Guide to the Human Genome
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Search of human proteins with 46094086

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46094086 chromosome 6 open reading frame 106 isoform b [Homo
sapiens]
         (232 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46094086 chromosome 6 open reading frame 106 isoform b [Homo ...   480   e-136
gi|13236514 chromosome 6 open reading frame 106 isoform a [Homo ...   268   4e-72
gi|16753207 ubiquilin 2 [Homo sapiens]                                 30   1.3  
gi|154813197 talpid3 protein [Homo sapiens]                            30   1.3  
gi|239049540 FCH domain only 1 isoform c [Homo sapiens]                30   2.3  
gi|239049457 FCH domain only 1 isoform b [Homo sapiens]                30   2.3  
gi|29789054 FCH domain only 1 isoform b [Homo sapiens]                 30   2.3  
gi|239049440 FCH domain only 1 isoform a [Homo sapiens]                30   2.3  
gi|55750053 atrophin-1 [Homo sapiens]                                  29   3.0  
gi|55750041 atrophin-1 [Homo sapiens]                                  29   3.0  
gi|14110378 neighbor of BRCA1 gene 1 [Homo sapiens]                    29   3.9  
gi|14110375 neighbor of BRCA1 gene 1 [Homo sapiens]                    29   3.9  
gi|14110381 neighbor of BRCA1 gene 1 [Homo sapiens]                    29   3.9  
gi|148236531 hypothetical protein LOC339779 [Homo sapiens]             28   5.1  
gi|33188443 microfilament and actin filament cross-linker protei...    28   6.7  
gi|33188445 microfilament and actin filament cross-linker protei...    28   6.7  
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re...    28   8.7  
gi|54792100 erbB-3 isoform 1 precursor [Homo sapiens]                  28   8.7  

>gi|46094086 chromosome 6 open reading frame 106 isoform b [Homo
           sapiens]
          Length = 232

 Score =  480 bits (1235), Expect = e-136
 Identities = 232/232 (100%), Positives = 232/232 (100%)

Query: 1   MEGMDVDLDPELMQKFSCLGTTDKDVLISEFQRLLGFQLNPAGCAFFLDMTNWNLQAAIG 60
           MEGMDVDLDPELMQKFSCLGTTDKDVLISEFQRLLGFQLNPAGCAFFLDMTNWNLQAAIG
Sbjct: 1   MEGMDVDLDPELMQKFSCLGTTDKDVLISEFQRLLGFQLNPAGCAFFLDMTNWNLQAAIG 60

Query: 61  AYYDFESPNISVPSMSFVEDVTIGEGESIPPDTQFVKTWRIQNSDVIWVILSVEVGGLLG 120
           AYYDFESPNISVPSMSFVEDVTIGEGESIPPDTQFVKTWRIQNSDVIWVILSVEVGGLLG
Sbjct: 61  AYYDFESPNISVPSMSFVEDVTIGEGESIPPDTQFVKTWRIQNSDVIWVILSVEVGGLLG 120

Query: 121 VTQQLSSFETEFNTQPHRKVEGNFNPFASPQKNRQSDENNLKDPGGSEFDSISKNTWAPA 180
           VTQQLSSFETEFNTQPHRKVEGNFNPFASPQKNRQSDENNLKDPGGSEFDSISKNTWAPA
Sbjct: 121 VTQQLSSFETEFNTQPHRKVEGNFNPFASPQKNRQSDENNLKDPGGSEFDSISKNTWAPA 180

Query: 181 PDTWAPAPDQTEQDQNRLSQNSVNLSPSSHANNLSVVTYSKGLHGPYPFGQS 232
           PDTWAPAPDQTEQDQNRLSQNSVNLSPSSHANNLSVVTYSKGLHGPYPFGQS
Sbjct: 181 PDTWAPAPDQTEQDQNRLSQNSVNLSPSSHANNLSVVTYSKGLHGPYPFGQS 232


>gi|13236514 chromosome 6 open reading frame 106 isoform a [Homo
           sapiens]
          Length = 298

 Score =  268 bits (684), Expect = 4e-72
 Identities = 128/128 (100%), Positives = 128/128 (100%)

