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Search of human proteins with 4557851
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557851 solute carrier family 2 (facilitated glucose
transporter), member 2 [Homo sapiens]
(524 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557851 solute carrier family 2 (facilitated glucose transpor... 1030 0.0
gi|166795299 solute carrier family 2 (facilitated glucose transp... 540 e-153
gi|4507011 glucose transporter 4 [Homo sapiens] 520 e-147
gi|5902090 solute carrier family 2 (facilitated glucose transpor... 501 e-142
gi|23592238 glucose transporter 14 [Homo sapiens] 482 e-136
gi|4507013 solute carrier family 2 (facilitated glucose/fructose... 341 1e-93
gi|134053883 intestinal facilitative glucose transporter 7 [Homo... 317 2e-86
gi|47933389 solute carrier family 2, member 9 protein isoform 2 ... 259 4e-69
gi|47933387 solute carrier family 2, member 9 protein isoform 1 ... 259 4e-69
gi|190684655 glucose transporter protein 10 isoform a [Homo sapi... 253 2e-67
gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens] 253 2e-67
gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens] 253 2e-67
gi|21361449 solute carrier family 2 (facilitated glucose transpo... 180 2e-45
gi|223029432 solute carrier family 2 (facilitated glucose transp... 152 6e-37
gi|203098995 solute carrier family 2 (facilitated glucose transp... 148 1e-35
gi|223029430 solute carrier family 2 (facilitated glucose transp... 140 3e-33
gi|21553331 solute carrier family 2 (facilitated glucose transpo... 124 3e-28
gi|207447703 solute carrier family 2 (facilitated glucose/fructo... 118 1e-26
gi|13540547 solute carrier family 2 member 10 [Homo sapiens] 103 5e-22
gi|24497490 solute carrier family 22 member 4 [Homo sapiens] 59 1e-08
gi|24308167 SV2 related protein [Homo sapiens] 57 3e-08
gi|4507001 solute carrier family 22 member 2 [Homo sapiens] 54 5e-07
gi|166197673 solute carrier family 22, member 15 [Homo sapiens] 51 2e-06
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap... 45 1e-04
gi|8923870 solute carrier family 22 member 11 [Homo sapiens] 45 2e-04
gi|4507005 solute carrier family 22 member 5 [Homo sapiens] 45 2e-04
gi|23510410 solute carrier family 22 member 1 isoform b [Homo sa... 43 8e-04
gi|24497480 solute carrier family 22 member 6 isoform d [Homo sa... 43 8e-04
gi|24497478 solute carrier family 22 member 6 isoform c [Homo sa... 43 8e-04
gi|24497476 solute carrier family 22 member 6 isoform b [Homo sa... 43 8e-04
>gi|4557851 solute carrier family 2 (facilitated glucose
transporter), member 2 [Homo sapiens]
Length = 524
Score = 1030 bits (2664), Expect = 0.0
Identities = 524/524 (100%), Positives = 524/524 (100%)
Query: 1 MTEDKVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYV 60
MTEDKVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYV
Sbjct: 1 MTEDKVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYV 60
Query: 61 INSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGD 120
INSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGD
Sbjct: 61 INSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGD 120
Query: 121 TLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIA 180
TLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIA
Sbjct: 121 TLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIA 180
Query: 181 PTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCP 240
PTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCP
Sbjct: 181 PTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCP 240
Query: 241 ESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSY 300
ESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSY
Sbjct: 241 ESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSY 300
Query: 301 RQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLV 360
RQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLV
Sbjct: 301 RQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLV 360
Query: 361 EKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPW 420
EKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPW
Sbjct: 361 EKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPW 420
Query: 421 FMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFT 480
FMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFT
Sbjct: 421 FMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFT 480
Query: 481 FFKVPETKGKSFEEIAAEFQKKSGSAHRPKAAVEMKFLGATETV 524
FFKVPETKGKSFEEIAAEFQKKSGSAHRPKAAVEMKFLGATETV
Sbjct: 481 FFKVPETKGKSFEEIAAEFQKKSGSAHRPKAAVEMKFLGATETV 524
>gi|166795299 solute carrier family 2 (facilitated glucose
transporter), member 1 [Homo sapiens]
Length = 492
Score = 540 bits (1391), Expect = e-153
Identities = 274/511 (53%), Positives = 364/511 (71%), Gaps = 35/511 (6%)
Query: 5 KVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYVINST 64
K+TG L+ V AVLGS QFGY+ GVINAPQ+VI Y ++ ++ Y
Sbjct: 7 KLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFY---------NQTWVHRY---GE 54
Query: 65 DELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLGR 124
LPT +T LWSLSV+ F+VGGM SF G + GR
Sbjct: 55 SILPT----------------------TLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGR 92
Query: 125 IKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTAL 184
+ML+ N+L+ V A+LMGFSKLG S ++I GR I G+YCGL +G VPMY+GE++PTAL
Sbjct: 93 RNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTAL 152
Query: 185 RGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPR 244
RGALGT HQL IV GILI+Q+ GL+ I+GN DLW +LL + + A+LQ ++L FCPESPR
Sbjct: 153 RGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPR 212
Query: 245 YLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPI 304
+L I +EE +AK LK+LRG DVT D+ EM++E + E+KV+I++LF + +YRQPI
Sbjct: 213 FLLINRNEENRAKSVLKKLRGTADVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPI 272
Query: 305 LVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEKAG 364
L+A++L ++QQ SGIN +FYYSTSIF+ AG+ +PVYATIG G VN FT VS+F+VE+AG
Sbjct: 273 LIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAG 332
Query: 365 RRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVA 424
RR+L LIG++GM CAI M++ L LL + WMSY+S++AIF FV+FFE+GPGPIPWF+VA
Sbjct: 333 RRTLHLIGLAGMAGCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVA 392
Query: 425 EFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFFKV 484
E FSQGPRPAA+A+A FSNWT NFIV +CFQY+ CGPYVF +F +L+ F +FT+FKV
Sbjct: 393 ELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKV 452
Query: 485 PETKGKSFEEIAAEFQKKSGSAHRPKAAVEM 515
PETKG++F+EIA+ F ++ G++ K E+
Sbjct: 453 PETKGRTFDEIASGF-RQGGASQSDKTPEEL 482
