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Search of human proteins with 4507509
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507509 tissue inhibitor of metalloproteinase 1 precursor
[Homo sapiens]
(207 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507509 tissue inhibitor of metalloproteinase 1 precursor [Ho... 437 e-123
gi|4507511 TIMP metallopeptidase inhibitor 2 precursor [Homo sap... 159 2e-39
gi|4507513 tissue inhibitor of metalloproteinase 3 precursor [Ho... 149 2e-36
gi|4507515 tissue inhibitor of metalloproteinase 4 precursor [Ho... 140 6e-34
gi|113722116 plexin A2 [Homo sapiens] 31 0.65
gi|34098976 marapsin 2 [Homo sapiens] 30 1.4
gi|217272863 prolyl 4-hydroxylase, alpha II subunit isoform 1 pr... 29 2.5
gi|217272861 prolyl 4-hydroxylase, alpha II subunit isoform 2 pr... 29 2.5
gi|63252893 prolyl 4-hydroxylase, alpha II subunit isoform 2 pre... 29 2.5
gi|63252891 prolyl 4-hydroxylase, alpha II subunit isoform 2 pre... 29 2.5
gi|4758868 prolyl 4-hydroxylase, alpha II subunit isoform 1 prec... 29 2.5
gi|197927160 solute carrier family 4, sodium bicarbonate cotrans... 29 3.2
gi|4507025 solute carrier family 4, sodium bicarbonate cotranspo... 29 3.2
gi|148596928 solute carrier family 4, sodium bicarbonate cotrans... 29 3.2
gi|112420992 crumbs homolog 2 [Homo sapiens] 28 7.2
gi|239755717 PREDICTED: hypothetical protein [Homo sapiens] 27 9.4
gi|7657319 ADAM-like, decysin 1 isoform 1 [Homo sapiens] 27 9.4
gi|223671932 ADAM-like, decysin 1 isoform 2 [Homo sapiens] 27 9.4
gi|223671930 ADAM-like, decysin 1 isoform 2 [Homo sapiens] 27 9.4
>gi|4507509 tissue inhibitor of metalloproteinase 1 precursor [Homo
sapiens]
Length = 207
Score = 437 bits (1124), Expect = e-123
Identities = 207/207 (100%), Positives = 207/207 (100%)
Query: 1 MAPFEPLASGILLLLWLIAPSRACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQR 60
MAPFEPLASGILLLLWLIAPSRACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQR
Sbjct: 1 MAPFEPLASGILLLLWLIAPSRACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQR 60
Query: 61 YEIKMTKMYKGFQALGDAADIRFVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHIT 120
YEIKMTKMYKGFQALGDAADIRFVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHIT
Sbjct: 61 YEIKMTKMYKGFQALGDAADIRFVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHIT 120
Query: 121 TCSFVAPWNSLSLAQRRGFTKTYTVGCEECTVFPCLSIPCKLQSGTHCLWTDQLLQGSEK 180
TCSFVAPWNSLSLAQRRGFTKTYTVGCEECTVFPCLSIPCKLQSGTHCLWTDQLLQGSEK
Sbjct: 121 TCSFVAPWNSLSLAQRRGFTKTYTVGCEECTVFPCLSIPCKLQSGTHCLWTDQLLQGSEK 180
Query: 181 GFQSRHLACLPREPGLCTWQSLRSQIA 207
GFQSRHLACLPREPGLCTWQSLRSQIA
Sbjct: 181 GFQSRHLACLPREPGLCTWQSLRSQIA 207
>gi|4507511 TIMP metallopeptidase inhibitor 2 precursor [Homo
sapiens]
Length = 220
Score = 159 bits (402), Expect = 2e-39
Identities = 85/201 (42%), Positives = 115/201 (57%), Gaps = 15/201 (7%)
Query: 7 LASGILLLLWLIAPSRACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQ-TTLYQ------ 59
LA G+LLL L+ P+ AC+C P HPQ AFCN+D+VIRAK V EV+ +Y
Sbjct: 10 LALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRI 69
Query: 60 RYEIKMTKMYKGFQALGDAADIRFVYTPAMESVCGYFHRSHNRSEEFLIAGKLQ-DGLLH 118
+YEIK KM+K G DI F+YT +VCG +E+LIAGK + DG +H
Sbjct: 70 QYEIKQIKMFK-----GPEKDIEFIYTAPSSAVCG-VSLDVGGKKEYLIAGKAEGDGKMH 123
Query: 119 ITTCSFVAPWNSLSLAQRRGFTKTYTVGCEECTVFPCLSIPCKLQSGTHCLWTDQLLQGS 178
IT C F+ PW++LS Q++ Y +GC EC + C IPC + S CLW D + + +
Sbjct: 124 ITLCDFIVPWDTLSTTQKKSLNHRYQMGC-ECKITRCPMIPCYISSPDECLWMDWVTEKN 182
Query: 179 EKGFQSRHLACLPREPGLCTW 199
G Q++ AC+ R G C W
Sbjct: 183 INGHQAKFFACIKRSDGSCAW 203
>gi|4507513 tissue inhibitor of metalloproteinase 3 precursor [Homo
sapiens]
Length = 211
Score = 149 bits (375), Expect = 2e-36
Identities = 76/195 (38%), Positives = 114/195 (58%), Gaps = 11/195 (5%)
Query: 10 GILLLL--WLIAP--SRACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQR-YEIK 64
G+++LL W + + ACTC P HPQ AFCNSD+VIRAK VG V + Y IK
Sbjct: 6 GLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYTIK 65
Query: 65 MTKMYKGFQALGDAADIRFVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSF 124
KMY+GF + +++++T A ES+CG + ++L+ G++ DG ++ C+F
Sbjct: 66 QMKMYRGFTKM---PHVQYIHTEASESLCGL--KLEVNKYQYLLTGRVYDGKMYTGLCNF 120
Query: 125 VAPWNSLSLAQRRGFTKTYTVGCEECTVFPCLSIPCKLQSGTHCLWTDQLLQGSEKGFQS 184
V W+ L+L+QR+G Y +GC C + C +PC + S CLWTD L G+QS
Sbjct: 121 VERWDQLTLSQRKGLNYRYHLGCN-CKIKSCYYLPCFVTSKNECLWTDMLSNFGYPGYQS 179
Query: 185 RHLACLPREPGLCTW 199
+H AC+ ++ G C+W
Sbjct: 180 KHYACIRQKGGYCSW 194
>gi|4507515 tissue inhibitor of metalloproteinase 4 precursor [Homo
sapiens]
Length = 224
Score = 140 bits (354), Expect = 6e-34
Identities = 74/205 (36%), Positives = 109/205 (53%), Gaps = 15/205 (7%)
Query: 6 PLASGILLL--LWLIAP---SRACTCVPPHPQTAFCNSDLVIRAKF------VGTPEVNQ 54
P S +LLL L L+ P AC+C P HPQ C+S LVIRAK + +
Sbjct: 7 PAPSWVLLLRLLALLRPPGLGEACSCAPAHPQQHICHSALVIRAKISSEKVVPASADPAD 66
Query: 55 TTLYQRYEIKMTKMYKGFQALGDAADIRFVYTPAMESVCGYFHRSHNRSEEFLIAGKLQD 114
T RYEIK KM+KGF+ + D++++YTP S+CG ++++ + L L D
Sbjct: 67 TEKMLRYEIKQIKMFKGFEKV---KDVQYIYTPFDSSLCGVKLEANSQKQYLLTGQVLSD 123
Query: 115 GLLHITTCSFVAPWNSLSLAQRRGFTKTYTVGCEECTVFPCLSIPCKLQSGTHCLWTDQL 174
G + I C+++ PW LSL QR Y + C C + C ++PC + + CLWTD L
Sbjct: 124 GKVFIHLCNYIEPWEDLSLVQRESLNHHYHLNC-GCQITTCYTVPCTISAPNECLWTDWL 182
Query: 175 LQGSEKGFQSRHLACLPREPGLCTW 199
L+ G+Q++H C+ G C+W
Sbjct: 183 LERKLYGYQAQHYVCMKHVDGTCSW 207
>gi|113722116 plexin A2 [Homo sapiens]
Length = 1894
Score = 31.2 bits (69), Expect = 0.65
Identities = 40/166 (24%), Positives = 58/166 (34%), Gaps = 19/166 (11%)
Query: 10 GILLLLWLIAPSRACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTK-- 67
G L L WL+ CT P FC D I G+ V TLY +MT
