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Search of human proteins with 4759198
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4759198 homer 1 [Homo sapiens]
(354 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4759198 homer 1 [Homo sapiens] 696 0.0
gi|46249351 homer 2 isoform 2 [Homo sapiens] 354 6e-98
gi|46249349 homer 2 isoform 1 [Homo sapiens] 346 2e-95
gi|224809414 Homer, neuronal immediate early gene, 3 isoform 1 [... 329 3e-90
gi|224809408 Homer, neuronal immediate early gene, 3 isoform 1 [... 329 3e-90
gi|224809410 Homer, neuronal immediate early gene, 3 isoform 2 [... 321 7e-88
gi|110349797 homer 2 isoform 4 [Homo sapiens] 296 2e-80
gi|110349794 homer 2 isoform 3 [Homo sapiens] 288 5e-78
gi|224809419 Homer, neuronal immediate early gene, 3 isoform 3 [... 278 7e-75
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 64 3e-10
gi|34577114 cytomatrix protein p110 [Homo sapiens] 59 5e-09
gi|56549694 enabled homolog isoform a [Homo sapiens] 59 7e-09
gi|39930375 enabled homolog isoform b [Homo sapiens] 59 7e-09
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 59 7e-09
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 59 9e-09
gi|50083293 coiled-coil domain containing 123 [Homo sapiens] 57 3e-08
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 56 4e-08
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 55 7e-08
gi|71061468 centromere protein E [Homo sapiens] 55 7e-08
gi|110611218 ribosome binding protein 1 [Homo sapiens] 55 1e-07
gi|110611220 ribosome binding protein 1 [Homo sapiens] 55 1e-07
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 55 1e-07
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 55 1e-07
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 55 1e-07
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens] 55 1e-07
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 54 3e-07
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 54 3e-07
gi|21735548 centrosomal protein 2 [Homo sapiens] 54 3e-07
gi|62243374 MAD1-like 1 protein [Homo sapiens] 53 5e-07
gi|62243369 MAD1-like 1 protein [Homo sapiens] 53 5e-07
>gi|4759198 homer 1 [Homo sapiens]
Length = 354
Score = 696 bits (1797), Expect = 0.0
Identities = 354/354 (100%), Positives = 354/354 (100%)
Query: 1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINST 60
MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINST
Sbjct: 1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINST 60
Query: 61 ITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEK 120
ITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEK
Sbjct: 61 ITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEK 120
Query: 121 MELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRAEPTQNALPFSHSSAIS 180
MELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRAEPTQNALPFSHSSAIS
Sbjct: 121 MELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRAEPTQNALPFSHSSAIS 180
Query: 181 KHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQAN 240
KHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQAN
Sbjct: 181 KHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQAN 240
Query: 241 AVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKD 300
AVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKD
Sbjct: 241 AVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKD 300
Query: 301 LEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLECS 354
LEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLECS
Sbjct: 301 LEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLECS 354
>gi|46249351 homer 2 isoform 2 [Homo sapiens]
Length = 354
Score = 354 bits (909), Expect = 6e-98
Identities = 186/351 (52%), Positives = 252/351 (71%), Gaps = 2/351 (0%)
Query: 1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINST 60
MGEQPIF+TRAHVFQIDPNTKKNW+P SK AVTVSYFYD TRN YRIIS+DG+K IINST
Sbjct: 1 MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINST 60
Query: 61 ITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEK 120
ITPNMTFTKTSQKFGQWADSRANTV+GLGFSSE L+KFAEKFQE KEAA++AK+K+QEK
Sbjct: 61 ITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEK 120
Query: 121 MELTSTPSQESAGGDLQSPLTPESINGTDDERTPDV-TQNSEPRAEPTQNALPFSHSSAI 179
+E +S SQES G + S S+NGTDDE+ N+ ++E + + + S+A
Sbjct: 121 IETSSNHSQES-GRETPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAAN 179
Query: 180 SKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQA 239
K WE EL TL+ +NA+LT AL ES A+V+QWK+Q + ++E +RL ++ ELE S+
Sbjct: 180 VKKWEIELQTLRESNARLTTALQESAASVEQWKRQFSICRDENDRLRNKIDELEEQCSEI 239
Query: 240 NAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNK 299
N T+L + I+ELE L+ KE E++ L+++ + +L + + +++KL+ E N+
Sbjct: 240 NREKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQ 299
Query: 300 DLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKL 350
+LE ++ L+ +E+S+ Q + LK+ LE+LDGKI +L + R L+KL
Sbjct: 300 NLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKL 350
>gi|46249349 homer 2 isoform 1 [Homo sapiens]
Length = 343
Score = 346 bits (888), Expect = 2e-95
Identities = 183/351 (52%), Positives = 248/351 (70%), Gaps = 13/351 (3%)
Query: 1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINST 60
MGEQPIF+TRAHVFQIDPNTKKNW+P SK AVTVSYFYD TRN YRIIS+DG+K IINST
Sbjct: 1 MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINST 60
Query: 61 ITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEK 120
ITPNMTFTKTSQKFGQWADSRANTV+GLGFSSE L+KFAEKFQE KEAA++AK+K+QEK
Sbjct: 61 ITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEK 120
Query: 121 MELTSTPSQESAGGDLQSPLTPESINGTDDERTPDV-TQNSEPRAEPTQNALPFSHSSAI 179
+E +S SQ S S+NGTDDE+ N+ ++E + + + S+A
Sbjct: 121 IETSSNHSQAS------------SVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAAN 168
Query: 180 SKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQA 239
K WE EL TL+ +NA+LT AL ES A+V+QWK+Q + ++E +RL ++ ELE S+
Sbjct: 169 VKKWEIELQTLRESNARLTTALQESAASVEQWKRQFSICRDENDRLRNKIDELEEQCSEI 228
Query: 240 NAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNK 299
N T+L + I+ELE L+ KE E++ L+++ + +L + + +++KL+ E N+
Sbjct: 229 NREKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQ 288
Query: 300 DLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKL 350
+LE ++ L+ +E+S+ Q + LK+ LE+LDGKI +L + R L+KL
Sbjct: 289 NLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKL 339
>gi|224809414 Homer, neuronal immediate early gene, 3 isoform 1
[Homo sapiens]
Length = 361
Score = 329 bits (843), Expect = 3e-90
Identities = 185/359 (51%), Positives = 240/359 (66%), Gaps = 11/359 (3%)
Query: 3 EQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTIT 62
EQPIFSTRAHVFQIDP TK+NW+P KHA+TVSYFYD+TRNVYRIIS+ G+KAIINST+T
Sbjct: 6 EQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAIINSTVT 65
Query: 63 PNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKME 122
PNMTFTKTSQKFGQWADSRANTVYGLGF+SE HL++FAEKFQE KEAARLA+EKSQ+ E
Sbjct: 66 PNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQFAEKFQEVKEAARLAREKSQDGGE 125
Query: 123 LTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRAEPTQN---ALPFSHSSAI 179
LTS ++ SPL S NG +E+ S PT+ S S
Sbjct: 126 LTSPALGLASHQVPPSPLV--SANGPGEEKL--FRSQSADAPGPTERERLKKMLSEGSVG 181
Query: 180 SKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQA 239
WEAE L+ +N KL AL E+ A QW+QQL A + EAERL +RV ELE ++
Sbjct: 182 EVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASE 241
Query: 240 NAVHTHKTEL--NQTIQELEETLKLKEEEIERLKQEIDNARELQE--QRDSLTQKLQEVE 295
K L Q++++LE ++ K++EI+ LK + RE E +R+ QK+Q++E
Sbjct: 242 VTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLE 301
Query: 296 IRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLECS 354
RN +LE QL +E+ LE+++ E+E R + ++LD +FEL+ELR+ LA+L E +
Sbjct: 302 TRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEAA 360
>gi|224809408 Homer, neuronal immediate early gene, 3 isoform 1
[Homo sapiens]
Length = 361
Score = 329 bits (843), Expect = 3e-90
Identities = 185/359 (51%), Positives = 240/359 (66%), Gaps = 11/359 (3%)
Query: 3 EQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTIT 62
EQPIFSTRAHVFQIDP TK+NW+P KHA+TVSYFYD+TRNVYRIIS+ G+KAIINST+T
Sbjct: 6 EQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAIINSTVT 65
Query: 63 PNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKME 122
PNMTFTKTSQKFGQWADSRANTVYGLGF+SE HL++FAEKFQE KEAARLA+EKSQ+ E
Sbjct: 66 PNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQFAEKFQEVKEAARLAREKSQDGGE 125
Query: 123 LTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRAEPTQN---ALPFSHSSAI 179
LTS ++ SPL S NG +E+ S PT+ S S
Sbjct: 126 LTSPALGLASHQVPPSPLV--SANGPGEEKL--FRSQSADAPGPTERERLKKMLSEGSVG 181
Query: 180 SKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQA 239
WEAE L+ +N KL AL E+ A QW+QQL A + EAERL +RV ELE ++
Sbjct: 182 EVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASE 241
Query: 240 NAVHTHKTEL--NQTIQELEETLKLKEEEIERLKQEIDNARELQE--QRDSLTQKLQEVE 295
K L Q++++LE ++ K++EI+ LK + RE E +R+ QK+Q++E
Sbjct: 242 VTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLE 301
Query: 296 IRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLECS 354
RN +LE QL +E+ LE+++ E+E R + ++LD +FEL+ELR+ LA+L E +
Sbjct: 302 TRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEAA 360
>gi|224809410 Homer, neuronal immediate early gene, 3 isoform 2
[Homo sapiens]
Length = 358
Score = 321 bits (822), Expect = 7e-88
Identities = 182/357 (50%), Positives = 236/357 (66%), Gaps = 10/357 (2%)
Query: 3 EQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTIT 62
EQPIFSTRAHVFQIDP TK+NW+P KHA+TVSYFYD+TRNVYRIIS+ G+KAIINST+T
Sbjct: 6 EQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAIINSTVT 65
Query: 63 PNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKME 122
PNMTFTKTSQKFGQWADSRANTVYGLGF+SE HL++FAEKFQE KEAARLA+EKSQ+ E
Sbjct: 66 PNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQFAEKFQEVKEAARLAREKSQDGGE 125
Query: 123 LTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRAEPTQN---ALPFSHSSAI 179
LTS ++ SPL S NG +E+ S PT+ S S
Sbjct: 126 LTSPALGLASHQVPPSPLV--SANGPGEEKL--FRSQSADAPGPTERERLKKMLSEGSVG 181
Query: 180 SKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQA 239
WEAE L+ +N KL AL E+ A QW+QQL A + EAERL +RV ELE ++
Sbjct: 182 EVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASE 241
Query: 240 NAVHTHKTEL--NQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIR 297
K L Q++++LE ++ K++EI+ LK + RE E + + Q+V+ R
Sbjct: 242 VTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAER-EETQQKVQTR 300
Query: 298 NKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLECS 354
N +LE QL +E+ LE+++ E+E R + ++LD +FEL+ELR+ LA+L E +
Sbjct: 301 NAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEAA 357
>gi|110349797 homer 2 isoform 4 [Homo sapiens]
Length = 299
Score = 296 bits (758), Expect = 2e-80
Identities = 169/350 (48%), Positives = 220/350 (62%), Gaps = 55/350 (15%)
Query: 1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINST 60
MGEQPIF+TRAHVFQIDPNTKKNW+P SK AVTVSYFYD TRN YRIIS+DG+K IINST
Sbjct: 1 MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINST 60
Query: 61 ITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEK 120
ITPNMTFTKTSQKFGQWADSRANTV+GLGFSSE L+KFAEKFQE KEAA++AK+K+QEK
Sbjct: 61 ITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEK 120
Query: 121 MELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRAEPTQNALPFSHSSAIS 180
+E +S SQES G + S S+NGTDDE+ SH+ +
Sbjct: 121 IETSSNHSQES-GRETPSSTQASSVNGTDDEKA--------------------SHAGPAN 159
Query: 181 KHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQAN 240
H LK N KL AL +S ANVK ++ N
Sbjct: 160 TH-------LKSENDKLKIALTQSAANVK---------------------------NEIN 185
Query: 241 AVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKD 300
T+L + I+ELE L+ KE E++ L+++ + +L + + +++KL+ E N++
Sbjct: 186 REKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQN 245
Query: 301 LEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKL 350
LE ++ L+ +E+S+ Q + LK+ LE+LDGKI +L + R L+KL
Sbjct: 246 LEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKL 295
>gi|110349794 homer 2 isoform 3 [Homo sapiens]
Length = 288
Score = 288 bits (737), Expect = 5e-78
Identities = 166/350 (47%), Positives = 216/350 (61%), Gaps = 66/350 (18%)
Query: 1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINST 60
MGEQPIF+TRAHVFQIDPNTKKNW+P SK AVTVSYFYD TRN YRIIS+DG+K IINST
Sbjct: 1 MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINST 60
Query: 61 ITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEK 120
ITPNMTFTKTSQKFGQWADSRANTV+GLGFSSE L+KFAEKFQE KEAA++AK+K+QEK
Sbjct: 61 ITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEK 120
Query: 121 MELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRAEPTQNALPFSHSSAIS 180
+E +S SQ S S+NGTDDE+ SH+ +
Sbjct: 121 IETSSNHSQAS------------SVNGTDDEKA--------------------SHAGPAN 148
Query: 181 KHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQAN 240
H LK N KL AL +S ANVK ++ N
Sbjct: 149 TH-------LKSENDKLKIALTQSAANVK---------------------------NEIN 174
Query: 241 AVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKD 300
T+L + I+ELE L+ KE E++ L+++ + +L + + +++KL+ E N++
Sbjct: 175 REKEKNTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQN 234
Query: 301 LEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKL 350
LE ++ L+ +E+S+ Q + LK+ LE+LDGKI +L + R L+KL
Sbjct: 235 LEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKL 284
>gi|224809419 Homer, neuronal immediate early gene, 3 isoform 3
[Homo sapiens]
Length = 325
Score = 278 bits (710), Expect = 7e-75
Identities = 165/359 (45%), Positives = 214/359 (59%), Gaps = 47/359 (13%)
Query: 3 EQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTIT 62
EQPIFSTRAHVFQIDP TK+NW+P KHA+TVSYFYD+TRNVYRIIS+ G+KAIINST+T
Sbjct: 6 EQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAIINSTVT 65
Query: 63 PNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKME 122
PNMTFTKTSQKFGQWADSRANTVYGLGF+SE H
Sbjct: 66 PNMTFTKTSQKFGQWADSRANTVYGLGFASEQH--------------------------- 98
Query: 123 LTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRAEPTQN---ALPFSHSSAI 179
LT P SPL S NG +E+ S PT+ S S
Sbjct: 99 LTQVP---------PSPLV--SANGPGEEKL--FRSQSADAPGPTERERLKKMLSEGSVG 145
Query: 180 SKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQA 239
WEAE L+ +N KL AL E+ A QW+QQL A + EAERL +RV ELE ++
Sbjct: 146 EVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASE 205
Query: 240 NAVHTHKTEL--NQTIQELEETLKLKEEEIERLKQEIDNARELQE--QRDSLTQKLQEVE 295
K L Q++++LE ++ K++EI+ LK + RE E +R+ QK+Q++E
Sbjct: 206 VTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLE 265
Query: 296 IRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLECS 354
RN +LE QL +E+ LE+++ E+E R + ++LD +FEL+ELR+ LA+L E +
Sbjct: 266 TRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEAA 324
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 63.5 bits (153), Expect = 3e-10
Identities = 66/253 (26%), Positives = 110/253 (43%), Gaps = 18/253 (7%)
Query: 79 DSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKMELTS-TPSQESAGGDLQ 137
D V L E +S+F E L +EK+ E M+L + E ++
Sbjct: 2017 DDLQKQVKALEIDVEEQVSRFIE----------LEQEKNTELMDLRQQNQALEKQLEKMR 2066
Query: 138 SPLTPESINGTDDERTPDVTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKL 197
L ++I D E DV Q + E +P IS+H E+ L + +
Sbjct: 2067 KFLDEQAI---DREHERDVFQQEIQKLEQQLKVVP--RFQPISEHQTREVEQLANHLKEK 2121
Query: 198 TAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELE 257
T E + +Q ++ + EE E+L RV ELE + H E + LE
Sbjct: 2122 TDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVEDRKHFGAVEAKPELS-LE 2180
Query: 258 ETLKLKEEEIERLKQEIDNARELQEQ-RDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQ 316
L+ + + I+R ++EI N E EQ R+ L K +EV+ + LE Q + RL++ +
Sbjct: 2181 VQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELE 2240
Query: 317 NEQEAFRNNLKTL 329
E + F+++++ L
Sbjct: 2241 QENKLFKDDMEKL 2253
Score = 50.8 bits (120), Expect = 2e-06
Identities = 39/146 (26%), Positives = 72/146 (49%), Gaps = 1/146 (0%)
Query: 207 NVKQWKQQLAAYQEEAERLHKRVTEL-ECVSSQANAVHTHKTELNQTIQELEETLKLKEE 265
N++Q + Q+ Q E + R TEL E +SS+ V K+EL QT ELE TLK + +
Sbjct: 3117 NIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHK 3176
Query: 266 EIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNN 325
++ L+ ++ ++ L L + ++++L+ L + +L +S+ + +
Sbjct: 3177 HLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELED 3236
Query: 326 LKTLLEILDGKIFELTELRDNLAKLL 351
LK LE + +L L + +LL
Sbjct: 3237 LKFSLESQKQRNLQLNLLLEQQKQLL 3262
Score = 49.7 bits (117), Expect = 4e-06
Identities = 44/192 (22%), Positives = 99/192 (51%), Gaps = 28/192 (14%)
Query: 156 VTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQL 215
+ ++ E E + L FSH E EL+ LK + +E N+++ K L
Sbjct: 614 MAESQEAELERLRTQLLFSH--------EEELSKLKEDLE------IEHRINIEKLKDNL 659
Query: 216 AA-YQEEAERLHKRVTE-LECVSSQANAVHTHKTELNQTIQELEET----LKLKEEE--- 266
Y+++ + L +++ +E + + + + T + +L I +L++ + K EE
Sbjct: 660 GIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTL 719
Query: 267 -IERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQL----SDLEQRLEKSQNEQEA 321
I L++EI+ R+ ++++ +L Q++QE++++ + LE Q+ +DL+++ + + E
Sbjct: 720 QINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSI 779
Query: 322 FRNNLKTLLEIL 333
++ KTL ++L
Sbjct: 780 LKDEKKTLEDML 791
Score = 46.2 bits (108), Expect = 4e-05
Identities = 69/318 (21%), Positives = 125/318 (39%), Gaps = 43/318 (13%)
Query: 39 DSTRNVYRIISLDGSKAI-INSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLS 97
D V R I L+ K + N K +K ++ D +A EH
Sbjct: 2029 DVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQA-------IDREHERD 2081
Query: 98 KFAEKFQEFKEAARLA------KEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDE 151
F ++ Q+ ++ ++ E ++E + +E + L+ E + E
Sbjct: 2082 VFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQE 2141
Query: 152 RTPDVTQNSEPRAEPTQNALPFS---HSSAISKHWEAELATLKGNNAKLTA---ALLEST 205
R ++ + E R + AL H A+ E L +L A A+
Sbjct: 2142 RNEEI-EKLEFRVRELEQALLVEDRKHFGAVEAKPELSL------EVQLQAERDAIDRKE 2194
Query: 206 ANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEE 265
+ ++QL ++EE E ++ V +L + K E +QELE+ KL ++
Sbjct: 2195 KEITNLEEQLEQFREELENKNEEVQQLHM------QLEIQKKESTTRLQELEQENKLFKD 2248
Query: 266 EIERLKQEI--DNARELQEQR---DSLTQKLQEVEIRNKDLEGQLSDLEQRLE-----KS 315
++E+L I +A Q+Q Q +QE E+ L Q++ L+Q+L+ K
Sbjct: 2249 DMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKV 2308
Query: 316 QNEQEAFRNNLKTLLEIL 333
E+ +L+T +E L
Sbjct: 2309 IEEKNELIRDLETQIECL 2326
Score = 42.4 bits (98), Expect = 6e-04
Identities = 37/147 (25%), Positives = 77/147 (52%), Gaps = 17/147 (11%)
Query: 203 ESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKL 262
EST +++ +Q+ ++++ E+L + E + +S+Q H + Q IQE
Sbjct: 2231 ESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQ--HVLFGKFAQIIQE------- 2281
Query: 263 KEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAF 322
KE EI++L +++ +LQ+Q +T + +E +N+ + DLE ++E ++QE
Sbjct: 2282 KEVEIDQLNEQV---TKLQQQL-KITTDNKVIEEKNE----LIRDLETQIECLMSDQECV 2333
Query: 323 RNNLKTLLEILDGKIFELTELRDNLAK 349