>gi|4507011 glucose transporter 4 [Homo sapiens]
Length = 509
Score = 520 bits (1340), Expect = e-147
Identities = 273/521 (52%), Positives = 368/521 (70%), Gaps = 31/521 (5%)
Query: 3 EDKVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYVIN 62
+ +VTGTLV V +AVLGS QFGY+IGVINAPQ+VI Y ++
Sbjct: 17 QQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNET-------------WLGR 63
Query: 63 STDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTL 122
E P S P T +T LW+LSV+ F+VGGM +SF G + L
Sbjct: 64 QGPEGP----SSIPPGT-------------LTTLWALSVAIFSVGGMISSFLIGIISQWL 106
Query: 123 GRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPT 182
GR +AMLV N+L+++G LMG + S+ ++I GR + G Y GL SGLVPMY+GEIAPT
Sbjct: 107 GRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPT 166
Query: 183 ALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPES 242
LRGALGT +QLAIV GILI+Q++GLE +LG LW +LLGL+ + A+LQ +LL FCPES
Sbjct: 167 HLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWPLLLGLTVLPALLQLVLLPFCPES 226
Query: 243 PRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQ 302
PRYLYI + E A++SLKRL G+ DV+ + E++ E+ + E+ +S++QL + ++RQ
Sbjct: 227 PRYLYIIQNLEGPARKSLKRLTGWADVSGVLAELKDEKRKLERERPLSLLQLLGSRTHRQ 286
Query: 303 PILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEK 362
P+++A++L ++QQ SGIN +FYYSTSIF+TAG+ +P YATIG G VN VFT VSV LVE+
Sbjct: 287 PLIIAVVLQLSQQLSGINAVFYYSTSIFETAGVGQPAYATIGAGVVNTVFTLVSVLLVER 346
Query: 363 AGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFM 422
AGRR+L L+G++GM CAI M+V L+LL + MSYVS++AIF FV+FFEIGPGPIPWF+
Sbjct: 347 AGRRTLHLLGLAGMCGCAILMTVALLLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFI 406
Query: 423 VAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFF 482
VAE FSQGPRPAA+A+A FSNWT NFI+ + FQY+A+ GPYVF LFA +LL F +FTF
Sbjct: 407 VAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFL 466
Query: 483 KVPETKGKSFEEIAAEFQKKSGSAHRP-KAAVEMKFLGATE 522
+VPET+G++F++I+A F + + K + E+++LG E
Sbjct: 467 RVPETRGRTFDQISAAFHRTPSLLEQEVKPSTELEYLGPDE 507
>gi|5902090 solute carrier family 2 (facilitated glucose
transporter), member 3 [Homo sapiens]
Length = 496
Score = 501 bits (1289), Expect = e-142
Identities = 257/508 (50%), Positives = 346/508 (68%), Gaps = 34/508 (6%)
Query: 1 MTEDKVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYV 60
M KVT L+F + A +GSFQFGY+ GVINAP+++I ++ IN
Sbjct: 1 MGTQKVTPALIFAITVATIGSFQFGYNTGVINAPEKII--------------KEFINK-- 44
Query: 61 INSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGD 120
T++ N P+ L+T LWSLSV+ F+VGGM SF G +
Sbjct: 45 --------TLTDKGNAPPSE----------VLLTSLWSLSVAIFSVGGMIGSFSVGLFVN 86
Query: 121 TLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIA 180
GR +ML+ N+L++ G MG K+ S ++I GR + GL+CGL +G VPMYIGEI+
Sbjct: 87 RFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEIS 146
Query: 181 PTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCP 240
PTALRGA GT +QL IV GIL++QI GLEFILG+ +LW +LLG + + AILQS L FCP
Sbjct: 147 PTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCP 206
Query: 241 ESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSY 300
ESPR+L I EE AKQ L+RL G DV++DI EM+ E S E++V++++LF SSY
Sbjct: 207 ESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSY 266
Query: 301 RQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLV 360
RQPI+++++L ++QQ SGIN +FYYST IF+ AG+ +P+YATIG G VN +FT VS+FLV
Sbjct: 267 RQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPIYATIGAGVVNTIFTVVSLFLV 326
Query: 361 EKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPW 420
E+AGRR+L +IG+ GM C+ M+V L+L + ++ MS+V + AI +FV+FFEIGPGPIPW
Sbjct: 327 ERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVCIGAILVFVAFFEIGPGPIPW 386
Query: 421 FMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFT 480
F+VAE FSQGPRPAA+A+A SNWT NF+V L F A + G YVF +F G L+ F FT
Sbjct: 387 FIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFT 446
Query: 481 FFKVPETKGKSFEEIAAEFQKKSGSAHR 508
FFKVPET+G++FE+I F+ ++ A R
Sbjct: 447 FFKVPETRGRTFEDITRAFEGQAHGADR 474
>gi|23592238 glucose transporter 14 [Homo sapiens]
Length = 520
Score = 482 bits (1240), Expect = e-136
Identities = 249/503 (49%), Positives = 338/503 (67%), Gaps = 34/503 (6%)
Query: 6 VTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYVINSTD 65
VT L+F + A +GSFQFGY+ GVINAP+ +I ++ IN
Sbjct: 30 VTPALIFAITVATIGSFQFGYNTGVINAPETII--------------KEFINK------- 68
Query: 66 ELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLGRI 125
T++ N P+ L+T LWSLSV+ F+VGGM SF G + GR
Sbjct: 69 ---TLTDKANAPPSE----------VLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRR 115
Query: 126 KAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTALR 185
+ML+ N+L+ G LMG K+ S ++I GR + GL+CGL +G VPMYIGEI+PTALR
Sbjct: 116 NSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALR 175
Query: 186 GALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPRY 245
GA GT +QL IV GIL++QI GLE ILG+ +LW +LLG + + AILQS L CPESPR+
Sbjct: 176 GAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRF 235
Query: 246 LYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPIL 305
L I +E A + L+RL G DV++DI EM+ E S E++V++++LF SSYRQPI+
Sbjct: 236 LLINRKKEENATRILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPII 295
Query: 306 VALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEKAGR 365
++++L ++QQ SGIN +FYYST IF+ AG+ +P+YATI G VN +FT +S+FLVE+AGR
Sbjct: 296 ISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGR 355
Query: 366 RSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAE 425
R+L +IG+ GM C+ M+V L+L N ++ MS+V + AI +FV+ FEIGPGPIPWF+VAE
Sbjct: 356 RTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAE 415
Query: 426 FFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFFKVP 485
FSQGPRPAA+A+A SNWT NF+V L F A + G YVF +F G L+ F FTFFKVP
Sbjct: 416 LFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVP 475
Query: 486 ETKGKSFEEIAAEFQKKSGSAHR 508
ET+G++FE+I F+ ++ A R
Sbjct: 476 ETRGRTFEDITRAFEGQAHGADR 498
>gi|4507013 solute carrier family 2 (facilitated glucose/fructose
transporter), member 5 isoform 1 [Homo sapiens]
Length = 501
Score = 341 bits (874), Expect = 1e-93
Identities = 199/504 (39%), Positives = 281/504 (55%), Gaps = 37/504 (7%)
Query: 1 MTEDKVTGTLVFTVITAVLGS-FQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNY 59
M E ++T L + A GS FQ+GY++ +N+P ++ Y N
Sbjct: 8 MKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFY--------------NET 53
Query: 60 VINSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLG 119
T E M P +T+LWS++VS F GG S G L
Sbjct: 54 YYGRTGEF------MEDFP--------------LTLLWSVTVSMFPFGGFIGSLLVGPLV 93
