BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4507033 solute carrier family 5 (sodium/glucose cotransporter), member 2 [Homo sapiens] (672 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4507033 solute carrier family 5 (sodium/glucose cotransporter... 1355 0.0 gi|4507031 solute carrier family 5 (sodium/glucose cotransporter... 834 0.0 gi|14140236 solute carrier family 5 (low affinity glucose cotran... 785 0.0 gi|206597483 solute carrier family 5 (sodium/glucose cotransport... 749 0.0 gi|206597487 solute carrier family 5 (sodium/glucose cotransport... 736 0.0 gi|17941285 solute carrier family 5 (sodium/glucose cotransporte... 676 0.0 gi|109659836 solute carrier family 5 (sodium/glucose cotransport... 652 0.0 gi|109659839 solute carrier family 5 (sodium/glucose cotransport... 642 0.0 gi|110835708 solute carrier family 5 (inositol transporters), me... 608 e-174 gi|4507035 solute carrier family 5 (sodium iodide symporter), me... 114 4e-25 gi|157671931 solute carrier family 5 (sodium/glucose cotransport... 107 5e-23 gi|10863879 solute carrier family 5 (sodium-dependent vitamin tr... 99 1e-20 gi|167466278 solute carrier family 5 (iodide transporter), membe... 95 2e-19 gi|11141885 solute carrier family 5 (choline transporter), membe... 94 5e-19 gi|31881740 solute carrier family 12 (potassium/chloride transpo... 35 0.17 gi|21361581 solute carrier family 6 (neurotransmitter transporte... 33 0.66 gi|52627158 olfactory receptor, family 6, subfamily N, member 2 ... 32 1.9 gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens] 31 3.3 gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens] 31 3.3 gi|149274607 solute carrier family 25, member 41 [Homo sapiens] 31 3.3 gi|7657587 solute carrier family 6 (neurotransmitter transporter... 31 4.2 gi|239757591 PREDICTED: hypothetical protein XP_002345493 [Homo ... 30 7.2 >gi|4507033 solute carrier family 5 (sodium/glucose cotransporter), member 2 [Homo sapiens] Length = 672 Score = 1355 bits (3507), Expect = 0.0 Identities = 672/672 (100%), Positives = 672/672 (100%) Query: 1 MEEHTEAGSAPEMGAQKALIDNPADILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGR 60 MEEHTEAGSAPEMGAQKALIDNPADILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGR Sbjct: 1 MEEHTEAGSAPEMGAQKALIDNPADILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGR 60 Query: 61 SMVWWPVGASLFASNIGSGHFVGLAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTA 120 SMVWWPVGASLFASNIGSGHFVGLAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTA Sbjct: 61 SMVWWPVGASLFASNIGSGHFVGLAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTA 120 Query: 121 GVITMPQYLRKRFGGRRIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIA 180 GVITMPQYLRKRFGGRRIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIA Sbjct: 121 GVITMPQYLRKRFGGRRIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIA 180 Query: 181 LLGITMIYTVTGGLAALMYTDTVQTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSL 240 LLGITMIYTVTGGLAALMYTDTVQTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSL Sbjct: 181 LLGITMIYTVTGGLAALMYTDTVQTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSL 240 Query: 241 TVSEDPAVGNISSFCYRPRPDSYHLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQR 300 TVSEDPAVGNISSFCYRPRPDSYHLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQR Sbjct: 241 TVSEDPAVGNISSFCYRPRPDSYHLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQR 300 Query: 301 CLAGKSLTHIKAGCILCGYLKLTPMFLMVMPGMISRILYPDEVACVVPEVCRRVCGTEVG 360 CLAGKSLTHIKAGCILCGYLKLTPMFLMVMPGMISRILYPDEVACVVPEVCRRVCGTEVG Sbjct: 301 CLAGKSLTHIKAGCILCGYLKLTPMFLMVMPGMISRILYPDEVACVVPEVCRRVCGTEVG 360 Query: 361 CSNIAYPRLVVKLMPNGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDR 420 CSNIAYPRLVVKLMPNGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDR Sbjct: 361 CSNIAYPRLVVKLMPNGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDR 420 Query: 421 ELLLVGRLWVVFIVVVSVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRV 480 ELLLVGRLWVVFIVVVSVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRV Sbjct: 421 ELLLVGRLWVVFIVVVSVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRV 480 Query: 481 NEQGAFWGLIGGLLMGLARLIPEFSFGSGSCVQPSACPAFLCGVHYLYFAIVLFFCSGLL 540 NEQGAFWGLIGGLLMGLARLIPEFSFGSGSCVQPSACPAFLCGVHYLYFAIVLFFCSGLL Sbjct: 481 NEQGAFWGLIGGLLMGLARLIPEFSFGSGSCVQPSACPAFLCGVHYLYFAIVLFFCSGLL 540 Query: 541 TLTVSLCTAPIPRKHLHRLVFSLRHSKEEREDLDADEQQGSSLPVQNGCPESAMEMNEPQ 600 TLTVSLCTAPIPRKHLHRLVFSLRHSKEEREDLDADEQQGSSLPVQNGCPESAMEMNEPQ Sbjct: 541 TLTVSLCTAPIPRKHLHRLVFSLRHSKEEREDLDADEQQGSSLPVQNGCPESAMEMNEPQ 600 Query: 601 APAPSLFRQCLLWFCGMSRGGVGSPPPLTQEEAAAAARRLEDISEDPSWARVVNLNALLM 660 APAPSLFRQCLLWFCGMSRGGVGSPPPLTQEEAAAAARRLEDISEDPSWARVVNLNALLM Sbjct: 601 APAPSLFRQCLLWFCGMSRGGVGSPPPLTQEEAAAAARRLEDISEDPSWARVVNLNALLM 660 Query: 661 MAVAVFLWGFYA 672 MAVAVFLWGFYA Sbjct: 661 MAVAVFLWGFYA 672 >gi|4507031 solute carrier family 5 (sodium/glucose cotransporter), member 1 [Homo sapiens] Length = 664 Score = 834 bits (2154), Expect = 0.0 Identities = 393/656 (59%), Positives = 519/656 (79%), Gaps = 15/656 (2%) Query: 19 LIDNPADILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGRSMVWWPVGASLFASNIGS 78 LI N ADI +I YF++V+ VGLW+M TNRGTVGG+FLAGRSMVWWP+GASLFASNIGS Sbjct: 22 LIRNAADISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGS 81 Query: 79 GHFVGLAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTAGVITMPQYLRKRFGGRRI 138 GHFVGLAGTGAASG+A+ GFEWNAL +V++LGWLF P+Y+ AGV+TMP+YLRKRFGG+RI Sbjct: 82 GHFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGQRI 141 Query: 139 RLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALM 198 ++YLS+LSL LYIFTKIS D+FSGA+FI ALG N+Y ++ LL IT +YT+TGGLAA++ Sbjct: 142 QVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVI 201 Query: 199 YTDTVQTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSLTVSEDPAVGNISSFCYRP 258 YTDT+QT ++L G+ IL G+AFHEVGGY +KY+ A ++ + CY P Sbjct: 202 YTDTLQTVIMLVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVSDGNTT---FQEKCYTP 258 Query: 259 RPDSYHLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKSLTHIKAGCILCG 318 R DS+H+ R P+TGDLPWP + G++I++ WYWC+DQVIVQRCL+ K+++H+K GCILCG Sbjct: 259 RADSFHIFRDPLTGDLPWPGFIFGMSILTLWYWCTDQVIVQRCLSAKNMSHVKGGCILCG 318 Query: 319 YLKLTPMFLMVMPGMISRILYPDEVACVVPEVCRRVCGTEVGCSNIAYPRLVVKLMPNGL 378 YLKL PMF+MVMPGMISRILY +++ACVVP C + CGT+VGC+NIAYP LVV+LMPNGL Sbjct: 319 YLKLMPMFIMVMPGMISRILYTEKIACVVPSECEKYCGTKVGCTNIAYPTLVVELMPNGL 378 Query: 379 RGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGRLWVVFIVVVSV 438 RGLML+VMLA+LMSSL SIFNS+STLFTMDIY ++R RA ++EL++ GRL+++ ++ +S+ Sbjct: 379 RGLMLSVMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEKELMIAGRLFILVLIGISI 438 Query: 439 AWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFWGLIGGLLMGLA 498 AW+P+VQ+AQ GQLFDYIQ+++SYL PP++AVF+LA+F RVNE GAFWGLI GLL+G++ Sbjct: 439 AWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWGLILGLLIGIS 498 Query: 499 RLIPEFSFGSGSCVQPSACPAFLCGVHYLYFAIVLFFCSGLLTLTVSLCTAPIPRKHLHR 558 R+I EF++G+GSC++PS CP +CGVHYLYFAI+LF S + + +SL T PIP HL+R Sbjct: 499 RMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFAISFITIVVISLLTKPIPDVHLYR 558 Query: 559 LVFSLRHSKEEREDLDADEQQGSSLPVQNGCPESAMEMNEPQAP--APSLFRQCLLWFCG 616 L +SLR+SKEER DLDA+E+ +Q G P+ +E+ E Q P +FR+ FCG Sbjct: 559 LCWSLRNSKEERIDLDAEEEN-----IQEG-PKETIEI-ETQVPEKKKGIFRRAYDLFCG 611 Query: 617 MSRGGVGSPPPLTQEEAAAAARRLEDISEDPSWARVVNLNALLMMAVAVFLWGFYA 672 + + G P +T+EE A ++ D SE P W V+N+N ++++ VAVF ++A Sbjct: 612 LEQHGA---PKMTEEEEKAMKMKMTDTSEKPLWRTVLNVNGIILVTVAVFCHAYFA 664 >gi|14140236 solute carrier family 5 (low affinity glucose cotransporter), member 4 [Homo sapiens] Length = 659 Score = 785 bits (2027), Expect = 0.0 Identities = 371/653 (56%), Positives = 499/653 (76%), Gaps = 16/653 (2%) Query: 20 IDNPADILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGRSMVWWPVGASLFASNIGSG 79 I N ADI VI YFL+V+ VGLW+M +TNRGT+GG+FLAGR M WWP+GASLFASNIGS Sbjct: 23 IRNAADISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSN 82 Query: 80 HFVGLAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTAGVITMPQYLRKRFGGRRIR 139 H+VGLAGTGAASG+A FEW + ++L+LGW+F P+Y+ +GV+TMP+YL+KRFGG R++ Sbjct: 83 HYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGVMTMPEYLKKRFGGERLQ 142 Query: 140 LYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALMY 199 +YLS+LSLF+ + IS D+F+GA+FI+ ALG ++Y ++ LL +T +YT TGGLA+++Y Sbjct: 143 VYLSILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIY 202 Query: 200 TDTVQTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSLTVSEDPAVGNISSFCYRPR 259 TDT+QT ++L G+ ILMG+AF+EVGGY +KY+ A S+ ++ IS+ CY PR Sbjct: 203 TDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLT---ISASCYTPR 259 Query: 260 PDSYHLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKSLTHIKAGCILCGY 319 DS+H+ R VTGD+PWP ++ G+ I + WYWC++QVIVQRCL GK ++H+KA CI+C Y Sbjct: 260 ADSFHIFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSHVKAACIMCAY 319 Query: 320 LKLTPMFLMVMPGMISRILYPDEVACVVPEVCRRVCGTEVGCSNIAYPRLVVKLMPNGLR 379 LKL PMFLMVMPGMISRILY D VACVVP C + CG +VGC+N AYP +V++LMP GLR Sbjct: 320 LKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVGCTNYAYPTMVLELMPQGLR 379 Query: 380 GLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGRLWVVFIVVVSVA 439 GLML+VMLA+LMSSL SIFNS+STLFT+D+YT++R +A ++ELL+ GR++V+ + VVS+ Sbjct: 380 GLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKELLIAGRIFVLLLTVVSIV 439 Query: 440 WLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFWGLIGGLLMGLAR 499 W+P+VQ +Q GQL Y +++SSYL PP++AVFVLA+F RVNEQGAFWGL+ GL MGL R Sbjct: 440 WVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWGLMVGLAMGLIR 499 Query: 500 LIPEFSFGSGSCVQPSACPAFLCGVHYLYFAIVLFFCSGLLTLTVSLCTAPIPRKHLHRL 559 +I EF++G+GSC+ PS CP +CGVHYLYF+IVLFF S L+TL +SL T PIP HL+RL Sbjct: 500 MITEFAYGTGSCLAPSNCPKIICGVHYLYFSIVLFFGSMLVTLGISLLTKPIPDVHLYRL 559 Query: 560 VFSLRHSKEEREDLDADEQQGSSLPVQNGCPESAMEMNEPQAPAPSLFRQCLLWFCGMSR 619 + LR+S EER D+DA+E+ S +G E E + ++ FCG+ + Sbjct: 560 CWVLRNSTEERIDIDAEEK--SQEETDDGVEEDYPEKSR------GCLKKAYDLFCGLQK 611 Query: 620 GGVGSPPPLTQEEAAAAARRLEDISEDPSWARVVNLNALLMMAVAVFLWGFYA 672 G P LT+EE A +++L D SE PSW +VN+NA+L++AV VF+ G+YA Sbjct: 612 G-----PKLTKEEEEALSKKLTDTSERPSWRTIVNINAILLLAVVVFIHGYYA 