Query: 105 DVIWVILSVEVGGLLGVTQQLSSFETEFNTQPHRKVEGNFNPFASPQKNRQSDENNLKDP 164
           DVIWVILSVEVGGLLGVTQQLSSFETEFNTQPHRKVEGNFNPFASPQKNRQSDENNLKDP
Sbjct: 171 DVIWVILSVEVGGLLGVTQQLSSFETEFNTQPHRKVEGNFNPFASPQKNRQSDENNLKDP 230

Query: 165 GGSEFDSISKNTWAPAPDTWAPAPDQTEQDQNRLSQNSVNLSPSSHANNLSVVTYSKGLH 224
           GGSEFDSISKNTWAPAPDTWAPAPDQTEQDQNRLSQNSVNLSPSSHANNLSVVTYSKGLH
Sbjct: 231 GGSEFDSISKNTWAPAPDTWAPAPDQTEQDQNRLSQNSVNLSPSSHANNLSVVTYSKGLH 290

Query: 225 GPYPFGQS 232
           GPYPFGQS
Sbjct: 291 GPYPFGQS 298



 Score =  216 bits (551), Expect = 1e-56
 Identities = 104/104 (100%), Positives = 104/104 (100%)

Query: 1   MEGMDVDLDPELMQKFSCLGTTDKDVLISEFQRLLGFQLNPAGCAFFLDMTNWNLQAAIG 60
           MEGMDVDLDPELMQKFSCLGTTDKDVLISEFQRLLGFQLNPAGCAFFLDMTNWNLQAAIG
Sbjct: 1   MEGMDVDLDPELMQKFSCLGTTDKDVLISEFQRLLGFQLNPAGCAFFLDMTNWNLQAAIG 60

Query: 61  AYYDFESPNISVPSMSFVEDVTIGEGESIPPDTQFVKTWRIQNS 104
           AYYDFESPNISVPSMSFVEDVTIGEGESIPPDTQFVKTWRIQNS
Sbjct: 61  AYYDFESPNISVPSMSFVEDVTIGEGESIPPDTQFVKTWRIQNS 104


>gi|16753207 ubiquilin 2 [Homo sapiens]
          Length = 624

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 23/75 (30%), Positives = 30/75 (40%), Gaps = 5/75 (6%)

Query: 145 NPFASPQKNRQSDENNLKDPGGSEFDSISKNTWAPAPDTWAPAPDQTEQDQNRLSQNSVN 204
           NPFAS   +  S E     P  +E      N WAP P T + A   T       S NS  
Sbjct: 290 NPFASVGSSSSSGEGT--QPSRTENRDPLPNPWAPPPATQSSATTSTTTSTGSGSGNS-- 345

Query: 205 LSPSSHANNLSVVTY 219
            S ++  N ++   Y
Sbjct: 346 -SSNATGNTVAAANY 359


>gi|154813197 talpid3 protein [Homo sapiens]
          Length = 1472

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 23/91 (25%), Positives = 40/91 (43%), Gaps = 7/91 (7%)

Query: 131 EFNTQPHRKVEGNFNPFASPQKNRQSDENNLKDPGGSEFDSISKNTWAPAPDTWAPAP-- 188
           +++ +P     G+ NP  S      S +  LK+   + FD        PAP  +AP P  
Sbjct: 295 KYSVKPEHPNLGSCNP--SLYNTFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVS 352

Query: 189 --DQTEQDQNRLSQNSVNLSPSSHANNLSVV 217
             D+  + +N L +   N+  S H  N+ ++
Sbjct: 353 RDDELSKRENLLEEKE-NMEVSCHRGNVRLL 382


>gi|239049540 FCH domain only 1 isoform c [Homo sapiens]
          Length = 839

 Score = 29.6 bits (65), Expect = 2.3
 Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 3/41 (7%)

Query: 148 ASPQKNRQSDENNLKDPGGSEFDSISKNTWAPAPDTWAPAP 188
           +SP     S   N++D G    DS S     P+PD+W P P
Sbjct: 409 SSPSPFSSSSPENVEDSG---LDSPSHAAPGPSPDSWVPRP 446