Query: 120 DTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEI 179
+ GR A+L NI S+V A+LMG S++ S LII R + G+ G+ S +VPMY+GE+
Sbjct: 94 NKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLVGICAGVSSNVVPMYLGEL 153
Query: 180 APTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFC 239
AP LRGALG QL I GIL++QI GL +L N D W ILLGL+GV A LQ LLL F
Sbjct: 154 APKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPILLGLTGVPAALQLLLLPFF 213
Query: 240 PESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSS 299
PESPRYL I+ +E AK++L+ LRG+D V +++ E+R+E E + +S+++LF S
Sbjct: 214 PESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIRQEDEAEKAAGFISVLKLFRMRS 273
Query: 300 YRQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKP--VYATIGVGAVNMVFTAVSV 357
R +L ++L QQ SG+N I+YY+ I+ +AG+ + Y T G GAVN+V T +V
Sbjct: 274 LRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPEEHVQYVTAGTGAVNVVMTFCAV 333
Query: 358 FLVEKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGP 417
F+VE GRR L L+G S + ++ L L + SWM Y+S++ + +V +GP P
Sbjct: 334 FVVELLGRRLLLLLGFSICLIACCVLTAALALQDTVSWMPYISIVCVISYVIGHALGPSP 393
Query: 418 IPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFT 477
IP ++ E F Q RP+A + +W NF V L F +I + GPY F +FA + L T
Sbjct: 394 IPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQEGLGPYSFIVFAVICLLTT 453
Query: 478 LFTFFKVPETKGKSFEEIAAEFQK 501
++ F VPETK K+F EI F K
Sbjct: 454 IYIFLIVPETKAKTFIEINQIFTK 477
>gi|134053883 intestinal facilitative glucose transporter 7 [Homo
sapiens]
Length = 512
Score = 317 bits (811), Expect = 2e-86
Identities = 177/504 (35%), Positives = 275/504 (54%), Gaps = 37/504 (7%)
Query: 3 EDKVTGTLVFTVITAVLGS-FQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYVI 61
E ++ TL+ ++A GS FQ+GY++ V+N P +V S Y
Sbjct: 16 EGRLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNE----------------- 58
Query: 62 NSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDT 121
T + T +L+ +LWS +VS F +GG+ S G L D+
Sbjct: 59 -----------------TYFERHATFMDGKLMLLLWSCTVSMFPLGGLLGSLLVGLLVDS 101
Query: 122 LGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAP 181
GR +L+ NI +++ A+LMG SK+ + LI+ R + G+ G+ +PMY+GE+AP
Sbjct: 102 CGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVVLGVCAGISYSALPMYLGELAP 161
Query: 182 TALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPE 241
LRG +GT ++ ++ G+ ++QI L+ ILGN W +LL L+GV A+LQ L L F PE
Sbjct: 162 KNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPVLLALTGVPALLQLLTLPFFPE 221
Query: 242 SPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYR 301
SPRY I+ +E A+Q+L+RLRG+ D+ ++ +MR E +E +S++ L S R
Sbjct: 222 SPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMRAEARAERAEGHLSVLHLCALRSLR 281
Query: 302 QPILVALMLHVAQQFSGINGIFYYSTSIFQTAGI--SKPVYATIGVGAVNMVFTAVSVFL 359
+L ++L QQ SGIN I YY+ +I+ +AG+ + Y T+G G VN+V T S L
Sbjct: 282 WQLLSIIVLMAGQQLSGINAINYYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVL 341
Query: 360 VEKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIP 419
VE+ GRR L L G + ++V L+ N+ +SY+ +I +F +++ IGP P+P
Sbjct: 342 VERLGRRHLLLAGYGICGSACLVLTVVLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVP 401
Query: 420 WFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLF 479
+ E F Q R AA + +W NFI+ F I + G Y F +FAG+ L ++
Sbjct: 402 SVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFPSIQEAIGAYSFIIFAGICLLTAIY 461
Query: 480 TFFKVPETKGKSFEEIAAEFQKKS 503
+ +PETKGK+F EI F K++
Sbjct: 462 IYVVIPETKGKTFVEINRIFAKRN 485
>gi|47933389 solute carrier family 2, member 9 protein isoform 2
[Homo sapiens]
Length = 511
Score = 259 bits (662), Expect = 4e-69
Identities = 157/513 (30%), Positives = 257/513 (50%), Gaps = 49/513 (9%)
Query: 10 LVFTVITAVLGSFQFGYDIGVINAPQQVIISHY------RHVLGVPLDDRKAINNYVINS 63
LV ++ A SF +GY++ V+NAP I + Y RH G P+D
Sbjct: 28 LVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRH--GRPIDP----------- 74
Query: 64 TDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLG 123
+T+LWS++VS FA+GG+ + +G LG
Sbjct: 75 ---------------------------DTLTLLWSVTVSIFAIGGLVGTLIVKMIGKVLG 107
Query: 124 RIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTA 183
R +L N ++ ALLM S + ++I GR I G+ G+ ++PMY+ EI+P
Sbjct: 108 RKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKE 167
Query: 184 LRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESP 243
+RG+LG + I G+ Q++GL +LG W L G+ V A++Q L L F P+SP
Sbjct: 168 IRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSP 227
Query: 244 RYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQP 303
RYL ++ E +A ++ + G DV++++ E+ E S + VS+++L R
Sbjct: 228 RYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQRSIRLVSVLELLRAPYVRWQ 287
Query: 304 ILVALMLHVAQQFSGINGIFYYSTSIFQTAGI--SKPVYATIGVGAVNMVFTAVSVFLVE 361
++ ++ Q G+N I++Y+ SIF AGI +K Y T+ G + + S ++E
Sbjct: 288 VVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYVTLSTGGIETLAAVFSGLVIE 347
Query: 362 KAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWF 421
GRR L + G M + +++ L L + W+ Y+S++ I ++ F GPG IP+
Sbjct: 348 HLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFI 407
Query: 422 MVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTF 481
+ EFF Q RPAA IA NW NF V L F +I Y F +FA + + ++ +
Sbjct: 408 LTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSLDTYCFLVFATICITGAIYLY 467
Query: 482 FKVPETKGKSFEEIAAEFQKKSGSAHRPKAAVE 514
F +PETK +++ EI+ F K++ A+ P+ ++
Sbjct: 468 FVLPETKNRTYAEISQAFSKRN-KAYPPEEKID 499
>gi|47933387 solute carrier family 2, member 9 protein isoform 1
[Homo sapiens]
Length = 540
Score = 259 bits (662), Expect = 4e-69
Identities = 157/513 (30%), Positives = 257/513 (50%), Gaps = 49/513 (9%)
Query: 10 LVFTVITAVLGSFQFGYDIGVINAPQQVIISHY------RHVLGVPLDDRKAINNYVINS 63
LV ++ A SF +GY++ V+NAP I + Y RH G P+D
Sbjct: 57 LVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRH--GRPIDP----------- 103
Query: 64 TDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLG 123
+T+LWS++VS FA+GG+ + +G LG
Sbjct: 104 ---------------------------DTLTLLWSVTVSIFAIGGLVGTLIVKMIGKVLG 136
Query: 124 RIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTA 183
R +L N ++ ALLM S + ++I GR I G+ G+ ++PMY+ EI+P
Sbjct: 137 RKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKE 196
Query: 184 LRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESP 243
+RG+LG + I G+ Q++GL +LG W L G+ V A++Q L L F P+SP
Sbjct: 197 IRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSP 256
Query: 244 RYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQP 303
RYL ++ E +A ++ + G DV++++ E+ E S + VS+++L R
Sbjct: 257 RYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQRSIRLVSVLELLRAPYVRWQ 316
