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Search of human proteins with 4507447
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507447 transcription factor AP-4 (activating enhancer
binding protein 4) [Homo sapiens]
(338 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507447 transcription factor AP-4 (activating enhancer bindin... 664 0.0
gi|9945318 MAX binding protein [Homo sapiens] 55 7e-08
gi|221139761 zinc finger protein 853 [Homo sapiens] 53 3e-07
gi|14602433 Williams Beuren syndrome chromosome region 14 isofor... 52 8e-07
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 51 1e-06
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 50 2e-06
gi|32967514 neurofibromin 2 isoform 7 [Homo sapiens] 50 2e-06
gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens] 50 2e-06
gi|32967266 neurofibromin 2 isoform 2 [Homo sapiens] 50 2e-06
gi|32967264 neurofibromin 2 isoform 7 [Homo sapiens] 50 2e-06
gi|32967262 neurofibromin 2 isoform 6 [Homo sapiens] 50 2e-06
gi|32967260 neurofibromin 2 isoform 5 [Homo sapiens] 50 2e-06
gi|32451486 neurofibromin 2 isoform 2 [Homo sapiens] 50 2e-06
gi|14602437 Williams Beuren syndrome chromosome region 14 isofor... 50 3e-06
gi|4557795 neurofibromin 2 isoform 1 [Homo sapiens] 50 3e-06
gi|148746195 trichohyalin [Homo sapiens] 50 4e-06
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 49 5e-06
gi|17981708 twist homolog 2 [Homo sapiens] 49 8e-06
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 49 8e-06
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 49 8e-06
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 49 8e-06
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 49 8e-06
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 49 8e-06
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 49 8e-06
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 49 8e-06
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 49 8e-06
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 47 2e-05
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 47 2e-05
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 47 2e-05
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 47 2e-05
>gi|4507447 transcription factor AP-4 (activating enhancer binding
protein 4) [Homo sapiens]
Length = 338
Score = 664 bits (1714), Expect = 0.0
Identities = 338/338 (100%), Positives = 338/338 (100%)
Query: 1 MEYFMVPTQKVPSLQHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRR 60
MEYFMVPTQKVPSLQHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRR
Sbjct: 1 MEYFMVPTQKVPSLQHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRR 60
Query: 61 MQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQEL 120
MQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQEL
Sbjct: 61 MQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQEL 120
Query: 121 SGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRSLE 180
SGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRSLE
Sbjct: 121 SGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRSLE 180
Query: 181 AHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRTQLLPPPAPTHHPTVIVPAP 240
AHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRTQLLPPPAPTHHPTVIVPAP
Sbjct: 181 AHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRTQLLPPPAPTHHPTVIVPAP 240
Query: 241 PPPPSHHINVVTMGPSSVINSVSTSRQNLDTIVQAIQHIEGTQEKQELEEEQRRAVIVKP 300
PPPPSHHINVVTMGPSSVINSVSTSRQNLDTIVQAIQHIEGTQEKQELEEEQRRAVIVKP
Sbjct: 241 PPPPSHHINVVTMGPSSVINSVSTSRQNLDTIVQAIQHIEGTQEKQELEEEQRRAVIVKP 300
Query: 301 VRSCPEAPTSDTASDSEASDSDAMDQSREEPSGDGELP 338
VRSCPEAPTSDTASDSEASDSDAMDQSREEPSGDGELP
Sbjct: 301 VRSCPEAPTSDTASDSEASDSDAMDQSREEPSGDGELP 338
>gi|9945318 MAX binding protein [Homo sapiens]
Length = 582
Score = 55.5 bits (132), Expect = 7e-08
Identities = 66/284 (23%), Positives = 105/284 (36%), Gaps = 54/284 (19%)
Query: 30 SLANIPLTP-ETQRDQERRIR------REIANSNERRRMQSINAGFQSLKTLIPHTDGEK 82
+L + L P E + E++ R RE+ N E+ R + F++LK IP+ D +K
Sbjct: 195 TLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLKRNIPNVDDKK 254
Query: 83 LSKAAILQQTAEYIFSL-------EQEKTRLLQQNTQLKRFIQELSGSSP---------- 125
S ++L+ YI SL E E RL ++ ++ + EL
Sbjct: 255 TSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHELSQWMDVLEIDR 314
Query: 126 ---KRRRAEDKDEGIGSPDIWEDEKAEDLRREMIEL-------RQQLDKERSVRMMLEEQ 175
+ + ED + ED ED+ + L R Q + +S
Sbjct: 315 VLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTT 374
Query: 176 VRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRTQLLPPPAPTHHPTV 235
L H +P V L QQ+Q QQ PPP P
Sbjct: 375 PAPLPPHPHPHPHSVALPPAHLPVQQQQ------------PQQKTPLPAPPPPPAAPAQT 422
Query: 236 IVPAPPPPPSHHINVVTMGPSSVINSVSTSRQNLDTIVQAIQHI 279
+VPAP H+ G S+VI +T+ +++Q + H+
Sbjct: 423 LVPAPA-----HLVATAGGGSTVIAHTATTHA---SVIQTVNHV 458
Score = 33.1 bits (74), Expect = 0.36
Identities = 28/99 (28%), Positives = 46/99 (46%), Gaps = 17/99 (17%)
Query: 162 LDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQV-RLLHQEKLEREQQQLR 220
L+ R + ++Q R+ E E+L++ ++ Q Q++ + RL H +E + +
Sbjct: 7 LEAARFLEWQAQQQQRAREEQ---ERLRLEQEREQEQKKANSLARLAHTLPVEEPRMEAP 63
Query: 221 TQLLPPPAPTHHPTVIVPAPPPPPSHHINVVTMGPSSVI 259
L PPAP PAPPPP + T P +VI
Sbjct: 64 PLPLSPPAPP-------PAPPPP------LATPAPLTVI 89
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 53.1 bits (126), Expect = 3e-07
Identities = 33/144 (22%), Positives = 78/144 (54%), Gaps = 8/144 (5%)
Query: 89 LQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKD-----EGIGSPDIW 143
LQQ E + + + ++ ++LQQ QL++ +QE ++ + + + E +
Sbjct: 170 LQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQ 229
Query: 144 EDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQ 203
+ ++ +++++ L+QQ ++ +L++Q L+ + ++ + QQ+ LQQQ++
Sbjct: 230 QQQEQLQQQQQLLLLQQQGQLQQQ---LLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQL 286
Query: 204 VRLLHQEKLEREQQQLRTQLLPPP 227
+ Q+ L+++Q+QL+ Q L PP
Sbjct: 287 QQQQQQQLLQQQQEQLQQQQLQPP 310
Score = 43.1 bits (100), Expect = 4e-04
Identities = 45/202 (22%), Positives = 91/202 (45%), Gaps = 17/202 (8%)
Query: 41 QRDQERRIRREIANSNERRRMQSINAGFQSLKT----LIPHTDGEKLSKAAILQQTAEYI 96
Q+ QE+ ++++ E+ + Q + L+ L+ G+ + QQ
Sbjct: 205 QQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQ 264
Query: 97 FSLEQEKTRLLQQNT-QLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREM 155
LEQ++ +L QQ Q + +Q+ +++ E + P E E+ E++ E+
Sbjct: 265 QLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELEL 324
Query: 156 IEL----RQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQE- 210
+ + Q+L+++R +E R E KL+ QQ++ Q +Q+Q +L QE
Sbjct: 325 MPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEV 384
Query: 211 -------KLEREQQQLRTQLLP 225
+L +QQ+++ +L P
Sbjct: 385 QLELTPVELGAQQQEVQLELTP 406
Score = 41.2 bits (95), Expect = 0.001
Identities = 42/188 (22%), Positives = 94/188 (50%), Gaps = 22/188 (11%)
Query: 39 ETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFS 98
E+Q ++E + R NS+ +R S G + G++ + L+Q E
Sbjct: 50 ESQEEEEPQER----NSSPQRPAVSAPVGASEIAE--ETRPGQRELQLQQLEQQPEPQQQ 103
Query: 99 LEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIG----SPDIWEDEKAEDLRRE 154
+ E+ + Q + +L++ Q+ G + ++K + + P++ + + L+ +
Sbjct: 104 PQHEQLQQPQPHLELQQQPQQ-DGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQ 162
Query: 155 MIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLER 214
++ +Q+L ++ +EQ+++ +A ++ +V+ QQ QLQQQ ++ +LL Q++ +
Sbjct: 163 QVQEQQRLQQQ-------QEQLQTQQA----QEQQVLQQQEQLQQQVQEQQLLQQQQEQL 211
Query: 215 EQQQLRTQ 222
+QQQL Q
Sbjct: 212 QQQQLLQQ 219
Score = 36.6 bits (83), Expect = 0.033
Identities = 21/77 (27%), Positives = 45/77 (58%), Gaps = 3/77 (3%)
Query: 146 EKAEDLRREMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVR 205
++ + L+++ +L+ Q +E+ V E+ + ++ ++ + QQ QL QQQEQ
Sbjct: 165 QEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQ-- 222
Query: 206 LLHQEKLEREQQQLRTQ 222
L Q++ +++Q+QL+ Q
Sbjct: 223 -LQQQQFQQQQEQLQQQ 238
Score = 35.0 bits (79), Expect = 0.096
Identities = 30/128 (23%), Positives = 64/128 (50%), Gaps = 8/128 (6%)
Query: 102 EKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQ 161
E+TR Q+ QL++ Q+ P+++ ++ + + + +D ++++ +L+Q+
Sbjct: 80 EETRPGQRELQLQQLEQQ---PEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQE 136
Query: 162 LDK-----ERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQ 216
+ E + L Q + L+ E+ ++ QQ QLQ QQ Q + + Q++ + +Q
Sbjct: 137 KHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQ 196
Query: 217 QQLRTQLL 224
Q QLL
Sbjct: 197 QVQEQQLL 204
Score = 35.0 bits (79), Expect = 0.096
Identities = 30/144 (20%), Positives = 69/144 (47%), Gaps = 9/144 (6%)
Query: 90 QQTAEYIFSLEQEKTRL-----LQQNTQLKRFIQELSGSS-PKRRRAEDKDEGIGSPDIW 143
Q + + L+QEK + L+ QL Q+L +++R + + E + +
Sbjct: 124 QDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQ 183
Query: 144 EDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQ--- 200
E + + + ++++Q ++ + ++Q+ + + ++ + +Q+Q QQQ
Sbjct: 184 EQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLL 243
Query: 201 QEQVRLLHQEKLEREQQQLRTQLL 224
+Q L Q+ L+++Q QL+ QLL
Sbjct: 244 LQQQGQLQQQLLQQQQAQLQQQLL 267
>gi|14602433 Williams Beuren syndrome chromosome region 14 isoform
alpha [Homo sapiens]
Length = 852
Score = 52.0 bits (123), Expect = 8e-07
Identities = 32/89 (35%), Positives = 52/89 (58%), Gaps = 6/89 (6%)
Query: 38 PETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGE---KLSKAAILQQTAE 94
P++ + + RRI A E++R +I GF +L L+ + K+SKA LQ+TAE
Sbjct: 642 PDSNKTENRRITHISA---EQKRRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAE 698
Query: 95 YIFSLEQEKTRLLQQNTQLKRFIQELSGS 123
YI L+QE+ L ++ QL+ I+EL+ +
Sbjct: 699 YILMLQQERAGLQEEAQQLRDEIEELNAA 727
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 51.2 bits (121), Expect = 1e-06
Identities = 56/235 (23%), Positives = 101/235 (42%), Gaps = 33/235 (14%)
Query: 30 SLANIPLTPETQRD-----QERRIRREIANSNERRRMQSINAGFQSLKTLIPHT----DG 80
S+ N+P +RD QE + R E + + Q + + + L+ +
Sbjct: 342 SIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQ 401
Query: 81 EKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSG---SSPKRRRAEDKDEGI 137
+K + + +Q + Q++ ++ + KR ++EL +RRRAE++ +
Sbjct: 402 QKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRV 461
Query: 138 GSPDIWEDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQL 197
+ + E+ +R + L+QQL +E++ M+LE + R +E H E+L Q
Sbjct: 462 EREQEYIRRQLEEEQRHLEVLQQQLLQEQA--MLLECRWREMEEHRQAERL-------QR 512
Query: 198 QQQQEQVRLLHQEKLEREQQQLRTQLLPPP-----APTHHPTVIVPAPPPPPSHH 247
Q QQEQ LL + R +Q PPP P+ H P P +H+
Sbjct: 513 QLQQEQAYLLSLQHDHRRPHPQHSQQPPPPQQERSKPSFH-------APEPKAHY 560
Score = 36.6 bits (83), Expect = 0.033
Identities = 37/114 (32%), Positives = 64/114 (56%), Gaps = 18/114 (15%)
Query: 119 ELSGSSPKRRRAEDKDEGIGSPDIWEDEKAED-LRREMIELRQQLDKERS-----VRMML 172
E SGS + +++ G P + E LRR+ + L+Q+ +KERS +++
Sbjct: 322 EYSGSEEEEEEVPEQE---GEPSSIVNVPGESTLRRDFLRLQQE-NKERSEALRRQQLLQ 377
Query: 173 EEQVRSLEAHMYPEKLKVIAQ-QVQLQQQQEQVRLL-HQEKLERE--QQQLRTQ 222
E+Q+R E + K +++A+ Q +++QQ+EQ R L Q++ ERE +QQ R Q
Sbjct: 378 EQQLREQEEY----KRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQ 427
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 50.4 bits (119), Expect = 2e-06
Identities = 48/192 (25%), Positives = 89/192 (46%), Gaps = 21/192 (10%)
Query: 30 SLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAIL 89
++ N L + QE+ E S + ++ + + K L+P L +
Sbjct: 217 TITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWR 276
Query: 90 QQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAE 149
Q+ L +++ ++ +Q ++ R + L K R E+K +W EK
Sbjct: 277 QEE-----ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEK--------MWRQEKR- 322
Query: 150 DLRREMIELRQQ---LDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRL 206
LR + ELR+Q L +++ +R EEQ++ E M+ ++ K+ Q+ ++ +Q+E RL
Sbjct: 323 -LREQEKELREQEKELREQKELREQ-EEQMQEQEEKMWEQEEKMREQEEKMWRQEE--RL 378
Query: 207 LHQEKLEREQQQ 218
QEK REQ+Q
Sbjct: 379 WEQEKQMREQEQ 390
Score = 45.4 bits (106), Expect = 7e-05
Identities = 38/189 (20%), Positives = 81/189 (42%), Gaps = 2/189 (1%)
Query: 39 ETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFS 98
E R++ER RE E M+ Q + + + + + +Q+ E ++
Sbjct: 583 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWE 642
Query: 99 LEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIEL 158
E++ ++ + +R ++ + E + IWE EK E +E +
Sbjct: 643 QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKK 702
Query: 159 RQQLDKERSVRMM--LEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQ 216
+K R M E+++R E M ++ K+ Q+ ++Q+Q+E++ ++ E+E+
Sbjct: 703 TWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEE 762
Query: 217 QQLRTQLLP 225
+ Q LP
Sbjct: 763 KMWEQQRLP 771
Score = 42.7 bits (99), Expect = 5e-04
Identities = 40/187 (21%), Positives = 92/187 (49%), Gaps = 20/187 (10%)
Query: 42 RDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQ 101
R+QE+ +R + E++ ++ Q + EK+ + ++ E + +
Sbjct: 324 REQEKELREQEKELREQKELREQEEQMQEQE--------EKMWEQE--EKMREQEEKMWR 373
Query: 102 EKTRLLQQNTQLKRFIQELSGSSPKR----RRAEDKDEGIGSPD-IWEDEKAEDLRREM- 155
++ RL +Q Q++ Q++ + R +K+E + + +WE + E +R E
Sbjct: 374 QEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE--QVEKMREEKK 431
Query: 156 IELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLERE 215
++ +++ +++ +M EE++R E M E+ + Q+ ++Q+Q+E + QE+ E +
Sbjct: 432 MQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE--NMWEQEEKEWQ 489
Query: 216 QQQLRTQ 222
QQ+L Q
Sbjct: 490 QQRLPEQ 496
Score = 40.8 bits (94), Expect = 0.002
Identities = 38/198 (19%), Positives = 92/198 (46%), Gaps = 11/198 (5%)
Query: 39 ETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTA----- 93
ET R+QE +++++ N E+ + K + + + + I +Q
Sbjct: 464 ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 523