>gi|239049457 FCH domain only 1 isoform b [Homo sapiens]
          Length = 889

 Score = 29.6 bits (65), Expect = 2.3
 Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 3/41 (7%)

Query: 148 ASPQKNRQSDENNLKDPGGSEFDSISKNTWAPAPDTWAPAP 188
           +SP     S   N++D G    DS S     P+PD+W P P
Sbjct: 459 SSPSPFSSSSPENVEDSG---LDSPSHAAPGPSPDSWVPRP 496


>gi|29789054 FCH domain only 1 isoform b [Homo sapiens]
          Length = 889

 Score = 29.6 bits (65), Expect = 2.3
 Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 3/41 (7%)

Query: 148 ASPQKNRQSDENNLKDPGGSEFDSISKNTWAPAPDTWAPAP 188
           +SP     S   N++D G    DS S     P+PD+W P P
Sbjct: 459 SSPSPFSSSSPENVEDSG---LDSPSHAAPGPSPDSWVPRP 496


>gi|239049440 FCH domain only 1 isoform a [Homo sapiens]
          Length = 891

 Score = 29.6 bits (65), Expect = 2.3
 Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 3/41 (7%)

Query: 148 ASPQKNRQSDENNLKDPGGSEFDSISKNTWAPAPDTWAPAP 188
           +SP     S   N++D G    DS S     P+PD+W P P
Sbjct: 459 SSPSPFSSSSPENVEDSG---LDSPSHAAPGPSPDSWVPRP 496


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 29.3 bits (64), Expect = 3.0
 Identities = 18/78 (23%), Positives = 35/78 (44%), Gaps = 1/78 (1%)

Query: 120 GVTQQLSSFETEFNTQPHR-KVEGNFNPFASPQKNRQSDENNLKDPGGSEFDSISKNTWA 178
           G ++++S  E+E    P + K E       SP      D  +L D G S+   I ++  +
Sbjct: 71  GRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRS 130

Query: 179 PAPDTWAPAPDQTEQDQN 196
            +P  ++P   + + D +
Sbjct: 131 TSPSIYSPGSVENDSDSS 148


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 29.3 bits (64), Expect = 3.0
 Identities = 18/78 (23%), Positives = 35/78 (44%), Gaps = 1/78 (1%)

Query: 120 GVTQQLSSFETEFNTQPHR-KVEGNFNPFASPQKNRQSDENNLKDPGGSEFDSISKNTWA 178
           G ++++S  E+E    P + K E       SP      D  +L D G S+   I ++  +
Sbjct: 71  GRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRS 130

Query: 179 PAPDTWAPAPDQTEQDQN 196
            +P  ++P   + + D +
Sbjct: 131 TSPSIYSPGSVENDSDSS 148


>gi|14110378 neighbor of BRCA1 gene 1 [Homo sapiens]
          Length = 966

 Score = 28.9 bits (63), Expect = 3.9
 Identities = 13/36 (36%), Positives = 25/36 (69%), Gaps = 2/36 (5%)

Query: 74  SMSFVEDVTIGEGESIPPDTQFVKTWRIQNS-DVIW 108
           S +FV++  + +G  + P T+F+K WR++N+ +V W
Sbjct: 372 SAAFVDE-NLPDGTHLQPGTKFIKHWRMKNTGNVKW 406


>gi|14110375 neighbor of BRCA1 gene 1 [Homo sapiens]
          Length = 966

 Score = 28.9 bits (63), Expect = 3.9
 Identities = 13/36 (36%), Positives = 25/36 (69%), Gaps = 2/36 (5%)

Query: 74  SMSFVEDVTIGEGESIPPDTQFVKTWRIQNS-DVIW 108
           S +FV++  + +G  + P T+F+K WR++N+ +V W
Sbjct: 372 SAAFVDE-NLPDGTHLQPGTKFIKHWRMKNTGNVKW 406


>gi|14110381 neighbor of BRCA1 gene 1 [Homo sapiens]
          Length = 966

 Score = 28.9 bits (63), Expect = 3.9
 Identities = 13/36 (36%), Positives = 25/36 (69%), Gaps = 2/36 (5%)

