BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4507467 transforming growth factor, beta-induced, 68kDa precursor [Homo sapiens] (683 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4507467 transforming growth factor, beta-induced, 68kDa precu... 1346 0.0 gi|209863011 periostin, osteoblast specific factor isoform 3 [Ho... 598 e-171 gi|209863034 periostin, osteoblast specific factor isoform 4 [Ho... 597 e-171 gi|209862911 periostin, osteoblast specific factor isoform 2 [Ho... 597 e-171 gi|209862907 periostin, osteoblast specific factor isoform 1 [Ho... 597 e-170 gi|61743980 stabilin 2 precursor [Homo sapiens] 79 1e-14 gi|61743978 stabilin 1 precursor [Homo sapiens] 67 4e-11 gi|39725938 polymerase (RNA) III (DNA directed) polypeptide A, 1... 34 0.39 gi|118572599 formin homology 2 domain containing 1 [Homo sapiens] 31 3.3 gi|227499621 solute carrier family 27 (fatty acid transporter), ... 30 5.7 gi|227499619 solute carrier family 27 (fatty acid transporter), ... 30 5.7 gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi... 30 5.7 gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 30 5.7 gi|154426300 hypothetical protein LOC54934 [Homo sapiens] 30 5.7 gi|223941923 OTU domain containing 1 [Homo sapiens] 30 9.6 gi|88900507 protein arginine methyltransferase 5 isoform b [Homo... 30 9.6 gi|20070220 protein arginine methyltransferase 5 isoform a [Homo... 30 9.6 >gi|4507467 transforming growth factor, beta-induced, 68kDa precursor [Homo sapiens] Length = 683 Score = 1346 bits (3483), Expect = 0.0 Identities = 683/683 (100%), Positives = 683/683 (100%) Query: 1 MALFVRLLALALALALGPAATLAGPAKSPYQLVLQHSRLRGRQHGPNVCAVQKVIGTNRK 60 MALFVRLLALALALALGPAATLAGPAKSPYQLVLQHSRLRGRQHGPNVCAVQKVIGTNRK Sbjct: 1 MALFVRLLALALALALGPAATLAGPAKSPYQLVLQHSRLRGRQHGPNVCAVQKVIGTNRK 60 Query: 61 YFTNCKQWYQRKICGKSTVISYECCPGYEKVPGEKGCPAALPLSNLYETLGVVGSTTTQL 120 YFTNCKQWYQRKICGKSTVISYECCPGYEKVPGEKGCPAALPLSNLYETLGVVGSTTTQL Sbjct: 61 YFTNCKQWYQRKICGKSTVISYECCPGYEKVPGEKGCPAALPLSNLYETLGVVGSTTTQL 120 Query: 121 YTDRTEKLRPEMEGPGSFTIFAPSNEAWASLPAEVLDSLVSNVNIELLNALRYHMVGRRV 180 YTDRTEKLRPEMEGPGSFTIFAPSNEAWASLPAEVLDSLVSNVNIELLNALRYHMVGRRV Sbjct: 121 YTDRTEKLRPEMEGPGSFTIFAPSNEAWASLPAEVLDSLVSNVNIELLNALRYHMVGRRV 180 Query: 181 LTDELKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVISTIT 240 LTDELKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVISTIT Sbjct: 181 LTDELKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVISTIT 240 Query: 241 NNIQQIIEIEDTFETLRAAVAASGLNTMLEGNGQYTLLAPTNEAFEKIPSETLNRILGDP 300 NNIQQIIEIEDTFETLRAAVAASGLNTMLEGNGQYTLLAPTNEAFEKIPSETLNRILGDP Sbjct: 241 NNIQQIIEIEDTFETLRAAVAASGLNTMLEGNGQYTLLAPTNEAFEKIPSETLNRILGDP 300 Query: 301 EALRDLLNNHILKSAMCAEAIVAGLSVETLEGTTLEVGCSGDMLTINGKAIISNKDILAT 360 EALRDLLNNHILKSAMCAEAIVAGLSVETLEGTTLEVGCSGDMLTINGKAIISNKDILAT Sbjct: 301 EALRDLLNNHILKSAMCAEAIVAGLSVETLEGTTLEVGCSGDMLTINGKAIISNKDILAT 360 Query: 361 NGVIHYIDELLIPDSAKTLFELAAESDVSTAIDLFRQAGLGNHLSGSERLTLLAPLNSVF 420 NGVIHYIDELLIPDSAKTLFELAAESDVSTAIDLFRQAGLGNHLSGSERLTLLAPLNSVF Sbjct: 361 NGVIHYIDELLIPDSAKTLFELAAESDVSTAIDLFRQAGLGNHLSGSERLTLLAPLNSVF 420 Query: 421 KDGTPPIDAHTRNLLRNHIIKDQLASKYLYHGQTLETLGGKKLRVFVYRNSLCIENSCIA 480 KDGTPPIDAHTRNLLRNHIIKDQLASKYLYHGQTLETLGGKKLRVFVYRNSLCIENSCIA Sbjct: 421 KDGTPPIDAHTRNLLRNHIIKDQLASKYLYHGQTLETLGGKKLRVFVYRNSLCIENSCIA 480 Query: 481 AHDKRGRYGTLFTMDRVLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLTETLNREGVYTVF 540 AHDKRGRYGTLFTMDRVLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLTETLNREGVYTVF Sbjct: 481 AHDKRGRYGTLFTMDRVLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLTETLNREGVYTVF 540 Query: 541 APTNEAFRALPPRERSRLLGDAKELANILKYHIGDEILVSGGIGALVRLKSLQGDKLEVS 600 APTNEAFRALPPRERSRLLGDAKELANILKYHIGDEILVSGGIGALVRLKSLQGDKLEVS Sbjct: 541 APTNEAFRALPPRERSRLLGDAKELANILKYHIGDEILVSGGIGALVRLKSLQGDKLEVS 600 Query: 601 LKNNVVSVNKEPVAEPDIMATNGVVHVITNVLQPPANRPQERGDELADSALEIFKQASAF 660 LKNNVVSVNKEPVAEPDIMATNGVVHVITNVLQPPANRPQERGDELADSALEIFKQASAF Sbjct: 601 LKNNVVSVNKEPVAEPDIMATNGVVHVITNVLQPPANRPQERGDELADSALEIFKQASAF 660 Query: 661 SRASQRSVRLAPVYQKLLERMKH 683 SRASQRSVRLAPVYQKLLERMKH Sbjct: 661 SRASQRSVRLAPVYQKLLERMKH 683 >gi|209863011 periostin, osteoblast specific factor isoform 3 [Homo sapiens] Length = 781 Score = 598 bits (1543), Expect = e-171 Identities = 312/686 (45%), Positives = 440/686 (64%), Gaps = 13/686 (1%) Query: 1 MALFVRLLALALALALGPAATLAGPAKSPYQLVLQHSRLRGRQHGPNVCAVQKVIGTNRK 60 M F+ + +L L L + P A + Y +L HSR+RGR GPNVCA+Q+++GT +K Sbjct: 1 MIPFLPMFSLLLLLIVNPIN-----ANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKK 55 Query: 61 YFTNCKQWYQRKICGKSTVISYECCPGYEKVPGEKGCPAALPLSNLYETLGVVGSTTTQL 120 YF+ CK WY++ ICG+ T + YECCPGY ++ G KGCPA LP+ ++Y TLG+VG+TTTQ Sbjct: 56 YFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQR 115 Query: 121 YTDRTEKLRPEMEGPGSFTIFAPSNEAWASLPAEVLDSLVSNVNIELLNALRYHMVGRRV 180 Y+D + KLR E+EG GSFT FAPSNEAW +L +++ L SNVN+ELLNAL HM+ +R+ Sbjct: 116 YSDAS-KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRM 174 Query: 181 LTDELKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVISTIT 240 LT +LK+GM + SMY N + I+HYPNG+VTVNCAR++ + ATNGVVH+ID+V++ I Sbjct: 175 LTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIG 234 Query: 241 NNIQQIIEIEDTFETLRAAVAASGLNTMLEGNGQYTLLAPTNEAFEKIPSETLNRILGDP 300 +IQ IE ED + RAA S + L +G +TL APTNEAFEK+P L RI+GD Sbjct: 235 TSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDK 294 Query: 301 EALRDLLNNHILKSAMCAEAIVAGLSVETLEGTTLEVGCSGDMLTINGKAIISNKDILAT 360 A L+ HIL + C+E+I+ G ETLEG T+E+GC GD +T+NG +++ KDI+ Sbjct: 295 VASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTN 354 Query: 361 NGVIHYIDELLIPDSAKTLFELAAESDVSTAIDLFRQAGLGNHLSGSERLTLLAPLNSVF 420 NGVIH ID++LIPDSAK + ELA + +T DL Q GL + L TLLAP+N+ F Sbjct: 355 NGVIHLIDQVLIPDSAKQVIELAGKQQ-TTFTDLVAQLGLASALRPDGEYTLLAPVNNAF 413 Query: 421 KDGTPPIDAHTRNL-LRNHIIKDQLASKYLYHGQTLETLGGKKLRVFVYRNSLCIENSCI 479 D T +D L L+NHI+K ++ LY+GQ LET+GGK+LRVFVYR ++CIENSC+ Sbjct: 414 SDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCM 473 Query: 480 AAHDKRGRYGTLFTMDRVLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLTETLNREGVYTV 539 K+GR G + ++ P ++ + LK D RFS ++ +++A L E L + G +T+ Sbjct: 474 EKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTL 533 Query: 540 FAPTNEAFRALPPRERSRLLGDAKELANILKYHIGDEILVSGGI--GALVRLKSLQGDKL 597 F PTN+AF+ + E+ L+ D L NI+ YH+ + + G G LK+ QG K+ Sbjct: 534 FVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKI 593 Query: 598 EVSLKNNVVSVNKEPVAEPDIMATNGVVHVITNVLQPPANRPQERGDELADSALEIFKQA 657 + N+ + VN+ E DIM TNGV+HV+ +L PA+ P D+L + ++ K Sbjct: 594 FLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLY-PADTP-VGNDQLLEILNKLIKYI 651 Query: 658 S-AFSRASQRSVRLAPVYQKLLERMK 682 F R S VY+ L ++K Sbjct: 652 QIKFVRGSTFKEIPVTVYRPTLTKVK 677 >gi|209863034 periostin, osteoblast specific factor isoform 4 [Homo sapiens] Length = 751 Score = 597 bits (1540), Expect = e-171 Identities = 310/684 (45%), Positives = 440/684 (64%), Gaps = 13/684 (1%) Query: 1 MALFVRLLALALALALGPAATLAGPAKSPYQLVLQHSRLRGRQHGPNVCAVQKVIGTNRK 60 M F+ + +L L L + P A + Y +L HSR+RGR GPNVCA+Q+++GT +K Sbjct: 1 MIPFLPMFSLLLLLIVNPIN-----ANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKK 55 Query: 61 YFTNCKQWYQRKICGKSTVISYECCPGYEKVPGEKGCPAALPLSNLYETLGVVGSTTTQL 120 YF+ CK WY++ ICG+ T + YECCPGY ++ G KGCPA LP+ ++Y TLG+VG+TTTQ Sbjct: 56 YFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQR 115 Query: 121 YTDRTEKLRPEMEGPGSFTIFAPSNEAWASLPAEVLDSLVSNVNIELLNALRYHMVGRRV 180 Y+D + KLR E+EG GSFT FAPSNEAW +L +++ L SNVN+ELLNAL HM+ +R+ Sbjct: 116 YSDAS-KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRM 174 Query: 181 LTDELKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVISTIT 240 LT +LK+GM + SMY N + I+HYPNG+VTVNCAR++ + ATNGVVH+ID+V++ I Sbjct: 175 LTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIG 234 Query: 241 NNIQQIIEIEDTFETLRAAVAASGLNTMLEGNGQYTLLAPTNEAFEKIPSETLNRILGDP 300 +IQ IE ED + RAA S + L +G +TL APTNEAFEK+P L RI+GD Sbjct: 235 TSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDK 294 Query: 301 EALRDLLNNHILKSAMCAEAIVAGLSVETLEGTTLEVGCSGDMLTINGKAIISNKDILAT 360 A L+ HIL + C+E+I+ G ETLEG T+E+GC GD +T+NG +++ KDI+ Sbjct: 295 VASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTN 354 Query: 361 NGVIHYIDELLIPDSAKTLFELAAESDVSTAIDLFRQAGLGNHLSGSERLTLLAPLNSVF 420 NGVIH ID++LIPDSAK + ELA + +T DL Q GL + L TLLAP+N+ F Sbjct: 355 NGVIHLIDQVLIPDSAKQVIELAGKQQ-TTFTDLVAQLGLASALRPDGEYTLLAPVNNAF 413 Query: 421 KDGTPPIDAHTRNL-LRNHIIKDQLASKYLYHGQTLETLGGKKLRVFVYRNSLCIENSCI 479 D T +D L L+NHI+K ++ LY+GQ LET+GGK+LRVFVYR ++CIENSC+ Sbjct: 414 SDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCM 473 Query: 480 AAHDKRGRYGTLFTMDRVLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLTETLNREGVYTV 539 K+GR G + ++ P ++ + LK D RFS ++ +++A L E L + G +T+ Sbjct: 474 EKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTL 533 Query: 540 FAPTNEAFRALPPRERSRLLGDAKELANILKYHIGDEILVSGGI--GALVRLKSLQGDKL 597 F PTN+AF+ + E+ L+ D L NI+ YH+ + + G G LK+ QG K+ Sbjct: 534 FVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKI 593 Query: 598 EVSLKNNVVSVNKEPVAEPDIMATNGVVHVITNVLQPPANRPQERGDELADSALEIFKQA 657 + N+ + VN+ E DIM TNGV+HV+ +L PA+ P D+L + ++ K Sbjct: 594 FLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLY-PADTP-VGNDQLLEILNKLIKYI 651 Query: 658 S-AFSRASQRSVRLAPVYQKLLER 680 F R S VY+ ++++ Sbjct: 652 QIKFVRGSTFKEIPVTVYKPIIKK 675 >gi|209862911 periostin, osteoblast specific factor isoform 2 [Homo sapiens] Length = 779 Score = 597 bits (1540), Expect = e-171 Identities = 310/684 (45%), Positives = 440/684 (64%), Gaps = 13/684 (1%) Query: 1 MALFVRLLALALALALGPAATLAGPAKSPYQLVLQHSRLRGRQHGPNVCAVQKVIGTNRK 60 M F+ + +L L L + P A + Y +L HSR+RGR GPNVCA+Q+++GT +K Sbjct: 1 MIPFLPMFSLLLLLIVNPIN-----ANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKK 55 Query: 61 YFTNCKQWYQRKICGKSTVISYECCPGYEKVPGEKGCPAALPLSNLYETLGVVGSTTTQL 120 YF+ CK WY++ ICG+ T + YECCPGY ++ G KGCPA LP+ ++Y TLG+VG+TTTQ Sbjct: 56 YFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQR 115 Query: 121 YTDRTEKLRPEMEGPGSFTIFAPSNEAWASLPAEVLDSLVSNVNIELLNALRYHMVGRRV 180 Y+D + KLR E+EG GSFT FAPSNEAW +L +++ L SNVN+ELLNAL HM+ +R+ Sbjct: 116 YSDAS-KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRM 174 Query: 181 LTDELKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVISTIT 240 LT +LK+GM + SMY N + I+HYPNG+VTVNCAR++ + ATNGVVH+ID+V++ I Sbjct: 175 LTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIG 234 Query: 241 NNIQQIIEIEDTFETLRAAVAASGLNTMLEGNGQYTLLAPTNEAFEKIPSETLNRILGDP 300 +IQ IE ED + RAA S + L +G +TL APTNEAFEK+P L RI+GD Sbjct: 235 TSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDK 294 Query: 301 EALRDLLNNHILKSAMCAEAIVAGLSVETLEGTTLEVGCSGDMLTINGKAIISNKDILAT 360 A L+ HIL + C+E+I+ G ETLEG T+E+GC GD +T+NG +++ KDI+ Sbjct: 295 VASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTN 354 Query: 361 NGVIHYIDELLIPDSAKTLFELAAESDVSTAIDLFRQAGLGNHLSGSERLTLLAPLNSVF 420 NGVIH ID++LIPDSAK + ELA + +T DL Q GL + L TLLAP+N+ F Sbjct: 355 NGVIHLIDQVLIPDSAKQVIELAGKQQ-TTFTDLVAQLGLASALRPDGEYTLLAPVNNAF 413 Query: 421 KDGTPPIDAHTRNL-LRNHIIKDQLASKYLYHGQTLETLGGKKLRVFVYRNSLCIENSCI 479 D T +D L L+NHI+K ++ LY+GQ LET+GGK+LRVFVYR ++CIENSC+ Sbjct: 414 SDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCM 473 Query: 480 AAHDKRGRYGTLFTMDRVLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLTETLNREGVYTV 539 K+GR G + ++ P ++ + LK D RFS ++ +++A L E L + G +T+ Sbjct: 474 EKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTL 533 Query: 540 FAPTNEAFRALPPRERSRLLGDAKELANILKYHIGDEILVSGGI--GALVRLKSLQGDKL 597 F PTN+AF+ + E+ L+ D L NI+ YH+ + + G G LK+ QG K+ Sbjct: 534 FVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKI 593 Query: 598 EVSLKNNVVSVNKEPVAEPDIMATNGVVHVITNVLQPPANRPQERGDELADSALEIFKQA 657 + N+ + VN+ E DIM TNGV+HV+ +L PA+ P D+L + ++ K Sbjct: 594 FLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLY-PADTP-VGNDQLLEILNKLIKYI 651 Query: 658 S-AFSRASQRSVRLAPVYQKLLER 680 F R S VY+ ++++ Sbjct: 652 QIKFVRGSTFKEIPVTVYKPIIKK 675 >gi|209862907 periostin, osteoblast specific factor isoform 1 [Homo sapiens] Length = 836 Score = 597 bits (1539), Expect = e-170 Identities = 300/637 (47%), Positives = 420/637 (65%), Gaps = 10/637 (1%) Query: 1 MALFVRLLALALALALGPAATLAGPAKSPYQLVLQHSRLRGRQHGPNVCAVQKVIGTNRK 60 M F+ + +L L L + P A + Y +L HSR+RGR GPNVCA+Q+++GT +K Sbjct: 1 MIPFLPMFSLLLLLIVNPIN-----ANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKK 55 Query: 61 YFTNCKQWYQRKICGKSTVISYECCPGYEKVPGEKGCPAALPLSNLYETLGVVGSTTTQL 120 YF+ CK WY++ ICG+ T + YECCPGY ++ G KGCPA LP+ ++Y TLG+VG+TTTQ Sbjct: 56 YFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQR 115 Query: 121 YTDRTEKLRPEMEGPGSFTIFAPSNEAWASLPAEVLDSLVSNVNIELLNALRYHMVGRRV 180 Y+D + KLR E+EG GSFT FAPSNEAW +L +++ L SNVN+ELLNAL HM+ +R+ Sbjct: 116 YSDAS-KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRM 174 Query: 181 LTDELKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVISTIT 240 LT +LK+GM + SMY N + I+HYPNG+VTVNCAR++ + ATNGVVH+ID+V++ I Sbjct: 175 LTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIG 234 Query: 241 NNIQQIIEIEDTFETLRAAVAASGLNTMLEGNGQYTLLAPTNEAFEKIPSETLNRILGDP 300 +IQ IE ED + RAA S + L +G +TL APTNEAFEK+P L RI+GD Sbjct: 235 TSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDK 294 Query: 301 EALRDLLNNHILKSAMCAEAIVAGLSVETLEGTTLEVGCSGDMLTINGKAIISNKDILAT 360 A L+ HIL + C+E+I+ G ETLEG T+E+GC GD +T+NG +++ KDI+ Sbjct: 295 VASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTN 354 Query: 361 NGVIHYIDELLIPDSAKTLFELAAESDVSTAIDLFRQAGLGNHLSGSERLTLLAPLNSVF 420 NGVIH ID++LIPDSAK + ELA + +T DL Q GL + L TLLAP+N+ F Sbjct: 355 NGVIHLIDQVLIPDSAKQVIELAGKQQ-TTFTDLVAQLGLASALRPDGEYTLLAPVNNAF 413 Query: 421 KDGTPPIDAHTRNL-LRNHIIKDQLASKYLYHGQTLETLGGKKLRVFVYRNSLCIENSCI 479 D T +D L L+NHI+K ++ LY+GQ LET+GGK+LRVFVYR ++CIENSC+ Sbjct: 414 SDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCM 473 Query: 480 AAHDKRGRYGTLFTMDRVLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLTETLNREGVYTV 539 K+GR G + ++ P ++ + LK D RFS ++ +++A L E L + G +T+ Sbjct: 474 EKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTL 533 Query: 540 FAPTNEAFRALPPRERSRLLGDAKELANILKYHIGDEILVSGGI--GALVRLKSLQGDKL 597 F PTN+AF+ + E+ L+ D L NI+ YH+ + + G G LK+ QG K+ Sbjct: 534 FVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKI 593 Query: 598 EVSLKNNVVSVNKEPVAEPDIMATNGVVHVITNVLQP 634 + N+ + VN+ E DIM TNGV+HV+ +L P Sbjct: 594 FLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYP 630 Score = 102 bits (253), Expect = 2e-21 Identities = 101/399 (25%), Positives = 174/399 (43%), Gaps = 33/399 (8%) Query: 262 ASGLNTMLEGNGQYTLLAPTNEAFEKIPSETLNRILGDPEA-LRDLLNNHILKSAMCAEA 320 AS L +EG G +T AP+NEA++ + S+ + + L + L++H++ M + Sbjct: 119 ASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKD 178 Query: 321 IVAGLSVETLE---GTTLEVGCSGDMLTINGKAIISNKDILATNGVIHYIDELLIPDSAK 377 + G+ + ++ G + +G ++T+N II I ATNGV+H ID +L Sbjct: 179 LKNGMIIPSMYNNLGLFINHYPNG-VVTVNCARIIHGNQI-ATNGVVHVIDRVLTQIGTS 236 Query: 378 