Search of human proteins with 46249410

Search of human proteins with 46249410

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46249410 lecithin retinol acyltransferase [Homo sapiens]
         (230 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46249410 lecithin retinol acyltransferase [Homo sapiens]           457   e-129
gi|9966859 HRAS-like suppressor [Homo sapiens]                         67   1e-11
gi|8923526 HRAS-like suppressor 2 [Homo sapiens]                       66   2e-11
gi|16905367 HRAS-like suppressor family, member 5 isoform 1 [Hom...    57   1e-08
gi|226491950 HRAS-like suppressor family, member 5 isoform 2 [Ho...    57   1e-08
gi|149588791 retinoic acid receptor responder (tazarotene induce...    57   2e-08
gi|189571621 HRAS-like suppressor 3 [Homo sapiens]                     55   7e-08
gi|189571618 HRAS-like suppressor 3 [Homo sapiens]                     55   7e-08
gi|226528146 HRAS-like suppressor family, member 5 isoform 3 [Ho...    38   0.006
gi|28557798 family with sequence similarity 84, member B [Homo s...    33   0.16 
gi|21553329 family with sequence similarity 84, member A [Homo s...    30   2.3  
gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Ho...    29   3.9  
gi|42476076 hypothetical protein LOC22878 [Homo sapiens]               28   5.0  

>gi|46249410 lecithin retinol acyltransferase [Homo sapiens]
          Length = 230

 Score =  457 bits (1177), Expect = e-129
 Identities = 230/230 (100%), Positives = 230/230 (100%)

Query: 1   MKNPMLEVVSLLLEKLLLISNFTLFSSGAAGEDKGRNSFYETSSFHRGDVLEVPRTHLTH 60
           MKNPMLEVVSLLLEKLLLISNFTLFSSGAAGEDKGRNSFYETSSFHRGDVLEVPRTHLTH
Sbjct: 1   MKNPMLEVVSLLLEKLLLISNFTLFSSGAAGEDKGRNSFYETSSFHRGDVLEVPRTHLTH 60

Query: 61  YGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVASIRVDTVEDFAYGA 120
           YGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVASIRVDTVEDFAYGA
Sbjct: 61  YGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVASIRVDTVEDFAYGA 120

Query: 121 NILVNHLDESLQKKALLNEEVARRAEKLLGFTPYSLLWNNCEHFVTYCRYGTPISPQSDK 180
           NILVNHLDESLQKKALLNEEVARRAEKLLGFTPYSLLWNNCEHFVTYCRYGTPISPQSDK
Sbjct: 121 NILVNHLDESLQKKALLNEEVARRAEKLLGFTPYSLLWNNCEHFVTYCRYGTPISPQSDK 180

Query: 181 FCETVKIIIRDQRSVLASAVLGLASIVCTGLVSYTTLPAIFIPFFLWMAG 230
           FCETVKIIIRDQRSVLASAVLGLASIVCTGLVSYTTLPAIFIPFFLWMAG
Sbjct: 181 FCETVKIIIRDQRSVLASAVLGLASIVCTGLVSYTTLPAIFIPFFLWMAG 230


>gi|9966859 HRAS-like suppressor [Homo sapiens]
          Length = 168

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 47/142 (33%), Positives = 75/142 (52%), Gaps = 14/142 (9%)

Query: 48  GDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVAS 107
           GD++EV R    H+ +YLGD  V ++ P  +  +       + V S+K L+   ++K   
Sbjct: 18  GDLIEVFRPGYQHWALYLGDGYVINIAP--VDGIPASFTSAKSVFSSKALVKMQLLK--- 72

Query: 108 IRVDTVEDFAYGANILVNHLDESLQKKALLNEEVARRAEKLLGF-TPYSLLWNNCEHFVT 166
              D V +  Y  N   N  DE+     +  EE+ +R+E ++G    Y+LL NNCEHFVT
Sbjct: 73  ---DVVGNDTYRIN---NKYDETYPPLPV--EEIIKRSEFVIGQEVAYNLLVNNCEHFVT 124