Query: 304 ILVALMLHVAQQFSGINGIFYYSTSIFQTAGI--SKPVYATIGVGAVNMVFTAVSVFLVE 361
++ ++ Q G+N I++Y+ SIF AGI +K Y T+ G + + S ++E
Sbjct: 317 VVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYVTLSTGGIETLAAVFSGLVIE 376
Query: 362 KAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWF 421
GRR L + G M + +++ L L + W+ Y+S++ I ++ F GPG IP+
Sbjct: 377 HLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFI 436
Query: 422 MVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTF 481
+ EFF Q RPAA IA NW NF V L F +I Y F +FA + + ++ +
Sbjct: 437 LTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSLDTYCFLVFATICITGAIYLY 496
Query: 482 FKVPETKGKSFEEIAAEFQKKSGSAHRPKAAVE 514
F +PETK +++ EI+ F K++ A+ P+ ++
Sbjct: 497 FVLPETKNRTYAEISQAFSKRN-KAYPPEEKID 528
>gi|190684655 glucose transporter protein 10 isoform a [Homo
sapiens]
Length = 503
Score = 253 bits (647), Expect = 2e-67
Identities = 157/499 (31%), Positives = 249/499 (49%), Gaps = 45/499 (9%)
Query: 10 LVFTVITAVLG-SFQFGYDIGVINAP----QQVIISHYRHVLGVPLDDRKAINNYVINST 64
L+ T+ A +G +FQFGY++ +INAP Q+ ++ G PL D
Sbjct: 20 LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDH----------- 68
Query: 65 DELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLGR 124
L+ ++WSL VS + +GG+ + G L TLGR
Sbjct: 69 ---------------------------LVLLMWSLIVSLYPLGGLFGALLAGPLAITLGR 101
Query: 125 IKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTAL 184
K++LV NI + A+L GFS+ S +I+ GR + G+ G+ + PMY+GE AP L
Sbjct: 102 KKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKEL 161
Query: 185 RGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPR 244
RGA+ + GI++ Q++GL +LG W +LL V LQ L PESPR
Sbjct: 162 RGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPR 221
Query: 245 YLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPI 304
YL I + +L+RLRG D+ ++ E+ +ER + +LF + + R+ +
Sbjct: 222 YLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAACQGCRARRPWELFQHRALRRQV 281
Query: 305 LVALMLHVAQQFSGINGIFYYSTSIFQTAGI--SKPVYATIGVGAVNMVFTAVSVFLVEK 362
++L A + G + ++ Y++S+F+ AG+ +K YA IG G+ ++ VS ++E+
Sbjct: 282 TSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIER 341
Query: 363 AGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFM 422
GRR L + G S M +V L L + F W Y++M IF F+ F IGP + +
Sbjct: 342 VGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGIL 401
Query: 423 VAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFF 482
E F Q RPAA + W +V L F +I + +++ F GV + ++T
Sbjct: 402 ATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGL 461
Query: 483 KVPETKGKSFEEIAAEFQK 501
+PETKGK+F+EI+ E +
Sbjct: 462 FLPETKGKTFQEISKELHR 480
>gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]
Length = 496
Score = 253 bits (647), Expect = 2e-67
Identities = 157/499 (31%), Positives = 249/499 (49%), Gaps = 45/499 (9%)
Query: 10 LVFTVITAVLG-SFQFGYDIGVINAP----QQVIISHYRHVLGVPLDDRKAINNYVINST 64
L+ T+ A +G +FQFGY++ +INAP Q+ ++ G PL D
Sbjct: 13 LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDH----------- 61
Query: 65 DELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLGR 124
L+ ++WSL VS + +GG+ + G L TLGR
Sbjct: 62 ---------------------------LVLLMWSLIVSLYPLGGLFGALLAGPLAITLGR 94
Query: 125 IKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTAL 184
K++LV NI + A+L GFS+ S +I+ GR + G+ G+ + PMY+GE AP L
Sbjct: 95 KKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKEL 154
Query: 185 RGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPR 244
RGA+ + GI++ Q++GL +LG W +LL V LQ L PESPR
Sbjct: 155 RGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPR 214
Query: 245 YLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPI 304
YL I + +L+RLRG D+ ++ E+ +ER + +LF + + R+ +
Sbjct: 215 YLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAACQGCRARRPWELFQHRALRRQV 274
Query: 305 LVALMLHVAQQFSGINGIFYYSTSIFQTAGI--SKPVYATIGVGAVNMVFTAVSVFLVEK 362
++L A + G + ++ Y++S+F+ AG+ +K YA IG G+ ++ VS ++E+
Sbjct: 275 TSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIER 334
Query: 363 AGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFM 422
GRR L + G S M +V L L + F W Y++M IF F+ F IGP + +
Sbjct: 335 VGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGIL 394
Query: 423 VAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFF 482
E F Q RPAA + W +V L F +I + +++ F GV + ++T
Sbjct: 395 ATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGL 454
Query: 483 KVPETKGKSFEEIAAEFQK 501
+PETKGK+F+EI+ E +
Sbjct: 455 FLPETKGKTFQEISKELHR 473
>gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]
Length = 499
Score = 253 bits (647), Expect = 2e-67
Identities = 157/499 (31%), Positives = 249/499 (49%), Gaps = 45/499 (9%)
Query: 10 LVFTVITAVLG-SFQFGYDIGVINAP----QQVIISHYRHVLGVPLDDRKAINNYVINST 64
L+ T+ A +G +FQFGY++ +INAP Q+ ++ G PL D
Sbjct: 16 LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDH----------- 64
Query: 65 DELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLGR 124
L+ ++WSL VS + +GG+ + G L TLGR
Sbjct: 65 ---------------------------LVLLMWSLIVSLYPLGGLFGALLAGPLAITLGR 97
Query: 125 IKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTAL 184
K++LV NI + A+L GFS+ S +I+ GR + G+ G+ + PMY+GE AP L
Sbjct: 98 KKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKEL 157
Query: 185 RGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPR 244
RGA+ + GI++ Q++GL +LG W +LL V LQ L PESPR
Sbjct: 158 RGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPR 217
Query: 245 YLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPI 304
YL I + +L+RLRG D+ ++ E+ +ER + +LF + + R+ +
Sbjct: 218 YLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAACQGCRARRPWELFQHRALRRQV 277
Query: 305 LVALMLHVAQQFSGINGIFYYSTSIFQTAGI--SKPVYATIGVGAVNMVFTAVSVFLVEK 362
++L A + G + ++ Y++S+F+ AG+ +K YA IG G+ ++ VS ++E+
Sbjct: 278 TSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIER 337
Query: 363 AGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFM 422
GRR L + G S M +V L L + F W Y++M IF F+ F IGP + +
Sbjct: 338 VGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGIL 397
Query: 423 VAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFF 482
E F Q RPAA + W +V L F +I + +++ F GV + ++T
Sbjct: 398 ATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGL 457
Query: 483 KVPETKGKSFEEIAAEFQK 501
+PETKGK+F+EI+ E +
Sbjct: 458 FLPETKGKTFQEISKELHR 476
>gi|21361449 solute carrier family 2 (facilitated glucose
transporter), member 8 [Homo sapiens]
Length = 477
Score = 180 bits (457), Expect = 2e-45
Identities = 124/417 (29%), Positives = 209/417 (50%), Gaps = 41/417 (9%)
Query: 106 VGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYC 165