TLFELAAESDVSTAIDLFRQAGLGNH----LSGSERLTLLAPLNSVFKDGTPPI------ 427 + AE D+S+ FR A + + L TL AP N F+ + Sbjct: 237 IQDFIEAEDDLSS----FRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMG 292 Query: 428 -DAHTRNLLRNHIIKDQLASKYLYHGQTLETLGGKKLRVFVYRNSLCIEN-SCIAAHDKR 485 + L++ HI+ S+ + G ETL G + + +S+ + + D Sbjct: 293 DKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIV 352 Query: 486 GRYGTLFTMDRVLTPPMGTVMDVLKGDNR--FSMLVAAIQSAGLTETLNREGVYTVFAPT 543 G + +D+VL P + L G + F+ LVA + GL L +G YT+ AP Sbjct: 353 TNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQL---GLASALRPDGEYTLLAPV 409 Query: 544 NEAFRALPPRERSRLLGDAKELANILKYHIGDEILVSGGIGALVRLKSLQGDKLEVSLKN 603 N AF RLL + +ILK +G L +G I L+++ G +L V + Sbjct: 410 NNAFSDDTLSMDQRLLKLILQ-NHILKVKVGLNELYNGQI-----LETIGGKQLRVFVYR 463 Query: 604 NVVSVNKEPVAEPDIMATNGVVHVITNVLQPPANRPQER 642 V + + + NG +H+ +++P E+ Sbjct: 464 TAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEK 502 >gi|61743980 stabilin 2 precursor [Homo sapiens] Length = 2551 Score = 79.0 bits (193), Expect = 1e-14 Identities = 82/306 (26%), Positives = 142/306 (46%), Gaps = 34/306 (11%) Query: 117 TTQLYTDRTEKLRPEMEGPGSFTIFAPSNEAWASLPAEVLDSLVSNVNIELLNALRYHMV 176 T+Q + E ++ GPG FT+FAP + A+ A V D + + LRYH+V Sbjct: 1609 TSQYFFQLQEHFVKDLVGPGPFTVFAPLSAAFDE-EARVKDWDKYGL---MPQVLRYHVV 1664 Query: 177 G-RRVLTDELKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKV 235 ++L + LK TS+ Q I I + + N A+++ +D +TNG+VH+IDK+ Sbjct: 1665 ACHQLLLENLKLISNATSL-QGEPIVISVSQSTVYINNKAKIISSDIISTNGIVHIIDKL 1723 Query: 236 IS------TITNNIQQIIEIEDTFET------LRAAVAASGLNTMLEG--NGQYTLLAPT 281 +S T +N +I++ T T + SGL +++ + TL PT Sbjct: 1724 LSPKNLLITPKDNSGRILQNLTTLATNNGYIKFSNLIQDSGLLSVITDPIHTPVTLFWPT 1783 Query: 282 NEAFEKIPSETLNRILG--DPEALRDLLNNHILKSA-MCAEAIVAGLSVETLEGTTLEVG 338 ++A +P+E + + + + L++ L H+++ A + A + + +TL+G+ L V Sbjct: 1784 DQALHALPAEQQDFLFNQDNKDKLKEYLKFHVIRDAKVLAVDLPTSTAWKTLQGSELSVK 1843 Query: 339 CS-----GDMLTINGKAIISNKDILATNGVIHYIDELLIPDSAKTLFELAAESDVSTAID 393 C GD+ I +++L GV + ID LLI + L D T D Sbjct: 1844 CGAGRDIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLIDPT------LGGRCDTFTTFD 1897 Query: 394 LFRQAG 399 + G Sbjct: 1898 ASGECG 1903 Score = 68.9 bits (167), Expect = 1e-11 Identities = 65/257 (25%), Positives = 120/257 (46%), Gaps = 23/257 (8%) Query: 128 LRPEMEGPGSFTIFAPSNEAWASLPAEVLDSLVSNVNIELLNALRYHMV-GRRVLTD--E 184 L+P + + T+ PS +A + + +S NI L ++YHM+ G + D Sbjct: 1019 LQPTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPAL--IKYHMLLGTYRVADLQT 1076 Query: 185 LKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVI-------S 237 L L + Q + + + +G +T+ A ++ D+ ATNGV+H+I+KV+ Sbjct: 1077 LSSSDMLATSLQGNFLHLAKV-DGNITIEGASIVDGDNAATNGVIHIINKVLVPQRRLTG 1135 Query: 238 TITNNIQQIIEIEDTFETLRAAVAASGLNTMLEGNGQYTLLAPTNEAFEKIPSETLNRIL 297 ++ N + ++ ++ D + R + L +E YT+ AP N A E E ++L Sbjct: 1136 SLPNLLMRLEQMPD-YSIFRGYIIQYNLANAIEAADAYTVFAPNNNAIENYIRE--KKVL 1192 Query: 298 GDPEALRDLLNNH-ILKSAMCAEAIVAGLSVETLEGTT--LEVGCSGDMLTINGKAIISN 354 E D+L H +L+ + + G+ ET+ G + L D L +N +A I+ Sbjct: 1193 SLEE---DVLRYHVVLEEKLLKNDLHNGMHRETMLGFSYFLSFFLHNDQLYVN-EAPINY 1248 Query: 355 KDILATNGVIHYIDELL 371 ++ GVIH + ++L Sbjct: 1249 TNVATDKGVIHGLGKVL 1265 Score = 57.4 bits (137), Expect = 4e-08 Identities = 63/272 (23%), Positives = 119/272 (43%), Gaps = 23/272 (8%) Query: 263 SGLNTMLEGNGQYTLLAPTNEAFEKIPSETLNRILGDPEALRDLLNNHIL----KSAMCA 318 + L L T+L P+ +A E + + + L + L+ H+L + A Sbjct: 1017 ASLQPTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSN-IPALIKYHMLLGTYRVADLQ 1075 Query: 319 EAIVAGLSVETLEGTTLEVGCSGDMLTINGKAIISNKDILATNGVIHYIDELLIPDSAKT 378 + + +L+G L + +TI G +I+ D ATNGVIH I+++L+P T Sbjct: 1076 TLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVDG-DNAATNGVIHIINKVLVPQRRLT 1134 Query: 379 ------LFELAAESDVSTAIDLFRQAGLGNHLSGSERLTLLAPLNSVFKD--GTPPIDAH 430 L L D S Q L N + ++ T+ AP N+ ++ + + Sbjct: 1135 GSLPNLLMRLEQMPDYSIFRGYIIQYNLANAIEAADAYTVFAPNNNAIENYIREKKVLSL 1194 Query: 431 TRNLLRNHII-KDQLASKYLYHGQTLETLGGKKLRVFVYRNSLCIENSCIAAHDKRGRYG 489 ++LR H++ +++L L++G ET+ G F Y S + N + ++ Y Sbjct: 1195 EEDVLRYHVVLEEKLLKNDLHNGMHRETMLG-----FSYFLSFFLHNDQLYVNEAPINYT 1249 Query: 490 TLFTMDRVLTPPMGTVMDVLKG--DNRFSMLV 519 + T D+ + +G V+++ K DN + ++ Sbjct: 1250 NVAT-DKGVIHGLGKVLEIQKNRCDNNDTTII 1280 Score = 50.4 bits (119), Expect = 5e-06 Identities = 39/173 (22%), Positives = 84/173 (48%), Gaps = 14/173 (8%) Query: 216 RLLKADHHATNGVVHLIDKVISTI-----TNNIQQIIE-IEDTFETLRAAVAASGLNTML 269 ++++ D A+NG++H++D+ + + +NN Q I+ ++ + R+ + + L L Sbjct: 485 KIIQGDIIASNGLLHILDRAMDKLEPTFESNNEQTIMTMLQPRYSKFRSLLEETNLGHAL 544 Query: 270 EGNG---QYTLLAPTNEAFEKIPSETLNRILGDPEALR---DLLNNHILKSAMCAEA-IV 322 + +G YT+ P NEA + TL+ +L PE R +L+ HI+ A ++ Sbjct: 545 DEDGVGGPYTIFVPNNEALNNMKDGTLDYLL-SPEGSRKLLELVRYHIVPFTQLEVATLI 603 Query: 323 AGLSVETLEGTTLEVGCSGDMLTINGKAIISNKDILATNGVIHYIDELLIPDS 375 + + ++ ++ + + + + +I A NG I+ + +LIP S Sbjct: 604 STPHIRSMANQLIQFNTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIPPS 656 Score = 50.4 bits (119), Expect = 5e-06 Identities = 33/104 (31%), Positives = 56/104 (53%), Gaps = 9/104 (8%) Query: 535 GVYTVFAPTNEAFRALPPRERSRLLGDAKE--LANILKYHI-GDEILVSGGIGALVRLKS 591 G +TVFAP + AF E +R+ K + +L+YH+ L+ + + S Sbjct: 1628 GPFTVFAPLSAAFD-----EEARVKDWDKYGLMPQVLRYHVVACHQLLLENLKLISNATS 1682 Query: 592 LQGDKLEVSLKNNVVSVN-KEPVAEPDIMATNGVVHVITNVLQP 634 LQG+ + +S+ + V +N K + DI++TNG+VH+I +L P Sbjct: 1683 LQGEPIVISVSQSTVYINNKAKIISSDIISTNGIVHIIDKLLSP 1726 Score = 49.7 bits (117), Expect = 9e-06 Identities = 56/227 (24%), Positives = 97/227 (42%), Gaps = 29/227 (12%) Query: 438 HIIKDQLASKYLYHGQTLETLGGKKLRVFVYRNSLCIENSC--------IAAHDKRGRYG 489 HII Q+ +Y+ + TL GK +F I+ I D G Sbjct: 437 HIIAGQMNIEYMNNTDMFYTLTGKSGEIFNSDKDNQIKLKLHGGKKKVKIIQGDIIASNG 496 Query: 490 TLFTMDRV---LTPPMG-----TVMDVLKGDNRFSMLVAAIQSAGLTETLNREGV---YT 538 L +DR L P T+M +L+ R+S + ++ L L+ +GV YT Sbjct: 497 LLHILDRAMDKLEPTFESNNEQTIMTMLQP--RYSKFRSLLEETNLGHALDEDGVGGPYT 554 Query: 539 VFAPTNEAFRALPPRERSRLLGD--AKELANILKYHIGDEILVSGGIGALV---RLKSLQ 593 +F P NEA + LL +++L +++YHI + + L+ ++S+ Sbjct: 555 IFVPNNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLE--VATLISTPHIRSMA 612 Query: 594 GDKLEVSLKNN-VVSVNKEPVAEPDIMATNGVVHVITNVLQPPANRP 639 ++ + +N + N + E +I A NG ++ +T VL PP+ P Sbjct: 613 NQLIQFNTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIPPSIVP 659 Score = 47.4 bits (111), Expect = 4e-05 Identities = 62/280 (22%), Positives = 117/280 (41%), Gaps = 30/280 (10%) Query: 381 ELAAESDVSTAIDLFRQAGLGNHLSGSERLTLLAPLNSVFKDGTPP------IDAHTRNL 434 EL+ S+ + A L LS + LT+L P +D ++ L Sbjct: 1000 ELSFLSEAAIFNRWINNASLQPTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPAL 1059 Query: 435 LRNHIIKDQLASKYLYHGQTLET-------LGGKKLRVFVYRNSLCIENSCIAAHDKRGR 487 ++ H++ L + + QTL + L G L + ++ IE + I D Sbjct: 1060 IKYHML---LGTYRVADLQTLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAAT 1116 Query: 488 YGTLFTMDRVLTPPM---GTVMDVLKGDNR---FSMLVAAIQSAGLTETLNREGVYTVFA 541 G + +++VL P G++ ++L + +S+ I L + YTVFA Sbjct: 1117 NGVIHIINKVLVPQRRLTGSLPNLLMRLEQMPDYSIFRGYIIQYNLANAIEAADAYTVFA 1176 Query: 542 PTNEAFRALPPRERSRLLGDAKELANILKYHIG-DEILVSGGIGALVRLKSLQGDKLEVS 600 P N A ++ L + ++L+YH+ +E L+ + + +++ G +S Sbjct: 1177 PNNNAIENYIREKKVLSLEE-----DVLRYHVVLEEKLLKNDLHNGMHRETMLGFSYFLS 1231 Query: 601 --LKNNVVSVNKEPVAEPDIMATNGVVHVITNVLQPPANR 638 L N+ + VN+ P+ ++ GV+H + VL+ NR Sbjct: 1232 FFLHNDQLYVNEAPINYTNVATDKGVIHGLGKVLEIQKNR 1271 Score = 45.1 bits (105), Expect = 2e-04 Identities = 61/258 (23%), Positives = 104/258 (40%), Gaps = 34/258 (13%) Query: 273 GQYTLLAPTNEAFEKIPSETLNRILGDPEALRDLLNNHILKSAMCAEAIVAGLSVETLEG 332 G +T+L PT++ + +N +L D +A + + HI+ M E + TL G Sbjct: 403 GPFTVLLPTDKGLKGF---NVNELLVDNKAAQYFVKLHIIAGQMNIEYMNNTDMFYTLTG 459 Query: 333 TTLEVGCSGD----MLTING---KAIISNKDILATNGVIHYIDELLIPDSAKTLFELAAE 385 + E+ S L ++G K I DI+A+NG++H +D + D + FE E Sbjct: 460 KSGEIFNSDKDNQIKLKLHGGKKKVKIIQGDIIASNGLLHILDRAM--DKLEPTFESNNE 517 Query: 386 SDVSTAI--------DLFRQAGLGNHLSG---SERLTLLAPLNSV---FKDGT------P 425 + T + L + LG+ L T+ P N KDGT P Sbjct: 518 QTIMTMLQPRYSKFRSLLEETNLGHALDEDGVGGPYTIFVPNNEALNNMKDGTLDYLLSP 577 Query: 426 PIDAHTRNLLRNHIIK-DQLASKYLYHGQTLETLGGKKLRVFVYRNSLCIENS-CIAAHD 483 L+R HI+ QL L + ++ + ++ N + N + + Sbjct: 578 EGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQLIQFNTTDNGQILANDVAMEEIE 637 Query: 484 KRGRYGTLFTMDRVLTPP 501 + G ++T+ VL PP Sbjct: 638 ITAKNGRIYTLTGVLIPP 655 Score = 43.9 bits (102), Expect = 5e-04 Identities = 77/351 (21%), Positives = 135/351 (38%), Gaps = 58/351 (16%) Query: 272 NGQYTLLAPTNEAFEKIPSETLNRILGDPEALRDLLNNHILKSAMCAEAIVAGLSVETLE 331 N + T P A +P+ T GD + L+N + K+ C+E + + + Sbjct: 1527 NAECTQTGPNQAACNCLPAYT-----GDGKVCT-LINVCLTKNGGCSEFAICNHTGQVER 1580 Query: 332 GTTLEVGCSGDMLTINGKAIISNKDILATNGVIHYIDELLIPDSAKTLFELAAESDVSTA 391 T + GD T G Y + P +++ F+L Sbjct: 1581 TCTCKPNYIGDGFTCRGSI---------------YQELPKNPKTSQYFFQL--------- 1616 Query: 392 IDLFRQAGLGNHLSGSERLTLLAPLNSVFKDGTPPIDAHTRNL----LRNHIIK-DQLAS 446 Q L G T+ APL++ F + D L LR H++ QL Sbjct: 1617 -----QEHFVKDLVGPGPFTVFAPLSAAFDEEARVKDWDKYGLMPQVLRYHVVACHQLLL 1671 Query: 447 KYLYHGQTLETLGGKKLRVFVYRNSLCIENSC-IAAHDKRGRYGTLFTMDRVLTPP---- 501 + L +L G+ + + V ++++ I N I + D G + +D++L+P Sbjct: 1672 ENLKLISNATSLQGEPIVISVSQSTVYINNKAKIISSDIISTNGIVHIIDKLLSPKNLLI 1731 Query: 502 -----MGTVMD---VLKGDNRFSMLVAAIQSAGLTETLNR--EGVYTVFAPTNEAFRALP 551 G ++ L +N + IQ +GL + T+F PT++A ALP Sbjct: 1732 TPKDNSGRILQNLTTLATNNGYIKFSNLIQDSGLLSVITDPIHTPVTLFWPTDQALHALP 1791 Query: 552 PRERSRLLG--DAKELANILKYH-IGDEILVSGGIGALVRLKSLQGDKLEV 599 ++ L + +L LK+H I D +++ + K+LQG +L V Sbjct: 1792 AEQQDFLFNQDNKDKLKEYLKFHVIRDAKVLAVDLPTSTAWKTLQGSELSV 1842 Score = 38.1 bits (87), Expect = 0.027 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 1/102 (0%) Query: 136 GSFTIFAPSNEAWASLPAEVLDSLVS-NVNIELLNALRYHMVGRRVLTDELKHGMTLTSM 194 G +TIF P+NEA ++ LD L+S + +LL +RYH+V L Sbjct: 551 GPYTIFVPNNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRS 610 Query: 195 YQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVI 236 N IQ + NG + N + + + A NG ++ + V+ Sbjct: 611 MANQLIQFNTTDNGQILANDVAMEEIEITAKNGRIYTLTGVL 652 Score = 34.3 bits (77), Expect = 0.39 Identities = 29/113 (25%), Positives = 53/113 (46%), Gaps = 11/113 (9%) Query: 132 MEGPGSFTIFAPSNEAWASLPAEVLDSLVSNVNIELL--NALRYHMV-GRRVLTDELKHG 188 +E ++T+FAP+N A +++ + + L + LRYH+V ++L ++L +G Sbjct: 1166 IEAADAYTVFAPNNNA--------IENYIREKKVLSLEEDVLRYHVVLEEKLLKNDLHNG 1217 Query: 189 MTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVISTITN 241 M +M S N + VN A + + GV+H + KV+ N Sbjct: 1218 MHRETMLGFSYFLSFFLHNDQLYVNEAPINYTNVATDKGVIHGLGKVLEIQKN 1270 Score = 33.9 bits (76), Expect = 0.51 Identities = 34/110 (30%), Positives = 53/110 (48%), Gaps = 10/110 (9%) Query: 294 NRILGDPEAL--RDLLNNHILKSAMCAEAIVAGLSVETLEGTTLEVGCSGDMLT------ 345 N LG+ E L RD+ ++ S +V G +++T G+ L + S D L Sbjct: 2362 NSGLGENETLSGRDIEHHLANVSMFFYNDLVNGTTLQTRLGSKLLITASQDPLQPTETRF 2421 Query: 346 INGKAIISNKDILATNGVIHYIDE-LLIPDSAKTLFELAAESDVSTAIDL 394 ++G+AI+ DI A+NG+IH I L P + TL + + AI L Sbjct: 2422 VDGRAILQ-WDIFASNGIIHVISRPLKAPPAPVTLTHTGLGAGIFFAIIL 2470 Score = 31.6 bits (70), Expect = 2.5 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 20/106 (18%) Query: 538 TVFAPTNEAFRALPPRERSRLLGDAKE--LANILKYHIGDEILVSGGIGALVRLKSLQGD 595 T+F P N E L G E LAN+ + D LV+G L++ G Sbjct: 2356 TLFVPQNSGLG-----ENETLSGRDIEHHLANVSMFFYND--LVNG-----TTLQTRLGS 2403 Query: 596 KLEVSLKNNVVS------VNKEPVAEPDIMATNGVVHVITNVLQPP 635 KL ++ + + V+ + + DI A+NG++HVI+ L+ P Sbjct: 2404 KLLITASQDPLQPTETRFVDGRAILQWDIFASNGIIHVISRPLKAP 2449 >gi|61743978 stabilin 1 precursor [Homo sapiens] Length = 2570 Score = 67.4 bits (163), Expect = 4e-11 Identities = 59/264 (22%), Positives = 114/264 (43%), Gaps = 25/264 (9%) Query: 131 EMEGPGSFTIFAPSNEAWASLPAEVLDSLVSNVNIELLNALRYHMVGRRVLTDELKHGMT 190 E++G G FTIF P + ++L + L + ++ + RYH+VG R L E Sbjct: 1607 ELKGDGPFTIFVPHADLMSNLSQDELARIRAHRQL----VFRYHVVGCRRLRSEDLLEQG 1662 Query: 191 LTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVI------------ST 238 + ++ I + AR++ +DH A NG++H ID+V+ + Sbjct: 1663 YATALSGHPLRFSEREGSIYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDDAP 1722 Query: 239 ITNNIQQIIEIEDTFETLRAAVAASGLNTMLE--GNGQYTLLAPTNEAFEKIPSETLNRI 296 I ++ + +GL +L + +T+L PT+ AF +P + + Sbjct: 1723 IPRRNVTAAAQGFGYKIFSGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQAWL 1782 Query: 297 LGDP--EALRDLLNNHILKSAMCAEAIVAGLS-VETLEGTTLEVGCS----GDMLTINGK 349 + + L +L H++++ + + L + T+ GT + CS G+++ Sbjct: 1783 YHEDHRDKLAAILRGHMIRNVEALASDLPNLGPLRTMHGTPISFSCSRTRAGELMVGEDD 1842 Query: 350 AIISNKDILATNGVIHYIDELLIP 373 A I + + G+ + ID+LL P Sbjct: 1843 ARIVQRHLPFEGGLAYGIDQLLEP 1866 Score = 60.1 bits (144), Expect = 7e-09 Identities = 42/149 (28%), Positives = 70/149 (46%), Gaps = 15/149 (10%) Query: 501 PMGTVMDVLKGDNRFSMLVAAIQSAGLTETLNREGVYTVFAPTNEAFRALPPRERSRLL- 559 P T+ +L FS +++ GL L+ G +TVFAP+NEA +L L Sbjct: 505 PKRTIGQILASTEAFSRFETILENCGLPSILDGPGPFTVFAPSNEAVDSLRDGRLIYLFT 564 Query: 560 GDAKELANILKYHIGD------EILVSGGIGALVRLKSLQGDKLEVSLKNN---VVSVNK 610 +L +++YHI + E L+S G R+ ++ L V++ ++ Sbjct: 565 AGLSKLQELVRYHIYNHGQLTVEKLISKG-----RILTMANQVLAVNISEEGRILLGPEG 619 Query: 611 EPVAEPDIMATNGVVHVITNVLQPPANRP 639 P+ D+MA NGV+H++ +L PP P Sbjct: 620 VPLQRVDVMAANGVIHMLDGILLPPTILP 648 Score = 58.5 bits (140), Expect = 2e-08 Identities = 61/261 (23%), Positives = 109/261 (41%), Gaps = 35/261 (13%) Query: 136 GSFTIFAPSNEAWASLPAEVLDSLVSNVNIELLNAL-RYHMV-GRRVLTDELKH------ 187 G FT+ PS +++S +N L L R H++ G+ +L D Sbjct: 395 GPFTVLVPSVSSFSS----------RTMNASLAQQLCRQHIIAGQHILEDTRTQQTRRWW 444 Query: 188 ---GMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVISTITNN-- 242 G +T + + Y + + KA++ A NGV H++ + + Sbjct: 445 TLAGQEITVTFNQFTKYSYKYKDQ--PQQTFNIYKANNIAANGVFHVVTGLRWQAPSGTP 502 Query: 243 ------IQQIIEIEDTFETLRAAVAASGLNTMLEGNGQYTLLAPTNEAFEKIPSETLNRI 296 I QI+ + F + GL ++L+G G +T+ AP+NEA + + L + Sbjct: 503 GDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGPFTVFAPSNEAVDSLRDGRLIYL 562 Query: 297 L-GDPEALRDLLNNHILK-SAMCAEAIVAGLSVETLEGTTLEVGCS--GDMLTINGKAII 352 L++L+ HI + E +++ + T+ L V S G +L + Sbjct: 563 FTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMANQVLAVNISEEGRILLGPEGVPL 622 Query: 353 SNKDILATNGVIHYIDELLIP 373 D++A NGVIH +D +L+P Sbjct: 623 QRVDVMAANGVIHMLDGILLP 643 Score = 52.8 bits (125), Expect = 1e-06 Identities = 36/107 (33%), Positives = 53/107 (49%), Gaps = 2/107 (1%) Query: 132 MEGPGSFTIFAPSNEAWASLPAEVLDSLVSNVNIELLNALRYHMVGRRVLTDE--LKHGM 189 ++GPG FT+FAPSNEA SL L L + +L +RYH+ LT E + G Sbjct: 535 LDGPGPFTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGR 594 Query: 190 TLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVI 236 LT Q + I ++ L + D A NGV+H++D ++ Sbjct: 595 ILTMANQVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGIL 641 Score = 51.2 bits (121), Expect = 3e-06 Identities = 56/219 (25%), Positives = 97/219 (44%), Gaps = 25/219 (11%) Query: 269 LEGNGQYTLLAPTNEAFEKIPSETLNRILGDPEALRDLLNNHILKSAMCAEAI--VAGLS 326 L + + T L P+ A ++ E L P