Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 4507685
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507685 transient receptor potential cation channel,
subfamily C, member 1 [Homo sapiens]
(759 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507685 transient receptor potential cation channel, subfamil... 1526 0.0
gi|209863026 transient receptor potential cation channel, subfam... 636 0.0
gi|7706747 transient receptor potential cation channel, subfamil... 636 0.0
gi|209863024 transient receptor potential cation channel, subfam... 634 0.0
gi|6912736 transient receptor potential cation channel, subfamil... 625 e-179
gi|209863030 transient receptor potential cation channel, subfam... 614 e-176
gi|209863028 transient receptor potential cation channel, subfam... 531 e-151
gi|5730102 transient receptor potential cation channel, subfamil... 434 e-121
gi|194733735 transient receptor potential cation channel, subfam... 428 e-120
gi|4507687 transient receptor potential cation channel, subfamil... 428 e-120
gi|9966865 transient receptor potential cation channel, subfamil... 414 e-115
gi|209863032 transient receptor potential cation channel, subfam... 410 e-114
gi|169216484 PREDICTED: similar to transient receptor potential ... 155 1e-37
gi|4507689 transient receptor potential cation channel, subfamil... 84 6e-16
gi|239754785 PREDICTED: similar to transient receptor potential ... 64 7e-10
gi|239749299 PREDICTED: similar to transient receptor potential ... 64 7e-10
gi|239743393 PREDICTED: hypothetical protein XP_002342847, parti... 64 7e-10
gi|239509090 PREDICTED: similar to transient receptor potential ... 64 7e-10
gi|109689695 transient receptor potential cation channel, subfam... 63 9e-10
gi|94538366 transient receptor potential cation channel, subfami... 58 4e-08
gi|154091312 transient receptor potential cation channel, subfam... 47 9e-05
gi|154091308 transient receptor potential cation channel, subfam... 47 9e-05
gi|154091310 transient receptor potential cation channel, subfam... 47 9e-05
gi|154091320 transient receptor potential cation channel, subfam... 47 9e-05
gi|154091318 transient receptor potential cation channel, subfam... 47 9e-05
gi|154091316 transient receptor potential cation channel, subfam... 47 9e-05
gi|154091314 transient receptor potential cation channel, subfam... 47 9e-05
gi|74315354 transient receptor potential cation channel, subfami... 46 1e-04
gi|74315352 transient receptor potential cation channel, subfami... 46 1e-04
gi|74315350 transient receptor potential cation channel, subfami... 46 1e-04
>gi|4507685 transient receptor potential cation channel, subfamily
C, member 1 [Homo sapiens]
Length = 759
Score = 1526 bits (3952), Expect = 0.0
Identities = 759/759 (100%), Positives = 759/759 (100%)
Query: 1 MMAALYPSTDLSGASSSSLPSSPSSSSPNEVMALKDVREVKEENTLNEKLFLLACDKGDY 60
MMAALYPSTDLSGASSSSLPSSPSSSSPNEVMALKDVREVKEENTLNEKLFLLACDKGDY
Sbjct: 1 MMAALYPSTDLSGASSSSLPSSPSSSSPNEVMALKDVREVKEENTLNEKLFLLACDKGDY 60
Query: 61 YMVKKILEENSSGDLNINCVDVLGRNAVTITIENENLDILQLLLDYGCQKLMERIQNPEY 120
YMVKKILEENSSGDLNINCVDVLGRNAVTITIENENLDILQLLLDYGCQKLMERIQNPEY
Sbjct: 61 YMVKKILEENSSGDLNINCVDVLGRNAVTITIENENLDILQLLLDYGCQKLMERIQNPEY 120
Query: 121 STTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRL 180
STTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRL
Sbjct: 121 STTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRL 180
Query: 181 DIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLA 240
DIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLA
Sbjct: 181 DIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLA 240
Query: 241 QARNSRELEVILNHTSSDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTV 300
QARNSRELEVILNHTSSDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTV
Sbjct: 241 QARNSRELEVILNHTSSDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTV 300
Query: 301 WFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASY 360
WFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASY
Sbjct: 301 WFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASY 360
Query: 361 FTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEES 420
FTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEES
Sbjct: 361 FTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEES 420
Query: 421 RNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLF 480
RNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLF
Sbjct: 421 RNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLF 480
Query: 481 FMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGI 540
FMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGI
Sbjct: 481 FMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGI 540
Query: 541 FCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVV 600
FCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVV
Sbjct: 541 FCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVV 600
Query: 601 IVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYM 660
IVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYM
Sbjct: 601 IVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYM 660
Query: 661 ISSLSKWICSHTSKGKVKRQNSLKEWRNLKQKRDENYQKVMCCLVHRYLTSMRQKMQSTD 720
ISSLSKWICSHTSKGKVKRQNSLKEWRNLKQKRDENYQKVMCCLVHRYLTSMRQKMQSTD
Sbjct: 661 ISSLSKWICSHTSKGKVKRQNSLKEWRNLKQKRDENYQKVMCCLVHRYLTSMRQKMQSTD 720
Query: 721 QATVENLNELRQDLSKFRNEIRDLLGFRTSKYAMFYPRN 759
QATVENLNELRQDLSKFRNEIRDLLGFRTSKYAMFYPRN
Sbjct: 721 QATVENLNELRQDLSKFRNEIRDLLGFRTSKYAMFYPRN 759
>gi|209863026 transient receptor potential cation channel, subfamily
C, member 4 isoform beta [Homo sapiens]
Length = 893
Score = 636 bits (1640), Expect = 0.0
Identities = 354/763 (46%), Positives = 489/763 (64%), Gaps = 56/763 (7%)
Query: 37 VREVKEENTLN--EKLFLLACDKGDYYMVKKILEENSSG-DLNINCVDVLGRNAVTITIE 93
+R V+ E+ L+ EK +L A +KGDY VKK LEE +NINC+D LGR A+ I IE
Sbjct: 20 LRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIE 79
Query: 94 NENLDILQLLLDY-----------------GCQKLMERIQNP-------------EYST- 122
NENL++++LLL + G +L+ + P ++S
Sbjct: 80 NENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEF 139
Query: 123 TMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDI 182
T D+ P+ILAAH NNYEI+ +L+++ VS+P+PH V C C C + + DSLRHSR RL+I
Sbjct: 140 TPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNI 199
Query: 183 YRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQA 242
Y+ LASP+LI L+ EDP L AF+LS +L+ELS VE EF+++YEEL+RQCK FAKDLL Q
Sbjct: 200 YKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQT 259
Query: 243 RNSRELEVILNHTSSDEPLDKRGLLEERM--NLSRLKLAIKYNQKEFVSQSNCQQFLNTV 300
R+SRELE+ILN+ D L+EE+ +L+RLKLAIKY QKEFV+Q NCQQ L +
Sbjct: 260 RSSRELEIILNYR------DDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASR 313
Query: 301 WFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASY 360
W+ + G+RR+ K++T +G+ +PV S+CYLIAPKS G I PF+KFI H ASY
Sbjct: 314 WYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASY 373
Query: 361 FTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEES 420
TFL LL L S + N GP ++++++ W++G IW +IK++W GL+D++ +
Sbjct: 374 LTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDW 433
Query: 421 RNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLF 480
N + FVMNSLYLAT +LK+VA K+ R+ WD +HPTLVAE LFA AN+ S LRL
Sbjct: 434 WNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLI 493
Query: 481 FMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGI 540
++T +S LGPLQIS+G+ML D KFL ++ LVL +F GL QLY Y + C GI
Sbjct: 494 SLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY-YEETKGLTCKGI 552
Query: 541 FCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVV 600