Query: 94 EYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRR 153
E ++ E++ R + Q + ++ + ++ D++E + +++K D
Sbjct: 524 EEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEE 583
Query: 154 EMIELRQQLDKERSVR----MMLE--EQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLL 207
+M E + ++E+ +R MM E E+++ E M ++ K+ Q+ ++Q+Q+E++
Sbjct: 584 KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQ 643
Query: 208 HQEKLEREQQQLRTQLLP 225
++ E+E++ Q LP
Sbjct: 644 EEKMWEQEEKMWEQQRLP 661
Score = 37.7 bits (86), Expect = 0.015
Identities = 37/176 (21%), Positives = 85/176 (48%), Gaps = 12/176 (6%)
Query: 39 ETQRDQERRIRREIANSNERR-RMQSINAGFQSLKTLIPHTDG------EKLSKAAILQQ 91
E+ R++E+++R E E+ +MQ Q + + + EK+ + L +
Sbjct: 713 ESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPE 772
Query: 92 TAEYIFSLE--QEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAE 149
E ++ E QE+ ++ +Q +++ +++ G K R E+K G +W E E
Sbjct: 773 QKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRG-QEEKMWGQE--E 829
Query: 150 DLRREMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVR 205
+ + ++ Q +K +EE+++ E M ++ K+ Q+ ++++Q+E++R
Sbjct: 830 KMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMR 885
Score = 37.4 bits (85), Expect = 0.019
Identities = 31/150 (20%), Positives = 75/150 (50%), Gaps = 8/150 (5%)
Query: 81 EKLSKAAILQQTAEYIFSLE--QEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIG 138
EK+ + +Q+ E I+ E ++KT+ ++ T + ++E + ++ +++E +
Sbjct: 671 EKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMR 730
Query: 139 SPDIWEDEKAEDLRREMIELRQQLDK--ERSVRMM----LEEQVRSLEAHMYPEKLKVIA 192
+ E+ E ++ + E+ +Q +K E+ +M L EQ L H ++ + I
Sbjct: 731 EQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIW 790
Query: 193 QQVQLQQQQEQVRLLHQEKLEREQQQLRTQ 222
+Q + + QE+ +EK+ +++++R Q
Sbjct: 791 EQEEKMRDQEEKMRGQEEKMRGQEEKMRGQ 820
Score = 35.0 bits (79), Expect = 0.096
Identities = 24/124 (19%), Positives = 67/124 (54%), Gaps = 6/124 (4%)
Query: 99 LEQEKTRLLQQNTQLKRF--IQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMI 156
L +++ R+ +Q ++ ++E + ++ D++E + + E+ + +R E
Sbjct: 406 LREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIR-EREKKMREEEE 464
Query: 157 ELRQQLDK-ERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLERE 215
+R+Q +K ++ M E++ + + PE+ + + +Q ++Q+Q+E ++ QE+ R+
Sbjct: 465 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE--KIWEQEEKIRD 522
Query: 216 QQQL 219
Q+++
Sbjct: 523 QEEM 526
Score = 33.1 bits (74), Expect = 0.36
Identities = 23/84 (27%), Positives = 48/84 (57%), Gaps = 9/84 (10%)
Query: 142 IWEDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQ 201
IWE E E +R + ++R Q +K R EE++R E M+ ++ K+ Q+ ++ Q+
Sbjct: 789 IWEQE--EKMRDQEEKMRGQEEKMRGQ----EEKMRGQEEKMWGQEEKMWGQEEKMWGQE 842
Query: 202 EQV---RLLHQEKLEREQQQLRTQ 222
E++ +EK++ +++++R Q
Sbjct: 843 EKMWGQEEKMEEKMQGQEEKMREQ 866
>gi|32967514 neurofibromin 2 isoform 7 [Homo sapiens]
Length = 507
Score = 50.4 bits (119), Expect = 2e-06
Identities = 57/296 (19%), Positives = 136/296 (45%), Gaps = 21/296 (7%)
Query: 48 IRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLL 107
+RR A+S E ++M++ ++ K + + ++L++ +++ AE + ++ + RLL
Sbjct: 225 MRRRKADSLEVQQMKAQAREEKARKQM----ERQRLAREKQMREEAER--TRDELERRLL 278
Query: 108 QQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERS 167
Q +E + ++ R+E+ + + +E+A+ L ++ E Q++ + ++
Sbjct: 279 QMK-------EEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKA 331
Query: 168 VRMMLEEQVRSLEAHMYPEK---LKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRTQLL 224
+ EE+ R +E + + LK+ + + ++ +Q++ QE E E++ + L
Sbjct: 332 TAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLE 391
Query: 225 PPPAPTHHPTVIVPAPPPPPSHHINVVTMGPSSVINSVSTSRQNLDTIVQAIQHIEGTQE 284
PT+ P +PAP PP N++ S R +++ + ++++E ++
Sbjct: 392 IATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKH 451
Query: 285 KQELEEEQRRAVIVKPVRSCPEAPTSDTASDSEASD--SDAMDQSREEPSGDGELP 338
QE E + + ++ E T+ +E SD + + ++P G P
Sbjct: 452 LQEQLNELKTEIEALKLK---ERETALDILHNENSDRGGSSKHNTIKKPQAQGRRP 504
>gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 50.4 bits (119), Expect = 2e-06
Identities = 57/296 (19%), Positives = 136/296 (45%), Gaps = 21/296 (7%)
Query: 48 IRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLL 107
+RR A+S E ++M++ ++ K + + ++L++ +++ AE + ++ + RLL
Sbjct: 308 MRRRKADSLEVQQMKAQAREEKARKQM----ERQRLAREKQMREEAER--TRDELERRLL 361
Query: 108 QQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERS 167
Q +E + ++ R+E+ + + +E+A+ L ++ E Q++ + ++
Sbjct: 362 QMK-------EEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKA 414
Query: 168 VRMMLEEQVRSLEAHMYPEK---LKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRTQLL 224
+ EE+ R +E + + LK+ + + ++ +Q++ QE E E++ + L
Sbjct: 415 TAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLE 474
Query: 225 PPPAPTHHPTVIVPAPPPPPSHHINVVTMGPSSVINSVSTSRQNLDTIVQAIQHIEGTQE 284
PT+ P +PAP PP N++ S R +++ + ++++E ++
Sbjct: 475 IATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKH 534
Query: 285 KQELEEEQRRAVIVKPVRSCPEAPTSDTASDSEASD--SDAMDQSREEPSGDGELP 338
QE E + + ++ E T+ +E SD + + ++P G P
Sbjct: 535 LQEQLNELKTEIEALKLK---ERETALDILHNENSDRGGSSKHNTIKKPQAQGRRP 587
>gi|32967266 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 50.4 bits (119), Expect = 2e-06
Identities = 57/296 (19%), Positives = 136/296 (45%), Gaps = 21/296 (7%)
Query: 48 IRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLL 107
+RR A+S E ++M++ ++ K + + ++L++ +++ AE + ++ + RLL
Sbjct: 308 MRRRKADSLEVQQMKAQAREEKARKQM----ERQRLAREKQMREEAER--TRDELERRLL 361
Query: 108 QQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERS 167
Q +E + ++ R+E+ + + +E+A+ L ++ E Q++ + ++
Sbjct: 362 QMK-------EEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKA 414
Query: 168 VRMMLEEQVRSLEAHMYPEK---LKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRTQLL 224
+ EE+ R +E + + LK+ + + ++ +Q++ QE E E++ + L
Sbjct: 415 TAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLE 474
Query: 225 PPPAPTHHPTVIVPAPPPPPSHHINVVTMGPSSVINSVSTSRQNLDTIVQAIQHIEGTQE 284
PT+ P +PAP PP N++ S R +++ + ++++E ++
Sbjct: 475 IATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKH 534
Query: 285 KQELEEEQRRAVIVKPVRSCPEAPTSDTASDSEASD--SDAMDQSREEPSGDGELP 338
QE E + + ++ E T+ +E SD + + ++P G P
Sbjct: 535 LQEQLNELKTEIEALKLK---ERETALDILHNENSDRGGSSKHNTIKKPQAQGRRP 587
>gi|32967264 neurofibromin 2 isoform 7 [Homo sapiens]
Length = 507
Score = 50.4 bits (119), Expect = 2e-06
Identities = 57/296 (19%), Positives = 136/296 (45%), Gaps = 21/296 (7%)
Query: 48 IRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLL 107
+RR A+S E ++M++ ++ K + + ++L++ +++ AE + ++ + RLL
Sbjct: 225 MRRRKADSLEVQQMKAQAREEKARKQM----ERQRLAREKQMREEAER--TRDELERRLL 278
Query: 108 QQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERS 167
Q +E + ++ R+E+ + + +E+A+ L ++ E Q++ + ++
Sbjct: 279 QMK-------EEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKA 331
Query: 168 VRMMLEEQVRSLEAHMYPEK---LKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRTQLL 224
+ EE+ R +E + + LK+ + + ++ +Q++ QE E E++ + L
Sbjct: 332 TAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLE 391
Query: 225 PPPAPTHHPTVIVPAPPPPPSHHINVVTMGPSSVINSVSTSRQNLDTIVQAIQHIEGTQE 284
PT+ P +PAP PP N++ S R +++ + ++++E ++
Sbjct: 392 IATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKH 451
Query: 285 KQELEEEQRRAVIVKPVRSCPEAPTSDTASDSEASD--SDAMDQSREEPSGDGELP 338
QE E + + ++ E T+ +E SD + + ++P G P
Sbjct: 452 LQEQLNELKTEIEALKLK---ERETALDILHNENSDRGGSSKHNTIKKPQAQGRRP 504
>gi|32967262 neurofibromin 2 isoform 6 [Homo sapiens]
Length = 549
Score = 50.4 bits (119), Expect = 2e-06
Identities = 57/296 (19%), Positives = 136/296 (45%), Gaps = 21/296 (7%)
Query: 48 IRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLL 107
+RR A+S E ++M++ ++ K + + ++L++ +++ AE + ++ + RLL
Sbjct: 267 MRRRKADSLEVQQMKAQAREEKARKQM----ERQRLAREKQMREEAER--TRDELERRLL 320
Query: 108 QQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERS 167
Q +E + ++ R+E+ + + +E+A+ L ++ E Q++ + ++
Sbjct: 321 QMK-------EEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKA 373
Query: 168 VRMMLEEQVRSLEAHMYPEK---LKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRTQLL 224
+ EE+ R +E + + LK+ + + ++ +Q++ QE E E++ + L
Sbjct: 374 TAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLE 433
Query: 225 PPPAPTHHPTVIVPAPPPPPSHHINVVTMGPSSVINSVSTSRQNLDTIVQAIQHIEGTQE 284
PT+ P +PAP PP N++ S R +++ + ++++E ++
Sbjct: 434 IATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKH 493
Query: 285 KQELEEEQRRAVIVKPVRSCPEAPTSDTASDSEASD--SDAMDQSREEPSGDGELP 338
QE E + + ++ E T+ +E SD + + ++P G P
Sbjct: 494 LQEQLNELKTEIEALKLK---ERETALDILHNENSDRGGSSKHNTIKKPQAQGRRP 546
>gi|32967260 neurofibromin 2 isoform 5 [Homo sapiens]
Length = 548
Score = 50.4 bits (119), Expect = 2e-06
Identities = 57/296 (19%), Positives = 136/296 (45%), Gaps = 21/296 (7%)
Query: 48 IRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLL 107
+RR A+S E ++M++ ++ K + + ++L++ +++ AE + ++ + RLL
Sbjct: 266 MRRRKADSLEVQQMKAQAREEKARKQM----ERQRLAREKQMREEAER--TRDELERRLL 319
Query: 108 QQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERS 167
Q +E + ++ R+E+ + + +E+A+ L ++ E Q++ + ++
Sbjct: 320 QMK-------EEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKA 372
Query: 168 VRMMLEEQVRSLEAHMYPEK---LKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRTQLL 224
+ EE+ R +E + + LK+ + + ++ +Q++ QE E E++ + L
Sbjct: 373 TAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLE 432
Query: 225 PPPAPTHHPTVIVPAPPPPPSHHINVVTMGPSSVINSVSTSRQNLDTIVQAIQHIEGTQE 284
PT+ P +PAP PP N++ S R +++ + ++++E ++
Sbjct: 433 IATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKH 492
Query: 285 KQELEEEQRRAVIVKPVRSCPEAPTSDTASDSEASD--SDAMDQSREEPSGDGELP 338
QE E + + ++ E T+ +E SD + + ++P G P
Sbjct: 493 LQEQLNELKTEIEALKLK---ERETALDILHNENSDRGGSSKHNTIKKPQAQGRRP 545
>gi|32451486 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 50.4 bits (119), Expect = 2e-06
Identities = 57/296 (19%), Positives = 136/296 (45%), Gaps = 21/296 (7%)
Query: 48 IRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLL 107
+RR A+S E ++M++ ++ K + + ++L++ +++ AE + ++ + RLL
Sbjct: 308 MRRRKADSLEVQQMKAQAREEKARKQM----ERQRLAREKQMREEAER--TRDELERRLL 361
Query: 108 QQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERS 167
Q +E + ++ R+E+ + + +E+A+ L ++ E Q++ + ++
Sbjct: 362 QMK-------EEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKA 414
Query: 168 VRMMLEEQVRSLEAHMYPEK---LKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRTQLL 224
+ EE+ R +E + + LK+ + + ++ +Q++ QE E E++ + L
Sbjct: 415 TAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLE 474
Query: 225 PPPAPTHHPTVIVPAPPPPPSHHINVVTMGPSSVINSVSTSRQNLDTIVQAIQHIEGTQE 284
PT+ P +PAP PP N++ S R +++ + ++++E ++
Sbjct: 475 IATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKH 534
Query: 285 KQELEEEQRRAVIVKPVRSCPEAPTSDTASDSEASD--SDAMDQSREEPSGDGELP 338
QE E + + ++ E T+ +E SD + + ++P G P
Sbjct: 535 LQEQLNELKTEIEALKLK---ERETALDILHNENSDRGGSSKHNTIKKPQAQGRRP 587
>gi|14602437 Williams Beuren syndrome chromosome region 14 isoform
gamma [Homo sapiens]
Length = 850
Score = 50.1 bits (118), Expect = 3e-06
Identities = 31/85 (36%), Positives = 48/85 (56%), Gaps = 3/85 (3%)
Query: 42 RDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGE---KLSKAAILQQTAEYIFS 98
R + RR S E++R +I GF +L L+ + K+SKA LQ+TAEYI
Sbjct: 641 RPDSNKNRRITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYILM 700
Query: 99 LEQEKTRLLQQNTQLKRFIQELSGS 123
L+QE+ L ++ QL+ I+EL+ +
Sbjct: 701 LQQERAGLQEEAQQLRDEIEELNAA 725
>gi|4557795 neurofibromin 2 isoform 1 [Homo sapiens]
Length = 595
Score = 50.1 bits (118), Expect = 3e-06
Identities = 49/252 (19%), Positives = 120/252 (47%), Gaps = 16/252 (6%)
Query: 48 IRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLL 107
+RR A+S E ++M++ ++ K + + ++L++ +++ AE + ++ + RLL
Sbjct: 308 MRRRKADSLEVQQMKAQAREEKARKQM----ERQRLAREKQMREEAER--TRDELERRLL 361
Query: 108 QQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERS 167
Q +E + ++ R+E+ + + +E+A+ L ++ E Q++ + ++
Sbjct: 362 QMK-------EEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKA 414
Query: 168 VRMMLEEQVRSLEAHMYPEK---LKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRTQLL 224
+ EE+ R +E + + LK+ + + ++ +Q++ QE E E++ + L
Sbjct: 415 TAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLE 474
Query: 225 PPPAPTHHPTVIVPAPPPPPSHHINVVTMGPSSVINSVSTSRQNLDTIVQAIQHIEGTQE 284
PT+ P +PAP PP N++ S R +++ + ++++E ++
Sbjct: 475 IATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKH 534
Query: 285 KQELEEEQRRAV 296
QE E + +
Sbjct: 535 LQEQLNELKTEI 546
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 49.7 bits (117), Expect = 4e-06
Identities = 44/187 (23%), Positives = 90/187 (48%), Gaps = 14/187 (7%)
Query: 39 ETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFS 98
+ +R+Q+ R +++ + RR Q + Q + E+ + Q+ E
Sbjct: 394 QLRREQQLRREQQLRREQQLRREQQLRREQQ-----LRREQEEERHEQKHEQERREQRLK 448
Query: 99 LEQEKTR-LLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIE 157
EQE+ R L++ + +R QE KR + E++ E + E+E+ E R +
Sbjct: 449 REQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLE--EEERREQQERREQQ 506
Query: 158 LRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQ 217
LR++ ++ R R+ +E+ L+ + E QQ++ +Q++ + +LL +E+ +R +Q
Sbjct: 507 LRREQEERREQRLKRQEEEERLQQRLRSE------QQLRREQEERREQLLKREEEKRLEQ 560
Query: 218 QLRTQLL 224
+ R Q L
Sbjct: 561 ERREQRL 567
Score = 49.7 bits (117), Expect = 4e-06
Identities = 49/193 (25%), Positives = 93/193 (48%), Gaps = 33/193 (17%)
Query: 39 ETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFS 98
E Q+++E+ +R E E+RR+Q ++ + L QQ E +