659 >gi|206597483 solute carrier family 5 (sodium/glucose cotransporter), member 9 isoform 2 [Homo sapiens] Length = 681 Score = 749 bits (1935), Expect = 0.0 Identities = 364/673 (54%), Positives = 494/673 (73%), Gaps = 21/673 (3%) Query: 9 SAPEMGAQKALIDNPADILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGRSMVWWPVG 68 +AP + + + DI V+ YF+ VI VG+WS R +RGT+GGYFLAGRSM WWP+G Sbjct: 21 TAPHIALDSRVGLHAYDISVVVIYFVFVIAVGIWSSIRASRGTIGGYFLAGRSMSWWPIG 80 Query: 69 ASLFASNIGSGHFVGLAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTAGVITMPQY 128 ASL +SN+GSG F+GLAGTGAA GLAV GFEWNA +++L LGW+F PVY+ AGV+TMPQY Sbjct: 81 ASLMSSNVGSGLFIGLAGTGAAGGLAVGGFEWNATWLLLALGWVFVPVYIAAGVVTMPQY 140 Query: 129 LRKRFGGRRIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIY 188 L+KRFGG+RI++Y+SVLSL LYIFTKIS D+FSGA+FIQ ALGWN+Y S LL +T +Y Sbjct: 141 LKKRFGGQRIQVYMSVLSLILYIFTKISTDIFSGALFIQMALGWNLYLSTGILLVVTAVY 200 Query: 189 TVTGGLAALMYTDTVQTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSLTVSEDPAV 248 T+ GGL A++YTD +QT +++GGA +LM F +VG Y GL +Y A ++TV Sbjct: 201 TIAGGLMAVIYTDALQTVIMVGGALVLMFLGFQDVGWYPGLEQRYRQAIPNVTVP----- 255 Query: 249 GNISSFCYRPRPDSYHLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKSLT 308 ++ C+ PRPD++H+LR PV+GD+PWP L+ GLT+++ W WC+DQVIVQR L+ KSL+ Sbjct: 256 ---NTTCHLPRPDAFHILRDPVSGDIPWPGLIFGLTVLATWCWCTDQVIVQRSLSAKSLS 312 Query: 309 HIKAGCILCGYLKLTPMFLMVMPGMISRILYPDEVACVVPEVCRRVCGTEVGCSNIAYPR 368 H K G +L GYLK+ PMF +VMPGMISR L+PDEV CV P+VC+R+CG VGCSNIAYP+ Sbjct: 313 HAKGGSVLGGYLKILPMFFIVMPGMISRALFPDEVGCVDPDVCQRICGARVGCSNIAYPK 372 Query: 369 LVVKLMPNGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGRL 428 LV+ LMP GLRGLM+AV++AALMSSL SIFNSSSTLFT+D++ R R ++ ++EL++VGR+ Sbjct: 373 LVMALMPVGLRGLMIAVIMAALMSSLTSIFNSSSTLFTIDVWQRFRRKSTEQELMVVGRV 432 Query: 429 WVVFIVVVSVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFWG 488 +VVF+VV+S+ W+P++Q++ GQLFDYIQAV+SYLAPP++A+F+LA+F RV E GAFWG Sbjct: 433 FVVFLVVISILWIPIIQSSNSGQLFDYIQAVTSYLAPPITALFLLAIFCKRVTEPGAFWG 492 Query: 489 LIGGLLMGLARLIPEFSFGSGSCVQPSACPAFLCGVHYLYFAIVLFFCSGLLTLTVSLCT 548 L+ GL +GL R+I EFS+ + +C + PA L HYLYFAI+L + ++ + VSLCT Sbjct: 493 LVFGLGVGLLRMILEFSYPAPACGEVDRRPAVLKDFHYLYFAILLCGLTAIVIVIVSLCT 552 Query: 549 APIPRKHLHRLVFSLRH------SKEEREDL-DADEQQGSSLPVQNGCPE-SAMEMNEPQ 600 PIP + L RL + R+ KE E + E+ P G E S++ +P+ Sbjct: 553 TPIPEEQLTRLTWWTRNCPLSELEKEAHESTPEISERPAGECPAGGGAAENSSLGQEQPE 612 Query: 601 APAPSLFRQCLLWFCGMSRGGVGSP-PPLTQEEAAAAARRLEDISEDPSWARVVNLNALL 659 AP+ S + WFCG+S G+P L+ E AA ++L I E+P W V N+NA+L Sbjct: 613 APSRSWGKLLWSWFCGLS----GTPEQALSPAEKAALEQKLTSIEEEPLWRHVCNINAVL 668 Query: 660 MMAVAVFLWGFYA 672 ++A+ +FLWG++A Sbjct: 669 LLAINIFLWGYFA 681 >gi|206597487 solute carrier family 5 (sodium/glucose cotransporter), member 9 isoform 1 [Homo sapiens] Length = 706 Score = 736 bits (1899), Expect = 0.0 Identities = 364/698 (52%), Positives = 494/698 (70%), Gaps = 46/698 (6%) Query: 9 SAPEMGAQKALIDNPADILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGRSMVWWPVG 68 +AP + + + DI V+ YF+ VI VG+WS R +RGT+GGYFLAGRSM WWP+G Sbjct: 21 TAPHIALDSRVGLHAYDISVVVIYFVFVIAVGIWSSIRASRGTIGGYFLAGRSMSWWPIG 80 Query: 69 ASLFASNIGSGHFVGLAGTGAASGLAVAGFEWN-------------------------AL 103 ASL +SN+GSG F+GLAGTGAA GLAV GFEWN A Sbjct: 81 ASLMSSNVGSGLFIGLAGTGAAGGLAVGGFEWNMRKSRSGGDRGIHPRSHGRTGVRSQAT 140 Query: 104 FVVLLLGWLFAPVYLTAGVITMPQYLRKRFGGRRIRLYLSVLSLFLYIFTKISVDMFSGA 163 +++L LGW+F PVY+ AGV+TMPQYL+KRFGG+RI++Y+SVLSL LYIFTKIS D+FSGA Sbjct: 141 WLLLALGWVFVPVYIAAGVVTMPQYLKKRFGGQRIQVYMSVLSLILYIFTKISTDIFSGA 200 Query: 164 VFIQQALGWNIYASVIALLGITMIYTVTGGLAALMYTDTVQTFVILGGACILMGYAFHEV 223 +FIQ ALGWN+Y S LL +T +YT+ GGL A++YTD +QT +++GGA +LM F +V Sbjct: 201 LFIQMALGWNLYLSTGILLVVTAVYTIAGGLMAVIYTDALQTVIMVGGALVLMFLGFQDV 260 Query: 224 GGYSGLFDKYLGAATSLTVSEDPAVGNISSFCYRPRPDSYHLLRHPVTGDLPWPALLLGL 283 G Y GL +Y A ++TV ++ C+ PRPD++H+LR PV+GD+PWP L+ GL Sbjct: 261 GWYPGLEQRYRQAIPNVTVP--------NTTCHLPRPDAFHILRDPVSGDIPWPGLIFGL 312 Query: 284 TIVSGWYWCSDQVIVQRCLAGKSLTHIKAGCILCGYLKLTPMFLMVMPGMISRILYPDEV 343 T+++ W WC+DQVIVQR L+ KSL+H K G +L GYLK+ PMF +VMPGMISR L+PDEV Sbjct: 313 TVLATWCWCTDQVIVQRSLSAKSLSHAKGGSVLGGYLKILPMFFIVMPGMISRALFPDEV 372 Query: 344 ACVVPEVCRRVCGTEVGCSNIAYPRLVVKLMPNGLRGLMLAVMLAALMSSLASIFNSSST 403 CV P+VC+R+CG VGCSNIAYP+LV+ LMP GLRGLM+AV++AALMSSL SIFNSSST Sbjct: 373 GCVDPDVCQRICGARVGCSNIAYPKLVMALMPVGLRGLMIAVIMAALMSSLTSIFNSSST 432 Query: 404 LFTMDIYTRLRPRAGDRELLLVGRLWVVFIVVVSVAWLPVVQAAQGGQLFDYIQAVSSYL 463 LFT+D++ R R ++ ++EL++VGR++VVF+VV+S+ W+P++Q++ GQLFDYIQAV+SYL Sbjct: 433 LFTIDVWQRFRRKSTEQELMVVGRVFVVFLVVISILWIPIIQSSNSGQLFDYIQAVTSYL 492 Query: 464 APPVSAVFVLALFVPRVNEQGAFWGLIGGLLMGLARLIPEFSFGSGSCVQPSACPAFLCG 523 APP++A+F+LA+F RV E GAFWGL+ GL +GL R+I EFS+ + +C + PA L Sbjct: 493 APPITALFLLAIFCKRVTEPGAFWGLVFGLGVGLLRMILEFSYPAPACGEVDRRPAVLKD 552 Query: 524 VHYLYFAIVLFFCSGLLTLTVSLCTAPIPRKHLHRLVFSLRH------SKEEREDL-DAD 576 HYLYFAI+L + ++ + VSLCT PIP + L RL + R+ KE E + Sbjct: 553 FHYLYFAILLCGLTAIVIVIVSLCTTPIPEEQLTRLTWWTRNCPLSELEKEAHESTPEIS 612 Query: 577 EQQGSSLPVQNGCPE-SAMEMNEPQAPAPSLFRQCLLWFCGMSRGGVGSP-PPLTQEEAA 634 