Query: 167 YCRYGTPISPQSDKFCETVKII 188
             RYG  +S Q+++   TV+ +
Sbjct: 125 LLRYGEGVSEQANRAISTVEFV 146


>gi|8923526 HRAS-like suppressor 2 [Homo sapiens]
          Length = 162

 Score = 66.2 bits (160), Expect = 2e-11
 Identities = 48/161 (29%), Positives = 77/161 (47%), Gaps = 22/161 (13%)

Query: 48  GDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVAS 107
           GD++E+ R    H+ IY+GD  V H+ P   +A            +    +L  +   A 
Sbjct: 11  GDLIEISRFGYAHWAIYVGDGYVVHLAPASEIA-----------GAGAASVLSALTNKAI 59

Query: 108 IRVDTVEDFAYGANILVNHLDESLQKKALLNEEVARRAEKLLGFT-PYSLLWNNCEHFVT 166
           ++ + +   A G N  VN+  +  +   L + ++ +RAE+L+G   PYSL  +NCEHFV 
Sbjct: 60  VKKELLSVVAGGDNYRVNNKHDD-RYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVN 118

Query: 167 YCRYGTPISPQSDKFCETVKIIIRDQRSVLASAVLGLASIV 207
           + RYG   S Q      TV +         A+ +L  AS+V
Sbjct: 119 HLRYGVSRSDQVTGAVTTVGV---------AAGLLAAASLV 150


>gi|16905367 HRAS-like suppressor family, member 5 isoform 1 [Homo
           sapiens]
          Length = 279

 Score = 57.0 bits (136), Expect = 1e-08
 Identities = 36/130 (27%), Positives = 62/130 (47%), Gaps = 13/130 (10%)

Query: 48  GDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVAS 107
           GD++E+ R    H+ IY+ D+ V H+ P    +   ++G    + SN+          A 
Sbjct: 133 GDLIEIFRIGYEHWAIYVEDDCVVHLAPP---SEEFEVGSITSIFSNR----------AV 179

Query: 108 IRVDTVEDFAYGANILVNHLDESLQKKALLNEEVARRAEKLLGFTPYSLLWNNCEHFVTY 167
           ++   +ED  +G +  VN+  +       +++ + R  + +     YSL+  NCEHFV  
Sbjct: 180 VKYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNCEHFVNG 239

Query: 168 CRYGTPISPQ 177
            RYG P S Q
Sbjct: 240 LRYGVPRSQQ 249


>gi|226491950 HRAS-like suppressor family, member 5 isoform 2 [Homo
           sapiens]
          Length = 269

 Score = 57.0 bits (136), Expect = 1e-08
 Identities = 36/130 (27%), Positives = 62/130 (47%), Gaps = 13/130 (10%)

Query: 48  GDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVAS 107
           GD++E+ R    H+ IY+ D+ V H+ P    +   ++G    + SN+          A 
Sbjct: 123 GDLIEIFRIGYEHWAIYVEDDCVVHLAPP---SEEFEVGSITSIFSNR----------AV 169

Query: 108 IRVDTVEDFAYGANILVNHLDESLQKKALLNEEVARRAEKLLGFTPYSLLWNNCEHFVTY 167
           ++   +ED  +G +  VN+  +       +++ + R  + +     YSL+  NCEHFV  
Sbjct: 170 VKYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNCEHFVNG 229

Query: 168 CRYGTPISPQ 177
            RYG P S Q
Sbjct: 230 LRYGVPRSQQ 239


>gi|149588791 retinoic acid receptor responder (tazarotene induced)
           3 [Homo sapiens]
          Length = 164

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 38/135 (28%), Positives = 65/135 (48%), Gaps = 15/135 (11%)

Query: 48  GDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVAS 107
           GD++E+ R    H+ +Y+GD  V H+ P            ++   +    +  V+   A 
Sbjct: 11  GDLIEIFRLGYEHWALYIGDGYVIHLAPP-----------SEYPGAGSSSVFSVLSNSAE 59

Query: 108 IRVDTVEDFAYGANILVNH-LDESLQKKALLNEEVARRAEKLLGFT-PYSLLWNNCEHFV 165
           ++ + +ED   G    VN+ LD   Q + +  E +   A++++G    YS++  NCEHFV
Sbjct: 60  VKRERLEDVVGGCCYRVNNSLDHEYQPRPV--EVIISSAKEMVGQKMKYSIVSRNCEHFV 117