+G GGWL D GR ++L+ ++ + G ++ ++ +++ GR ++GL C
Sbjct: 78 LGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQ---DVWMLLGGRLLTGLAC 134
Query: 166 GLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLS 225
G+ S + P+YI EIA A+RG LG+ QL +V GIL++ + G ++L W L L
Sbjct: 135 GVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAG--WVLE----WRWLAVLG 188
Query: 226 GVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASS 285
V L LL+ F PE+PR+L + + +A +L+ L G +E E +
Sbjct: 189 CVPPSLMLLLMCFMPETPRFLLTQHRRQ-EAMAALRFLWG--------SEQGWEDPPIGA 239
Query: 286 EQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGV 345
EQ + L Y+ P ++ + L QQ SG+N + +Y+ +IF+ A A++ V
Sbjct: 240 EQSFHLALLRQPGIYK-PFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVV 298
Query: 346 GAVNMVFTAVSVFLVEKAGRRSLFLI---------------------GMSGMFVCAIFMS 384
G + ++FTAV+ ++++AGRR L ++ G AI
Sbjct: 299 GVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAP 358
Query: 385 VGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNW 444
V ++ ++++++ ++ LF++ F +G GPIPW +++E F + A I +NW
Sbjct: 359 VSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNW 418
Query: 445 TCNFIVALCFQYIADFCGPYVFFLFAGVLLAFT-LFTFFKVPETKGKSFEEIAAEFQ 500
F+V F + + PY F A F+ LFT F VPETKGK+ E+I A F+
Sbjct: 419 LMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFE 475
>gi|223029432 solute carrier family 2 (facilitated glucose
transporter), member 6 isoform 1 [Homo sapiens]
Length = 507
Score = 152 bits (385), Expect = 6e-37
Identities = 130/427 (30%), Positives = 204/427 (47%), Gaps = 51/427 (11%)
Query: 105 AVGGMTASFFGGWLGDTLGRIKAMLVANILSLVG-ALLMGFSKLGPSHILIIAGRSISGL 163
A GG++A L D LGR +++ + + S G AL+ G L +++ GR+++G
Sbjct: 93 AAGGLSAMI----LNDLLGRKLSIMFSAVPSAAGYALMAGAHGLW----MLLLGRTLTGF 144
Query: 164 YCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLG 223
GL + +P+Y+ EIAP +RGALG QL V G L +GL W L
Sbjct: 145 AGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLL------PWRWLAV 198
Query: 224 LSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYD-DVTKDINEMRKEREE 282
++ LLL F P SPR+L + +E +A ++L LRG D DV + +++
Sbjct: 199 AGEAPVLIMILLLSFMPNSPRFLLSRGRDE-EALRALAWLRGTDVDVHWEFEQIQDNVRR 257
Query: 283 ASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIF-QTAGISKPVYA 341
SS +VS + R PI VAL++ + QQ +GI I Y SIF TA + P
Sbjct: 258 QSS--RVSWAEARAPHVCR-PITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDD 314
Query: 342 TIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLVL------------ 389
VGAV ++ ++ ++ AGR+ L + + MF A +++GL +
Sbjct: 315 AAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMF--AANLTLGLYIHFGPRPLSPNST 372
Query: 390 --LNKFSW-------------MSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPA 434
L SW ++ V ++A LF+ + +G GPI W +++E R
Sbjct: 373 AGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGV 432
Query: 435 ALAIAAFSNWTCNFIVALCFQYIADFCGPYV-FFLFAGVLLAFTLFTFFKVPETKGKSFE 493
A + ++W F++ F + G V FF FA + L +FT VPETKG+S E
Sbjct: 433 ASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLE 492
Query: 494 EIAAEFQ 500
+I + F+
Sbjct: 493 QIESFFR 499
>gi|203098995 solute carrier family 2 (facilitated glucose
transporter), member 13 [Homo sapiens]
Length = 648
Score = 148 bits (373), Expect = 1e-35
Identities = 100/302 (33%), Positives = 157/302 (51%), Gaps = 13/302 (4%)
Query: 96 LWS-LSVSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILI 154
LW L VSS ++ GG L GR A+L+A+ L G+ ++ + + +
Sbjct: 118 LWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAAN---NKETL 174
Query: 155 IAGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGN 214
+AGR + GL G+ S VP+YI E++P LRG L T + L I G + ++ F
Sbjct: 175 LAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQ 234
Query: 215 YDLWHILLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDI- 273
D W +LGL+ V A++Q F PESPR+L I+ + KA++ L ++RG + ++
Sbjct: 235 KDGWRYMLGLAAVPAVIQFFGFLFLPESPRWL-IQKGQTQKARRILSQMRGNQTIDEEYD 293
Query: 274 ---NEMRKEREEASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIF 330
N + +E +E S V I ++ + R+ ++V L + QQ SGIN I YYS +I
Sbjct: 294 SIKNNIEEEEKEVGSAGPV-ICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATIL 352
Query: 331 QTAGISK---PVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGL 387
Q +G+ ++ N +FT V V+LVEK GRR L ++G V I +++G
Sbjct: 353 QMSGVEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGF 412
Query: 388 VL 389
VL
Sbjct: 413 VL 414
Score = 72.4 bits (176), Expect = 9e-13
Identities = 37/107 (34%), Positives = 60/107 (56%), Gaps = 1/107 (0%)
Query: 397 SYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQY 456
S+ +++ + L++ FF G GP+PW + +E + R A ++ NW N +V+L F +
Sbjct: 506 SWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLH 565
Query: 457 IADFCGPY-VFFLFAGVLLAFTLFTFFKVPETKGKSFEEIAAEFQKK 502
A++ Y FFL+AG LF + +PETKGK EEI + F +
Sbjct: 566 TAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNR 612
>gi|223029430 solute carrier family 2 (facilitated glucose
transporter), member 6 isoform 2 [Homo sapiens]
Length = 445
Score = 140 bits (353), Expect = 3e-33
Identities = 121/400 (30%), Positives = 185/400 (46%), Gaps = 59/400 (14%)
Query: 105 AVGGMTASFFGGWLGDTLGRIKAMLVANILSLVG-ALLMGFSKLGPSHILIIAGRSISGL 163
A GG++A L D LGR +++ + + S G AL+ G L +++ GR+++G
Sbjct: 93 AAGGLSAMI----LNDLLGRKLSIMFSAVPSAAGYALMAGAHGLW----MLLLGRTLTGF 144
Query: 164 YCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLG 223
GL + +P+Y+ EIAP +RGALG QL V G L +GL W L
Sbjct: 145 AGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP------WRWLAV 198
Query: 224 LSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYD-DVTKDINEMRKEREE 282
++ LLL F P SPR+L + +E +A ++L LRG D DV + +++
Sbjct: 199 AGEAPVLIMILLLSFMPNSPRFLLSRGRDE-EALRALAWLRGTDVDVHWEFEQIQDNVRR 257
Query: 283 ASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIFQ-TAGISKPVYA 341
SS +VS + R PI VAL++ + QQ +GI I Y SIF TA + P
Sbjct: 258 QSS--RVSWAEARAPHVCR-PITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDD 314
Query: 342 TIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSM 401
VGAV ++ ++ ++ AGR+
Sbjct: 315 AAIVGAVRLLSVLIAALTMDLAGRK----------------------------------- 339
Query: 402 IAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFC 461
+ LFVS + +G GPI W +++E R A + ++W F++ F +
Sbjct: 340 --VLLFVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTF 397
Query: 462 GPYV-FFLFAGVLLAFTLFTFFKVPETKGKSFEEIAAEFQ 500
G V FF FA + L +FT VPETKG+S E+I + F+
Sbjct: 398 GLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFFR 437
>gi|21553331 solute carrier family 2 (facilitated glucose
transporter), member 12 [Homo sapiens]
Length = 617