E+ P G E S++ +P+AP+ S + WFCG+S G+P L+ E A Sbjct: 613 ERPAGECPAGGGAAENSSLGQEQPEAPSRSWGKLLWSWFCGLS----GTPEQALSPAEKA 668 Query: 635 AAARRLEDISEDPSWARVVNLNALLMMAVAVFLWGFYA 672 A ++L I E+P W V N+NA+L++A+ +FLWG++A Sbjct: 669 ALEQKLTSIEEEPLWRHVCNINAVLLLAINIFLWGYFA 706 >gi|17941285 solute carrier family 5 (sodium/glucose cotransporter), member 11 [Homo sapiens] Length = 675 Score = 676 bits (1745), Expect = 0.0 Identities = 340/692 (49%), Positives = 470/692 (67%), Gaps = 37/692 (5%) Query: 1 MEEHTEAGSAPEMGA-----QKALIDNPADILVIAAYFLLVIGVGLWSMCRTNRGTVGGY 55 ME T + P++ QK L P DI V+ YFL V+ VGLWS +T R TV GY Sbjct: 1 MESGTSSPQPPQLDPLDAFPQKGL--EPGDIAVLVLYFLFVLAVGLWSTVKTKRDTVKGY 58 Query: 56 FLAGRSMVWWPVGASLFASNIGSGHFVGLAGTGAASGLAVAGFEWNALFVVLLLGWLFAP 115 FLAG MVWWPVGASLFASN+GSGHF+GLAG+GAA+G++V+ +E N LF VL+L W+F P Sbjct: 59 FLAGGDMVWWPVGASLFASNVGSGHFIGLAGSGAATGISVSAYELNGLFSVLMLAWIFLP 118 Query: 116 VYLTAGVITMPQYLRKRFGGRRIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIY 175 +Y+ V TMP+YLRKRFGG RI + L+VL LF+YIFTKISVDM++GA+FIQQ+L ++Y Sbjct: 119 IYIAGQVTTMPEYLRKRFGGIRIPIILAVLYLFIYIFTKISVDMYAGAIFIQQSLHLDLY 178 Query: 176 ASVIALLGITMIYTVTGGLAALMYTDTVQTFVILGGACILMGYAFHEVGGYSGLFDKYLG 235 +++ LL IT +YTV GGLAA++YTD +QT ++L GA LMGY+F VGG GL +KY Sbjct: 179 LAIVGLLAITAVYTVAGGLAAVIYTDALQTLIMLIGALTLMGYSFAAVGGMEGLKEKYFL 238 Query: 236 AATSLTVSEDPAVGNISSFCYRPRPDSYHLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQ 295 A S SE+ S C PR D++H+ R P+T DLPWP +L G++I S WYWC+DQ Sbjct: 239 ALAS-NRSEN-------SSCGLPREDAFHIFRDPLTSDLPWPGVLFGMSIPSLWYWCTDQ 290 Query: 296 VIVQRCLAGKSLTHIKAGCILCGYLKLTPMFLMVMPGMISRILYPDEVACVVPEVCRRVC 355 VIVQR LA K+L+H K G ++ YLK+ P+F+MV PGM+SRIL+PD+VAC PE+C+++C Sbjct: 291 VIVQRTLAAKNLSHAKGGALMAAYLKVLPLFIMVFPGMVSRILFPDQVACADPEICQKIC 350 Query: 356 GTEVGCSNIAYPRLVVKLMPNGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRP 415 GCS+IAYP+LV++L+P GLRGLM+AVM+AALMSSL SIFNS+ST+FTMD++ LRP Sbjct: 351 SNPSGCSDIAYPKLVLELLPTGLRGLMMAVMVAALMSSLTSIFNSASTIFTMDLWNHLRP 410 Query: 416 RAGDRELLLVGRLWVVFIVVVSVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLAL 475 RA ++EL++VGR++V+ +V+VS+ W+PVVQA+QGGQLF YIQ++SSYL PPV+ VF++ Sbjct: 411 RASEKELMIVGRVFVLLLVLVSILWIPVVQASQGGQLFIYIQSISSYLQPPVAVVFIMGC 470 Query: 476 FVPRVNEQGAFWGLIGGLLMGLARLIPEFSFGSGSCVQPSACPAFLCGVHYLYFAIVLFF 535 F R NE+GAFWGLI GLL+GL RL+ +F + C QP P + +HYLYF+++L Sbjct: 471 FWKRTNEKGAFWGLISGLLLGLVRLVLDFIYVQPRCDQPDERPVLVKSIHYLYFSMILST 530 Query: 536 CSGLLTLTVSLCTAPIPRKHLHRLVFSLRHSKEEREDLDADEQQGSSLPVQNGCPESA-- 593 + + TVS T P ++ + L + RH +++ S QNG PE++ Sbjct: 531 VTLITVSTVSWFTEPPSKEMVSHLTWFTRHDPVVQKEQAPPAAPLSLTLSQNGMPEASSS 590 Query: 594 ----MEMNE---------PQAPAPSLFRQCLLWFCGMSRGGVGSPPPLTQEEAAAAARRL 640 EM + P S + +LW CG+ G +E A A + Sbjct: 591 SSVQFEMVQENTSKTHSCDMTPKQSKVVKAILWLCGIQEKG-------KEELPARAEAII 643 Query: 641 EDISEDPSWARVVNLNALLMMAVAVFLWGFYA 672 + E+P ++++N + ++ A+F+WG++A Sbjct: 644 VSLEENPLVKTLLDVNLIFCVSCAIFIWGYFA 675 >gi|109659836 solute carrier family 5 (sodium/glucose cotransporter), member 10 isoform 2 [Homo sapiens] Length = 596 Score = 652 bits (1682), Expect = 0.0 Identities = 314/527 (59%), Positives = 401/527 (76%), Gaps = 8/527 (1%) Query: 24 ADILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGRSMVWWPVGASLFASNIGSGHFVG 83 ADI+VI YF L + VG+WS CR +R TV GYFLAGR M WWP+GASLFAS+ GSG F+G Sbjct: 19 ADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGLFIG 78 Query: 84 LAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTAGVITMPQYLRKRFGGRRIRLYLS 143 LAG+GAA GLAVAGFEWNA +V+L L W+F P+Y+++ ++T+P+Y++KR+GG+RIR+YLS Sbjct: 79 LAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRMYLS 138 Query: 144 VLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALMYTDTV 203 VLSL L +FTKIS+D+++GA+F+ LGWN Y S I LGIT +YT+ GGLAA++YTD + Sbjct: 139 VLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYTDAL 198 Query: 204 QTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSLTVSEDPAVGNISSFCYRPRPDSY 263 QT +++ GA IL AF ++GGY L Y A S T++ ++ C+ PR D+ Sbjct: 199 QTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIA--------NTTCHLPRTDAM 250 Query: 264 HLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKSLTHIKAGCILCGYLKLT 323 H+ R P TGDLPW + GLTI++ WYWC+DQVIVQR L+ + L H KAG IL YLK+ Sbjct: 251 HMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKML 310 Query: 324 PMFLMVMPGMISRILYPDEVACVVPEVCRRVCGTEVGCSNIAYPRLVVKLMPNGLRGLML 383 PM L++MPGMISR L+PD+V CVVP C R CG EVGCSNIAYP+LV++LMP GLRGLM+ Sbjct: 311 PMGLIIMPGMISRALFPDDVGCVVPSECLRACGAEVGCSNIAYPKLVMELMPIGLRGLMI 370 Query: 384 AVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGRLWVVFIVVVSVAWLPV 443 AVMLAALMSSL SIFNSSSTLFTMDI+ RLRPR+G+RELLLVGRL +V ++ VSVAW+PV Sbjct: 371 AVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRLVIVALIGVSVAWIPV 430 Query: 444 VQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFWGLIGGLLMGLARLIPE 503 +Q + GQLF Y+Q+V+S LAPPV+AVFVL +F R NEQGAFWGLI GL++G RL+ E Sbjct: 431 LQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGLIAGLVVGATRLVLE 490 Query: 504 FSFGSGSCVQPSACPAFLCGVHYLYFAIVLFFCSGLLTLTVSLCTAP 550 F + C +P PA L +HYL+FA+ LF SG + + SL