CE+Q N+ F + T +LFW IF L + ++VT E FVGA + GTYNV+ +
Sbjct: 553 RCEKQ-NNAFSTLFETLQSLFWSIFGL--INLYVTNVKAQHEFTEFVGATMFGTYNVISL 609
Query: 601 IVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYM 660
+VL +L+AM++ S+QLIA+H D EWKFAR KLW+SYF++ TLP PFN+IPSPK++ Y+
Sbjct: 610 VVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYL 669
Query: 661 ISSLSKWICSHTSKGKVKRQ----NSLKEWRNLKQKRDENYQKVMCCLVHRYLTSMRQKM 716
I KWI +H K K++R+ ++ +R YQ+VM LV RY+ +M +
Sbjct: 670 I----KWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIRDA 725
Query: 717 QSTDQATVENLNELRQDLSKFRNEIRDLLGFRTSKYAMFYPRN 759
++ + T EN EL+QD+S FR E+ LL R SK + N
Sbjct: 726 KTEEGLTEENFKELKQDISSFRFEVLGLL--RGSKLSTIQSAN 766
>gi|7706747 transient receptor potential cation channel, subfamily
C, member 4 isoform alpha [Homo sapiens]
Length = 977
Score = 636 bits (1640), Expect = 0.0
Identities = 354/763 (46%), Positives = 489/763 (64%), Gaps = 56/763 (7%)
Query: 37 VREVKEENTLN--EKLFLLACDKGDYYMVKKILEENSSG-DLNINCVDVLGRNAVTITIE 93
+R V+ E+ L+ EK +L A +KGDY VKK LEE +NINC+D LGR A+ I IE
Sbjct: 20 LRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIE 79
Query: 94 NENLDILQLLLDY-----------------GCQKLMERIQNP-------------EYST- 122
NENL++++LLL + G +L+ + P ++S
Sbjct: 80 NENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEF 139
Query: 123 TMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDI 182
T D+ P+ILAAH NNYEI+ +L+++ VS+P+PH V C C C + + DSLRHSR RL+I
Sbjct: 140 TPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNI 199
Query: 183 YRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQA 242
Y+ LASP+LI L+ EDP L AF+LS +L+ELS VE EF+++YEEL+RQCK FAKDLL Q
Sbjct: 200 YKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQT 259
Query: 243 RNSRELEVILNHTSSDEPLDKRGLLEERM--NLSRLKLAIKYNQKEFVSQSNCQQFLNTV 300
R+SRELE+ILN+ D L+EE+ +L+RLKLAIKY QKEFV+Q NCQQ L +
Sbjct: 260 RSSRELEIILNYR------DDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASR 313
Query: 301 WFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASY 360
W+ + G+RR+ K++T +G+ +PV S+CYLIAPKS G I PF+KFI H ASY
Sbjct: 314 WYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASY 373
Query: 361 FTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEES 420
TFL LL L S + N GP ++++++ W++G IW +IK++W GL+D++ +
Sbjct: 374 LTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDW 433
Query: 421 RNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLF 480
N + FVMNSLYLAT +LK+VA K+ R+ WD +HPTLVAE LFA AN+ S LRL
Sbjct: 434 WNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLI 493
Query: 481 FMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGI 540
++T +S LGPLQIS+G+ML D KFL ++ LVL +F GL QLY Y + C GI
Sbjct: 494 SLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY-YEETKGLTCKGI 552
Query: 541 FCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVV 600
CE+Q N+ F + T +LFW IF L + ++VT E FVGA + GTYNV+ +
Sbjct: 553 RCEKQ-NNAFSTLFETLQSLFWSIFGL--INLYVTNVKAQHEFTEFVGATMFGTYNVISL 609
Query: 601 IVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYM 660
+VL +L+AM++ S+QLIA+H D EWKFAR KLW+SYF++ TLP PFN+IPSPK++ Y+
Sbjct: 610 VVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYL 669
Query: 661 ISSLSKWICSHTSKGKVKRQ----NSLKEWRNLKQKRDENYQKVMCCLVHRYLTSMRQKM 716
I KWI +H K K++R+ ++ +R YQ+VM LV RY+ +M +
Sbjct: 670 I----KWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIRDA 725
Query: 717 QSTDQATVENLNELRQDLSKFRNEIRDLLGFRTSKYAMFYPRN 759
++ + T EN EL+QD+S FR E+ LL R SK + N
Sbjct: 726 KTEEGLTEENFKELKQDISSFRFEVLGLL--RGSKLSTIQSAN 766
>gi|209863024 transient receptor potential cation channel, subfamily
C, member 4 isoform epsilon [Homo sapiens]
Length = 982
Score = 634 bits (1634), Expect = 0.0
Identities = 356/770 (46%), Positives = 490/770 (63%), Gaps = 65/770 (8%)
Query: 37 VREVKEENTLN--EKLFLLACDKGDYYMVKKILEENSSG-DLNINCVDVLGRNAVTITIE 93
+R V+ E+ L+ EK +L A +KGDY VKK LEE +NINC+D LGR A+ I IE
Sbjct: 20 LRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIE 79
Query: 94 NENLDILQLLLDY-----------------GCQKLMERIQNP-------------EYST- 122
NENL++++LLL + G +L+ + P ++S
Sbjct: 80 NENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEF 139
Query: 123 TMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDI 182
T D+ P+ILAAH NNYEI+ +L+++ VS+P+PH V C C C + + DSLRHSR RL+I
Sbjct: 140 TPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNI 199
Query: 183 YRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQA 242
Y+ LASP+LI L+ EDP L AF+LS +L+ELS VE EF+++YEEL+RQCK FAKDLL Q
Sbjct: 200 YKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQT 259
Query: 243 RNSRELEVILNHTSSDEPLDKRGLLEERM--NLSRLKLAIKYNQKEFVSQSNCQQFLNTV 300
R+SRELE+ILN+ D L+EE+ +L+RLKLAIKY QKEFV+Q NCQQ L +
Sbjct: 260 RSSRELEIILNYR------DDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASR 313
Query: 301 WFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASY 360
W+ + G+RR+ K++T +G+ +PV S+CYLIAPKS G I PF+KFI H ASY
Sbjct: 314 WYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASY 373
Query: 361 FTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEES 420
TFL LL L S + N GP ++++++ W++G IW +IK++W GL+D++ +
Sbjct: 374 LTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDW 433
Query: 421 RNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLF 480
N + FVMNSLYLAT +LK+VA K+ R+ WD +HPTLVAE LFA AN+ S LRL
Sbjct: 434 WNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLI 493
Query: 481 FMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGI 540
++T +S LGPLQIS+G+ML D KFL ++ LVL +F GL QLY Y + C GI
Sbjct: 494 SLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY-YEETKGLTCKGI 552
Query: 541 FCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVV 600
CE+Q N+ F + T +LFW IF L + ++VT E FVGA + GTYNV+ +
Sbjct: 553 RCEKQ-NNAFSTLFETLQSLFWSIFGL--INLYVTNVKAQHEFTEFVGATMFGTYNVISL 609
Query: 601 IVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYM 660
+VL +L+AM++ S+QLIA+H D EWKFAR KLW+SYF++ TLP PFN+IPSPK++ Y+
Sbjct: 610 VVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYL 669
Query: 661 ISSLSKWICSHTSKGKVKRQ-----------NSLKEWRNLKQKRDENYQKVMCCLVHRYL 709
I KWI +H K K++R+ + NL +R YQ+VM LV RY+
Sbjct: 670 I----KWIWTHLCKKKMRRKPESFGTIGVRTQHRRAADNL--RRHHQYQEVMRNLVKRYV 723
Query: 710 TSMRQKMQSTDQATVENLNELRQDLSKFRNEIRDLLGFRTSKYAMFYPRN 759
+M + ++ + T EN EL+QD+S FR E+ LL R SK + N
Sbjct: 724 AAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLL--RGSKLSTIQSAN 771
>gi|6912736 transient receptor potential cation channel, subfamily
C, member 5 [Homo sapiens]
Length = 973
Score = 625 bits (1611), Expect = e-179
Identities = 337/744 (45%), Positives = 486/744 (65%), Gaps = 45/744 (6%)
Query: 43 ENTLNEKLFLLACDKGDYYMVKKILEENSSG-DLNINCVDVLGRNAVTITIENENLDILQ 101
E + EK FL A +KGDY VK+ L+E ++NINC+D LGR+A+ I IENENL+I++
Sbjct: 28 ELSAEEKAFLNAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIME 87
Query: 102 LLLDY-----------------GCQKLMERIQNP-------------EYST-TMDVAPVI 130
LLL++ G +L+ + P ++S T D+ P++
Sbjct: 88 LLLNHSVYVGDALLYAIRKEVVGAVELLLSYRRPSGEKQVPTLMMDTQFSEFTPDITPIM 147
Query: 131 LAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDIYRCLASPA 190
LAAH NNYEI+ +L+++ V++P+PH + C C C + ++ DSLRHSR RL+IY+ LASP+
Sbjct: 148 LAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPS 207
Query: 191 LIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQARNSRELEV 250
LI L+ EDPIL AF L +LKELS VE EF+ +YEEL++QCK+FAKDLL QAR+SRELE+
Sbjct: 208 LIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELEI 267
Query: 251 ILNHTSS-DEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMSGYR 309
ILNH E LD ++ +L++LK+AIKY+QKEFV+Q NCQQ L T+W+ G+R
