Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 4506303
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506303 protein tyrosine phosphatase, receptor type, A
isoform 1 precursor [Homo sapiens]
(802 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506303 protein tyrosine phosphatase, receptor type, A isofor... 1630 0.0
gi|18450371 protein tyrosine phosphatase, receptor type, A isofo... 1604 0.0
gi|18450369 protein tyrosine phosphatase, receptor type, A isofo... 1604 0.0
gi|5729993 protein tyrosine phosphatase, receptor type, E isofor... 939 0.0
gi|18860859 protein tyrosine phosphatase, receptor type, E isofo... 924 0.0
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 609 e-174
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 609 e-174
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 602 e-172
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 602 e-172
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 602 e-172
gi|18860894 protein tyrosine phosphatase, receptor type, D isofo... 602 e-172
gi|104487002 protein tyrosine phosphatase, receptor type, D isof... 598 e-171
gi|104487611 protein tyrosine phosphatase, receptor type, sigma ... 592 e-169
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ... 592 e-169
gi|104487295 protein tyrosine phosphatase, receptor type, sigma ... 592 e-169
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ... 588 e-168
gi|18641364 protein tyrosine phosphatase, receptor type, C isofo... 471 e-132
gi|18641347 protein tyrosine phosphatase, receptor type, C isofo... 471 e-132
gi|18641362 protein tyrosine phosphatase, receptor type, C isofo... 471 e-132
gi|18860902 protein tyrosine phosphatase, receptor type, K isofo... 441 e-123
gi|157419150 protein tyrosine phosphatase, receptor type, M isof... 440 e-123
gi|157419152 protein tyrosine phosphatase, receptor type, M isof... 440 e-123
gi|208431815 protein tyrosine phosphatase, receptor type, K isof... 435 e-122
gi|148539860 protein tyrosine phosphatase, receptor type, T isof... 434 e-121
gi|148539858 protein tyrosine phosphatase, receptor type, T isof... 434 e-121
gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1 p... 405 e-113
gi|110735404 protein tyrosine phosphatase, receptor type, U isof... 404 e-112
gi|110735402 protein tyrosine phosphatase, receptor type, U isof... 404 e-112
gi|194097398 protein tyrosine phosphatase, receptor type, G prec... 403 e-112
gi|110735406 protein tyrosine phosphatase, receptor type, U isof... 398 e-110
>gi|4506303 protein tyrosine phosphatase, receptor type, A isoform 1
precursor [Homo sapiens]
Length = 802
Score = 1630 bits (4221), Expect = 0.0
Identities = 802/802 (100%), Positives = 802/802 (100%)
Query: 1 MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLS 60
MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLS
Sbjct: 1 MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLS 60
Query: 61 VAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEP 120
VAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEP
Sbjct: 61 VAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEP 120
Query: 121 WEGNSSTAATTPETFPPSGNSDSKDRRDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKY 180
WEGNSSTAATTPETFPPSGNSDSKDRRDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKY
Sbjct: 121 WEGNSSTAATTPETFPPSGNSDSKDRRDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKY 180
Query: 181 KQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKL 240
KQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKL
Sbjct: 181 KQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKL 240
Query: 241 FREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASF 300
FREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASF
Sbjct: 241 FREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASF 300
Query: 301 INGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCW 360
INGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCW
Sbjct: 301 INGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCW 360
Query: 361 TYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGM 420
TYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGM
Sbjct: 361 TYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGM 420
Query: 421 LKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ 480
LKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ
Sbjct: 421 LKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ 480
Query: 481 RCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL 540
RCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL
Sbjct: 481 RCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL 540
Query: 541 TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQK 600
TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQK
Sbjct: 541 TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQK 600
Query: 601 DSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITV 660
DSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITV
Sbjct: 601 DSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITV 660
Query: 661 ELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQ 720
ELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQ
Sbjct: 661 ELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQ 720
Query: 721 QQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ 780
QQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ
Sbjct: 721 QQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ 780
Query: 781 YEFCYKVVQEYIDAFSDYANFK 802
YEFCYKVVQEYIDAFSDYANFK
Sbjct: 781 YEFCYKVVQEYIDAFSDYANFK 802
>gi|18450371 protein tyrosine phosphatase, receptor type, A isoform
2 precursor [Homo sapiens]
Length = 793
Score = 1604 bits (4154), Expect = 0.0
Identities = 793/802 (98%), Positives = 793/802 (98%), Gaps = 9/802 (1%)
Query: 1 MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLS 60
MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLS
Sbjct: 1 MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLS 60
Query: 61 VAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEP 120
VAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEP
Sbjct: 61 VAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEP 120
Query: 121 WEGNSSTAATTPETFPPSGNSDSKDRRDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKY 180
WEGNSSTAATTPETFPPS DETPIIAVMVALSSLLVIVFIIIVLYMLRFKKY
Sbjct: 121 WEGNSSTAATTPETFPPS---------DETPIIAVMVALSSLLVIVFIIIVLYMLRFKKY 171
Query: 181 KQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKL 240
KQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKL
Sbjct: 172 KQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKL 231
Query: 241 FREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASF 300
FREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASF
Sbjct: 232 FREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASF 291
Query: 301 INGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCW 360
INGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCW
Sbjct: 292 INGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCW 351
Query: 361 TYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGM 420
TYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGM
Sbjct: 352 TYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGM 411
Query: 421 LKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ 480
LKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ
Sbjct: 412 LKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ 471
Query: 481 RCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL 540
RCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL
Sbjct: 472 RCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL 531
Query: 541 TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQK 600
TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQK
Sbjct: 532 TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQK 591
Query: 601 DSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITV 660
DSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITV
Sbjct: 592 DSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITV 651
Query: 661 ELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQ 720
ELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQ
Sbjct: 652 ELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQ 711
Query: 721 QQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ 780
QQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ
Sbjct: 712 QQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ 771
Query: 781 YEFCYKVVQEYIDAFSDYANFK 802
YEFCYKVVQEYIDAFSDYANFK
Sbjct: 772 YEFCYKVVQEYIDAFSDYANFK 793
>gi|18450369 protein tyrosine phosphatase, receptor type, A isoform
2 precursor [Homo sapiens]
Length = 793
Score = 1604 bits (4154), Expect = 0.0
Identities = 793/802 (98%), Positives = 793/802 (98%), Gaps = 9/802 (1%)
Query: 1 MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLS 60
MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLS
Sbjct: 1 MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLS 60
Query: 61 VAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEP 120
VAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEP
Sbjct: 61 VAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEP 120
Query: 121 WEGNSSTAATTPETFPPSGNSDSKDRRDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKY 180
WEGNSSTAATTPETFPPS DETPIIAVMVALSSLLVIVFIIIVLYMLRFKKY
Sbjct: 121 WEGNSSTAATTPETFPPS---------DETPIIAVMVALSSLLVIVFIIIVLYMLRFKKY 171
Query: 181 KQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKL 240
KQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKL
Sbjct: 172 KQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKL 231
Query: 241 FREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASF 300
FREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASF
Sbjct: 232 FREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASF 291