+ N + +E L+ I +L + N+ +
Sbjct: 2334 KRNREEEIEQLNEVIEKLQQELANIGQ 2360
Score = 38.5 bits (88), Expect = 0.009
Identities = 41/192 (21%), Positives = 83/192 (43%), Gaps = 22/192 (11%)
Query: 165 EPTQNALPFSHSSAISKHWEAELATLKGNNAKL-------TAALLESTANVKQWKQQLAA 217
+P L + SS + E L + +++L T + ES ++ + L
Sbjct: 1836 DPENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKC 1895
Query: 218 YQEEAERLHKR-------VTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEI--- 267
+E ERLH+ EL + KT + IQE + + E+E+
Sbjct: 1896 QEELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCA 1955
Query: 268 -ERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKS----QNEQEAF 322
RL++ +++QE+R+ L+++ + ++ +E QL ++L K Q + E
Sbjct: 1956 SNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKV 2015
Query: 323 RNNLKTLLEILD 334
R++L+ ++ L+
Sbjct: 2016 RDDLQKQVKALE 2027
Score = 38.1 bits (87), Expect = 0.012
Identities = 33/144 (22%), Positives = 61/144 (42%), Gaps = 7/144 (4%)
Query: 191 KGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELN 250
KG + T N Q K A E +L ++ E + + + K L
Sbjct: 468 KGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQ 527
Query: 251 QTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQ 310
+ +++L E L E+I+R +Q I E + + + + L VE DL+ ++ +
Sbjct: 528 RQLEDLVEELSFSREQIQRARQTI---AEQESKLNEAHKSLSTVE----DLKAEIVSASE 580
Query: 311 RLEKSQNEQEAFRNNLKTLLEILD 334
++ + + EA N K LE+L+
Sbjct: 581 SRKELELKHEAEVTNYKIKLEMLE 604
Score = 37.4 bits (85), Expect = 0.021
Identities = 33/148 (22%), Positives = 76/148 (51%), Gaps = 13/148 (8%)
Query: 212 KQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLK 271
K+++ + E L+ ++ E E + + T ++ + EL+E + K +EI+ +K
Sbjct: 321 KEEIQEKETIIEELNTKIIEEE---KKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMK 377
Query: 272 QEIDNARELQEQRDSLTQKL----QEVEIRNKDLEGQLSDLEQRLE-KSQNEQEAFRNNL 326
E+ N+++ + Q ++L +E++ RN +D+ QR+E ++Q + E R L
Sbjct: 378 LELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAEL 437
Query: 327 KTLLEILDGKIFELTE--LRDNLAKLLE 352
E+ +I ++ + +R ++A++ E
Sbjct: 438 D---EMYGQQIVQMKQELIRQHMAQMEE 462
Score = 37.0 bits (84), Expect = 0.027
Identities = 58/253 (22%), Positives = 108/253 (42%), Gaps = 38/253 (15%)
Query: 107 KEAARLAKEKSQEKMELT----STPSQESAGGDL------QSPLTPESINGTDDERTPDV 156
KE A+L + + ++K EL S SQ+ L Q L ES + +R
Sbjct: 3218 KEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYD 3277
Query: 157 TQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQ---WKQ 213
Q SE + + + + + L + +A+L ++ + T + +
Sbjct: 3278 AQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSS--DGTGQSRPPLPSED 3335
Query: 214 QLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEE-------TLKLKEE- 265
L Q++ E H R+ EL N +K + QT Q++E+ TL+ ++E
Sbjct: 3336 LLKELQKQLEEKHSRIVEL------LNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEA 3389
Query: 266 --EIERLKQEIDN-ARELQEQRDSLTQKLQEVEIRNKDLEGQ-LSDLEQRLEKSQNEQEA 321
E ++ E+ + +LQ Q + Q++ ++ DLEGQ L + Q +K + E+E
Sbjct: 3390 NTEGQKKMHELQSKVEDLQRQLEEKRQQVYKL-----DLEGQRLQGIMQEFQKQELEREE 3444
Query: 322 FRNNLKTLLEILD 334
R + + L + L+
Sbjct: 3445 KRESRRILYQNLN 3457
Score = 36.2 bits (82), Expect = 0.046
Identities = 40/191 (20%), Positives = 83/191 (43%), Gaps = 35/191 (18%)
Query: 181 KHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQAN 240
+ +EA + G +LTA L ++ + ++ E++++L + +L+ + N
Sbjct: 194 QEFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQLQASETLRN 253
Query: 241 AVH---------------THKTELNQTIQELEETLKLKEE---------------EIERL 270
+ H TH+ +L + LE+ K KE+ E+E+
Sbjct: 254 STHSSTAADLLQAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQD 313
Query: 271 KQ-EIDNARELQEQR---DSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNL 326
K+ E N E+QE+ + L K+ E E + +L+ +L+ ++ L + Q + +
Sbjct: 314 KKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEI 373
Query: 327 KTL-LEILDGK 336
K + LE+ + K
Sbjct: 374 KNMKLELTNSK 384
Score = 35.8 bits (81), Expect = 0.060
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 13/91 (14%)
Query: 212 KQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLK 271
K +A E E + K TEL + K EL+Q + +L E LK K EI L
Sbjct: 921 KTFVAETLEMGEVVEKDTTEL---MEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLN 977
Query: 272 QEIDNARELQEQRDSLTQKLQEVEIRNKDLE 302
+E+ SL Q+ ++V +R ++LE
Sbjct: 978 EEVK----------SLKQEKEQVSLRCRELE 998
Score = 35.4 bits (80), Expect = 0.078
Identities = 26/123 (21%), Positives = 60/123 (48%), Gaps = 10/123 (8%)
Query: 208 VKQWKQQLAAYQEEAERLHKRVTE----LECVSSQANAVHTHKTELNQTIQELEETLKLK 263
++ ++ ++ +QE L +VTE L + ++ + + +T+ ++ EE L +
Sbjct: 1242 LQDYRYEVQDFQENMHTLLNKVTEEYNKLLVLQTRLSKIWGQQTD-GMKLEFGEENLPKE 1300
Query: 264 EEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRN-----KDLEGQLSDLEQRLEKSQNE 318
E E + ++ N ++ S LQ++E ++LE +S L+Q+L++++
Sbjct: 1301 ETEFLSIHSQMTNLEDIDVNHKSKLSSLQDLEKTKLEEQVQELESLISSLQQQLKETEQN 1360
Query: 319 QEA 321
EA
Sbjct: 1361 YEA 1363
Score = 34.7 bits (78), Expect = 0.13
Identities = 34/137 (24%), Positives = 64/137 (46%), Gaps = 19/137 (13%)
Query: 213 QQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQ 272
Q+L A Q++ + E E +S Q A+ + Q Q L+ET KL +E++E Q
Sbjct: 1960 QELEAEQQQIQE------ERELLSRQKEAMKAEAGPVEQ--QLLQETEKLMKEKLEVQCQ 2011
Query: 273 EIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQ----RLEKSQNEQEAFRNNLKT 328
++ RD L ++++ +EI ++ + +LEQ L + + +A L+
Sbjct: 2012 A-------EKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEK 2064
Query: 329 LLEILDGKIFELTELRD 345
+ + LD + + RD
Sbjct: 2065 MRKFLDEQAIDREHERD 2081
Score = 34.3 bits (77), Expect = 0.17
Identities = 60/254 (23%), Positives = 105/254 (41%), Gaps = 31/254 (12%)
Query: 104 QEFKEAARLAKE--KSQEKMELTSTPSQESAGGDLQ---SPLTPESINGTDDERT-PDVT 157
QE KE L +E + Q K EL +E DLQ + L E+ D+++T D+
Sbjct: 733 QEEKEKGTLEQEVQELQLKTELLEKQMKEKEN-DLQEKFAQLEAENSILKDEKKTLEDML 791
Query: 158 QNSEPRAEPTQNA-LPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANV-------- 208
+ P ++ + L S + WE E+ L N L ++ +
Sbjct: 792 KIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFS 851
Query: 209 ---KQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELE------ET 259
K ++ QEE L K +LE S+ +K++L +EL T
Sbjct: 852 FAEKNFEVNYQELQEEYACLLKVKDDLE--DSKNKQELEYKSKLKALNEELHLQRINPTT 909
Query: 260 LKLKEEEIERLKQEIDNARELQE--QRDS--LTQKLQEVEIRNKDLEGQLSDLEQRLEKS 315
+K+K + K + E+ E ++D+ L +KL+ + +L +LSDL ++L++
Sbjct: 910 VKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQK 969
Query: 316 QNEQEAFRNNLKTL 329
E +K+L
Sbjct: 970 HGEISFLNEEVKSL 983
Score = 33.9 bits (76), Expect = 0.23
Identities = 28/131 (21%), Positives = 57/131 (43%), Gaps = 1/131 (0%)
Query: 219 QEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNAR 278
QE +L + EL+ + Q V + + Q + ++EE + E+E + N
Sbjct: 424 QETQRKLEQLRAELDEMYGQ-QIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNIT 482
Query: 279 ELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIF 338
++Q + + E+ I+ +D Q L++ L E+ A + L+ L+E L
Sbjct: 483 VNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSRE 542
Query: 339 ELTELRDNLAK 349
++ R +A+
Sbjct: 543 QIQRARQTIAE 553
Score = 32.7 bits (73), Expect = 0.51
Identities = 25/81 (30%), Positives = 45/81 (55%), Gaps = 7/81 (8%)
Query: 248 ELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSD 307
E++ + + L L EE++E ++QE+ R+ QE + + T+ L++ +R +E Q D
Sbjct: 1568 EISVSSMDASRQLMLNEEQLEDMRQEL--VRQYQEHQQA-TELLRQAHMR--QMERQRED 1622
Query: 308 LEQRLE--KSQNEQEAFRNNL 326
EQ E K N Q A R+++
Sbjct: 1623 QEQLQEEIKRLNRQLAQRSSI 1643
Score = 32.3 bits (72), Expect = 0.66
Identities = 26/125 (20%), Positives = 54/125 (43%), Gaps = 5/125 (4%)
Query: 191 KGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELN 250
K + + + L+ V + +Q E + ++ T +E ++++ EL
Sbjct: 290 KKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELK 349
Query: 251 QTIQELEETLKLKEEEIERLKQEIDNAR-ELQEQRDSLTQKLQEVEIRNKDLEGQLSDLE 309
+ ++ L +E+I + QEI N + EL + Q +E+ K L G + +L+
Sbjct: 350 DKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEI----KQLMGTVEELQ 405
Query: 310 QRLEK 314
+R K
Sbjct: 406 KRNHK 410
Score = 32.3 bits (72), Expect = 0.66
Identities = 41/169 (24%), Positives = 79/169 (46%), Gaps = 8/169 (4%)
Query: 184 EAELATLKGNNAKLTAALLESTANVK-QWKQQLAAYQEEAERLHKRVTELECVSSQANA- 241
++E TL+ N + +L K +Q++ Q + E L K++ E E + A
Sbjct: 713 KSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQ 772
Query: 242 VHTHKTELNQTIQELEETLKLKE--EEIERLKQEIDNARELQEQRDSLTQKLQEVEIR-N 298
+ + L + LE+ LK+ + ERL +D+ + + +DS+ +K E+ I N
Sbjct: 773 LEAENSILKDEKKTLEDMLKIHTPVSQEERLIF-LDSIKS--KSKDSVWEKEIEILIEEN 829
Query: 299 KDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNL 347
+DL+ Q L + +EK +N N + + L + L +++D+L
Sbjct: 830 EDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDL 878
Score = 32.3 bits (72), Expect = 0.66
Identities = 27/117 (23%), Positives = 59/117 (50%), Gaps = 6/117 (5%)
Query: 219 QEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNAR 278
QEE +RL++++ + + ++ N V + L ++ELE +L E+L E+ N+
Sbjct: 1627 QEEIKRLNRQLAQRSSIDNE-NLVSERERVL---LEELEALKQLSLAGREKLCCELRNSS 1682
Query: 279 ELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNE--QEAFRNNLKTLLEIL 333
+ + +++E + K+L+ + D+ + ++ Q+A LK LLE++
Sbjct: 1683 TQTQNGNENQGEVEEQTFKEKELDRKPEDVPPEILSNERYALQKANNRLLKILLEVV 1739
Score = 32.3 bits (72), Expect = 0.66
Identities = 21/88 (23%), Positives = 43/88 (48%), Gaps = 3/88 (3%)
Query: 231 ELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARE-LQEQRD--SL 287
ELE + +++ A + ++L+E L +KE + L++++ R+ L E ++ S+
Sbjct: 2682 ELEALRAESVATKAELASYKEKAEKLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLSI 2741
Query: 288 TQKLQEVEIRNKDLEGQLSDLEQRLEKS 315
+K E E++ L +L KS
Sbjct: 2742 LEKEDETEVQESKKACMFEPLPIKLSKS 2769
Score = 32.0 bits (71), Expect = 0.86
Identities = 30/121 (24%), Positives = 60/121 (49%), Gaps = 12/121 (9%)
Query: 202 LESTANVKQ--WKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEET 259
LE + N ++ +K +L A EE LH + V +++ KT + +T++ E
Sbjct: 878 LEDSKNKQELEYKSKLKALNEE---LHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVV 934
Query: 260 LKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQ 319
K E +E+L E+ +L+ L+Q+L ++ + K G++S L + ++ + E+
Sbjct: 935 EKDTTELMEKL--EVTKREKLE-----LSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEK 987
Query: 320 E 320
E
Sbjct: 988 E 988
Score = 31.2 bits (69), Expect = 1.5
Identities = 36/183 (19%), Positives = 77/183 (42%), Gaps = 23/183 (12%)
Query: 186 ELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTH 245
E L+ L L S +++ +Q +A + + HK ++ +E + ++ +
Sbjct: 522 EKCALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASES 581
Query: 246 KTELNQTIQELEETLKLKEEEIERLKQEI-DNARELQE-------------QRDSLTQKL 291
+ EL + K+K E +E+ K + D E QE + L++
Sbjct: 582 RKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLK 641
Query: 292 QEVEIRNKDLEGQLSD-----LEQRLEKSQNEQ----EAFRNNLKTLLEILDGKIFELTE 342
+++EI ++ +L D +Q+++ QNE E + L+ + I E+++
Sbjct: 642 EDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISK 701
Query: 343 LRD 345
L+D
Sbjct: 702 LKD 704
Score = 31.2 bits (69), Expect = 1.5
Identities = 33/160 (20%), Positives = 63/160 (39%), Gaps = 26/160 (16%)
Query: 134 GDLQSPLTPESINGTDDERTPD-VTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKG 192
G+ +P +N D E + D +++N +P + + + E L
Sbjct: 1211 GEYYTPALKCEVNAEDKENSGDYISENEDPELQ--------DYRYEVQDFQENMHTLLNK 1262
Query: 193 NNAKLTAALLESTANVKQWKQQLAAYQ----------EEAERL--HKRVTELECV----- 235
+ L+ T K W QQ + EE E L H ++T LE +
Sbjct: 1263 VTEEYNKLLVLQTRLSKIWGQQTDGMKLEFGEENLPKEETEFLSIHSQMTNLEDIDVNHK 1322
Query: 236 SSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEID 275
S ++ KT+L + +QELE + +++++ +Q +
Sbjct: 1323 SKLSSLQDLEKTKLEEQVQELESLISSLQQQLKETEQNYE 1362
Score = 30.8 bits (68), Expect = 1.9
Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 7/82 (8%)
Query: 196 KLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQE 255
+L A ES A K +LA+Y+E+AE+L + EL + ++ +++ + E
Sbjct: 2682 ELEALRAESVAT----KAELASYKEKAEKLQE---ELLVKETNMTSLQKDLSQVRDHLAE 2734
Query: 256 LEETLKLKEEEIERLKQEIDNA 277
+E L + E+E E QE A
Sbjct: 2735 AKEKLSILEKEDETEVQESKKA 2756
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 59.3 bits (142), Expect = 5e-09
Identities = 42/175 (24%), Positives = 83/175 (47%), Gaps = 8/175 (4%)
Query: 184 EAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLH----KRVTELECVSSQA 239
E E+ LK N T E ++ +K + + ++L K+ +EL + ++
Sbjct: 398 EDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKL 457
Query: 240 NAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSL----TQKLQEVE 295
+ ++ Q I+ L+E+L KE+ L+ E+D R E+++S T++LQ++
Sbjct: 458 ETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLT 517
Query: 296 IRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKL 350
L G++ D++ LE + + + ++ L E L K +LT L+D + L
Sbjct: 518 EEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSL 572
Score = 48.1 bits (113), Expect = 1e-05
Identities = 53/197 (26%), Positives = 90/197 (45%), Gaps = 30/197 (15%)
Query: 184 EAELATLKGNNA--KLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECV----SS 237
+ +L TL N+ K +L+ + K+ Q+ A Q E + L R+ E E +
Sbjct: 454 QTKLETLSNQNSDCKQHIEVLKESLTAKE--QRAAILQTEVDALRLRLEEKESFLNKKTK 511
Query: 238 QANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQE---- 293
Q + K L I+++++ L++KE +I L+++I+N +E +D L++
Sbjct: 512 QLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKS 571
Query: 294 --VEIRNKD-----LEGQLSDLEQRLE--KSQNEQ---------EAFRNNLKTLLEILDG 335
+ N D LE LS+ E+ +E K Q E+ E+FR K L E ++
Sbjct: 572 LQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNA 631
Query: 336 KIFELTELRDNLAKLLE 352
ELTE +L L E
Sbjct: 632 LQAELTEKESSLIDLKE 648
Score = 42.4 bits (98), Expect = 6e-04
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 11/172 (6%)
Query: 186 ELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTH 245
E TL G + L + ++++ QE+ K++T L+ + ++ T
Sbjct: 519 EKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLK---DRVKSLQTD 575
Query: 246 KTELNQTIQELEETLKLKEEEIERLKQ--EIDNARELQE------QRDSLTQKLQEVEIR 297
+ + + LEE L KE IERLK+ E D+ L+E + L +K+ ++
Sbjct: 576 SSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAE 635
Query: 298 NKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAK 349
+ E L DL++ + + LK+L ++ K E ++L L K
Sbjct: 636 LTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKK 687
Score = 38.5 bits (88), Expect = 0.009
Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 28/149 (18%)
Query: 212 KQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLK 271
K++ +EEA R+ + Q H L TIQ L++ L+ + + L+
Sbjct: 191 KKERVLRKEEAARM-------SVLKEQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQ 243
Query: 272 QEI--------------DNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQN 317
QE +N R LQ + D ++ +E+ + K LE ++E R+E +
Sbjct: 244 QESGNRGAEHFTIELTEENFRRLQAEHD---RQAKELFLLRKTLE----EMELRIETQKQ 296
Query: 318 EQEAFRNNLKTLLEILDGKIFELTELRDN 346
A ++K LLE+L K L D+
Sbjct: 297 TLNARDESIKKLLEMLQSKGLPSKSLEDD 325
Score = 35.8 bits (81), Expect = 0.060
Identities = 32/159 (20%), Positives = 68/159 (42%), Gaps = 14/159 (8%)
Query: 184 EAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVH 243
E+ L LK + + L +A L+ + +K + + +EE +L ++ + + +
Sbjct: 640 ESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRM-- 697
Query: 244 THKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEG 303
E I++L++ +E + + E+D E+ L+EVE D +
Sbjct: 698 --NPEFADQIKQLDKEASYYRDECGKAQAEVDRLLEI----------LKEVENEKNDKDK 745
Query: 304 QLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTE 342
++++LE + +Q NLK ++ K +L E
Sbjct: 746 KIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQLLE 784
Score = 34.3 bits (77), Expect = 0.17
Identities = 34/162 (20%), Positives = 71/162 (43%), Gaps = 16/162 (9%)
Query: 203 ESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKL 262
++ A V + + L + E K++ ELE ++ + H + N+ + L+ +L
Sbjct: 721 KAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLR------HMKDQNKKVANLKHNQQL 774
Query: 263 KEEEIERLKQEI--------DNARELQ--EQRDSLTQKLQEVEIRNKDLEGQLSDLEQRL 312
++++ +L +E+ DN++ LQ E ++L + QE++ L L ++
Sbjct: 775 EKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKE 834
Query: 313 EKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLECS 354
N + R L+ +LE+ + +D LLE S
Sbjct: 835 AHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELS 876
Score = 33.5 bits (75), Expect = 0.30
Identities = 56/224 (25%), Positives = 91/224 (40%), Gaps = 32/224 (14%)
Query: 100 AEKFQEFKEAARLAKEKSQEKMELTSTPSQES--AGGDLQSPLTPESINGTDDERTPDVT 157
A + KE R++ E++Q ++LT Q+ DL L ES N + T ++T
Sbjct: 201 AARMSVLKEQMRVSHEENQH-LQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELT 259
Query: 158 QNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAA 217
+ + F A EL L+ L E ++ KQ L A
Sbjct: 260 EEN------------FRRLQAEHDRQAKELFLLR-------KTLEEMELRIETQKQTLNA 300
Query: 218 YQEEAERLHKRVTE--LECVSSQANAVHTHK-TELNQTIQELEETLKLKEEEIERLKQEI 274
E ++L + + L S + + T + E + LE L KE+E L++E+
Sbjct: 301 RDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREEL 360
Query: 275 DNARELQEQRDSLTQKLQEVEIRNKD-----LEGQLSDLEQRLE 313
+LQ + + T+ LQ V I KD LE + DLE ++
Sbjct: 361 HRRSQLQPE-PAKTKALQTV-IEMKDTKIASLERNIRDLEDEIQ 402
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 58.9 bits (141), Expect = 7e-09
Identities = 68/287 (23%), Positives = 109/287 (37%), Gaps = 41/287 (14%)
Query: 1 MGEQPIFSTRAHVFQIDPNTKKNWVPT--SKHAVTVSYFYDSTRNVYRIIS--LDGSKAI 56
M EQ I RA V D KK WVP S V ++ + N +R++ + + +
Sbjct: 1 MSEQSICQARAAVMVYDDANKK-WVPAGGSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVV 59
Query: 57 INSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEK 116
IN I + + + +Q F QW D+R VYGL F S+ + FA E
Sbjct: 60 INCAIPKGLKYNQATQTFHQWRDAR--QVYGLNFGSKEDANVFASAMMHALEVLN----- 112
Query: 117 SQEKMELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRAEPTQNALPFSHS 176
SQE+ P P + + P QN P+Q L
Sbjct: 113 -----------SQET------GPTLPR-----QNSQLPAQVQNG-----PSQEELEIQRR 145
Query: 177 SAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVS 236
+ + EL + ++ LE ++ ++ QE+ ER + E +
Sbjct: 146 QLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLE 205
Query: 237 SQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQ 283
Q + E + + + E + + E +ERL++E RE QEQ
Sbjct: 206 RQERLERQERLERQERL-DRERQERQERERLERLERE-RQERERQEQ 250
Score = 28.9 bits (63), Expect = 7.3
Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 18/135 (13%)
Query: 149 DDERTPDVTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANV 208
+ E+ D ++SEP T A S K WE T+ G+ + + +
Sbjct: 466 ETEQKEDKGEDSEP---VTSKASSTSTPEPTRKPWE-RTNTMNGSKSPVISR------RD 515
Query: 209 KQWKQQLAAYQEEAERLHK-RVTELECVSSQANAVHTHKTELNQTIQEL-----EETLKL 262
K Q+ + LH+ + T L S AN V T + ++ Q++ +E KL
Sbjct: 516 SPRKNQIVFDNRSYDSLHRPKSTPLSQPS--ANGVQTEGLDYDRLKQDILDEMRKELTKL 573
Query: 263 KEEEIERLKQEIDNA 277
KEE I+ ++QE+ +
Sbjct: 574 KEELIDAIRQELSKS 588
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 58.9 bits (141), Expect = 7e-09
Identities = 68/287 (23%), Positives = 109/287 (37%), Gaps = 41/287 (14%)
Query: 1 MGEQPIFSTRAHVFQIDPNTKKNWVPT--SKHAVTVSYFYDSTRNVYRIIS--LDGSKAI 56