Query: 166 TYCRYGTPISPQSDK 180
           T  RYG     Q +K
Sbjct: 118 TQLRYGKSRCKQVEK 132


>gi|189571621 HRAS-like suppressor 3 [Homo sapiens]
          Length = 162

 Score = 54.7 bits (130), Expect = 7e-08
 Identities = 43/166 (25%), Positives = 74/166 (44%), Gaps = 24/166 (14%)

Query: 48  GDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVAS 107
           GD++E+ R    H+ IY+GD  V H+ P            ++   +    ++  +   A 
Sbjct: 11  GDLIEIFRPFYRHWAIYVGDGYVVHLAPP-----------SEVAGAGAASVMSALTDKAI 59

Query: 108 IRVDTVEDFAYGANILVNHLDESLQKKALLNEEVARRAEKLLG-FTPYSLLWNNCEHFVT 166
           ++ + + D A      VN+  +  +   L   ++ +RAE+L+G    Y L   NCEHFV 
Sbjct: 60  VKKELLYDVAGSDKYQVNNKHDD-KYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVN 118

Query: 167 YCRYGTPISPQSDKFCETVKIIIRDQRSVLASAVLGLASIVCTGLV 212
             RYG   S Q           +RD     + A +GLA++   G++
Sbjct: 119 ELRYGVARSDQ-----------VRDVIIAASVAGMGLAAMSLIGVM 153


>gi|189571618 HRAS-like suppressor 3 [Homo sapiens]
          Length = 162

 Score = 54.7 bits (130), Expect = 7e-08
 Identities = 43/166 (25%), Positives = 74/166 (44%), Gaps = 24/166 (14%)

Query: 48  GDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVAS 107
           GD++E+ R    H+ IY+GD  V H+ P            ++   +    ++  +   A 
Sbjct: 11  GDLIEIFRPFYRHWAIYVGDGYVVHLAPP-----------SEVAGAGAASVMSALTDKAI 59

Query: 108 IRVDTVEDFAYGANILVNHLDESLQKKALLNEEVARRAEKLLG-FTPYSLLWNNCEHFVT 166
           ++ + + D A      VN+  +  +   L   ++ +RAE+L+G    Y L   NCEHFV 
Sbjct: 60  VKKELLYDVAGSDKYQVNNKHDD-KYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVN 118

Query: 167 YCRYGTPISPQSDKFCETVKIIIRDQRSVLASAVLGLASIVCTGLV 212
             RYG   S Q           +RD     + A +GLA++   G++
Sbjct: 119 ELRYGVARSDQ-----------VRDVIIAASVAGMGLAAMSLIGVM 153


>gi|226528146 HRAS-like suppressor family, member 5 isoform 3 [Homo
           sapiens]
          Length = 253

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 26/114 (22%), Positives = 52/114 (45%), Gaps = 13/114 (11%)

Query: 48  GDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVAS 107
           GD++E+ R    H+ IY+ D+ V H+ P    +   ++G    + SN+          A 
Sbjct: 133 GDLIEIFRIGYEHWAIYVEDDCVVHLAPP---SEEFEVGSITSIFSNR----------AV 179

Query: 108 IRVDTVEDFAYGANILVNHLDESLQKKALLNEEVARRAEKLLGFTPYSLLWNNC 161
           ++   +ED  +G +  VN+  +       +++ + R  + +     YSL+  NC
Sbjct: 180 VKYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNC 233


>gi|28557798 family with sequence similarity 84, member B [Homo
           sapiens]
          Length = 310

 Score = 33.5 bits (75), Expect = 0.16
 Identities = 32/128 (25%), Positives = 49/128 (38%), Gaps = 39/128 (30%)

Query: 48  GDVLE-VPRTHLTHYGIYLGDNRVAHM--MPDILLALTD-DMGRTQKVVSNKRLILGVIV 103
           GD++E V +    H+ +Y+G+ +V H+  +  I   LTD   GR  +VV+          
Sbjct: 119 GDLVEFVSQAQYPHWAVYVGNFQVVHLHRLEVINSFLTDASQGRRGRVVN---------- 168