Query: 301 INGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCW 360
INGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCW
Sbjct: 292 INGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCW 351
Query: 361 TYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGM 420
TYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGM
Sbjct: 352 TYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGM 411
Query: 421 LKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ 480
LKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ
Sbjct: 412 LKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ 471
Query: 481 RCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL 540
RCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL
Sbjct: 472 RCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL 531
Query: 541 TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQK 600
TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQK
Sbjct: 532 TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQK 591
Query: 601 DSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITV 660
DSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITV
Sbjct: 592 DSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITV 651
Query: 661 ELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQ 720
ELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQ
Sbjct: 652 ELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQ 711
Query: 721 QQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ 780
QQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ
Sbjct: 712 QQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ 771
Query: 781 YEFCYKVVQEYIDAFSDYANFK 802
YEFCYKVVQEYIDAFSDYANFK
Sbjct: 772 YEFCYKVVQEYIDAFSDYANFK 793
>gi|5729993 protein tyrosine phosphatase, receptor type, E isoform 1
precursor [Homo sapiens]
Length = 700
Score = 939 bits (2428), Expect = 0.0
Identities = 465/686 (67%), Positives = 560/686 (81%), Gaps = 13/686 (1%)
Query: 123 GNSSTAATTPETFPPSGNSDSKDRRDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQ 182
GN +TA + ET SG D + P++A ++ L LL+++ +++ Y RF+K ++
Sbjct: 22 GNETTADSN-ETTTTSGPPDPGASQ---PLLAWLL-LPLLLLLLVLLLAAYFFRFRKQRK 76
Query: 183 AGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFR 242
A ++ ++ NG E+ E Q V LL+RSPS +KY P+PV+ LEEEI R ADD K FR
Sbjct: 77 AVVSTSDKKMPNGILEEQEQQRVMLLSRSPSGPKKYFPIPVEHLEEEIRIRSADDCKQFR 136
Query: 243 EEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFIN 302
EEFN+LP+ IQ T E A+KEEN+EKNRY NILP DHSRV L+ ++G+P SDYINAS+I+
Sbjct: 137 EEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHSRVILSQLDGIPCSDYINASYID 196
Query: 303 GYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTY 362
GY+EKNKFIAAQGPK+ETVNDFWRM+WEQ +ATIVM+TNLKERKE KC QYWPDQGCWTY
Sbjct: 197 GYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERKEEKCHQYWPDQGCWTY 256
Query: 363 GNIRVSVEDVTVLVDYTVRKFCIQ-QVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGML 421
GNIRV VED VLVDYT+RKFCIQ Q+ D K RL++Q HFTSWPDFGVPFTPIGML
Sbjct: 257 GNIRVCVEDCVVLVDYTIRKFCIQPQLPD--GCKAPRLVSQLHFTSWPDFGVPFTPIGML 314
Query: 422 KFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQR 481
KFLKKVK NP +AG IVVHCSAGVGRTGTF+VIDAM+ MMH E+KVDV+ FVSRIR QR
Sbjct: 315 KFLKKVKTLNPVHAGPIVVHCSAGVGRTGTFIVIDAMMAMMHAEQKVDVFEFVSRIRNQR 374
Query: 482 CQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLT 541
QMVQTDMQY FIYQALLE+YLYGDTEL+V+SLE HLQ ++ GLEEEF+KLT
Sbjct: 375 PQMVQTDMQYTFIYQALLEYYLYGDTELDVSSLEKHLQTMHGTTTHFDKIGLEEEFRKLT 434
Query: 542 SIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKD 601
+++I + MRTGNLPANMKK RV+QIIPY+FNRVI+ +KRG+E TDY+NASFIDGYRQKD
Sbjct: 435 NVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVILSMKRGQEYTDYINASFIDGYRQKD 494
Query: 602 SYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVE 661
+IA+QGPL HT+EDFWRMIWEWKS +IVMLTE++ER Q+KC QYWP++G V++G+IT+E
Sbjct: 495 YFIATQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQEREQDKCYQYWPTEGSVTHGEITIE 554
Query: 662 LKKEEECESYTVRDLLVT-----NTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAV 716
+K + E+ ++RD LVT +E + R +RQFHFHGWPE+GIP++GKGMI +IAAV
Sbjct: 555 IKNDTLSEAISIRDFLVTLNQPQARQEEQVRVVRQFHFHGWPEIGIPAEGKGMIDLIAAV 614
Query: 717 QKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQ 776
QKQQQQ+GNHPITVHCSAGAGRTGTF ALS +LERVKAEG+LDVFQ VKSLRLQRPHMVQ
Sbjct: 615 QKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAEGLLDVFQAVKSLRLQRPHMVQ 674
Query: 777 TLEQYEFCYKVVQEYIDAFSDYANFK 802
TLEQYEFCYKVVQ++ID FSDYANFK
Sbjct: 675 TLEQYEFCYKVVQDFIDIFSDYANFK 700
>gi|18860859 protein tyrosine phosphatase, receptor type, E isoform
2 [Homo sapiens]
Length = 642
Score = 924 bits (2387), Expect = 0.0
Identities = 449/632 (71%), Positives = 531/632 (84%), Gaps = 8/632 (1%)
Query: 177 FKKYKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMAD 236
F+K ++A ++ ++ NG E+ E Q V LL+RSPS +KY P+PV+ LEEEI R AD
Sbjct: 13 FRKQRKAVVSTSDKKMPNGILEEQEQQRVMLLSRSPSGPKKYFPIPVEHLEEEIRIRSAD 72
Query: 237 DNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYI 296
D K FREEFN+LP+ IQ T E A+KEEN+EKNRY NILP DHSRV L+ ++G+P SDYI
Sbjct: 73 DCKQFREEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHSRVILSQLDGIPCSDYI 132
Query: 297 NASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPD 356
NAS+I+GY+EKNKFIAAQGPK+ETVNDFWRM+WEQ +ATIVM+TNLKERKE KC QYWPD
Sbjct: 133 NASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERKEEKCHQYWPD 192
Query: 357 QGCWTYGNIRVSVEDVTVLVDYTVRKFCIQ-QVGDMTNRKPQRLITQFHFTSWPDFGVPF 415
QGCWTYGNIRV VED VLVDYT+RKFCIQ Q+ D K RL++Q HFTSWPDFGVPF
Sbjct: 193 QGCWTYGNIRVCVEDCVVLVDYTIRKFCIQPQLPD--GCKAPRLVSQLHFTSWPDFGVPF 250
Query: 416 TPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVS 475
TPIGMLKFLKKVK NP +AG IVVHCSAGVGRTGTF+VIDAM+ MMH E+KVDV+ FVS
Sbjct: 251 TPIGMLKFLKKVKTLNPVHAGPIVVHCSAGVGRTGTFIVIDAMMAMMHAEQKVDVFEFVS 310
Query: 476 RIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEE 535
RIR QR QMVQTDMQY FIYQALLE+YLYGDTEL+V+SLE HLQ ++ GLEE
Sbjct: 311 RIRNQRPQMVQTDMQYTFIYQALLEYYLYGDTELDVSSLEKHLQTMHGTTTHFDKIGLEE 370
Query: 536 EFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFID 595
EF+KLT+++I + MRTGNLPANMKK RV+QIIPY+FNRVI+ +KRG+E TDY+NASFID
Sbjct: 371 EFRKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVILSMKRGQEYTDYINASFID 430
Query: 596 GYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSY 655
GYRQKD +IA+QGPL HT+EDFWRMIWEWKS +IVMLTE++ER Q+KC QYWP++G V++
Sbjct: 431 GYRQKDYFIATQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQEREQDKCYQYWPTEGSVTH 490
Query: 656 GDITVELKKEEECESYTVRDLLVT-----NTRENKSRQIRQFHFHGWPEVGIPSDGKGMI 710
G+IT+E+K + E+ ++RD LVT +E + R +RQFHFHGWPE+GIP++GKGMI
Sbjct: 491 GEITIEIKNDTLSEAISIRDFLVTLNQPQARQEEQVRVVRQFHFHGWPEIGIPAEGKGMI 550
Query: 711 SIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQ 770
+IAAVQKQQQQ+GNHPITVHCSAGAGRTGTF ALS +LERVKAEG+LDVFQ VKSLRLQ
Sbjct: 551 DLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAEGLLDVFQAVKSLRLQ 610
Query: 771 RPHMVQTLEQYEFCYKVVQEYIDAFSDYANFK 802
RPHMVQTLEQYEFCYKVVQ++ID FSDYANFK
Sbjct: 611 RPHMVQTLEQYEFCYKVVQDFIDIFSDYANFK 642
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
precursor [Homo sapiens]
Length = 1907
Score = 609 bits (1570), Expect = e-174
Identities = 314/644 (48%), Positives = 421/644 (65%), Gaps = 12/644 (1%)
Query: 162 LLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDV-----EPQSVPLLARSPSTNR 216
L VI+ I+IV+ +L FK+ K+ S S+ S G + + +P + L R
Sbjct: 1269 LAVILIILIVIAILLFKR-KRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPGMR 1327
Query: 217 KYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILP 276
+PP+P+ L + I R A+D F +E+ ++ Q T E ++ E NK KNRY N++
Sbjct: 1328 DHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQ-QFTWENSNLEVNKPKNRYANVIA 1386
Query: 277 YDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATI 336
YDHSRV LT ++GVP SDYINA++I+GY+++N +IA QGP ET+ DFWRM+WEQ TAT+
Sbjct: 1387 YDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATV 1446
Query: 337 VMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKP 396
VM+T L+E+ KC QYWP +G T G I+V++ D L YTVR F + + G R+
Sbjct: 1447 VMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRE- 1505
Query: 397 QRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVID 456
+ QF F +WPD GVP P +L FL++VKACNP AG +VVHCSAGVGRTG F+VID
Sbjct: 1506 ---LRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVID 1562
Query: 457 AMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLET 516
AML+ M E+ VD+YG V+ +R+QR MVQT+ QYVFI++ALLE G TE+ +L
Sbjct: 1563 AMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYA 1622
Query: 517 HLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVI 576
H+QK+ PG S +E EFK L S K + + NLP N KNR++ I+PYE RV
Sbjct: 1623 HIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVC 1682
Query: 577 IPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELE 636
+ RG E +DY+NASF+DGYRQ+ +YIA+QGPL + EDFWRM+WE S IVMLT+L
Sbjct: 1683 LQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLR 1742
Query: 637 ERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHG 696
E G+EKC QYWP++ Y V+ E Y +R+ VT+ R+ +SR IRQF F
Sbjct: 1743 EMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTD 1802
Query: 697 WPEVGIPSDGKGMISIIAAVQKQQQQSG-NHPITVHCSAGAGRTGTFCALSTVLERVKAE 755
WPE G+P G+G I I V K ++Q G + PITVHCSAG GRTG F LS VLER++ E
Sbjct: 1803 WPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYE 1862
Query: 756 GILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAFSDYA 799
G++D+FQTVK+LR QRP MVQT +QY+ CY+ EY+ +F YA
Sbjct: 1863 GVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYA 1906
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
precursor [Homo sapiens]
Length = 1898
Score = 609 bits (1570), Expect = e-174
Identities = 314/644 (48%), Positives = 421/644 (65%), Gaps = 12/644 (1%)