Sbjct: 1025 ELQQEEEQLLREE----REKRRLQERERQYREEEEL---------------QQEEEQLLG 1065
Query: 99 LE------QEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLR 152
E QE R ++ +L++ ++L P++RR ++++ + + E+ E L
Sbjct: 1066 EERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEE-EQLL 1124
Query: 153 REMIELRQQLDKERSVRMMLEEQVRSLEAHMY---PEKLKVIAQQVQLQQQQEQVRLLHQ 209
RE E R++ + ER R EE+V+ E + PEK + Q+++ Q ++E+ +
Sbjct: 1125 REEREKRRRQELERQYRE--EEEVQQEEEQLLREEPEKRR--RQELERQYREEEELQQEE 1180
Query: 210 EKLEREQQQLRTQ 222
E+L RE+Q+ R Q
Sbjct: 1181 EQLLREEQEKRRQ 1193
Score = 49.3 bits (116), Expect = 5e-06
Identities = 42/147 (28%), Positives = 75/147 (51%), Gaps = 16/147 (10%)
Query: 89 LQQTAEYIFSLEQEKTRLLQQNTQ------LKRFIQELSGSSPKRRRAEDKDEGIGSPDI 142
LQQ E + E+EK R ++ Q L++ ++L G P++RR +++++ +
Sbjct: 936 LQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEE 995
Query: 143 WEDEKAEDLRREMIELRQQLDKERSVR-----MMLEEQV--RSLEAHMYPEKLKVIAQQV 195
+ E+ E L RE E R++ + ER R EEQ+ E E+ + ++
Sbjct: 996 LQQEE-EQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEE 1054
Query: 196 QLQQQQEQVRLLHQEKLEREQQQLRTQ 222
+LQQ++EQ LL +E+ R +Q+L Q
Sbjct: 1055 ELQQEEEQ--LLGEERETRRRQELERQ 1079
Score = 47.8 bits (112), Expect = 1e-05
Identities = 58/271 (21%), Positives = 115/271 (42%), Gaps = 28/271 (10%)
Query: 34 IPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTA 93
+ L E +R+Q+ R +++ E RR Q + + E+L + ++
Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKR----------QEEEERLQQRL---RSE 535
Query: 94 EYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRR 153
+ + ++E+ L + + KR QE KR + E +D+ + E+ + + L+R
Sbjct: 536 QQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKRE---EERRQQRLKR 592
Query: 154 EMIE-LRQQLDKERSVRMMLEEQVRSLEAHMYPE---KLKVIAQQVQLQQQQEQVRLLHQ 209
E E L Q+L +E R+ EE+ PE + +++ + Q +++Q+Q+R Q
Sbjct: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ 652
Query: 210 E------KLEREQQQLRTQLLPPPAPTHHPTVIVPAPPPPPSHHINVVTMGPSSVINSVS 263
E K E E+++L +L + I + S +
Sbjct: 653 ERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEA 712
Query: 264 TSRQNLDTIVQAIQHIEGTQEKQELEEEQRR 294
+RQ+ + + EG + +QE EE++RR
Sbjct: 713 DARQS--KVYSRPRKQEGQRRRQEQEEKRRR 741
Score = 47.4 bits (111), Expect = 2e-05
Identities = 46/190 (24%), Positives = 86/190 (45%), Gaps = 13/190 (6%)
Query: 39 ETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFS 98
+ +R+++ R+ +E R+R + + L+ P E LQ+ E +
Sbjct: 228 QQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE-------LQEEEEQLRK 280
Query: 99 LEQEKTRLL----QQNTQLKRFIQELSGSSPKRRRA--EDKDEGIGSPDIWEDEKAEDLR 152
LE+++ R +Q Q R Q+L + RR E++ E + E+ + + LR
Sbjct: 281 LERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLR 340
Query: 153 REMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKL 212
RE E R+Q + E+Q+R + E+ QQ++ +QQ + + L +E+
Sbjct: 341 REQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQ 400
Query: 213 EREQQQLRTQ 222
R +QQLR +
Sbjct: 401 LRREQQLRRE 410
Score = 47.4 bits (111), Expect = 2e-05
Identities = 49/194 (25%), Positives = 95/194 (48%), Gaps = 21/194 (10%)
Query: 42 RDQERRIRREIANSNERRRMQSINA-----GFQSLKTLIPHTDGEKLSKAAILQQTAEYI 96
R +E+++RR+ ER+ M+ G Q L+ D + +LQ+ E
Sbjct: 1582 RLEEQKVRRQ---EQERKFMEDEQQLRRQEGQQQLRQ---ERDRKFREDEQLLQEREEQQ 1635
Query: 97 FSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPD---IWEDEKAEDLRR 153
++ + L++ QL+R +E + R+ ++++ + + + E+ R
Sbjct: 1636 LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFRE 1695
Query: 154 EMIELRQQLDKERSVRMMLEEQVRSLEAH---MYPEKLKVIAQQVQLQQQQEQVRLLHQE 210
E +LR+Q ++ER + E+Q+R E E+L+ +Q QL++Q+ ++L +E
Sbjct: 1696 EEQQLRRQ-ERERKF-LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEE 1753
Query: 211 KL--EREQQQLRTQ 222
+L ERE+QQLR Q
Sbjct: 1754 QLRPEREEQQLRRQ 1767
Score = 46.2 bits (108), Expect = 4e-05
Identities = 46/186 (24%), Positives = 87/186 (46%), Gaps = 25/186 (13%)
Query: 44 QERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEK 103
+E+++RR+ ++R Q + F+ + L + ++LS+ Q + F LE++K
Sbjct: 1536 EEQQLRRQ---ERGQQRRQDRDRKFREEEQLRQEREEQQLSR-----QERDRKFRLEEQK 1587
Query: 104 TRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLD 163
R +Q + Q+L +++ +++D EDE+ R E QQL
Sbjct: 1588 VRRQEQERKFMEDEQQLRRQEGQQQLRQERDR-----KFREDEQLLQEREE-----QQLH 1637
Query: 164 KERSVRMMLEEQV----RSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQE---KLEREQ 216
++ R LEE+ + E + ++ + ++ QL Q+ E+ +L QE K E+
Sbjct: 1638 RQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEE 1697
Query: 217 QQLRTQ 222
QQLR Q
Sbjct: 1698 QQLRRQ 1703
Score = 45.1 bits (105), Expect = 9e-05
Identities = 49/204 (24%), Positives = 92/204 (45%), Gaps = 36/204 (17%)
Query: 39 ETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFS 98
ET+R ++ R ++++ E R + + + E+ + Q+ E
Sbjct: 463 ETERHEQERRKQQLKRDQEEERRER----------WLKLEEEERREQ----QERREQQLR 508
Query: 99 LEQEKTR--LLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAED------ 150
EQE+ R L++ + +R Q L RR E++ E + + E+++ E
Sbjct: 509 REQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKRE--EEKRLEQERREQR 566
Query: 151 LRREMIELRQQL---DKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQ-------- 199
L+RE E R QL ++ER + + EQ LE + E+++ + Q+ + +Q
Sbjct: 567 LKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPE 626
Query: 200 -QQEQVRLLHQEKLEREQQQLRTQ 222
++ Q L +E+ ER QQQLR +
Sbjct: 627 EERRQQLLKSEEQEERRQQQLRRE 650
Score = 44.3 bits (103), Expect = 2e-04
Identities = 43/166 (25%), Positives = 74/166 (44%), Gaps = 43/166 (25%)
Query: 100 EQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIW---------EDEKAED 150
E+ R Q+ + +R + E S K+ R E +D ++W E+ +AE+
Sbjct: 131 EEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEE 190
Query: 151 --------------------LRREMIELR-------QQLDKERSVRMMLEEQV---RSLE 180
RRE++ELR QQ +ER R+ EE+ R E
Sbjct: 191 EQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRE 250
Query: 181 AHMYPEKLKVIAQQVQ----LQQQQEQVRLLHQEKLEREQQQLRTQ 222
+ E+ K+ ++ Q LQ+++EQ+R L +++L RE+Q+ Q
Sbjct: 251 TVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQ 296
Score = 43.9 bits (102), Expect = 2e-04
Identities = 41/185 (22%), Positives = 84/185 (45%), Gaps = 4/185 (2%)
Query: 36 LTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEY 95
L E ++ QE +R+ E +++ + + ++L + L++ E
Sbjct: 253 LRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE 312
Query: 96 IFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREM 155
+QE+ R Q+ +R QE RR E++ E + E+ + + LRRE
Sbjct: 313 ERREQQEERREQQE----RREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368
Query: 156 IELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLERE 215
E R++ R ++ E+Q+R + ++L+ Q + QQ + + +L +++L RE
Sbjct: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428
Query: 216 QQQLR 220
Q++ R
Sbjct: 429 QEEER 433
Score = 43.9 bits (102), Expect = 2e-04
Identities = 42/188 (22%), Positives = 94/188 (50%), Gaps = 27/188 (14%)
Query: 42 RDQERRIRRE-----IANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYI 96
R++E+++RR+ ++ R Q + F+ + L T+ E+L ++ Y
Sbjct: 1694 REEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL------RRQERYR 1747
Query: 97 FSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMI 156
LE+E+ R ++ QL+R ++ ++ R E +++ + S ++++ RE
Sbjct: 1748 KILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRS------QESDRKFREEE 1801
Query: 157 ELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQE-----QVRLLHQEK 211
+LRQ+ ++++ L Q R + E+L++ Q+ +L+Q+++ + + QEK
Sbjct: 1802 QLRQEREEQQ-----LRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEK 1856
Query: 212 LEREQQQL 219
RE+Q+L
Sbjct: 1857 SRREEQEL 1864
Score = 42.4 bits (98), Expect = 6e-04
Identities = 53/189 (28%), Positives = 81/189 (42%), Gaps = 33/189 (17%)
Query: 41 QRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLE 100
Q DQERR S E+RR Q + + HT L LQ+ L
Sbjct: 857 QEDQERR------RSQEQRRDQKWRWQLEEERKRRRHT----LYAKPALQEQLRKEQQLL 906
Query: 101 QEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQ 160
QE+ LQ+ + KRRR E + + + ++E E L RE E R+
Sbjct: 907 QEEEEELQREER------------EKRRRQEQERQYREEEQLQQEE--EQLLREEREKRR 952
Query: 161 QLDKERSVR-----MMLEEQV--RSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLE 213
+ ++ER R EEQ+ E E+ K ++ +LQQ++EQ LL +E+ +
Sbjct: 953 RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQ--LLREEREK 1010
Query: 214 REQQQLRTQ 222
R +Q+ Q
Sbjct: 1011 RRRQEWERQ 1019
Score = 41.6 bits (96), Expect = 0.001
Identities = 39/180 (21%), Positives = 84/180 (46%), Gaps = 14/180 (7%)
Query: 43 DQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQE 102
++E+R+RR+ + Q + + + + + + +Q + F E++
Sbjct: 1378 EEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQ 1437
Query: 103 KTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQL 162
+ R ++ ++F++E +R R ++E + + ++ R+ +E QQL
Sbjct: 1438 QVRRQERE---RKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQL 1494
Query: 163 DKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRTQ 222
++ R E+++RS E PE+ K + ++ QL +QQ Q + L +E+QQLR Q
Sbjct: 1495 RRQERDRKFREQELRSQE----PER-KFLEEEQQLHRQQRQRKFL------QEEQQLRRQ 1543
Score = 40.8 bits (94), Expect = 0.002
Identities = 47/202 (23%), Positives = 88/202 (43%), Gaps = 40/202 (19%)
Query: 39 ETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFS 98
E Q+++E+ +R E E+RR Q + ++ + L QQ E +
Sbjct: 1145 EVQQEEEQLLREE----PEKRRRQELERQYREEEEL---------------QQEEEQLLR 1185
Query: 99 LEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLR------ 152
EQEK R Q+ + R +EL +++R D+D+ WE EK +R
Sbjct: 1186 EEQEKRR--QERERQYREEEELQRQK-RKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYC 1242
Query: 153 --REMIELRQQLDKE-------RSVRMMLEEQV---RSLEAHMYPEKLKVIAQQVQLQQQ 200
RE + RQ D + + ++ +L EQ R E + ++ + ++ QL+++
Sbjct: 1243 KGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLERE 1302
Query: 201 QEQVRLLHQEKLEREQQQLRTQ 222
+++ K + E+Q LR +
Sbjct: 1303 EQKEAKRRDRKSQEEKQLLREE 1324
Score = 40.8 bits (94), Expect = 0.002
Identities = 38/186 (20%), Positives = 78/186 (41%), Gaps = 23/186 (12%)
Query: 39 ETQRDQERRI--RREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYI 96
++Q+D + + ++E ERRR Q + F + L E + Q+ + +
Sbjct: 1262 QSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLL 1321
Query: 97 FSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMI 156
+EK R + + + + Q L + R +++D ++ E+ R+ +
Sbjct: 1322 REEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQG----RKFL 1377
Query: 157 ELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQ 216
E Q+L ++ R L+E+ QQ++ Q++++Q+R K E+
Sbjct: 1378 EEEQRLRRQERERKFLKEE-----------------QQLRCQEREQQLRQDRDRKFREEE 1420
Query: 217 QQLRTQ 222
QQL Q
Sbjct: 1421 QQLSRQ 1426
Score = 40.4 bits (93), Expect = 0.002
Identities = 43/184 (23%), Positives = 84/184 (45%), Gaps = 8/184 (4%)
Query: 41 QRDQERRIRREIANSNER-RRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSL 99
+R + RR R+E +R RR Q + + + E+ + ++ E
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341
Query: 100 EQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELR 159
EQE+ R QL+R +E RR E++ + + + LRRE +LR
Sbjct: 342 EQEERR----EQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQ-QLR 396
Query: 160 QQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQL 219
++ R ++ E+Q+R + ++L+ ++ + +Q+ EQ R +++L+REQ++
Sbjct: 397 REQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQER--REQRLKREQEER 454
Query: 220 RTQL 223
R L
Sbjct: 455 RDWL 458
Score = 40.4 bits (93), Expect = 0.002
Identities = 43/184 (23%), Positives = 80/184 (43%), Gaps = 25/184 (13%)
Query: 39 ETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFS 98
E Q ++ R R+ + + RR Q + + H K + L Q E
Sbjct: 1633 EQQLHRQERDRKFLEEEPQLRR--------QEREQQLRHDRDRKFREEEQLLQEGEEQQL 1684
Query: 99 LEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIEL 158
QE+ R ++ Q R + R+ +++ + ++ + E+ R+ E
Sbjct: 1685 RRQERDRKFREEEQQLR-------RQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ 1737
Query: 159 RQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQ 218
Q +ER +++ EEQ+R PE+ + QQ++ Q++ + R Q + ERE+QQ
Sbjct: 1738 EQLRRQERYRKILEEEQLR-------PEREE---QQLRRQERDRKFREEEQLRQEREEQQ 1787
Query: 219 LRTQ 222
LR+Q
Sbjct: 1788 LRSQ 1791
Score = 39.7 bits (91), Expect = 0.004
Identities = 43/193 (22%), Positives = 94/193 (48%), Gaps = 14/193 (7%)
Query: 39 ETQRDQERRIRREIANSNERRRMQSINAGFQS-----LKTLIPHTDGEKLSKAAILQQTA 93
E + E+R++RE E RR Q + Q +K+ IP + L A +Q+
Sbjct: 663 EEEERLEQRLKRE---HEEERREQELAEEEQEQARERIKSRIPKWQWQ-LESEADARQSK 718
Query: 94 EYIFSLEQEKTRLLQQNTQLKRFIQ-ELSGSSPKR--RRAEDKDEGIGSPDIWEDEKAED 150
Y +QE R Q+ + +R + EL +R R+ +++++ W+ E+ +
Sbjct: 719 VYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSE 778
Query: 151 LRREMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQE 210
R+ + R L ++R ++ EE+ + E PE+ + ++ Q ++++++++ L +E
Sbjct: 779 RGRQRLSARPPLREQRERQLRAEER-QQREQRFLPEEEEKEQRRRQRREREKELQFLEEE 837
Query: 211 K-LEREQQQLRTQ 222
+ L+R ++ + Q
Sbjct: 838 EQLQRRERAQQLQ 850
Score = 39.3 bits (90), Expect = 0.005
Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 10/123 (8%)
Query: 100 EQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELR 159
++ + + LQ+ QL+R E ++ R E + E + + + E+ R E +
Sbjct: 1703 QERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQ 1762
Query: 160 QQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQL 219
Q +ER + EEQ+R QQ++ Q+ + R Q + ERE+QQL
Sbjct: 1763 QLRRQERDRKFREEEQLRQEREE----------QQLRSQESDRKFREEEQLRQEREEQQL 1812
Query: 220 RTQ 222
R Q
Sbjct: 1813 RPQ 1815
Score = 38.1 bits (87), Expect = 0.011
Identities = 50/199 (25%), Positives = 83/199 (41%), Gaps = 28/199 (14%)
Query: 39 ETQRDQERRIRREIANSNERR-----RMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTA 93
+ ++++ R+ R E ER R + + + L K + + Q
Sbjct: 1454 QLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEP 1513