Query: 104 KVASIRVDTVEDFAYGANILVNHLDESLQKKALLNEEVARRAEKLLGFTPYSLLWNNCEH 163
                                    +  + K L +  V R A   +G     L W N E 
Sbjct: 169 -------------------------DLYRYKPLSSSAVVRNALAHVGAKERELSWRNSES 203

Query: 164 FVTYCRYG 171
           F  +CRYG
Sbjct: 204 FAAWCRYG 211


>gi|21553329 family with sequence similarity 84, member A [Homo
           sapiens]
          Length = 292

 Score = 29.6 bits (65), Expect = 2.3
 Identities = 32/160 (20%), Positives = 57/160 (35%), Gaps = 44/160 (27%)

Query: 24  LFSSGAAGEDKGRNSFYETSSF----HRGDVLEV--------PRTHLTHYGIYLGDNRVA 71
           +FS  + G      S Y  ++       GD+LE+        P     H+ +Y+G  ++ 
Sbjct: 95  IFSKVSGGPQGADLSVYAVTALPALCEPGDLLELLWLQPAPEPPAPAPHWAVYVGGGQII 154

Query: 72  HMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVASIRVDTVEDFAYGANILVNHLDESL 131
           H+                                  IR D++  +  GA  +   ++   
Sbjct: 155 HLHQ------------------------------GEIRQDSL--YEAGAANVGRVVNSWY 182

Query: 132 QKKALLNEEVARRAEKLLGFTPYSLLWNNCEHFVTYCRYG 171
           + + L+ E V + A   LG     + W N E F  +CR+G
Sbjct: 183 RYRPLVAELVVQNACGHLGLKSEEICWTNSESFAAWCRFG 222


>gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Homo
           sapiens]
          Length = 926

 Score = 28.9 bits (63), Expect = 3.9
 Identities = 30/135 (22%), Positives = 51/135 (37%), Gaps = 5/135 (3%)

Query: 52  EVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVASIRVD 111
           E+ + H  H G+   +    ++     L L        +  SN  +++GV+     I  +
Sbjct: 187 EIAKLHQQHIGLSPAEAEFNYLNTARTLELYGVEFHYARDQSNNEIMIGVMSGGILIYKN 246

Query: 112 TVEDFAYGANILVNHLDESLQKKALLNEEVARRAEKLLGFTPYSL-----LWNNCEHFVT 166
            V    +    +V    +  Q    L +E+    E LLGF   +      LW  C    T
Sbjct: 247 RVRMNTFPWLKIVKISFKCKQFFIQLRKELHESRETLLGFNMVNYRACKNLWKACVEHHT 306

Query: 167 YCRYGTPISPQSDKF 181
           + R   P+ PQ + F
Sbjct: 307 FFRLDRPLPPQKNFF 321


>gi|42476076 hypothetical protein LOC22878 [Homo sapiens]
          Length = 1435

 Score = 28.5 bits (62), Expect = 5.0
 Identities = 17/71 (23%), Positives = 30/71 (42%), Gaps = 12/71 (16%)

Query: 172  TPISPQSDKFCETVKIIIRDQRSVLASAVLGLASI---VCTG---------LVSYTTLPA 219
            TP+SP + + C   K ++ D  SV  + +   +S+   + TG         L     LP 
Sbjct: 968  TPLSPSASENCSAYKTVVTDATSVCTALISSASSVDFGIGTGSQPEVIPVPLPDTVLLPG 1027

Query: 220  IFIPFFLWMAG 230
              +   +W+ G
Sbjct: 1028 ASVQLPMWLRG 1038


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.138    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,824,282
Number of Sequences: 37866
Number of extensions: 306845
Number of successful extensions: 565
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 544
Number of HSP's gapped (non-prelim): 14
length of query: 230
length of database: 18,247,518
effective HSP length: 99
effective length of query: 131
effective length of database: 14,498,784
effective search space: 1899340704
effective search space used: 1899340704
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.