L +L+ H L+ A+ E + + G Sbjct: 1015 LPADRRVTALVPSEAAVRQLSPEDRAFWL-QPRTLPNLVRAHFLQGALFEEELARLGGQE 1073 Query: 327 VETLEGTTLEVGCSGDMLTINGKAIISNK-----DILATNGVIHYIDELLIPDSAKTL-- 379 V TL TT ++ I+G+ + N D+LATNGV+H + ++L+P Sbjct: 1074 VATLNPTT-----RWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGG 1128 Query: 380 FELAAESDVSTAIDLFRQA----GLGNHLSGSERLTLLAPLNSVF--KDGTPPIDAHTRN 433 L + D+ A LFR+ GL + + T+ P N + + +DA T Sbjct: 1129 QGLLQQLDLVPAFSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADT-- 1186 Query: 434 LLRNHII-KDQLASKYLYHGQTLETLGGKKLRVFVYRNS 471 +R+H++ + L+ + L G +L G + Y +S Sbjct: 1187 -VRHHVVLGEALSMETLRKGGHRNSLLGPAHWIVFYNHS 1224 Score = 48.1 bits (113), Expect = 3e-05 Identities = 39/138 (28%), Positives = 66/138 (47%), Gaps = 10/138 (7%) Query: 503 GTVMDVLKGDNRFSMLVAAIQSAGLTETLNREGVYTVFAPTNEAFRALPPRERSRLLGDA 562 G + L+ + FS+ ++SAG+T +R T P+ A R L P +R+ L Sbjct: 989 GDIFRELEANAHFSIFYQWLKSAGITLPADRR--VTALVPSEAAVRQLSPEDRAFWL-QP 1045 Query: 563 KELANILKYH-----IGDEILVSGGIGALVRLKSLQGDKLEVSLKNNVVSVNKEPVAEPD 617 + L N+++ H + +E L G + L + E+ + V V V D Sbjct: 1046 RTLPNLVRAHFLQGALFEEELARLGGQEVATLNPTT--RWEIRNISGRVWVQNASVDVAD 1103 Query: 618 IMATNGVVHVITNVLQPP 635 ++ATNGV+H+++ VL PP Sbjct: 1104 LLATNGVLHILSQVLLPP 1121 Score = 47.0 bits (110), Expect = 6e-05 Identities = 60/261 (22%), Positives = 108/261 (41%), Gaps = 30/261 (11%) Query: 404 LSGSERLTLLAP----LNSVFKDGTPPIDAHTRNLLRNHIIK-DQLASKYLYHGQTLETL 458 L G T+ P ++++ +D I AH + + R H++ +L S+ L L Sbjct: 1608 LKGDGPFTIFVPHADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLEQGYATAL 1667 Query: 459 GGKKLRVFVYRNSLCIENSC-IAAHDKRGRYGTLFTMDRVLTPPMG-------------T 504 G LR S+ + + + + D G L +DRVL PP Sbjct: 1668 SGHPLRFSEREGSIYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDDAPIPRRN 1727 Query: 505 VMDVLKGDNRFSMLVAAIQSAGLTETLNREG--VYTVFAPTNEAFRALPPRERSRLLGD- 561 V +G + + ++ AGL L +T+ PT+ AFRALPP ++ L + Sbjct: 1728 VTAAAQGFG-YKIFSGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQAWLYHED 1786 Query: 562 -AKELANILKYH-IGDEILVSGGIGALVRLKSLQGDKLEVSLKNN-----VVSVNKEPVA 614 +LA IL+ H I + ++ + L L+++ G + S +V + + Sbjct: 1787 HRDKLAAILRGHMIRNVEALASDLPNLGPLRTMHGTPISFSCSRTRAGELMVGEDDARIV 1846 Query: 615 EPDIMATNGVVHVITNVLQPP 635 + + G+ + I +L+PP Sbjct: 1847 QRHLPFEGGLAYGIDQLLEPP 1867 Score = 46.6 bits (109), Expect = 8e-05 Identities = 46/184 (25%), Positives = 73/184 (39%), Gaps = 17/184 (9%) Query: 381 ELAAESDVSTAIDLFRQAGLGNHLSGSERLTLLAPLNSVFKDGTPPIDAH------TRNL 434 EL A + S + AG+ L R+T L P + + +P A NL Sbjct: 994 ELEANAHFSIFYQWLKSAGIT--LPADRRVTALVPSEAAVRQLSPEDRAFWLQPRTLPNL 1051 Query: 435 LRNHIIKDQLASKYLYH--GQTLETLGGK-KLRVFVYRNSLCIENSCIAAHDKRGRYGTL 491 +R H ++ L + L GQ + TL + + + ++N+ + D G L Sbjct: 1052 VRAHFLQGALFEEELARLGGQEVATLNPTTRWEIRNISGRVWVQNASVDVADLLATNGVL 1111 Query: 492 FTMDRVLTPPMGTV------MDVLKGDNRFSMLVAAIQSAGLTETLNREGVYTVFAPTNE 545 + +VL PP G V + L FS+ +Q GL + YT+F PTN Sbjct: 1112 HILSQVLLPPRGDVPGGQGLLQQLDLVPAFSLFRELLQHHGLVPQIEAATAYTIFVPTNR 1171 Query: 546 AFRA 549 + A Sbjct: 1172 SLEA 1175 Score = 42.4 bits (98), Expect = 0.001 Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 9/128 (7%) Query: 167 LLNALRYHMVGRRVLTDELKH--GMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHA 224 L N +R H + + +EL G + ++ + +I + +G V V A + AD A Sbjct: 1048 LPNLVRAHFLQGALFEEELARLGGQEVATLNPTTRWEIRNI-SGRVWVQNASVDVADLLA 1106 Query: 225 TNGVVHLIDKVISTITNNIQ------QIIEIEDTFETLRAAVAASGLNTMLEGNGQYTLL 278 TNGV+H++ +V+ ++ Q +++ F R + GL +E YT+ Sbjct: 1107 TNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPAFSLFRELLQHHGLVPQIEAATAYTIF 1166 Query: 279 APTNEAFE 286 PTN + E Sbjct: 1167 VPTNRSLE 1174 Score = 37.4 bits (85), Expect = 0.046 Identities = 27/110 (24%), Positives = 50/110 (45%), Gaps = 6/110 (5%) Query: 269 LEGNGQYTLLAPTNEAFEKIPSETLNRILGDPEALRDLLNNHILKSA--MCAEAIVAGLS 326 L+G+G +T+ P + + + L RI A R L+ + + + +E ++ Sbjct: 1608 LKGDGPFTIFVPHADLMSNLSQDELARI----RAHRQLVFRYHVVGCRRLRSEDLLEQGY 1663 Query: 327 VETLEGTTLEVGCSGDMLTINGKAIISNKDILATNGVIHYIDELLIPDSA 376 L G L + +N A + + D A NG++H+ID +L+P A Sbjct: 1664 ATALSGHPLRFSEREGSIYLNDFARVVSSDHEAVNGILHFIDRVLLPPEA 1713 >gi|39725938 polymerase (RNA) III (DNA directed) polypeptide A, 155kDa [Homo sapiens] Length = 1390 Score = 34.3 bits (77), Expect = 0.39 Identities = 40/174 (22%), Positives = 70/174 (40%), Gaps = 23/174 (13%) Query: 203 HHYPNGIVTVNCARLLKADHHATNGVVHLIDKVISTITNNIQQIIEIEDTFETLRAAVAA 262 HH TV LLK H ++D ++S + + IE E L A Sbjct: 157 HHCGAFNGTVKKCGLLKIIHEKYKTNKKVVDPIVSNFLQSFETAIEHNKEVEPLLGR-AQ 215 Query: 263 SGLNTMLEGNGQYTLLAPTNEAFEKIPSETLNRILGDPEALR--DLLNNHILKSAMCAEA 320 LN ++ N F++IP+E + +L +PEA + DL+ +L +C Sbjct: 216 ENLNPLVVLN-----------LFKRIPAEDVPLLLMNPEAGKPSDLILTRLLVPPLCIRP 264 Query: 321 IVAGLSVETLEGTTLEVGCSGDMLTINGKAIISNKDILATNGVIHYIDELLIPD 374 V + L+ G + D LT+ II D++ + + ++++ D Sbjct: 265 SVV---------SDLKSGTNEDDLTMKLTEIIFLNDVIKKHRISGAKTQMIMED 309 >gi|118572599 formin homology 2 domain containing 1 [Homo sapiens] Length = 1164 Score = 31.2 bits (69), Expect = 