M EQ I RA V D KK WVP S V ++ + N +R++ + + +
Sbjct: 1 MSEQSICQARAAVMVYDDANKK-WVPAGGSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVV 59
Query: 57 INSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEK 116
IN I + + + +Q F QW D+R VYGL F S+ + FA E
Sbjct: 60 INCAIPKGLKYNQATQTFHQWRDAR--QVYGLNFGSKEDANVFASAMMHALEVLN----- 112
Query: 117 SQEKMELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRAEPTQNALPFSHS 176
SQE+ P P + + P QN P+Q L
Sbjct: 113 -----------SQET------GPTLPR-----QNSQLPAQVQNG-----PSQEELEIQRR 145
Query: 177 SAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVS 236
+ + EL + ++ LE ++ ++ QE+ ER + E +
Sbjct: 146 QLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLE 205
Query: 237 SQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQ 283
Q + E + + + E + + E +ERL++E RE QEQ
Sbjct: 206 RQERLERQERLERQERL-DRERQERQERERLERLERE-RQERERQEQ 250
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 58.9 bits (141), Expect = 7e-09
Identities = 68/261 (26%), Positives = 113/261 (43%), Gaps = 26/261 (9%)
Query: 79 DSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKMELTS-TPSQESAGGDLQ 137
D V L E +S+F E L +EK+ E M+L + E ++
Sbjct: 2017 DDLQKQVKALEIDVEEQVSRFIE----------LEQEKNTELMDLRQQNQALEKQLEKMR 2066
Query: 138 SPLTPESINGTDDERTPDVTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKL 197
L ++I D E DV Q + E +P IS+H E+ L + +
Sbjct: 2067 KFLDEQAI---DREHERDVFQQEIQKLEQQLKVVP--RFQPISEHQTREVEQLANHLKEK 2121
Query: 198 TAALLESTANVKQWKQQLAAYQEEAERLHKRVTELE---CVSSQA-----NAVHTHKTEL 249
T E + +Q ++ + EE E+L RV ELE VS+ + H E
Sbjct: 2122 TDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEA 2181
Query: 250 NQTIQELEETLKLKEEEIERLKQEIDNARELQEQ-RDSLTQKLQEVEIRNKDLEGQLSDL 308
+ LE L+ + + I+R ++EI N E EQ R+ L K +EV+ + LE Q +
Sbjct: 2182 KPELS-LEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKES 2240
Query: 309 EQRLEKSQNEQEAFRNNLKTL 329
RL++ + E + F+++++ L
Sbjct: 2241 TTRLQELEQENKLFKDDMEKL 2261
Score = 50.8 bits (120), Expect = 2e-06
Identities = 39/146 (26%), Positives = 72/146 (49%), Gaps = 1/146 (0%)
Query: 207 NVKQWKQQLAAYQEEAERLHKRVTEL-ECVSSQANAVHTHKTELNQTIQELEETLKLKEE 265
N++Q + Q+ Q E + R TEL E +SS+ V K+EL QT ELE TLK + +
Sbjct: 3125 NIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHK 3184
Query: 266 EIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNN 325
++ L+ ++ ++ L L + ++++L+ L + +L +S+ + +
Sbjct: 3185 HLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELED 3244
Query: 326 LKTLLEILDGKIFELTELRDNLAKLL 351
LK LE + +L L + +LL
Sbjct: 3245 LKFSLESQKQRNLQLNLLLEQQKQLL 3270
Score = 49.7 bits (117), Expect = 4e-06
Identities = 44/192 (22%), Positives = 99/192 (51%), Gaps = 28/192 (14%)
Query: 156 VTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQL 215
+ ++ E E + L FSH E EL+ LK + +E N+++ K L
Sbjct: 614 MAESQEAELERLRTQLLFSH--------EEELSKLKEDLE------IEHRINIEKLKDNL 659
Query: 216 AA-YQEEAERLHKRVTE-LECVSSQANAVHTHKTELNQTIQELEET----LKLKEEE--- 266
Y+++ + L +++ +E + + + + T + +L I +L++ + K EE
Sbjct: 660 GIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTL 719
Query: 267 -IERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQL----SDLEQRLEKSQNEQEA 321
I L++EI+ R+ ++++ +L Q++QE++++ + LE Q+ +DL+++ + + E
Sbjct: 720 QINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSI 779
Query: 322 FRNNLKTLLEIL 333
++ KTL ++L
Sbjct: 780 LKDEKKTLEDML 791
Score = 45.1 bits (105), Expect = 1e-04
Identities = 69/320 (21%), Positives = 127/320 (39%), Gaps = 39/320 (12%)
Query: 39 DSTRNVYRIISLDGSKAI-INSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLS 97
D V R I L+ K + N K +K ++ D +A EH
Sbjct: 2029 DVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQA-------IDREHERD 2081
Query: 98 KFAEKFQEFKEAARLA------KEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDE 151
F ++ Q+ ++ ++ E ++E + +E + L+ E + E
Sbjct: 2082 VFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQE 2141
Query: 152 RTPDVTQNSEPRAEPTQNALPFSHSSAIS----KHWEAELA----TLKGNNAKLTAALLE 203
R ++ + E R + AL S + KH+ A A +L+ A+
Sbjct: 2142 RNEEI-EKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDAIDR 2200
Query: 204 STANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLK 263
+ ++QL ++EE E ++ V +L + K E +QELE+ KL
Sbjct: 2201 KEKEITNLEEQLEQFREELENKNEEVQQLHM------QLEIQKKESTTRLQELEQENKLF 2254
Query: 264 EEEIERLKQEI--DNARELQEQR---DSLTQKLQEVEIRNKDLEGQLSDLEQRLE----- 313
++++E+L I +A Q+Q Q +QE E+ L Q++ L+Q+L+
Sbjct: 2255 KDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDN 2314
Query: 314 KSQNEQEAFRNNLKTLLEIL 333
K E+ +L+T +E L
Sbjct: 2315 KVIEEKNELIRDLETQIECL 2334
Score = 42.4 bits (98), Expect = 6e-04
Identities = 37/147 (25%), Positives = 77/147 (52%), Gaps = 17/147 (11%)
Query: 203 ESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKL 262
EST +++ +Q+ ++++ E+L + E + +S+Q H + Q IQE
Sbjct: 2239 ESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQ--HVLFGKFAQIIQE------- 2289
Query: 263 KEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAF 322
KE EI++L +++ +LQ+Q +T + +E +N+ + DLE ++E ++QE
Sbjct: 2290 KEVEIDQLNEQV---TKLQQQL-KITTDNKVIEEKNE----LIRDLETQIECLMSDQECV 2341
Query: 323 RNNLKTLLEILDGKIFELTELRDNLAK 349
+ N + +E L+ I +L + N+ +
Sbjct: 2342 KRNREEEIEQLNEVIEKLQQELANIGQ 2368
Score = 38.5 bits (88), Expect = 0.009
Identities = 41/192 (21%), Positives = 83/192 (43%), Gaps = 22/192 (11%)
Query: 165 EPTQNALPFSHSSAISKHWEAELATLKGNNAKL-------TAALLESTANVKQWKQQLAA 217
+P L + SS + E L + +++L T + ES ++ + L
Sbjct: 1836 DPENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKC 1895
Query: 218 YQEEAERLHKR-------VTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEI--- 267
+E ERLH+ EL + KT + IQE + + E+E+
Sbjct: 1896 QEELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCA 1955
Query: 268 -ERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKS----QNEQEAF 322
RL++ +++QE+R+ L+++ + ++ +E QL ++L K Q + E
Sbjct: 1956 SNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKV 2015
Query: 323 RNNLKTLLEILD 334
R++L+ ++ L+
Sbjct: 2016 RDDLQKQVKALE 2027
Score = 38.1 bits (87), Expect = 0.012
Identities = 33/144 (22%), Positives = 61/144 (42%), Gaps = 7/144 (4%)
Query: 191 KGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELN 250
KG + T N Q K A E +L ++ E + + + K L
Sbjct: 468 KGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQ 527
Query: 251 QTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQ 310
+ +++L E L E+I+R +Q I E + + + + L VE DL+ ++ +
Sbjct: 528 RQLEDLVEELSFSREQIQRARQTI---AEQESKLNEAHKSLSTVE----DLKAEIVSASE 580
Query: 311 RLEKSQNEQEAFRNNLKTLLEILD 334
++ + + EA N K LE+L+
Sbjct: 581 SRKELELKHEAEVTNYKIKLEMLE 604
Score = 37.4 bits (85), Expect = 0.021
Identities = 33/148 (22%), Positives = 76/148 (51%), Gaps = 13/148 (8%)
Query: 212 KQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLK 271
K+++ + E L+ ++ E E + + T ++ + EL+E + K +EI+ +K
Sbjct: 321 KEEIQEKETIIEELNTKIIEEE---KKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMK 377
Query: 272 QEIDNARELQEQRDSLTQKL----QEVEIRNKDLEGQLSDLEQRLE-KSQNEQEAFRNNL 326
E+ N+++ + Q ++L +E++ RN +D+ QR+E ++Q + E R L
Sbjct: 378 LELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAEL 437
Query: 327 KTLLEILDGKIFELTE--LRDNLAKLLE 352
E+ +I ++ + +R ++A++ E
Sbjct: 438 D---EMYGQQIVQMKQELIRQHMAQMEE 462
Score = 37.0 bits (84), Expect = 0.027
Identities = 58/253 (22%), Positives = 108/253 (42%), Gaps = 38/253 (15%)
Query: 107 KEAARLAKEKSQEKMELT----STPSQESAGGDL------QSPLTPESINGTDDERTPDV 156
KE A+L + + ++K EL S SQ+ L Q L ES + +R
Sbjct: 3226 KEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYD 3285
Query: 157 TQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQ---WKQ 213
Q SE + + + + + L + +A+L ++ + T + +
Sbjct: 3286 AQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSS--DGTGQSRPPLPSED 3343
Query: 214 QLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEE-------TLKLKEE- 265
L Q++ E H R+ EL N +K + QT Q++E+ TL+ ++E
Sbjct: 3344 LLKELQKQLEEKHSRIVEL------LNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEA 3397
Query: 266 --EIERLKQEIDN-ARELQEQRDSLTQKLQEVEIRNKDLEGQ-LSDLEQRLEKSQNEQEA 321
E ++ E+ + +LQ Q + Q++ ++ DLEGQ L + Q +K + E+E
Sbjct: 3398 NTEGQKKMHELQSKVEDLQRQLEEKRQQVYKL-----DLEGQRLQGIMQEFQKQELEREE 3452
Query: 322 FRNNLKTLLEILD 334
R + + L + L+
Sbjct: 3453 KRESRRILYQNLN 3465
Score = 36.2 bits (82), Expect = 0.046
Identities = 40/191 (20%), Positives = 83/191 (43%), Gaps = 35/191 (18%)
Query: 181 KHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQAN 240
+ +EA + G +LTA L ++ + ++ E++++L + +L+ + N
Sbjct: 194 QEFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQLQASETLRN 253
Query: 241 AVH---------------THKTELNQTIQELEETLKLKEE---------------EIERL 270
+ H TH+ +L + LE+ K KE+ E+E+
Sbjct: 254 STHSSTAADLLQAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQD 313
Query: 271 KQ-EIDNARELQEQR---DSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNL 326
K+ E N E+QE+ + L K+ E E + +L+ +L+ ++ L + Q + +
Sbjct: 314 KKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEI 373
Query: 327 KTL-LEILDGK 336
K + LE+ + K
Sbjct: 374 KNMKLELTNSK 384
Score = 35.8 bits (81), Expect = 0.060
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 13/91 (14%)
Query: 212 KQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLK 271
K +A E E + K TEL + K EL+Q + +L E LK K EI L
Sbjct: 921 KTFVAETLEMGEVVEKDTTEL---MEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLN 977
Query: 272 QEIDNARELQEQRDSLTQKLQEVEIRNKDLE 302
+E+ SL Q+ ++V +R ++LE
Sbjct: 978 EEVK----------SLKQEKEQVSLRCRELE 998
Score = 35.4 bits (80), Expect = 0.078
Identities = 26/123 (21%), Positives = 60/123 (48%), Gaps = 10/123 (8%)
Query: 208 VKQWKQQLAAYQEEAERLHKRVTE----LECVSSQANAVHTHKTELNQTIQELEETLKLK 263
++ ++ ++ +QE L +VTE L + ++ + + +T+ ++ EE L +
Sbjct: 1242 LQDYRYEVQDFQENMHTLLNKVTEEYNKLLVLQTRLSKIWGQQTD-GMKLEFGEENLPKE 1300
Query: 264 EEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRN-----KDLEGQLSDLEQRLEKSQNE 318
E E + ++ N ++ S LQ++E ++LE +S L+Q+L++++
Sbjct: 1301 ETEFLSIHSQMTNLEDIDVNHKSKLSSLQDLEKTKLEEQVQELESLISSLQQQLKETEQN 1360
Query: 319 QEA 321
EA
Sbjct: 1361 YEA 1363
Score = 34.7 bits (78), Expect = 0.13
Identities = 34/137 (24%), Positives = 64/137 (46%), Gaps = 19/137 (13%)
Query: 213 QQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQ 272
Q+L A Q++ + E E +S Q A+ + Q Q L+ET KL +E++E Q
Sbjct: 1960 QELEAEQQQIQE------ERELLSRQKEAMKAEAGPVEQ--QLLQETEKLMKEKLEVQCQ 2011
Query: 273 EIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQ----RLEKSQNEQEAFRNNLKT 328
++ RD L ++++ +EI ++ + +LEQ L + + +A L+
Sbjct: 2012 A-------EKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEK 2064
Query: 329 LLEILDGKIFELTELRD 345
+ + LD + + RD
Sbjct: 2065 MRKFLDEQAIDREHERD 2081
Score = 34.3 bits (77), Expect = 0.17
Identities = 60/254 (23%), Positives = 105/254 (41%), Gaps = 31/254 (12%)
Query: 104 QEFKEAARLAKE--KSQEKMELTSTPSQESAGGDLQ---SPLTPESINGTDDERT-PDVT 157
QE KE L +E + Q K EL +E DLQ + L E+ D+++T D+
Sbjct: 733 QEEKEKGTLEQEVQELQLKTELLEKQMKEKEN-DLQEKFAQLEAENSILKDEKKTLEDML 791
Query: 158 QNSEPRAEPTQNA-LPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANV-------- 208
+ P ++ + L S + WE E+ L N L ++ +
Sbjct: 792 KIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFS 851
Query: 209 ---KQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELE------ET 259
K ++ QEE L K +LE S+ +K++L +EL T
Sbjct: 852 FAEKNFEVNYQELQEEYACLLKVKDDLE--DSKNKQELEYKSKLKALNEELHLQRINPTT 909
Query: 260 LKLKEEEIERLKQEIDNARELQE--QRDS--LTQKLQEVEIRNKDLEGQLSDLEQRLEKS 315
+K+K + K + E+ E ++D+ L +KL+ + +L +LSDL ++L++
Sbjct: 910 VKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQK 969
Query: 316 QNEQEAFRNNLKTL 329
E +K+L
Sbjct: 970 HGEISFLNEEVKSL 983
Score = 33.9 bits (76), Expect = 0.23
Identities = 28/131 (21%), Positives = 57/131 (43%), Gaps = 1/131 (0%)
Query: 219 QEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNAR 278
QE +L + EL+ + Q V + + Q + ++EE + E+E + N
Sbjct: 424 QETQRKLEQLRAELDEMYGQ-QIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNIT 482
Query: 279 ELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIF 338
++Q + + E+ I+ +D Q L++ L E+ A + L+ L+E L
Sbjct: 483 VNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSRE 542
Query: 339 ELTELRDNLAK 349
++ R +A+
Sbjct: 543 QIQRARQTIAE 553
Score = 32.7 bits (73), Expect = 0.51
Identities = 25/81 (30%), Positives = 45/81 (55%), Gaps = 7/81 (8%)
Query: 248 ELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSD 307
E++ + + L L EE++E ++QE+ R+ QE + + T+ L++ +R +E Q D
Sbjct: 1568 EISVSSMDASRQLMLNEEQLEDMRQEL--VRQYQEHQQA-TELLRQAHMR--QMERQRED 1622
Query: 308 LEQRLE--KSQNEQEAFRNNL 326
EQ E K N Q A R+++
Sbjct: 1623 QEQLQEEIKRLNRQLAQRSSI 1643
Score = 32.3 bits (72), Expect = 0.66
Identities = 26/125 (20%), Positives = 54/125 (43%), Gaps = 5/125 (4%)
Query: 191 KGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELN 250
K + + + L+ V + +Q E + ++ T +E ++++ EL
Sbjct: 290 KKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELK 349
Query: 251 QTIQELEETLKLKEEEIERLKQEIDNAR-ELQEQRDSLTQKLQEVEIRNKDLEGQLSDLE 309
+ ++ L +E+I + QEI N + EL + Q +E+ K L G + +L+
Sbjct: 350 DKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEI----KQLMGTVEELQ 405
Query: 310 QRLEK 314
+R K
Sbjct: 406 KRNHK 410
Score = 32.3 bits (72), Expect = 0.66
Identities = 41/169 (24%), Positives = 79/169 (46%), Gaps = 8/169 (4%)
Query: 184 EAELATLKGNNAKLTAALLESTANVK-QWKQQLAAYQEEAERLHKRVTELECVSSQANA- 241
++E TL+ N + +L K +Q++ Q + E L K++ E E + A
Sbjct: 713 KSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQ 772
Query: 242 VHTHKTELNQTIQELEETLKLKE--EEIERLKQEIDNARELQEQRDSLTQKLQEVEIR-N 298
+ + L + LE+ LK+ + ERL +D+ + + +DS+ +K E+ I N
Sbjct: 773 LEAENSILKDEKKTLEDMLKIHTPVSQEERLIF-LDSIKS--KSKDSVWEKEIEILIEEN 829
Query: 299 KDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNL 347
+DL+ Q L + +EK +N N + + L + L +++D+L
Sbjct: 830 EDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDL 878
Score = 32.3 bits (72), Expect = 0.66
Identities = 27/117 (23%), Positives = 59/117 (50%), Gaps = 6/117 (5%)
Query: 219 QEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNAR 278
QEE +RL++++ + + ++ N V + L ++ELE +L E+L E+ N+
Sbjct: 1627 QEEIKRLNRQLAQRSSIDNE-NLVSERERVL---LEELEALKQLSLAGREKLCCELRNSS 1682
Query: 279 ELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNE--QEAFRNNLKTLLEIL 333
+ + +++E + K+L+ + D+ + ++ Q+A LK LLE++
Sbjct: 1683 TQTQNGNENQGEVEEQTFKEKELDRKPEDVPPEILSNERYALQKANNRLLKILLEVV 1739
Score = 32.3 bits (72), Expect = 0.66
Identities = 21/88 (23%), Positives = 43/88 (48%), Gaps = 3/88 (3%)
Query: 231 ELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARE-LQEQRD--SL 287
ELE + +++ A + ++L+E L +KE + L++++ R+ L E ++ S+
Sbjct: 2690 ELEALRAESVATKAELASYKEKAEKLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLSI 2749
Query: 288 TQKLQEVEIRNKDLEGQLSDLEQRLEKS 315
+K E E++ L +L KS
Sbjct: 2750 LEKEDETEVQESKKACMFEPLPIKLSKS 2777
Score = 32.0 bits (71), Expect = 0.86
Identities = 30/121 (24%), Positives = 60/121 (49%), Gaps = 12/121 (9%)
Query: 202 LESTANVKQ--WKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEET 259
LE + N ++ +K +L A EE LH + V +++ KT + +T++ E
Sbjct: 878 LEDSKNKQELEYKSKLKALNEE---LHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVV 934
Query: 260 LKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQ 319
K E +E+L E+ +L+ L+Q+L ++ + K G++S L + ++ + E+
Sbjct: 935 EKDTTELMEKL--EVTKREKLE-----LSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEK 987
Query: 320 E 320
E
Sbjct: 988 E 988
Score = 31.2 bits (69), Expect = 1.5
Identities = 36/183 (19%), Positives = 77/183 (42%), Gaps = 23/183 (12%)
Query: 186 ELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTH 245
E L+ L L S +++ +Q +A + + HK ++ +E + ++ +
Sbjct: 522 EKCALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASES 581
Query: 246 KTELNQTIQELEETLKLKEEEIERLKQEI-DNARELQE-------------QRDSLTQKL 291
+ EL + K+K E +E+ K + D E QE + L++
Sbjct: 582 RKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLK 641
Query: 292 QEVEIRNKDLEGQLSD-----LEQRLEKSQNEQ----EAFRNNLKTLLEILDGKIFELTE 342
+++EI ++ +L D +Q+++ QNE E + L+ + I E+++
Sbjct: 642 EDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISK 701
Query: 343 LRD 345
L+D
Sbjct: 702 LKD 704
Score = 31.2 bits (69), Expect = 1.5
Identities = 33/160 (20%), Positives = 63/160 (39%), Gaps = 26/160 (16%)
Query: 134 GDLQSPLTPESINGTDDERTPD-VTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKG 192
G+ +P +N D E + D +++N +P + + + E L
Sbjct: 1211 GEYYTPALKCEVNAEDKENSGDYISENEDPELQ--------DYRYEVQDFQENMHTLLNK 1262
Query: 193 NNAKLTAALLESTANVKQWKQQLAAYQ----------EEAERL--HKRVTELECV----- 235
+ L+ T K W QQ + EE E L H ++T LE +
Sbjct: 1263 VTEEYNKLLVLQTRLSKIWGQQTDGMKLEFGEENLPKEETEFLSIHSQMTNLEDIDVNHK 1322
Query: 236 SSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEID 275
S ++ KT+L + +QELE + +++++ +Q +
Sbjct: 1323 SKLSSLQDLEKTKLEEQVQELESLISSLQQQLKETEQNYE 1362
Score = 30.8 bits (68), Expect = 1.9
Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 7/82 (8%)
Query: 196 KLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQE 255
+L A ES A K +LA+Y+E+AE+L + EL + ++ +++ + E
Sbjct: 2690 ELEALRAESVAT----KAELASYKEKAEKLQE---ELLVKETNMTSLQKDLSQVRDHLAE 2742
Query: 256 LEETLKLKEEEIERLKQEIDNA 277
+E L + E+E E QE A
Sbjct: 2743 AKEKLSILEKEDETEVQESKKA 2764
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 58.5 bits (140), Expect = 9e-09
Identities = 65/267 (24%), Positives = 121/267 (45%), Gaps = 20/267 (7%)
Query: 93 EHHLSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDER 152
E + K + + +K+ KEK + + +E+ L+ L +++ T D +
Sbjct: 1042 EQQIEKLQAEVKGYKDENNRLKEKEHKNQD-DLLKEKETLIQQLKEELQEKNV--TLDVQ 1098
Query: 153 TPDVTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLK---GNNAKLTAALLESTANVK 209
V + +E TQ + A K E L T K ++AKL +LE + +
Sbjct: 1099 IQHVVEGKRALSELTQGVTCYK---AKIKELETILETQKVECSHSAKLEQDILEKESIIL 1155
Query: 210 QWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIER 269
+ ++ L +QE + K +L + + T+L +Q+++ L+LKEEE E
Sbjct: 1156 KLERNLKEFQEHLQDSVKNTKDLNVKELK---LKEEITQLTNNLQDMKHLLQLKEEEEET 1212
Query: 270 LKQEIDNARELQEQRDSLTQK----LQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNN 325
+QE + +E + TQ LQ E DL+ +L+D ++++++ Q E R+
Sbjct: 1213 NRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDE 1272
Query: 326 LKTLLEILDGKIFELTELRDNLAKLLE 352
K LL I KI EL + ++ ++ L+
Sbjct: 1273 DK-LLRI---KINELEKKKNQCSQELD 1295
Score = 50.8 bits (120), Expect = 2e-06
Identities = 52/194 (26%), Positives = 97/194 (50%), Gaps = 30/194 (15%)
Query: 174 SHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELE 233
S SSA +++ +A+L + + A L L ++ +KQ +++++ ++E + L ++ ELE
Sbjct: 1225 SASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELE 1284
Query: 234 CVSSQAN--------AVHTHKTELN-----QTIQELE---ETLKLKEEEIERLKQEIDNA 277
+Q + + K +LN + IQ+ E + L +KE+ IE ++ ++
Sbjct: 1285 KKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQ 1344
Query: 278 RELQEQRDS-LTQKLQEVEIRNKDLE---GQLSDLEQRLEKSQNEQEAFRNNLKTLLEIL 333
+ Q ++D L KL+EVE +LE + +DLE + + N++ NN L
Sbjct: 1345 EQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEH--ENNTDVL---- 1398
Query: 334 DGKIFELTELRDNL 347