Query: 162 LLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDV-----EPQSVPLLARSPSTNR 216
L VI+ I+IV+ +L FK+ K+ S S+ S G + + +P + L R
Sbjct: 1260 LAVILIILIVIAILLFKR-KRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPGMR 1318
Query: 217 KYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILP 276
+PP+P+ L + I R A+D F +E+ ++ Q T E ++ E NK KNRY N++
Sbjct: 1319 DHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQ-QFTWENSNLEVNKPKNRYANVIA 1377
Query: 277 YDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATI 336
YDHSRV LT ++GVP SDYINA++I+GY+++N +IA QGP ET+ DFWRM+WEQ TAT+
Sbjct: 1378 YDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATV 1437
Query: 337 VMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKP 396
VM+T L+E+ KC QYWP +G T G I+V++ D L YTVR F + + G R+
Sbjct: 1438 VMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRE- 1496
Query: 397 QRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVID 456
+ QF F +WPD GVP P +L FL++VKACNP AG +VVHCSAGVGRTG F+VID
Sbjct: 1497 ---LRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVID 1553
Query: 457 AMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLET 516
AML+ M E+ VD+YG V+ +R+QR MVQT+ QYVFI++ALLE G TE+ +L
Sbjct: 1554 AMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYA 1613
Query: 517 HLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVI 576
H+QK+ PG S +E EFK L S K + + NLP N KNR++ I+PYE RV
Sbjct: 1614 HIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVC 1673
Query: 577 IPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELE 636
+ RG E +DY+NASF+DGYRQ+ +YIA+QGPL + EDFWRM+WE S IVMLT+L
Sbjct: 1674 LQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLR 1733
Query: 637 ERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHG 696
E G+EKC QYWP++ Y V+ E Y +R+ VT+ R+ +SR IRQF F
Sbjct: 1734 EMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTD 1793
Query: 697 WPEVGIPSDGKGMISIIAAVQKQQQQSG-NHPITVHCSAGAGRTGTFCALSTVLERVKAE 755
WPE G+P G+G I I V K ++Q G + PITVHCSAG GRTG F LS VLER++ E
Sbjct: 1794 WPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYE 1853
Query: 756 GILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAFSDYA 799
G++D+FQTVK+LR QRP MVQT +QY+ CY+ EY+ +F YA
Sbjct: 1854 GVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYA 1897
>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
precursor [Homo sapiens]
Length = 1912
Score = 602 bits (1552), Expect = e-172
Identities = 312/681 (45%), Positives = 431/681 (63%), Gaps = 13/681 (1%)
Query: 125 SSTAATTPETFPP-SGNSDSKDRRDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQA 183
S AT+P + P S + D + DE ++ + +L +VFII ++ + K K+A
Sbjct: 1238 SKMYATSPYSDPVVSMDLDPQPITDEEE--GLIWVVGPVLAVVFIICIVIAILLYKRKRA 1295
Query: 184 GSHSNSFRLSNGRT----EDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNK 239
S S + N + +P + L +PP+P+ +L + I R A+DN
Sbjct: 1296 ESDSRKSSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNL 1355
Query: 240 LFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINAS 299
F +E+ ++ Q T E ++ E NK KNRY N++ YDHSRV L+ +EG+P SDY+NA+
Sbjct: 1356 KFSQEYESIDPGQ-QFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNAN 1414
Query: 300 FINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGC 359
+I+GY+++N +IA QG ET DFWRMIWEQ +AT+VM+T L+ER KC QYWP +G
Sbjct: 1415 YIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGT 1474
Query: 360 WTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIG 419
T+G ++V++ D L Y VR F + + G R+ + QF FT+WPD GVP P
Sbjct: 1475 ETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKRE----VRQFQFTAWPDHGVPEHPTP 1530
Query: 420 MLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRA 479
L FL++VK CNP AG +VVHCSAGVGRTG F+VIDAML+ + E+ VD+YG V+ +RA
Sbjct: 1531 FLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRA 1590
Query: 480 QRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKK 539
QR MVQT+ QY+FI+ ALLE G+TE+ +L ++QK+ G + G+E EFK+
Sbjct: 1591 QRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKR 1650
Query: 540 LTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQ 599
L S K + + NLP N KNR++ I+PYE RV + RG E +DY+NASFIDGYRQ
Sbjct: 1651 LASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQ 1710
Query: 600 KDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDIT 659
+ +YIA+QGPL T EDFWRM+WE S +VMLT+L E G+EKC QYWP++ Y
Sbjct: 1711 QKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFV 1770
Query: 660 VELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQ 719
V+ E Y +R+ VT+ R+ +SR +RQF F WPE G+P G+G I I V K
Sbjct: 1771 VDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKT 1830
Query: 720 QQQSG-NHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTL 778
++Q G + PI+VHCSAG GRTG F LS VLER++ EG++D+FQTVK LR QRP MVQT
Sbjct: 1831 KEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTE 1890
Query: 779 EQYEFCYKVVQEYIDAFSDYA 799
+QY+F Y+ EY+ +F YA
Sbjct: 1891 DQYQFSYRAALEYLGSFDHYA 1911
>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform 2
precursor [Homo sapiens]
Length = 1899
Score = 602 bits (1552), Expect = e-172
Identities = 312/681 (45%), Positives = 431/681 (63%), Gaps = 13/681 (1%)
Query: 125 SSTAATTPETFPP-SGNSDSKDRRDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQA 183
S AT+P + P S + D + DE ++ + +L +VFII ++ + K K+A
Sbjct: 1225 SKMYATSPYSDPVVSMDLDPQPITDEEE--GLIWVVGPVLAVVFIICIVIAILLYKRKRA 1282
Query: 184 GSHSNSFRLSNGRT----EDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNK 239
S S + N + +P + L +PP+P+ +L + I R A+DN
Sbjct: 1283 ESDSRKSSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNL 1342
Query: 240 LFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINAS 299
F +E+ ++ Q T E ++ E NK KNRY N++ YDHSRV L+ +EG+P SDY+NA+
Sbjct: 1343 KFSQEYESIDPGQ-QFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNAN 1401
Query: 300 FINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGC 359
+I+GY+++N +IA QG ET DFWRMIWEQ +AT+VM+T L+ER KC QYWP +G
Sbjct: 1402 YIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGT 1461
Query: 360 WTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIG 419
T+G ++V++ D L Y VR F + + G R+ + QF FT+WPD GVP P
Sbjct: 1462 ETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKRE----VRQFQFTAWPDHGVPEHPTP 1517
Query: 420 MLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRA 479
L FL++VK CNP AG +VVHCSAGVGRTG F+VIDAML+ + E+ VD+YG V+ +RA
Sbjct: 1518 FLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRA 1577
Query: 480 QRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKK 539
QR MVQT+ QY+FI+ ALLE G+TE+ +L ++QK+ G + G+E EFK+
Sbjct: 1578 QRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKR 1637
Query: 540 LTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQ 599
L S K + + NLP N KNR++ I+PYE RV + RG E +DY+NASFIDGYRQ
Sbjct: 1638 LASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQ 1697
Query: 600 KDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDIT 659
+ +YIA+QGPL T EDFWRM+WE S +VMLT+L E G+EKC QYWP++ Y
Sbjct: 1698 QKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFV 1757
Query: 660 VELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQ 719
V+ E Y +R+ VT+ R+ +SR +RQF F WPE G+P G+G I I V K
Sbjct: 1758 VDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKT 1817
Query: 720 QQQSG-NHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTL 778
++Q G + PI+VHCSAG GRTG F LS VLER++ EG++D+FQTVK LR QRP MVQT
Sbjct: 1818 KEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTE 1877
Query: 779 EQYEFCYKVVQEYIDAFSDYA 799
+QY+F Y+ EY+ +F YA
Sbjct: 1878 DQYQFSYRAALEYLGSFDHYA 1898
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
precursor [Homo sapiens]
Length = 1903
Score = 602 bits (1552), Expect = e-172
Identities = 312/681 (45%), Positives = 431/681 (63%), Gaps = 13/681 (1%)
Query: 125 SSTAATTPETFPP-SGNSDSKDRRDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQA 183
S AT+P + P S + D + DE ++ + +L +VFII ++ + K K+A
Sbjct: 1229 SKMYATSPYSDPVVSMDLDPQPITDEEE--GLIWVVGPVLAVVFIICIVIAILLYKRKRA 1286
Query: 184 GSHSNSFRLSNGRT----EDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNK 239
S S + N + +P + L +PP+P+ +L + I R A+DN
Sbjct: 1287 ESDSRKSSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNL 1346
Query: 240 LFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINAS 299
F +E+ ++ Q T E ++ E NK KNRY N++ YDHSRV L+ +EG+P SDY+NA+
Sbjct: 1347 KFSQEYESIDPGQ-QFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNAN 1405
Query: 300 FINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGC 359
+I+GY+++N +IA QG ET DFWRMIWEQ +AT+VM+T L+ER KC QYWP +G
Sbjct: 1406 YIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGT 1465
Query: 360 WTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIG 419
T+G ++V++ D L Y VR F + + G R+ + QF FT+WPD GVP P
Sbjct: 1466 ETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKRE----VRQFQFTAWPDHGVPEHPTP 1521
Query: 420 MLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRA 479
L FL++VK CNP AG +VVHCSAGVGRTG F+VIDAML+ + E+ VD+YG V+ +RA
Sbjct: 1522 FLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRA 1581
Query: 480 QRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKK 539
QR MVQT+ QY+FI+ ALLE G+TE+ +L ++QK+ G + G+E EFK+
Sbjct: 1582 QRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKR 1641
Query: 540 LTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQ 599
L S K + + NLP N KNR++ I+PYE RV + RG E +DY+NASFIDGYRQ
Sbjct: 1642 LASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQ 1701
Query: 600 KDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDIT 659
+ +YIA+QGPL T EDFWRM+WE S +VMLT+L E G+EKC QYWP++ Y
Sbjct: 1702 QKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFV 1761
Query: 660 VELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQ 719
V+ E Y +R+ VT+ R+ +SR +RQF F WPE G+P G+G I I V K
Sbjct: 1762 VDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKT 1821