T P Sbjct: 491 FLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALSGAVVVAGSLLTPP 537 Score = 31.2 bits (69), Expect = 3.3 Identities = 11/24 (45%), Positives = 17/24 (70%) Query: 649 WARVVNLNALLMMAVAVFLWGFYA 672 WARV NA+L+M V +F + ++A Sbjct: 573 WARVCGFNAILLMCVNIFFYAYFA 596 >gi|109659839 solute carrier family 5 (sodium/glucose cotransporter), member 10 isoform 1 [Homo sapiens] Length = 612 Score = 642 bits (1655), Expect = 0.0 Identities = 314/543 (57%), Positives = 401/543 (73%), Gaps = 24/543 (4%) Query: 24 ADILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGRSMVWWPVGASLFASNIGSGHFVG 83 ADI+VI YF L + VG+WS CR +R TV GYFLAGR M WWP+GASLFAS+ GSG F+G Sbjct: 19 ADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGLFIG 78 Query: 84 LAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTAGVITMPQYLRKRFGGRRIRLYLS 143 LAG+GAA GLAVAGFEWNA +V+L L W+F P+Y+++ ++T+P+Y++KR+GG+RIR+YLS Sbjct: 79 LAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRMYLS 138 Query: 144 VLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALMYTDTV 203 VLSL L +FTKIS+D+++GA+F+ LGWN Y S I LGIT +YT+ GGLAA++YTD + Sbjct: 139 VLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYTDAL 198 Query: 204 QTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSLTVSEDPAVGNISSFCYRPRPDSY 263 QT +++ GA IL AF ++GGY L Y A S T++ ++ C+ PR D+ Sbjct: 199 QTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIA--------NTTCHLPRTDAM 250 Query: 264 HLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKSLTHIKAGCILCGYLKLT 323 H+ R P TGDLPW + GLTI++ WYWC+DQVIVQR L+ + L H KAG IL YLK+ Sbjct: 251 HMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKML 310 Query: 324 PMFLMVMPGMISRILYP----------------DEVACVVPEVCRRVCGTEVGCSNIAYP 367 PM L++MPGMISR L+P D+V CVVP C R CG EVGCSNIAYP Sbjct: 311 PMGLIIMPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEVGCSNIAYP 370 Query: 368 RLVVKLMPNGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGR 427 +LV++LMP GLRGLM+AVMLAALMSSL SIFNSSSTLFTMDI+ RLRPR+G+RELLLVGR Sbjct: 371 KLVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGR 430 Query: 428 LWVVFIVVVSVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFW 487 L +V ++ VSVAW+PV+Q + GQLF Y+Q+V+S LAPPV+AVFVL +F R NEQGAFW Sbjct: 431 LVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFW 490 Query: 488 GLIGGLLMGLARLIPEFSFGSGSCVQPSACPAFLCGVHYLYFAIVLFFCSGLLTLTVSLC 547 GLI GL++G RL+ EF + C +P PA L +HYL+FA+ LF SG + + SL Sbjct: 491 GLIAGLVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALSGAVVVAGSLL 550 Query: 548 TAP 550 T P Sbjct: 551 TPP 553 Score = 31.2 bits (69), Expect = 3.3 Identities = 11/24 (45%), Positives = 17/24 (70%) Query: 649 WARVVNLNALLMMAVAVFLWGFYA 672 WARV NA+L+M V +F + ++A Sbjct: 589 WARVCGFNAILLMCVNIFFYAYFA 612 >gi|110835708 solute carrier family 5 (inositol transporters), member 3 [Homo sapiens] Length = 718 Score = 608 bits (1569), Expect = e-174 Identities = 291/563 (51%), Positives = 414/563 (73%), Gaps = 2/563 (0%) Query: 17 KALIDNPADILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGRSMVWWPVGASLFASNI 76 +A++D ADI ++A YF+LV+ +G ++M ++NR TV GYFLAGRSM W +GASLF SNI Sbjct: 2 RAVLDT-ADIAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVTIGASLFVSNI 60 Query: 77 GSGHFVGLAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTAGVITMPQYLRKRFGGR 136 GS HF+GLAG+GAASG AV +E+NAL ++ LLGW+F P+Y+ +GV TMP+YL KRFGG Sbjct: 61 GSEHFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGH 120 Query: 137 RIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAA 196 RI++Y + LSL LYIFTK+SVD++SGA+FIQ++LGWN+Y SVI L+G+T + TVTGGL A Sbjct: 121 RIQVYFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVA 180 Query: 197 LMYTDTVQTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSLT-VSEDPAVGNISSFC 255 ++YTDT+Q +++ GA LM + E+GG+ + +Y+ A+ +T + + N +S Sbjct: 181 VIYTDTLQALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCN 240 Query: 256 YRPRPDSYHLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKSLTHIKAGCI 315 P+ ++ +LR+P D+PWP +LG T S WYWC+DQVIVQR LA K++ H K + Sbjct: 241 VSPKKEALKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTL 300 Query: 316 LCGYLKLTPMFLMVMPGMISRILYPDEVACVVPEVCRRVCGTEVGCSNIAYPRLVVKLMP 375 + G+LKL PMF++V+PGMISRIL+ D++AC+ PE C VCG+ GCSNIAYPRLV+KL+P Sbjct: 301 MAGFLKLLPMFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMKLVP 360 Query: 376 NGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGRLWVVFIVV 435 GLRGLM+AVM+AALMS L SIFNS+ST+FT+D+Y +R A REL++VGR++V F+VV Sbjct: 361 VGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVV 420 Query: 436 VSVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFWGLIGGLLM 495 +S+AW+P++ QGGQ++ YIQ V+ YL PPV+A+F+LA+F R NEQGAF+G + G ++ Sbjct: 421 ISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVL 480 Query: 496 GLARLIPEFSFGSGSCVQPSACPAFLCGVHYLYFAIVLFFCSGLLTLTVSLCTAPIPRKH 555 G RLI F++ + C QP P F+ +HY+Y A LF+ +GL+T+ VSL T P ++ Sbjct: 481 GAVRLILAFAYRAPECDQPDNRPGFIKDIHYMYVATGLFWVTGLITVIVSLLTPPPTKEQ 540 Query: 556 LHRLVFSLRHSKEEREDLDADEQ 578 + F + + +E+ E+ Sbjct: 541 IRTTTFWSKKNLVVKENCSPKEE 563 >gi|4507035 solute carrier family 5 (sodium