Query: 94 EYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRR 153
E F E+++ Q+ + + Q+L ++R +D+D + + E LR+
Sbjct: 1514 ERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDR--------KFREEEQLRQ 1565
Query: 154 EMIELRQQLDK-ERSVRMMLEEQ-VRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEK 211
E E QQL + ER + LEEQ VR E K QQ++ Q+ Q+Q+R K
Sbjct: 1566 EREE--QQLSRQERDRKFRLEEQKVRRQEQE---RKFMEDEQQLRRQEGQQQLRQERDRK 1620
Query: 212 L--------EREQQQLRTQ 222
ERE+QQL Q
Sbjct: 1621 FREDEQLLQEREEQQLHRQ 1639
Score = 37.4 bits (85), Expect = 0.019
Identities = 41/203 (20%), Positives = 87/203 (42%), Gaps = 38/203 (18%)
Query: 38 PETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIF 97
P + +ER++R E E+R +P + ++ + ++ E F
Sbjct: 788 PPLREQRERQLRAEERQQREQR--------------FLPEEEEKEQRRRQRREREKELQF 833
Query: 98 SLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMI- 156
E+E+ LQ+ + ++ +E G + R +++ W+ E+ RR +
Sbjct: 834 LEEEEQ---LQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLY 890
Query: 157 ---ELRQQLDKERSVRMMLEEQVR--SLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEK 211
L++QL KE+ + EE+++ E E+ + ++ QLQQ++EQ+ +EK
Sbjct: 891 AKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREK 950
Query: 212 ---------------LEREQQQL 219
L+++++QL
Sbjct: 951 RRRQERERQYRKDKKLQQKEEQL 973
Score = 36.6 bits (83), Expect = 0.033
Identities = 38/172 (22%), Positives = 73/172 (42%), Gaps = 38/172 (22%)
Query: 89 LQQTAEYIFSLEQEKTRLLQ------QNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDI 142
LQQ E + E+EK R + + ++++ ++L P++RR ++ + +
Sbjct: 1116 LQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175
Query: 143 WEDEKAEDLRREMIELRQQLDKE-----------RSVRMMLEEQVRSLEAHMYPEKLKVI 191
+ E+ + LR E + RQ+ +++ R R E+Q L+ PEK +
Sbjct: 1176 LQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAV 1235
Query: 192 -----------------AQQVQLQQQQEQVRLLH----QEKLEREQQQLRTQ 222
+ QL+ +Q Q L H Q++ +REQ++ R Q
Sbjct: 1236 RDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQ 1287
Score = 34.7 bits (78), Expect = 0.12
Identities = 43/198 (21%), Positives = 87/198 (43%), Gaps = 22/198 (11%)
Query: 41 QRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLE 100
QRD++RR E + + A + L++ H E + + ++ +
Sbjct: 163 QRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKG 222
Query: 101 QEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQ 160
+E+ + ++ Q + F +E KR K+E + E+E +RE+ E +
Sbjct: 223 REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEE----EKLQEEEPQR--QRELQEEEE 276
Query: 161 QL--------------DKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVR- 205
QL ++++ R+ E+Q+R + E+ + +Q + ++QQE+ R
Sbjct: 277 QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE 336
Query: 206 -LLHQEKLEREQQQLRTQ 222
L +E+ ER +QQLR +
Sbjct: 337 QQLRREQEERREQQLRRE 354
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 49.3 bits (116), Expect = 5e-06
Identities = 37/184 (20%), Positives = 90/184 (48%), Gaps = 11/184 (5%)
Query: 41 QRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQ--QTAEYIFS 98
Q +Q ++ ++ E+ R Q G Q + +K + Q Q E
Sbjct: 211 QEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQ 270
Query: 99 LEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIEL 158
+ +++ ++L+Q Q ++ +E +G ++ R +++ ++E+ + +M E
Sbjct: 271 MREQEEQMLKQKEQTEQ--EEQTGEQEEQMREQEEQMRE------QEEQMREQEEQMREQ 322
Query: 159 RQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQ 218
+Q+ K+ +EQ+ + M+ ++ ++ Q+ Q+Q+Q+EQVR +E++ ++++Q
Sbjct: 323 EEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVR-KQEEQMRKQEEQ 381
Query: 219 LRTQ 222
+R Q
Sbjct: 382 MRKQ 385
Score = 44.3 bits (103), Expect = 2e-04
Identities = 40/186 (21%), Positives = 89/186 (47%), Gaps = 11/186 (5%)
Query: 39 ETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQ-QTAEYIF 97
+ Q +Q R+ ++ E+ R Q Q +T GE+ + + Q E
Sbjct: 251 QKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEE 310
Query: 98 SLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIW-EDEKAEDLRREMI 156
+ +++ ++ +Q Q+ + QE K + E K++ +W ++E+ + +M
Sbjct: 311 QMREQEEQMREQEEQMGK--QEEQMWEQKEQMWEQKEQ------MWKQEEQMGEQEEQMQ 362
Query: 157 ELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQ 216
+ +Q+ K+ EEQ+R E M ++ ++ Q+ Q+ +Q+EQ+R +E++ ++
Sbjct: 363 KQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMR-EQEEQMGEQK 421
Query: 217 QQLRTQ 222
+Q+R Q
Sbjct: 422 EQMRKQ 427
Score = 41.2 bits (95), Expect = 0.001
Identities = 22/69 (31%), Positives = 42/69 (60%), Gaps = 1/69 (1%)
Query: 154 EMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLE 213
+M E +Q+ K+ EEQ+R E M ++ +V Q+ Q+Q+Q+EQ+R +E++
Sbjct: 207 QMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMR-KQEEQMR 265
Query: 214 REQQQLRTQ 222
+++Q+R Q
Sbjct: 266 EQEEQMREQ 274
Score = 41.2 bits (95), Expect = 0.001
Identities = 33/179 (18%), Positives = 84/179 (46%), Gaps = 20/179 (11%)
Query: 39 ETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFS 98
+ Q +Q ++ ++ E+ R Q Q + L E+ +QT E
Sbjct: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQE------EQTGEQEEQ 297
Query: 99 LEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIEL 158
+ +++ ++ +Q Q++ +++ R +++ G +WE ++ +M E
Sbjct: 298 MREQEEQMREQEEQMREQEEQM--------REQEEQMGKQEEQMWEQKE------QMWEQ 343
Query: 159 RQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQ 217
++Q+ K+ EEQ++ E + ++ ++ Q+ Q+++Q+EQ+R ++ E+++Q
Sbjct: 344 KEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQ 402
Score = 38.1 bits (87), Expect = 0.011
Identities = 18/77 (23%), Positives = 44/77 (57%)
Query: 144 EDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQ 203
++E+ + +M + +Q+ ++ EEQ+ E + ++ +V Q+ Q+++Q+EQ
Sbjct: 204 QEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQ 263
Query: 204 VRLLHQEKLEREQQQLR 220
+R ++ E+E+Q L+
Sbjct: 264 MREQEEQMREQEEQMLK 280
Score = 37.4 bits (85), Expect = 0.019
Identities = 19/69 (27%), Positives = 42/69 (60%), Gaps = 1/69 (1%)
Query: 154 EMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLE 213
+M E +Q+ ++ EEQ+ E M ++ ++ Q+ Q+Q+Q+EQV+ +E++
Sbjct: 200 QMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQ-KQEEQMR 258
Query: 214 REQQQLRTQ 222
++++Q+R Q
Sbjct: 259 KQEEQMREQ 267
Score = 34.3 bits (77), Expect = 0.16
Identities = 18/79 (22%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
Query: 144 EDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQ 203
++ + + +M E Q+ ++ EEQ++ E M ++ ++ Q+ Q+ +Q+EQ
Sbjct: 183 QEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQ 242
Query: 204 VRLLHQEKLEREQQQLRTQ 222
V+ +E+++++++Q+R Q
Sbjct: 243 VQ-KQEEQVQKQEEQMRKQ 260
Score = 34.3 bits (77), Expect = 0.16
Identities = 25/132 (18%), Positives = 69/132 (52%), Gaps = 16/132 (12%)
Query: 91 QTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAED 150
Q E + +++ ++ +Q Q+++ +++ + R+ E++ +G + ++ E
Sbjct: 193 QMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQ---MGEQEEQVQKQEEQ 249
Query: 151 LRREMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQE 210
++++ ++R+Q EEQ+R E M ++ +++ Q+ Q +Q+EQ +E
Sbjct: 250 VQKQEEQMRKQ-----------EEQMREQEEQMREQEEQMLKQKEQT-EQEEQTG-EQEE 296
Query: 211 KLEREQQQLRTQ 222
++ +++Q+R Q
Sbjct: 297 QMREQEEQMREQ 308
Score = 30.4 bits (67), Expect = 2.4
Identities = 42/241 (17%), Positives = 111/241 (46%), Gaps = 26/241 (10%)
Query: 2 EYFMVPTQKVPSLQHFRKTEKEVIGGLCSLANIPLTPETQ-RDQERRIRREIANSNERR- 59
E +V T+K H ++ ++++ IPL E Q R+QE ++R + E+
Sbjct: 19 ELQLVETEKSEIQLHIKELKRKL-----ETDKIPLPQEGQVREQEGQVREQEGQVREQEG 73
Query: 60 RMQSINAGFQSLKTLIPHTDGEKLSKAAILQ----QTAEYIFSLEQEKTRLLQQNTQLKR 115
+++ + + + +G+ + ++ Q E + +++ ++ +Q Q++
Sbjct: 74 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 133
Query: 116 F---IQELSGSSPKRRRAEDKDEG-IGSPDIWEDEKAEDLRREMIELRQQLDKERSVRMM 171
++E G ++ + EG + + E+ +R + ++R+Q + R
Sbjct: 134 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 193
Query: 172 L----------EEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRT 221
+ EEQ+ E M ++ ++ Q+ Q+++Q+EQ+ +E+++++++Q++
Sbjct: 194 MGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMG-EQEEQVQKQEEQVQK 252
Query: 222 Q 222
Q
Sbjct: 253 Q 253
>gi|17981708 twist homolog 2 [Homo sapiens]
Length = 160
Score = 48.5 bits (114), Expect = 8e-06
Identities = 26/65 (40%), Positives = 38/65 (58%)
Query: 37 TPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYI 96
+P Q +E + +R +AN ER+R QS+N F +L+ +IP +KLSK L+ A YI
Sbjct: 55 SPSAQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYI 114
Query: 97 FSLEQ 101
L Q
Sbjct: 115 DFLYQ 119
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 48.5 bits (114), Expect = 8e-06
Identities = 58/211 (27%), Positives = 103/211 (48%), Gaps = 20/211 (9%)
Query: 15 QHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTL 74
Q FRK +E IG + + Q I+R+ ++ + R ++I A + K
Sbjct: 2404 QRFRKQAEE-IGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAI-AELEREK-- 2459
Query: 75 IPHTDGEKLSKAA-ILQQTAEYIFSLEQEKTRLLQQNTQLKR-FIQELSGSSPKRRRAED 132
EKL + A +LQ +E + +++QE+ LLQ+ L++ F+ E + R E
Sbjct: 2460 ------EKLQQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQ 2511
Query: 133 KDEGIGSPDIWEDE--KAEDLRREMIELRQQLDKERS--VRMMLEEQVRSLEAHMYPEKL 188
+ + +++DE KA+ LR E +QQ+++ER V M E + R EA +
Sbjct: 2512 EKAKL--EQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRK 2569
Query: 189 KVIAQQVQLQQQQEQVRLLHQEKLEREQQQL 219
+ QQ++ Q++Q++ L + + REQ QL
Sbjct: 2570 QEELQQLEQQRRQQEELLAEENQRLREQLQL 2600
Score = 46.6 bits (109), Expect = 3e-05
Identities = 41/197 (20%), Positives = 88/197 (44%), Gaps = 29/197 (14%)
Query: 41 QRDQERRIRREIANSNERRR--------MQSINAGFQSLKTLIPHTDGEKLSKAAILQQT 92
+R+ E R+++ +A E R ++ + A + + L + E + + Q+
Sbjct: 1983 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2042
Query: 93 AE---------YIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIW 143
A+ + F+++Q++ L Q Q + + +L G + RRA ++ E
Sbjct: 2043 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAE-------- 2094
Query: 144 EDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRS-LEAHMYPEKLKVIAQQVQLQQ-QQ 201
E RE + R+Q+++ ++ EEQ ++ +A EKL+ A+Q ++ Q
Sbjct: 2095 --EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA 2152
Query: 202 EQVRLLHQEKLEREQQQ 218
EQ L ++ + E ++
Sbjct: 2153 EQAALRQKQAADAEMEK 2169
Score = 35.0 bits (79), Expect = 0.096
Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 11/97 (11%)
Query: 126 KRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERSVRMMLE------EQVRSL 179
++++A+ + EG+G +AE +++ L + ++R LE EQVRSL
Sbjct: 1025 EQQKAQAEVEGLGKGVARLSAEAE----KVLALPEPSPAAPTLRSELELTLGKLEQVRSL 1080
Query: 180 EAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQ 216
A +Y EKLK I+ ++ Q E+V H+E+L+ Q
Sbjct: 1081 SA-IYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQ 1116
Score = 34.7 bits (78), Expect = 0.12
Identities = 48/229 (20%), Positives = 92/229 (40%), Gaps = 22/229 (9%)
Query: 9 QKVPSLQHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGF 68
Q + + RK ++ L + D E ++ A R++ Q +
Sbjct: 2130 QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQ-VEQEL 2188
Query: 69 QSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRR 128
+L+ + TD +K LQ+ ++++++ ++ ++ ++ELS R
Sbjct: 2189 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELS-KLKARI 2247
Query: 129 RAEDKDEGIGSPDIW------EDEKAEDLRREMIELRQQLDKERSVRMMLEE---QVRSL 179
AE++ + D E EK + + E L + +R + EE Q R+L
Sbjct: 2248 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2307
Query: 180 EAHMYPEKLKVIAQQVQL-------QQQ----QEQVRLLHQEKLEREQQ 217
M EK++ + + +L QQQ QEQ R L ++K + QQ
Sbjct: 2308 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQ 2356
Score = 33.1 bits (74), Expect = 0.36
Identities = 39/191 (20%), Positives = 80/191 (41%), Gaps = 22/191 (11%)
Query: 42 RDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQ 101
+++ R+RR++ + ++R+R + L + + K LQ E E+
Sbjct: 1493 QEEAERLRRQVQDESQRKRQAEV-----ELASRVKAEAEAAREKQRALQALEELRLQAEE 1547
Query: 102 EKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPD--------IWEDEKAEDLRR 153
+ RL Q + R +Q ++ + AE + + + + E+ A R
Sbjct: 1548 AERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLR 1607
Query: 154 EMIELRQQLD------KERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLL 207
E E R Q +E + R + Q+++ EA + + +AQQ L Q + + +
Sbjct: 1608 EEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQ-- 1665
Query: 208 HQEKLEREQQQ 218
+E+ ERE ++
Sbjct: 1666 -KEEAEREARR 1675
Score = 30.0 bits (66), Expect = 3.1
Identities = 43/186 (23%), Positives = 74/186 (39%), Gaps = 19/186 (10%)
Query: 47 RIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRL 106
++R+E A RR Q+ A + + D E +QT +EQE T L
Sbjct: 2137 KLRKE-AEQEAARRAQAEQAALRQKQA----ADAEMEKHKKFAEQTLRQKAQVEQELTTL 2191
Query: 107 L-------QQNTQLKRFIQELSGSSPKRRRAEDK-DEGIGSPDIWEDEKAEDLRREMIEL 158
Q L +Q L + + R + +E + S + +E ++ R E
Sbjct: 2192 RLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAEN 2251
Query: 159 RQQL--DKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQ----EKL 212
R + DK+ + R + EE + + +L V AQ+ +Q + L Q EK+
Sbjct: 2252 RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKM 2311
Query: 213 EREQQQ 218
+E+ Q
Sbjct: 2312 LKEKMQ 2317
Score = 29.3 bits (64), Expect = 5.2
Identities = 38/217 (17%), Positives = 78/217 (35%), Gaps = 20/217 (9%)
Query: 18 RKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPH 77
R E E+ S A E +E ++ ERR Q A
Sbjct: 1572 RSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERA-------R 1624
Query: 78 TDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGI 137
+ E+ + L+ L+ E+ + Q + Q+ RRR + +++ +
Sbjct: 1625 EEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1684
Query: 138 GSPDIWEDEKAEDLR-------------REMIELRQQLDKERSVRMMLEEQVRSLEAHMY 184
++ E E + + +E+I LR + ++ R +LEE++ L+
Sbjct: 1685 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1744