Sbjct: 379 GNLELNWLLGKDVQCTKAPVPIDDNFCGLD--INQPLGGSTPVEGLTLYTTSRDRMTSVA 436
Query: 68 --MYKGFQALGDAADIRFVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSFV 125
+Y G+ + FV T + + + ++ + L+DG + +F
Sbjct: 437 SYVYNGYSVV-------FVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGSPILRDMAFS 489
Query: 126 APWNSLSLAQRRGFTKTYTVGCEECTVF-PCLSIPCKLQSGTHCLW 170
L + R T+ CE+ T CLS HC W
Sbjct: 490 IDQRYLYVMSERQVTRVPVESCEQYTTCGECLS-----SGDPHCGW 530
>gi|34098976 marapsin 2 [Homo sapiens]
Length = 326
Score = 30.0 bits (66), Expect = 1.4
Identities = 14/32 (43%), Positives = 18/32 (56%)
Query: 1 MAPFEPLASGILLLLWLIAPSRACTCVPPHPQ 32
M P P A G+LLLL ++AP R V P+
Sbjct: 8 MGPLGPSALGLLLLLLVVAPPRVAALVHRQPE 39
>gi|217272863 prolyl 4-hydroxylase, alpha II subunit isoform 1
precursor [Homo sapiens]
Length = 535
Score = 29.3 bits (64), Expect = 2.5
Identities = 20/51 (39%), Positives = 26/51 (50%), Gaps = 3/51 (5%)
Query: 151 TVFPCLSIPCKLQSGTHCLWTDQLLQGSEKGFQSRHLACLPREPGLCTWQS 201
TVFP L + GT W + LL+ E +++RH AC P G C W S
Sbjct: 467 TVFPDLGAAIWPKKGTAVFWYN-LLRSGEGDYRTRHAAC-PVLVG-CKWVS 514
>gi|217272861 prolyl 4-hydroxylase, alpha II subunit isoform 2
precursor [Homo sapiens]
Length = 533
Score = 29.3 bits (64), Expect = 2.5
Identities = 20/51 (39%), Positives = 26/51 (50%), Gaps = 3/51 (5%)
Query: 151 TVFPCLSIPCKLQSGTHCLWTDQLLQGSEKGFQSRHLACLPREPGLCTWQS 201
TVFP L + GT W + LL+ E +++RH AC P G C W S
Sbjct: 465 TVFPDLGAAIWPKKGTAVFWYN-LLRSGEGDYRTRHAAC-PVLVG-CKWVS 512
>gi|63252893 prolyl 4-hydroxylase, alpha II subunit isoform 2
precursor [Homo sapiens]
Length = 533
Score = 29.3 bits (64), Expect = 2.5
Identities = 20/51 (39%), Positives = 26/51 (50%), Gaps = 3/51 (5%)
Query: 151 TVFPCLSIPCKLQSGTHCLWTDQLLQGSEKGFQSRHLACLPREPGLCTWQS 201
TVFP L + GT W + LL+ E +++RH AC P G C W S
Sbjct: 465 TVFPDLGAAIWPKKGTAVFWYN-LLRSGEGDYRTRHAAC-PVLVG-CKWVS 512
>gi|63252891 prolyl 4-hydroxylase, alpha II subunit isoform 2
precursor [Homo sapiens]
Length = 533
Score = 29.3 bits (64), Expect = 2.5
Identities = 20/51 (39%), Positives = 26/51 (50%), Gaps = 3/51 (5%)
Query: 151 TVFPCLSIPCKLQSGTHCLWTDQLLQGSEKGFQSRHLACLPREPGLCTWQS 201
TVFP L + GT W + LL+ E +++RH AC P G C W S
Sbjct: 465 TVFPDLGAAIWPKKGTAVFWYN-LLRSGEGDYRTRHAAC-PVLVG-CKWVS 512
>gi|4758868 prolyl 4-hydroxylase, alpha II subunit isoform 1
precursor [Homo sapiens]
Length = 535
Score = 29.3 bits (64), Expect = 2.5
Identities = 20/51 (39%), Positives = 26/51 (50%), Gaps = 3/51 (5%)
Query: 151 TVFPCLSIPCKLQSGTHCLWTDQLLQGSEKGFQSRHLACLPREPGLCTWQS 201
TVFP L + GT W + LL+ E +++RH AC P G C W S
Sbjct: 467 TVFPDLGAAIWPKKGTAVFWYN-LLRSGEGDYRTRHAAC-PVLVG-CKWVS 514
>gi|197927160 solute carrier family 4, sodium bicarbonate
cotransporter, member 4 isoform 3 [Homo sapiens]
Length = 1094
Score = 28.9 bits (63), Expect = 3.2
Identities = 11/36 (30%), Positives = 21/36 (58%), Gaps = 2/36 (5%)