Score = 124 bits (310), Expect = 3e-28
Identities = 92/295 (31%), Positives = 155/295 (52%), Gaps = 14/295 (4%)
Query: 101 VSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSI 160
VSS +G + AS GG L D GR A+++++ L +G+L++ S S+ ++I GR
Sbjct: 83 VSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSL---SYTVLIVGRIA 139
Query: 161 SGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHI 220
G+ L S +YI EIAP RG L + ++L IV GIL + I F + W
Sbjct: 140 IGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAF-ANVFHGWKY 198
Query: 221 LLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKER 280
+ GL +LQ++ ++F P SPR+L +K +E A + L RLR D T+++ ++
Sbjct: 199 MFGLVIPLGVLQAIAMYFLPPSPRFLVMK-GQEGAASKVLGRLRALSDTTEELTVIKSSL 257
Query: 281 EEASSEQKVSIIQLF-TNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPV 339
++ E + S LF + + R I++ L L Q +G I +Y++++ ++ G
Sbjct: 258 KD---EYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNE 314
Query: 340 YATI---GVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLVLLN 391
A++ GVG V ++ T + LV+ G ++ IG S M A +++G+V LN
Sbjct: 315 AASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVM--AASLVTMGIVNLN 367
Score = 84.0 bits (206), Expect = 3e-16
Identities = 39/109 (35%), Positives = 68/109 (62%), Gaps = 1/109 (0%)
Query: 394 SWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALC 453
+++ ++S+ ++ ++V+ F IG GP+PW +++E F G R A+A+ + NW N +++L
Sbjct: 458 AFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLT 517
Query: 454 FQYIADFCG-PYVFFLFAGVLLAFTLFTFFKVPETKGKSFEEIAAEFQK 501
F + D G P+V F++ + LA LF +PETKG S E+I+ E K
Sbjct: 518 FLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQISMELAK 566
>gi|207447703 solute carrier family 2 (facilitated glucose/fructose
transporter), member 5 isoform 2 [Homo sapiens]
Length = 244
Score = 118 bits (296), Expect = 1e-26
Identities = 79/217 (36%), Positives = 108/217 (49%), Gaps = 35/217 (16%)
Query: 1 MTEDKVTGTLVFTVITAVLGS-FQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNY 59
M E ++T L + A GS FQ+GY++ +N+P ++ Y N
Sbjct: 8 MKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFY--------------NET 53
Query: 60 VINSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLG 119
T E M P +T+LWS++VS F GG S G L
Sbjct: 54 YYGRTGEF------MEDFP--------------LTLLWSVTVSMFPFGGFIGSLLVGPLV 93
Query: 120 DTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEI 179
+ GR A+L NI S+V A+LMG S++ S LII R + G+ G+ S +VPMY+GE+
Sbjct: 94 NKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLVGICAGVSSNVVPMYLGEL 153
Query: 180 APTALRGALGTFHQLAIVTGILISQIIGLEFILGNYD 216
AP LRGALG QL I GIL++QI GL +L N D
Sbjct: 154 APKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVD 190
>gi|13540547 solute carrier family 2 member 10 [Homo sapiens]
Length = 541
Score = 103 bits (256), Expect = 5e-22
Identities = 85/292 (29%), Positives = 138/292 (47%), Gaps = 29/292 (9%)
Query: 101 VSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSI 160
V S +G + AS GG+L D GR +A+L +N++ L G+L +G L S ++ GR++
Sbjct: 51 VGSLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLG---LAGSLAWLVLGRAV 107
Query: 161 SGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHI 220
G L S +Y+ E+ RG L + ++ I GIL+S + + G W
Sbjct: 108 VGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYA-LAGTPWGWRH 166
Query: 221 LLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKER 280
+ G + A+LQSL L F P +E + L L+G +
Sbjct: 167 MFGWATAPAVLQSLSLLFLPAGT--------DETATHKDLIPLQGGE-----------AP 207
Query: 281 EEASSEQKVSIIQLF-TNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGI---S 336
+ + S + LF + R V L L + QQ +G + Y+++IF + G S
Sbjct: 208 KLGPGRPRYSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGS 267
Query: 337 KPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLV 388
V A++G+GAV + T ++ LV++AGRR+L L G + M + +GLV
Sbjct: 268 SAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMALSV--SGIGLV 317
Score = 65.5 bits (158), Expect = 1e-10
Identities = 35/108 (32%), Positives = 55/108 (50%), Gaps = 1/108 (0%)
Query: 396 MSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQ 455
+ + +++ + +FVS F G GP+ W +++E + R A A NW N ++L F
Sbjct: 408 LRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFL 467
Query: 456 YIADFCGPYVFFLFAGVLLAFTL-FTFFKVPETKGKSFEEIAAEFQKK 502
+ G FL G+ L F + VPETKG+S EI +FQK+
Sbjct: 468 DLIGTIGLSWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQKR 515
>gi|24497490 solute carrier family 22 member 4 [Homo sapiens]
Length = 551
Score = 58.5 bits (140), Expect = 1e-08
Identities = 103/448 (22%), Positives = 174/448 (38%), Gaps = 82/448 (18%)
Query: 99 LSVSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGR 158
L+ S F VG + SF G L D GR N+L A+ GFS L I I+
Sbjct: 144 LTTSLFFVGVLLGSFVSGQLSDRFGR------KNVLFATMAVQTGFSFL---QIFSISWE 194
Query: 159 SISGLYC----GLISGLVPMYI--GEIAPTALRGALGTFHQLAIVTGILISQIIGLEFIL 212
+ L+ G IS V +I EI ++R T L + T + ++ F
Sbjct: 195 MFTVLFVIVGMGQISNYVVAFILGTEILGKSVRIIFST---LGVCTFFAVGYMLLPLFAY 251
Query: 213 GNYDLWHILLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKD 272
D W +LL V +L L +F PESPR+L S +R R +D+ +
Sbjct: 252 FIRD-WRMLLLALTVPGVLCVPLWWFIPESPRWLI-----------SQRRFREAEDIIQK 299
Query: 273 INEMRK-----------EREEASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGING 321
+M E +QK I+ LF + +++L+L + +
Sbjct: 300 AAKMNNIAVPAVIFDSVEELNPLKQQKAFILDLFRTRNIAIMTIMSLLLWM------LTS 353
Query: 322 IFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEKAGRRS------LFLIGMSG 375
+ Y++ S+ + Y + A+ + ++ +L+ + R LF G
Sbjct: 354 VGYFALSL-DAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYIIAAVLFWGGGVL 412
Query: 376 MFVCAI-----FMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQG 430
+F+ + F+S+GLV+L KF S SM+ +F AE +
Sbjct: 413 LFIQLVPVDYYFLSIGLVMLGKFGITSAFSMLYVF-----------------TAELYPTL 455
Query: 431 PRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFFKVPETKGK 490
R A+ + + ++ I+A F Y+ + + + + + + T F PE+ G
Sbjct: 456 VRNMAVGVTSTAS-RVGSIIAPYFVYLGAYNRMLPYIVMGSLTVLIGILTLF-FPESLGM 513
Query: 491 SFEEIAAEFQK----KSGSAHRPKAAVE 514
+ E + QK +SG R E
Sbjct: 514 TLPETLEQMQKVKWFRSGKKTRDSMETE 541
>gi|24308167 SV2 related protein [Homo sapiens]
Length = 548
Score = 57.4 bits (137), Expect = 3e-08
Identities = 98/428 (22%), Positives = 179/428 (41%), Gaps = 62/428 (14%)
Query: 98 SLSVSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAG 157
+L S VG M++S G + D GR + ++ + +L +L F+ P + I+
Sbjct: 123 ALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFA---PVYSWILVL 179
Query: 158 RSISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDL 217
R + G G + V +Y E P R ++ G + ++ + F++ +