Query: 720 QQQSG-NHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTL 778
++Q G + PI+VHCSAG GRTG F LS VLER++ EG++D+FQTVK LR QRP MVQT
Sbjct: 1822 KEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTE 1881
Query: 779 EQYEFCYKVVQEYIDAFSDYA 799
+QY+F Y+ EY+ +F YA
Sbjct: 1882 DQYQFSYRAALEYLGSFDHYA 1902
>gi|18860894 protein tyrosine phosphatase, receptor type, D isoform 4
precursor [Homo sapiens]
Length = 1501
Score = 602 bits (1552), Expect = e-172
Identities = 312/681 (45%), Positives = 431/681 (63%), Gaps = 13/681 (1%)
Query: 125 SSTAATTPETFPP-SGNSDSKDRRDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQA 183
S AT+P + P S + D + DE ++ + +L +VFII ++ + K K+A
Sbjct: 827 SKMYATSPYSDPVVSMDLDPQPITDEEE--GLIWVVGPVLAVVFIICIVIAILLYKRKRA 884
Query: 184 GSHSNSFRLSNGRT----EDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNK 239
S S + N + +P + L +PP+P+ +L + I R A+DN
Sbjct: 885 ESDSRKSSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNL 944
Query: 240 LFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINAS 299
F +E+ ++ Q T E ++ E NK KNRY N++ YDHSRV L+ +EG+P SDY+NA+
Sbjct: 945 KFSQEYESIDPGQ-QFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNAN 1003
Query: 300 FINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGC 359
+I+GY+++N +IA QG ET DFWRMIWEQ +AT+VM+T L+ER KC QYWP +G
Sbjct: 1004 YIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGT 1063
Query: 360 WTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIG 419
T+G ++V++ D L Y VR F + + G R+ + QF FT+WPD GVP P
Sbjct: 1064 ETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKRE----VRQFQFTAWPDHGVPEHPTP 1119
Query: 420 MLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRA 479
L FL++VK CNP AG +VVHCSAGVGRTG F+VIDAML+ + E+ VD+YG V+ +RA
Sbjct: 1120 FLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRA 1179
Query: 480 QRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKK 539
QR MVQT+ QY+FI+ ALLE G+TE+ +L ++QK+ G + G+E EFK+
Sbjct: 1180 QRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKR 1239
Query: 540 LTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQ 599
L S K + + NLP N KNR++ I+PYE RV + RG E +DY+NASFIDGYRQ
Sbjct: 1240 LASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQ 1299
Query: 600 KDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDIT 659
+ +YIA+QGPL T EDFWRM+WE S +VMLT+L E G+EKC QYWP++ Y
Sbjct: 1300 QKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFV 1359
Query: 660 VELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQ 719
V+ E Y +R+ VT+ R+ +SR +RQF F WPE G+P G+G I I V K
Sbjct: 1360 VDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKT 1419
Query: 720 QQQSG-NHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTL 778
++Q G + PI+VHCSAG GRTG F LS VLER++ EG++D+FQTVK LR QRP MVQT
Sbjct: 1420 KEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTE 1479
Query: 779 EQYEFCYKVVQEYIDAFSDYA 799
+QY+F Y+ EY+ +F YA
Sbjct: 1480 DQYQFSYRAALEYLGSFDHYA 1500
>gi|104487002 protein tyrosine phosphatase, receptor type, D isoform 5
precursor [Homo sapiens]
Length = 1502
Score = 598 bits (1541), Expect = e-171
Identities = 315/685 (45%), Positives = 434/685 (63%), Gaps = 17/685 (2%)
Query: 125 SSTAATTPETFPP-SGNSDSKDRRDETPIIAVMVALSSLLVIVFII-IVLYMLRFKKY-- 180
S AT+P + P S + D + DE ++ + +L +VFII IV+ +L +K
Sbjct: 824 SKMYATSPYSDPVVSMDLDPQPITDEEE--GLIWVVGPVLAVVFIICIVIAILLYKSKPD 881
Query: 181 -KQAGSHSNSFRLSNGRT----EDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMA 235
K+A S S + N + +P + L +PP+P+ +L + I R A
Sbjct: 882 RKRAESDSRKSSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKA 941
Query: 236 DDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDY 295
+DN F +E+ ++ Q T E ++ E NK KNRY N++ YDHSRV L+ +EG+P SDY
Sbjct: 942 NDNLKFSQEYESIDPGQ-QFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDY 1000
Query: 296 INASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWP 355
+NA++I+GY+++N +IA QG ET DFWRMIWEQ +AT+VM+T L+ER KC QYWP
Sbjct: 1001 VNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWP 1060
Query: 356 DQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPF 415
+G T+G ++V++ D L Y VR F + + G R+ + QF FT+WPD GVP
Sbjct: 1061 SRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKRE----VRQFQFTAWPDHGVPE 1116
Query: 416 TPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVS 475
P L FL++VK CNP AG +VVHCSAGVGRTG F+VIDAML+ + E+ VD+YG V+
Sbjct: 1117 HPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVT 1176
Query: 476 RIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEE 535
+RAQR MVQT+ QY+FI+ ALLE G+TE+ +L ++QK+ G + G+E
Sbjct: 1177 LMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMEL 1236
Query: 536 EFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFID 595
EFK+L S K + + NLP N KNR++ I+PYE RV + RG E +DY+NASFID
Sbjct: 1237 EFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFID 1296
Query: 596 GYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSY 655
GYRQ+ +YIA+QGPL T EDFWRM+WE S +VMLT+L E G+EKC QYWP++ Y
Sbjct: 1297 GYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARY 1356
Query: 656 GDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAA 715
V+ E Y +R+ VT+ R+ +SR +RQF F WPE G+P G+G I I
Sbjct: 1357 QYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQ 1416
Query: 716 VQKQQQQSG-NHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHM 774
V K ++Q G + PI+VHCSAG GRTG F LS VLER++ EG++D+FQTVK LR QRP M
Sbjct: 1417 VHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAM 1476
Query: 775 VQTLEQYEFCYKVVQEYIDAFSDYA 799
VQT +QY+F Y+ EY+ +F YA
Sbjct: 1477 VQTEDQYQFSYRAALEYLGSFDHYA 1501
>gi|104487611 protein tyrosine phosphatase, receptor type, sigma
isoform 4 precursor [Homo sapiens]
Length = 1505
Score = 592 bits (1525), Expect = e-169
Identities = 312/682 (45%), Positives = 426/682 (62%), Gaps = 22/682 (3%)
Query: 134 TFPPSGNSD--SKDRRDETPII----AVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHS 187
TF S SD D D PI+ ++ + +L +VFII ++ + K K
Sbjct: 829 TFAASPFSDPFQLDNPDPQPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRK 888
Query: 188 NS-----FRLSNGRTEDVEPQSVPLLAR----SPSTNRKYPPLPVDKLEEEINRRMADDN 238
+S L+N P+ + R +P +PP+P+ + E R A+D+
Sbjct: 889 DSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPGM-LSHPPIPIADMAEHTERLKANDS 947
Query: 239 KLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINA 298
+E+ ++ Q T E ++ E NK KNRY N++ YDHSRV L P+EG+ SDYINA
Sbjct: 948 LKLSQEYESIDPGQ-QFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINA 1006
Query: 299 SFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQG 358
++++GY+ +N +IA QGP ET DFWRM+WEQ +ATIVM+T L+E+ KC QYWP++G
Sbjct: 1007 NYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRG 1066
Query: 359 CWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPI 418
TYG I+V++ D L + VR F + + G R+ + QF FT+WPD GVP P
Sbjct: 1067 TETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKRE----VRQFQFTAWPDHGVPEYPT 1122
Query: 419 GMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIR 478
L FL++VK CNP AG IVVHCSAGVGRTG F+VIDAML+ + E+ VDVYG V+ +R
Sbjct: 1123 PFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMR 1182
Query: 479 AQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFK 538
+QR MVQT+ QY FI++ALLE G+TE+ SL ++QK+ PG G+E EFK
Sbjct: 1183 SQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQVEPGEHVTGMELEFK 1242
Query: 539 KLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYR 598
+L + K + + NLP N KNR++ I+PYE RV + RG E +DY+NASFIDGYR
Sbjct: 1243 RLANSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYR 1302
Query: 599 QKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDI 658
Q+ +YIA+QGPL T EDFWRM+WE S +VMLT+L E G+EKC QYWP++ Y
Sbjct: 1303 QQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYF 1362
Query: 659 TVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQK 718
V+ E Y +R+ VT+ R+ +SR +RQF F WPE G+P G+G I I V K
Sbjct: 1363 VVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHK 1422
Query: 719 QQQQSG-NHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQT 777
++Q G + PI+VHCSAG GRTG F LS VLER++ EG++D+FQTVK LR QRP MVQT
Sbjct: 1423 TKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQT 1482
Query: 778 LEQYEFCYKVVQEYIDAFSDYA 799
++Y+FCY+ EY+ +F YA
Sbjct: 1483 EDEYQFCYQAALEYLGSFDHYA 1504
>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
isoform 2 precursor [Homo sapiens]
Length = 1910
Score = 592 bits (1525), Expect = e-169
Identities = 312/682 (45%), Positives = 426/682 (62%), Gaps = 22/682 (3%)
Query: 134 TFPPSGNSD--SKDRRDETPII----AVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHS 187
TF S SD D D PI+ ++ + +L +VFII ++ + K K
Sbjct: 1234 TFAASPFSDPFQLDNPDPQPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRK 1293
Query: 188 NS-----FRLSNGRTEDVEPQSVPLLAR----SPSTNRKYPPLPVDKLEEEINRRMADDN 238
+S L+N P+ + R +P +PP+P+ + E R A+D+
Sbjct: 1294 DSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPGM-LSHPPIPIADMAEHTERLKANDS 1352
Query: 239 KLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINA 298
+E+ ++ Q T E ++ E NK KNRY N++ YDHSRV L P+EG+ SDYINA
Sbjct: 1353 LKLSQEYESIDPGQ-QFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINA 1411
Query: 299 SFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQG 358
++++GY+ +N +IA QGP ET DFWRM+WEQ +ATIVM+T L+E+ KC QYWP++G
Sbjct: 1412 NYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRG 1471
Query: 359 CWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPI 418
TYG I+V++ D L + VR F + + G R+ + QF FT+WPD GVP P
Sbjct: 1472 TETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKRE----VRQFQFTAWPDHGVPEYPT 1527
Query: 419 GMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIR 478
L FL++VK CNP AG IVVHCSAGVGRTG F+VIDAML+ + E+ VDVYG V+ +R
Sbjct: 1528 PFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMR 1587