iodide symporter), member 5 [Homo sapiens] Length = 643 Score = 114 bits (284), Expect = 4e-25 Identities = 122/503 (24%), Positives = 212/503 (42%), Gaps = 55/503 (10%) Query: 3 EHTEAGSAPEMGAQKALIDNPADILVIAAYFLLVIGVGLW-SMCRTNRGTVGGYFLAGRS 61 E E G P GA D V A L+ G+GLW + R + + +F GR Sbjct: 2 EAVETGERPTFGAW--------DYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRR 53 Query: 62 MVWWPVGASLFASNIGSGHFVGLAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTAG 121 + PVG SL AS + + +G+ GL L +L LF PV+ G Sbjct: 54 LAALPVGLSLSASFMSAVQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLG 113 Query: 122 VITMPQYLRKRFGGRRIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIAL 181 + + +YL RF R +RL L + + +++ A+ + Q G +I+AS+++ Sbjct: 114 LTSTYEYLEMRFS-RAVRL-CGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLST 171 Query: 182 LGITMIYTVTGGLAALMYTDTVQTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSLT 241 I YT GG+ A+++TD Q V+L G +++ VG G LT Sbjct: 172 GIICTFYTAVGGMKAVVWTDVFQVVVMLSGFWVVLARGVMLVG----------GPRQVLT 221 Query: 242 VSEDPAVGNISSFCYRPRPDSYHLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRC 301 ++++ + N+ F PR Y V G L W ++ + +Q VQR Sbjct: 222 LAQNHSRINLMDFNPDPR-SRYTFWTFVVGGTLVWLSM-----------YGVNQAQVQRY 269 Query: 302 LAGKSLTHIKAGCILCGYLKLTPMFLMVMP----GMISRILYPDEVACVVPEVCRRVCGT 357 +A ++ K + + +FL+V G++ + Y D C + Sbjct: 270 VACRTEKQAKLALL----INQVGLFLIVSSAACCGIVMFVFYTD---------CDPLLLG 316 Query: 358 EVGCSNIAYPRLVVKLMPN--GLRGLMLAVMLAALMSSLASIFNSSSTLFTMD-IYTRLR 414 + + P LV+ + + G+ GL LA + +S+ ++ N+ + + D I RLR Sbjct: 317 RISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRLR 376 Query: 415 PRAGDRELLLVGRLWVVFIVVVSVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLA 474 A R+L+++ + + I + + + + GG + V ++ P+ F+L Sbjct: 377 SLA-PRKLVIISK-GLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFILG 434 Query: 475 LFVPRVNEQGAFWGLIGGLLMGL 497 +F+P N G GL GL + L Sbjct: 435 MFLPACNTPGVLAGLGAGLALSL 457 >gi|157671931 solute carrier family 5 (sodium/glucose cotransporter), member 12 [Homo sapiens] Length = 618 Score = 107 bits (266), Expect = 5e-23 Identities = 117/488 (23%), Positives = 214/488 (43%), Gaps = 44/488 (9%) Query: 25 DILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAG-RSMVWWPVGASLFASNIGSGHFVG 83 D +V AA F + G+G++ + + FL G R M + PVG SL AS + + +G Sbjct: 10 DYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFMSAVTVLG 69 Query: 84 LAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTAGVITMPQYLRKRFGGRRIRLYLS 143 G + F LFV+LL LF PV+ +G+ + +YL+ RF + +R Y + Sbjct: 70 TPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRF-NKPVR-YAA 127 Query: 144 VLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALMYTDTV 203 + + V +++ A+ + Q G++++ SV A + Y GGL A+++TD Sbjct: 128 TVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWTDAF 187 Query: 204 QTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSLTVSEDPAVGNISSFCYRPRPDSY 263 Q V++ G ++ GG+ + ++ S + + +I F P Sbjct: 188 QMVVMIVGFLTVLIQGSTHAGGFHNVLEQ----------STNGSRLHIFDFDVDP----- 232 Query: 264 HLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKSLTHIKAGCILCGYLKLT 323 L RH W + G G Y +Q +QRC++ K+ H K L Y L Sbjct: 233 -LRRHTF-----WTITVGGTFTWLGIYGV-NQSTIQRCISCKTEKHAK----LALYFNLL 281 Query: 324 PMFLMVMPGMISRILYPDEVACVVPEVCRRVCGTEVGCSNIAYPRLVVKL---MPNGLRG 380 ++++++ + S ++ + C + + P V+++ MP GL G Sbjct: 282 GLWIILVCAVFSGLIMYSHF-----KDCDPWTSGIISAPDQLMPYFVMEIFATMP-GLPG 335 Query: 381 LMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGR-LWVVF-IVVVSV 438 L +A + +S++AS N+ +T+ D P D+ + + L ++F ++ S+ Sbjct: 336 LFVACAFSGTLSTVASSINALATVTFEDFVKSCFPHLSDKLSTWISKGLCLLFGVMCTSM 395 Query: 439 AWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFWGLIGGLLMGLA 498 A V A+ G + ++ P+ +F L + P VN +GA GL+ G+ + Sbjct: 396 A----VAASVMGGVVQASLSIHGMCGGPMLGLFSLGIVFPFVNWKGALGGLLTGITLSFW 451 Query: 499 RLIPEFSF 506 I F + Sbjct: 452 VAIGAFIY 459 >gi|10863879 solute carrier family 5 (sodium-dependent vitamin transporter), member 6 [Homo sapiens] Length = 635 Score = 99.4 bits (246), Expect = 1e-20 Identities = 121/501 (24%), Positives = 217/501 (43%), Gaps = 66/501 (13%) Query: 25 DILVIAAYFLLVIGVGLWSMCRT-NRGTVGGYFLAGRSMVWWPVGASLFASNIGSGHFVG 83 D +V +L + +GL+ CR R TVG +A R M PV SL A+ + Sbjct: 28 DYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSA----- 82 Query: 84 LAGTGAASGLAVAGFEWNALFVVLLLGWL-----FAPVYLTAGVITMPQYLRKRFGGRRI 138 +A G S + G ++ L LG L F PV+ + + +YL RF + + Sbjct: 83 VAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRFN-KTV 141 Query: 139 RLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALM 198 R+ +V +F + + V +++ ++ + G++++ SV+AL + +YT GGL A++ Sbjct: 142 RVCGTVTFIFQMVIY-MGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVI 200 Query: 199 YTDTVQTFVILGG--ACILMGYAFHEVGGYSGLFDKYLGAATSLTVSEDPAVGNISSFCY 256 +TD QT V+ G A I++G A +VGG LG ++ G IS F Sbjct: 201 WTDVFQTLVMFLGQLAVIIVGSA--KVGG--------LGRVWAVASQH----GRISGFEL 246 Query: 257 RPRPDSYHLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKSLTHIKAGCIL 316 P P +RH W G+ ++ Y +Q VQR L+ ++ C Sbjct: 247 DPDP----FVRHTF-----WTLAFGGVFMMLSLYGV-NQAQVQRYLSSRTEKAAVLSCYA 