Query: 185 PEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRT 221
K + +L + + ++ +L K E++ T
Sbjct: 1745 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRST 1781
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 48.5 bits (114), Expect = 8e-06
Identities = 58/211 (27%), Positives = 103/211 (48%), Gaps = 20/211 (9%)
Query: 15 QHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTL 74
Q FRK +E IG + + Q I+R+ ++ + R ++I A + K
Sbjct: 2408 QRFRKQAEE-IGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAI-AELEREK-- 2463
Query: 75 IPHTDGEKLSKAA-ILQQTAEYIFSLEQEKTRLLQQNTQLKR-FIQELSGSSPKRRRAED 132
EKL + A +LQ +E + +++QE+ LLQ+ L++ F+ E + R E
Sbjct: 2464 ------EKLQQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQ 2515
Query: 133 KDEGIGSPDIWEDE--KAEDLRREMIELRQQLDKERS--VRMMLEEQVRSLEAHMYPEKL 188
+ + +++DE KA+ LR E +QQ+++ER V M E + R EA +
Sbjct: 2516 EKAKL--EQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRK 2573
Query: 189 KVIAQQVQLQQQQEQVRLLHQEKLEREQQQL 219
+ QQ++ Q++Q++ L + + REQ QL
Sbjct: 2574 QEELQQLEQQRRQQEELLAEENQRLREQLQL 2604
Score = 46.6 bits (109), Expect = 3e-05
Identities = 41/197 (20%), Positives = 88/197 (44%), Gaps = 29/197 (14%)
Query: 41 QRDQERRIRREIANSNERRR--------MQSINAGFQSLKTLIPHTDGEKLSKAAILQQT 92
+R+ E R+++ +A E R ++ + A + + L + E + + Q+
Sbjct: 1987 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2046
Query: 93 AE---------YIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIW 143
A+ + F+++Q++ L Q Q + + +L G + RRA ++ E
Sbjct: 2047 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAE-------- 2098
Query: 144 EDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRS-LEAHMYPEKLKVIAQQVQLQQ-QQ 201
E RE + R+Q+++ ++ EEQ ++ +A EKL+ A+Q ++ Q
Sbjct: 2099 --EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA 2156
Query: 202 EQVRLLHQEKLEREQQQ 218
EQ L ++ + E ++
Sbjct: 2157 EQAALRQKQAADAEMEK 2173
Score = 35.0 bits (79), Expect = 0.096
Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 11/97 (11%)
Query: 126 KRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERSVRMMLE------EQVRSL 179
++++A+ + EG+G +AE +++ L + ++R LE EQVRSL
Sbjct: 1029 EQQKAQAEVEGLGKGVARLSAEAE----KVLALPEPSPAAPTLRSELELTLGKLEQVRSL 1084
Query: 180 EAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQ 216
A +Y EKLK I+ ++ Q E+V H+E+L+ Q
Sbjct: 1085 SA-IYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQ 1120
Score = 34.7 bits (78), Expect = 0.12
Identities = 48/229 (20%), Positives = 92/229 (40%), Gaps = 22/229 (9%)
Query: 9 QKVPSLQHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGF 68
Q + + RK ++ L + D E ++ A R++ Q +
Sbjct: 2134 QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQ-VEQEL 2192
Query: 69 QSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRR 128
+L+ + TD +K LQ+ ++++++ ++ ++ ++ELS R
Sbjct: 2193 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELS-KLKARI 2251
Query: 129 RAEDKDEGIGSPDIW------EDEKAEDLRREMIELRQQLDKERSVRMMLEE---QVRSL 179
AE++ + D E EK + + E L + +R + EE Q R+L
Sbjct: 2252 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2311
Query: 180 EAHMYPEKLKVIAQQVQL-------QQQ----QEQVRLLHQEKLEREQQ 217
M EK++ + + +L QQQ QEQ R L ++K + QQ
Sbjct: 2312 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQ 2360
Score = 33.1 bits (74), Expect = 0.36
Identities = 39/191 (20%), Positives = 80/191 (41%), Gaps = 22/191 (11%)
Query: 42 RDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQ 101
+++ R+RR++ + ++R+R + L + + K LQ E E+
Sbjct: 1497 QEEAERLRRQVQDESQRKRQAEV-----ELASRVKAEAEAAREKQRALQALEELRLQAEE 1551
Query: 102 EKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPD--------IWEDEKAEDLRR 153
+ RL Q + R +Q ++ + AE + + + + E+ A R
Sbjct: 1552 AERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLR 1611
Query: 154 EMIELRQQLD------KERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLL 207
E E R Q +E + R + Q+++ EA + + +AQQ L Q + + +
Sbjct: 1612 EEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQ-- 1669
Query: 208 HQEKLEREQQQ 218
+E+ ERE ++
Sbjct: 1670 -KEEAEREARR 1679
Score = 30.0 bits (66), Expect = 3.1
Identities = 43/186 (23%), Positives = 74/186 (39%), Gaps = 19/186 (10%)
Query: 47 RIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRL 106
++R+E A RR Q+ A + + D E +QT +EQE T L
Sbjct: 2141 KLRKE-AEQEAARRAQAEQAALRQKQA----ADAEMEKHKKFAEQTLRQKAQVEQELTTL 2195
Query: 107 L-------QQNTQLKRFIQELSGSSPKRRRAEDK-DEGIGSPDIWEDEKAEDLRREMIEL 158
Q L +Q L + + R + +E + S + +E ++ R E
Sbjct: 2196 RLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAEN 2255
Query: 159 RQQL--DKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQ----EKL 212
R + DK+ + R + EE + + +L V AQ+ +Q + L Q EK+
Sbjct: 2256 RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKM 2315
Query: 213 EREQQQ 218
+E+ Q
Sbjct: 2316 LKEKMQ 2321
Score = 29.3 bits (64), Expect = 5.2
Identities = 38/217 (17%), Positives = 78/217 (35%), Gaps = 20/217 (9%)
Query: 18 RKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPH 77
R E E+ S A E +E ++ ERR Q A
Sbjct: 1576 RSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERA-------R 1628
Query: 78 TDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGI 137
+ E+ + L+ L+ E+ + Q + Q+ RRR + +++ +
Sbjct: 1629 EEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1688
Query: 138 GSPDIWEDEKAEDLR-------------REMIELRQQLDKERSVRMMLEEQVRSLEAHMY 184
++ E E + + +E+I LR + ++ R +LEE++ L+
Sbjct: 1689 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1748
Query: 185 PEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRT 221
K + +L + + ++ +L K E++ T
Sbjct: 1749 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRST 1785
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 48.5 bits (114), Expect = 8e-06
Identities = 58/211 (27%), Positives = 103/211 (48%), Gaps = 20/211 (9%)
Query: 15 QHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTL 74
Q FRK +E IG + + Q I+R+ ++ + R ++I A + K
Sbjct: 2404 QRFRKQAEE-IGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAI-AELEREK-- 2459
Query: 75 IPHTDGEKLSKAA-ILQQTAEYIFSLEQEKTRLLQQNTQLKR-FIQELSGSSPKRRRAED 132
EKL + A +LQ +E + +++QE+ LLQ+ L++ F+ E + R E
Sbjct: 2460 ------EKLQQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQ 2511
Query: 133 KDEGIGSPDIWEDE--KAEDLRREMIELRQQLDKERS--VRMMLEEQVRSLEAHMYPEKL 188
+ + +++DE KA+ LR E +QQ+++ER V M E + R EA +
Sbjct: 2512 EKAKL--EQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRK 2569
Query: 189 KVIAQQVQLQQQQEQVRLLHQEKLEREQQQL 219
+ QQ++ Q++Q++ L + + REQ QL
Sbjct: 2570 QEELQQLEQQRRQQEELLAEENQRLREQLQL 2600
Score = 46.6 bits (109), Expect = 3e-05
Identities = 41/197 (20%), Positives = 88/197 (44%), Gaps = 29/197 (14%)
Query: 41 QRDQERRIRREIANSNERRR--------MQSINAGFQSLKTLIPHTDGEKLSKAAILQQT 92
+R+ E R+++ +A E R ++ + A + + L + E + + Q+
Sbjct: 1983 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2042
Query: 93 AE---------YIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIW 143
A+ + F+++Q++ L Q Q + + +L G + RRA ++ E
Sbjct: 2043 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAE-------- 2094
Query: 144 EDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRS-LEAHMYPEKLKVIAQQVQLQQ-QQ 201
E RE + R+Q+++ ++ EEQ ++ +A EKL+ A+Q ++ Q
Sbjct: 2095 --EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA 2152
Query: 202 EQVRLLHQEKLEREQQQ 218
EQ L ++ + E ++
Sbjct: 2153 EQAALRQKQAADAEMEK 2169
Score = 35.0 bits (79), Expect = 0.096
Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 11/97 (11%)
Query: 126 KRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERSVRMMLE------EQVRSL 179
++++A+ + EG+G +AE +++ L + ++R LE EQVRSL
Sbjct: 1025 EQQKAQAEVEGLGKGVARLSAEAE----KVLALPEPSPAAPTLRSELELTLGKLEQVRSL 1080
Query: 180 EAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQ 216
A +Y EKLK I+ ++ Q E+V H+E+L+ Q
Sbjct: 1081 SA-IYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQ 1116
Score = 34.7 bits (78), Expect = 0.12
Identities = 48/229 (20%), Positives = 92/229 (40%), Gaps = 22/229 (9%)
Query: 9 QKVPSLQHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGF 68
Q + + RK ++ L + D E ++ A R++ Q +
Sbjct: 2130 QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQ-VEQEL 2188
Query: 69 QSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRR 128
+L+ + TD +K LQ+ ++++++ ++ ++ ++ELS R
Sbjct: 2189 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELS-KLKARI 2247
Query: 129 RAEDKDEGIGSPDIW------EDEKAEDLRREMIELRQQLDKERSVRMMLEE---QVRSL 179
AE++ + D E EK + + E L + +R + EE Q R+L
Sbjct: 2248 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2307
Query: 180 EAHMYPEKLKVIAQQVQL-------QQQ----QEQVRLLHQEKLEREQQ 217
M EK++ + + +L QQQ QEQ R L ++K + QQ
Sbjct: 2308 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQ 2356
Score = 33.1 bits (74), Expect = 0.36
Identities = 39/191 (20%), Positives = 80/191 (41%), Gaps = 22/191 (11%)
Query: 42 RDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQ 101
+++ R+RR++ + ++R+R + L + + K LQ E E+
Sbjct: 1493 QEEAERLRRQVQDESQRKRQAEV-----ELASRVKAEAEAAREKQRALQALEELRLQAEE 1547
Query: 102 EKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPD--------IWEDEKAEDLRR 153
+ RL Q + R +Q ++ + AE + + + + E+ A R
Sbjct: 1548 AERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLR 1607
Query: 154 EMIELRQQLD------KERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLL 207
E E R Q +E + R + Q+++ EA + + +AQQ L Q + + +
Sbjct: 1608 EEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQ-- 1665
Query: 208 HQEKLEREQQQ 218
+E+ ERE ++
Sbjct: 1666 -KEEAEREARR 1675
Score = 30.0 bits (66), Expect = 3.1
Identities = 43/186 (23%), Positives = 74/186 (39%), Gaps = 19/186 (10%)
Query: 47 RIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRL 106
++R+E A RR Q+ A + + D E +QT +EQE T L
Sbjct: 2137 KLRKE-AEQEAARRAQAEQAALRQKQA----ADAEMEKHKKFAEQTLRQKAQVEQELTTL 2191
Query: 107 L-------QQNTQLKRFIQELSGSSPKRRRAEDK-DEGIGSPDIWEDEKAEDLRREMIEL 158
Q L +Q L + + R + +E + S + +E ++ R E
Sbjct: 2192 RLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAEN 2251
Query: 159 RQQL--DKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQ----EKL 212
R + DK+ + R + EE + + +L V AQ+ +Q + L Q EK+
Sbjct: 2252 RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKM 2311
Query: 213 EREQQQ 218
+E+ Q
Sbjct: 2312 LKEKMQ 2317
Score = 29.3 bits (64), Expect = 5.2
Identities = 38/217 (17%), Positives = 78/217 (35%), Gaps = 20/217 (9%)
Query: 18 RKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPH 77
R E E+ S A E +E ++ ERR Q A
Sbjct: 1572 RSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERA-------R 1624
Query: 78 TDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGI 137
+ E+ + L+ L+ E+ + Q + Q+ RRR + +++ +
Sbjct: 1625 EEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1684
Query: 138 GSPDIWEDEKAEDLR-------------REMIELRQQLDKERSVRMMLEEQVRSLEAHMY 184
++ E E + + +E+I LR + ++ R +LEE++ L+
Sbjct: 1685 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1744
Query: 185 PEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRT 221
K + +L + + ++ +L K E++ T
Sbjct: 1745 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRST 1781
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 48.5 bits (114), Expect = 8e-06
Identities = 58/211 (27%), Positives = 103/211 (48%), Gaps = 20/211 (9%)
Query: 15 QHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTL 74
Q FRK +E IG + + Q I+R+ ++ + R ++I A + K
Sbjct: 2372 QRFRKQAEE-IGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAI-AELEREK-- 2427
Query: 75 IPHTDGEKLSKAA-ILQQTAEYIFSLEQEKTRLLQQNTQLKR-FIQELSGSSPKRRRAED 132
EKL + A +LQ +E + +++QE+ LLQ+ L++ F+ E + R E
Sbjct: 2428 ------EKLQQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQ 2479
Query: 133 KDEGIGSPDIWEDE--KAEDLRREMIELRQQLDKERS--VRMMLEEQVRSLEAHMYPEKL 188
+ + +++DE KA+ LR E +QQ+++ER V M E + R EA +
Sbjct: 2480 EKAKL--EQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRK 2537
Query: 189 KVIAQQVQLQQQQEQVRLLHQEKLEREQQQL 219
+ QQ++ Q++Q++ L + + REQ QL
Sbjct: 2538 QEELQQLEQQRRQQEELLAEENQRLREQLQL 2568
Score = 46.6 bits (109), Expect = 3e-05
Identities = 41/197 (20%), Positives = 88/197 (44%), Gaps = 29/197 (14%)
Query: 41 QRDQERRIRREIANSNERRR--------MQSINAGFQSLKTLIPHTDGEKLSKAAILQQT 92
+R+ E R+++ +A E R ++ + A + + L + E + + Q+
Sbjct: 1951 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2010
Query: 93 AE---------YIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIW 143
A+ + F+++Q++ L Q Q + + +L G + RRA ++ E
Sbjct: 2011 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAE-------- 2062
Query: 144 EDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRS-LEAHMYPEKLKVIAQQVQLQQ-QQ 201
E RE + R+Q+++ ++ EEQ ++ +A EKL+ A+Q ++ Q
Sbjct: 2063 --EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA 2120
Query: 202 EQVRLLHQEKLEREQQQ 218
EQ L ++ + E ++
Sbjct: 2121 EQAALRQKQAADAEMEK 2137
Score = 35.0 bits (79), Expect = 0.096
Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 11/97 (11%)
Query: 126 KRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERSVRMMLE------EQVRSL 179
++++A+ + EG+G +AE +++ L + ++R LE EQVRSL
Sbjct: 993 EQQKAQAEVEGLGKGVARLSAEAE----KVLALPEPSPAAPTLRSELELTLGKLEQVRSL 1048
Query: 180 EAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQ 216
A +Y EKLK I+ ++ Q E+V H+E+L+ Q
Sbjct: 1049 SA-IYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQ 1084
Score = 34.7 bits (78), Expect = 0.12
Identities = 48/229 (20%), Positives = 92/229 (40%), Gaps = 22/229 (9%)
Query: 9 QKVPSLQHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGF 68
Q + + RK ++ L + D E ++ A R++ Q +
Sbjct: 2098 QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQ-VEQEL 2156
Query: 69 QSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRR 128
+L+ + TD +K LQ+ ++++++ ++ ++ ++ELS R