Sbjct: 268 ILNHRDDHSEELDP----QKYHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWR 323
Query: 310 RKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASYFTFLLLLNL 369
RK K++T +T+G +P+LS+ YLI+P+S G I PF+KFI H ASY TFL +L L
Sbjct: 324 RKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFMLLL 383
Query: 370 YSLVYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEESRNQLSFVMN 429
S + GP ++++++ W++G IW +IK +W G +++ + N + F MN
Sbjct: 384 ASQHIVRTDLHVQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFTEYIHDWWNLMDFAMN 443
Query: 430 SLYLATFALKVVAHNKFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSIL 489
SLYLAT +LK+VA+ K++ R++W+ +HPTL+AE LFA +N+LS LRL ++T +S L
Sbjct: 444 SLYLATISLKIVAYVKYNGSRPREEWEMWHPTLIAEALFAISNILSSLRLISLFTANSHL 503
Query: 490 GPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTS--KEQKDCVGIFCEQQSN 547
GPLQIS+G+ML D KFL ++ LVL +F GL QLY T E +C GI CE+Q N
Sbjct: 504 GPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETRAIDEPNNCKGIRCEKQ-N 562
Query: 548 DTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLL 607
+ F + T +LFW +F L + ++VT E FVGA + GTYNV+ ++VL +L
Sbjct: 563 NAFSTLFETLQSLFWSVFGLLN--LYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNML 620
Query: 608 VAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYMISSLSKW 667
+AM++ S+QLIA+H D EWKFAR KLW+SYFD+ TLPPPFNIIPSPK+ Y+ + +
Sbjct: 621 IAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFNNT 680
Query: 668 ICSHTSKGKVKRQNSLKEW--RNLKQK-RDENYQKVMCCLVHRYLTSMRQKMQSTDQATV 724
C +R+ +L+ + RN ++++YQ+V+ LV RY+ +M + ++ + T
Sbjct: 681 FCPKRDPDGRRRRRNLRSFTERNADSLIQNQHYQEVIRNLVKRYVAAMIRNSKTHEGLTE 740
Query: 725 ENLNELRQDLSKFRNEIRDLLGFR 748
EN EL+QD+S FR E+ DLLG R
Sbjct: 741 ENFKELKQDISSFRYEVLDLLGNR 764
>gi|209863030 transient receptor potential cation channel, subfamily
C, member 4 isoform delta [Homo sapiens]
Length = 836
Score = 614 bits (1584), Expect = e-176
Identities = 339/738 (45%), Positives = 474/738 (64%), Gaps = 54/738 (7%)
Query: 37 VREVKEENTLN--EKLFLLACDKGDYYMVKKILEENSSG-DLNINCVDVLGRNAVTITIE 93
+R V+ E+ L+ EK +L A +KGDY VKK LEE +NINC+D LGR A+ I IE
Sbjct: 20 LRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIE 79
Query: 94 NENLDILQLLLDY-----------------GCQKLMERIQNP-------------EYST- 122
NENL++++LLL + G +L+ + P ++S
Sbjct: 80 NENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEF 139
Query: 123 TMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDI 182
T D+ P+ILAAH NNYEI+ +L+++ VS+P+PH V C C C + + DSLRHSR RL+I
Sbjct: 140 TPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNI 199
Query: 183 YRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQA 242
Y+ LASP+LI L+ EDP L AF+LS +L+ELS VE EF+++YEEL+RQCK FAKDLL Q
Sbjct: 200 YKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQT 259
Query: 243 RNSRELEVILNHTSSDEPLDKRGLLEERM--NLSRLKLAIKYNQKEFVSQSNCQQFLNTV 300
R+SRELE+ILN+ D L+EE+ +L+RLKLAIKY QKEFV+Q NCQQ L +
Sbjct: 260 RSSRELEIILNYR------DDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASR 313
Query: 301 WFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASY 360
W+ + G+RR+ K++T +G+ +PV S+CYLIAPKS G I PF+KFI H ASY
Sbjct: 314 WYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASY 373
Query: 361 FTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEES 420
TFL LL L S + N GP ++++++ W++G IW +IK++W GL+D++ +
Sbjct: 374 LTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDW 433
Query: 421 RNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLF 480
N + FVMNSLYLAT +LK+VA K+ R+ WD +HPTLVAE LFA AN+ S LRL
Sbjct: 434 WNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLI 493
Query: 481 FMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGI 540
++T +S LGPLQIS+G+ML D KFL ++ LVL +F GL QLY Y + C GI
Sbjct: 494 SLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY-YEETKGLTCKGI 552
Query: 541 FCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVV 600
CE+Q N+ F + T +LFW IF L + ++VT E FVGA + GTYNV+ +
Sbjct: 553 RCEKQ-NNAFSTLFETLQSLFWSIFGL--INLYVTNVKAQHEFTEFVGATMFGTYNVISL 609
Query: 601 IVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYM 660
+VL +L+AM++ S+QLIA+H D EWKFAR KLW+SYF++ TLP PFN+IPSPK++ Y+
Sbjct: 610 VVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYL 669
Query: 661 ISSLSKWICSHTSKGKVKRQ----NSLKEWRNLKQKRDENYQKVMCCLVHRYLTSMRQKM 716
I KWI +H K K++R+ ++ +R YQ+VM LV RY+ +M +
Sbjct: 670 I----KWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIRDA 725
Query: 717 QSTDQATVENLNELRQDL 734
++ + A + L +++
Sbjct: 726 KTEEVARQQAAGPLERNI 743
>gi|209863028 transient receptor potential cation channel, subfamily
C, member 4 isoform gamma [Homo sapiens]
Length = 828
Score = 531 bits (1368), Expect = e-151
Identities = 293/619 (47%), Positives = 402/619 (64%), Gaps = 46/619 (7%)
Query: 37 VREVKEENTLN--EKLFLLACDKGDYYMVKKILEENSSG-DLNINCVDVLGRNAVTITIE 93
+R V+ E+ L+ EK +L A +KGDY VKK LEE +NINC+D LGR A+ I IE
Sbjct: 20 LRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIE 79
Query: 94 NENLDILQLLLDY-----------------GCQKLMERIQNP-------------EYST- 122
NENL++++LLL + G +L+ + P ++S
Sbjct: 80 NENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEF 139
Query: 123 TMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDI 182
T D+ P+ILAAH NNYEI+ +L+++ VS+P+PH V C C C + + DSLRHSR RL+I
Sbjct: 140 TPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNI 199
Query: 183 YRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQA 242
Y+ LASP+LI L+ EDP L AF+LS +L+ELS VE EF+++YEEL+RQCK FAKDLL Q
Sbjct: 200 YKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQT 259
Query: 243 RNSRELEVILNHTSSDEPLDKRGLLEERM--NLSRLKLAIKYNQKEFVSQSNCQQFLNTV 300
R+SRELE+ILN+ D L+EE+ +L+RLKLAIKY QKEFV+Q NCQQ L +
Sbjct: 260 RSSRELEIILNYR------DDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASR 313
Query: 301 WFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASY 360
W+ + G+RR+ K++T +G+ +PV S+CYLIAPKS G I PF+KFI H ASY
Sbjct: 314 WYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASY 373
Query: 361 FTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEES 420
TFL LL L S + N GP ++++++ W++G IW +IK++W GL+D++ +
Sbjct: 374 LTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDW 433
Query: 421 RNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLF 480
N + FVMNSLYLAT +LK+VA K+ R+ WD +HPTLVAE LFA AN+ S LRL
Sbjct: 434 WNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLI 493
Query: 481 FMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGI 540
++T +S LGPLQIS+G+ML D KFL ++ LVL +F GL QLY Y + C GI
Sbjct: 494 SLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY-YEETKGLTCKGI 552
Query: 541 FCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVV 600
CE+Q N+ F + T +LFW IF L + ++VT E FVGA + GTYNV+ +
Sbjct: 553 RCEKQ-NNAFSTLFETLQSLFWSIFGL--INLYVTNVKAQHEFTEFVGATMFGTYNVISL 609
Query: 601 IVLTKLLVAMLHKSFQLIA 619
+VL +L+AM++ S+QLIA
Sbjct: 610 VVLLNMLIAMMNNSYQLIA 628
Score = 46.2 bits (108), Expect = 1e-04
Identities = 27/68 (39%), Positives = 39/68 (57%), Gaps = 2/68 (2%)
Query: 692 KRDENYQKVMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEIRDLLGFRTSK 751
+R YQ+VM LV RY+ +M + ++ + T EN EL+QD+S FR E+ LL R SK
Sbjct: 636 RRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLL--RGSK 693
Query: 752 YAMFYPRN 759
+ N
Sbjct: 694 LSTIQSAN 701
>gi|5730102 transient receptor potential cation channel, subfamily
C, member 6 [Homo sapiens]
Length = 931
Score = 434 bits (1117), Expect = e-121
Identities = 279/825 (33%), Positives = 423/825 (51%), Gaps = 150/825 (18%)
Query: 45 TLNEKLFLLACDKGDYYMVKKILEENSSGDLNINCVDVLGRNAVTITIENENLDILQLLL 104
++ E+ FL A + G+ +V+K+LEE S LN+NCVD +G+NA+ + + NE+L+I +LLL
Sbjct: 96 SIEEERFLDAAEYGNIPVVRKMLEECHS--LNVNCVDYMGQNALQLAVANEHLEITELLL 153