Query: 479 AQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFK 538
+QR MVQT+ QY FI++ALLE G+TE+ SL ++QK+ PG G+E EFK
Sbjct: 1588 SQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQVEPGEHVTGMELEFK 1647
Query: 539 KLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYR 598
+L + K + + NLP N KNR++ I+PYE RV + RG E +DY+NASFIDGYR
Sbjct: 1648 RLANSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYR 1707
Query: 599 QKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDI 658
Q+ +YIA+QGPL T EDFWRM+WE S +VMLT+L E G+EKC QYWP++ Y
Sbjct: 1708 QQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYF 1767
Query: 659 TVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQK 718
V+ E Y +R+ VT+ R+ +SR +RQF F WPE G+P G+G I I V K
Sbjct: 1768 VVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHK 1827
Query: 719 QQQQSG-NHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQT 777
++Q G + PI+VHCSAG GRTG F LS VLER++ EG++D+FQTVK LR QRP MVQT
Sbjct: 1828 TKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQT 1887
Query: 778 LEQYEFCYKVVQEYIDAFSDYA 799
++Y+FCY+ EY+ +F YA
Sbjct: 1888 EDEYQFCYQAALEYLGSFDHYA 1909
>gi|104487295 protein tyrosine phosphatase, receptor type, sigma
isoform 3 precursor [Homo sapiens]
Length = 1501
Score = 592 bits (1525), Expect = e-169
Identities = 312/682 (45%), Positives = 426/682 (62%), Gaps = 22/682 (3%)
Query: 134 TFPPSGNSD--SKDRRDETPII----AVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHS 187
TF S SD D D PI+ ++ + +L +VFII ++ + K K
Sbjct: 825 TFAASPFSDPFQLDNPDPQPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRK 884
Query: 188 NS-----FRLSNGRTEDVEPQSVPLLAR----SPSTNRKYPPLPVDKLEEEINRRMADDN 238
+S L+N P+ + R +P +PP+P+ + E R A+D+
Sbjct: 885 DSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPGM-LSHPPIPIADMAEHTERLKANDS 943
Query: 239 KLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINA 298
+E+ ++ Q T E ++ E NK KNRY N++ YDHSRV L P+EG+ SDYINA
Sbjct: 944 LKLSQEYESIDPGQ-QFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINA 1002
Query: 299 SFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQG 358
++++GY+ +N +IA QGP ET DFWRM+WEQ +ATIVM+T L+E+ KC QYWP++G
Sbjct: 1003 NYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRG 1062
Query: 359 CWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPI 418
TYG I+V++ D L + VR F + + G R+ + QF FT+WPD GVP P
Sbjct: 1063 TETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKRE----VRQFQFTAWPDHGVPEYPT 1118
Query: 419 GMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIR 478
L FL++VK CNP AG IVVHCSAGVGRTG F+VIDAML+ + E+ VDVYG V+ +R
Sbjct: 1119 PFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMR 1178
Query: 479 AQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFK 538
+QR MVQT+ QY FI++ALLE G+TE+ SL ++QK+ PG G+E EFK
Sbjct: 1179 SQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQVEPGEHVTGMELEFK 1238
Query: 539 KLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYR 598
+L + K + + NLP N KNR++ I+PYE RV + RG E +DY+NASFIDGYR
Sbjct: 1239 RLANSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYR 1298
Query: 599 QKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDI 658
Q+ +YIA+QGPL T EDFWRM+WE S +VMLT+L E G+EKC QYWP++ Y
Sbjct: 1299 QQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYF 1358
Query: 659 TVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQK 718
V+ E Y +R+ VT+ R+ +SR +RQF F WPE G+P G+G I I V K
Sbjct: 1359 VVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHK 1418
Query: 719 QQQQSG-NHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQT 777
++Q G + PI+VHCSAG GRTG F LS VLER++ EG++D+FQTVK LR QRP MVQT
Sbjct: 1419 TKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQT 1478
Query: 778 LEQYEFCYKVVQEYIDAFSDYA 799
++Y+FCY+ EY+ +F YA
Sbjct: 1479 EDEYQFCYQAALEYLGSFDHYA 1500
>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
isoform 1 precursor [Homo sapiens]
Length = 1948
Score = 588 bits (1516), Expect = e-168
Identities = 316/700 (45%), Positives = 430/700 (61%), Gaps = 42/700 (6%)
Query: 134 TFPPSGNSD--SKDRRDETPII----AVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHS 187
TF S SD D D PI+ ++ + +L +VFII ++ + K K
Sbjct: 1256 TFAASPFSDPFQLDNPDPQPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRK 1315
Query: 188 NS-----------------------FRLSNGRTEDVEPQSVPLLARSPSTNRK----YPP 220
+S R N +T D +S PL R P + + +PP
Sbjct: 1316 DSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPDSGLRS-PL--REPGFHFESMLSHPP 1372
Query: 221 LPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHS 280
+P+ + E R A+D+ +E+ ++ Q T E ++ E NK KNRY N++ YDHS
Sbjct: 1373 IPIADMAEHTERLKANDSLKLSQEYESIDPGQ-QFTWEHSNLEVNKPKNRYANVIAYDHS 1431
Query: 281 RVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVT 340
RV L P+EG+ SDYINA++++GY+ +N +IA QGP ET DFWRM+WEQ +ATIVM+T
Sbjct: 1432 RVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMT 1491
Query: 341 NLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLI 400
L+E+ KC QYWP++G TYG I+V++ D L + VR F + + G R+ +
Sbjct: 1492 RLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKRE----V 1547
Query: 401 TQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLD 460
QF FT+WPD GVP P L FL++VK CNP AG IVVHCSAGVGRTG F+VIDAML+
Sbjct: 1548 RQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLE 1607
Query: 461 MMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQK 520
+ E+ VDVYG V+ +R+QR MVQT+ QY FI++ALLE G+TE+ SL ++QK
Sbjct: 1608 RIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQK 1667
Query: 521 IYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVK 580
+ PG G+E EFK+L + K + + NLP N KNR++ I+PYE RV +
Sbjct: 1668 LAQVEPGEHVTGMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPI 1727
Query: 581 RGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQ 640
RG E +DY+NASFIDGYRQ+ +YIA+QGPL T EDFWRM+WE S +VMLT+L E G+
Sbjct: 1728 RGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGR 1787
Query: 641 EKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEV 700
EKC QYWP++ Y V+ E Y +R+ VT+ R+ +SR +RQF F WPE
Sbjct: 1788 EKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQ 1847
Query: 701 GIPSDGKGMISIIAAVQKQQQQSG-NHPITVHCSAGAGRTGTFCALSTVLERVKAEGILD 759
G+P G+G I I V K ++Q G + PI+VHCSAG GRTG F LS VLER++ EG++D
Sbjct: 1848 GVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1907
Query: 760 VFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAFSDYA 799
+FQTVK LR QRP MVQT ++Y+FCY+ EY+ +F YA
Sbjct: 1908 IFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYA 1947
>gi|18641364 protein tyrosine phosphatase, receptor type, C isoform 3
precursor [Homo sapiens]
Length = 1256
Score = 471 bits (1212), Expect = e-132
Identities = 267/668 (39%), Positives = 391/668 (58%), Gaps = 56/668 (8%)
Query: 156 MVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTN 215
++A + L+IV I +L +L YK H + + E VE L
Sbjct: 529 LIAFLAFLIIVTSIALLVVL----YKIYDLHKKRSCNLDEQQELVERDDEKQLMN----- 579
Query: 216 RKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNIL 275
P+ D L E R++AD+ +LF EF ++P + + A K N+ KNRYV+IL
Sbjct: 580 --VEPIHADILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDIL 637
Query: 276 PYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTAT 335
PYD++RV L+ + G S+YINAS+I+G++E K+IAAQGP++ETV+DFWRMIWEQ
Sbjct: 638 PYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATV 697
Query: 336 IVMVTNLKERKECKCAQYWP--DQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTN 393
IVMVT +E KCA+YWP ++G +G++ V + DY ++K ++ N
Sbjct: 698 IVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKL------NIVN 751
Query: 394 RKPQ---RLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTG 450
+K + R +T FTSWPD GVP P +LK ++V A + ++G IVVHCSAGVGRTG
Sbjct: 752 KKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTG 811
Query: 451 TFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELE 510
T++ IDAML+ + E KVDVYG+V ++R QRC MVQ + QY+ I+QAL+E+ +G+TE+
Sbjct: 812 TYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVN 871
Query: 511 VTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPY 570
++ L +L + + P + + LE EF++L S + + GN N KNR +IPY
Sbjct: 872 LSELHPYLHNMKKRDPPSEPSPLEAEFQRLPSYRSWRTQ-HIGNQEENKSKNRNSNVIPY 930
Query: 571 EFNRVIIPVKR---------------------GEENTDYVNASFIDGYRQKDSYIASQGP 609
++NRV P+K EE + Y+NASFI Y + + IA+QGP
Sbjct: 931 DYNRV--PLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSYWKPEVMIAAQGP 988
Query: 610 LLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECE 669
L TI DFW+MI++ K IVMLTEL+ QE CAQYW +G +YGDI V+LK ++
Sbjct: 989 LKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYW-GEGKQTYGDIEVDLKDTDKSS 1047
Query: 670 SYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAV-----QKQQQQSG 724
+YT+R + +++ SR + Q+ + W +P++ K +IS+I V QK +
Sbjct: 1048 TYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGN 1107
Query: 725 NH----PITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ 780
H P+ +HC G+ +TG FCAL +LE + E ++D+FQ VK+LR RP MV T EQ
Sbjct: 1108 KHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQ 1167
Query: 781 YEFCYKVV 788
Y+F Y V+
Sbjct: 1168 YQFLYDVI 1175
Score = 197 bits (501), Expect = 3e-50
Identities = 96/239 (40%), Positives = 146/239 (61%), Gaps = 4/239 (1%)
Query: 556 PANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIE 615
P N KNR + I+PY++NRV + G+ ++Y+NAS+IDG+++ YIA+QGP T++
Sbjct: 625 PFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVD 684
Query: 616 DFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPS--DGLVSYGDITVELKKEEECESYTV 673
DFWRMIWE K+ IVM+T EE + KCA+YWPS +G ++GD+ V++ + + C Y +
Sbjct: 685 DFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYII 744
Query: 674 RDLLVTNTRENKS-RQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHC 732
+ L + N +E + R++ F WP+ G+P D ++ + V PI VHC
Sbjct: 745 QKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSG-PIVVHC 803