Sbjct: 2157 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELS-KLKARI 2215
Query: 129 RAEDKDEGIGSPDIW------EDEKAEDLRREMIELRQQLDKERSVRMMLEE---QVRSL 179
AE++ + D E EK + + E L + +R + EE Q R+L
Sbjct: 2216 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2275
Query: 180 EAHMYPEKLKVIAQQVQL-------QQQ----QEQVRLLHQEKLEREQQ 217
M EK++ + + +L QQQ QEQ R L ++K + QQ
Sbjct: 2276 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQ 2324
Score = 33.1 bits (74), Expect = 0.36
Identities = 39/191 (20%), Positives = 80/191 (41%), Gaps = 22/191 (11%)
Query: 42 RDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQ 101
+++ R+RR++ + ++R+R + L + + K LQ E E+
Sbjct: 1461 QEEAERLRRQVQDESQRKRQAEV-----ELASRVKAEAEAAREKQRALQALEELRLQAEE 1515
Query: 102 EKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPD--------IWEDEKAEDLRR 153
+ RL Q + R +Q ++ + AE + + + + E+ A R
Sbjct: 1516 AERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLR 1575
Query: 154 EMIELRQQLD------KERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLL 207
E E R Q +E + R + Q+++ EA + + +AQQ L Q + + +
Sbjct: 1576 EEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQ-- 1633
Query: 208 HQEKLEREQQQ 218
+E+ ERE ++
Sbjct: 1634 -KEEAEREARR 1643
Score = 30.0 bits (66), Expect = 3.1
Identities = 43/186 (23%), Positives = 74/186 (39%), Gaps = 19/186 (10%)
Query: 47 RIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRL 106
++R+E A RR Q+ A + + D E +QT +EQE T L
Sbjct: 2105 KLRKE-AEQEAARRAQAEQAALRQKQA----ADAEMEKHKKFAEQTLRQKAQVEQELTTL 2159
Query: 107 L-------QQNTQLKRFIQELSGSSPKRRRAEDK-DEGIGSPDIWEDEKAEDLRREMIEL 158
Q L +Q L + + R + +E + S + +E ++ R E
Sbjct: 2160 RLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAEN 2219
Query: 159 RQQL--DKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQ----EKL 212
R + DK+ + R + EE + + +L V AQ+ +Q + L Q EK+
Sbjct: 2220 RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKM 2279
Query: 213 EREQQQ 218
+E+ Q
Sbjct: 2280 LKEKMQ 2285
Score = 29.3 bits (64), Expect = 5.2
Identities = 38/217 (17%), Positives = 78/217 (35%), Gaps = 20/217 (9%)
Query: 18 RKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPH 77
R E E+ S A E +E ++ ERR Q A
Sbjct: 1540 RSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERA-------R 1592
Query: 78 TDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGI 137
+ E+ + L+ L+ E+ + Q + Q+ RRR + +++ +
Sbjct: 1593 EEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1652
Query: 138 GSPDIWEDEKAEDLR-------------REMIELRQQLDKERSVRMMLEEQVRSLEAHMY 184
++ E E + + +E+I LR + ++ R +LEE++ L+
Sbjct: 1653 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1712
Query: 185 PEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRT 221
K + +L + + ++ +L K E++ T
Sbjct: 1713 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRST 1749
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 48.5 bits (114), Expect = 8e-06
Identities = 58/211 (27%), Positives = 103/211 (48%), Gaps = 20/211 (9%)
Query: 15 QHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTL 74
Q FRK +E IG + + Q I+R+ ++ + R ++I A + K
Sbjct: 2541 QRFRKQAEE-IGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAI-AELEREK-- 2596
Query: 75 IPHTDGEKLSKAA-ILQQTAEYIFSLEQEKTRLLQQNTQLKR-FIQELSGSSPKRRRAED 132
EKL + A +LQ +E + +++QE+ LLQ+ L++ F+ E + R E
Sbjct: 2597 ------EKLQQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQ 2648
Query: 133 KDEGIGSPDIWEDE--KAEDLRREMIELRQQLDKERS--VRMMLEEQVRSLEAHMYPEKL 188
+ + +++DE KA+ LR E +QQ+++ER V M E + R EA +
Sbjct: 2649 EKAKL--EQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRK 2706
Query: 189 KVIAQQVQLQQQQEQVRLLHQEKLEREQQQL 219
+ QQ++ Q++Q++ L + + REQ QL
Sbjct: 2707 QEELQQLEQQRRQQEELLAEENQRLREQLQL 2737
Score = 46.6 bits (109), Expect = 3e-05
Identities = 41/197 (20%), Positives = 88/197 (44%), Gaps = 29/197 (14%)
Query: 41 QRDQERRIRREIANSNERRR--------MQSINAGFQSLKTLIPHTDGEKLSKAAILQQT 92
+R+ E R+++ +A E R ++ + A + + L + E + + Q+
Sbjct: 2120 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2179
Query: 93 AE---------YIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIW 143
A+ + F+++Q++ L Q Q + + +L G + RRA ++ E
Sbjct: 2180 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAE-------- 2231
Query: 144 EDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRS-LEAHMYPEKLKVIAQQVQLQQ-QQ 201
E RE + R+Q+++ ++ EEQ ++ +A EKL+ A+Q ++ Q
Sbjct: 2232 --EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA 2289
Query: 202 EQVRLLHQEKLEREQQQ 218
EQ L ++ + E ++
Sbjct: 2290 EQAALRQKQAADAEMEK 2306
Score = 35.0 bits (79), Expect = 0.096
Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 11/97 (11%)
Query: 126 KRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERSVRMMLE------EQVRSL 179
++++A+ + EG+G +AE +++ L + ++R LE EQVRSL
Sbjct: 1162 EQQKAQAEVEGLGKGVARLSAEAE----KVLALPEPSPAAPTLRSELELTLGKLEQVRSL 1217
Query: 180 EAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQ 216
A +Y EKLK I+ ++ Q E+V H+E+L+ Q
Sbjct: 1218 SA-IYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQ 1253
Score = 34.7 bits (78), Expect = 0.12
Identities = 48/229 (20%), Positives = 92/229 (40%), Gaps = 22/229 (9%)
Query: 9 QKVPSLQHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGF 68
Q + + RK ++ L + D E ++ A R++ Q +
Sbjct: 2267 QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQ-VEQEL 2325
Query: 69 QSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRR 128
+L+ + TD +K LQ+ ++++++ ++ ++ ++ELS R
Sbjct: 2326 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELS-KLKARI 2384
Query: 129 RAEDKDEGIGSPDIW------EDEKAEDLRREMIELRQQLDKERSVRMMLEE---QVRSL 179
AE++ + D E EK + + E L + +R + EE Q R+L
Sbjct: 2385 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2444
Query: 180 EAHMYPEKLKVIAQQVQL-------QQQ----QEQVRLLHQEKLEREQQ 217
M EK++ + + +L QQQ QEQ R L ++K + QQ
Sbjct: 2445 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQ 2493
Score = 33.1 bits (74), Expect = 0.36
Identities = 39/191 (20%), Positives = 80/191 (41%), Gaps = 22/191 (11%)
Query: 42 RDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQ 101
+++ R+RR++ + ++R+R + L + + K LQ E E+
Sbjct: 1630 QEEAERLRRQVQDESQRKRQAEV-----ELASRVKAEAEAAREKQRALQALEELRLQAEE 1684
Query: 102 EKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPD--------IWEDEKAEDLRR 153
+ RL Q + R +Q ++ + AE + + + + E+ A R
Sbjct: 1685 AERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLR 1744
Query: 154 EMIELRQQLD------KERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLL 207
E E R Q +E + R + Q+++ EA + + +AQQ L Q + + +
Sbjct: 1745 EEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQ-- 1802
Query: 208 HQEKLEREQQQ 218
+E+ ERE ++
Sbjct: 1803 -KEEAEREARR 1812
Score = 30.0 bits (66), Expect = 3.1
Identities = 43/186 (23%), Positives = 74/186 (39%), Gaps = 19/186 (10%)
Query: 47 RIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRL 106
++R+E A RR Q+ A + + D E +QT +EQE T L
Sbjct: 2274 KLRKE-AEQEAARRAQAEQAALRQKQA----ADAEMEKHKKFAEQTLRQKAQVEQELTTL 2328
Query: 107 L-------QQNTQLKRFIQELSGSSPKRRRAEDK-DEGIGSPDIWEDEKAEDLRREMIEL 158
Q L +Q L + + R + +E + S + +E ++ R E
Sbjct: 2329 RLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAEN 2388
Query: 159 RQQL--DKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQ----EKL 212
R + DK+ + R + EE + + +L V AQ+ +Q + L Q EK+
Sbjct: 2389 RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKM 2448
Query: 213 EREQQQ 218
+E+ Q
Sbjct: 2449 LKEKMQ 2454
Score = 29.3 bits (64), Expect = 5.2
Identities = 38/217 (17%), Positives = 78/217 (35%), Gaps = 20/217 (9%)
Query: 18 RKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPH 77
R E E+ S A E +E ++ ERR Q A
Sbjct: 1709 RSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERA-------R 1761
Query: 78 TDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGI 137
+ E+ + L+ L+ E+ + Q + Q+ RRR + +++ +
Sbjct: 1762 EEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1821
Query: 138 GSPDIWEDEKAEDLR-------------REMIELRQQLDKERSVRMMLEEQVRSLEAHMY 184
++ E E + + +E+I LR + ++ R +LEE++ L+
Sbjct: 1822 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1881
Query: 185 PEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRT 221
K + +L + + ++ +L K E++ T
Sbjct: 1882 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRST 1918
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 48.5 bits (114), Expect = 8e-06
Identities = 58/211 (27%), Positives = 103/211 (48%), Gaps = 20/211 (9%)
Query: 15 QHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTL 74
Q FRK +E IG + + Q I+R+ ++ + R ++I A + K
Sbjct: 2382 QRFRKQAEE-IGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAI-AELEREK-- 2437
Query: 75 IPHTDGEKLSKAA-ILQQTAEYIFSLEQEKTRLLQQNTQLKR-FIQELSGSSPKRRRAED 132
EKL + A +LQ +E + +++QE+ LLQ+ L++ F+ E + R E
Sbjct: 2438 ------EKLQQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQ 2489
Query: 133 KDEGIGSPDIWEDE--KAEDLRREMIELRQQLDKERS--VRMMLEEQVRSLEAHMYPEKL 188
+ + +++DE KA+ LR E +QQ+++ER V M E + R EA +
Sbjct: 2490 EKAKL--EQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRK 2547
Query: 189 KVIAQQVQLQQQQEQVRLLHQEKLEREQQQL 219
+ QQ++ Q++Q++ L + + REQ QL
Sbjct: 2548 QEELQQLEQQRRQQEELLAEENQRLREQLQL 2578
Score = 46.6 bits (109), Expect = 3e-05
Identities = 41/197 (20%), Positives = 88/197 (44%), Gaps = 29/197 (14%)
Query: 41 QRDQERRIRREIANSNERRR--------MQSINAGFQSLKTLIPHTDGEKLSKAAILQQT 92
+R+ E R+++ +A E R ++ + A + + L + E + + Q+
Sbjct: 1961 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2020
Query: 93 AE---------YIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIW 143
A+ + F+++Q++ L Q Q + + +L G + RRA ++ E
Sbjct: 2021 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAE-------- 2072
Query: 144 EDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRS-LEAHMYPEKLKVIAQQVQLQQ-QQ 201
E RE + R+Q+++ ++ EEQ ++ +A EKL+ A+Q ++ Q
Sbjct: 2073 --EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA 2130
Query: 202 EQVRLLHQEKLEREQQQ 218
EQ L ++ + E ++
Sbjct: 2131 EQAALRQKQAADAEMEK 2147
Score = 35.0 bits (79), Expect = 0.096
Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 11/97 (11%)
Query: 126 KRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERSVRMMLE------EQVRSL 179
++++A+ + EG+G +AE +++ L + ++R LE EQVRSL
Sbjct: 1003 EQQKAQAEVEGLGKGVARLSAEAE----KVLALPEPSPAAPTLRSELELTLGKLEQVRSL 1058
Query: 180 EAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQ 216
A +Y EKLK I+ ++ Q E+V H+E+L+ Q
Sbjct: 1059 SA-IYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQ 1094
Score = 34.7 bits (78), Expect = 0.12
Identities = 48/229 (20%), Positives = 92/229 (40%), Gaps = 22/229 (9%)
Query: 9 QKVPSLQHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGF 68
Q + + RK ++ L + D E ++ A R++ Q +
Sbjct: 2108 QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQ-VEQEL 2166
Query: 69 QSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRR 128
+L+ + TD +K LQ+ ++++++ ++ ++ ++ELS R
Sbjct: 2167 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELS-KLKARI 2225
Query: 129 RAEDKDEGIGSPDIW------EDEKAEDLRREMIELRQQLDKERSVRMMLEE---QVRSL 179
AE++ + D E EK + + E L + +R + EE Q R+L
Sbjct: 2226 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2285
Query: 180 EAHMYPEKLKVIAQQVQL-------QQQ----QEQVRLLHQEKLEREQQ 217
M EK++ + + +L QQQ QEQ R L ++K + QQ
Sbjct: 2286 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQ 2334
Score = 33.1 bits (74), Expect = 0.36
Identities = 39/191 (20%), Positives = 80/191 (41%), Gaps = 22/191 (11%)
Query: 42 RDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQ 101
+++ R+RR++ + ++R+R + L + + K LQ E E+
Sbjct: 1471 QEEAERLRRQVQDESQRKRQAEV-----ELASRVKAEAEAAREKQRALQALEELRLQAEE 1525
Query: 102 EKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPD--------IWEDEKAEDLRR 153
+ RL Q + R +Q ++ + AE + + + + E+ A R
Sbjct: 1526 AERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLR 1585
Query: 154 EMIELRQQLD------KERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLL 207
E E R Q +E + R + Q+++ EA + + +AQQ L Q + + +
Sbjct: 1586 EEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQ-- 1643
Query: 208 HQEKLEREQQQ 218
+E+ ERE ++
Sbjct: 1644 -KEEAEREARR 1653
Score = 30.0 bits (66), Expect = 3.1
Identities = 43/186 (23%), Positives = 74/186 (39%), Gaps = 19/186 (10%)
Query: 47 RIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRL 106
++R+E A RR Q+ A + + D E +QT +EQE T L
Sbjct: 2115 KLRKE-AEQEAARRAQAEQAALRQKQA----ADAEMEKHKKFAEQTLRQKAQVEQELTTL 2169
Query: 107 L-------QQNTQLKRFIQELSGSSPKRRRAEDK-DEGIGSPDIWEDEKAEDLRREMIEL 158
Q L +Q L + + R + +E + S + +E ++ R E
Sbjct: 2170 RLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAEN 2229
Query: 159 RQQL--DKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQ----EKL 212
R + DK+ + R + EE + + +L V AQ+ +Q + L Q EK+
Sbjct: 2230 RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKM 2289
Query: 213 EREQQQ 218
+E+ Q
Sbjct: 2290 LKEKMQ 2295
Score = 29.3 bits (64), Expect = 5.2
Identities = 38/217 (17%), Positives = 78/217 (35%), Gaps = 20/217 (9%)
Query: 18 RKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPH 77
R E E+ S A E +E ++ ERR Q A
Sbjct: 1550 RSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERA-------R 1602
Query: 78 TDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGI 137
+ E+ + L+ L+ E+ + Q + Q+ RRR + +++ +
Sbjct: 1603 EEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1662
Query: 138 GSPDIWEDEKAEDLR-------------REMIELRQQLDKERSVRMMLEEQVRSLEAHMY 184
++ E E + + +E+I LR + ++ R +LEE++ L+
Sbjct: 1663 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1722
Query: 185 PEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRT 221
K + +L + + ++ +L K E++ T
Sbjct: 1723 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRST 1759