Query: 105 ----------------DYGCQKLMERI-QNPEYST------------------------- 122
G +++E I +P ++
Sbjct: 154 KKENLSRVGDALLLAISKGYVRIVEAILSHPAFAEGKRLATSPSQSELQQDDFYAYDEDG 213
Query: 123 ---TMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFR 179
+ DV P+ILAAH YEI+ LL++ + +PH C+C C+ K K DS HSR R
Sbjct: 214 TRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCNDCNQKQKHDSFSHSRSR 273
Query: 180 LDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLL 239
++ Y+ LASPA + L+ EDP++ A ELS +L L+ +E EF+NDY++L+ QCK F LL
Sbjct: 274 INAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYKKLSMQCKDFVVGLL 333
Query: 240 AQARNSRELEVILNHTSSDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNT 299
RN+ E+E ILN G R NLSRLKLAIKY K+FV+ NCQQ L +
Sbjct: 334 DLCRNTEEVEAILNGDVETLQSGDHG----RPNLSRLKLAIKYEVKKFVAHPNCQQQLLS 389
Query: 300 VWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGAS 359
+W+ +SG R++ K + VL V I P L+L Y AP S+ G+I+ PFMKF+ H AS
Sbjct: 390 IWYENLSGLRQQTMAVKFLVVLAVAIGLPFLALIYWFAPCSKMGKIMRGPFMKFVAHAAS 449
Query: 360 YFTFLLLLNLYS--------LVYNEDKKNTMGPALER-------IDYLLILWIIGMIWSD 404
+ FL LL + + L+ NE + ++ L+I W+IGMIW++
Sbjct: 450 FTIFLGLLVMNAADRFEGTKLLPNETSTDNAKQLFRMKTSCFSWMEMLIISWVIGMIWAE 509
Query: 405 IKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAH---NKFHDFADRKD------- 454
K +W +G +++L E N L F M +++ A+F + +A +K D D
Sbjct: 510 CKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTK 569
Query: 455 ----------------WDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQ 498
WD P +++EGL+A A VLS+ R+ ++ + GPLQIS+G+
Sbjct: 570 VTLGDNVKYYNLARIKWDPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGR 629
Query: 499 MLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGIFCEQQSNDTFHSFIGTCF 558
++D KF+ +F++V +F IG+ LY +K+ N+ F + +
Sbjct: 630 TVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQ-------------NEAFTTVEESFK 676
Query: 559 ALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLI 618
LFW IF L+ V V +Y + +G V+ G YNV +VIVL +L+AM++ SFQ I
Sbjct: 677 TLFWAIFGLSEVKSVV--INYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEI 734
Query: 619 ANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYMISSLSKWIC--------- 669
+ D EWKFARAKLW SYF++ TLP PFN++PSPK++ Y++ L KWI
Sbjct: 735 EDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKSLFYLLLKLKKWISELFQGHKKG 794
Query: 670 --------------------SHTSKGKV---KRQNSLKEWRNLKQKRD----------EN 696
SH K+ K+Q + +++ D
Sbjct: 795 FQEDAEMNKINEEKKLGILGSHEDLSKLSLDKKQVGHNKQPSIRSSEDFHLNSFNNPPRQ 854
Query: 697 YQKVMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEI 741
YQK+M L+ RY+ + +S D+ L E++QD+S R E+
Sbjct: 855 YQKIMKRLIKRYVLQAQIDKES-DEVNEGELKEIKQDISSLRYEL 898
>gi|194733735 transient receptor potential cation channel, subfamily
C, member 3 isoform a [Homo sapiens]
Length = 921
Score = 428 bits (1101), Expect = e-120
Identities = 274/812 (33%), Positives = 420/812 (51%), Gaps = 145/812 (17%)
Query: 45 TLNEKLFLLACDKGDYYMVKKILEENSSGDLNINCVDVLGRNAVTITIENENLDILQLLL 104
T E+ FL A + G+ +V+K+LEE+ + LN+NCVD +G+NA+ + + NE+L++ +LLL
Sbjct: 110 TAEEERFLDAAEYGNIPVVRKMLEESKT--LNVNCVDYMGQNALQLAVGNEHLEVTELLL 167
Query: 105 ----------------DYGCQKLMERIQN-PEYSTTM----------------------- 124
G +++E I N P ++ +
Sbjct: 168 KKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDG 227
Query: 125 -----DVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFR 179
D+ P+ILAAH YE++ MLL + + +PH C+C C K + DS HSR R
Sbjct: 228 TRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSHSRSR 287
Query: 180 LDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLL 239
++ Y+ LASPA + L+ EDP+L A ELS +L +L+ +E EF+NDY +L+ QCK F +L
Sbjct: 288 INAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVL 347
Query: 240 AQARNSRELEVILN-HTSSDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLN 298
R+S E+E ILN S EPL+ + + +LSR+KLAIKY K+FV+ NCQQ L
Sbjct: 348 DLCRDSEEVEAILNGDLESAEPLE---VHRHKASLSRVKLAIKYEVKKFVAHPNCQQQLL 404
Query: 299 TVWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGA 358
T+W+ +SG R + K + VL V + P L++ Y IAP S+ G+I+ +PFMKF+ H A
Sbjct: 405 TIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHAA 464
Query: 359 SYFTFLLLLNLYSLVYNEDKK---NTMGPALERIDY-----------------LLILWII 398
S+ FL L LV+N + T P + DY L+++W++
Sbjct: 465 SFIIFLGL-----LVFNASDRFEGITTLPNITVTDYPKQIFRVKTTQFTWTEMLIMVWVL 519
Query: 399 GMIWSDIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAH---NKFHDFAD---- 451
GM+WS+ K LW EG +++ + N L F M S+++A F + +A K + D
Sbjct: 520 GMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQ 579
Query: 452 -------------------RKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPL 492
R W P +++EGL+A A VLS+ R+ ++ + GPL
Sbjct: 580 ESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPL 639
Query: 493 QISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGIFCEQQSNDTFHS 552
QIS+G+ ++D KF+ +F++V F+F IG+ LY + + N F +
Sbjct: 640 QISLGRTVKDIFKFMVLFIMVFFAFMIGMFILY-------------SYYLGAKVNAAFTT 686
Query: 553 FIGTCFALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLH 612
+ LFW IF L+ V V + Y + +G V+ G YNV +V+VL +L+AM++
Sbjct: 687 VEESFKTLFWSIFGLSEVTSVVLK--YDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMIN 744
Query: 613 KSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYMI----------- 661
S+Q I + D EWKFAR+KLWLSYFDD TLPPPF+++PSPK+ Y I
Sbjct: 745 SSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIVNFPKCRR 804
Query: 662 ------------SSLSKWICSHTSKGKVKRQNSLKEWRNLKQKRDENYQKVMCCLVHRYL 709
+S S+ S +V +S N + YQ++M L+ RY+
Sbjct: 805 RRLQKDIEMGMGNSKSRLNLFTQSNSRVFESHSFNSILN----QPTRYQQIMKRLIKRYV 860
Query: 710 TSMRQKMQSTDQATVENLNELRQDLSKFRNEI 741
Q + D+ L E++QD+S R E+
Sbjct: 861 LK-AQVDKENDEVNEGELKEIKQDISSLRYEL 891
>gi|4507687 transient receptor potential cation channel, subfamily
C, member 3 isoform b [Homo sapiens]
Length = 848
Score = 428 bits (1101), Expect = e-120
Identities = 274/812 (33%), Positives = 420/812 (51%), Gaps = 145/812 (17%)
Query: 45 TLNEKLFLLACDKGDYYMVKKILEENSSGDLNINCVDVLGRNAVTITIENENLDILQLLL 104
T E+ FL A + G+ +V+K+LEE+ + LN+NCVD +G+NA+ + + NE+L++ +LLL
Sbjct: 37 TAEEERFLDAAEYGNIPVVRKMLEESKT--LNVNCVDYMGQNALQLAVGNEHLEVTELLL 94
Query: 105 ----------------DYGCQKLMERIQN-PEYSTTM----------------------- 124
G +++E I N P ++ +
Sbjct: 95 KKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDG 154
Query: 125 -----DVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFR 179
D+ P+ILAAH YE++ MLL + + +PH C+C C K + DS HSR R
Sbjct: 155 TRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSHSRSR 214
Query: 180 LDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLL 239
++ Y+ LASPA + L+ EDP+L A ELS +L +L+ +E EF+NDY +L+ QCK F +L
Sbjct: 215 INAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVL 274
Query: 240 AQARNSRELEVILN-HTSSDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLN 298
R+S E+E ILN S EPL+ + + +LSR+KLAIKY K+FV+ NCQQ L
Sbjct: 275 DLCRDSEEVEAILNGDLESAEPLE---VHRHKASLSRVKLAIKYEVKKFVAHPNCQQQLL 331
Query: 299 TVWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGA 358
T+W+ +SG R + K + VL V + P L++ Y IAP S+ G+I+ +PFMKF+ H A
Sbjct: 332 TIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHAA 391
Query: 359 SYFTFLLLLNLYSLVYNEDKK---NTMGPALERIDY-----------------LLILWII 398
S+ FL L LV+N + T P + DY L+++W++
Sbjct: 392 SFIIFLGL-----LVFNASDRFEGITTLPNITVTDYPKQIFRVKTTQFTWTEMLIMVWVL 446
Query: 399 GMIWSDIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAH---NKFHDFAD---- 451
GM+WS+ K LW EG +++ + N L F M S+++A F + +A K + D
Sbjct: 447 GMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQ 506
Query: 452 -------------------RKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPL 492