Query: 733 SAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEY 791
SAG GRTGT+ + +LE ++AE +DV+ V LR QR MVQ QY ++ + EY
Sbjct: 804 SAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY 862
Score = 160 bits (404), Expect = 6e-39
Identities = 100/288 (34%), Positives = 146/288 (50%), Gaps = 34/288 (11%)
Query: 244 EFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLT-----PVEGVPDSD---- 294
EF LP+ T ++EENK KNR N++PYD++RV L E DSD
Sbjct: 897 EFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSD 956
Query: 295 ----------YINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKE 344
YINASFI Y + IAAQGP +ET+ DFW+MI+++ IVM+T LK
Sbjct: 957 DDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKH 1016
Query: 345 RKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFH 404
+ CAQYW +G TYG+I V ++D YT+R F ++ + RK R + Q+
Sbjct: 1017 GDQEICAQYW-GEGKQTYGDIEVDLKDTDKSSTYTLRVFELRH----SKRKDSRTVYQYQ 1071
Query: 405 FTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGA----------IVVHCSAGVGRTGTFVV 454
+T+W +P P ++ ++ VK PQ + +++HC G +TG F
Sbjct: 1072 YTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCA 1131
Query: 455 IDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHY 502
+ +L+ TE VD++ V +R R MV T QY F+Y + Y
Sbjct: 1132 LLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTY 1179
>gi|18641347 protein tyrosine phosphatase, receptor type, C isoform 1
precursor [Homo sapiens]
Length = 1304
Score = 471 bits (1212), Expect = e-132
Identities = 267/668 (39%), Positives = 391/668 (58%), Gaps = 56/668 (8%)
Query: 156 MVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTN 215
++A + L+IV I +L +L YK H + + E VE L
Sbjct: 577 LIAFLAFLIIVTSIALLVVL----YKIYDLHKKRSCNLDEQQELVERDDEKQLMN----- 627
Query: 216 RKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNIL 275
P+ D L E R++AD+ +LF EF ++P + + A K N+ KNRYV+IL
Sbjct: 628 --VEPIHADILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDIL 685
Query: 276 PYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTAT 335
PYD++RV L+ + G S+YINAS+I+G++E K+IAAQGP++ETV+DFWRMIWEQ
Sbjct: 686 PYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATV 745
Query: 336 IVMVTNLKERKECKCAQYWP--DQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTN 393
IVMVT +E KCA+YWP ++G +G++ V + DY ++K ++ N
Sbjct: 746 IVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKL------NIVN 799
Query: 394 RKPQ---RLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTG 450
+K + R +T FTSWPD GVP P +LK ++V A + ++G IVVHCSAGVGRTG
Sbjct: 800 KKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTG 859
Query: 451 TFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELE 510
T++ IDAML+ + E KVDVYG+V ++R QRC MVQ + QY+ I+QAL+E+ +G+TE+
Sbjct: 860 TYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVN 919
Query: 511 VTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPY 570
++ L +L + + P + + LE EF++L S + + GN N KNR +IPY
Sbjct: 920 LSELHPYLHNMKKRDPPSEPSPLEAEFQRLPSYRSWRTQ-HIGNQEENKSKNRNSNVIPY 978
Query: 571 EFNRVIIPVKR---------------------GEENTDYVNASFIDGYRQKDSYIASQGP 609
++NRV P+K EE + Y+NASFI Y + + IA+QGP
Sbjct: 979 DYNRV--PLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSYWKPEVMIAAQGP 1036
Query: 610 LLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECE 669
L TI DFW+MI++ K IVMLTEL+ QE CAQYW +G +YGDI V+LK ++
Sbjct: 1037 LKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYW-GEGKQTYGDIEVDLKDTDKSS 1095
Query: 670 SYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAV-----QKQQQQSG 724
+YT+R + +++ SR + Q+ + W +P++ K +IS+I V QK +
Sbjct: 1096 TYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGN 1155
Query: 725 NH----PITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ 780
H P+ +HC G+ +TG FCAL +LE + E ++D+FQ VK+LR RP MV T EQ
Sbjct: 1156 KHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQ 1215
Query: 781 YEFCYKVV 788
Y+F Y V+
Sbjct: 1216 YQFLYDVI 1223
Score = 197 bits (501), Expect = 3e-50
Identities = 96/239 (40%), Positives = 146/239 (61%), Gaps = 4/239 (1%)
Query: 556 PANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIE 615
P N KNR + I+PY++NRV + G+ ++Y+NAS+IDG+++ YIA+QGP T++
Sbjct: 673 PFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVD 732
Query: 616 DFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPS--DGLVSYGDITVELKKEEECESYTV 673
DFWRMIWE K+ IVM+T EE + KCA+YWPS +G ++GD+ V++ + + C Y +
Sbjct: 733 DFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYII 792
Query: 674 RDLLVTNTRENKS-RQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHC 732
+ L + N +E + R++ F WP+ G+P D ++ + V PI VHC
Sbjct: 793 QKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSG-PIVVHC 851
Query: 733 SAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEY 791
SAG GRTGT+ + +LE ++AE +DV+ V LR QR MVQ QY ++ + EY
Sbjct: 852 SAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY 910
Score = 160 bits (404), Expect = 6e-39
Identities = 100/288 (34%), Positives = 146/288 (50%), Gaps = 34/288 (11%)
Query: 244 EFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLT-----PVEGVPDSD---- 294
EF LP+ T ++EENK KNR N++PYD++RV L E DSD
Sbjct: 945 EFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSD 1004
Query: 295 ----------YINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKE 344
YINASFI Y + IAAQGP +ET+ DFW+MI+++ IVM+T LK
Sbjct: 1005 DDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKH 1064
Query: 345 RKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFH 404
+ CAQYW +G TYG+I V ++D YT+R F ++ + RK R + Q+
Sbjct: 1065 GDQEICAQYW-GEGKQTYGDIEVDLKDTDKSSTYTLRVFELRH----SKRKDSRTVYQYQ 1119
Query: 405 FTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGA----------IVVHCSAGVGRTGTFVV 454
+T+W +P P ++ ++ VK PQ + +++HC G +TG F
Sbjct: 1120 YTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCA 1179
Query: 455 IDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHY 502
+ +L+ TE VD++ V +R R MV T QY F+Y + Y
Sbjct: 1180 LLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTY 1227
>gi|18641362 protein tyrosine phosphatase, receptor type, C isoform 2
precursor [Homo sapiens]
Length = 1143
Score = 471 bits (1212), Expect = e-132
Identities = 267/668 (39%), Positives = 391/668 (58%), Gaps = 56/668 (8%)
Query: 156 MVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTN 215
++A + L+IV I +L +L YK H + + E VE L
Sbjct: 416 LIAFLAFLIIVTSIALLVVL----YKIYDLHKKRSCNLDEQQELVERDDEKQLMN----- 466
Query: 216 RKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNIL 275
P+ D L E R++AD+ +LF EF ++P + + A K N+ KNRYV+IL
Sbjct: 467 --VEPIHADILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDIL 524
Query: 276 PYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTAT 335
PYD++RV L+ + G S+YINAS+I+G++E K+IAAQGP++ETV+DFWRMIWEQ
Sbjct: 525 PYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATV 584
Query: 336 IVMVTNLKERKECKCAQYWP--DQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTN 393
IVMVT +E KCA+YWP ++G +G++ V + DY ++K ++ N
Sbjct: 585 IVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKL------NIVN 638
Query: 394 RKPQ---RLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTG 450
+K + R +T FTSWPD GVP P +LK ++V A + ++G IVVHCSAGVGRTG
Sbjct: 639 KKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTG 698
Query: 451 TFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELE 510
T++ IDAML+ + E KVDVYG+V ++R QRC MVQ + QY+ I+QAL+E+ +G+TE+
Sbjct: 699 TYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVN 758
Query: 511 VTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPY 570
++ L +L + + P + + LE EF++L S + + GN N KNR +IPY
Sbjct: 759 LSELHPYLHNMKKRDPPSEPSPLEAEFQRLPSYRSWRTQ-HIGNQEENKSKNRNSNVIPY 817
Query: 571 EFNRVIIPVKR---------------------GEENTDYVNASFIDGYRQKDSYIASQGP 609
++NRV P+K EE + Y+NASFI Y + + IA+QGP
Sbjct: 818 DYNRV--PLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSYWKPEVMIAAQGP 875
Query: 610 LLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECE 669
L TI DFW+MI++ K IVMLTEL+ QE CAQYW +G +YGDI V+LK ++
Sbjct: 876 LKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYW-GEGKQTYGDIEVDLKDTDKSS 934
Query: 670 SYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAV-----QKQQQQSG 724
+YT+R + +++ SR + Q+ + W +P++ K +IS+I V QK +
Sbjct: 935 TYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGN 994
Query: 725 NH----PITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQ 780
H P+ +HC G+ +TG FCAL +LE + E ++D+FQ VK+LR RP MV T EQ
Sbjct: 995 KHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQ 1054
Query: 781 YEFCYKVV 788
Y+F Y V+
Sbjct: 1055 YQFLYDVI 1062
Score = 197 bits (501), Expect = 3e-50
Identities = 96/239 (40%), Positives = 146/239 (61%), Gaps = 4/239 (1%)
Query: 556 PANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIE 615
P N KNR + I+PY++NRV + G+ ++Y+NAS+IDG+++ YIA+QGP T++
Sbjct: 512 PFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVD 571
Query: 616 DFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPS--DGLVSYGDITVELKKEEECESYTV 673
DFWRMIWE K+ IVM+T EE + KCA+YWPS +G ++GD+ V++ + + C Y +
Sbjct: 572 DFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYII 631
Query: 674 RDLLVTNTRENKS-RQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHC 732
+ L + N +E + R++ F WP+ G+P D ++ + V PI VHC
Sbjct: 632 QKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSG-PIVVHC 690
Query: 733 SAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEY 791
SAG GRTGT+ + +LE ++AE +DV+ V LR QR MVQ QY ++ + EY
Sbjct: 691 SAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY 749
Score = 160 bits (404), Expect = 6e-39
Identities = 100/288 (34%), Positives = 146/288 (50%), Gaps = 34/288 (11%)
Query: 244 EFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLT-----PVEGVPDSD---- 294
EF LP+ T ++EENK KNR N++PYD++RV L E DSD
Sbjct: 784 EFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSD 843