Query: 23 ACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLY 58
+CTCVPP P ++D + +++ P ++ T +Y
Sbjct: 626 SCTCVPPDPANISISNDTTLAPEYL--PTMSSTDMY 659
>gi|4507025 solute carrier family 4, sodium bicarbonate
cotransporter, member 4 isoform 2 [Homo sapiens]
Length = 1035
Score = 28.9 bits (63), Expect = 3.2
Identities = 11/36 (30%), Positives = 21/36 (58%), Gaps = 2/36 (5%)
Query: 23 ACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLY 58
+CTCVPP P ++D + +++ P ++ T +Y
Sbjct: 582 SCTCVPPDPANISISNDTTLAPEYL--PTMSSTDMY 615
>gi|148596928 solute carrier family 4, sodium bicarbonate
cotransporter, member 4 isoform 1 [Homo sapiens]
Length = 1079
Score = 28.9 bits (63), Expect = 3.2
Identities = 11/36 (30%), Positives = 21/36 (58%), Gaps = 2/36 (5%)
Query: 23 ACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLY 58
+CTCVPP P ++D + +++ P ++ T +Y
Sbjct: 626 SCTCVPPDPANISISNDTTLAPEYL--PTMSSTDMY 659
>gi|112420992 crumbs homolog 2 [Homo sapiens]
Length = 1285
Score = 27.7 bits (60), Expect = 7.2
Identities = 17/35 (48%), Positives = 20/35 (57%), Gaps = 1/35 (2%)
Query: 5 EPLASGILLLLWLIAPSRACTCVPPHPQTAFCNSD 39
+ LAS +LLLLW A S VP P +A C SD
Sbjct: 12 QALASVLLLLLWAPALSLLAGTVPSEPPSA-CASD 45
>gi|239755717 PREDICTED: hypothetical protein [Homo sapiens]
Length = 187
Score = 27.3 bits (59), Expect = 9.4
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 6 PLASGILLLLWLIAPSRACTCVPPHPQTAFCNS 38
P SG LLLL L+ P PP P +F +S
Sbjct: 109 PCLSGCLLLLLLLTPFLLLXLPPPPPPPSFSSS 141
>gi|7657319 ADAM-like, decysin 1 isoform 1 [Homo sapiens]
Length = 470
Score = 27.3 bits (59), Expect = 9.4
Identities = 10/21 (47%), Positives = 14/21 (66%)
Query: 148 EECTVFPCLSIPCKLQSGTHC 168
+ECT C ++ CKL+ GT C
Sbjct: 440 KECTNLCCEALTCKLKPGTDC 460
>gi|223671932 ADAM-like, decysin 1 isoform 2 [Homo sapiens]
Length = 391
Score = 27.3 bits (59), Expect = 9.4
Identities = 10/21 (47%), Positives = 14/21 (66%)
Query: 148 EECTVFPCLSIPCKLQSGTHC 168
+ECT C ++ CKL+ GT C
Sbjct: 361 KECTNLCCEALTCKLKPGTDC 381
>gi|223671930 ADAM-like, decysin 1 isoform 2 [Homo sapiens]
Length = 391
Score = 27.3 bits (59), Expect = 9.4
Identities = 10/21 (47%), Positives = 14/21 (66%)
Query: 148 EECTVFPCLSIPCKLQSGTHC 168
+ECT C ++ CKL+ GT C
Sbjct: 361 KECTNLCCEALTCKLKPGTDC 381
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.137 0.450
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,705,279
Number of Sequences: 37866
Number of extensions: 376708
Number of successful extensions: 973
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 955
Number of HSP's gapped (non-prelim): 20
length of query: 207
length of database: 18,247,518
effective HSP length: 98
effective length of query: 109
effective length of database: 14,536,650
effective search space: 1584494850
effective search space used: 1584494850
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.