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 48.5 bits (114), Expect = 8e-06
Identities = 58/211 (27%), Positives = 103/211 (48%), Gaps = 20/211 (9%)
Query: 15 QHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTL 74
Q FRK +E IG + + Q I+R+ ++ + R ++I A + K
Sbjct: 2390 QRFRKQAEE-IGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAI-AELEREK-- 2445
Query: 75 IPHTDGEKLSKAA-ILQQTAEYIFSLEQEKTRLLQQNTQLKR-FIQELSGSSPKRRRAED 132
EKL + A +LQ +E + +++QE+ LLQ+ L++ F+ E + R E
Sbjct: 2446 ------EKLQQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQ 2497
Query: 133 KDEGIGSPDIWEDE--KAEDLRREMIELRQQLDKERS--VRMMLEEQVRSLEAHMYPEKL 188
+ + +++DE KA+ LR E +QQ+++ER V M E + R EA +
Sbjct: 2498 EKAKL--EQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRK 2555
Query: 189 KVIAQQVQLQQQQEQVRLLHQEKLEREQQQL 219
+ QQ++ Q++Q++ L + + REQ QL
Sbjct: 2556 QEELQQLEQQRRQQEELLAEENQRLREQLQL 2586
Score = 46.6 bits (109), Expect = 3e-05
Identities = 41/197 (20%), Positives = 88/197 (44%), Gaps = 29/197 (14%)
Query: 41 QRDQERRIRREIANSNERRR--------MQSINAGFQSLKTLIPHTDGEKLSKAAILQQT 92
+R+ E R+++ +A E R ++ + A + + L + E + + Q+
Sbjct: 1969 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2028
Query: 93 AE---------YIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIW 143
A+ + F+++Q++ L Q Q + + +L G + RRA ++ E
Sbjct: 2029 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAE-------- 2080
Query: 144 EDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRS-LEAHMYPEKLKVIAQQVQLQQ-QQ 201
E RE + R+Q+++ ++ EEQ ++ +A EKL+ A+Q ++ Q
Sbjct: 2081 --EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA 2138
Query: 202 EQVRLLHQEKLEREQQQ 218
EQ L ++ + E ++
Sbjct: 2139 EQAALRQKQAADAEMEK 2155
Score = 35.0 bits (79), Expect = 0.096
Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 11/97 (11%)
Query: 126 KRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERSVRMMLE------EQVRSL 179
++++A+ + EG+G +AE +++ L + ++R LE EQVRSL
Sbjct: 1011 EQQKAQAEVEGLGKGVARLSAEAE----KVLALPEPSPAAPTLRSELELTLGKLEQVRSL 1066
Query: 180 EAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQ 216
A +Y EKLK I+ ++ Q E+V H+E+L+ Q
Sbjct: 1067 SA-IYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQ 1102
Score = 34.7 bits (78), Expect = 0.12
Identities = 48/229 (20%), Positives = 92/229 (40%), Gaps = 22/229 (9%)
Query: 9 QKVPSLQHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGF 68
Q + + RK ++ L + D E ++ A R++ Q +
Sbjct: 2116 QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQ-VEQEL 2174
Query: 69 QSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRR 128
+L+ + TD +K LQ+ ++++++ ++ ++ ++ELS R
Sbjct: 2175 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELS-KLKARI 2233
Query: 129 RAEDKDEGIGSPDIW------EDEKAEDLRREMIELRQQLDKERSVRMMLEE---QVRSL 179
AE++ + D E EK + + E L + +R + EE Q R+L
Sbjct: 2234 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2293
Query: 180 EAHMYPEKLKVIAQQVQL-------QQQ----QEQVRLLHQEKLEREQQ 217
M EK++ + + +L QQQ QEQ R L ++K + QQ
Sbjct: 2294 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQ 2342
Score = 33.1 bits (74), Expect = 0.36
Identities = 39/191 (20%), Positives = 80/191 (41%), Gaps = 22/191 (11%)
Query: 42 RDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQ 101
+++ R+RR++ + ++R+R + L + + K LQ E E+
Sbjct: 1479 QEEAERLRRQVQDESQRKRQAEV-----ELASRVKAEAEAAREKQRALQALEELRLQAEE 1533
Query: 102 EKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPD--------IWEDEKAEDLRR 153
+ RL Q + R +Q ++ + AE + + + + E+ A R
Sbjct: 1534 AERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLR 1593
Query: 154 EMIELRQQLD------KERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLL 207
E E R Q +E + R + Q+++ EA + + +AQQ L Q + + +
Sbjct: 1594 EEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQ-- 1651
Query: 208 HQEKLEREQQQ 218
+E+ ERE ++
Sbjct: 1652 -KEEAEREARR 1661
Score = 30.0 bits (66), Expect = 3.1
Identities = 43/186 (23%), Positives = 74/186 (39%), Gaps = 19/186 (10%)
Query: 47 RIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRL 106
++R+E A RR Q+ A + + D E +QT +EQE T L
Sbjct: 2123 KLRKE-AEQEAARRAQAEQAALRQKQA----ADAEMEKHKKFAEQTLRQKAQVEQELTTL 2177
Query: 107 L-------QQNTQLKRFIQELSGSSPKRRRAEDK-DEGIGSPDIWEDEKAEDLRREMIEL 158
Q L +Q L + + R + +E + S + +E ++ R E
Sbjct: 2178 RLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAEN 2237
Query: 159 RQQL--DKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQ----EKL 212
R + DK+ + R + EE + + +L V AQ+ +Q + L Q EK+
Sbjct: 2238 RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKM 2297
Query: 213 EREQQQ 218
+E+ Q
Sbjct: 2298 LKEKMQ 2303
Score = 29.3 bits (64), Expect = 5.2
Identities = 38/217 (17%), Positives = 78/217 (35%), Gaps = 20/217 (9%)
Query: 18 RKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPH 77
R E E+ S A E +E ++ ERR Q A
Sbjct: 1558 RSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERA-------R 1610
Query: 78 TDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGI 137
+ E+ + L+ L+ E+ + Q + Q+ RRR + +++ +
Sbjct: 1611 EEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1670
Query: 138 GSPDIWEDEKAEDLR-------------REMIELRQQLDKERSVRMMLEEQVRSLEAHMY 184
++ E E + + +E+I LR + ++ R +LEE++ L+
Sbjct: 1671 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1730
Query: 185 PEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRT 221
K + +L + + ++ +L K E++ T
Sbjct: 1731 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRST 1767
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 48.5 bits (114), Expect = 8e-06
Identities = 58/211 (27%), Positives = 103/211 (48%), Gaps = 20/211 (9%)
Query: 15 QHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTL 74
Q FRK +E IG + + Q I+R+ ++ + R ++I A + K
Sbjct: 2431 QRFRKQAEE-IGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAI-AELEREK-- 2486
Query: 75 IPHTDGEKLSKAA-ILQQTAEYIFSLEQEKTRLLQQNTQLKR-FIQELSGSSPKRRRAED 132
EKL + A +LQ +E + +++QE+ LLQ+ L++ F+ E + R E
Sbjct: 2487 ------EKLQQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQ 2538
Query: 133 KDEGIGSPDIWEDE--KAEDLRREMIELRQQLDKERS--VRMMLEEQVRSLEAHMYPEKL 188
+ + +++DE KA+ LR E +QQ+++ER V M E + R EA +
Sbjct: 2539 EKAKL--EQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRK 2596
Query: 189 KVIAQQVQLQQQQEQVRLLHQEKLEREQQQL 219
+ QQ++ Q++Q++ L + + REQ QL
Sbjct: 2597 QEELQQLEQQRRQQEELLAEENQRLREQLQL 2627
Score = 46.6 bits (109), Expect = 3e-05
Identities = 41/197 (20%), Positives = 88/197 (44%), Gaps = 29/197 (14%)
Query: 41 QRDQERRIRREIANSNERRR--------MQSINAGFQSLKTLIPHTDGEKLSKAAILQQT 92
+R+ E R+++ +A E R ++ + A + + L + E + + Q+
Sbjct: 2010 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2069
Query: 93 AE---------YIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIW 143
A+ + F+++Q++ L Q Q + + +L G + RRA ++ E
Sbjct: 2070 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAE-------- 2121
Query: 144 EDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRS-LEAHMYPEKLKVIAQQVQLQQ-QQ 201
E RE + R+Q+++ ++ EEQ ++ +A EKL+ A+Q ++ Q
Sbjct: 2122 --EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA 2179
Query: 202 EQVRLLHQEKLEREQQQ 218
EQ L ++ + E ++
Sbjct: 2180 EQAALRQKQAADAEMEK 2196
Score = 35.0 bits (79), Expect = 0.096
Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 11/97 (11%)
Query: 126 KRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERSVRMMLE------EQVRSL 179
++++A+ + EG+G +AE +++ L + ++R LE EQVRSL
Sbjct: 1052 EQQKAQAEVEGLGKGVARLSAEAE----KVLALPEPSPAAPTLRSELELTLGKLEQVRSL 1107
Query: 180 EAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQ 216
A +Y EKLK I+ ++ Q E+V H+E+L+ Q
Sbjct: 1108 SA-IYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQ 1143
Score = 34.7 bits (78), Expect = 0.12
Identities = 48/229 (20%), Positives = 92/229 (40%), Gaps = 22/229 (9%)
Query: 9 QKVPSLQHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGF 68
Q + + RK ++ L + D E ++ A R++ Q +
Sbjct: 2157 QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQ-VEQEL 2215
Query: 69 QSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRR 128
+L+ + TD +K LQ+ ++++++ ++ ++ ++ELS R
Sbjct: 2216 TTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELS-KLKARI 2274
Query: 129 RAEDKDEGIGSPDIW------EDEKAEDLRREMIELRQQLDKERSVRMMLEE---QVRSL 179
AE++ + D E EK + + E L + +R + EE Q R+L
Sbjct: 2275 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2334
Query: 180 EAHMYPEKLKVIAQQVQL-------QQQ----QEQVRLLHQEKLEREQQ 217
M EK++ + + +L QQQ QEQ R L ++K + QQ
Sbjct: 2335 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQ 2383
Score = 33.1 bits (74), Expect = 0.36
Identities = 39/191 (20%), Positives = 80/191 (41%), Gaps = 22/191 (11%)
Query: 42 RDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQ 101
+++ R+RR++ + ++R+R + L + + K LQ E E+
Sbjct: 1520 QEEAERLRRQVQDESQRKRQAEV-----ELASRVKAEAEAAREKQRALQALEELRLQAEE 1574
Query: 102 EKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPD--------IWEDEKAEDLRR 153
+ RL Q + R +Q ++ + AE + + + + E+ A R
Sbjct: 1575 AERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLR 1634
Query: 154 EMIELRQQLD------KERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLL 207
E E R Q +E + R + Q+++ EA + + +AQQ L Q + + +
Sbjct: 1635 EEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQ-- 1692
Query: 208 HQEKLEREQQQ 218
+E+ ERE ++
Sbjct: 1693 -KEEAEREARR 1702
Score = 30.0 bits (66), Expect = 3.1
Identities = 43/186 (23%), Positives = 74/186 (39%), Gaps = 19/186 (10%)
Query: 47 RIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRL 106
++R+E A RR Q+ A + + D E +QT +EQE T L
Sbjct: 2164 KLRKE-AEQEAARRAQAEQAALRQKQA----ADAEMEKHKKFAEQTLRQKAQVEQELTTL 2218
Query: 107 L-------QQNTQLKRFIQELSGSSPKRRRAEDK-DEGIGSPDIWEDEKAEDLRREMIEL 158
Q L +Q L + + R + +E + S + +E ++ R E
Sbjct: 2219 RLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAEN 2278
Query: 159 RQQL--DKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQ----EKL 212
R + DK+ + R + EE + + +L V AQ+ +Q + L Q EK+
Sbjct: 2279 RALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKM 2338
Query: 213 EREQQQ 218
+E+ Q
Sbjct: 2339 LKEKMQ 2344
Score = 29.3 bits (64), Expect = 5.2
Identities = 38/217 (17%), Positives = 78/217 (35%), Gaps = 20/217 (9%)
Query: 18 RKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPH 77
R E E+ S A E +E ++ ERR Q A
Sbjct: 1599 RSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERA-------R 1651
Query: 78 TDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGI 137
+ E+ + L+ L+ E+ + Q + Q+ RRR + +++ +
Sbjct: 1652 EEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1711
Query: 138 GSPDIWEDEKAEDLR-------------REMIELRQQLDKERSVRMMLEEQVRSLEAHMY 184
++ E E + + +E+I LR + ++ R +LEE++ L+
Sbjct: 1712 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1771
Query: 185 PEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRT 221
K + +L + + ++ +L K E++ T
Sbjct: 1772 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRST 1808
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 47.4 bits (111), Expect = 2e-05
Identities = 61/259 (23%), Positives = 113/259 (43%), Gaps = 55/259 (21%)
Query: 39 ETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFS 98
E +R QE +RR+ +RR + + + + A+ +Q + I
Sbjct: 754 ELRRQQEEILRRQQEEERKRREEEEL---------------ARRKQEEALRRQREQEIAL 798
Query: 99 LEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAED---KDEGIGSPDIWEDEKAEDLRREM 155
Q + QQ + R ++E +RR+ E+ K E + E+E+A+ R +
Sbjct: 799 RRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQ---RRL 855
Query: 156 IELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLERE 215
E R ++++E + R+ EE+ R + +L+V Q+ ++Q+Q+Q L + + +++
Sbjct: 856 EENRLRMEEE-AARLRHEEEERKRK------ELEVQRQKELMRQRQQQQEALRRLQQQQQ 908
Query: 216 QQQLRTQLLPPPAPTHHPTVIVPAPPPPPSHHINVVTMGPSSVINSVSTSRQNLDTIVQA 275
QQQL LP + T G S N+ + Q ++ +
Sbjct: 909 QQQLAQMKLPSSS-----------------------TWGQQS--NTTACQSQATLSLAE- 942
Query: 276 IQHIEGTQEKQELEEEQRR 294
IQ +E +E+Q L EEQRR
Sbjct: 943 IQKLEEERERQ-LREEQRR 960
Score = 38.1 bits (87), Expect = 0.011
Identities = 27/87 (31%), Positives = 50/87 (57%), Gaps = 6/87 (6%)
Query: 144 EDEKAEDLRREMIE-LRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIA-----QQVQL 197
E ++ E+LRR+ E LR+Q ++ER R E R E + ++ + IA ++ +
Sbjct: 748 ERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEER 807
Query: 198 QQQQEQVRLLHQEKLEREQQQLRTQLL 224
QQQ+E +R L + + E E+++ + +LL
Sbjct: 808 QQQEEALRRLEERRREEEERRKQEELL 834
Score = 37.7 bits (86), Expect = 0.015
Identities = 39/146 (26%), Positives = 65/146 (44%), Gaps = 19/146 (13%)
Query: 90 QQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEG--------IGSPD 141
QQ A +Q+ LLQQ LK I + + R D G P
Sbjct: 637 QQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPT 696
Query: 142 IWEDEKAEDLRREM------IELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQV 195
+WE DL + +E QQL+K ++ + LE++ R E E+ + +Q
Sbjct: 697 VWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAK--LEQERREAEMRAKREE-EERKRQE 753
Query: 196 QLQQQQEQV--RLLHQEKLEREQQQL 219
+L++QQE++ R +E+ RE+++L
Sbjct: 754 ELRRQQEEILRRQQEEERKRREEEEL 779
Score = 31.6 bits (70), Expect = 1.1
Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 6/73 (8%)
Query: 146 EKAEDLRREMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVR 205
++ E+ R+ ELR+Q +E +R EE+ + E E+L Q+ L++Q+EQ
Sbjct: 743 KREEEERKRQEELRRQ--QEEILRRQQEEERKRREE----EELARRKQEEALRRQREQEI 796
Query: 206 LLHQEKLEREQQQ 218
L +++ E E+QQ
Sbjct: 797 ALRRQREEEERQQ 809
Score = 31.6 bits (70), Expect = 1.1
Identities = 51/265 (19%), Positives = 97/265 (36%), Gaps = 64/265 (24%)
Query: 36 LTPETQRDQERRIRREIANSNE-------------RRRMQSINAGFQSLKTLIPHTDGEK 82
L + ++ERR + E+ E +RR++ + + H + E+
Sbjct: 817 LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEER 876
Query: 83 LSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDI 142
