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Search of human proteins with 4758426
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758426 guanine deaminase [Homo sapiens]
(454 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758426 guanine deaminase [Homo sapiens] 913 0.0
gi|223972677 amidohydrolase domain containing 1 [Homo sapiens] 37 0.048
gi|197313748 SET domain containing 2 [Homo sapiens] 36 0.063
gi|226246537 zinc finger protein 407 isoform 3 [Homo sapiens] 31 2.6
gi|226246535 zinc finger protein 407 isoform 2 [Homo sapiens] 31 2.6
gi|134133288 zinc finger protein 407 isoform 1 [Homo sapiens] 31 2.6
gi|102469034 janus kinase 1 [Homo sapiens] 30 4.5
gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3 ... 30 5.9
gi|38570149 WWC family member 3 [Homo sapiens] 30 5.9
gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 29 7.7
gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 29 7.7
gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 29 7.7
gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptid... 29 7.7
>gi|4758426 guanine deaminase [Homo sapiens]
Length = 454
Score = 913 bits (2360), Expect = 0.0
Identities = 454/454 (100%), Positives = 454/454 (100%)
Query: 1 MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCF 60
MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCF
Sbjct: 1 MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCF 60
Query: 61 KPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFA 120
KPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFA
Sbjct: 61 KPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFA 120
Query: 121 EEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEY 180
EEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEY
Sbjct: 121 EEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEY 180
Query: 181 KETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSH 240
KETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSH
Sbjct: 181 KETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSH 240
Query: 241 ISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAH 300
ISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAH
Sbjct: 241 ISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAH 300
Query: 301 CPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNE 360
CPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNE
Sbjct: 301 CPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNE 360
Query: 361 KSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDI 420
KSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDI
Sbjct: 361 KSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDI 420
Query: 421 SEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV 454
SEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV
Sbjct: 421 SEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV 454
>gi|223972677 amidohydrolase domain containing 1 [Homo sapiens]
Length = 426
Score = 36.6 bits (83), Expect = 0.048
Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 14/112 (12%)
Query: 317 EVLKHEVKIGLGTDV-AGGYSYSMLDAIRRAVMVSNILLINKVNEKSLTLKEVFRLATLG 375
