVPLPGGFPGGQMPSQYPGGQP 140
             P  P S    G    +  PG  P G      P G P
Sbjct: 1114 NPGAPGSPGPAGQQGAIGSPG--PAGPRGPVGPSGPP 1148



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 34/97 (35%), Positives = 39/97 (40%), Gaps = 27/97 (27%)

Query: 5    GYPPTGYPPFPGYP-PAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSS--GYPGAGGYP 61
            G+P  G P  PG P PAGQ+ +           G P   G   P  PS   G  G  G+P
Sbjct: 1110 GFP--GNPGAPGSPGPAGQQGAI----------GSPGPAGPRGPVGPSGPPGKDGTSGHP 1157

Query: 62   APGGYPAPGG------------YPGAPQPGGAPSYPG 86
             P G P P G            +PG P P G P  PG
Sbjct: 1158 GPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPG 1194



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 46/144 (31%), Positives = 52/144 (36%), Gaps = 22/144 (15%)

Query: 10   GYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPAP 69
            G+  FPG P  G   S  P+GQ            GA   + S G  G  G   P G P  
Sbjct: 1107 GHRGFPGNP--GAPGSPGPAGQQ-----------GA---IGSPGPAGPRGPVGPSGPPGK 1150

Query: 70   GGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQ----SYGGGPAQVPLPGG 125
             G  G P P G P   G    +G    PG  G  G P PP        G G A +   GG
Sbjct: 1151 DGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGG 1210

Query: 126  FPGGQMPSQYPGGQPTYPSQINTD 149
               G     Y  G      +INTD
Sbjct: 1211 EKAGGFAPYY--GDEPMDFKINTD 1232


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.136    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,491,490
Number of Sequences: 37866
Number of extensions: 1843865
Number of successful extensions: 36206
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 409
Number of HSP's successfully gapped in prelim test: 1146
Number of HSP's that attempted gapping in prelim test: 8778
Number of HSP's gapped (non-prelim): 7854
length of query: 488
length of database: 18,247,518
effective HSP length: 106
effective length of query: 382
effective length of database: 14,233,722
effective search space: 5437281804
effective search space used: 5437281804
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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