R W P +++EGL+A A VLS+ R+ ++ + GPL
Sbjct: 507 ESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPL 566
Query: 493 QISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGIFCEQQSNDTFHS 552
QIS+G+ ++D KF+ +F++V F+F IG+ LY + + N F +
Sbjct: 567 QISLGRTVKDIFKFMVLFIMVFFAFMIGMFILY-------------SYYLGAKVNAAFTT 613
Query: 553 FIGTCFALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLH 612
+ LFW IF L+ V V + Y + +G V+ G YNV +V+VL +L+AM++
Sbjct: 614 VEESFKTLFWSIFGLSEVTSVVLK--YDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMIN 671
Query: 613 KSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYMI----------- 661
S+Q I + D EWKFAR+KLWLSYFDD TLPPPF+++PSPK+ Y I
Sbjct: 672 SSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIVNFPKCRR 731
Query: 662 ------------SSLSKWICSHTSKGKVKRQNSLKEWRNLKQKRDENYQKVMCCLVHRYL 709
+S S+ S +V +S N + YQ++M L+ RY+
Sbjct: 732 RRLQKDIEMGMGNSKSRLNLFTQSNSRVFESHSFNSILN----QPTRYQQIMKRLIKRYV 787
Query: 710 TSMRQKMQSTDQATVENLNELRQDLSKFRNEI 741
Q + D+ L E++QD+S R E+
Sbjct: 788 LK-AQVDKENDEVNEGELKEIKQDISSLRYEL 818
>gi|9966865 transient receptor potential cation channel, subfamily
C, member 7 [Homo sapiens]
Length = 862
Score = 414 bits (1063), Expect = e-115
Identities = 265/806 (32%), Positives = 413/806 (51%), Gaps = 132/806 (16%)
Query: 45 TLNEKLFLLACDKGDYYMVKKILEENSSGDLNINCVDVLGRNAVTITIENENLDILQLLL 104
T E+ FL + + G+ +V+K+LEE+ + LN NCVD +G+NA+ + + NE+L++ +LLL
Sbjct: 41 TPEEERFLDSAEYGNIPVVRKMLEESKT--LNFNCVDYMGQNALQLAVGNEHLEVTELLL 98
Query: 105 ----------------DYGCQKLMERIQN-PEYST------------------------- 122
G +++E I N P ++
Sbjct: 99 KKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDEDG 158
Query: 123 ---TMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFR 179
+ D+ P+ILAAH YEI+ +LL + + +PH C+C C+ K +KDS HSR R
Sbjct: 159 TRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSRSR 218
Query: 180 LDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLL 239
++ Y+ LAS A + L+ EDP+L A ELS +L L+ +E EF+NDY +L+ QCK F +L
Sbjct: 219 MNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVGVL 278
Query: 240 AQARNSRELEVILNHTSSDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNT 299
R++ E+E ILN + + R +LSR+KLAIKY K+FV+ NCQQ L T
Sbjct: 279 DLCRDTEEVEAILNGDVNFQVWSD----HHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLT 334
Query: 300 VWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGAS 359
+W+ +SG R++ K + V V I P L++ Y IAP S+ GR + +PFMKF+ H S
Sbjct: 335 MWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKLGRTLRSPFMKFVAHAVS 394
Query: 360 YFTFLLLL------------NLYSLVYNEDKKNTMGPALERIDY---LLILWIIGMIWSD 404
+ FL LL L + + + K + + L++ W++GMIWS+
Sbjct: 395 FTIFLGLLVVNASDRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIWSE 454
Query: 405 IKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVA--------------------HN 444
K +W EG +++ N L F M S+++A+F + +A HN
Sbjct: 455 CKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKATEAQLYVDQHVQDDTLHN 514
Query: 445 -------KFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQISMG 497
+ +A K W + P +++EGL+A A VLS+ R+ ++ + GPLQIS+G
Sbjct: 515 VSLPPEVAYFTYARDKWWPS-DPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLG 573
Query: 498 QMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGIFCEQQSNDTFHSFIGTC 557
+ ++D KF+ +F++V +F IG+ LY + + N F + +
Sbjct: 574 RTVKDIFKFMVIFIMVFVAFMIGMFNLY-------------SYYRGAKYNPAFTTVEESF 620
Query: 558 FALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQL 617
LFW IF L+ V V + Y + +G V+ G YNV +V+VL +L+AM++ S+Q
Sbjct: 621 KTLFWSIFGLSEVISVVLK--YDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQE 678
Query: 618 IANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYMISSLSKW---ICSHTSK 674
I D EWKFARAKLWLSYFD+ TLP PFN++PSPK+ Y+I + +C +K
Sbjct: 679 IEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKSKAK 738
Query: 675 G---------------KVKRQNSLKEWRNLKQ----KRDENYQKVMCCLVHRYLTSMRQK 715
K + Q ++ NL + YQK+M L+ RY+ Q
Sbjct: 739 SCENDLEMGMLNSKFKKTRYQAGMRNSENLTANNTLSKPTRYQKIMKRLIKRYVLK-AQV 797
Query: 716 MQSTDQATVENLNELRQDLSKFRNEI 741
+ D+ L E++QD+S R E+
Sbjct: 798 DRENDEVNEGELKEIKQDISSLRYEL 823
>gi|209863032 transient receptor potential cation channel, subfamily
C, member 4 isoform zeta [Homo sapiens]
Length = 804
Score = 410 bits (1053), Expect = e-114
Identities = 217/480 (45%), Positives = 306/480 (63%), Gaps = 14/480 (2%)
Query: 284 QKEFVSQSNCQQFLNTVWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFG 343
+K+FV+Q NCQQ L + W+ + G+RR+ K++T +G+ +PV S+CYLIAPKS G
Sbjct: 124 EKQFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG 183
Query: 344 RIIHTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGMIWS 403
I PF+KFI H ASY TFL LL L S + N GP ++++++ W++G IW
Sbjct: 184 LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWG 243
Query: 404 DIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLV 463
+IK++W GL+D++ + N + FVMNSLYLAT +LK+VA K+ R+ WD +HPTLV
Sbjct: 244 EIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLV 303
Query: 464 AEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQ 523
AE LFA AN+ S LRL ++T +S LGPLQIS+G+ML D KFL ++ LVL +F GL Q
Sbjct: 304 AEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQ 363
Query: 524 LYDKGYTSKEQKDCVGIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGEEL 583
LY Y + C GI CE+Q N+ F + T +LFW IF L + ++VT E
Sbjct: 364 LYFY-YEETKGLTCKGIRCEKQ-NNAFSTLFETLQSLFWSIFGL--INLYVTNVKAQHEF 419
Query: 584 QSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCT 643
FVGA + GTYNV+ ++VL +L+AM++ S+QLIA+H D EWKFAR KLW+SYF++ T
Sbjct: 420 TEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGT 479
Query: 644 LPPPFNIIPSPKTICYMISSLSKWICSHTSKGKVKRQ----NSLKEWRNLKQKRDENYQK 699
LP PFN+IPSPK++ Y+I KWI +H K K++R+ ++ +R YQ+
Sbjct: 480 LPTPFNVIPSPKSLWYLI----KWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQE 535
Query: 700 VMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEIRDLLGFRTSKYAMFYPRN 759
VM LV RY+ +M + ++ + T EN EL+QD+S FR E+ LL R SK + N
Sbjct: 536 VMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLL--RGSKLSTIQSAN 593
Score = 66.2 bits (160), Expect = 1e-10
Identities = 37/73 (50%), Positives = 51/73 (69%), Gaps = 3/73 (4%)
Query: 37 VREVKEENTLN--EKLFLLACDKGDYYMVKKILEENSSG-DLNINCVDVLGRNAVTITIE 93
+R V+ E+ L+ EK +L A +KGDY VKK LEE +NINC+D LGR A+ I IE
Sbjct: 20 LRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIE 79
Query: 94 NENLDILQLLLDY 106
NENL++++LLL +
Sbjct: 80 NENLELIELLLSF 92
>gi|169216484 PREDICTED: similar to transient receptor potential
channel subfamily C member 6 [Homo sapiens]
Length = 304
Score = 155 bits (393), Expect = 1e-37
Identities = 94/297 (31%), Positives = 152/297 (51%), Gaps = 43/297 (14%)
Query: 399 GMIWSDIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVA---------------- 442
GMIW++ K +W +G +++L E N L F M ++ A+F + A
Sbjct: 17 GMIWAECKEIWTQGPKEYLFELWNMLDFGMLAILSASFIARFRAFWHASKAQSITDASDT 76
Query: 443 -----------HNKFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGP 491
+ K++ A R++WD P +V+EGL A A VLS+ + + + GP
Sbjct: 77 LKDLTKVTLGDNVKYYSLA-RREWDPSDPRMVSEGLCAVAVVLSFSGIACILPANESFGP 135
Query: 492 LQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGIFCEQQSNDTFH 551
LQ+S+G ++D +F+ +F++V +F IG+ LY + + + N+ F
Sbjct: 136 LQMSLGGAVKDIFRFMLIFIMVFVAFMIGMFNLY-------------SYYIDVKQNEAFT 182
Query: 552 SFIGTCFALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAML 611
+ + LFW F L+ V V +Y + +G V+ G Y+V +VIVL +L+AM+
Sbjct: 183 TVEESFKTLFWATFVLSAVKSVV--INYSHKFIENIGYVLYGVYDVTMVIVLLNMLIAMI 240
Query: 612 HKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYMISSLSKWI 668
+ S Q I + D EWKFARAKLW S F + LP PFN++P P ++ ++ L WI