++L V + LG+D Y +SM MV ++ +N +++ E AT+
Sbjct: 321 KMLDEGVIVALGSDFNPNAYCFSM-------PMVMHLACVNM----RMSMPEALAAATIN 369
Query: 376 GSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDISEAVIQK 427
+ ALG G+ EVGK+ D I+IN + I F G ++ E VI K
Sbjct: 370 AAYALGKSHTHGSLEVGKQGDLIIINSSRWEHLIYQFGGHH--ELIEYVIAK 419
>gi|197313748 SET domain containing 2 [Homo sapiens]
Length = 2564
Score = 36.2 bits (82), Expect = 0.063
Identities = 55/239 (23%), Positives = 101/239 (42%), Gaps = 30/239 (12%)
Query: 142 FATIHTDSSLLLADITDKFGQRAFVGKVCM---------------DLNDTFPEYKETTEE 186
F T TD+ L+ +D + + + + K CM DL+DT +K+ +E
Sbjct: 686 FCTSKTDAVLMTSDDSVTGSELSPLVKACMLSSNGFQNISRCKEKDLDDTCMLHKK-SES 744
Query: 187 SIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSHISENRD 246
+ETE VS K S P++T +S + + + + KT+D I ++++
Sbjct: 745 PFRETEPLVSPHQDKLMS--MPVMTVDYSKTVVKEPVDTRVSCCKTKDSDIYCTLNDSNP 802
Query: 247 EV--EAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAHCPNS 304
+ +N+ PS +S N L +K V+ L+ E SI ++
Sbjct: 803 SLCNSEAENIEPSVMKISSNSFMNVHLESKPVICDSRNLTDHSKFACEEYKQSIGSTSSA 862
Query: 305 NLSL---------SSGFLNVLEVLKHEVKIGLGTDVAGGYSYS-MLDAIRRAVMVSNIL 353
+++ SSG + L+ L +K+ T + G + S +LDA+ ++ S L
Sbjct: 863 SVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLLKCGENTSPVLDAVLKSKKSSEFL 921
>gi|226246537 zinc finger protein 407 isoform 3 [Homo sapiens]
Length = 1660
Score = 30.8 bits (68), Expect = 2.6
Identities = 42/204 (20%), Positives = 76/204 (37%), Gaps = 22/204 (10%)
Query: 132 LKNGTTTACYFATIHTDSSLLLADIT-DKFGQRAF-----VGKVCMDLNDTFPEYKETTE 185
LK+G C T ++SS+ I D+ G+ F VG C+ N P +T
Sbjct: 84 LKSGKQGICRLET--SESSVTEGGIALDETGKETFLSDCTVGGTCLP-NALSPSCNFSTI 140
Query: 186 ESIK---ETERF-VSEMLQKNYSRVKPIVTPRFSLSCSE---------TLMGELGNIAKT 232
+ + +TE+ EM+ + R P S+SC+ ++ G L +
Sbjct: 141 DVVSLKTDTEKTSAQEMVSLDLERESPFPPKEISVSCTIGNVDTVLKCSICGHLFSSCSD 200
Query: 233 RDLHIQSHISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFH 292
+ H +SH+ + ++ + + ++ K K C E N+ +
Sbjct: 201 LEKHAESHMQQPKEHTCCHCSHKAESSSALHMHIKQAHGPQKVFSCDLCGFQCSEENLLN 260
Query: 293 ERGASIAHCPNSNLSLSSGFLNVL 316
H NL+ GF+ +L
Sbjct: 261 AHYLGKTHLRRQNLAARGGFVQIL 284
>gi|226246535 zinc finger protein 407 isoform 2 [Homo sapiens]
Length = 1815
Score = 30.8 bits (68), Expect = 2.6
Identities = 42/204 (20%), Positives = 76/204 (37%), Gaps = 22/204 (10%)
Query: 132 LKNGTTTACYFATIHTDSSLLLADIT-DKFGQRAF-----VGKVCMDLNDTFPEYKETTE 185
LK+G C T ++SS+ I D+ G+ F VG C+ N P +T
Sbjct: 84 LKSGKQGICRLET--SESSVTEGGIALDETGKETFLSDCTVGGTCLP-NALSPSCNFSTI 140
Query: 186 ESIK---ETERF-VSEMLQKNYSRVKPIVTPRFSLSCSE---------TLMGELGNIAKT 232
+ + +TE+ EM+ + R P S+SC+ ++ G L +
Sbjct: 141 DVVSLKTDTEKTSAQEMVSLDLERESPFPPKEISVSCTIGNVDTVLKCSICGHLFSSCSD 200
Query: 233 RDLHIQSHISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFH 292
+ H +SH+ + ++ + + ++ K K C E N+ +
Sbjct: 201 LEKHAESHMQQPKEHTCCHCSHKAESSSALHMHIKQAHGPQKVFSCDLCGFQCSEENLLN 260
Query: 293 ERGASIAHCPNSNLSLSSGFLNVL 316
H NL+ GF+ +L
Sbjct: 261 AHYLGKTHLRRQNLAARGGFVQIL 284
>gi|134133288 zinc finger protein 407 isoform 1 [Homo sapiens]
Length = 2248
Score = 30.8 bits (68), Expect = 2.6