GK LT L+D L
Sbjct: 1399 -GK---LTNLQDEL 1408
Score = 37.4 bits (85), Expect = 0.021
Identities = 56/284 (19%), Positives = 116/284 (40%), Gaps = 27/284 (9%)
Query: 69 KTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAAR--LAKEKSQEKMELTST 126
K + Q D + T+ L + + K E Q+++ A + KEK E M +T
Sbjct: 1285 KKKNQCSQELDMKQRTIQQL--KEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLE 1342
Query: 127 PSQESAGGD---LQSPLTPESINGTDDERTPDVTQNSEPRAEPTQNALPFSHSSAISK-- 181
+++ L++ L T+ E+ + + E + N +++ + K
Sbjct: 1343 EQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLT 1402
Query: 182 HWEAELATLKGN-NAKLTAALLESTANVKQWKQ-------QLAAYQEEAERLHKRVTELE 233
+ + EL + NA L E + Q K+ ++ Y E+ ER K+ E+E
Sbjct: 1403 NLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEME 1462
Query: 234 CVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQE 293
+++Q TE + +Q+ E +++ + L+ ++ Q+D+ ++L+
Sbjct: 1463 ILTAQL-------TEKDSDLQKWREE---RDQLVAALEIQLKALISSNVQKDNEIEQLKR 1512
Query: 294 VEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKI 337
+ +E Q+ D++ + S + + L T EI KI
Sbjct: 1513 IISETSKIETQIMDIKPKRISSADPDKLQTEPLSTSFEISRNKI 1556
Score = 32.3 bits (72), Expect = 0.66
Identities = 27/161 (16%), Positives = 69/161 (42%), Gaps = 15/161 (9%)
Query: 185 AELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHT 244
AEL K N + +++ + ++ + + + + +H ++ EL + S + +
Sbjct: 905 AELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLDSVSQISNI 964
Query: 245 HKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQR--------------DSLTQK 290
L EE L +++ L + +++++E R +++ ++
Sbjct: 965 DLLNLRDLSNGSEED-NLPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIWEE 1023
Query: 291 LQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLE 331
+E+ + Q+ +LEQ++EK Q E + +++ L E
Sbjct: 1024 CKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKE 1064
Score = 32.3 bits (72), Expect = 0.66
Identities = 38/159 (23%), Positives = 68/159 (42%), Gaps = 27/159 (16%)
Query: 213 QQLAAYQEEAERL-------HKRVTELECVSSQ-ANAVHTHKTELNQTIQELEETLKLKE 264
Q L A EE ERL ++ +LE ++Q +N H + T++ + L++ L+ E
Sbjct: 1353 QVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESE 1412
Query: 265 EE--------IERLKQEIDNARELQ-----------EQRDSLTQKLQEVEIRNKDLEGQL 305
++ +E I A+E + E R+ ++ E+EI L +
Sbjct: 1413 QKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKD 1472
Query: 306 SDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELR 344
SDL++ E+ A LK L+ K E+ +L+
Sbjct: 1473 SDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLK 1511
Score = 30.8 bits (68), Expect = 1.9
Identities = 28/135 (20%), Positives = 70/135 (51%), Gaps = 13/135 (9%)
Query: 213 QQLAAYQ-EEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIE--- 268
+Q+ Y+ +E R + + +E + + + ++ + I+ELE+ ++ + E++
Sbjct: 997 KQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYK 1056
Query: 269 ----RLKQ-EIDNARELQEQRDSLTQKL-QEVEIRNKDLEGQLSDL---EQRLEKSQNEQ 319
RLK+ E N +L +++++L Q+L +E++ +N L+ Q+ + ++ L +
Sbjct: 1057 DENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGV 1116
Query: 320 EAFRNNLKTLLEILD 334
++ +K L IL+
Sbjct: 1117 TCYKAKIKELETILE 1131
Score = 30.0 bits (66), Expect = 3.3
Identities = 44/204 (21%), Positives = 83/204 (40%), Gaps = 24/204 (11%)
Query: 137 QSPLTPESINGTDDERTPDVTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAK 196
Q P+++N + ++ V + + + N+ + A WE L L +
Sbjct: 477 QKVCVPDTLNSSQEKLFGPVKSSQDVSLDSNSNSKILNVKRATIS-WENSLEDLMEDED- 534
Query: 197 LTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQEL 256
L+E N ++ + +E L K + E ++A H K +L I++L
Sbjct: 535 ----LVEELENAEETQNVETKLLDED--LDKTLEE-----NKAFISHEEKRKLLDLIEDL 583
Query: 257 EETLKLKEEEIERLKQEIDNAREL---------QEQRDSLTQKLQEVEIRNKDLEGQLSD 307
++ KL E+ E+L E E+ Q + D LQE EI ++ E +L+
Sbjct: 584 KK--KLINEKKEKLTLEFKIREEVTQEFTQYWAQREADFKETLLQEREILEENAERRLAI 641
Query: 308 LEQRLEKSQNEQEAFRNNLKTLLE 331
+ + K +EA ++ T +E
Sbjct: 642 FKDLVGKCDTREEAAKDICATKVE 665
Score = 29.6 bits (65), Expect = 4.3
Identities = 25/110 (22%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 237 SQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNAR-ELQEQRDSLTQKLQEVE 295
++ N+ H+ + + +E+ + K +IE L+Q+I+ + E++ +D +L+E E
Sbjct: 1008 NRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDE-NNRLKEKE 1066
Query: 296 IRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLE-ILDGK--IFELTE 342
+N+D L + E +++ + E + L ++ +++GK + ELT+
Sbjct: 1067 HKNQD--DLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQ 1114
>gi|50083293 coiled-coil domain containing 123 [Homo sapiens]
Length = 783
Score = 56.6 bits (135), Expect = 3e-08
Identities = 49/171 (28%), Positives = 81/171 (47%), Gaps = 17/171 (9%)
Query: 195 AKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQ 254
+KLT L+ A +++LA +E+ E L + EL+ S AV HK+ +N+
Sbjct: 463 SKLTKQLMLLEAKTHGQEKELAENREQLEILRAKCQELKTHSDGKIAVEVHKSIVNELKS 522
Query: 255 ELEETLKLKEEEIERLKQE--IDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRL 312
+L+ KEEE ER + E ++ LQ Q+ SL + + +NK LE +L ++
Sbjct: 523 QLQ-----KEEEKERAEMEELMEKLTVLQAQKKSLLLEKNSLTEQNKALEAELERAQKIN 577
Query: 313 EKSQNEQEAFRNNLK----------TLLEILDGKIFELTELRDNLAKLLEC 353
KSQ + E + ++ L L G +T+ RD+L L +C
Sbjct: 578 RKSQKKIEVLKKQVEKAMGNEMSAHQYLANLVGLAENITQERDSLMCLAKC 628
Score = 29.6 bits (65), Expect = 4.3
Identities = 36/144 (25%), Positives = 67/144 (46%), Gaps = 10/144 (6%)
Query: 194 NAKLTAALLESTA-NVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQT 252
N +L L +S+A ++W+Q + E + +LE Q A +H+ L Q
Sbjct: 405 NEELHQELNKSSAVTSEEWRQLQTQAKLVLEENKLLLEQLEI--QQRKAKDSHQERL-QE 461
Query: 253 IQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKD---LEGQLSDLE 309
+ +L + L L E + ++E+ E +EQ + L K QE++ + +E S +
Sbjct: 462 VSKLTKQLMLLEAKTHGQEKEL---AENREQLEILRAKCQELKTHSDGKIAVEVHKSIVN 518
Query: 310 QRLEKSQNEQEAFRNNLKTLLEIL 333
+ + Q E+E R ++ L+E L
Sbjct: 519 ELKSQLQKEEEKERAEMEELMEKL 542
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 56.2 bits (134), Expect = 4e-08
Identities = 53/254 (20%), Positives = 113/254 (44%), Gaps = 24/254 (9%)
Query: 92 SEHHLSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDE 151
+E L K++E ++ +E LA++K+ + E A + + L E ++ +
Sbjct: 54 TEDELDKYSEALKDAQEKLELAEKKAADA-------EAEVASLNRRIQLVEEELDRAQER 106
Query: 152 RTPDVT--QNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVK 209
+ + +E A+ ++ + + A+ + EL ++ AK A
Sbjct: 107 LATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIA---------- 156
Query: 210 QWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIER 269
++ Y+E A +L +LE +A + +EL + ++ + LK E + E+
Sbjct: 157 --EEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEK 214
Query: 270 LKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTL 329
Q+ D + +E+ LT KL+E E R + E ++ LE+ ++ ++E A + K +
Sbjct: 215 YSQKED---KYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAI 271
Query: 330 LEILDGKIFELTEL 343
E LD + ++T +
Sbjct: 272 SEELDHALNDMTSI 285
Score = 36.2 bits (82), Expect = 0.046
Identities = 25/123 (20%), Positives = 57/123 (46%), Gaps = 13/123 (10%)
Query: 212 KQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLK 271
K+++ + + E R + E QA +L + +++ LK E+E+++
Sbjct: 6 KKKMQMLKLDKENALDRAEQAEAEQKQAEE---RSKQLEDELAAMQKKLKGTEDELDKYS 62
Query: 272 QEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLE 331
+ + +A+E KL+ E + D E +++ L +R++ + E + + L T L+
Sbjct: 63 EALKDAQE----------KLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQ 112
Query: 332 ILD 334
L+
Sbjct: 113 KLE 115
Score = 35.0 bits (79), Expect = 0.10
Identities = 35/156 (22%), Positives = 71/156 (45%), Gaps = 20/156 (12%)
Query: 209 KQWKQQLAAYQEE-----------AERLHKRVTELECVSSQANAVHTHKTELNQTIQELE 257
KQ + +LAA Q++ +E L +LE +A LN+ IQ +E
Sbjct: 38 KQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVE 97
Query: 258 ETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKD----LEGQLSDLEQRLE 313
E L +E + Q+++ A + ++ + + ++ +++++ E QL + + E
Sbjct: 98 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 157
Query: 314 KSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAK 349
++ + E + L I++G + E TE R LA+
Sbjct: 158 EADRKYE----EVARKLVIIEGDL-ERTEERAELAE 188
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 55.5 bits (132), Expect = 7e-08
Identities = 69/290 (23%), Positives = 123/290 (42%), Gaps = 38/290 (13%)
Query: 96 LSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQESAGG-----------------DLQS 138
L + E Q+ K+ A L E +E ME+ T ESAG +LQ
Sbjct: 462 LKEQCENLQQEKQEAILNYESLREIMEILQTELGESAGKISQEFESMKQQQASDVHELQQ 521
Query: 139 PLTP---------ESINGTDDERTPDVTQNS-EPRAEPTQNALPFSHSSAISKHWEAE-- 186
L E++N E ++Q P E T L + + + +
Sbjct: 522 KLRTAFTEKDALLETVNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYLLSLSQRDTM 581
Query: 187 LATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHK 246
L L+G LT + +K +++ + ++ ER + + EL + +
Sbjct: 582 LKELEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCEREERLILEL---GKKVEQTIQYN 638
Query: 247 TELNQTIQEL----EETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLE 302
+EL Q + EL EETLK K++ ++L++ + + L E ++ L+ +++ + N L
Sbjct: 639 SELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLS 698
Query: 303 GQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLE 352
+ L + LE +++E LK + L+ K+ + E +DNL KLLE
Sbjct: 699 SEKKQLSRDLEVFLSQKEDV--ILKEHITQLEKKLQLMVEEQDNLNKLLE 746
Score = 47.4 bits (111), Expect = 2e-05
Identities = 64/274 (23%), Positives = 120/274 (43%), Gaps = 31/274 (11%)
Query: 96 LSKFAEK-FQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDERTP 154
L KFA+K ++A E +E EL S P E G D+ LT ER
Sbjct: 30 LIKFAKKQMMLIQKAKSRCTELEKEIEELRSKPVTEGTG-DIIKALT---------ERLD 79
Query: 155 DVTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAK-LTAALLESTANVKQWKQ 213
+ +AE Q L + K + T G+ K L + + ++ K
Sbjct: 80 ALLLE---KAETEQQCLSLKKENIKMKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKN 136
Query: 214 QLAA----YQEEAERLHKRV-----TELECVSSQANAVHTHKTELNQTIQELEETLKLKE 264
+L A Y E+ L K++ T+LE +S Q + + + + +E+E+ E
Sbjct: 137 ELMAVRSKYSEDKANLQKQLEEAMNTQLE-LSEQLKFQNNSEDNVKKLQEEIEKIRPGFE 195
Query: 265 EEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEK----SQNEQE 320
E+I L++++D + E+++++TQ +E ++ + ++ L++ L + Q E +
Sbjct: 196 EQILYLQKQLDATTD--EKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVK 253
Query: 321 AFRNNLKTLLEILDGKIFELTELRDNLAKLLECS 354
++ + + +I +L EL++NL K E S
Sbjct: 254 ELMCQIEASAKEHEAEINKLNELKENLVKQCEAS 287
Score = 45.1 bits (105), Expect = 1e-04
Identities = 35/176 (19%), Positives = 89/176 (50%), Gaps = 9/176 (5%)
Query: 185 AELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHT 244
AEL LK + AK + + ++VK+ ++++ ++E + +++ +++ V+ +A
Sbjct: 923 AELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELD 982
Query: 245 HKTELNQTIQELEETLKLKEEEIER----LKQEIDNARELQEQRDSLTQKLQEVEIRNKD 300
+ QT++E E+L+ +++++ L Q ++ + L + + +++L + R +
Sbjct: 983 SSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANN 1042
Query: 301 LEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILD-----GKIFELTELRDNLAKLL 351
E ++ DL ++L S + E ++ + LL ++ K+ E+ L AK +
Sbjct: 1043 FEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAM 1098
Score = 42.0 bits (97), Expect = 8e-04
Identities = 33/170 (19%), Positives = 84/170 (49%), Gaps = 9/170 (5%)
Query: 186 ELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAER---LHKRVTELECVSSQANAV 242
E AT +L L + +++ Q+L +++A++ ++ + + E + + N
Sbjct: 1116 EHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQK 1175
Query: 243 HTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLE 302
T+K N I++LE+ +K+++++ E L++EI + + +Q + K++++ ++ K
Sbjct: 1176 LTNK---NNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKK-- 1230
Query: 303 GQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLE 352
+L+D +Q Q + + L+ + ++ +L E+ K+ E
Sbjct: 1231 -ELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHE 1279
Score = 40.8 bits (94), Expect = 0.002
Identities = 63/278 (22%), Positives = 111/278 (39%), Gaps = 44/278 (15%)
Query: 101 EKFQEFKEAARLAKEKSQEKMELTSTPSQE----SAGGDLQSPLTPESINGTDDERTP-- 154
EK + K A AK++ + T T +E + D S + I G + +
Sbjct: 965 EKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLL 1024
Query: 155 DVTQNSEPRAEPTQNALPFSHS----SAISKHWEAELATLKGNNAKLTAALLESTANVKQ 210
+ + SE + A F H + ++ + T+ +N L A + +N K
Sbjct: 1025 EYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKL 1084
Query: 211 WKQQLAAYQE---------EAERLHKR---------VTELECVSSQANAVHTHKTELNQT 252
+ Q+ Q EAE+L K V ELE + Q + K +L +T
Sbjct: 1085 LEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQ---LQKEKKQLQKT 1141
Query: 253 IQELEETLKLKEEEIERLKQEI-DNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQR 311
+QEL E +K ++ + EI D R ++E LT K ++E DLEQ
Sbjct: 1142 MQEL-ELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIE-----------DLEQE 1189
Query: 312 LEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAK 349
++ + +QE + + +L + + T+++ L K
Sbjct: 1190 IKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVK 1227
Score = 40.0 bits (92), Expect = 0.003
Identities = 47/207 (22%), Positives = 81/207 (39%), Gaps = 15/207 (7%)
Query: 156 VTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQL 215
V Q E + Q + A SK E + L+ A L L S V+ +K QL
Sbjct: 1211 VQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQ---ASLKGELEASQQQVEVYKIQL 1267
Query: 216 AAYQEEAERLHKRV-TELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEI 274
A E ++H+ + T E +A T L + + + E E K +
Sbjct: 1268 AEITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRV 1327
Query: 275 DNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQN-------EQEAFRNNLK 327
N + Q+ + + + + + LE + L+ +L+ SQN E + ++
Sbjct: 1328 HNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHD 1387
Query: 328 TLLE----ILDGKIFELTELRDNLAKL 350
TLLE +L + + ELR+ L +
Sbjct: 1388 TLLERHNKMLQETVSKEAELREKLCSI 1414
Score = 39.3 bits (90), Expect = 0.005
Identities = 43/184 (23%), Positives = 89/184 (48%), Gaps = 17/184 (9%)
Query: 186 ELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTH 245
E+ +LK + K + L E+ + + ++ + E + L ++ L+ +A +
Sbjct: 425 EVQSLKEQHQKEISELNETFLSDSEKEKLTLMF--EIQGLKEQCENLQQEKQEAILNYES 482
Query: 246 KTELNQTIQ-ELEETLKLKEEEIERLKQE-IDNARELQE-------QRDSLTQKLQEVEI 296
E+ + +Q EL E+ +E E +KQ+ + ELQ+ ++D+L + + ++
Sbjct: 483 LREIMEILQTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQG 542
Query: 297 RNKDLEGQ---LSDLEQRLEKSQNEQEAFRNNLK---TLLEILDGKIFELTELRDNLAKL 350
N+ L Q + +LE ++ Q + + +L T+L+ L+GKI LTE +D+
Sbjct: 543 ENEKLLSQQELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINK 602
Query: 351 LECS 354
L+ S
Sbjct: 603 LKNS 606
Score = 35.0 bits (79), Expect = 0.10
Identities = 39/155 (25%), Positives = 73/155 (47%), Gaps = 34/155 (21%)
Query: 229 VTELECVSSQANAVHTHKTEL----NQTIQELEETLK-LKEEEIERLKQEIDNARELQEQ 283
V L+ V ++ K L ++ + ELE+ +K L+EE + + ++ R+ +++
Sbjct: 780 VNVLQAVGESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQE 839
Query: 284 RDSLTQKLQEVE---------------------IRNKDLEGQLSDLEQRLEKSQ--NEQE 320
+ L ++L+E++ + N++L Q+ ++ Q KS+ NE+E
Sbjct: 840 KVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKE 899
Query: 321 AF----RNNLKTLLE--ILDGKIFELTELRDNLAK 349
NLK LLE L + EL L+D+LAK
Sbjct: 900 KCFIKEHENLKPLLEQKELRDRRAELILLKDSLAK 934
Score = 32.3 bits (72), Expect = 0.66
Identities = 50/242 (20%), Positives = 92/242 (38%), Gaps = 54/242 (22%)
Query: 105 EFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRA 164
E E + +L + G + Q + ++ T DE+ VTQ
Sbjct: 165 ELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDEKKETVTQ------ 218
Query: 165 EPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAER 224
QN + A S+H++ + +L+ +L A E VK+ Q+ A +E E
Sbjct: 219 --LQNII-----EANSQHYQKNINSLQEELLQLKAIHQEE---VKELMCQIEASAKEHEA 268
Query: 225 LHKRVTEL------ECVSSQANAVHTHKTEL----------------------------- 249
++ EL +C +S+ N ++ EL
Sbjct: 269 EINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQDNQICSILLQENTFVEQ 328
Query: 250 --NQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQ-EVEIRNKDLEGQLS 306
N+ ++ LE+TLK E + LK E+ L+ + + Q ++ E +DLE +++
Sbjct: 329 VVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKIN 388
Query: 307 DL 308
+L
Sbjct: 389 EL 390
Score = 30.8 bits (68), Expect = 1.9
Identities = 26/111 (23%), Positives = 51/111 (45%), Gaps = 17/111 (15%)
Query: 221 EAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETL-------KLKEEEIERL--- 270
E + L R EL + + K + +++ELEE + K KEE+I ++
Sbjct: 914 EQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLV 973
Query: 271 ----KQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQN 317
K+E+D++R ++ ++ ++L+ + L + DL Q E +N
Sbjct: 974 AVKAKKELDSSR---KETQTVKEELESLRSEKDQLSASMRDLIQGAESYKN 1021
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 55.5 bits (132), Expect = 7e-08
Identities = 67/275 (24%), Positives = 128/275 (46%), Gaps = 34/275 (12%)
Query: 98 KFAEKFQEFKEAARLAKEKSQEKMELTSTPSQ--------ESAGGDLQSP-LTPESINGT 148
+ AE ++ KE ++ +EK Q+ + + S+ E+ +L++ LT E +
Sbjct: 1121 RLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETE 1180
Query: 149 DDERTPDVTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANV 208
E + +N E T+ + K +E E L+G ++ A L++ +
Sbjct: 1181 RLELAQKLNENYEEVKSITKERKVLKE---LQKSFETERDHLRGYIREIEATGLQTKEEL 1237
Query: 209 KQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIE 268
K L +QE + L + V+E A ++T E + T +L+E + + EE E
Sbjct: 1238 KIAHIHLKEHQETIDELRRSVSE-----KTAQIINTQDLEKSHT--KLQEEIPVLHEEQE 1290
Query: 269 RLKQEIDNARELQEQRDSLTQ-KLQEVEIRNKD------LEGQLSDLEQRLEKSQNEQEA 321
L N +E+ E ++++ + +L + KD +E + L ++ ++SQ E ++
Sbjct: 1291 LLP----NVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKS 1346
Query: 322 F---RNNLKTLLEILDGKIFELTE-LRDNLAKLLE 352
R+NLKT+ E L+ K +L E +R+ LAK+ E
Sbjct: 1347 LTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQE 1381
Score = 52.8 bits (125), Expect = 5e-07
Identities = 42/164 (25%), Positives = 81/164 (49%), Gaps = 15/164 (9%)
Query: 190 LKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTEL 249
L+ +NAKL + E AN + QL +++ K+V+E+E + Q ++L
Sbjct: 1811 LENSNAKLQEKIQELKAN----EHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKL 1866
Query: 250 NQTIQELEETLKLKEEEIERLKQEIDNARELQE----QRDSLTQKLQEVEIRNKDLEGQL 305
L + L EE++ + +E DN R ++E +RD L + LQE + R DLE
Sbjct: 1867 EIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKAR--DLE--- 1921
Query: 306 SDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAK 349
++Q L+ ++ + + + L E + K ++++++ +L K
Sbjct: 1922 --IQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDK 1963
Score = 50.1 bits (118), Expect = 3e-06
Identities = 57/284 (20%), Positives = 116/284 (40%), Gaps = 41/284 (14%)
Query: 96 LSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDERTPD 155
L+K + + KEA + ++ +E + T QES QS E D+E T
Sbjct: 1347 LTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEK----DNETTKI 1402
Query: 156 VTQNSEPRAEPT------------QNALPFSHSSA------------ISKHWEAELATLK 191
V++ + + + + L SH + + ++E LK
Sbjct: 1403 VSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLK 1462
Query: 192 GNNAKLTAALLESTANVKQ----WKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKT 247
N ++ A LE+ +K K+Q E L ++ TE+ + Q A++