Sbjct: 180 RGLVGFGIGGVPQSVTLY-AEFLPMKARAKCILLIEVFWAIGTVFEVVLAV-FVMPSLG- 236
Query: 218 WHILLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMR 277
W LL LS V +L ++L F+ PES RY + ++E KA +LKR+ + + ++
Sbjct: 237 WRWLLILSAVPLLLFAVLCFWLPESARYDVLSGNQE-KAIATLKRIATENGAPMPLGKLI 295
Query: 278 KEREEASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIFQ---TAG 334
R+E + + LFT +R L+ + + FS G+ +T +FQ G
Sbjct: 296 ISRQEDRGKMR----DLFT-PHFRWTTLLLWFIWFSNAFS-YYGLVLLTTELFQAGDVCG 349
Query: 335 IS---KPVYATIGVGA--------VNMVFTAVSVF--------LVEKAGRRSLFLIGMSG 375
IS K V A + +++++T +S F ++++ GR+ +
Sbjct: 350 ISSRKKAVEAKCSLACEYLSEEDYMDLLWTTLSEFPGVLVTLWIIDRLGRKKTMALCFVI 409
Query: 376 MFVCA--IFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRP 433
C+ +F+ VG +++ + LF++ I G F A ++ P
Sbjct: 410 FSFCSLLLFICVGR------------NVLTLLLFIARAFISGG----FQAAYVYT--PEV 451
Query: 434 AALAIAAFSNWTCNFIV---ALCFQYIADFCGPYVFFL----FAGVLLAFTLFTFFKVPE 486
A A TC+ + AL +IA +L ++G L L + F E
Sbjct: 452 YPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAALASCFLPIE 511
Query: 487 TKGKSFEE 494
TKG+ +E
Sbjct: 512 TKGRGLQE 519
>gi|4507001 solute carrier family 22 member 2 [Homo sapiens]
Length = 555
Score = 53.5 bits (127), Expect = 5e-07
Identities = 88/355 (24%), Positives = 152/355 (42%), Gaps = 44/355 (12%)
Query: 97 WSLSV--SSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILI 154
W L + SS VG S G++ D GR +L +++ +LM S P++ +
Sbjct: 147 WMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMAIS---PTYTWM 203
Query: 155 IAGRSISGLY--CGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFIL 212
+ R I GL G + G + I E R +G F+Q+A G+L+ + G+ + L
Sbjct: 204 LIFRLIQGLVSKAGWLIGYI--LITEFVGRRYRRTVGIFYQVAYTVGLLV--LAGVAYAL 259
Query: 213 GNYDLWHILLGLSGVRAILQSLLLFFC-PESPRYLY--------IKLDEEVKAKQ----- 258
++ + L LL ++C PESPR+L +++ + + K
Sbjct: 260 PHWRWLQFTVALPN----FFFLLYYWCIPESPRWLISQNKNAEAMRIIKHIAKKNGKSLP 315
Query: 259 -SLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQL---FTNSSYRQPILVALMLHVAQ 314
SL+RLR ++ K +N + +K ++I + FT+S Q L++H+
Sbjct: 316 ASLQRLRLEEETGKKLNPSFLDLVRTPQIRKHTMILMYNWFTSSVLYQ----GLIMHMGL 371
Query: 315 QFSGINGIFYYSTSI-FQTAGISKPVYATIG----VGAVNMVFTAVSVFLVEKAGRRSLF 369
I F+YS + F A + IG A NMV A + V G
Sbjct: 372 AGDNIYLDFFYSALVEFPAAFMIILTIDRIGRRYPWAASNMVAGAACLASVFIPGDLQWL 431
Query: 370 LIGMSGMFVCAIFMSVGLV-LLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMV 423
I +S + I M+ +V L+N + +++ + + + S +IG G I F+V
Sbjct: 432 KIIISCLGRMGITMAYEIVCLVNAELYPTFIRNLGVHICSSMCDIG-GIITPFLV 485
>gi|166197673 solute carrier family 22, member 15 [Homo sapiens]
Length = 547
Score = 51.2 bits (121), Expect = 2e-06
Identities = 45/149 (30%), Positives = 66/149 (44%), Gaps = 9/149 (6%)
Query: 100 SVSSFAVGGMTASFFG-GWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGR 158
+ SSF G+ G L D GR K L L ++ A+ GFS PS+ R
Sbjct: 113 AASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAIANGFS---PSYEFFAVTR 169
Query: 159 SISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLW 218
+ G+ G +S + + + E TA G+ L GI ++G + + ++
Sbjct: 170 FLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGIAQYALLG--YFIRSWRTL 227
Query: 219 HILLGLSGVRAILQSLLLFFCPESPRYLY 247
IL+ L G L SL F PESPR+LY
Sbjct: 228 AILVNLQGTVVFLLSL---FIPESPRWLY 253
>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
sapiens]
Length = 554
Score = 45.4 bits (106), Expect = 1e-04
Identities = 81/359 (22%), Positives = 145/359 (40%), Gaps = 52/359 (14%)
Query: 97 WSLSV--SSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILI 154
W L + S G + S G+ D GR +L +++ V +LM FS P+++ +
Sbjct: 146 WKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFS---PNYMSM 202
Query: 155 IAGRSISGLYC--GLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFIL 212
+ R + GL ++G I E + R + +Q+A G++ + GL + L
Sbjct: 203 LLFRLLQGLVSKGNWMAGYT--LITEFVGSGSRRTVAIMYQMAFTVGLV--ALTGLAYAL 258
Query: 213 GNYDLWHILLGLSGVRAILQSLLLFFC-PESPRYLY--------IKLDEEVKAKQ----- 258
++ + + L LL ++C PESPR+L IK+ + + K
Sbjct: 259 PHWRWLQLAVSL----PTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPP 314
Query: 259 -SLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQL---FTNSSYRQPILVALMLHVAQ 314
LK L +DVT+ ++ + +K + I + FT+S Q L+LH+
Sbjct: 315 ADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVLYQ----GLILHMGA 370
Query: 315 QFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMS 374
+ F YS + I A I + V ++ L+ A + I
Sbjct: 371 TSGNLYLDFLYSALV----EIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFISPD 426
Query: 375 GMFVCAIFMSVG----------LVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMV 423
++ I M VG + L+N + ++V + + + S +IG G I F+V
Sbjct: 427 LHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIG-GIITPFIV 484
>gi|8923870 solute carrier family 22 member 11 [Homo sapiens]
Length = 550
Score = 45.1 bits (105), Expect = 2e-04
Identities = 69/282 (24%), Positives = 124/282 (43%), Gaps = 33/282 (11%)
Query: 99 LSVSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKL-GPSHIL---- 153
LS S F G + SF G L GR K ML L L A G S + P+ ++
Sbjct: 144 LSQSIFMSGILVGSFIWGLLSYRFGR-KPMLSWCCLQLAVA---GTSTIFAPTFVIYCGL 199
Query: 154 -IIAGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFIL 212
+A ++G++ ++ +V E T+ R T A G + + GL F L
Sbjct: 200 RFVAAFGMAGIFLSSLTLMV-----EWTTTSRRAVTMTVVGCAFSAGQ--AALGGLAFAL 252
Query: 213 GNYDLWHILLGLSGVRAILQSLLLFFCPESPRYLYI--KLDEEVKAKQSLKRLRGYDD-- 268
+ W L + V SL+ ++ PES R+L I K D+ ++ + + R+ G+ +
Sbjct: 253 RD---WRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVARINGHKEAK 309
Query: 269 -VTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIFYYST 327
+T ++ + E AS+++ S++ LF R L+++ + S YY
Sbjct: 310 NLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLIS------YYGL 363
Query: 328 SIFQTAGISKPVYATIGV-GAVNMVFTAVSVFLVEKAGRRSL 368
+F + + ++ + GAV+ + A + L+ GRR++
Sbjct: 364 -VFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTI 404
>gi|4507005 solute carrier family 22 member 5 [Homo sapiens]
Length = 557
Score = 45.1 bits (105), Expect = 2e-04
Identities = 82/422 (19%), Positives = 167/422 (39%), Gaps = 44/422 (10%)
Query: 99 LSVSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGR 158
L++S F VG + SF G L D GR + V + + L FSK +++
Sbjct: 144 LTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSKNFEMFVVLFV-- 201
Query: 159 SISGLYCGLISGLVPMYI--GEIAPTALRGALGTFHQLAIVTGILISQIIGLEFI-LGNY 215
+ G+ G IS V ++ EI ++R T G+ I G + L Y
Sbjct: 202 -LVGM--GQISNYVAAFVLGTEILGKSVRIIFSTL-------GVCIFYAFGYMVLPLFAY 251
Query: 216 DL--WHILLGLSGVRAILQSLLLFFCPESPRYLYI--KLDEEVKAKQSLKRLRGYDDVTK 271
+ W +LL + +L L +F PESPR+L + +E + + G +