Sbjct: 241 NSSLQEIEDDADVEWKFARAKLWFSCFGEGRALPVPFNLVPGPGSLFCLLLKLKGWI 297
>gi|4507689 transient receptor potential cation channel, subfamily M,
member 2 [Homo sapiens]
Length = 1503
Score = 83.6 bits (205), Expect = 6e-16
Identities = 125/561 (22%), Positives = 224/561 (39%), Gaps = 71/561 (12%)
Query: 191 LIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQARNSRELEV 250
+I +D I A S LKELS E + + E LA LA+ R + V
Sbjct: 640 IIWAQSQDCIAAALACSKILKELSKEEEDTDSSEEMLA----------LAEEYEHRAIGV 689
Query: 251 ILNHTSSDEPLDKRGLL---EERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMS- 306
DE ++ L E + L+LA++ +FVS Q FL VW+GQ+S
Sbjct: 690 FTECYRKDEERAQKLLTRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLSV 749
Query: 307 --GYRRKPTCKKIMTVLTVG-IFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASYFTF 363
G R C +L G I + L + P ++ P + F ++ SYF F
Sbjct: 750 DNGLWRVTLCMLAFPLLLTGLISFREKRLQDVGTPAARARAFFTAPVVVFHLNILSYFAF 809
Query: 364 LLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLE-DFLEESRN 422
L L +V P + + LW+ ++ ++++L+Y+ E ++++
Sbjct: 810 LCLFAYVLMV-------DFQPVPSWCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAAL 862
Query: 423 QLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFM 482
S N L + L V R +P V + + +L LRL +
Sbjct: 863 YFSDFWNKLDVGAILLFVAG------LTCRLIPATLYPGRV---ILSLDFILFCLRLMHI 913
Query: 483 YTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGIFC 542
+T S LGP I + +M++D F +FLL ++ + G+ + + ++ +F
Sbjct: 914 FTISKTLGPKIIIVKRMMKDV--FFFLFLLAVWVVSFGVAK---QAILIHNERRVDWLF- 967
Query: 543 EQQSNDTFHSFIGTCFALFWYI----FSLAHVA-----IFVTRFSYGEELQ------SFV 587
+HS++ + YI F+ H + + + + Q ++
Sbjct: 968 ---RGAVYHSYLTIFGQIPGYIDGVNFNPEHCSPNGTDPYKPKCPESDATQQRPAFPEWL 1024
Query: 588 GAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPP 647
+++ Y + I+L LL+AM + +FQ + H D+ WKF R L + + + PPP
Sbjct: 1025 TVLLLCLYLLFTNILLLNLLIAMFNYTFQQVQEHTDQIWKFQRHDL-IEEYHGRPAAPPP 1083
Query: 648 FNIIPSPKTICYMISSLSKWICSHTSKGKVKRQNSLKEWRNLKQKRDENYQKVMCCLVHR 707
F ++S L +I K KR LK L++ + L
Sbjct: 1084 F----------ILLSHLQLFIKRVVLKTPAKRHKQLK--NKLEKNEEAALLSWEIYLKEN 1131
Query: 708 YLTSMRQKMQSTDQATVENLN 728
YL + + + + + +E+++
Sbjct: 1132 YLQNRQFQQKQRPEQKIEDIS 1152
>gi|239754785 PREDICTED: similar to transient receptor potential
cation channel, subfamily C, member 6, partial [Homo
sapiens]
Length = 182
Score = 63.5 bits (153), Expect = 7e-10
Identities = 43/160 (26%), Positives = 80/160 (50%), Gaps = 28/160 (17%)
Query: 403 SDIKRLWYEGLEDFLEESRNQLSF----VMNSLYLATF--------ALKVVAHN------ 444
++ K +W +G +++L E N L F + +L++A F A ++ N
Sbjct: 3 TECKEIWTQGPKEYLFELWNMLDFGMLVIFTALFIARFRAFWHASKAQSIIDANDTLKDL 62
Query: 445 ---------KFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQIS 495
K+++ A R++W P +V+EGL A A VLS+ + + + GPLQ S
Sbjct: 63 TEVTLGDNVKYYNLA-RREWVPSDPWVVSEGLCAVAVVLSFSGIACILPANESFGPLQTS 121
Query: 496 MGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQK 535
+G ++D +F+ +F++V +F IG+ LY +K+ +
Sbjct: 122 LGGAVKDIFRFMVIFIMVFVAFMIGMFNLYSYYIGAKQNE 161
>gi|239749299 PREDICTED: similar to transient receptor potential
cation channel, subfamily C, member 6, partial [Homo
sapiens]
Length = 182
Score = 63.5 bits (153), Expect = 7e-10
Identities = 43/160 (26%), Positives = 80/160 (50%), Gaps = 28/160 (17%)
Query: 403 SDIKRLWYEGLEDFLEESRNQLSF----VMNSLYLATF--------ALKVVAHN------ 444
++ K +W +G +++L E N L F + +L++A F A ++ N
Sbjct: 3 TECKEIWTQGPKEYLFELWNMLDFGMLVIFTALFIARFRAFWHASKAQSIIDANDTLKDL 62
Query: 445 ---------KFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQIS 495
K+++ A R++W P +V+EGL A A VLS+ + + + GPLQ S
Sbjct: 63 TEVTLGDNVKYYNLA-RREWVPSDPWVVSEGLCAVAVVLSFSGIACILPANESFGPLQTS 121
Query: 496 MGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQK 535
+G ++D +F+ +F++V +F IG+ LY +K+ +
Sbjct: 122 LGGAVKDIFRFMVIFIMVFVAFMIGMFNLYSYYIGAKQNE 161
>gi|239743393 PREDICTED: hypothetical protein XP_002342847, partial
[Homo sapiens]
Length = 182
Score = 63.5 bits (153), Expect = 7e-10
Identities = 43/160 (26%), Positives = 80/160 (50%), Gaps = 28/160 (17%)
Query: 403 SDIKRLWYEGLEDFLEESRNQLSF----VMNSLYLATF--------ALKVVAHN------ 444
++ K +W +G +++L E N L F + +L++A F A ++ N
Sbjct: 3 TECKEIWTQGPKEYLFELWNMLDFGMLVIFTALFIARFRAFWHASKAQSIIDANDTLKDL 62
Query: 445 ---------KFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQIS 495
K+++ A R++W P +V+EGL A A VLS+ + + + GPLQ S
Sbjct: 63 TEVTLGDNVKYYNLA-RREWVPSDPWVVSEGLCAVAVVLSFSGIACILPANESFGPLQTS 121
Query: 496 MGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQK 535
+G ++D +F+ +F++V +F IG+ LY +K+ +
Sbjct: 122 LGGAVKDIFRFMVIFIMVFVAFMIGMFNLYSYYIGAKQNE 161
>gi|239509090 PREDICTED: similar to transient receptor potential
cation channel, subfamily C, member 6, partial [Homo
sapiens]
Length = 182
Score = 63.5 bits (153), Expect = 7e-10
Identities = 43/160 (26%), Positives = 80/160 (50%), Gaps = 28/160 (17%)
Query: 403 SDIKRLWYEGLEDFLEESRNQLSF----VMNSLYLATF--------ALKVVAHN------ 444
++ K +W +G +++L E N L F + +L++A F A ++ N
Sbjct: 3 TECKEIWTQGPKEYLFELWNMLDFGMLVIFTALFIARFRAFWHASKAQSIIDANDTLKDL 62
Query: 445 ---------KFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQIS 495
K+++ A R++W P +V+EGL A A VLS+ + + + GPLQ S
Sbjct: 63 TEVTLGDNVKYYNLA-RREWVPSDPWVVSEGLCAVAVVLSFSGIACILPANESFGPLQTS 121
Query: 496 MGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQK 535
+G ++D +F+ +F++V +F IG+ LY +K+ +
Sbjct: 122 LGGAVKDIFRFMVIFIMVFVAFMIGMFNLYSYYIGAKQNE 161
>gi|109689695 transient receptor potential cation channel, subfamily
M, member 8 [Homo sapiens]
Length = 1104
Score = 63.2 bits (152), Expect = 9e-10
Identities = 110/542 (20%), Positives = 210/542 (38%), Gaps = 92/542 (16%)
Query: 239 LAQARNSRELEVILNHTSSDEPLDKRGLL---EERMNLSRLKLAIKYNQKEFVSQSNCQQ 295
LA +R +E+ SSDE L ++ L+ E + L+LA++ + F++Q Q
Sbjct: 617 LANEYETRAVELFTECYSSDEDLAEQLLVYSCEAWGGSNCLELAVEATDQHFIAQPGVQN 676
Query: 296 FLNTVWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGR----------I 345
FL+ W+G++S R K I+ + + P++ ++ K +
Sbjct: 677 FLSKQWYGEIS--RDTKNWKIILCLFII----PLVGCGFVSFRKKPVDKHKKLLWYYVAF 730
Query: 346 IHTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGMIWSDI 405
+PF+ F + Y FLL L++ V D + P L++ ++ +++ D
Sbjct: 731 FTSPFVVFSWNVVFYIAFLL---LFAYVLLMDFHSVPHP-----PELVLYSLVFVLFCDE 782
Query: 406 KRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLVAE 465
R WY ++ + N + + ++A ++ + NK ++ R
Sbjct: 783 VRQWYVNGVNYFTDLWNVMDTLGLFYFIAGIVFRLHSSNKSSLYSGRV------------ 830
Query: 466 GLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLY 525
+F ++ LRL ++T S LGP I + +ML D FL +F + + +F + +
Sbjct: 831 -IFCLDYIIFTLRLIHIFTVSRNLGPKIIMLQRMLIDVFFFLFLFAVWMVAFGVARQGIL 889
Query: 526 DKGYTSKEQKDCVGIFCEQQSNDTFHSFIGTCF-ALFWYI--------FSLAHVA----- 571
+ EQ+ F S I + A+F + + AH
Sbjct: 890 RQN--------------EQRWRWIFRSVIYEPYLAMFGQVPSDVDGTTYDFAHCTFTGNE 935
Query: 572 ---IFVTRFSYG-EELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWK 627
+ V + ++ +V Y + I+L LLVAM + + + D+ WK
Sbjct: 936 SKPLCVELDEHNLPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGTVQENNDQVWK 995
Query: 628 FARAKLWLSYFDDKCTLPPPF-------NIIPSPKTICYMISSLSKWICSHTSKGKVKRQ 680
F R L Y + +P PF ++ C ++ +C ++
Sbjct: 996 FQRYFLVQEYC-SRLNIPFPFIVFAYFYMVVKKCFKCCCKEKNMESSVCCFKNE-----D 1049
Query: 681 NSLKEWRNLKQKRDENYQKVMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNE 740
N W + + ENY + + MR + + D LN+L+ L + N+
Sbjct: 1050 NETLAWEGVMK---ENYLVKINTKANDTSEEMRHRFRQLD----TKLNDLKGLLKEIANK 1102
Query: 741 IR 742
I+
Sbjct: 1103 IK 1104
>gi|94538366 transient receptor potential cation channel, subfamily M,
member 1 [Homo sapiens]
Length = 1603
Score = 57.8 bits (138), Expect = 4e-08