Sbjct: 1463 ENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQ 1522
Query: 248 ELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSD 307
Q I E EE +K +I ++++++ ++ +E R + LQ + E ++ +
Sbjct: 1523 NKIQEIYEKEEQFNIK--QISEVQEKVNELKQFKEHRKAKDSALQSI-------ESKMLE 1573
Query: 308 LEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLL 351
L RL++SQ E + + + + + E +L++N +++
Sbjct: 1574 LTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIV 1617
Score = 49.7 bits (117), Expect = 4e-06
Identities = 39/139 (28%), Positives = 71/139 (51%), Gaps = 11/139 (7%)
Query: 202 LESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLK 261
LES + KQ KQ L + E L + E + S+ + EL T +++E ++
Sbjct: 614 LESIEDPKQMKQTL--FDAETVALDAK-RESAFLRSENLELKEKMKELATTYKQMENDIQ 670
Query: 262 LKEEEIE-RLKQEIDNARELQEQRDSLTQ-------KLQEVEIRNKDLEGQLSDLEQRLE 313
L + ++E + K ++D +ELQ + +T+ K+ + + N +LEG+++DL++ L
Sbjct: 671 LYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELN 730
Query: 314 KSQNEQEAFRNNLKTLLEI 332
K E EA R + L E+
Sbjct: 731 KEVEENEALREEVILLSEL 749
Score = 48.5 bits (114), Expect = 9e-06
Identities = 36/149 (24%), Positives = 76/149 (51%), Gaps = 8/149 (5%)
Query: 186 ELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANA-VHT 244
+LAT + N ++Q+ EE ER+++ + L + + ++ +
Sbjct: 804 DLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGA 863
Query: 245 HKTELNQTIQELEETLKLKEE---EIERLKQEIDNA----RELQEQRDSLTQKLQEVEIR 297
KTEL+ QEL+E + +E E+E+LK++++N + ++ ++ +T+KLQ+
Sbjct: 864 LKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEE 923
Query: 298 NKDLEGQLSDLEQRLEKSQNEQEAFRNNL 326
K L + DL+Q E Q E++ ++++
Sbjct: 924 VKTLTQEKDDLKQLQESLQIERDQLKSDI 952
Score = 45.8 bits (107), Expect = 6e-05
Identities = 33/147 (22%), Positives = 67/147 (45%), Gaps = 4/147 (2%)
Query: 184 EAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVH 243
E EL+ A++ L E + +++ +QQL QEE + K++ E+E + ++
Sbjct: 1112 EGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKE 1171
Query: 244 THKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQE----QRDSLTQKLQEVEIRNK 299
+ EL + L EE++ + +E +ELQ+ +RD L ++E+E
Sbjct: 1172 LTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGL 1231
Query: 300 DLEGQLSDLEQRLEKSQNEQEAFRNNL 326
+ +L L++ Q + R ++
Sbjct: 1232 QTKEELKIAHIHLKEHQETIDELRRSV 1258
Score = 42.7 bits (99), Expect = 5e-04
Identities = 50/250 (20%), Positives = 105/250 (42%), Gaps = 37/250 (14%)
Query: 95 HLSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDERTP 154
HL + E E + + S++ ++ +T E + LQ + + + E P
Sbjct: 1243 HLKEHQETIDELRRSV------SEKTAQIINTQDLEKSHTKLQEEIP---VLHEEQELLP 1293
Query: 155 DVTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQ 214
+V + SE + T N L + +K LA ++ +L ES +K ++
Sbjct: 1294 NVKEVSE--TQETMNELELLTEQSTTKD-STTLARIEMERLRLNEKFQESQEEIKSLTKE 1350
Query: 215 ---LAAYQEEAERLHKRVTELECVSSQANAVHTHKT--ELNQTIQELEETLKLKEE---- 265
L +E E H ++ E H +T ++ ++ + E++L +KE+
Sbjct: 1351 RDNLKTIKEALEVKHDQLKE-----------HIRETLAKIQESQSKQEQSLNMKEKDNET 1399
Query: 266 -----EIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQE 320
E+E+ K + ++ + L+++LQE K + + DL++ E Q+E +
Sbjct: 1400 TKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESD 1459
Query: 321 AFRNNLKTLL 330
+ N+K ++
Sbjct: 1460 QLKENIKEIV 1469
Score = 42.7 bits (99), Expect = 5e-04
Identities = 43/186 (23%), Positives = 84/186 (45%), Gaps = 13/186 (6%)
Query: 176 SSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAE-RLHKRVTEL-- 232
S+ ISK WE +L +LK N KL ++ Q Q+ + R T+L
Sbjct: 2321 SATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTT 2380
Query: 233 ECVSSQANAVHTHKTEL---NQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQ 289
E + N++H K I ++++ L++ + I +L+ ++ + + E+ Q
Sbjct: 2381 EKIRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQ 2440
Query: 290 KLQE-VEIRNKDLEGQLSDLEQR-----LEKSQNEQEAFRNNLKTLLEILDGKIFELTEL 343
LQ+ V + K + ++ DL+ + LEK +N +E F + ++ + + L
Sbjct: 2441 VLQDKVALGAKPYKEEIEDLKMKLVKIDLEKMKNAKE-FEKEISATKATVEYQKEVIRLL 2499
Query: 344 RDNLAK 349
R+NL +
Sbjct: 2500 RENLRR 2505
Score = 41.6 bits (96), Expect = 0.001
Identities = 37/144 (25%), Positives = 68/144 (47%), Gaps = 14/144 (9%)
Query: 223 ERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQE 282
E + K +L S + + E+ K+ EE ER+ QEI N + +
Sbjct: 796 EEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQ 855
Query: 283 QRDS--------LTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFR--NNLKTLL-E 331
+ DS L+ K QE++ + ++++ +L+++EQ E+ +N + KTL+ E
Sbjct: 856 KFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITE 915
Query: 332 ILDGKIFE---LTELRDNLAKLLE 352
L + E LT+ +D+L +L E
Sbjct: 916 KLQQTLEEVKTLTQEKDDLKQLQE 939
Score = 39.7 bits (91), Expect = 0.004
Identities = 39/182 (21%), Positives = 88/182 (48%), Gaps = 19/182 (10%)
Query: 184 EAELAT----LKGNNAKLTAALLESTANVKQWK-QQLAAYQEEAERLHKRVTELECVSSQ 238
E E++T L+ N KL + E +Q+ +Q++ QE+ L + + S
Sbjct: 1504 ETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSA 1563
Query: 239 ANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRN 298
++ + EL +QE +E +++ +E E +K+ LQ +RD L + +E+ +
Sbjct: 1564 LQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRV---QEALQIERDQLKENTKEIVAKM 1620
Query: 299 KDLEGQ---------LSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTE-LRDNLA 348
K+ + + +++ ++++ + ++ +E F K LE ++ + LT+ L +NL
Sbjct: 1621 KESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQ-KLNLENIETENIRLTQILHENLE 1679
Query: 349 KL 350
++
Sbjct: 1680 EM 1681
Score = 39.3 bits (90), Expect = 0.005
Identities = 40/177 (22%), Positives = 83/177 (46%), Gaps = 15/177 (8%)
Query: 187 LATLKGNNAKLTAAL---LESTANVKQWKQQLAAYQEEA--------ERLHKRVTELECV 235
L ++ N +LT L LE +V + + L + +E E L + +T
Sbjct: 1660 LENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEK 1719
Query: 236 SSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVE 295
+ VH H E +TI +L + K EI ++++++++ + + +D Q +E+
Sbjct: 1720 QEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQ--EELR 1777
Query: 296 IRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFE-LTELRDNLAKLL 351
I + L+ Q ++ +L +E+ +N++ LE + K+ E + EL+ N +L+
Sbjct: 1778 IAHMHLKEQQETID-KLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLI 1833
Score = 38.9 bits (89), Expect = 0.007
Identities = 56/283 (19%), Positives = 114/283 (40%), Gaps = 31/283 (10%)
Query: 101 EKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNS 160
++FQ FK ++K + +E +QE ++ S+ E + +
Sbjct: 817 QEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQ 876
Query: 161 EPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVK---QWKQQLAA 217
E E + ++ ++ L T++ +T L ++ VK Q K L
Sbjct: 877 EKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQ 936
Query: 218 YQE----EAERLHKRVTE---------------LECVSSQANAVHTHKTELNQTIQE--- 255
QE E ++L + + LE + ++T K+++++ +
Sbjct: 937 LQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLH 996
Query: 256 LEETLKLKEEEIERLKQEIDNARELQEQR-DSLTQKLQEVEIRNKD-----LEGQLSDLE 309
+EE ++E ++ ID ++L+ + +LT +++ EI + L + ++L+
Sbjct: 997 MEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQ 1056
Query: 310 QRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLE 352
Q LE E+E + +LK +E+ EL L D L K E
Sbjct: 1057 QMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQE 1099
Score = 38.1 bits (87), Expect = 0.012
Identities = 31/116 (26%), Positives = 53/116 (45%), Gaps = 10/116 (8%)
Query: 214 QLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQE 273
QL +E+ HK++ E+E + Q A + + +L + L EEI + +E
Sbjct: 1981 QLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKE 2040
Query: 274 IDNARELQE----QRDSLTQKLQEVEIRN------KDLEGQLSDLEQRLEKSQNEQ 319
D R ++E +RD L+E+ R+ K + LSD +Q L +S E+
Sbjct: 2041 RDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLTESLREK 2096
Score = 36.6 bits (83), Expect = 0.035
Identities = 36/136 (26%), Positives = 68/136 (50%), Gaps = 12/136 (8%)
Query: 212 KQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLK 271
KQQ QE+ + K+ EL + V E +Q +QE ++ L +EE+ ++
Sbjct: 1096 KQQEIVAQEKNHAI-KKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQ 1154
Query: 272 QEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLE 331
++I+ + ++L +L+ E+ + +E + +L Q+L ++ E ++ K L E
Sbjct: 1155 KKIN-------EIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKE 1207
Query: 332 ILDGKIFELTELRDNL 347
+ K FE TE RD+L
Sbjct: 1208 L--QKSFE-TE-RDHL 1219
Score = 35.0 bits (79), Expect = 0.10
Identities = 58/277 (20%), Positives = 107/277 (38%), Gaps = 47/277 (16%)
Query: 87 GLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESIN 146
G+ + +S + + +A + K QE++ + +E T + +
Sbjct: 1742 GIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQE-------TIDKLR 1794
Query: 147 GTDDERTPDVTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTA 206
G E+T D N + E + L K E +L TLK + + + E
Sbjct: 1795 GIVSEKT-DKLSNMQKDLENSNAKLQEKIQEL--KANEHQLITLKKDVNETQKKVSEMEQ 1851
Query: 207 NVKQWKQQ---LAAYQEE----AERLHKRVTELECVSSQANAVH----THKTELNQTIQE 255
KQ K Q L+ + E A++LH+ + E++ V + + + T K E +Q +
Sbjct: 1852 LKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKES 1911
Query: 256 LEETL-------------------------KLKEEEIERLKQEIDNARELQEQRDSLTQK 290
L+ET KL+E+ E+ Q D ++L + +D L +K
Sbjct: 1912 LQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKK 1971
Query: 291 LQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLK 327
+QE++ + L D+ K NE E + +
Sbjct: 1972 IQELQKKELQLLRVKEDVNMS-HKKINEMEQLKKQFE 2007
Score = 35.0 bits (79), Expect = 0.10
Identities = 31/142 (21%), Positives = 63/142 (44%), Gaps = 9/142 (6%)
Query: 212 KQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTE-LNQTIQELEETLKLKEEEIERL 270
K Q QEE H + E + + + + KT+ L+ ++LE + +E+I+ L
Sbjct: 1766 KAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQEL 1825
Query: 271 KQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLL 330
K L++ + +K+ E+E K ++ Q L + ++ N + NL+ +
Sbjct: 1826 KANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMK 1885
Query: 331 EILDGKIFELTELRDNLAKLLE 352
++ + RDNL ++ E
Sbjct: 1886 SVM--------KERDNLRRVEE 1899
Score = 34.7 bits (78), Expect = 0.13
Identities = 29/126 (23%), Positives = 53/126 (42%), Gaps = 4/126 (3%)
Query: 208 VKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEI 267
V Q K + E R R+ E+E + + K + +QE ++ K EI
Sbjct: 1101 VAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEI 1160
Query: 268 ERLKQEIDN----ARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFR 323
E LK E+ N ++ +R L QKL E K + + L++ + + E++ R
Sbjct: 1161 ENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLR 1220
Query: 324 NNLKTL 329
++ +
Sbjct: 1221 GYIREI 1226
Score = 33.5 bits (75), Expect = 0.30
Identities = 53/248 (21%), Positives = 102/248 (41%), Gaps = 22/248 (8%)
Query: 96 LSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQ-ESAGGDLQSPLTPESINGTDDERTP 154
++K E +E K A KE+ + EL S+ E+ +Q L E+IN +
Sbjct: 1469 VAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQL--EAINDKLQNKIQ 1526
Query: 155 DVTQNSEPR-----AEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVK 209
++ + E +E + K ++ L +++ +LT L ES ++
Sbjct: 1527 EIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQ 1586
Query: 210 -------QWKQQLAAYQEEAERLHKRVTELECV---SSQANAVHTHKTELNQTIQELEET 259
+ K+ A Q E ++L + E+ S + T +N+T +++ E
Sbjct: 1587 IMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEI 1646
Query: 260 LKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQ 319
LKE+ E K ++N ++ + LTQ L E + + + DL E + E+
Sbjct: 1647 EHLKEQ-FETQKLNLEN---IETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVER 1702
Query: 320 EAFRNNLK 327
+ + NL+
Sbjct: 1703 DQLKENLR 1710
Score = 31.2 bits (69), Expect = 1.5
Identities = 27/118 (22%), Positives = 55/118 (46%), Gaps = 8/118 (6%)
Query: 220 EEAERLHKRVTELECVSSQANA------VHTHKTELNQTIQELEETLKLKEEEIERLKQE 273
E ER K+ E++ + +N + +L + E L+ KE++I++L++
Sbjct: 538 EALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEY 597
Query: 274 IDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLE 331
ID +++L+ + L+ L+ +E K ++ L D E ++ E R+ L E
Sbjct: 598 ID-SQKLENIKMDLSYSLESIE-DPKQMKQTLFDAETVALDAKRESAFLRSENLELKE 653
>gi|110611218 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 55.1 bits (131), Expect = 1e-07
Identities = 44/162 (27%), Positives = 81/162 (50%), Gaps = 12/162 (7%)
Query: 176 SSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECV 235
+S + AELA L+ +K++ L+E + V+Q +QQ A + +A K+V +L+
Sbjct: 380 TSQVESKQNAELAKLRQELSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVLQLQ-- 437
Query: 236 SSQANAVHTHKTE-LNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQ-- 292
A H E L + + E+ L + L+ + + A+E Q+Q L KLQ
Sbjct: 438 -----ASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSS 492
Query: 293 EVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILD 334
E E+R+K E LS L +L++++ E ++++ +L+
Sbjct: 493 EAEVRSKCEE--LSGLHGQLQEARAENSQLTERIRSIEALLE 532
Score = 33.9 bits (76), Expect = 0.23
Identities = 54/245 (22%), Positives = 109/245 (44%), Gaps = 37/245 (15%)
Query: 113 AKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTD-----DERTPDVTQNSEPRAEPT 167
AKE+S++++ L + E+ L N T+ E+ P + ++ AEP+
Sbjct: 615 AKEESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHPPAPAEPS 674
Query: 168 QNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHK 227
S SK EAE T + L+ A Q++ LA + L K
Sbjct: 675 --------SDLASKLREAEE----------TQSTLQ--AECDQYRSILAETEGMLRDLQK 714
Query: 228 RVTELECV-SSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDS 286
V E E V ++ A + +Q+ T+K EE +E+LK E++++ +++E
Sbjct: 715 SVEEEEQVWRAKVGAAE-------EELQKSRVTVKHLEEIVEKLKGELESSDQVREHTSH 767
Query: 287 LTQKLQE----VEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTE 342
L +L++ ++ +++ L Q L +SQ++ +A ++ + + L +L+E
Sbjct: 768 LEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSE 827
Query: 343 LRDNL 347
++ ++
Sbjct: 828 MKSHV 832
Score = 32.7 bits (73), Expect = 0.51
Identities = 45/200 (22%), Positives = 81/200 (40%), Gaps = 33/200 (16%)
Query: 161 EPRAEPTQNALPFSHSSAISKHWEAELATLKGNN-AKLTAALLESTANVKQWKQQLAAY- 218
+ R + L + SS S +AE A + A+L + L S A V+ ++L+
Sbjct: 448 QKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEAEVRSKCEELSGLH 507
Query: 219 ------QEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEET-LKLKEEEIERLK 271
+ E +L +R+ +E + A + +Q + ++T LK E ++ L+
Sbjct: 508 GQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQTRLKELESQVSGLE 567
Query: 272 QEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLE 331
+E RE EQ+ +++N DL EK+ EA L T +
Sbjct: 568 KEAIELREAVEQQ----------KVKNNDLR----------EKNWKAMEA----LATAEQ 603
Query: 332 ILDGKIFELTELRDNLAKLL 351
K+ LT+ ++ K L
Sbjct: 604 ACKEKLHSLTQAKEESEKQL 623
Score = 32.7 bits (73), Expect = 0.51
Identities = 42/196 (21%), Positives = 78/196 (39%), Gaps = 18/196 (9%)
Query: 174 SHSSA-ISKHWEAELATLKGNNAKLTAAL----LESTANVKQWKQQLAAYQEEAERLHKR 228
SH A + KH A A + N AK A L LES + + K + +E + ++
Sbjct: 766 SHLEAELEKHMAAASAECQ-NYAKEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQ 824
Query: 229 VTELE------------CVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDN 276
++E++ S +A +L ++ E L+ ++ + ++L E +
Sbjct: 825 LSEMKSHVEDGDIAGAPASSPEAPPAEQDPVQLKTQLEWTEAILEDEQTQRQKLTAEFEE 884
Query: 277 ARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGK 336
A+ + +KL+ + S L++RLEK + L E+L
Sbjct: 885 AQTSACRLQEELEKLRTAGPLESSETEEASQLKERLEKEKKLTSDLGRAATRLQELLKTT 944
Query: 337 IFELTELRDNLAKLLE 352
+L +D + KL E
Sbjct: 945 QEQLAREKDTVKKLQE 960
>gi|110611220 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 55.1 bits (131), Expect = 1e-07
Identities = 44/162 (27%), Positives = 81/162 (50%), Gaps = 12/162 (7%)
Query: 176 SSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECV 235
+S + AELA L+ +K++ L+E + V+Q +QQ A + +A K+V +L+
Sbjct: 380 TSQVESKQNAELAKLRQELSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVLQLQ-- 437
Query: 236 SSQANAVHTHKTE-LNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQ-- 292
A H E L + + E+ L + L+ + + A+E Q+Q L KLQ
Sbjct: 438 -----ASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSS 492
Query: 293 EVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILD 334
E E+R+K E LS L +L++++ E ++++ +L+
Sbjct: 493 EAEVRSKCEE--LSGLHGQLQEARAENSQLTERIRSIEALLE 532
Score = 33.9 bits (76), Expect = 0.23
Identities = 54/245 (22%), Positives = 109/245 (44%), Gaps = 37/245 (15%)
Query: 113 AKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTD-----DERTPDVTQNSEPRAEPT 167
AKE+S++++ L + E+ L N T+ E+ P + ++ AEP+
Sbjct: 615 AKEESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHPPAPAEPS 674
Query: 168 QNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHK 227
S SK EAE T + L+ A Q++ LA + L K
Sbjct: 675 --------SDLASKLREAEE----------TQSTLQ--AECDQYRSILAETEGMLRDLQK 714
Query: 228 RVTELECV-SSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDS 286
V E E V ++ A + +Q+ T+K EE +E+LK E++++ +++E
Sbjct: 715 SVEEEEQVWRAKVGAAE-------EELQKSRVTVKHLEEIVEKLKGELESSDQVREHTSH 767
Query: 287 LTQKLQE----VEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTE 342
L +L++ ++ +++ L Q L +SQ++ +A ++ + + L +L+E
Sbjct: 768 LEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSE 827
Query: 343 LRDNL 347
++ ++
Sbjct: 828 MKSHV 832
Score = 32.7 bits (73), Expect = 0.51
Identities = 45/200 (22%), Positives = 81/200 (40%), Gaps = 33/200 (16%)
Query: 161 EPRAEPTQNALPFSHSSAISKHWEAELATLKGNN-AKLTAALLESTANVKQWKQQLAAY- 218
+ R + L + SS S +AE A + A+L + L S A V+ ++L+
Sbjct: 448 QKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEAEVRSKCEELSGLH 507
Query: 219 ------QEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEET-LKLKEEEIERLK 271
+ E +L +R+ +E + A + +Q + ++T LK E ++ L+
Sbjct: 508 GQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQTRLKELESQVSGLE 567
Query: 272 QEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLE 331
+E RE EQ+ +++N DL EK+ EA L T +
Sbjct: 568 KEAIELREAVEQQ----------KVKNNDLR----------EKNWKAMEA----LATAEQ 603
Query: 332 ILDGKIFELTELRDNLAKLL 351
K+ LT+ ++ K L
Sbjct: 604 ACKEKLHSLTQAKEESEKQL 623
Score = 32.7 bits (73), Expect = 0.51
Identities = 42/196 (21%), Positives = 78/196 (39%), Gaps = 18/196 (9%)
Query: 174 SHSSA-ISKHWEAELATLKGNNAKLTAAL----LESTANVKQWKQQLAAYQEEAERLHKR 228
SH A + KH A A + N AK A L LES + + K + +E + ++
Sbjct: 766 SHLEAELEKHMAAASAECQ-NYAKEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQ 824
Query: 229 VTELE------------CVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDN 276
++E++ S +A +L ++ E L+ ++ + ++L E +
Sbjct: 825 LSEMKSHVEDGDIAGAPASSPEAPPAEQDPVQLKTQLEWTEAILEDEQTQRQKLTAEFEE 884
Query: 277 ARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGK 336
A+ + +KL+ + S L++RLEK + L E+L
Sbjct: 885 AQTSACRLQEELEKLRTAGPLESSETEEASQLKERLEKEKKLTSDLGRAATRLQELLKTT 944
Query: 337 IFELTELRDNLAKLLE 352
+L +D + KL E
Sbjct: 945 QEQLAREKDTVKKLQE 960
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 55.1 bits (131), Expect = 1e-07
Identities = 60/263 (22%), Positives = 120/263 (45%), Gaps = 27/263 (10%)
Query: 105 EFKEAARLAKEKSQE-KMELTSTPSQESAGGD--LQSPLTPESINGTDDERTPDVTQNSE 161
E + A R+A++ + + + ++T + +A D L+ +T +++ T ER D+ E