Identities = 42/204 (20%), Positives = 76/204 (37%), Gaps = 22/204 (10%)
Query: 132 LKNGTTTACYFATIHTDSSLLLADIT-DKFGQRAF-----VGKVCMDLNDTFPEYKETTE 185
LK+G C T ++SS+ I D+ G+ F VG C+ N P +T
Sbjct: 84 LKSGKQGICRLET--SESSVTEGGIALDETGKETFLSDCTVGGTCLP-NALSPSCNFSTI 140
Query: 186 ESIK---ETERF-VSEMLQKNYSRVKPIVTPRFSLSCSE---------TLMGELGNIAKT 232
+ + +TE+ EM+ + R P S+SC+ ++ G L +
Sbjct: 141 DVVSLKTDTEKTSAQEMVSLDLERESPFPPKEISVSCTIGNVDTVLKCSICGHLFSSCSD 200
Query: 233 RDLHIQSHISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFH 292
+ H +SH+ + ++ + + ++ K K C E N+ +
Sbjct: 201 LEKHAESHMQQPKEHTCCHCSHKAESSSALHMHIKQAHGPQKVFSCDLCGFQCSEENLLN 260
Query: 293 ERGASIAHCPNSNLSLSSGFLNVL 316
H NL+ GF+ +L
Sbjct: 261 AHYLGKTHLRRQNLAARGGFVQIL 284
>gi|102469034 janus kinase 1 [Homo sapiens]
Length = 1154
Score = 30.0 bits (66), Expect = 4.5
Identities = 40/196 (20%), Positives = 74/196 (37%), Gaps = 22/196 (11%)
Query: 162 QRAFVGKVCMDLNDTFPEYKETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLS--CS 219
QR F + D+N + + E TE + ++ R++ + F C
Sbjct: 834 QRPFFRAIMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCR 893
Query: 220 ETLMGE-LGNIAKTRDLHIQS---HISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKT 275
G+ G + L +S HI++ + E+E ++NLY N++ K
Sbjct: 894 YDPEGDNTGEQVAVKSLKPESGGNHIADLKKEIEILRNLY-----------HENIVKYKG 942
Query: 276 VMAHGCYLSAEELNVFHERGASIAHCPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGY 335
+ + + F G+ + P + + N+ + LK+ V+I G D G
Sbjct: 943 ICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKI-----NLKQQLKYAVQICKGMDYLGSR 997
Query: 336 SYSMLDAIRRAVMVSN 351
Y D R V+V +
Sbjct: 998 QYVHRDLAARNVLVES 1013
>gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3
subunit [Homo sapiens]
Length = 1091
Score = 29.6 bits (65), Expect = 5.9
Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 6/66 (9%)
Query: 372 ATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDISEAVIQKFLYL 431
A+L G ++ D E N + IL++ + + GDFFG+I AV+ K L +
Sbjct: 839 ASLDGKCSISCDDETVNCYLIDNNGFILVSEDYTQT------GDFFGEIEGAVMNKLLTM 892
Query: 432 GDDRNI 437
G + I
Sbjct: 893 GSFKRI 898
>gi|38570149 WWC family member 3 [Homo sapiens]
Length = 1092
Score = 29.6 bits (65), Expect = 5.9
Identities = 34/156 (21%), Positives = 65/156 (41%), Gaps = 21/156 (13%)
Query: 115 QNIDFAEEVYTRVVRRTLKNGTTTACYFATIHT----DSSLLLADITDKFGQRAFVGKVC 170
Q + A+E Y ++ + + + A F+ T D + A+I + + + + +
Sbjct: 48 QRFELAQEEYQQLHKMCEDDSRSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKREL 107
Query: 171 MDLNDTFPEYKETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIA 230
+ +YKE E+++E +R +S + L ++ +M EL I
Sbjct: 108 TQMKQEL-QYKEKGVETLQEIDRKMSS------------THTSYKLDEAQAIMSELRTIK 154
Query: 231 KTRDLHIQSHISENRDEVEAVKNLYPSYKNYTSVYD 266
K I + E RD + ++ L S+KN SV D
Sbjct: 155 KA----ICTGEKERRDLMHSLAKLTDSFKNSCSVTD 186
>gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4470
Score = 29.3 bits (64), Expect = 7.7
Identities = 41/193 (21%), Positives = 80/193 (41%), Gaps = 31/193 (16%)
Query: 216 LSCSETLMGELGNIAKT------------RDLHIQSHISENRDEVEAV--------KNLY 255
L+ E L+ ++ N+A+ DL + + E R+EV ++ +