Identities = 101/567 (17%), Positives = 218/567 (38%), Gaps = 117/567 (20%)
Query: 248 LEVILNHTSSDEPLDKRGLLEERMNLSR---LKLAIKYNQKEFVSQSNCQQFLNTVWFGQ 304
LE++ DE + + L E N S LKLA+ ++F++ + Q L +W G+
Sbjct: 681 LELLDQSYKHDEQIAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGR 740
Query: 305 MSGYRRKPTCKKIMTVLTVGI-----FWPVLSLCYLIAPKSQFGR--------------- 344
+ R+ P K IM +L F Y + +++ G+
Sbjct: 741 LR-MRKNPGLKVIMGILLPPTILFLEFRTYDDFSYQTSKENEDGKEKEEENTDANADAGS 799
Query: 345 -----------------------IIHTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKNT 381
+ P +KF + SY +LLL N LV +
Sbjct: 800 RKGDEENEHKKQRSIPIGTKICEFYNAPIVKFWFYTISYLGYLLLFNYVILVRMDG---- 855
Query: 382 MGPALERIDYLLILWIIGMIWSDIKRLWY-------EGLEDFLEESRNQLSFVMNSLYLA 434
P+L+ ++++I +I+ + I+ + + ++ +L+E N + + + ++
Sbjct: 856 -WPSLQ--EWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWN----ITDLVAIS 908
Query: 435 TFALKVVAHNKFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQI 494
TF + + + + ++ + Y+R+ ++ + LGP +
Sbjct: 909 TFMIGAILRLQNQPYMG-----------YGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVM 957
Query: 495 SMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGIFCEQQSNDTFHSFI 554
+G+M+ D F+ + L+VL SF + + + ++
Sbjct: 958 MIGKMMIDMLYFVVIMLVVLMSFGVARQAIL-----------------HPEEKPSWKLAR 1000
Query: 555 GTCFALFWYIFSLA---HVAIFVTRFS-------YGEELQ--------SFVGAVIVGTYN 596
+ +W I+ + ++ + Y EE + +++ ++ Y
Sbjct: 1001 NIFYMPYWMIYGEVFADQIDLYAMEINPPCGENLYDEEGKRLPPCIPGAWLTPALMACYL 1060
Query: 597 VVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKT 656
+V I+L LL+A+ + +F + + ++ WKF R +L ++ F D+ LPPP I+
Sbjct: 1061 LVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMT-FHDRPVLPPPMIIL---SH 1116
Query: 657 ICYMISSLSKWICSHTSKGKVKRQNSLKEWRNLKQKRDENYQKVMCCLVHRYLTSMRQKM 716
I +I LS + +R LK + + ++ + + + C V + +
Sbjct: 1117 IYIIIMRLSGRCRKKREGDQEERDRGLKLFLSDEELKRLHEFEEQC--VQEHFREKEDEQ 1174
Query: 717 QSTDQATVENLNELRQDLSKFRNEIRD 743
QS+ + +E +++S EI +
Sbjct: 1175 QSSSDERIRVTSERVENMSMRLEEINE 1201
>gi|154091312 transient receptor potential cation channel, subfamily
M, member 3 isoform b [Homo sapiens]
Length = 1566
Score = 46.6 bits (109), Expect = 9e-05
Identities = 68/322 (21%), Positives = 131/322 (40%), Gaps = 56/322 (17%)
Query: 347 HTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGM---IWS 403
+ P +KF + +Y +L+L N LV E +T + I Y+ L I M + S
Sbjct: 726 NAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIV--ISYIFTLGIEKMREILMS 783
Query: 404 DIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLV 463
+ +L + ++ +L+E N + L+ L++ D R D
Sbjct: 784 EPGKL-LQKVKVWLQEYWNVTDLIAILLFSVGMILRL------QDQPFRSD--------- 827
Query: 464 AEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQ 523
++ + Y+RL ++ + LGP + +G+M+ D F+ + L+VL SF +
Sbjct: 828 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 887
Query: 524 LYDKGYTSKEQ--KDCVGIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGE 581
+ + ++E K IF + +W I+ E
Sbjct: 888 IL---FPNEEPSWKLAKNIF----------------YMPYWMIYGEVFADQIDPPCGQNE 928
Query: 582 ELQ-------------SFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKF 628
+ +++ I+ Y +V I+L LL+A+ + +F + + ++ WKF
Sbjct: 929 TREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKF 988
Query: 629 ARAKLWLSYFDDKCTLPPPFNI 650
R +L ++ F ++ LPPP I
Sbjct: 989 QRYQLIMT-FHERPVLPPPLII 1009
>gi|154091308 transient receptor potential cation channel, subfamily
M, member 3 isoform f [Homo sapiens]
Length = 1579
Score = 46.6 bits (109), Expect = 9e-05
Identities = 68/322 (21%), Positives = 131/322 (40%), Gaps = 56/322 (17%)
Query: 347 HTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGM---IWS 403
+ P +KF + +Y +L+L N LV E +T + I Y+ L I M + S
Sbjct: 739 NAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIV--ISYIFTLGIEKMREILMS 796
Query: 404 DIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLV 463
+ +L + ++ +L+E N + L+ L++ D R D
Sbjct: 797 EPGKL-LQKVKVWLQEYWNVTDLIAILLFSVGMILRL------QDQPFRSD--------- 840
Query: 464 AEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQ 523
++ + Y+RL ++ + LGP + +G+M+ D F+ + L+VL SF +
Sbjct: 841 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 900
Query: 524 LYDKGYTSKEQ--KDCVGIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGE 581
+ + ++E K IF + +W I+ E
Sbjct: 901 IL---FPNEEPSWKLAKNIF----------------YMPYWMIYGEVFADQIDPPCGQNE 941
Query: 582 ELQ-------------SFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKF 628
+ +++ I+ Y +V I+L LL+A+ + +F + + ++ WKF
Sbjct: 942 TREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKF 1001
Query: 629 ARAKLWLSYFDDKCTLPPPFNI 650
R +L ++ F ++ LPPP I
Sbjct: 1002 QRYQLIMT-FHERPVLPPPLII 1022
>gi|154091310 transient receptor potential cation channel, subfamily
M, member 3 isoform g [Homo sapiens]
Length = 1569
Score = 46.6 bits (109), Expect = 9e-05
Identities = 68/322 (21%), Positives = 131/322 (40%), Gaps = 56/322 (17%)
Query: 347 HTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGM---IWS 403
+ P +KF + +Y +L+L N LV E +T + I Y+ L I M + S
Sbjct: 729 NAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIV--ISYIFTLGIEKMREILMS 786
Query: 404 DIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLV 463
+ +L + ++ +L+E N + L+ L++ D R D
Sbjct: 787 EPGKL-LQKVKVWLQEYWNVTDLIAILLFSVGMILRL------QDQPFRSD--------- 830
Query: 464 AEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQ 523
++ + Y+RL ++ + LGP + +G+M+ D F+ + L+VL SF +
Sbjct: 831 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 890
Query: 524 LYDKGYTSKEQ--KDCVGIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGE 581
+ + ++E K IF + +W I+ E
Sbjct: 891 IL---FPNEEPSWKLAKNIF----------------YMPYWMIYGEVFADQIDPPCGQNE 931
Query: 582 ELQ-------------SFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKF 628
+ +++ I+ Y +V I+L LL+A+ + +F + + ++ WKF
Sbjct: 932 TREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKF 991
Query: 629 ARAKLWLSYFDDKCTLPPPFNI 650
R +L ++ F ++ LPPP I
Sbjct: 992 QRYQLIMT-FHERPVLPPPLII 1012
>gi|154091320 transient receptor potential cation channel, subfamily
M, member 3 isoform a [Homo sapiens]
Length = 1554
Score = 46.6 bits (109), Expect = 9e-05
Identities = 68/322 (21%), Positives = 131/322 (40%), Gaps = 56/322 (17%)
Query: 347 HTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGM---IWS 403
+ P +KF + +Y +L+L N LV E +T + I Y+ L I M + S
Sbjct: 714 NAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIV--ISYIFTLGIEKMREILMS 771
Query: 404 DIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLV 463
+ +L + ++ +L+E N + L+ L++ D R D
Sbjct: 772 EPGKL-LQKVKVWLQEYWNVTDLIAILLFSVGMILRL------QDQPFRSD--------- 815
Query: 464 AEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQ 523
++ + Y+RL ++ + LGP + +G+M+ D F+ + L+VL SF +
Sbjct: 816 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 875
Query: 524 LYDKGYTSKEQ--KDCVGIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGE 581
+ + ++E K IF + +W I+ E
Sbjct: 876 IL---FPNEEPSWKLAKNIF----------------YMPYWMIYGEVFADQIDPPCGQNE 916
Query: 582 ELQ-------------SFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKF 628
+ +++ I+ Y +V I+L LL+A+ + +F + + ++ WKF
Sbjct: 917 TREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKF 976
Query: 629 ARAKLWLSYFDDKCTLPPPFNI 650
R +L ++ F ++ LPPP I
Sbjct: 977 QRYQLIMT-FHERPVLPPPLII 997
>gi|154091318 transient receptor potential cation channel, subfamily
M, member 3 isoform d [Homo sapiens]
Length = 1544
Score = 46.6 bits (109), Expect = 9e-05
Identities = 68/322 (21%), Positives = 131/322 (40%), Gaps = 56/322 (17%)
Query: 347 HTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGM---IWS 403