Sbjct: 1554 ELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALK-TQHER--DLQGRDE 1610
Query: 162 PRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAY--- 218
E + + + + E + TL AA + +++ K Q+A+
Sbjct: 1611 AGEERRRQLAKQLRDAEVERDEERKQRTLA------VAARKKLEGELEELKAQMASAGQG 1664
Query: 219 -QEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEI--- 274
+E ++L K +++ + + T + E+ +E E+ LK E E+ RL++E+
Sbjct: 1665 KEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAAS 1724
Query: 275 DNAR-ELQEQRDSLTQKLQEVEI-------RNKDLEGQLSDLEQRLEKSQNEQEAFRNNL 326
D AR + Q+ RD + ++ + + LEG+L LE+ LE+ Q+ E +
Sbjct: 1725 DRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRY 1784
Query: 327 KTLLEILDGKIFELTELRDNLAK 349
+ LL ++ EL+ R AK
Sbjct: 1785 RKLLLQVESLTTELSAERSFSAK 1807
Score = 44.3 bits (103), Expect = 2e-04
Identities = 59/225 (26%), Positives = 86/225 (38%), Gaps = 53/225 (23%)
Query: 161 EPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQE 220
+ RA+ Q SA E+ L+G A+L ++ + A +E
Sbjct: 880 QARAQELQKVQELQQQSA------REVGELQGRVAQLEEERARLAEQLRAEAELCAEAEE 933
Query: 221 EAERLHKRVTELECVSSQANA-----------VHTHKTELNQTIQELEETLKLKEEEIER 269
RL R ELE V S+ A + T K L Q IQELE L+ +E ++
Sbjct: 934 TRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQK 993
Query: 270 LKQE------------------IDNARELQEQRDSLTQKLQE-----------VEIRNK- 299
L+ E D +L ++R L +L E V+ NK
Sbjct: 994 LQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKL 1053
Query: 300 --DLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTE 342
E ++D+E RL K +E R L+ L LDG+ EL E
Sbjct: 1054 RLKYEATIADMEDRLRK----EEKGRQELEKLKRRLDGESSELQE 1094
Score = 40.0 bits (92), Expect = 0.003
Identities = 41/178 (23%), Positives = 79/178 (44%), Gaps = 17/178 (9%)
Query: 175 HSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELEC 234
H + H EAE +G KL + + A +K++++ L +++ +L K LE
Sbjct: 976 HIQELEAHLEAE----EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLED 1031
Query: 235 VSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEV 294
++ ++ Q EE K+K RLK E A +++++ + QE+
Sbjct: 1032 RLAEFSS------------QAAEEEEKVKSLNKLRLKYEATIA-DMEDRLRKEEKGRQEL 1078
Query: 295 EIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLE 352
E + L+G+ S+L++++ + Q E R L E L + + A+LL+
Sbjct: 1079 EKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLK 1136
Score = 38.5 bits (88), Expect = 0.009
Identities = 31/121 (25%), Positives = 58/121 (47%), Gaps = 16/121 (13%)
Query: 224 RLHKRVTELECVSSQANAVHTHKTELNQTIQELEE------------TLKLKEEEI---E 268
RL +V L V+ Q + EL Q +QEL++ +L+EE E
Sbjct: 861 RLFTKVKPLLQVTRQDEVLQARAQEL-QKVQELQQQSAREVGELQGRVAQLEEERARLAE 919
Query: 269 RLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKT 328
+L+ E + E +E R L + QE+E+ +LE ++ + E+ + Q E++ + +++
Sbjct: 920 QLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQE 979
Query: 329 L 329
L
Sbjct: 980 L 980
Score = 37.7 bits (86), Expect = 0.016
Identities = 60/250 (24%), Positives = 99/250 (39%), Gaps = 24/250 (9%)
Query: 96 LSKFAEKFQEFK------EAARLAKEK--SQEKMELTS--TPSQESAGGDLQSPLTPESI 145
L + AE+ ++ + E RLA E S+ + EL+S T QE + L + +
Sbjct: 1230 LGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEV 1289
Query: 146 NGT--DDERT----PDVTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTA 199
G D ER + Q ++ E AL + S I EL++ +
Sbjct: 1290 QGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTI--RLSKELSSTEAQLHDAQE 1347
Query: 200 ALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEET 259
L E T ++ A + EA L +++ E +A EL +L E
Sbjct: 1348 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGR------ELQTAQAQLSEW 1401
Query: 260 LKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQ 319
+ +EEE L+ + R + ++LTQ+L E LE L+Q L+ + +
Sbjct: 1402 RRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL 1461
Query: 320 EAFRNNLKTL 329
E R + TL
Sbjct: 1462 EQQRQLVSTL 1471
Score = 35.8 bits (81), Expect = 0.060
Identities = 40/158 (25%), Positives = 67/158 (42%), Gaps = 12/158 (7%)
Query: 203 ESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQEL----EE 258
E A K KQ+ ++ E L ELE NA +++ Q + EL EE
Sbjct: 1155 ERVARTKAEKQR----RDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1210
Query: 259 TLKLKEEEIERLKQEIDNA-RELQEQRDSLTQKLQEVEIRNKDLEGQLSDLE---QRLEK 314
++ E ++ L+Q A EL EQ + + E LE ++S+L L+
Sbjct: 1211 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1270
Query: 315 SQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLE 352
++ E E R L+ L+ + G+ + R A+ L+
Sbjct: 1271 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1308
Score = 33.5 bits (75), Expect = 0.30
Identities = 35/173 (20%), Positives = 71/173 (41%), Gaps = 23/173 (13%)
Query: 186 ELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKR-VTELECVSSQANAVHT 244
EL+ + +AK + + +++ + +L A HK + LE +QA
Sbjct: 1797 ELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLE 1856
Query: 245 HKTE--------LNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEI 296
+T + + + L+E + EEE + D L +L++ +
Sbjct: 1857 QETRERILSGKLVRRAEKRLKEVVLQVEEE--------------RRVADQLRDQLEKGNL 1902
Query: 297 RNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAK 349
R K L+ QL + E+ ++Q + + L+ + E + E+T LR+ L +
Sbjct: 1903 RVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRR 1955
Score = 33.1 bits (74), Expect = 0.39
Identities = 37/155 (23%), Positives = 65/155 (41%), Gaps = 10/155 (6%)
Query: 184 EAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVH 243
EAE A L+ + AA + ++ + QL+ ++ E + LE
Sbjct: 1367 EAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQE---EEAGALEAGEEARRRAA 1423
Query: 244 THKTELNQTIQELEETLKLKEEEIERLKQEIDNA-RELQEQRDSLT------QKLQEVEI 296
L Q + E ET+ E RL+QE+D+A +L++QR ++ +K ++
Sbjct: 1424 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1483
Query: 297 RNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLE 331
K + + +R E E+EA +L LE
Sbjct: 1484 EEKAAVLRAVEERERAEAEGREREARALSLTRALE 1518
Score = 32.3 bits (72), Expect = 0.66
Identities = 49/250 (19%), Positives = 101/250 (40%), Gaps = 31/250 (12%)
Query: 107 KEAARLAKEKSQEKMELTSTPSQESAGGD-LQSPLTPESINGTDDERTPDVTQNSEPRAE 165
+ AAR A+ +Q E T T + G LQ L ++ D E+ + E +
Sbjct: 1420 RRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATM---DLEQQRQLVSTLEKKQR 1476
Query: 166 PTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERL 225
L ++ + E E A +G + A L A +EE E
Sbjct: 1477 KFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTR------------ALEEEQEAR 1524
Query: 226 HKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEE-------EIERLKQEIDNAR 278
+ + + ++ A+ + K ++ +++ ELE ++ E+ ++ L+ E+ A
Sbjct: 1525 EELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAE 1584
Query: 279 ELQEQRDSLTQKLQ---EVEIRNKDLEG-----QLSDLEQRLEKSQNEQEAFRNNLKTLL 330
+ + + + Q L+ E +++ +D G QL+ + E ++E+ R
Sbjct: 1585 DAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAAR 1644
Query: 331 EILDGKIFEL 340
+ L+G++ EL
Sbjct: 1645 KKLEGELEEL 1654
Score = 29.3 bits (64), Expect = 5.6
Identities = 24/92 (26%), Positives = 43/92 (46%), Gaps = 5/92 (5%)
Query: 196 KLTAALLESTANVKQWKQQLAAYQEEAERL----HKRVTELECVSSQANAVHTHKTELNQ 251
+L L + VKQ K+QL +EEA R + ELE V+ A +++ T L
Sbjct: 1892 QLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRN 1951
Query: 252 TIQELEETLKLKE-EEIERLKQEIDNARELQE 282
++ T + ++ RL++ + + E +E
Sbjct: 1952 RLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 1983
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 55.1 bits (131), Expect = 1e-07
Identities = 60/263 (22%), Positives = 120/263 (45%), Gaps = 27/263 (10%)
Query: 105 EFKEAARLAKEKSQE-KMELTSTPSQESAGGD--LQSPLTPESINGTDDERTPDVTQNSE 161
E + A R+A++ + + + ++T + +A D L+ +T +++ T ER D+ E
Sbjct: 1546 ELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALK-TQHER--DLQGRDE 1602
Query: 162 PRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAY--- 218
E + + + + E + TL AA + +++ K Q+A+
Sbjct: 1603 AGEERRRQLAKQLRDAEVERDEERKQRTLA------VAARKKLEGELEELKAQMASAGQG 1656
Query: 219 -QEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEI--- 274
+E ++L K +++ + + T + E+ +E E+ LK E E+ RL++E+
Sbjct: 1657 KEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAAS 1716
Query: 275 DNAR-ELQEQRDSLTQKLQEVEI-------RNKDLEGQLSDLEQRLEKSQNEQEAFRNNL 326
D AR + Q+ RD + ++ + + LEG+L LE+ LE+ Q+ E +
Sbjct: 1717 DRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRY 1776
Query: 327 KTLLEILDGKIFELTELRDNLAK 349
+ LL ++ EL+ R AK
Sbjct: 1777 RKLLLQVESLTTELSAERSFSAK 1799
Score = 44.3 bits (103), Expect = 2e-04
Identities = 59/225 (26%), Positives = 86/225 (38%), Gaps = 53/225 (23%)
Query: 161 EPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQE 220
+ RA+ Q SA E+ L+G A+L ++ + A +E
Sbjct: 872 QARAQELQKVQELQQQSA------REVGELQGRVAQLEEERARLAEQLRAEAELCAEAEE 925
Query: 221 EAERLHKRVTELECVSSQANA-----------VHTHKTELNQTIQELEETLKLKEEEIER 269
RL R ELE V S+ A + T K L Q IQELE L+ +E ++
Sbjct: 926 TRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQK 985
Query: 270 LKQE------------------IDNARELQEQRDSLTQKLQE-----------VEIRNK- 299
L+ E D +L ++R L +L E V+ NK
Sbjct: 986 LQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKL 1045
Query: 300 --DLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTE 342
E ++D+E RL K +E R L+ L LDG+ EL E
Sbjct: 1046 RLKYEATIADMEDRLRK----EEKGRQELEKLKRRLDGESSELQE 1086
Score = 40.0 bits (92), Expect = 0.003
Identities = 41/178 (23%), Positives = 79/178 (44%), Gaps = 17/178 (9%)
Query: 175 HSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELEC 234
H + H EAE +G KL + + A +K++++ L +++ +L K LE
Sbjct: 968 HIQELEAHLEAE----EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLED 1023
Query: 235 VSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEV 294
++ ++ Q EE K+K RLK E A +++++ + QE+
Sbjct: 1024 RLAEFSS------------QAAEEEEKVKSLNKLRLKYEATIA-DMEDRLRKEEKGRQEL 1070
Query: 295 EIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLE 352
E + L+G+ S+L++++ + Q E R L E L + + A+LL+
Sbjct: 1071 EKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLK 1128
Score = 38.5 bits (88), Expect = 0.009
Identities = 31/121 (25%), Positives = 58/121 (47%), Gaps = 16/121 (13%)
Query: 224 RLHKRVTELECVSSQANAVHTHKTELNQTIQELEE------------TLKLKEEEI---E 268
RL +V L V+ Q + EL Q +QEL++ +L+EE E
Sbjct: 853 RLFTKVKPLLQVTRQDEVLQARAQEL-QKVQELQQQSAREVGELQGRVAQLEEERARLAE 911
Query: 269 RLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKT 328
+L+ E + E +E R L + QE+E+ +LE ++ + E+ + Q E++ + +++
Sbjct: 912 QLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQE 971
Query: 329 L 329
L
Sbjct: 972 L 972
Score = 37.7 bits (86), Expect = 0.016
Identities = 60/250 (24%), Positives = 99/250 (39%), Gaps = 24/250 (9%)
Query: 96 LSKFAEKFQEFK------EAARLAKEK--SQEKMELTS--TPSQESAGGDLQSPLTPESI 145
L + AE+ ++ + E RLA E S+ + EL+S T QE + L + +
Sbjct: 1222 LGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEV 1281
Query: 146 NGT--DDERT----PDVTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTA 199
G D ER + Q ++ E AL + S I EL++ +
Sbjct: 1282 QGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTI--RLSKELSSTEAQLHDAQE 1339
Query: 200 ALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEET 259
L E T ++ A + EA L +++ E +A EL +L E
Sbjct: 1340 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGR------ELQTAQAQLSEW 1393
Query: 260 LKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQ 319
+ +EEE L+ + R + ++LTQ+L E LE L+Q L+ + +
Sbjct: 1394 RRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL 1453
Query: 320 EAFRNNLKTL 329
E R + TL
Sbjct: 1454 EQQRQLVSTL 1463
Score = 35.8 bits (81), Expect = 0.060
Identities = 40/158 (25%), Positives = 67/158 (42%), Gaps = 12/158 (7%)
Query: 203 ESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQEL----EE 258
E A K KQ+ ++ E L ELE NA +++ Q + EL EE
Sbjct: 1147 ERVARTKAEKQR----RDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1202
Query: 259 TLKLKEEEIERLKQEIDNA-RELQEQRDSLTQKLQEVEIRNKDLEGQLSDLE---QRLEK 314
++ E ++ L+Q A EL EQ + + E LE ++S+L L+
Sbjct: 1203 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1262
Query: 315 SQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLE 352
++ E E R L+ L+ + G+ + R A+ L+
Sbjct: 1263 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1300
Score = 33.5 bits (75), Expect = 0.30
Identities = 35/173 (20%), Positives = 71/173 (41%), Gaps = 23/173 (13%)
Query: 186 ELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKR-VTELECVSSQANAVHT 244
EL+ + +AK + + +++ + +L A HK + LE +QA
Sbjct: 1789 ELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLE 1848
Query: 245 HKTE--------LNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEI 296
+T + + + L+E + EEE + D L +L++ +
Sbjct: 1849 QETRERILSGKLVRRAEKRLKEVVLQVEEE--------------RRVADQLRDQLEKGNL 1894
Query: 297 RNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAK 349
R K L+ QL + E+ ++Q + + L+ + E + E+T LR+ L +
Sbjct: 1895 RVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRR 1947
Score = 33.1 bits (74), Expect = 0.39
Identities = 37/155 (23%), Positives = 65/155 (41%), Gaps = 10/155 (6%)
Query: 184 EAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVH 243
EAE A L+ + AA + ++ + QL+ ++ E + LE
Sbjct: 1359 EAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQE---EEAGALEAGEEARRRAA 1415
Query: 244 THKTELNQTIQELEETLKLKEEEIERLKQEIDNA-RELQEQRDSLT------QKLQEVEI 296
L Q + E ET+ E RL+QE+D+A +L++QR ++ +K ++
Sbjct: 1416 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1475
Query: 297 RNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLE 331
K + + +R E E+EA +L LE
Sbjct: 1476 EEKAAVLRAVEERERAEAEGREREARALSLTRALE 1510
Score = 32.3 bits (72), Expect = 0.66
Identities = 49/250 (19%), Positives = 101/250 (40%), Gaps = 31/250 (12%)
Query: 107 KEAARLAKEKSQEKMELTSTPSQESAGGD-LQSPLTPESINGTDDERTPDVTQNSEPRAE 165
+ AAR A+ +Q E T T + G LQ L ++ D E+ + E +
Sbjct: 1412 RRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATM---DLEQQRQLVSTLEKKQR 1468
Query: 166 PTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERL 225
L ++ + E E A +G + A L A +EE E
Sbjct: 1469 KFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTR------------ALEEEQEAR 1516
Query: 226 HKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEE-------EIERLKQEIDNAR 278
+ + + ++ A+ + K ++ +++ ELE ++ E+ ++ L+ E+ A
Sbjct: 1517 EELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAE 1576
Query: 279 ELQEQRDSLTQKLQ---EVEIRNKDLEG-----QLSDLEQRLEKSQNEQEAFRNNLKTLL 330
+ + + + Q L+ E +++ +D G QL+ + E ++E+ R
Sbjct: 1577 DAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAAR 1636
Query: 331 EILDGKIFEL 340
+ L+G++ EL
Sbjct: 1637 KKLEGELEEL 1646
Score = 29.3 bits (64), Expect = 5.6
Identities = 24/92 (26%), Positives = 43/92 (46%), Gaps = 5/92 (5%)
Query: 196 KLTAALLESTANVKQWKQQLAAYQEEAERL----HKRVTELECVSSQANAVHTHKTELNQ 251
+L L + VKQ K+QL +EEA R + ELE V+ A +++ T L
Sbjct: 1884 QLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRN 1943
Query: 252 TIQELEETLKLKE-EEIERLKQEIDNARELQE 282
++ T + ++ RL++ + + E +E
Sbjct: 1944 RLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 1975
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 55.1 bits (131), Expect = 1e-07
Identities = 60/263 (22%), Positives = 120/263 (45%), Gaps = 27/263 (10%)
Query: 105 EFKEAARLAKEKSQE-KMELTSTPSQESAGGD--LQSPLTPESINGTDDERTPDVTQNSE 161
E + A R+A++ + + + ++T + +A D L+ +T +++ T ER D+ E
Sbjct: 1587 ELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALK-TQHER--DLQGRDE 1643
Query: 162 PRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAY--- 218
E + + + + E + TL AA + +++ K Q+A+
Sbjct: 1644 AGEERRRQLAKQLRDAEVERDEERKQRTLA------VAARKKLEGELEELKAQMASAGQG 1697
Query: 219 -QEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEI--- 274
+E ++L K +++ + + T + E+ +E E+ LK E E+ RL++E+
Sbjct: 1698 KEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAAS 1757
Query: 275 DNAR-ELQEQRDSLTQKLQEVEI-------RNKDLEGQLSDLEQRLEKSQNEQEAFRNNL 326
D AR + Q+ RD + ++ + + LEG+L LE+ LE+ Q+ E +
Sbjct: 1758 DRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRY 1817
Query: 327 KTLLEILDGKIFELTELRDNLAK 349
+ LL ++ EL+ R AK
Sbjct: 1818 RKLLLQVESLTTELSAERSFSAK 1840
Score = 44.3 bits (103), Expect = 2e-04
Identities = 59/225 (26%), Positives = 86/225 (38%), Gaps = 53/225 (23%)
Query: 161 EPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQE 220
+ RA+ Q SA E+ L+G A+L ++ + A +E
Sbjct: 913 QARAQELQKVQELQQQSA------REVGELQGRVAQLEEERARLAEQLRAEAELCAEAEE 966
Query: 221 EAERLHKRVTELECVSSQANA-----------VHTHKTELNQTIQELEETLKLKEEEIER 269
RL R ELE V S+ A + T K L Q IQELE L+ +E ++
Sbjct: 967 TRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQK 1026
Query: 270 LKQE------------------IDNARELQEQRDSLTQKLQE-----------VEIRNK- 299
L+ E D +L ++R L +L E V+ NK
Sbjct: 1027 LQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKL 1086
Query: 300 --DLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTE 342
E ++D+E RL K +E R L+ L LDG+ EL E
Sbjct: 1087 RLKYEATIADMEDRLRK----EEKGRQELEKLKRRLDGESSELQE 1127
Score = 40.0 bits (92), Expect = 0.003
Identities = 41/178 (23%), Positives = 79/178 (44%), Gaps = 17/178 (9%)
Query: 175 HSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELEC 234
H + H EAE +G KL + + A +K++++ L +++ +L K LE
Sbjct: 1009 HIQELEAHLEAE----EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLED 1064
Query: 235 VSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEV 294
++ ++ Q EE K+K RLK E A +++++ + QE+
Sbjct: 1065 RLAEFSS------------QAAEEEEKVKSLNKLRLKYEATIA-DMEDRLRKEEKGRQEL 1111
Query: 295 EIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLE 352
E + L+G+ S+L++++ + Q E R L E L + + A+LL+
Sbjct: 1112 EKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLK 1169
Score = 38.5 bits (88), Expect = 0.009
Identities = 31/121 (25%), Positives = 58/121 (47%), Gaps = 16/121 (13%)
Query: 224 RLHKRVTELECVSSQANAVHTHKTELNQTIQELEE------------TLKLKEEEI---E 268
RL +V L V+ Q + EL Q +QEL++ +L+EE E
Sbjct: 894 RLFTKVKPLLQVTRQDEVLQARAQEL-QKVQELQQQSAREVGELQGRVAQLEEERARLAE 952
Query: 269 RLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKT 328
+L+ E + E +E R L + QE+E+ +LE ++ + E+ + Q E++ + +++
Sbjct: 953 QLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQE 1012
Query: 329 L 329
L
Sbjct: 1013 L 1013
Score = 37.7 bits (86), Expect = 0.016
Identities = 60/250 (24%), Positives = 99/250 (39%), Gaps = 24/250 (9%)
Query: 96 LSKFAEKFQEFK------EAARLAKEK--SQEKMELTS--TPSQESAGGDLQSPLTPESI 145
L + AE+ ++ + E RLA E S+ + EL+S T QE + L + +
Sbjct: 1263 LGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEV 1322
Query: 146 NGT--DDERT----PDVTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTA 199
G D ER + Q ++ E AL + S I EL++ +
Sbjct: 1323 QGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTI--RLSKELSSTEAQLHDAQE 1380
Query: 200 ALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEET 259
L E T ++ A + EA L +++ E +A EL +L E
Sbjct: 1381 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGR------ELQTAQAQLSEW 1434
Query: 260 LKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQ 319
+ +EEE L+ + R + ++LTQ+L E LE L+Q L+ + +
Sbjct: 1435 RRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL 1494
Query: 320 EAFRNNLKTL 329
E R + TL
Sbjct: 1495 EQQRQLVSTL 1504