296 Query: 317 CGYLKLTPMFLMVMPGMISRILYPDEVACVVPEVCRRVCGTEVGCSNIAYPRLVVKLMPN 376 + + + + G++ Y + + + + + ++K +P Sbjct: 297 VFPFQQVSLCVGCLIGLVMFAYYQEYPMSI------QQAQAAPDQFVLYFVMDLLKGLP- 349 Query: 377 GLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGR-------LW 429 GL GL +A + + +S+++S FNS +T+ D+ P + +++ R L Sbjct: 350 GLPGLFIACLFSGSLSTISSAFNSLATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLL 409 Query: 430 VVFIVVVSVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFWGL 489 + + +S PV+QAA ++ + P+ +F L +F P N GA GL Sbjct: 410 CLGMAYISSQMGPVLQAA---------ISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGL 460 Query: 490 IGGLLM----GLARLIPEFSF 506 + GL+M G+ ++ F Sbjct: 461 LAGLVMAFWIGIGSIVTSMGF 481 >gi|167466278 solute carrier family 5 (iodide transporter), member 8 [Homo sapiens] Length = 610 Score = 94.7 bits (234), Expect = 2e-19 Identities = 110/481 (22%), Positives = 204/481 (42%), Gaps = 48/481 (9%) Query: 25 DILVIAAYFLLVIGVGLW-SMCRTNRGTVGGYFLAGRSMVWWPVGASLFASNIGSGHFVG 83 D +V A ++ +G++ + + T + + GR M PV SL AS + + +G Sbjct: 14 DYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFMSAVTVLG 73 Query: 84 LAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTAGVITMPQYLRKRFGGRRIRLYLS 143 G + F + FVV++ +F PV+ G+ + +YL RF + +RL + Sbjct: 74 TPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRF-NKCVRLCGT 132 Query: 144 VLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALMYTDTV 203 VL + I + +++ A+ + Q G++++ +V+A + Y GGL A+++TD Sbjct: 133 VLFIVQTIL-YTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVIWTDVF 191 Query: 204 QTFVILGGACILMGYAFHEVGGYSGLF-DKYLGAATSLTVSEDPAVGNISSFCYRPRPDS 262 Q +++ G ++ A GG S + D Y G G ++ + + P P Sbjct: 192 QVGIMVAGFASVIIQAVVMQGGISTILNDAYDG-------------GRLNFWNFNPNP-- 236 Query: 263 YHLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKSLTHIKAGCILCGYLKL 322 L RH W +++G T + +Q VQR ++ KS K L Y+ L Sbjct: 237 --LQRHTF-----W-TIIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAK----LSLYINL 284 Query: 323 TPMFLM----VMPGMISRILYPDEVACVVPEVCRRVCGTEVGCSNIAYPRLVVKLMPN-- 376 ++ + V G+ Y D C +V + P LV+ ++ + Sbjct: 285 VGLWAILTCSVFCGLALYSRYHD---------CDPWTAKKVSAPDQLMPYLVLDILQDYP 335 Query: 377 GLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGRLWVVFIVVV 436 GL GL +A + +S+++S N+ + + D+ +R L + + V + Sbjct: 336 GLPGLFVACAYSGTLSTVSSSINALAAVTVEDLIKPYFRSLSERSLSWISQGMSVVYGAL 395 Query: 437 SVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFWGLIGGLLMG 496 + + A+ G L +V + P+ +F L + VP N GA GL+ G + Sbjct: 396 CIGMAAL--ASLMGALLQAALSVFGMVGGPLMGLFALGILVPFANSIGALVGLMAGFAIS 453 Query: 497 L 497 L Sbjct: 454 L 454 >gi|11141885 solute carrier family 5 (choline transporter), member 7 [Homo sapiens] Length = 580 Score = 93.6 bits (231), Expect = 5e-19 Identities = 121/486 (24%), Positives = 207/486 (42%), Gaps = 64/486 (13%) Query: 26 ILVIAAYFLLVIGVGLWSMCRT-NRGTVG----GYFLAGRSMVWWPVGASLFASNIGSGH 80 ++ I ++LL++ VG+W+ RT N G+ + GR + G ++ A+ +G G+ Sbjct: 8 LIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGY 67 Query: 81 FVGLA------GTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTAGVITMPQYLRKRFG 134 G A G G A A G+ + ++L G FA + G +TM ++ +G Sbjct: 68 INGTAEAVYVPGYGLAWAQAPIGYSLS----LILGGLFFAKPMRSKGYVTMLDPFQQIYG 123 Query: 135 GRRIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGL 194 +R+ L + +L +F ++ GA I + +++ SVI I +YT+ GGL Sbjct: 124 -KRMGGLLFIPALMGEMFWAAAIFSALGAT-ISVIIDVDMHISVIISALIATLYTLVGGL 181 Query: 195 AALMYTDTVQTFVILGGACILMGYAFHEVG----GYSGLFDKYLGAATSLTVSEDPAVGN 250 ++ YTD VQ F I G I + +A G++ + KY + P +G Sbjct: 182 YSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKY----------QKPWLGT 231 Query: 251 ISSFCYRPRPDSYHLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKSLTHI 310 + S DS+ LL + G +PW Q QR L+ S T+ Sbjct: 232 VDSSEVYSWLDSFLLL---MLGGIPW------------------QAYFQRVLSSSSATYA 270 Query: 311 KAGCILCGYLKLTPMFLMVMPGMISRILYPDEVACVVPEVCRRVCGTEVGCSNIAYPRLV 370 + L + L ++ G I ++ A +P+ TE +++ P ++ Sbjct: 271 QVLSFLAAFGCLVMAIPAILIGAIGASTDWNQTAYGLPDPKT----TEE--ADMILPIVL 324 Query: 371 VKLMPNGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIY-TRLRPRAGDRELLLVGRLW 429 L P + L + AA+MSS S S+S++F +IY R A D+E++ V R+ Sbjct: 325 QYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRI- 383 Query: 430 VVFIVVVSVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFWGL 489 VF+ S + ++ G + V + P + V LFV N GA G Sbjct: 384 TVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQLLCV----LFVKGTNTYGAVAGY 439 Query: 490 IGGLLM 495 + GL + Sbjct: 440 VSGLFL 445 >gi|31881740 solute carrier family 12 (potassium/chloride transporters), member 9 [Homo sapiens] Length = 914 Score = 35.4 bits (80), Expect = 0.17 Identities = 37/122 (30%), Positives = 54/122 (44%), Gaps = 20/122 (16%) Query: 27 LVIAAYFLLVIGVGLWSMCRTNRGTVGG--YFLAGRSM---VWWPVGASLFASNIGSGHF 81 +++ AYF+L + V TN GG YF+ R++ V +G + +N+ G Sbjct: 75 MLLVAYFILALTVLSVCAIATNGAVQGGGAYFMISRTLGPEVGGSIGLMFYLANV-CGCA 133 Query: 82 VGLAGT--------GA----ASGLAVA--GFEWNALFVVLLLGWLFAPVYLTAGVITMPQ 127 V L G GA SGL V G+ WN L+ LLLG + L AG+ Sbjct: 134 