Search of human proteins with 4557465

Search of human proteins with 4557465

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557465 cell death-inducing DFFA-like effector a isoform 1
[Homo sapiens]
         (219 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557465 cell death-inducing DFFA-like effector a isoform 1 [H...   439   e-124
gi|38158011 cell death-inducing DFFA-like effector a isoform 2 [...   417   e-117
gi|23943904 cell death-inducing DFFA-like effector c [Homo sapiens]   181   4e-46
gi|93102358 cell death-inducing DFFA-like effector b [Homo sapiens]   152   3e-37
gi|47132600 DNA fragmentation factor, 45kDa, alpha polypeptide i...    58   5e-09
gi|4758148 DNA fragmentation factor, 45kDa, alpha polypeptide is...    58   5e-09
gi|4758150 DNA fragmentation factor, 40 kD, beta polypeptide [Ho...    37   0.017
gi|62243586 ubiquitin-specific protease 21 [Homo sapiens]              30   1.2  
gi|74027267 ubiquitin-specific protease 21 [Homo sapiens]              30   1.2  
gi|190610047 late cornified envelope 6A [Homo sapiens]                 28   4.7  

>gi|4557465 cell death-inducing DFFA-like effector a isoform 1 [Homo
           sapiens]
          Length = 219

 Score =  439 bits (1129), Expect = e-124
 Identities = 219/219 (100%), Positives = 219/219 (100%)

Query: 1   MEAARDYAGALIRPLTFMGSQTKRVLFTPLMHPARPFRVSNHDRSSRRGVMASSLQELIS 60
           MEAARDYAGALIRPLTFMGSQTKRVLFTPLMHPARPFRVSNHDRSSRRGVMASSLQELIS
Sbjct: 1   MEAARDYAGALIRPLTFMGSQTKRVLFTPLMHPARPFRVSNHDRSSRRGVMASSLQELIS 60

Query: 61  KTLDALVIATGLVTLVLEEDGTVVDTEEFFQTLGDNTHFMILEKGQKWMPGSQHVPTCSP 120
           KTLDALVIATGLVTLVLEEDGTVVDTEEFFQTLGDNTHFMILEKGQKWMPGSQHVPTCSP
Sbjct: 61  KTLDALVIATGLVTLVLEEDGTVVDTEEFFQTLGDNTHFMILEKGQKWMPGSQHVPTCSP 120

Query: 121 PKRSGIARVTFDLYRLNPKDFIGCLNVKATMYEMYSVSYDIRCTGLKGLLRSLLRFLSYS 180
           PKRSGIARVTFDLYRLNPKDFIGCLNVKATMYEMYSVSYDIRCTGLKGLLRSLLRFLSYS
Sbjct: 121 PKRSGIARVTFDLYRLNPKDFIGCLNVKATMYEMYSVSYDIRCTGLKGLLRSLLRFLSYS 180

Query: 181 AQVTGQFLIYLGTYMLRVLDDKEERPSLRSQAKGRFTCG 219
           AQVTGQFLIYLGTYMLRVLDDKEERPSLRSQAKGRFTCG
Sbjct: 181 AQVTGQFLIYLGTYMLRVLDDKEERPSLRSQAKGRFTCG 219


>gi|38158011 cell death-inducing DFFA-like effector a isoform 2
           [Homo sapiens]
          Length = 253

 Score =  417 bits (1071), Expect = e-117
 Identities = 207/207 (100%), Positives = 207/207 (100%)

Query: 13  RPLTFMGSQTKRVLFTPLMHPARPFRVSNHDRSSRRGVMASSLQELISKTLDALVIATGL 72
           RPLTFMGSQTKRVLFTPLMHPARPFRVSNHDRSSRRGVMASSLQELISKTLDALVIATGL
Sbjct: 47  RPLTFMGSQTKRVLFTPLMHPARPFRVSNHDRSSRRGVMASSLQELISKTLDALVIATGL 106

Query: 73  VTLVLEEDGTVVDTEEFFQTLGDNTHFMILEKGQKWMPGSQHVPTCSPPKRSGIARVTFD 132
           VTLVLEEDGTVVDTEEFFQTLGDNTHFMILEKGQKWMPGSQHVPTCSPPKRSGIARVTFD
Sbjct: 107 VTLVLEEDGTVVDTEEFFQTLGDNTHFMILEKGQKWMPGSQHVPTCSPPKRSGIARVTFD 166