Score = 35.8 bits (81), Expect = 0.060
Identities = 40/158 (25%), Positives = 67/158 (42%), Gaps = 12/158 (7%)
Query: 203 ESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQEL----EE 258
E A K KQ+ ++ E L ELE NA +++ Q + EL EE
Sbjct: 1188 ERVARTKAEKQR----RDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1243
Query: 259 TLKLKEEEIERLKQEIDNA-RELQEQRDSLTQKLQEVEIRNKDLEGQLSDLE---QRLEK 314
++ E ++ L+Q A EL EQ + + E LE ++S+L L+
Sbjct: 1244 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1303
Query: 315 SQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLE 352
++ E E R L+ L+ + G+ + R A+ L+
Sbjct: 1304 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1341
Score = 33.5 bits (75), Expect = 0.30
Identities = 35/173 (20%), Positives = 71/173 (41%), Gaps = 23/173 (13%)
Query: 186 ELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKR-VTELECVSSQANAVHT 244
EL+ + +AK + + +++ + +L A HK + LE +QA
Sbjct: 1830 ELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLE 1889
Query: 245 HKTE--------LNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEI 296
+T + + + L+E + EEE + D L +L++ +
Sbjct: 1890 QETRERILSGKLVRRAEKRLKEVVLQVEEE--------------RRVADQLRDQLEKGNL 1935
Query: 297 RNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAK 349
R K L+ QL + E+ ++Q + + L+ + E + E+T LR+ L +
Sbjct: 1936 RVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRR 1988
Score = 33.1 bits (74), Expect = 0.39
Identities = 37/155 (23%), Positives = 65/155 (41%), Gaps = 10/155 (6%)
Query: 184 EAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVH 243
EAE A L+ + AA + ++ + QL+ ++ E + LE
Sbjct: 1400 EAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQE---EEAGALEAGEEARRRAA 1456
Query: 244 THKTELNQTIQELEETLKLKEEEIERLKQEIDNA-RELQEQRDSLT------QKLQEVEI 296
L Q + E ET+ E RL+QE+D+A +L++QR ++ +K ++
Sbjct: 1457 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1516
Query: 297 RNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLE 331
K + + +R E E+EA +L LE
Sbjct: 1517 EEKAAVLRAVEERERAEAEGREREARALSLTRALE 1551
Score = 32.3 bits (72), Expect = 0.66
Identities = 49/250 (19%), Positives = 101/250 (40%), Gaps = 31/250 (12%)
Query: 107 KEAARLAKEKSQEKMELTSTPSQESAGGD-LQSPLTPESINGTDDERTPDVTQNSEPRAE 165
+ AAR A+ +Q E T T + G LQ L ++ D E+ + E +
Sbjct: 1453 RRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATM---DLEQQRQLVSTLEKKQR 1509
Query: 166 PTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERL 225
L ++ + E E A +G + A L A +EE E
Sbjct: 1510 KFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTR------------ALEEEQEAR 1557
Query: 226 HKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEE-------EIERLKQEIDNAR 278
+ + + ++ A+ + K ++ +++ ELE ++ E+ ++ L+ E+ A
Sbjct: 1558 EELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAE 1617
Query: 279 ELQEQRDSLTQKLQ---EVEIRNKDLEG-----QLSDLEQRLEKSQNEQEAFRNNLKTLL 330
+ + + + Q L+ E +++ +D G QL+ + E ++E+ R
Sbjct: 1618 DAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAAR 1677
Query: 331 EILDGKIFEL 340
+ L+G++ EL
Sbjct: 1678 KKLEGELEEL 1687
Score = 29.3 bits (64), Expect = 5.6
Identities = 24/92 (26%), Positives = 43/92 (46%), Gaps = 5/92 (5%)
Query: 196 KLTAALLESTANVKQWKQQLAAYQEEAERL----HKRVTELECVSSQANAVHTHKTELNQ 251
+L L + VKQ K+QL +EEA R + ELE V+ A +++ T L
Sbjct: 1925 QLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRN 1984
Query: 252 TIQELEETLKLKE-EEIERLKQEIDNARELQE 282
++ T + ++ RL++ + + E +E
Sbjct: 1985 RLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 2016
>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
Length = 1219
Score = 54.7 bits (130), Expect = 1e-07
Identities = 48/212 (22%), Positives = 97/212 (45%), Gaps = 22/212 (10%)
Query: 111 RLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRAEPTQNA 170
R+ +E + K E+ ++ D S L ER + S E N+
Sbjct: 569 RIIQENERLKQEILEKSNRIEEQNDKISELI---------ERNQRYVEQSNLMMEKRNNS 619
Query: 171 LPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVT 230
L +++ +A + + AK+T L +TA V + ++ A+Q++ L ++T
Sbjct: 620 L-----QTATENTQARVLHAEQEKAKVTEELAAATAQVSHLQLKMTAHQKKETELQMQLT 674
Query: 231 ELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQK 290
E + + + T++ + EL+ET E+ + K E N ++L+ + SL ++
Sbjct: 675 E---SLKETDLLRGQLTKVQAKLSELQET---SEQAQSKFKSEKQNRKQLELKVTSLEEE 728
Query: 291 LQEVEIRNKDLEGQLSDLEQR--LEKSQNEQE 320
L ++ + + LE LS+ +++ E+SQ E+E
Sbjct: 729 LTDLRVEKESLEKNLSERKKKSAQERSQAEEE 760
Score = 40.0 bits (92), Expect = 0.003
Identities = 59/263 (22%), Positives = 116/263 (44%), Gaps = 43/263 (16%)
Query: 101 EKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNS 160
EK + +E A + S ++++T+ +E+ +LQ LT ES+ TD
Sbjct: 637 EKAKVTEELAAATAQVSHLQLKMTAHQKKET---ELQMQLT-ESLKETD----------- 681
Query: 161 EPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQE 220
R + T+ S S+ +++ + K N +L V +++L +
Sbjct: 682 LLRGQLTKVQAKLSELQETSEQAQSKFKSEKQNRKQLEL-------KVTSLEEELTDLRV 734
Query: 221 EAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNAREL 280
E E L K ++E + S+Q E +Q +E++E K +EE+++L+Q + R
Sbjct: 735 EKESLEKNLSERKKKSAQ---------ERSQAEEEIDEIRKSYQEELDKLRQLLKKTRVS 785
Query: 281 QEQRDSLTQKLQEVEIRNKDLEGQLSDL-----EQRLEKSQN---EQEAFRNNLKTLLE- 331
+Q + L + E++ + E + L ++ L++ Q +++A++ L L E
Sbjct: 786 TDQAAAEQLSLVQAELQTQ-WEAKCEHLLASAKDEHLQQYQEVCAQRDAYQQKLVQLQEK 844
Query: 332 --ILDGKIFELTELRDNLAKLLE 352
L +I LT+ + K LE
Sbjct: 845 CLALQAQITALTKQNEQHIKELE 867
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 53.5 bits (127), Expect = 3e-07
Identities = 45/187 (24%), Positives = 82/187 (43%), Gaps = 18/187 (9%)
Query: 181 KHWEAELATLKGNNAKLTAA------LLESTANVKQWKQQLAAYQEE---------AERL 225
+H E E+ K ++K A +L+ N K K + A E A
Sbjct: 738 QHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLK 797
Query: 226 HKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRD 285
HK E + + + LN + Q+L+++L+ K++ IE L++ + + ++ +R+
Sbjct: 798 HKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAERE 857
Query: 286 SLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRD 345
+ L + E + E Q+ +L +EK + E E+ + L + + L K LT LR
Sbjct: 858 MV---LAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRA 914
Query: 346 NLAKLLE 352
K LE
Sbjct: 915 ERRKHLE 921
Score = 52.8 bits (125), Expect = 5e-07
Identities = 55/261 (21%), Positives = 111/261 (42%), Gaps = 30/261 (11%)
Query: 101 EKFQEFKEAARLAKEKSQE---KMELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVT 157
E + F+ A AK K+ + +M+ + S E DL+ + NG
Sbjct: 363 EMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGA--------L 414
Query: 158 QNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAA 217
E E Q + SHS +K +L L A ++ K++ A
Sbjct: 415 STEEREEEMKQMEVYRSHSKF-----------MKNKVEQLKEELSSKEAQWEELKKKAAG 463
Query: 218 YQEEA----ERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQE 273
Q E + L ++ TEL + ++ + ++ Q I+ L+E+L KE+ L+ E
Sbjct: 464 LQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTE 523
Query: 274 IDNARELQEQRDSL----TQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTL 329
+D R E+++++ T+++Q++ G++ DL+ L+ + + + ++ L
Sbjct: 524 VDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENL 583
Query: 330 LEILDGKIFELTELRDNLAKL 350
E L K +++ L++ + L
Sbjct: 584 QEQLRDKEKQMSSLKERVKSL 604
Score = 47.8 bits (112), Expect = 2e-05
Identities = 69/280 (24%), Positives = 124/280 (44%), Gaps = 26/280 (9%)
Query: 97 SKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDERTPDV 156
SK A+ + K+AA L E Q K EL+ ++ A LQ+ L + +D ++ +V
Sbjct: 449 SKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLA---LQTKLETLTNQFSDSKQHIEV 505
Query: 157 TQNS----EPRAEPTQNALPF------SHSSAISKHWEA--ELATLKGNNAKLTAALLES 204
+ S E RA Q + + ++K + ++A KG A L +
Sbjct: 506 LKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDL-KD 564
Query: 205 TANVKQWKQQLAAYQEE--AERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKL 262
+VK+ K + + E E+L + ++ + + ++ T + + LEE L
Sbjct: 565 MLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAE 624
Query: 263 KEEEIERLKQEID-NARELQEQRDSLTQKLQEVEIRNKDLEGQL-------SDLEQRLEK 314
KE IERLK++ D + RE QE+ D+ + L++++ + L+G L DL++
Sbjct: 625 KERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASS 684
Query: 315 SQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLECS 354
+ + LKTL L+ K E ++ L K E +
Sbjct: 685 LASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAA 724
Score = 43.1 bits (100), Expect = 4e-04
Identities = 66/323 (20%), Positives = 130/323 (40%), Gaps = 44/323 (13%)
Query: 63 PNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKME 122
P+ TK Q + DS+ + S E L E+ Q K L+ E+ +E+M+
Sbjct: 372 PDSAKTKALQTVIEMKDSKIS-------SMERGLRDLEEEIQMLKSNGALSTEEREEEMK 424
Query: 123 LTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRAEPTQNALPFSHSSAISKH 182
S + E ++ + + + + +AE Q S
Sbjct: 425 QMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLA 484
Query: 183 WEAELATLKG--NNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECV----- 235
+ +L TL +++K +L+ + K+ Q+ A Q E + L R+ E E +
Sbjct: 485 LQTKLETLTNQFSDSKQHIEVLKESLTAKE--QRAAILQTEVDALRLRLEEKETMLNKKT 542
Query: 236 ----------SSQANAVHTHKTELN----------QTIQELEETLKLKEEEIERLKQEID 275
+QA +H K L+ + I+ L+E L+ KE+++ LK+ +
Sbjct: 543 KQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVK 602
Query: 276 NARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQ-EAFRNNLKTLLE--- 331
+ + D+ L+E + +L + R E+ + E+ + ++ +LK L E
Sbjct: 603 SLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVS 662
Query: 332 ILDGKIFE----LTELRDNLAKL 350
+L G + E L +L+++ + L
Sbjct: 663 LLQGDLSEKEASLLDLKEHASSL 685
Score = 37.4 bits (85), Expect = 0.021
Identities = 45/231 (19%), Positives = 92/231 (39%), Gaps = 21/231 (9%)
Query: 101 EKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDD-----ERTPD 155
EK + K+ A L ++ + ++ + +E + + E+ D+ ++ D
Sbjct: 771 EKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQD 830
Query: 156 VTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQL 215
+ + R E + AL ++ E E+ + +A+ A KQ ++ L
Sbjct: 831 SLRKKDDRIEELEEAL----RESVQITAEREMVLAQEESARTNAE--------KQVEELL 878
Query: 216 AAYQEEAERLHKRVTELECVSSQANAVHTHKTELN-QTIQELEETLKLKEEEIERLKQEI 274
A ++ + L +L TH T L + + LEE L++K+E + E
Sbjct: 879 MAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEK 938
Query: 275 DNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNN 325
D L E S + +EV ++ + + L+Q ++QN + +N
Sbjct: 939 DANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQ---QTQNRMKLMADN 986
Score = 35.0 bits (79), Expect = 0.10
Identities = 37/163 (22%), Positives = 72/163 (44%), Gaps = 24/163 (14%)
Query: 174 SHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELE 233
S ++I W EL K A + + + WK+Q QEE + + + L+
Sbjct: 181 SSMNSIKTFWSPELK-------KERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQ 233
Query: 234 CVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQE 293
+ + + +LNQ Q+ + + + E + L +E N + L + + ++ +E
Sbjct: 234 ------DELRIQR-DLNQLFQQ-DSSSRTGEPCVAELTEE--NFQRLHAEHE---RQAKE 280
Query: 294 VEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGK 336
+ + K LE ++E R+E + A ++K LLE+L K
Sbjct: 281 LFLLRKTLE----EMELRIETQKQTLNARDESIKKLLEMLQSK 319
Score = 31.2 bits (69), Expect = 1.5
Identities = 35/139 (25%), Positives = 57/139 (41%), Gaps = 8/139 (5%)
Query: 196 KLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANA-VHTHKTELNQTIQ 254
+L AL ES + + LA + K+V EL + + + K +L+ T Q
Sbjct: 841 ELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQ 900
Query: 255 ELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEK 314
L E KE + L+ E R+ E+ + Q+ I KD L +L +K
Sbjct: 901 SLAE----KETHLTNLRAE---RRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKK 953
Query: 315 SQNEQEAFRNNLKTLLEIL 333
+Q E A + L++ L
Sbjct: 954 TQEEVAALKREKDRLVQQL 972
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 53.5 bits (127), Expect = 3e-07
Identities = 45/187 (24%), Positives = 82/187 (43%), Gaps = 18/187 (9%)
Query: 181 KHWEAELATLKGNNAKLTAA------LLESTANVKQWKQQLAAYQEE---------AERL 225
+H E E+ K ++K A +L+ N K K + A E A
Sbjct: 710 QHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLK 769
Query: 226 HKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRD 285
HK E + + + LN + Q+L+++L+ K++ IE L++ + + ++ +R+
Sbjct: 770 HKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAERE 829
Query: 286 SLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRD 345
+ L + E + E Q+ +L +EK + E E+ + L + + L K LT LR
Sbjct: 830 MV---LAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRA 886
Query: 346 NLAKLLE 352
K LE
Sbjct: 887 ERRKHLE 893
Score = 50.8 bits (120), Expect = 2e-06
Identities = 36/175 (20%), Positives = 83/175 (47%), Gaps = 8/175 (4%)
Query: 184 EAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEA----ERLHKRVTELECVSSQA 239
E E+ LK N A T E ++ ++ + + + L ++ TEL + ++
Sbjct: 402 EEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKL 461
Query: 240 NAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSL----TQKLQEVE 295
+ ++ Q I+ L+E+L KE+ L+ E+D R E+++++ T+++Q++
Sbjct: 462 ETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMA 521
Query: 296 IRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKL 350
G++ DL+ L+ + + + ++ L E L K +++ L++ + L
Sbjct: 522 EEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSL 576
Score = 46.2 bits (108), Expect = 4e-05
Identities = 41/163 (25%), Positives = 76/163 (46%), Gaps = 10/163 (6%)
Query: 202 LESTANVKQWKQQLAAYQEE--AERLHKRVTELECVSSQANAVHTHKTELNQTIQELEET 259
L+ +VK+ K + + E E+L + ++ + + ++ T + + LEE
Sbjct: 534 LKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEA 593
Query: 260 LKLKEEEIERLKQEID-NARELQEQRDSLTQKLQEVEIRNKDLEGQL-------SDLEQR 311
L KE IERLK++ D + RE QE+ D+ + L++++ + L+G L DL++
Sbjct: 594 LAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEH 653
Query: 312 LEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLECS 354
+ + LKTL L+ K E ++ L K E +
Sbjct: 654 ASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAA 696
Score = 43.1 bits (100), Expect = 4e-04
Identities = 62/295 (21%), Positives = 119/295 (40%), Gaps = 45/295 (15%)
Query: 101 EKFQEFKEAARLAKEKSQE---KMELTSTPSQESAGGDLQSPLTPESING--TDDERTPD 155
E + F+ A AK K+ + +M+ + S E DL+ + NG + +ER +
Sbjct: 363 EMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEE 422
Query: 156 VTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQL 215
+ Q R+ + EL L+ LT +S +++ K+ L
Sbjct: 423 MKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESL 482
Query: 216 AA-------YQEEAERLHKRVTELECV---------------SSQANAVHTHKTELN--- 250
A Q E + L R+ E E + +QA +H K L+
Sbjct: 483 TAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKE 542
Query: 251 -------QTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEG 303
+ I+ L+E L+ KE+++ LK+ + + + D+ L+E +
Sbjct: 543 RKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIE 602
Query: 304 QLSDLEQRLEKSQNEQ-EAFRNNLKTLLE---ILDGKIFE----LTELRDNLAKL 350
+L + R E+ + E+ + ++ +LK L E +L G + E L +L+++ + L
Sbjct: 603 RLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSL 657
Score = 37.4 bits (85), Expect = 0.021
Identities = 45/231 (19%), Positives = 92/231 (39%), Gaps = 21/231 (9%)
Query: 101 EKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDD-----ERTPD 155
EK + K+ A L ++ + ++ + +E + + E+ D+ ++ D
Sbjct: 743 EKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQD 802
Query: 156 VTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQL 215
+ + R E + AL ++ E E+ + +A+ A KQ ++ L
Sbjct: 803 SLRKKDDRIEELEEAL----RESVQITAEREMVLAQEESARTNAE--------KQVEELL 850
Query: 216 AAYQEEAERLHKRVTELECVSSQANAVHTHKTELN-QTIQELEETLKLKEEEIERLKQEI 274
A ++ + L +L TH T L + + LEE L++K+E + E
Sbjct: 851 MAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEK 910
Query: 275 DNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNN 325
D L E S + +EV ++ + + L+Q ++QN + +N
Sbjct: 911 DANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQ---QTQNRMKLMADN 958
Score = 35.0 bits (79), Expect = 0.10
Identities = 37/163 (22%), Positives = 72/163 (44%), Gaps = 24/163 (14%)
Query: 174 SHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELE 233
S ++I W EL K A + + + WK+Q QEE + + + L+
Sbjct: 181 SSMNSIKTFWSPELK-------KERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQ 233
Query: 234 CVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQE 293
+ + + +LNQ Q+ + + + E + L +E N + L + + ++ +E
Sbjct: 234 ------DELRIQR-DLNQLFQQ-DSSSRTGEPCVAELTEE--NFQRLHAEHE---RQAKE 280
Query: 294 VEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGK 336
+ + K LE ++E R+E + A ++K LLE+L K
Sbjct: 281 LFLLRKTLE----EMELRIETQKQTLNARDESIKKLLEMLQSK 319
Score = 31.2 bits (69), Expect = 1.5
Identities = 35/139 (25%), Positives = 57/139 (41%), Gaps = 8/139 (5%)
Query: 196 KLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANA-VHTHKTELNQTIQ 254
+L AL ES + + LA + K+V EL + + + K +L+ T Q
Sbjct: 813 ELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQ 872
Query: 255 ELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEK 314
L E KE + L+ E R+ E+ + Q+ I KD L +L +K
Sbjct: 873 SLAE----KETHLTNLRAE---RRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKK 925
Query: 315 SQNEQEAFRNNLKTLLEIL 333
+Q E A + L++ L
Sbjct: 926 TQEEVAALKREKDRLVQQL 944
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 53.5 bits (127), Expect = 3e-07
Identities = 54/249 (21%), Positives = 108/249 (43%), Gaps = 14/249 (5%)
Query: 107 KEAARLAKEKSQEKMELTSTPSQESAG-----GDLQSPLTPESINGTDDERTPDVTQNSE 161
+E + A E+SQE ++L S E A +L + LT D E+ + +
Sbjct: 254 QELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETV 313
Query: 162 PRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEE 221
E L H +++S++ + E +L+ +T ++E N+ Q + + +
Sbjct: 314 EILETNHTEL-MEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELD 372
Query: 222 AERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQ 281
+ + + + V + T Q +Q+L + L +E + L+Q+ D + +
Sbjct: 373 SSIFSQ--FDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHD---QWE 427
Query: 282 EQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAF---RNNLKTLLEILDGKIF 338
E+ +L Q+LQ++ L GQ DL+ ++ E+E R L+ LE+L+ + +
Sbjct: 428 EEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAW 487
Query: 339 ELTELRDNL 347
L + L
Sbjct: 488 RLRRVNVEL 496
Score = 52.8 bits (125), Expect = 5e-07
Identities = 64/265 (24%), Positives = 111/265 (41%), Gaps = 37/265 (13%)
Query: 91 SSEHHLSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQES-AGGDLQSPLTPESINGTD 149
S+ H L + K Q+ ++ R +K +E+ LT T +++S +LQ D
Sbjct: 1243 SALHKLHQDLWKTQQTRDVLRDQVQKLEER--LTDTEAEKSQVHTELQ-----------D 1289
Query: 150 DERTPDVTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVK 209
+R Q + + E QN+L E+EL L A L + L +
Sbjct: 1290 LQRQLSQNQEEKSKWEGKQNSL------------ESELMELHETMASLQSRLRRAELQRM 1337
Query: 210 QWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIER 269
+ + + Q E L +V L+ +A A + L + ++ LKLK EE+E
Sbjct: 1338 EAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVES 1397
Query: 270 LKQ-----------EIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNE 318
++ ++ + LQE LTQ L E E + L GQ+ +LE++ E +
Sbjct: 1398 ERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAA 1457
Query: 319 QEAFRNNLKTLLEILDGKIFELTEL 343