3.3 Identities = 16/41 (39%), Positives = 24/41 (58%) Query: 543 TNEAFRALPPRERSRLLGDAKELANILKYHIGDEILVSGGI 583 T + RAL RER R G+ K L LK +GD+++ + G+ Sbjct: 1116 TKSSPRALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGL 1156 >gi|227499621 solute carrier family 27 (fatty acid transporter), member 2 isoform 2 [Homo sapiens] Length = 567 Score = 30.4 bits (67), Expect = 5.7 Identities = 30/130 (23%), Positives = 51/130 (39%), Gaps = 13/130 (10%) Query: 177 GRRVLTDELKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNG---VVHLID 233 G V T E+ + L Q N+ H P+ + A + ++H +G H+ D Sbjct: 436 GENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGKKLFQHIAD 495 Query: 234 KVISTITN---NIQQIIEIEDTFETLRAAVAASGLNTMLEGNGQYTL-------LAPTNE 283 + S IQ IEI TF+ + + G N + + Y L + T + Sbjct: 496 YLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAKMYVPMTED 555 Query: 284 AFEKIPSETL 293 + I ++TL Sbjct: 556 IYNAISAKTL 565 >gi|227499619 solute carrier family 27 (fatty acid transporter), member 2 isoform 1 [Homo sapiens] Length = 620 Score = 30.4 bits (67), Expect = 5.7 Identities = 30/130 (23%), Positives = 51/130 (39%), Gaps = 13/130 (10%) Query: 177 GRRVLTDELKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNG---VVHLID 233 G V T E+ + L Q N+ H P+ + A + ++H +G H+ D Sbjct: 489 GENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGKKLFQHIAD 548 Query: 234 KVISTITN---NIQQIIEIEDTFETLRAAVAASGLNTMLEGNGQYTL-------LAPTNE 283 + S IQ IEI TF+ + + G N + + Y L + T + Sbjct: 549 YLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAKMYVPMTED 608 Query: 284 AFEKIPSETL 293 + I ++TL Sbjct: 609 IYNAISAKTL 618 >gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapiens] Length = 1029 Score = 30.4 bits (67), Expect = 5.7 Identities = 23/81 (28%), Positives = 42/81 (51%), Gaps = 7/81 (8%) Query: 545 EAFRALPPRERSRLLGDAKELANILKYHIGDEILVSGG--IGALVRLKSLQGDKLEVSLK 602 E+F+ + P++ + G K N+ + +GD + + GG + A +RL S QG K++ Sbjct: 167 ESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLISAQGCKVD---- 222 Query: 603 NNVVSVNKEPVA-EPDIMATN 622 N+ ++ EP + PD N Sbjct: 223 NSSLTGESEPQSRSPDFTHEN 243 >gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapiens] Length = 820 Score = 30.4 bits (67), Expect = 5.7 Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 21/117 (17%) Query: 277 LLAPTNEAFEKIPSETLNRILGDPEALRDLLNNHILKSAMCAEAIVAGLSVETLEGTTLE 336 +LAPT E ++I ET+ G P +R + A++ G+S E +G L Sbjct: 473 ILAPTRELAQQIEEETIK--FGKPLGIRTV-------------AVIGGISRED-QGFRLR 516 Query: 337 VGCSGDMLTINGKAIISNKDILATNGVIHYIDELLIPDSAKTLFELAAESDVSTAID 393 +GC ++ G+ I D+L ++ ++ D A + ++ E DV ++ Sbjct: 517 MGCE-IVIATPGRLI----DVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILE 568 >gi|154426300 hypothetical protein LOC54934 [Homo sapiens] Length = 492 Score = 30.4 bits (67), Expect = 5.7 Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 11/92 (11%) Query: 73 ICGKSTVISYECCPGYEKVPGEKGCPAAL---PLSNLYETLGVVGSTTTQLY-TDRTEKL 128 IC + + ++CC G E+VP K P +L P L+ L Q+Y ++ + Sbjct: 326 ICQDTNQVLFKCCQGSEEVPCNKPVPVSLSEDPCCPLHFQL------PPQMYKPEQVLSV 379 Query: 129 RPEME-GPGSFTIFAPSNEAWASLPAEVLDSL 159 ++E GP + A + SLP E D L Sbjct: 380 PDDLEAGPMDLYLSAAELQPTESLPLEFSDDL 411 >gi|223941923 OTU domain containing 1 [Homo sapiens] Length = 481 Score = 29.6 bits (65), Expect = 9.6 Identities = 18/52 (34%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Query: 117 TTQLYTDRTEKLRPEMEGP-GSFTIFAPSNEAWASLPAEVLDSLVSNVNIEL 167 T D + P +EG G F I A + AWA P + + NVNI L Sbjct: 343 TVHYIADHLDHFSPLIEGDVGEFIIAAAQDGAWAGYPELLAMGQMLNVNIHL 394 >gi|88900507 protein arginine methyltransferase 5 isoform b [Homo sapiens] Length = 620 Score = 29.6 bits (65), Expect = 9.6 Identities = 16/51 (31%), Positives = 21/51 (41%) Query: 91 VPGEKGCPAALPLSNLYETLGVVGSTTTQLYTDRTEKLRPEMEGPGSFTIF 141 + + C P+ G G T LY D T +RPE PG F+ F Sbjct: 513 IDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWF 563 >gi|20070220 protein arginine methyltransferase 5 isoform a [Homo sapiens] Length = 637 Score = 29.6 bits (65), Expect = 9.6 Identities = 16/51 (31%), Positives = 21/51 (41%) Query: 91 VPGEKGCPAALPLSNLYETLGVVGSTTTQLYTDRTEKLRPEMEGPGSFTIF 141 + + C P+ G G T LY D T +RPE PG F+ F Sbjct: 530 IDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWF 580 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.134 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,345,917 Number of Sequences: 37866 Number of extensions: 1058579 Number of successful extensions: 2803 Number of sequences better than 10.0: 17 Number of HSP's better than 10.0 without gapping: 10 Number of HSP's successfully gapped in prelim test: 7 Number of HSP's that attempted gapping in prelim test: 2630 Number of HSP's gapped (non-prelim): 53 length of query: 683 length of database: 18,247,518 effective HSP length: 109 effective length of query: 574 effective length of database: 14,120,124 effective search space: 8104951176 effective search space used: 8104951176 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.