+ P +KF + +Y +L+L N LV E +T + I Y+ L I M + S
Sbjct: 704 NAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIV--ISYIFTLGIEKMREILMS 761
Query: 404 DIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLV 463
+ +L + ++ +L+E N + L+ L++ D R D
Sbjct: 762 EPGKL-LQKVKVWLQEYWNVTDLIAILLFSVGMILRL------QDQPFRSD--------- 805
Query: 464 AEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQ 523
++ + Y+RL ++ + LGP + +G+M+ D F+ + L+VL SF +
Sbjct: 806 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 865
Query: 524 LYDKGYTSKEQ--KDCVGIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGE 581
+ + ++E K IF + +W I+ E
Sbjct: 866 IL---FPNEEPSWKLAKNIF----------------YMPYWMIYGEVFADQIDPPCGQNE 906
Query: 582 ELQ-------------SFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKF 628
+ +++ I+ Y +V I+L LL+A+ + +F + + ++ WKF
Sbjct: 907 TREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKF 966
Query: 629 ARAKLWLSYFDDKCTLPPPFNI 650
R +L ++ F ++ LPPP I
Sbjct: 967 QRYQLIMT-FHERPVLPPPLII 987
>gi|154091316 transient receptor potential cation channel, subfamily
M, member 3 isoform e [Homo sapiens]
Length = 1556
Score = 46.6 bits (109), Expect = 9e-05
Identities = 68/322 (21%), Positives = 131/322 (40%), Gaps = 56/322 (17%)
Query: 347 HTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGM---IWS 403
+ P +KF + +Y +L+L N LV E +T + I Y+ L I M + S
Sbjct: 716 NAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIV--ISYIFTLGIEKMREILMS 773
Query: 404 DIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLV 463
+ +L + ++ +L+E N + L+ L++ D R D
Sbjct: 774 EPGKL-LQKVKVWLQEYWNVTDLIAILLFSVGMILRL------QDQPFRSD--------- 817
Query: 464 AEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQ 523
++ + Y+RL ++ + LGP + +G+M+ D F+ + L+VL SF +
Sbjct: 818 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 877
Query: 524 LYDKGYTSKEQ--KDCVGIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGE 581
+ + ++E K IF + +W I+ E
Sbjct: 878 IL---FPNEEPSWKLAKNIF----------------YMPYWMIYGEVFADQIDPPCGQNE 918
Query: 582 ELQ-------------SFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKF 628
+ +++ I+ Y +V I+L LL+A+ + +F + + ++ WKF
Sbjct: 919 TREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKF 978
Query: 629 ARAKLWLSYFDDKCTLPPPFNI 650
R +L ++ F ++ LPPP I
Sbjct: 979 QRYQLIMT-FHERPVLPPPLII 999
>gi|154091314 transient receptor potential cation channel, subfamily
M, member 3 isoform k [Homo sapiens]
Length = 1707
Score = 46.6 bits (109), Expect = 9e-05
Identities = 68/322 (21%), Positives = 131/322 (40%), Gaps = 56/322 (17%)
Query: 347 HTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGM---IWS 403
+ P +KF + +Y +L+L N LV E +T + I Y+ L I M + S
Sbjct: 867 NAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPSTQEWIV--ISYIFTLGIEKMREILMS 924
Query: 404 DIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLV 463
+ +L + ++ +L+E N + L+ L++ D R D
Sbjct: 925 EPGKL-LQKVKVWLQEYWNVTDLIAILLFSVGMILRL------QDQPFRSD--------- 968
Query: 464 AEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQ 523
++ + Y+RL ++ + LGP + +G+M+ D F+ + L+VL SF +
Sbjct: 969 GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQA 1028
Query: 524 LYDKGYTSKEQ--KDCVGIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGE 581
+ + ++E K IF + +W I+ E
Sbjct: 1029 IL---FPNEEPSWKLAKNIF----------------YMPYWMIYGEVFADQIDPPCGQNE 1069
Query: 582 ELQ-------------SFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKF 628
+ +++ I+ Y +V I+L LL+A+ + +F + + ++ WKF
Sbjct: 1070 TREDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKF 1129
Query: 629 ARAKLWLSYFDDKCTLPPPFNI 650
R +L ++ F ++ LPPP I
Sbjct: 1130 QRYQLIMT-FHERPVLPPPLII 1150
>gi|74315354 transient receptor potential cation channel, subfamily
V, member 1 [Homo sapiens]
Length = 839
Score = 46.2 bits (108), Expect = 1e-04
Identities = 47/253 (18%), Positives = 106/253 (41%), Gaps = 43/253 (16%)
Query: 394 ILWIIGMIWSDIKRLWYEGLEDFLE----------ESRNQLSFVMNSLYLATFALKVVAH 443
IL ++G ++ ++ G++ FL+ +S +++ F + SL++ + +H
Sbjct: 479 ILSVLGGVY-----FFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSH 533
Query: 444 NKFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDF 503
K + ++V + N+L Y R F +++ I L+D
Sbjct: 534 LK-----------EYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMI-----LRDL 577
Query: 504 GKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCV-----GIFCEQQSNDTFHSFIGTCF 558
+F+ ++++ LF F+ + L + G + G C + + +++S TC
Sbjct: 578 CRFMFVYIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPAC-RPPDSSYNSLYSTCL 636
Query: 559 ALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLI 618
LF + + + F + + V +++ Y ++ I+L +L+A++ ++ I
Sbjct: 637 ELFKFTIGMGDLE-FTENYDF-----KAVFIILLLAYVILTYILLLNMLIALMGETVNKI 690
Query: 619 ANHEDKEWKFARA 631
A WK RA
Sbjct: 691 AQESKNIWKLQRA 703
>gi|74315352 transient receptor potential cation channel, subfamily
V, member 1 [Homo sapiens]
Length = 839
Score = 46.2 bits (108), Expect = 1e-04
Identities = 47/253 (18%), Positives = 106/253 (41%), Gaps = 43/253 (16%)
Query: 394 ILWIIGMIWSDIKRLWYEGLEDFLE----------ESRNQLSFVMNSLYLATFALKVVAH 443
IL ++G ++ ++ G++ FL+ +S +++ F + SL++ + +H
Sbjct: 479 ILSVLGGVY-----FFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSH 533
Query: 444 NKFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDF 503
K + ++V + N+L Y R F +++ I L+D
Sbjct: 534 LK-----------EYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMI-----LRDL 577
Query: 504 GKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCV-----GIFCEQQSNDTFHSFIGTCF 558
+F+ ++++ LF F+ + L + G + G C + + +++S TC
Sbjct: 578 CRFMFVYIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPAC-RPPDSSYNSLYSTCL 636
Query: 559 ALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLI 618
LF + + + F + + V +++ Y ++ I+L +L+A++ ++ I
Sbjct: 637 ELFKFTIGMGDLE-FTENYDF-----KAVFIILLLAYVILTYILLLNMLIALMGETVNKI 690
Query: 619 ANHEDKEWKFARA 631
A WK RA
Sbjct: 691 AQESKNIWKLQRA 703
>gi|74315350 transient receptor potential cation channel, subfamily
V, member 1 [Homo sapiens]
Length = 839
Score = 46.2 bits (108), Expect = 1e-04
Identities = 47/253 (18%), Positives = 106/253 (41%), Gaps = 43/253 (16%)
Query: 394 ILWIIGMIWSDIKRLWYEGLEDFLE----------ESRNQLSFVMNSLYLATFALKVVAH 443
IL ++G ++ ++ G++ FL+ +S +++ F + SL++ + +H
Sbjct: 479 ILSVLGGVY-----FFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSH 533
Query: 444 NKFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDF 503
K + ++V + N+L Y R F +++ I L+D
Sbjct: 534 LK-----------EYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMI-----LRDL 577
Query: 504 GKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCV-----GIFCEQQSNDTFHSFIGTCF 558
+F+ ++++ LF F+ + L + G + G C + + +++S TC
Sbjct: 578 CRFMFVYIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPAC-RPPDSSYNSLYSTCL 636
Query: 559 ALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLI 618
LF + + + F + + V +++ Y ++ I+L +L+A++ ++ I
Sbjct: 637 ELFKFTIGMGDLE-FTENYDF-----KAVFIILLLAYVILTYILLLNMLIALMGETVNKI 690
Query: 619 ANHEDKEWKFARA 631
A WK RA
Sbjct: 691 AQESKNIWKLQRA 703
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,971,307
Number of Sequences: 37866
Number of extensions: 1157677
Number of successful extensions: 5927
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 112
Number of HSP's that attempted gapping in prelim test: 5663
Number of HSP's gapped (non-prelim): 303
length of query: 759
length of database: 18,247,518
effective HSP length: 110
effective length of query: 649
effective length of database: 14,082,258
effective search space: 9139385442
effective search space used: 9139385442
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.