Query: 133 LYRLNPKDFIGCLNVKATMYEMYSVSYDIRCTGLKGLLRSLLRFLSYSAQVTGQFLIYLG 192
           LYRLNPKDFIGCLNVKATMYEMYSVSYDIRCTGLKGLLRSLLRFLSYSAQVTGQFLIYLG
Sbjct: 167 LYRLNPKDFIGCLNVKATMYEMYSVSYDIRCTGLKGLLRSLLRFLSYSAQVTGQFLIYLG 226

Query: 193 TYMLRVLDDKEERPSLRSQAKGRFTCG 219
           TYMLRVLDDKEERPSLRSQAKGRFTCG
Sbjct: 227 TYMLRVLDDKEERPSLRSQAKGRFTCG 253


>gi|23943904 cell death-inducing DFFA-like effector c [Homo sapiens]
          Length = 238

 Score =  181 bits (459), Expect = 4e-46
 Identities = 93/183 (50%), Positives = 125/183 (68%), Gaps = 6/183 (3%)

Query: 28  TPLMHPARPFRVSNHDRSSRRGVMASSLQELISKTLDALVIATGLVTLVLEEDGTVVDTE 87
           +P    ARP RVS  DRS R+G+MA SL++L+ K  D L++A     LVLEEDGT V+TE
Sbjct: 36  SPKAPRARPCRVSTADRSVRKGIMAYSLEDLLLKVRDTLMLADKPFFLVLEEDGTTVETE 95

Query: 88  EFFQTLGDNTHFMILEKGQKWMP----GSQHVPTCS--PPKRSGIARVTFDLYRLNPKDF 141
           E+FQ L  +T FM+L+KGQKW P    G++H  + S  P K+  +ARVTFDLY+LNP+DF
Sbjct: 96  EYFQALAGDTVFMVLQKGQKWQPPSEQGTRHPLSLSHKPAKKIDVARVTFDLYKLNPQDF 155

Query: 142 IGCLNVKATMYEMYSVSYDIRCTGLKGLLRSLLRFLSYSAQVTGQFLIYLGTYMLRVLDD 201
           IGCLNVKAT Y+ YS+SYD+ C G K +++   R+  +S Q TG  L+    Y+ ++LD 
Sbjct: 156 IGCLNVKATFYDTYSLSYDLHCCGAKRIMKEAFRWALFSMQATGHVLLGTSCYLQQLLDA 215

Query: 202 KEE 204
            EE
Sbjct: 216 TEE 218


>gi|93102358 cell death-inducing DFFA-like effector b [Homo sapiens]
          Length = 219

 Score =  152 bits (383), Expect = 3e-37
 Identities = 87/210 (41%), Positives = 128/210 (60%), Gaps = 11/210 (5%)

Query: 11  LIRPLTFMGSQTKRVLFTPLMHPARPFRVSNHDRSSRRGVMASSLQELISKTLDALVIAT 70
           L+R ++ + S+  R ++T    P RPFRV +H R+ R+G+ A++ QEL++K L+ L++  
Sbjct: 12  LLRSVSNISSEFGRRVWTSAPPPQRPFRVCDHKRTIRKGLTAATRQELLAKALETLLL-N 70

Query: 71  GLVTLVLEEDGTVVDTEEFFQTLGDNTHFMILEKGQKWMPGSQHVPTCS-----PPKRSG 125
           G++TLVLEEDGT VD+E+FFQ L D+T  M+L+ GQ W P    V +       P     
Sbjct: 71  GVLTLVLEEDGTAVDSEDFFQLLEDDTCLMVLQSGQSWSPTRSGVLSYGLGRERPKHSKD 130

Query: 126 IARVTFDLYRLNPKDFIGCLNVKATMYEMYSVSYDIRCTGLKGLLRSLLRFLSYSAQVTG 185
           IAR TFD+Y+ NP+D  G LNVKAT Y +YS+S D +  G K +LR LLR+ S   Q  G
Sbjct: 131 IARFTFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGLGPKKVLRELLRWTSTLLQGLG 190

Query: 186 QFLIYLGTYMLRVLDDKEERPSLRSQAKGR 215
             L+ + + +   ++  E+      Q KGR
Sbjct: 191 HMLLGISSTLRHAVEGAEQ-----WQQKGR 215


>gi|47132600 DNA fragmentation factor, 45kDa, alpha polypeptide
           isoform 2 [Homo sapiens]
          Length = 268