E +LK + +D + ++ EL
Sbjct: 1458 LELLSLDLKKRNQEVDLQQEQIQEL 1482
Score = 52.0 bits (123), Expect = 8e-07
Identities = 41/164 (25%), Positives = 80/164 (48%), Gaps = 36/164 (21%)
Query: 225 LHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQR 284
L +R EL+ SSQ + + +H T L + +QE ++ +K + E+IE L+++ ++ + E+R
Sbjct: 1597 LEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERR 1656
Query: 285 DS----------------------LTQKLQEVEI----RNKDLEGQLSDLEQRLEKSQNE 318
D L + L+++++ R ++L Q +++R E+ +
Sbjct: 1657 DQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGP 1716
Query: 319 QEAFRNNLKTLLEILDGK----------IFELTELRDNLAKLLE 352
+A R +L+ + IL K I EL EL+D L + L+
Sbjct: 1717 SKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQ 1760
Score = 44.7 bits (104), Expect = 1e-04
Identities = 66/277 (23%), Positives = 114/277 (41%), Gaps = 30/277 (10%)
Query: 93 EHHLSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDER 152
+ L+K E + K + ++ Q +ME +E +S L + T+ ER
Sbjct: 870 QQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERT-QAESALCQMQLE-TEKER 927
Query: 153 TP---DVTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVK 209
+ Q + A+ +Q + K E E + +L A E +
Sbjct: 928 VSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGIL--QTQLQEAQRELKEAAR 985
Query: 210 QWKQQLAAYQEEAERLHKRVTEL----ECVSSQANAVHTHKTELNQTIQELEETLKLKE- 264
Q + LAA QEE+ L + +L E + SQ A + + Q +QE KL+E
Sbjct: 986 QHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQE-----KLRET 1040
Query: 265 EEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEG-------QLSDLEQRLEKSQN 317
+E R++ +EL+ ++ SLT L E E R L+ +LS L Q ++++Q
Sbjct: 1041 QEYNRIQ------KELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQG 1094
Query: 318 EQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLECS 354
EQ+ ++ L + + K + L + LE S
Sbjct: 1095 EQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEAS 1131
Score = 44.7 bits (104), Expect = 1e-04
Identities = 55/278 (19%), Positives = 110/278 (39%), Gaps = 40/278 (14%)
Query: 93 EHHLSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDER 152
E H + A + QE + + +E+ +E +Q+ D + L E I +D+R
Sbjct: 1615 ESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQR 1674
Query: 153 T-------PDVTQ-----NSEPRAEPTQNALPFSHSSAISKHWEAELATLKG------NN 194
T D+ Q R TQ L + +A+ +L+ +
Sbjct: 1675 TRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDK 1734
Query: 195 AKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAV------------ 242
K E +++ K QL +++ + LH++V E + SQ
Sbjct: 1735 EKEVECQQEHIHELQELKDQL---EQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAR 1791
Query: 243 ---HTHKTELNQTIQELEETLKLKEEEIERLKQEIDNAR----ELQEQRDSLTQKLQEVE 295
+ L + E + L +++E+E L+QE A+ ++E+ D+L L++
Sbjct: 1792 EQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAH 1851
Query: 296 IRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEIL 333
+ K+ G+L D +++ + + E ++ L E+L
Sbjct: 1852 MTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVL 1889
Score = 41.6 bits (96), Expect = 0.001
Identities = 49/193 (25%), Positives = 82/193 (42%), Gaps = 21/193 (10%)
Query: 164 AEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAE 223
AE +NAL + A E L N L A L ++ + + L QEE E
Sbjct: 636 AEQARNALQVDLAEA-----EKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKE 690
Query: 224 RLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQ 283
+ K+++E Q A T +L+Q + EE L +E E L +E
Sbjct: 691 EIQKKLSESR---HQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVRE---------- 737
Query: 284 RDSLTQKLQEVEIRNKDLEGQ---LSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFEL 340
+ +L +LQ VE +DL Q LS ++ LE S E + + ++ L+ +I +
Sbjct: 738 KAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTV 797
Query: 341 TELRDNLAKLLEC 353
T+ ++ + + C
Sbjct: 798 TQAKEVIQGEVRC 810
Score = 40.0 bits (92), Expect = 0.003
Identities = 49/260 (18%), Positives = 103/260 (39%), Gaps = 25/260 (9%)
Query: 93 EHHLSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDER 152
E + ++ QE +E L ++ Q +++ E+ Q E++ + ++
Sbjct: 1777 EQEIVVLQQQLQEAREQGELKEQSLQSQLD-------EAQRALAQRDQELEALQ-QEQQQ 1828
Query: 153 TPDVTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVKQWK 212
+ + +A+ Q AL +H + +H EL K +L L V+ +
Sbjct: 1829 AQGQEERVKEKADALQGALEQAHMTLKERH--GELQDHKEQARRLEEELAVEGRRVQALE 1886
Query: 213 QQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTE-LNQTIQELEETLKLKEEEIERLK 271
+ L + E+ K + L+ ++ H +T L + + + LK +++E+E L+
Sbjct: 1887 EVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALR 1946
Query: 272 QEIDNARELQEQRDSLTQKLQEV--------------EIRNKDLEGQLSDLEQRLEKSQN 317
E ++R +E + + LQE + +L L L+ S +
Sbjct: 1947 AESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLD 2006
Query: 318 EQEAFRNNLKTLLEILDGKI 337
+A L+ L I +G+I
Sbjct: 2007 ACQAHSRQLEEALRIQEGEI 2026
Score = 38.9 bits (89), Expect = 0.007
Identities = 38/152 (25%), Positives = 72/152 (47%), Gaps = 17/152 (11%)
Query: 213 QQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQ-TIQELE---ETLKLK----- 263
Q + + + + + L K++ LEC++ + H HK E Q I+ELE ET ++
Sbjct: 1536 QMIESQRGQVQDLKKQLVTLECLALELEENH-HKMECQQKLIKELEGQRETQRVALTHLT 1594
Query: 264 ---EEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQE 320
EE + L+ + +L+ L ++LQE + K Q+ +L++ +K Q+
Sbjct: 1595 LDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQR--QKEHLTQD 1652
Query: 321 AFRNNLKTLLEILDGKIFELTELRDNLAKLLE 352
R + + +L+ +I L + R K+LE
Sbjct: 1653 LERRDQELMLQ--KERIQVLEDQRTRQTKILE 1682
Score = 38.1 bits (87), Expect = 0.012
Identities = 51/205 (24%), Positives = 89/205 (43%), Gaps = 48/205 (23%)
Query: 163 RAEPTQNALPFSHSSAISKHW----EAELA-TLKGNNAKLTAALLESTANVKQWKQQLAA 217
RAE Q AL +H++ K +AEL+ +L+ + A L A+L A+ +Q ++ L
Sbjct: 1962 RAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRI 2021
Query: 218 -----------YQEEAERL------------HKRVTELECVSSQANAVHTHKTE------ 248
YQE+ ++L H++ E S A V + +
Sbjct: 2022 QEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLG 2081
Query: 249 ----------LNQTIQELEETLKLKEEEIERLK--QEIDNARELQEQRDSLTQKLQEVEI 296
L+Q+++EL+ TL KE+EI L+ Q+ +N L T ++E +
Sbjct: 2082 QEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHK--TSPMEEQSL 2139
Query: 297 RNKDLEGQLSDLEQRLEKSQNEQEA 321
+ LE +L +RL+ + + EA
Sbjct: 2140 KLDSLEPRLQRELERLQAALRQTEA 2164
Score = 37.7 bits (86), Expect = 0.016
Identities = 66/281 (23%), Positives = 113/281 (40%), Gaps = 49/281 (17%)
Query: 89 GFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKMEL-TSTPSQESAGGDLQSPLTPESING 147
G SS L + + F+ ++ + + K Q ++++ T T ++E G+++
Sbjct: 761 GLSSAKELLE-SSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTER 819
Query: 148 TDDERTPDVTQNSEPRAEPT-------QNALPFSHSSAISKHWEAELATLKGNNAKLTAA 200
+ E+ D +AE Q A + + + WE E + + AK +
Sbjct: 820 SQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALES 879
Query: 201 L----LESTANVKQWKQQLAAYQEEAERLHKRV----------TELECVSSQANAVHTHK 246
L +E +K+ + ++ A Q + E + TE E VS + T K
Sbjct: 880 LEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQK 939
Query: 247 TELNQTIQELE------ETLKLKEEEI----------------ERLKQEIDNARELQEQR 284
EL Q+LE + KLKE+E E +Q D+ LQE+
Sbjct: 940 -ELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEES 998
Query: 285 DSLTQKLQEVEIRNKDLEGQL--SDLEQRLEKSQNEQEAFR 323
SL Q +++ + +DL+ QL D QRL + Q QE R
Sbjct: 999 SSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVE-QEVQEKLR 1038
Score = 37.0 bits (84), Expect = 0.027
Identities = 28/136 (20%), Positives = 66/136 (48%), Gaps = 6/136 (4%)
Query: 212 KQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLK 271
+QQ ++EE + L +R+ +L + + + + +L + L + +L ++ E L+
Sbjct: 420 QQQHDQWEEEGKALRQRLQKL---TGERDTLAGQTVDLQGEVDSLSKERELLQKAREELR 476
Query: 272 QEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLE 331
Q+++ L+++ L + E++++ +GQ + ++ L + E+E + L L
Sbjct: 477 QQLE---VLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEA 533
Query: 332 ILDGKIFELTELRDNL 347
+ EL LR+ L
Sbjct: 534 KQSESLSELITLREAL 549
Score = 36.6 bits (83), Expect = 0.035
Identities = 38/170 (22%), Positives = 72/170 (42%), Gaps = 20/170 (11%)
Query: 184 EAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVH 243
+ EL +G + ALL T LA +EE E L ++ ELE A
Sbjct: 1408 QGELKVAQGKALQENLALLTQT---------LAEREEEVETLRGQIQELEKQREMQKAA- 1457
Query: 244 THKTELNQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEG 303
++ L LK + +E++ +++I + + + L +QE E +
Sbjct: 1458 ---------LELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQRE 1508
Query: 304 QLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLEC 353
Q+ +LE+ E +N E L+ ++++ + ++ +L+ L LEC
Sbjct: 1509 QIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLV-TLEC 1557
Score = 36.2 bits (82), Expect = 0.046
Identities = 49/233 (21%), Positives = 96/233 (41%), Gaps = 25/233 (10%)
Query: 107 KEAARLAKEKSQEKME-----LTSTPSQESAGGDLQSPL-TPESINGTDDERTPDVTQNS 160
+E + AKE ++E + +Q SA G L+ L T S +E + +
Sbjct: 1343 RELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERA 1402
Query: 161 EPRAEPTQNALPFSHSSAISKHW----------EAELATLKGNNAKLT-------AALLE 203
+ E Q L + A+ ++ E E+ TL+G +L AAL
Sbjct: 1403 QALQE--QGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALEL 1460
Query: 204 STANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLK 263
+ ++K+ Q++ QE+ + L K + LE + T + I+ELE+ + +
Sbjct: 1461 LSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQ 1520
Query: 264 EEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQ 316
+E E++ ++ E + Q L++ + + L +L + ++E Q
Sbjct: 1521 RNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQ 1573
Score = 35.0 bits (79), Expect = 0.10
Identities = 26/113 (23%), Positives = 56/113 (49%), Gaps = 6/113 (5%)
Query: 219 QEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNAR 278
Q A L KR L +S++A A HK L+Q + + ++T + +++++L++ + +
Sbjct: 1220 QNGARSLFKRGPLLTALSAEAVASALHK--LHQDLWKTQQTRDVLRDQVQKLEERLTDTE 1277
Query: 279 ELQEQRDSLTQKLQEVEIRNKD----LEGQLSDLEQRLEKSQNEQEAFRNNLK 327
+ Q + Q LQ +N++ EG+ + LE L + + ++ L+
Sbjct: 1278 AEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLR 1330
Score = 30.8 bits (68), Expect = 1.9
Identities = 43/224 (19%), Positives = 83/224 (37%), Gaps = 35/224 (15%)
Query: 96 LSKFAEKFQEFKEAARLAKEKSQE------KMELTSTPSQESAGGDLQSPLTPESINGTD 149
LSK E Q+ +E R E ++ ++ + +SA G + + +
Sbjct: 461 LSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRE 520
Query: 150 DERTPDVTQNSEPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTAALLESTANVK 209
ER ++ E + + + L + S H E EL L+ ++TAAL + ++
Sbjct: 521 RERLQEMLMGLEAKQSESLSELITLREALESSHLEGEL--LRQEQTEVTAALARAEQSIA 578
Query: 210 QWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIER 269
+ + E L +L ++ A+ K LNQ + +LEE
Sbjct: 579 ELSSSENTLKTEVADLRAAAVKLSALNE---ALALDKVGLNQQLLQLEE----------- 624
Query: 270 LKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLE 313
+ S+ +++ E L+ L++ E+R E
Sbjct: 625 -------------ENQSVCSRMEAAEQARNALQVDLAEAEKRRE 655
Score = 29.6 bits (65), Expect = 4.3
Identities = 29/134 (21%), Positives = 53/134 (39%), Gaps = 7/134 (5%)
Query: 221 EAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNAREL 280
E L + + LE + ++ T+L +++ + K E++E+L + A
Sbjct: 92 EEPNLDELLVRLEEEQQRCESLAEVNTQLRLHMEKADVVNKALREDVEKLTVDWSRA--- 148
Query: 281 QEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFEL 340
RD L +K + ++ + +G L RL E FR + + D + EL
Sbjct: 149 ---RDELMRKESQWQMEQEFFKGYLKGEHGRLLSLWREVVTFRRHFLEMKSATDRDLMEL 205
Query: 341 TELRDNLA-KLLEC 353
L+ LL C
Sbjct: 206 KAEHVRLSGSLLTC 219
>gi|62243374 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 52.8 bits (125), Expect = 5e-07
Identities = 44/163 (26%), Positives = 76/163 (46%), Gaps = 4/163 (2%)
Query: 190 LKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTEL 249
L+ A + E +Q +Q L A ++RL ++ L NA+ +EL
Sbjct: 113 LQEREAGAEEKMQEQLERNRQCQQNLDA---ASKRLREKEDSLAQAGETINALKGRISEL 169
Query: 250 NQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLE 309
++ + E +K E E + L++++D + ++ + Q+LQ + D E Q+ DLE
Sbjct: 170 QWSVMDQEMRVKRLESEKQELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLE 229
Query: 310 QRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLE 352
Q+L Q + A N+K+ L L EL +LR+ A L E
Sbjct: 230 QKL-SLQEQDAAIVKNMKSELVRLPRLERELKQLREESAHLRE 271
Score = 40.4 bits (93), Expect = 0.002
Identities = 38/146 (26%), Positives = 72/146 (49%), Gaps = 15/146 (10%)
Query: 220 EEAERLHKRVTELECVSSQANAVHTHKTE----LNQTIQEL---EETLKLKEEEIERLKQ 272
E + +L +R+ E E VH+H E L+Q ++EL ++ + E E++ LK
Sbjct: 426 EYSPQLTRRMREAE---DMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKS 482
Query: 273 EIDNAREL----QEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKT 328
+ +A + +E+ D+L K++E+E LE + LE +LE+ + + ++ K
Sbjct: 483 QSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQLERRALQGDYDQSRTKV 542
Query: 329 LLEILDGKIFELTELRDNLAKL-LEC 353
L L+ LR++ ++L EC
Sbjct: 543 LHMSLNPTSVARQRLREDHSQLQAEC 568
Score = 38.5 bits (88), Expect = 0.009
Identities = 29/128 (22%), Positives = 56/128 (43%), Gaps = 4/128 (3%)
Query: 213 QQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQ 272
QQ +E AE++ + ++ + +HK + + + + E E++R ++
Sbjct: 46 QQSMQLEERAEQIRSKSHLIQVEREKMQMELSHKRARVELERAASTSARNYEREVDRNQE 105
Query: 273 EIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEI 332
+ R+LQE+ +K+QE RN+ + L +RL E+E +
Sbjct: 106 LLTRIRQLQEREAGAEEKMQEQLERNRQCQQNLDAASKRL----REKEDSLAQAGETINA 161
Query: 333 LDGKIFEL 340
L G+I EL
Sbjct: 162 LKGRISEL 169
Score = 32.3 bits (72), Expect = 0.66
Identities = 57/273 (20%), Positives = 112/273 (41%), Gaps = 34/273 (12%)
Query: 101 EKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNS 160
EK QE E R + Q+ ++ S +E Q+ T ++ G E V +
Sbjct: 122 EKMQEQLERNR----QCQQNLDAASKRLREKEDSLAQAGETINALKGRISELQWSV-MDQ 176
Query: 161 EPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTA-ALLESTANVKQWKQQLAAYQ 219
E R + ++ +H + + A K + + A + +K +Q+L+ +
Sbjct: 177 EMRVKRLESEKQELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLEQKLSLQE 236
Query: 220 EEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARE 279
++A + +EL + + + E + ++E+ ET L +EE+E L++++ +
Sbjct: 237 QDAAIVKNMKSELVRLPRLERELKQLREE-SAHLREMRETNGLLQEELEGLQRKLGRQEK 295
Query: 280 LQE-------QRDSLTQKLQEVE---------IRN-KDLEGQLSDLEQR----------L 312
+QE + + L KLQ E IR +DL + +L+QR +
Sbjct: 296 MQETLVGLELENERLLAKLQSWERLDQTMGLSIRTPEDLSRFVVELQQRELALKDKNSAV 355
Query: 313 EKSQNEQEAFRNNLKTLLEILDGKIFELTELRD 345
S E R L+ L + G++ E + R+
Sbjct: 356 TSSARGLEKARQQLQEELRQVSGQLLEERKKRE 388
Score = 29.3 bits (64), Expect = 5.6
Identities = 20/105 (19%), Positives = 49/105 (46%), Gaps = 3/105 (2%)
Query: 248 ELNQTIQELEETLKLKEEEIERLKQEIDNAR---ELQEQRDSLTQKLQEVEIRNKDLEGQ 304
+L + +++ L + E E+++ E+ + R EL+ + + + RN++L +
Sbjct: 50 QLEERAEQIRSKSHLIQVEREKMQMELSHKRARVELERAASTSARNYEREVDRNQELLTR 109
Query: 305 LSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAK 349
+ L++R ++ + + + + LD L E D+LA+
Sbjct: 110 IRQLQEREAGAEEKMQEQLERNRQCQQNLDAASKRLREKEDSLAQ 154
>gi|62243369 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 52.8 bits (125), Expect = 5e-07
Identities = 44/163 (26%), Positives = 76/163 (46%), Gaps = 4/163 (2%)
Query: 190 LKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTEL 249
L+ A + E +Q +Q L A ++RL ++ L NA+ +EL
Sbjct: 113 LQEREAGAEEKMQEQLERNRQCQQNLDA---ASKRLREKEDSLAQAGETINALKGRISEL 169
Query: 250 NQTIQELEETLKLKEEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLE 309
++ + E +K E E + L++++D + ++ + Q+LQ + D E Q+ DLE
Sbjct: 170 QWSVMDQEMRVKRLESEKQELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLE 229
Query: 310 QRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLE 352
Q+L Q + A N+K+ L L EL +LR+ A L E
Sbjct: 230 QKL-SLQEQDAAIVKNMKSELVRLPRLERELKQLREESAHLRE 271
Score = 40.4 bits (93), Expect = 0.002
Identities = 38/146 (26%), Positives = 72/146 (49%), Gaps = 15/146 (10%)
Query: 220 EEAERLHKRVTELECVSSQANAVHTHKTE----LNQTIQEL---EETLKLKEEEIERLKQ 272
E + +L +R+ E E VH+H E L+Q ++EL ++ + E E++ LK
Sbjct: 426 EYSPQLTRRMREAE---DMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKS 482
Query: 273 EIDNAREL----QEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKT 328
+ +A + +E+ D+L K++E+E LE + LE +LE+ + + ++ K
Sbjct: 483 QSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQLERRALQGDYDQSRTKV 542
Query: 329 LLEILDGKIFELTELRDNLAKL-LEC 353
L L+ LR++ ++L EC
Sbjct: 543 LHMSLNPTSVARQRLREDHSQLQAEC 568
Score = 38.5 bits (88), Expect = 0.009
Identities = 29/128 (22%), Positives = 56/128 (43%), Gaps = 4/128 (3%)
Query: 213 QQLAAYQEEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQ 272
QQ +E AE++ + ++ + +HK + + + + E E++R ++
Sbjct: 46 QQSMQLEERAEQIRSKSHLIQVEREKMQMELSHKRARVELERAASTSARNYEREVDRNQE 105
Query: 273 EIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEI 332
+ R+LQE+ +K+QE RN+ + L +RL E+E +
Sbjct: 106 LLTRIRQLQEREAGAEEKMQEQLERNRQCQQNLDAASKRL----REKEDSLAQAGETINA 161
Query: 333 LDGKIFEL 340
L G+I EL
Sbjct: 162 LKGRISEL 169
Score = 32.3 bits (72), Expect = 0.66
Identities = 57/273 (20%), Positives = 112/273 (41%), Gaps = 34/273 (12%)
Query: 101 EKFQEFKEAARLAKEKSQEKMELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNS 160
EK QE E R + Q+ ++ S +E Q+ T ++ G E V +
Sbjct: 122 EKMQEQLERNR----QCQQNLDAASKRLREKEDSLAQAGETINALKGRISELQWSV-MDQ 176
Query: 161 EPRAEPTQNALPFSHSSAISKHWEAELATLKGNNAKLTA-ALLESTANVKQWKQQLAAYQ 219
E R + ++ +H + + A K + + A + +K +Q+L+ +
Sbjct: 177 EMRVKRLESEKQELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLEQKLSLQE 236
Query: 220 EEAERLHKRVTELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLKQEIDNARE 279
++A + +EL + + + E + ++E+ ET L +EE+E L++++ +
Sbjct: 237 QDAAIVKNMKSELVRLPRLERELKQLREE-SAHLREMRETNGLLQEELEGLQRKLGRQEK 295
Query: 280 LQE-------QRDSLTQKLQEVE---------IRN-KDLEGQLSDLEQR----------L 312
+QE + + L KLQ E IR +DL + +L+QR +
Sbjct: 296 MQETLVGLELENERLLAKLQSWERLDQTMGLSIRTPEDLSRFVVELQQRELALKDKNSAV 355
Query: 313 EKSQNEQEAFRNNLKTLLEILDGKIFELTELRD 345
S E R L+ L + G++ E + R+
Sbjct: 356 TSSARGLEKARQQLQEELRQVSGQLLEERKKRE 388
Score = 29.3 bits (64), Expect = 5.6
Identities = 20/105 (19%), Positives = 49/105 (46%), Gaps = 3/105 (2%)
Query: 248 ELNQTIQELEETLKLKEEEIERLKQEIDNAR---ELQEQRDSLTQKLQEVEIRNKDLEGQ 304
+L + +++ L + E E+++ E+ + R EL+ + + + RN++L +
Sbjct: 50 QLEERAEQIRSKSHLIQVEREKMQMELSHKRARVELERAASTSARNYEREVDRNQELLTR 109
Query: 305 LSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAK 349
+ L++R ++ + + + + LD L E D+LA+
Sbjct: 110 IRQLQEREAGAEEKMQEQLERNRQCQQNLDAASKRLREKEDSLAQ 154
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.123 0.335
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,336,359
Number of Sequences: 37866
Number of extensions: 540803
Number of successful extensions: 11065
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 453
Number of HSP's successfully gapped in prelim test: 1005
Number of HSP's that attempted gapping in prelim test: 4303
Number of HSP's gapped (non-prelim): 5022
length of query: 354
length of database: 18,247,518
effective HSP length: 103
effective length of query: 251
effective length of database: 14,347,320
effective search space: 3601177320
effective search space used: 3601177320
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.