Sbjct: 252 FIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKANGIVVPST 311
Query: 272 DINEMRKEREEASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIFQ 331
+ + + +Q +I+ L + R ++++ML + G G+ + ++
Sbjct: 312 IFDPSELQDLSSKKQQSHNILDLLRTWNIRMVTIMSIMLWMTISV-GYFGLSLDTPNLHG 370
Query: 332 TAGISKPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAI-----FMSVG 386
++ + A + V A + + + + +LFL G +F+ + +++
Sbjct: 371 DIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFMQLVPPDLYYLATV 430
Query: 387 LVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTC 446
LV++ KF + SM+ ++ AE + R + +++ ++
Sbjct: 431 LVMVGKFGVTAAFSMVYVY-----------------TAELYPTVVRNMGVGVSSTAS-RL 472
Query: 447 NFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFFKVPETKGKSFEEIAAEFQKKSGSA 506
I++ F Y+ + + L + + + T F +PE+ G + + + G
Sbjct: 473 GSILSPYFVYLGAYDRFLPYILMGSLTILTAILTLF-LPESFGTPLPDTIDQMLRVKGMK 531
Query: 507 HR 508
HR
Sbjct: 532 HR 533
>gi|23510410 solute carrier family 22 member 1 isoform b [Homo
sapiens]
Length = 506
Score = 42.7 bits (99), Expect = 8e-04
Identities = 71/312 (22%), Positives = 125/312 (40%), Gaps = 41/312 (13%)
Query: 97 WSLSV--SSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILI 154
W L + S G + S G+ D GR +L +++ V +LM FS P+++ +
Sbjct: 146 WKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFS---PNYMSM 202
Query: 155 IAGRSISGLYC--GLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFIL 212
+ R + GL ++G I E + R + +Q+A G++ + GL + L
Sbjct: 203 LLFRLLQGLVSKGNWMAGYT--LITEFVGSGSRRTVAIMYQMAFTVGLV--ALTGLAYAL 258
Query: 213 GNYDLWHILLGLSGVRAILQSLLLFFC-PESPRYLY--------IKLDEEVKAKQ----- 258
++ + + L LL ++C PESPR+L IK+ + + K
Sbjct: 259 PHWRWLQLAVSL----PTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPP 314
Query: 259 -SLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQL---FTNSSYRQPILVALMLHVAQ 314
LK L +DVT+ ++ + +K + I + FT+S Q L+LH+
Sbjct: 315 ADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVLYQ----GLILHMGA 370
Query: 315 QFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMS 374
+ F YS + I A I + V ++ L+ A + I
Sbjct: 371 TSGNLYLDFLYSALV----EIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFISPD 426
Query: 375 GMFVCAIFMSVG 386
++ I M VG
Sbjct: 427 LHWLNIIIMCVG 438
>gi|24497480 solute carrier family 22 member 6 isoform d [Homo
sapiens]
Length = 519
Score = 42.7 bits (99), Expect = 8e-04
Identities = 67/305 (21%), Positives = 118/305 (38%), Gaps = 38/305 (12%)
Query: 96 LWSLSVSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILII 155
L L+ S + VG + + G+L D LGR K +++ + + V F+ P+ +
Sbjct: 133 LRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFA---PNFPIYC 189
Query: 156 AGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNY 215
A R +SG+ IS E P R +GT +IG + LG +
Sbjct: 190 AFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGT--------------LIGYVYSLGQF 235
Query: 216 DL---------WHILLGLSGVRAILQSLLLFFCPESPRYLYI--KLDEEVKAKQSLKRLR 264
L W L L + +F ES R+ +LD ++A Q + R+
Sbjct: 236 LLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARIN 295
Query: 265 GYDD----VTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGIN 320
G + ++ ++ ++E + + S ++L + R L ML A F+
Sbjct: 296 GKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFA--- 352
Query: 321 GIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCA 380
+Y Q G+S + I GAV++ V ++ GRR + + +C
Sbjct: 353 --YYGLVMDLQGFGVSIYLIQVI-FGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICI 409
Query: 381 IFMSV 385
+ V
Sbjct: 410 LLNGV 414
>gi|24497478 solute carrier family 22 member 6 isoform c [Homo
sapiens]
Length = 506
Score = 42.7 bits (99), Expect = 8e-04
Identities = 67/305 (21%), Positives = 118/305 (38%), Gaps = 38/305 (12%)
Query: 96 LWSLSVSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILII 155
L L+ S + VG + + G+L D LGR K +++ + + V F+ P+ +
Sbjct: 133 LRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFA---PNFPIYC 189
Query: 156 AGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNY 215
A R +SG+ IS E P R +GT +IG + LG +
Sbjct: 190 AFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGT--------------LIGYVYSLGQF 235
Query: 216 DL---------WHILLGLSGVRAILQSLLLFFCPESPRYLYI--KLDEEVKAKQSLKRLR 264
L W L L + +F ES R+ +LD ++A Q + R+
Sbjct: 236 LLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARIN 295
Query: 265 GYDD----VTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGIN 320
G + ++ ++ ++E + + S ++L + R L ML A F+
Sbjct: 296 GKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFA--- 352
Query: 321 GIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCA 380
+Y Q G+S + I GAV++ V ++ GRR + + +C
Sbjct: 353 --YYGLVMDLQGFGVSIYLIQVI-FGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICI 409
Query: 381 IFMSV 385
+ V
Sbjct: 410 LLNGV 414
>gi|24497476 solute carrier family 22 member 6 isoform b [Homo
sapiens]
Length = 550
Score = 42.7 bits (99), Expect = 8e-04
Identities = 67/305 (21%), Positives = 118/305 (38%), Gaps = 38/305 (12%)
Query: 96 LWSLSVSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILII 155
L L+ S + VG + + G+L D LGR K +++ + + V F+ P+ +
Sbjct: 133 LRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFA---PNFPIYC 189
Query: 156 AGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNY 215
A R +SG+ IS E P R +GT +IG + LG +
Sbjct: 190 AFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGT--------------LIGYVYSLGQF 235
Query: 216 DL---------WHILLGLSGVRAILQSLLLFFCPESPRYLYI--KLDEEVKAKQSLKRLR 264
L W L L + +F ES R+ +LD ++A Q + R+
Sbjct: 236 LLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARIN 295
Query: 265 GYDD----VTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGIN 320
G + ++ ++ ++E + + S ++L + R L ML A F+
Sbjct: 296 GKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFA--- 352
Query: 321 GIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCA 380
+Y Q G+S + I GAV++ V ++ GRR + + +C
Sbjct: 353 --YYGLVMDLQGFGVSIYLIQVI-FGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICI 409
Query: 381 IFMSV 385
+ V
Sbjct: 410 LLNGV 414
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.140 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,631,769
Number of Sequences: 37866
Number of extensions: 741309
Number of successful extensions: 2595
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 2505
Number of HSP's gapped (non-prelim): 82
length of query: 524
length of database: 18,247,518
effective HSP length: 107
effective length of query: 417
effective length of database: 14,195,856
effective search space: 5919671952
effective search space used: 5919671952
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.