VSLLGLVESVLDVFGADATGPSGLRVLPQGYGWNLLYGSLLLGLVGGVCTLGAGLYARAS 193 Query: 128 YL 129 +L Sbjct: 194 FL 195 >gi|21361581 solute carrier family 6 (neurotransmitter transporter, GABA), member 13 [Homo sapiens] Length = 602 Score = 33.5 bits (75), Expect = 0.66 Identities = 30/103 (29%), Positives = 45/103 (43%), Gaps = 11/103 (10%) Query: 360 GCSNIAYPRLVVKLMPNGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGD 419 G + IAYPR VV L + L M+ L + S +D+Y + + Sbjct: 356 GLAFIAYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPHVFRKKNR 415 Query: 420 RELLLVGRLWVVFIVVVSVAWLPVVQAAQGG----QLFDYIQA 458 RE+L++G V F+V ++ +GG QLFDY A Sbjct: 416 REVLILGVSVVSFLV-------GLIMLTEGGMYVFQLFDYYAA 451 >gi|52627158 olfactory receptor, family 6, subfamily N, member 2 [Homo sapiens] Length = 317 Score = 32.0 bits (71), Expect = 1.9 Identities = 27/109 (24%), Positives = 45/109 (41%), Gaps = 7/109 (6%) Query: 138 IRLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAAL 197 +R +L VL L Y+FT + + + AL +Y V L + + YT T + + Sbjct: 23 VRGWLFVLLLLAYLFTICGNMLIFSVIRLDAALHTPMYHFVSVLSFLELWYTAT-TIPKM 81 Query: 198 MYTDTVQTFVILGGACILMGYAFHEVGG------YSGLFDKYLGAATSL 240 + + I C+L Y FH +G + +D+YL L Sbjct: 82 LSNILSEKKTISFAGCLLQTYFFHSLGASECYLLTAMAYDRYLAICRPL 130 >gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens] Length = 364 Score = 31.2 bits (69), Expect = 3.3 Identities = 39/172 (22%), Positives = 71/172 (41%), Gaps = 16/172 (9%) Query: 379 RGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGRLWVVFIV---V 435 +GL+ + A++ + LA T+F M ++TR+ R R ++++ +W + IV + Sbjct: 125 QGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNR---RVVVVIVVIWTMAIVMGAI 181 Query: 436 VSVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFWGLIGGLLM 495 SV W + + SYL A+F L FV V +G + M Sbjct: 182 PSVGWNCICDIENCSNMAPLYS--DSYLV--FWAIFNLVTFVVMVVLYAHIFGYVRQRTM 237 Query: 496 GLARLIPEFSFGSGSCVQPSACPAFLCGVHYLYFAIVLFFCSGLLTLTVSLC 547 ++R SG + L V + A ++ + GL+ L + +C Sbjct: 238 RMSR------HSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVC 283 >gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens] Length = 364 Score = 31.2 bits (69), Expect = 3.3 Identities = 39/172 (22%), Positives = 71/172 (41%), Gaps = 16/172 (9%) Query: 379 RGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGRLWVVFIV---V 435 +GL+ + A++ + LA T+F M ++TR+ R R ++++ +W + IV + Sbjct: 125 QGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNR---RVVVVIVVIWTMAIVMGAI 181 Query: 436 VSVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFWGLIGGLLM 495 SV W + + SYL A+F L FV V +G + M Sbjct: 182 PSVGWNCICDIENCSNMAPLYS--DSYLV--FWAIFNLVTFVVMVVLYAHIFGYVRQRTM 237 Query: 496 GLARLIPEFSFGSGSCVQPSACPAFLCGVHYLYFAIVLFFCSGLLTLTVSLC 547 ++R SG + L V + A ++ + GL+ L + +C Sbjct: 238 RMSR------HSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVC 283 >gi|149274607 solute carrier family 25, member 41 [Homo sapiens] Length = 370 Score = 31.2 bits (69), Expect = 3.3 Identities = 28/99 (28%), Positives = 46/99 (46%), Gaps = 6/99 (6%) Query: 530 AIVLFFCSGLLTLTVSLC-TAPIPRKHLHRLVFSLRHSKEER-EDLDADEQQGSSLPVQN 587 A+ F SG + VS TAP+ R ++ V+S + + L + Q+G + Sbjct: 91 ALWKFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNFTNLLGGLQSMVQEGGFRSLWR 150 Query: 588 GCPESAMEMNEPQAPAPSLFRQCLLWFCGMSRGGVGSPP 626 G + +++ A S+F QC +FCG+ GSPP Sbjct: 151 GNGINVLKIAPEYAIKFSVFEQCKNYFCGIQ----GSPP 185 >gi|7657587 solute carrier family 6 (neurotransmitter transporter, GABA), member 11 [Homo sapiens] Length = 632 Score = 30.8 bits (68), Expect = 4.2 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 9/113 (7%) Query: 360 GCSNIAYPRLVVKLMPNGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGD 419 G + IAYP+ V + + L + +ML L + S +D+Y ++ R Sbjct: 376 GLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYR 435 Query: 420 RELLLVGRLWVVFIVVVSVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFV 472 RELL++ + V+S +L +V +GG Q SY A + +FV Sbjct: 436 RELLILA------LSVISY-FLGLVMLTEGGMYI--FQLFDSYAASGMCLLFV 479 >gi|239757591 PREDICTED: hypothetical protein XP_002345493 [Homo sapiens] Length = 598 Score = 30.0 bits (66), Expect = 7.2 Identities = 24/63 (38%), Positives = 29/63 (46%), Gaps = 16/63 (25%) Query: 588 GCPESAMEMNEPQAPA---PSLFRQCLLWFCGMS---------RGGV-GSPPPLTQEEAA 634 GC ++ P++PA PS F L CG S RGGV G PPP + E Sbjct: 486 GCRPPRLKSERPRSPAHPSPSAFPALL---CGDSCCFGGDAKPRGGVSGQPPPSNEPEKP 542 Query: 635 AAA 637 AAA Sbjct: 543 AAA 545 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.327 0.141 0.447 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,499,961 Number of Sequences: 37866 Number of extensions: 1184359 Number of successful extensions: 3978 Number of sequences better than 10.0: 22 Number of HSP's better than 10.0 without gapping: 14 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 3924 Number of HSP's gapped (non-prelim): 29 length of query: 672 length of database: 18,247,518 effective HSP length: 109 effective length of query: 563 effective length of database: 14,120,124 effective search space: 7949629812 effective search space used: 7949629812 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.