 Score = 58.2 bits (139), Expect = 5e-09
 Identities = 33/70 (47%), Positives = 43/70 (61%), Gaps = 3/70 (4%)

Query: 41  NHDRSSRRGVMASSLQELISKTLDALVIATGL--VTLVLEEDGTVVDTEEFFQTLGDNTH 98
           N+ R  + GV AS L++L SK  D L I   L  VTLVL EDGT+VD +++F  L  NT 
Sbjct: 26  NYSRE-QHGVAASCLEDLRSKACDILAIDKSLTPVTLVLAEDGTIVDDDDYFLCLPSNTK 84

Query: 99  FMILEKGQKW 108
           F+ L   +KW
Sbjct: 85  FVALASNEKW 94


>gi|4758148 DNA fragmentation factor, 45kDa, alpha polypeptide
           isoform 1 [Homo sapiens]
          Length = 331

 Score = 58.2 bits (139), Expect = 5e-09
 Identities = 33/70 (47%), Positives = 43/70 (61%), Gaps = 3/70 (4%)

Query: 41  NHDRSSRRGVMASSLQELISKTLDALVIATGL--VTLVLEEDGTVVDTEEFFQTLGDNTH 98
           N+ R  + GV AS L++L SK  D L I   L  VTLVL EDGT+VD +++F  L  NT 
Sbjct: 26  NYSRE-QHGVAASCLEDLRSKACDILAIDKSLTPVTLVLAEDGTIVDDDDYFLCLPSNTK 84

Query: 99  FMILEKGQKW 108
           F+ L   +KW
Sbjct: 85  FVALASNEKW 94


>gi|4758150 DNA fragmentation factor, 40 kD, beta polypeptide [Homo
           sapiens]
          Length = 338

 Score = 36.6 bits (83), Expect = 0.017
 Identities = 24/66 (36%), Positives = 35/66 (53%), Gaps = 2/66 (3%)

Query: 44  RSSRR-GVMASSLQELISKTLDALVIATGLVTLVLEEDGTVVDTEEFFQTLGDNTHFMIL 102
           RS R+ GV   S QE++ K      +      L L EDGT + TE++F ++ DN   ++L
Sbjct: 14  RSPRKFGVAGRSCQEVLRKGCLRFQLPERGSRLCLYEDGTEL-TEDYFPSVPDNAELVLL 72

Query: 103 EKGQKW 108
             GQ W
Sbjct: 73  TLGQAW 78


>gi|62243586 ubiquitin-specific protease 21 [Homo sapiens]
          Length = 565

 Score = 30.4 bits (67), Expect = 1.2
 Identities = 14/41 (34%), Positives = 22/41 (53%)

Query: 85  DTEEFFQTLGDNTHFMILEKGQKWMPGSQHVPTCSPPKRSG 125
           D +EF + L +  H  I  +G++  P   + P  SPP+R G
Sbjct: 301 DAQEFLKLLMERLHLEINRRGRRAPPILANGPVPSPPRRGG 341


>gi|74027267 ubiquitin-specific protease 21 [Homo sapiens]
          Length = 565

 Score = 30.4 bits (67), Expect = 1.2
 Identities = 14/41 (34%), Positives = 22/41 (53%)

Query: 85  DTEEFFQTLGDNTHFMILEKGQKWMPGSQHVPTCSPPKRSG 125
           D +EF + L +  H  I  +G++  P   + P  SPP+R G
Sbjct: 301 DAQEFLKLLMERLHLEINRRGRRAPPILANGPVPSPPRRGG 341


>gi|190610047 late cornified envelope 6A [Homo sapiens]
          Length = 80

 Score = 28.5 bits (62), Expect = 4.7
 Identities = 13/25 (52%), Positives = 16/25 (64%), Gaps = 2/25 (8%)

Query: 100 MILEKGQKWMPGSQHVPTCSPPKRS 124
           M  +K Q W P   +VP CSPP+RS
Sbjct: 1   MSQQKQQSWKP--PNVPKCSPPQRS 23


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,584,053
Number of Sequences: 37866
Number of extensions: 294489
Number of successful extensions: 627
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 616
Number of HSP's gapped (non-prelim): 10
length of query: 219
length of database: 18,247,518
effective HSP length: 98
effective length of query: 121
effective length of database: 14,536,650
effective search space: 1758934650
effective search space used: 1758934650
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.