Query: 295 ----------YINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKE 344
YINASFI Y + IAAQGP +ET+ DFW+MI+++ IVM+T LK
Sbjct: 844 DDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKH 903
Query: 345 RKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFH 404
+ CAQYW +G TYG+I V ++D YT+R F ++ + RK R + Q+
Sbjct: 904 GDQEICAQYW-GEGKQTYGDIEVDLKDTDKSSTYTLRVFELRH----SKRKDSRTVYQYQ 958
Query: 405 FTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGA----------IVVHCSAGVGRTGTFVV 454
+T+W +P P ++ ++ VK PQ + +++HC G +TG F
Sbjct: 959 YTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCA 1018
Query: 455 IDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHY 502
+ +L+ TE VD++ V +R R MV T QY F+Y + Y
Sbjct: 1019 LLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTY 1066
>gi|18860902 protein tyrosine phosphatase, receptor type, K isoform b
[Homo sapiens]
Length = 1440
Score = 441 bits (1135), Expect = e-123
Identities = 236/588 (40%), Positives = 356/588 (60%), Gaps = 16/588 (2%)
Query: 214 TNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVN 273
T + +P + V L + IN D+ F+EE+ + A+ + A K++N+ KNRY N
Sbjct: 861 TGQLHPAIRVADLLQHINLMKTSDSYGFKEEYESFFEGQ-SASWDVAKKDQNRAKNRYGN 919
Query: 274 ILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNT 333
I+ YDHSRV L PVE P SDYINA++I+GYQ + +IA QGP ETV DFWRMIW++ +
Sbjct: 920 IIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETVYDFWRMIWQEQS 979
Query: 334 ATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTN 393
A IVMVTNL E KC +YWPD YG+ +V+ ++ L +Y VR F +++ G
Sbjct: 980 ACIVMVTNLVEVGRVKCYKYWPDD-TEVYGDFKVTCVEMEPLAEYVVRTFTLERRGYNEI 1038
Query: 394 RKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFV 453
R+ + QFHFT WPD GVP+ G+L F+++VK NP AG IVVHCSAG GRTG ++
Sbjct: 1039 RE----VKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPPSAGPIVVHCSAGAGRTGCYI 1094
Query: 454 VIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTS 513
VID MLDM E VD+Y V +R++R MVQT+ QY+FI+ A+LE L G+T + V
Sbjct: 1095 VIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEACLCGETAIPVCE 1154
Query: 514 LETHLQKIYNKIPGTSNNGLEEEFKKLTSI--KIQNDKMRTGNLPANMKKNRVLQIIPYE 571
+ + T+++ L++EF+ L S+ ++Q + LP N KNR + ++P +
Sbjct: 1155 FKAAYFDMIRIDSQTNSSHLKDEFQTLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPD 1214
Query: 572 FNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVM 631
+ G E+++Y+NA+ +D YRQ ++I +Q PL +T++DFWR+++++ SIVM
Sbjct: 1215 RCLPFLITIDG-ESSNYINAALMDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVM 1273
Query: 632 LTELEERGQEKCAQYWPSDGLVSYGDITVE-LKKEEECESYTVRDLLVTNTRENKS-RQI 689
L E++ + C QYWP +G++ YG I VE + +C+ + TR + +
Sbjct: 1274 LNEVDL--SQGCPQYWPEEGMLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLMV 1331
Query: 690 RQFHFHGW-PEVGIPSDGKGMISIIAAVQKQQQ--QSGNHPITVHCSAGAGRTGTFCALS 746
+QF + GW +P + + +I V+K Q+ + G +HC G GR+G FCA+
Sbjct: 1332 QQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIG 1391
Query: 747 TVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDA 794
V+E VK + ++DVF VK+LR +P+MV+ EQY FCY V EY+++
Sbjct: 1392 IVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLES 1439
>gi|157419150 protein tyrosine phosphatase, receptor type, M isoform 2
precursor [Homo sapiens]
Length = 1452
Score = 440 bits (1131), Expect = e-123
Identities = 235/601 (39%), Positives = 361/601 (60%), Gaps = 21/601 (3%)
Query: 201 EPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAA 260
EP VP T + +P + V L + I + + F+EE+ + A ++A
Sbjct: 865 EPADVPY-----QTGQLHPAIRVADLLQHITQMKCAEGYGFKEEYESFFEGQ-SAPWDSA 918
Query: 261 SKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEET 320
K+EN+ KNRY NI+ YDHSRV L +EG +SDYIN ++I+GY N +IA QGP +ET
Sbjct: 919 KKDENRMKNRYGNIIAYDHSRVRLQTIEGDTNSDYINGNYIDGYHRPNHYIATQGPMQET 978
Query: 321 VNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTV 380
+ DFWRM+W +NTA+I+MVTNL E KC +YWPD Y +I+V++ + +L +Y +
Sbjct: 979 IYDFWRMVWHENTASIIMVTNLVEVGRVKCCKYWPDD-TEIYKDIKVTLIETELLAEYVI 1037
Query: 381 RKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVV 440
R F +++ G R+ I QFHFT WPD GVP+ G+L F+++VK+ +P AG +VV
Sbjct: 1038 RTFAVEKRGVHEIRE----IRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSPPSAGPLVV 1093
Query: 441 HCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLE 500
HCSAG GRTG F+VID MLDM E VD+Y V +R++R MVQT+ QYVFI+ A+LE
Sbjct: 1094 HCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILE 1153
Query: 501 HYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSI--KIQNDKMRTGNLPAN 558
L GDT + + + + + P T+++ ++EEF+ L + ++ + LP N
Sbjct: 1154 ACLCGDTSVPASQVRSLYYDMNKLDPQTNSSQIKEEFRTLNMVTPTLRVEDCSIALLPRN 1213
Query: 559 MKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFW 618
+KNR + I+P + + G E+++Y+NA+ +D Y+Q ++I +Q PL +T++DFW
Sbjct: 1214 HEKNRCMDILPPDRCLPFLITIDG-ESSNYINAALMDSYKQPSAFIVTQHPLPNTVKDFW 1272
Query: 619 RMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLV 678
R++ ++ S+VML +++ + C QYWP +G+ +G I VE + E R +
Sbjct: 1273 RLVLDYHCTSVVMLNDVDP--AQLCPQYWPENGVHRHGPIQVEFVSADLEEDIISRIFRI 1330
Query: 679 TNTR--ENKSRQIRQFHFHGWPEV-GIPSDGKGMISIIAAVQKQQQQ--SGNHPITVHCS 733
N ++ R ++QF F GWP P + + +I V K Q++ G VHC
Sbjct: 1331 YNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRTVVHCL 1390
Query: 734 AGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID 793
G GR+GTFCA+S V E ++ + +DVF VK+LR +P+MV L+QY+FCY+V EY++
Sbjct: 1391 NGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLN 1450
Query: 794 A 794
+
Sbjct: 1451 S 1451
>gi|157419152 protein tyrosine phosphatase, receptor type, M isoform 1
precursor [Homo sapiens]
Length = 1465
Score = 440 bits (1131), Expect = e-123
Identities = 235/601 (39%), Positives = 361/601 (60%), Gaps = 21/601 (3%)
Query: 201 EPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAA 260
EP VP T + +P + V L + I + + F+EE+ + A ++A
Sbjct: 878 EPADVPY-----QTGQLHPAIRVADLLQHITQMKCAEGYGFKEEYESFFEGQ-SAPWDSA 931
Query: 261 SKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEET 320
K+EN+ KNRY NI+ YDHSRV L +EG +SDYIN ++I+GY N +IA QGP +ET
Sbjct: 932 KKDENRMKNRYGNIIAYDHSRVRLQTIEGDTNSDYINGNYIDGYHRPNHYIATQGPMQET 991
Query: 321 VNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTV 380
+ DFWRM+W +NTA+I+MVTNL E KC +YWPD Y +I+V++ + +L +Y +
Sbjct: 992 IYDFWRMVWHENTASIIMVTNLVEVGRVKCCKYWPDD-TEIYKDIKVTLIETELLAEYVI 1050
Query: 381 RKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVV 440
R F +++ G R+ I QFHFT WPD GVP+ G+L F+++VK+ +P AG +VV
Sbjct: 1051 RTFAVEKRGVHEIRE----IRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSPPSAGPLVV 1106
Query: 441 HCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLE 500
HCSAG GRTG F+VID MLDM E VD+Y V +R++R MVQT+ QYVFI+ A+LE
Sbjct: 1107 HCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILE 1166
Query: 501 HYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSI--KIQNDKMRTGNLPAN 558
L GDT + + + + + P T+++ ++EEF+ L + ++ + LP N
Sbjct: 1167 ACLCGDTSVPASQVRSLYYDMNKLDPQTNSSQIKEEFRTLNMVTPTLRVEDCSIALLPRN 1226
Query: 559 MKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFW 618
+KNR + I+P + + G E+++Y+NA+ +D Y+Q ++I +Q PL +T++DFW
Sbjct: 1227 HEKNRCMDILPPDRCLPFLITIDG-ESSNYINAALMDSYKQPSAFIVTQHPLPNTVKDFW 1285
Query: 619 RMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLV 678
R++ ++ S+VML +++ + C QYWP +G+ +G I VE + E R +
Sbjct: 1286 RLVLDYHCTSVVMLNDVDP--AQLCPQYWPENGVHRHGPIQVEFVSADLEEDIISRIFRI 1343
Query: 679 TNTR--ENKSRQIRQFHFHGWPEV-GIPSDGKGMISIIAAVQKQQQQ--SGNHPITVHCS 733
N ++ R ++QF F GWP P + + +I V K Q++ G VHC
Sbjct: 1344 YNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRTVVHCL 1403
Query: 734 AGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID 793
G GR+GTFCA+S V E ++ + +DVF VK+LR +P+MV L+QY+FCY+V EY++
Sbjct: 1404 NGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLN 1463
Query: 794 A 794
+
Sbjct: 1464 S 1464
>gi|208431815 protein tyrosine phosphatase, receptor type, K isoform a
[Homo sapiens]
Length = 1446
Score = 435 bits (1118), Expect = e-122
Identities = 236/594 (39%), Positives = 356/594 (59%), Gaps = 22/594 (3%)
Query: 214 TNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVN 273
T + +P + V L + IN D+ F+EE+ + A+ + A K++N+ KNRY N
Sbjct: 861 TGQLHPAIRVADLLQHINLMKTSDSYGFKEEYESFFEGQ-SASWDVAKKDQNRAKNRYGN 919
Query: 274 ILPYDHSRVHLTPVEGVPDSDYINASFIN------GYQEKNKFIAAQGPKEETVNDFWRM 327
I+ YDHSRV L PVE P SDYINA++I+ GYQ + +IA QGP ETV DFWRM
Sbjct: 920 IIAYDHSRVILQPVEDDPSSDYINANYIDIWLYRDGYQRPSHYIATQGPVHETVYDFWRM 979
Query: 328 IWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQ 387
IW++ +A IVMVTNL E KC +YWPD YG+ +V+ ++ L +Y VR F +++
Sbjct: 980 IWQEQSACIVMVTNLVEVGRVKCYKYWPDD-TEVYGDFKVTCVEMEPLAEYVVRTFTLER 1038
Query: 388 VGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVG 447
G R+ + QFHFT WPD GVP+ G+L F+++VK NP AG IVVHCSAG G
Sbjct: 1039 RGYNEIRE----VKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPPSAGPIVVHCSAGAG 1094
Query: 448 RTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDT 507
RTG ++VID MLDM E VD+Y V +R++R MVQT+ QY+FI+ A+LE L G+T
Sbjct: 1095 RTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEACLCGET 1154
Query: 508 ELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSI--KIQNDKMRTGNLPANMKKNRVL 565
+ V + + T+++ L++EF+ L S+ ++Q + LP N KNR +
Sbjct: 1155 AIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQTLNSVTPRLQAEDCSIACLPRNHDKNRFM 1214
Query: 566 QIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWK 625
++P + + G E+++Y+NA+ +D YRQ ++I +Q PL +T++DFWR+++++
Sbjct: 1215 DMLPPDRCLPFLITIDG-ESSNYINAALMDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYG 1273
Query: 626 SCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVE-LKKEEECESYTVRDLLVTNTREN 684
SIVML E++ + C QYWP +G++ YG I VE + +C+ + TR
Sbjct: 1274 CTSIVMLNEVDL--SQGCPQYWPEEGMLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQ 1331
Query: 685 KS-RQIRQFHFHGW-PEVGIPSDGKGMISIIAAVQKQQQ--QSGNHPITVHCSAGAGRTG 740