Query: 74  SMSFVEDVTIGEGESIPPDTQFVKTWRIQNS-DVIW 108
           S +FV++  + +G  + P T+F+K WR++N+ +V W
Sbjct: 372 SAAFVDE-NLPDGTHLQPGTKFIKHWRMKNTGNVKW 406


>gi|148236531 hypothetical protein LOC339779 [Homo sapiens]
          Length = 412

 Score = 28.5 bits (62), Expect = 5.1
 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 2/77 (2%)

Query: 136 PHRKVEGNFNPFASPQKNRQSDENNLKDPGGSEFDSISKNT-WAPAPDTWAPAPDQTEQD 194
           PH+ +  +  PF+S Q  R S         G +F S   N+ +AP P + +     T   
Sbjct: 40  PHQGLPPSQPPFSSTQSRRPSSPPPASPSPGFQFGSCDSNSDFAPHPYSPSLPSSPTFFH 99

Query: 195 QNRLSQNSVNL-SPSSH 210
           QN LS       SPS+H
Sbjct: 100 QNYLSLPRPRASSPSNH 116


>gi|33188443 microfilament and actin filament cross-linker protein
            isoform b [Homo sapiens]
          Length = 5938

 Score = 28.1 bits (61), Expect = 6.7
 Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 1/63 (1%)

Query: 80   DVTIGEGESIPPDTQFVKTWRIQNSDVIWVILSVEVGGLLGVTQQLSSFETEFNTQPHRK 139
            D+ I   E+     +  K    QN D +   L  + G L  +TQ+L  F+  F     +K
Sbjct: 3407 DILINSSEADEDGIRDEKAGINQNMDAVTEELQAKTGSLEEMTQRLREFQESFK-NIEKK 3465

Query: 140  VEG 142
            VEG
Sbjct: 3466 VEG 3468


>gi|33188445 microfilament and actin filament cross-linker protein
            isoform a [Homo sapiens]
          Length = 5430

 Score = 28.1 bits (61), Expect = 6.7
 Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 1/63 (1%)

Query: 80   DVTIGEGESIPPDTQFVKTWRIQNSDVIWVILSVEVGGLLGVTQQLSSFETEFNTQPHRK 139
            D+ I   E+     +  K    QN D +   L  + G L  +TQ+L  F+  F     +K
Sbjct: 2905 DILINSSEADEDGIRDEKAGINQNMDAVTEELQAKTGSLEEMTQRLREFQESFK-NIEKK 2963

Query: 140  VEG 142
            VEG
Sbjct: 2964 VEG 2966


>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a2 isoform b [Homo sapiens]
          Length = 1572

 Score = 27.7 bits (60), Expect = 8.7
 Identities = 14/58 (24%), Positives = 23/58 (39%)

Query: 152  KNRQSDENNLKDPGGSEFDSISKNTWAPAPDTWAPAPDQTEQDQNRLSQNSVNLSPSS 209
            K R+   N  KDP   + +   K    P  +  +P P +  +  N +    +N   SS
Sbjct: 1344 KKRKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSPNPPKLTKQMNAIIDTVINYKDSS 1401


>gi|54792100 erbB-3 isoform 1 precursor [Homo sapiens]
          Length = 1342

 Score = 27.7 bits (60), Expect = 8.7
 Identities = 15/52 (28%), Positives = 24/52 (46%), Gaps = 9/52 (17%)

Query: 50  MTNWNLQAAIGAYY---------DFESPNISVPSMSFVEDVTIGEGESIPPD 92
           + NW +Q A G YY         +  + N+ + S S V+    G  + +PPD
Sbjct: 811 LLNWGVQIAKGMYYLEEHGMVHRNLAARNVLLKSPSQVQVADFGVADLLPPD 862


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.131    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,148,203
Number of Sequences: 37866
Number of extensions: 478130
Number of successful extensions: 914
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 902
Number of HSP's gapped (non-prelim): 19
length of query: 232
length of database: 18,247,518
effective HSP length: 99
effective length of query: 133
effective length of database: 14,498,784
effective search space: 1928338272
effective search space used: 1928338272
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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