K +Q+ E L++Q Q + ++ L +++ A+ K + S
Sbjct: 877 KRKELEVQRQKE-----------LMRQRQQQQEALRRLQQQQQQQQLAQMK---LPSSST 922
Query: 143 WEDEKAEDLRREMIELR----QQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQ 198
W + + L Q+L++ER E Q+R + E +K + QQ Q Q
Sbjct: 923 WGQQSNTTACQSQATLSLAEIQKLEEER------ERQLREEQRRQQRELMKALQQQQQQQ 976
Query: 199 QQ---------------QEQVRLLHQEKLEREQQQLRTQLLPPPAPTHHPTVIVPAPPPP 243
QQ + + + +E + ++QQ + Q P + T
Sbjct: 977 QQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNT--------- 1027
Query: 244 PSHHINVVTMGPSSVINSVSTSRQN 268
H N+ T +SV S++T N
Sbjct: 1028 ---HSNLHTSIGNSVWGSINTGPPN 1049
Score = 29.6 bits (65), Expect = 4.0
Identities = 32/158 (20%), Positives = 62/158 (39%), Gaps = 8/158 (5%)
Query: 134 DEGIGSPDIWEDEKAEDLRREMIELRQQLDK--ERSVRMMLEEQVRSLEAHMYPEKLKVI 191
+E PD ++ E R +E ++ + S R +S EA + K +
Sbjct: 336 NEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPK 395
Query: 192 AQQVQLQQQQEQVRLLHQEKLEREQQQLRTQLLPP----PAPTHHPTVIVPAPPPPPSHH 247
+Q + +++ ++ K+ ++ + P P+ T P +I+P P P PS
Sbjct: 396 TEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPT 455
Query: 248 INVVTMGPSSVINSVSTSRQNLDTIVQAIQHIEGTQEK 285
+ V S S + D + ++H+E EK
Sbjct: 456 LRPVETPVVGAPGMGSVSTEPDDE--EGLKHLEQQAEK 491
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 47.4 bits (111), Expect = 2e-05
Identities = 61/259 (23%), Positives = 113/259 (43%), Gaps = 55/259 (21%)
Query: 39 ETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFS 98
E +R QE +RR+ +RR + + + + A+ +Q + I
Sbjct: 781 ELRRQQEEILRRQQEEERKRREEEEL---------------ARRKQEEALRRQREQEIAL 825
Query: 99 LEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAED---KDEGIGSPDIWEDEKAEDLRREM 155
Q + QQ + R ++E +RR+ E+ K E + E+E+A+ R +
Sbjct: 826 RRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQ---RRL 882
Query: 156 IELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLERE 215
E R ++++E + R+ EE+ R + +L+V Q+ ++Q+Q+Q L + + +++
Sbjct: 883 EENRLRMEEE-AARLRHEEEERKRK------ELEVQRQKELMRQRQQQQEALRRLQQQQQ 935
Query: 216 QQQLRTQLLPPPAPTHHPTVIVPAPPPPPSHHINVVTMGPSSVINSVSTSRQNLDTIVQA 275
QQQL LP + T G S N+ + Q ++ +
Sbjct: 936 QQQLAQMKLPSSS-----------------------TWGQQS--NTTACQSQATLSLAE- 969
Query: 276 IQHIEGTQEKQELEEEQRR 294
IQ +E +E+Q L EEQRR
Sbjct: 970 IQKLEEERERQ-LREEQRR 987
Score = 38.1 bits (87), Expect = 0.011
Identities = 27/87 (31%), Positives = 50/87 (57%), Gaps = 6/87 (6%)
Query: 144 EDEKAEDLRREMIE-LRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIA-----QQVQL 197
E ++ E+LRR+ E LR+Q ++ER R E R E + ++ + IA ++ +
Sbjct: 775 ERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEER 834
Query: 198 QQQQEQVRLLHQEKLEREQQQLRTQLL 224
QQQ+E +R L + + E E+++ + +LL
Sbjct: 835 QQQEEALRRLEERRREEEERRKQEELL 861
Score = 37.7 bits (86), Expect = 0.015
Identities = 39/146 (26%), Positives = 65/146 (44%), Gaps = 19/146 (13%)
Query: 90 QQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEG--------IGSPD 141
QQ A +Q+ LLQQ LK I + + R D G P
Sbjct: 664 QQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPT 723
Query: 142 IWEDEKAEDLRREM------IELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQV 195
+WE DL + +E QQL+K ++ + LE++ R E E+ + +Q
Sbjct: 724 VWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAK--LEQERREAEMRAKREE-EERKRQE 780
Query: 196 QLQQQQEQV--RLLHQEKLEREQQQL 219
+L++QQE++ R +E+ RE+++L
Sbjct: 781 ELRRQQEEILRRQQEEERKRREEEEL 806
Score = 31.6 bits (70), Expect = 1.1
Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 6/73 (8%)
Query: 146 EKAEDLRREMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVR 205
++ E+ R+ ELR+Q +E +R EE+ + E E+L Q+ L++Q+EQ
Sbjct: 770 KREEEERKRQEELRRQ--QEEILRRQQEEERKRREE----EELARRKQEEALRRQREQEI 823
Query: 206 LLHQEKLEREQQQ 218
L +++ E E+QQ
Sbjct: 824 ALRRQREEEERQQ 836
Score = 31.6 bits (70), Expect = 1.1
Identities = 51/265 (19%), Positives = 97/265 (36%), Gaps = 64/265 (24%)
Query: 36 LTPETQRDQERRIRREIANSNE-------------RRRMQSINAGFQSLKTLIPHTDGEK 82
L + ++ERR + E+ E +RR++ + + H + E+
Sbjct: 844 LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEER 903
Query: 83 LSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDI 142
K +Q+ E L++Q Q + ++ L +++ A+ K + S
Sbjct: 904 KRKELEVQRQKE-----------LMRQRQQQQEALRRLQQQQQQQQLAQMK---LPSSST 949
Query: 143 WEDEKAEDLRREMIELR----QQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQ 198
W + + L Q+L++ER E Q+R + E +K + QQ Q Q
Sbjct: 950 WGQQSNTTACQSQATLSLAEIQKLEEER------ERQLREEQRRQQRELMKALQQQQQQQ 1003
Query: 199 QQ---------------QEQVRLLHQEKLEREQQQLRTQLLPPPAPTHHPTVIVPAPPPP 243
QQ + + + +E + ++QQ + Q P + T
Sbjct: 1004 QQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNT--------- 1054
Query: 244 PSHHINVVTMGPSSVINSVSTSRQN 268
H N+ T +SV S++T N
Sbjct: 1055 ---HSNLHTSIGNSVWGSINTGPPN 1076
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 47.4 bits (111), Expect = 2e-05
Identities = 61/259 (23%), Positives = 113/259 (43%), Gaps = 55/259 (21%)
Query: 39 ETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFS 98
E +R QE +RR+ +RR + + + + A+ +Q + I
Sbjct: 760 ELRRQQEEILRRQQEEERKRREEEEL---------------ARRKQEEALRRQREQEIAL 804
Query: 99 LEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAED---KDEGIGSPDIWEDEKAEDLRREM 155
Q + QQ + R ++E +RR+ E+ K E + E+E+A+ R +
Sbjct: 805 RRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQ---RRL 861
Query: 156 IELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLERE 215
E R ++++E + R+ EE+ R + +L+V Q+ ++Q+Q+Q L + + +++
Sbjct: 862 EENRLRMEEE-AARLRHEEEERKRK------ELEVQRQKELMRQRQQQQEALRRLQQQQQ 914
Query: 216 QQQLRTQLLPPPAPTHHPTVIVPAPPPPPSHHINVVTMGPSSVINSVSTSRQNLDTIVQA 275
QQQL LP + T G S N+ + Q ++ +
Sbjct: 915 QQQLAQMKLPSSS-----------------------TWGQQS--NTTACQSQATLSLAE- 948
Query: 276 IQHIEGTQEKQELEEEQRR 294
IQ +E +E+Q L EEQRR
Sbjct: 949 IQKLEEERERQ-LREEQRR 966
Score = 38.1 bits (87), Expect = 0.011
Identities = 27/87 (31%), Positives = 50/87 (57%), Gaps = 6/87 (6%)
Query: 144 EDEKAEDLRREMIE-LRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIA-----QQVQL 197
E ++ E+LRR+ E LR+Q ++ER R E R E + ++ + IA ++ +
Sbjct: 754 ERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEER 813
Query: 198 QQQQEQVRLLHQEKLEREQQQLRTQLL 224
QQQ+E +R L + + E E+++ + +LL
Sbjct: 814 QQQEEALRRLEERRREEEERRKQEELL 840
Score = 37.7 bits (86), Expect = 0.015
Identities = 39/146 (26%), Positives = 65/146 (44%), Gaps = 19/146 (13%)
Query: 90 QQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEG--------IGSPD 141
QQ A +Q+ LLQQ LK I + + R D G P
Sbjct: 643 QQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPT 702
Query: 142 IWEDEKAEDLRREM------IELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQV 195
+WE DL + +E QQL+K ++ + LE++ R E E+ + +Q
Sbjct: 703 VWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAK--LEQERREAEMRAKREE-EERKRQE 759
Query: 196 QLQQQQEQV--RLLHQEKLEREQQQL 219
+L++QQE++ R +E+ RE+++L
Sbjct: 760 ELRRQQEEILRRQQEEERKRREEEEL 785
Score = 31.6 bits (70), Expect = 1.1
Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 6/73 (8%)
Query: 146 EKAEDLRREMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVR 205
++ E+ R+ ELR+Q +E +R EE+ + E E+L Q+ L++Q+EQ
Sbjct: 749 KREEEERKRQEELRRQ--QEEILRRQQEEERKRREE----EELARRKQEEALRRQREQEI 802
Query: 206 LLHQEKLEREQQQ 218
L +++ E E+QQ
Sbjct: 803 ALRRQREEEERQQ 815
Score = 31.6 bits (70), Expect = 1.1
Identities = 51/265 (19%), Positives = 97/265 (36%), Gaps = 64/265 (24%)
Query: 36 LTPETQRDQERRIRREIANSNE-------------RRRMQSINAGFQSLKTLIPHTDGEK 82
L + ++ERR + E+ E +RR++ + + H + E+
Sbjct: 823 LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEER 882
Query: 83 LSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDI 142
K +Q+ E L++Q Q + ++ L +++ A+ K + S
Sbjct: 883 KRKELEVQRQKE-----------LMRQRQQQQEALRRLQQQQQQQQLAQMK---LPSSST 928
Query: 143 WEDEKAEDLRREMIELR----QQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQ 198
W + + L Q+L++ER E Q+R + E +K + QQ Q Q
Sbjct: 929 WGQQSNTTACQSQATLSLAEIQKLEEER------ERQLREEQRRQQRELMKALQQQQQQQ 982
Query: 199 QQ---------------QEQVRLLHQEKLEREQQQLRTQLLPPPAPTHHPTVIVPAPPPP 243
QQ + + + +E + ++QQ + Q P + T
Sbjct: 983 QQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNT--------- 1033
Query: 244 PSHHINVVTMGPSSVINSVSTSRQN 268
H N+ T +SV S++T N
Sbjct: 1034 ---HSNLHTSIGNSVWGSINTGPPN 1055
Score = 29.6 bits (65), Expect = 4.0
Identities = 32/158 (20%), Positives = 62/158 (39%), Gaps = 8/158 (5%)
Query: 134 DEGIGSPDIWEDEKAEDLRREMIELRQQLDK--ERSVRMMLEEQVRSLEAHMYPEKLKVI 191
+E PD ++ E R +E ++ + S R +S EA + K +
Sbjct: 342 NEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPK 401
Query: 192 AQQVQLQQQQEQVRLLHQEKLEREQQQLRTQLLPP----PAPTHHPTVIVPAPPPPPSHH 247
+Q + +++ ++ K+ ++ + P P+ T P +I+P P P PS
Sbjct: 402 TEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPT 461
Query: 248 INVVTMGPSSVINSVSTSRQNLDTIVQAIQHIEGTQEK 285
+ V S S + D + ++H+E EK
Sbjct: 462 LRPVETPVVGAPGMGSVSTEPDDE--EGLKHLEQQAEK 497
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 47.4 bits (111), Expect = 2e-05
Identities = 61/259 (23%), Positives = 113/259 (43%), Gaps = 55/259 (21%)
Query: 39 ETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFS 98
E +R QE +RR+ +RR + + + + A+ +Q + I
Sbjct: 760 ELRRQQEEILRRQQEEERKRREEEEL---------------ARRKQEEALRRQREQEIAL 804
Query: 99 LEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAED---KDEGIGSPDIWEDEKAEDLRREM 155
Q + QQ + R ++E +RR+ E+ K E + E+E+A+ R +
Sbjct: 805 RRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQ---RRL 861
Query: 156 IELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLERE 215
E R ++++E + R+ EE+ R + +L+V Q+ ++Q+Q+Q L + + +++
Sbjct: 862 EENRLRMEEE-AARLRHEEEERKRK------ELEVQRQKELMRQRQQQQEALRRLQQQQQ 914
Query: 216 QQQLRTQLLPPPAPTHHPTVIVPAPPPPPSHHINVVTMGPSSVINSVSTSRQNLDTIVQA 275
QQQL LP + T G S N+ + Q ++ +
Sbjct: 915 QQQLAQMKLPSSS-----------------------TWGQQS--NTTACQSQATLSLAE- 948
Query: 276 IQHIEGTQEKQELEEEQRR 294
IQ +E +E+Q L EEQRR
Sbjct: 949 IQKLEEERERQ-LREEQRR 966
Score = 38.1 bits (87), Expect = 0.011
Identities = 27/87 (31%), Positives = 50/87 (57%), Gaps = 6/87 (6%)
Query: 144 EDEKAEDLRREMIE-LRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIA-----QQVQL 197
E ++ E+LRR+ E LR+Q ++ER R E R E + ++ + IA ++ +
Sbjct: 754 ERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEER 813
Query: 198 QQQQEQVRLLHQEKLEREQQQLRTQLL 224
QQQ+E +R L + + E E+++ + +LL
Sbjct: 814 QQQEEALRRLEERRREEEERRKQEELL 840
Score = 37.7 bits (86), Expect = 0.015
Identities = 39/146 (26%), Positives = 65/146 (44%), Gaps = 19/146 (13%)
Query: 90 QQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEG--------IGSPD 141
QQ A +Q+ LLQQ LK I + + R D G P
Sbjct: 643 QQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPT 702
Query: 142 IWEDEKAEDLRREM------IELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQV 195
+WE DL + +E QQL+K ++ + LE++ R E E+ + +Q
Sbjct: 703 VWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAK--LEQERREAEMRAKREE-EERKRQE 759
Query: 196 QLQQQQEQV--RLLHQEKLEREQQQL 219
+L++QQE++ R +E+ RE+++L
Sbjct: 760 ELRRQQEEILRRQQEEERKRREEEEL 785
Score = 31.6 bits (70), Expect = 1.1
Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 6/73 (8%)
Query: 146 EKAEDLRREMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVR 205
++ E+ R+ ELR+Q +E +R EE+ + E E+L Q+ L++Q+EQ
Sbjct: 749 KREEEERKRQEELRRQ--QEEILRRQQEEERKRREE----EELARRKQEEALRRQREQEI 802
Query: 206 LLHQEKLEREQQQ 218
L +++ E E+QQ
Sbjct: 803 ALRRQREEEERQQ 815
Score = 31.6 bits (70), Expect = 1.1
Identities = 51/265 (19%), Positives = 97/265 (36%), Gaps = 64/265 (24%)
Query: 36 LTPETQRDQERRIRREIANSNE-------------RRRMQSINAGFQSLKTLIPHTDGEK 82
L + ++ERR + E+ E +RR++ + + H + E+
Sbjct: 823 LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEER 882
Query: 83 LSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDI 142
K +Q+ E L++Q Q + ++ L +++ A+ K + S
Sbjct: 883 KRKELEVQRQKE-----------LMRQRQQQQEALRRLQQQQQQQQLAQMK---LPSSST 928
Query: 143 WEDEKAEDLRREMIELR----QQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQ 198
W + + L Q+L++ER E Q+R + E +K + QQ Q Q
Sbjct: 929 WGQQSNTTACQSQATLSLAEIQKLEEER------ERQLREEQRRQQRELMKALQQQQQQQ 982
Query: 199 QQ---------------QEQVRLLHQEKLEREQQQLRTQLLPPPAPTHHPTVIVPAPPPP 243
QQ + + + +E + ++QQ + Q P + T
Sbjct: 983 QQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNT--------- 1033
Query: 244 PSHHINVVTMGPSSVINSVSTSRQN 268
H N+ T +SV S++T N
Sbjct: 1034 ---HSNLHTSIGNSVWGSINTGPPN 1055
Score = 29.6 bits (65), Expect = 4.0
Identities = 32/158 (20%), Positives = 62/158 (39%), Gaps = 8/158 (5%)
Query: 134 DEGIGSPDIWEDEKAEDLRREMIELRQQLDK--ERSVRMMLEEQVRSLEAHMYPEKLKVI 191
+E PD ++ E R +E ++ + S R +S EA + K +
Sbjct: 342 NEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPK 401
Query: 192 AQQVQLQQQQEQVRLLHQEKLEREQQQLRTQLLPP----PAPTHHPTVIVPAPPPPPSHH 247
+Q + +++ ++ K+ ++ + P P+ T P +I+P P P PS
Sbjct: 402 TEQTEKAEEETRMENSLPAKVPSRGDEMVADVQQPLSQIPSDTASPLLILPPPVPNPSPT 461
Query: 248 INVVTMGPSSVINSVSTSRQNLDTIVQAIQHIEGTQEK 285
+ V S S + D + ++H+E EK
Sbjct: 462 LRPVETPVVGAPGMGSVSTEPDDE--EGLKHLEQQAEK 497
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.349
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,057,971
Number of Sequences: 37866
Number of extensions: 724444
Number of successful extensions: 13010
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 352
Number of HSP's successfully gapped in prelim test: 798
Number of HSP's that attempted gapping in prelim test: 7559
Number of HSP's gapped (non-prelim): 4023
length of query: 338
length of database: 18,247,518
effective HSP length: 103
effective length of query: 235
effective length of database: 14,347,320
effective search space: 3371620200
effective search space used: 3371620200
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.