Sbjct: 934 LALIEGLVNDIYNVARLIPRLAKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQ 993
Query: 256 PSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAHCPNSNLSLSSGFLNV 315
S++ Y+ ++ N K + +GC ++AE+L+ + + +I P L+ ++
Sbjct: 994 DSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTD--DTIPKTP-PTLAQFQEQIDS 1050
Query: 316 LEVLKHEVKIGLGTDVAGG--------YSYSMLDAIRRAVMVSNILLINKVNEKSLTLKE 367
E L EV T V G + ++L IRR + L N V L+
Sbjct: 1051 YEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEA 1110
Query: 368 VFRLATLGGSQAL 380
++A +G ++ L
Sbjct: 1111 FMKVARMGLTKPL 1123
>gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 29.3 bits (64), Expect = 7.7
Identities = 41/193 (21%), Positives = 80/193 (41%), Gaps = 31/193 (16%)
Query: 216 LSCSETLMGELGNIAKT------------RDLHIQSHISENRDEVEAV--------KNLY 255
L+ E L+ ++ N+A+ DL + + E R+EV ++ +
Sbjct: 925 LALIEGLVNDIYNVARLIPRLAKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQ 984
Query: 256 PSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAHCPNSNLSLSSGFLNV 315
S++ Y+ ++ N K + +GC ++AE+L+ + + +I P L+ ++
Sbjct: 985 DSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTD--DTIPKTP-PTLAQFQEQIDS 1041
Query: 316 LEVLKHEVKIGLGTDVAGG--------YSYSMLDAIRRAVMVSNILLINKVNEKSLTLKE 367
E L EV T V G + ++L IRR + L N V L+
Sbjct: 1042 YEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEA 1101
Query: 368 VFRLATLGGSQAL 380
++A +G ++ L
Sbjct: 1102 FMKVARMGLTKPL 1114
>gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 29.3 bits (64), Expect = 7.7
Identities = 41/193 (21%), Positives = 80/193 (41%), Gaps = 31/193 (16%)
Query: 216 LSCSETLMGELGNIAKT------------RDLHIQSHISENRDEVEAV--------KNLY 255
L+ E L+ ++ N+A+ DL + + E R+EV ++ +
Sbjct: 925 LALIEGLVNDIYNVARLIPRLAKDRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQ 984
Query: 256 PSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAHCPNSNLSLSSGFLNV 315
S++ Y+ ++ N K + +GC ++AE+L+ + + +I P L+ ++
Sbjct: 985 DSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTD--DTIPKTP-PTLAQFQEQIDS 1041
Query: 316 LEVLKHEVKIGLGTDVAGG--------YSYSMLDAIRRAVMVSNILLINKVNEKSLTLKE 367
E L EV T V G + ++L IRR + L N V L+
Sbjct: 1042 YEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEA 1101
Query: 368 VFRLATLGGSQAL 380
++A +G ++ L
Sbjct: 1102 FMKVARMGLTKPL 1114
>gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptide
[Homo sapiens]
Length = 1686
Score = 29.3 bits (64), Expect = 7.7
Identities = 13/29 (44%), Positives = 17/29 (58%), Gaps = 1/29 (3%)
Query: 87 QYSFAGSSIDLPLLEWLTKYTFPAEHRFQ 115
+Y GS D PL EWL KY P+E ++
Sbjct: 1199 EYGVTGSFKDKPLAEWLRKYN-PSEEEYE 1226
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,656,176
Number of Sequences: 37866
Number of extensions: 645631
Number of successful extensions: 1463
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1459
Number of HSP's gapped (non-prelim): 14
length of query: 454
length of database: 18,247,518
effective HSP length: 106
effective length of query: 348
effective length of database: 14,233,722
effective search space: 4953335256
effective search space used: 4953335256
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.