+ ++QF + GW +P + + +I V+K Q+ + G +HC G GR+G
Sbjct: 1332 EGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSG 1391
Query: 741 TFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDA 794
FCA+ V+E VK + ++DVF VK+LR +P+MV+ EQY FCY V EY+++
Sbjct: 1392 MFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLES 1445
>gi|148539860 protein tyrosine phosphatase, receptor type, T isoform 2
precursor [Homo sapiens]
Length = 1441
Score = 434 bits (1117), Expect = e-121
Identities = 231/584 (39%), Positives = 352/584 (60%), Gaps = 16/584 (2%)
Query: 219 PPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYD 278
P + V L + I + F+EE+ ALP A+ + A ++EN+ KNRY NI+ YD
Sbjct: 867 PAIRVADLLQHITQMKRGQGYGFKEEYEALPEGQT-ASWDTAKEDENRNKNRYGNIISYD 925
Query: 279 HSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVM 338
HSRV L ++G P SDYINA++I+GY +IA QGP +ETV DFWRMIW++N+A+IVM
Sbjct: 926 HSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVM 985
Query: 339 VTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQR 398
VTNL E KC +YWPD YG+I+V++ + L +Y +R F +Q+ G R+
Sbjct: 986 VTNLVEVGRVKCVRYWPDD-TEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRE--- 1041
Query: 399 LITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAM 458
+ FHFTSWPD GVP G+L F+++VK NP AG IVVHCSAG GRTG F+ ID M
Sbjct: 1042 -LRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTM 1100
Query: 459 LDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHL 518
LDM E VD++ V +RAQR +VQT+ QYVF++ A+LE L G+T + V +
Sbjct: 1101 LDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLY 1160
Query: 519 QKIYNKIPGTSNNGLEEEFKKLTSI--KIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVI 576
I P T+++ +++EF+ L + +++ + G LP N KNR + ++P + +
Sbjct: 1161 YNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLD-RCLP 1219
Query: 577 IPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELE 636
+ E+++Y+NA+ +D ++Q +++ +Q PL +T+ DFWR+++++ S+VML E++
Sbjct: 1220 FLISVDGESSNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMD 1279
Query: 637 ERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTR--ENKSRQIRQFHF 694
+ C QYWP YG I VE + E R + N ++ R ++ +
Sbjct: 1280 T--AQFCMQYWPEKTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQY 1337
Query: 695 HGWPEV-GIPSDGKGMISIIAAVQK-QQQQSGNHPIT-VHCSAGAGRTGTFCALSTVLER 751
GWP P + ++ ++ ++K Q+Q G T VHC G GR+GTFCA+ +V E
Sbjct: 1338 IGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEM 1397
Query: 752 VKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAF 795
++ + I+DVF VK+LR + +MV+TLEQY+F Y+V EY+ +F
Sbjct: 1398 IQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF 1441
>gi|148539858 protein tyrosine phosphatase, receptor type, T isoform 1
precursor [Homo sapiens]
Length = 1460
Score = 434 bits (1117), Expect = e-121
Identities = 231/584 (39%), Positives = 352/584 (60%), Gaps = 16/584 (2%)
Query: 219 PPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYD 278
P + V L + I + F+EE+ ALP A+ + A ++EN+ KNRY NI+ YD
Sbjct: 886 PAIRVADLLQHITQMKRGQGYGFKEEYEALPEGQT-ASWDTAKEDENRNKNRYGNIISYD 944
Query: 279 HSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVM 338
HSRV L ++G P SDYINA++I+GY +IA QGP +ETV DFWRMIW++N+A+IVM
Sbjct: 945 HSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVM 1004
Query: 339 VTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQR 398
VTNL E KC +YWPD YG+I+V++ + L +Y +R F +Q+ G R+
Sbjct: 1005 VTNLVEVGRVKCVRYWPDD-TEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRE--- 1060
Query: 399 LITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAM 458
+ FHFTSWPD GVP G+L F+++VK NP AG IVVHCSAG GRTG F+ ID M
Sbjct: 1061 -LRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTM 1119
Query: 459 LDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHL 518
LDM E VD++ V +RAQR +VQT+ QYVF++ A+LE L G+T + V +
Sbjct: 1120 LDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLY 1179
Query: 519 QKIYNKIPGTSNNGLEEEFKKLTSI--KIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVI 576
I P T+++ +++EF+ L + +++ + G LP N KNR + ++P + +
Sbjct: 1180 YNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLD-RCLP 1238
Query: 577 IPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELE 636
+ E+++Y+NA+ +D ++Q +++ +Q PL +T+ DFWR+++++ S+VML E++
Sbjct: 1239 FLISVDGESSNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMD 1298
Query: 637 ERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTR--ENKSRQIRQFHF 694
+ C QYWP YG I VE + E R + N ++ R ++ +
Sbjct: 1299 T--AQFCMQYWPEKTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQY 1356
Query: 695 HGWPEV-GIPSDGKGMISIIAAVQK-QQQQSGNHPIT-VHCSAGAGRTGTFCALSTVLER 751
GWP P + ++ ++ ++K Q+Q G T VHC G GR+GTFCA+ +V E
Sbjct: 1357 IGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEM 1416
Query: 752 VKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAF 795
++ + I+DVF VK+LR + +MV+TLEQY+F Y+V EY+ +F
Sbjct: 1417 IQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF 1460
>gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1
precursor [Homo sapiens]
Length = 2315
Score = 405 bits (1041), Expect = e-113
Identities = 257/750 (34%), Positives = 395/750 (52%), Gaps = 50/750 (6%)
Query: 76 LTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFT----DARTEPWEGNSSTAATT 131
LT+ S S GT+ + + N S T D D+ P S T++ T
Sbjct: 1543 LTSDEESGSGQGTSDSLNENETSTDFSFADTNEKDADGILAAGDSEITPGFPQSPTSSVT 1602
Query: 132 PETFP-------PSGNSDSKDR-------RDETPIIAVMVALSSLLVIVFIIIVLYMLRF 177
E + NS + R E + +V +S+L I +++V ++ +
Sbjct: 1603 SENSEVFHVSEAEASNSSHESRIGLAEGLESEKKAVIPLVIVSALTFICLVVLVGILIYW 1662
Query: 178 KKYKQAGSHSNSFRLSNGRTEDVEPQSV-PLLARSPSTNRKYPPLPVDKLEEEINRRMAD 236
+K Q +H ++ R P + P+ + K+ P V L +
Sbjct: 1663 RKCFQT-AHFYLEDSTSPRVISTPPTPIFPISDDVGAIPIKHFPKHVADLHASSG--FTE 1719
Query: 237 DNKLFREEFNALPACPIQA--TCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPD-- 292
+ + +E + + +C + T ++++ +NK KNRY+NI+ YDHSRV L +
Sbjct: 1720 EFETLKEFYQEVQSCTVDLGITADSSNHPDNKHKNRYINIVAYDHSRVKLAQLAEKDGKL 1779
Query: 293 SDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQ 352
+DYINA++++GY +IAAQGP + T DFWRMIWE N IVM+TNL E+ KC Q
Sbjct: 1780 TDYINANYVDGYNRPKAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEKGRRKCDQ 1839
Query: 353 YWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQV----GDMTNRKPQRLITQFHFTSW 408
YWP G YGN V+ + V VL YTVR F ++ G R R++TQ+H+T W
Sbjct: 1840 YWPADGSEEYGNFLVTQKSVQVLAYYTVRNFTLRNTKIKKGSQKGRPSGRVVTQYHYTQW 1899
Query: 409 PDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKV 468
PD GVP + +L F++K G +VVHCSAGVGRTGT++V+D+ML + E V
Sbjct: 1900 PDMGVPEYSLPVLTFVRKAAYAKRHAVGPVVVHCSAGVGRTGTYIVLDSMLQQIQHEGTV 1959
Query: 469 DVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNK--IP 526
+++GF+ IR+QR +VQT+ QYVFI+ L+E L +TE+ L++H+ N IP
Sbjct: 1960 NIFGFLKHIRSQRNYLVQTEEQYVFIHDTLVEAILSKETEV----LDSHIHAYVNALLIP 2015
Query: 527 G-TSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEEN 585
G LE++F+ L+ IQ N +KNR IIP E +RV I G E
Sbjct: 2016 GPAGKTKLEKQFQLLSQSNIQQSDYSAALKQCNREKNRTSSIIPVERSRVGISSLSG-EG 2074
Query: 586 TDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQ 645
TDY+NAS+I GY Q + +I +Q PLLHTI+DFWRMIW+ + +VM+ + + +++
Sbjct: 2075 TDYINASYIMGYYQSNEFIITQHPLLHTIKDFWRMIWDHNAQLVVMIPDGQNMAEDEFV- 2133
Query: 646 YWPS-DGLVSYGDITVELKKEE-EC----ESYTVRDLLVTNTRENKSRQIRQFHFHGWPE 699
YWP+ D ++ V L EE +C E ++D ++ T+++ ++R F WP
Sbjct: 2134 YWPNKDEPINCESFKVTLMAEEHKCLSNEEKLIIQDFILEATQDDYVLEVRHFQCPKWPN 2193
Query: 700 VGIP-SDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGIL 758
P S +IS+I K++ + + P+ VH G GTFCAL+T++ +++ E +
Sbjct: 2194 PDSPISKTFELISVI----KEEAANRDGPMIVHDEHGGVTAGTFCALTTLMHQLEKENSV 2249
Query: 759 DVFQTVKSLRLQRPHMVQTLEQYEFCYKVV 788
DV+Q K + L RP + +EQY+F YKV+
Sbjct: 2250 DVYQVAKMINLMRPGVFADIEQYQFLYKVI 2279
Score = 201 bits (510), Expect = 3e-51
Identities = 105/282 (37%), Positives = 167/282 (59%), Gaps = 19/282 (6%)
Query: 529 SNNGLEEEFKKLTSI--KIQNDKMRTG------NLPANMKKNRVLQIIPYEFNRVIIP-- 578
+++G EEF+ L ++Q+ + G N P N KNR + I+ Y+ +RV +
Sbjct: 1713 ASSGFTEEFETLKEFYQEVQSCTVDLGITADSSNHPDNKHKNRYINIVAYDHSRVKLAQL 1772
Query: 579 VKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEER 638
++ + TDY+NA+++DGY + +YIA+QGPL T EDFWRMIWE IVM+T L E+
Sbjct: 1773 AEKDGKLTDYINANYVDGYNRPKAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEK 1832
Query: 639 GQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQ--------IR 690
G+ KC QYWP+DG YG+ V K + YTVR+ + NT+ K Q +
Sbjct: 1833 GRRKCDQYWPADGSEEYGNFLVTQKSVQVLAYYTVRNFTLRNTKIKKGSQKGRPSGRVVT 1892
Query: 691 QFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLE 750
Q+H+ WP++G+P +++ + ++ + P+ VHCSAG GRTGT+ L ++L+
Sbjct: 1893 QYHYTQWPDMGVPEYSLPVLTFVRKAAYAKRHAVG-PVVVHCSAGVGRTGTYIVLDSMLQ 1951
Query: 751 RVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI 792
+++ EG +++F +K +R QR ++VQT EQY F + + E I
Sbjct: 1952 QIQHEGTVNIFGFLKHIRSQRNYLVQTEEQYVFIHDTLVEAI 1993
Score = 116 bits (291), Expect = 7e-26
Identities = 82/269 (30%), Positives = 130/269 (48%), Gaps = 12/269 (4%)
Query: 254 QATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAA 313
Q+ AA K+ N+EKNR +I+P + SRV ++ + G +DYINAS+I GY + N+FI
Sbjct: 2037 QSDYSAALKQCNREKNRTSSIIPVERSRVGISSLSG-EGTDYINASYIMGYYQSNEFIIT 2095
Query: 314 QGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQ----GCWTYGNIRVSV 369
Q P T+ DFWRMIW+ N +VM+ + + E + YWP++ C ++ + +
Sbjct: 2096 QHPLLHTIKDFWRMIWDHNAQLVVMIPDGQNMAEDEFV-YWPNKDEPINCESF-KVTLMA 2153
Query: 370 EDVTVLVDYTVRKFCIQQ-VGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVK 428
E+ L + K IQ + + T + F WP+ P + L + K +
Sbjct: 2154 EEHKCLSNE--EKLIIQDFILEATQDDYVLEVRHFQCPKWPNPDSPISKTFELISVIKEE 2211
Query: 429 ACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTD 488
A N G ++VH G GTF + ++ + E VDVY I R +
Sbjct: 2212 AANRD--GPMIVHDEHGGVTAGTFCALTTLMHQLEKENSVDVYQVAKMINLMRPGVFADI 2269
Query: 489 MQYVFIYQALLEHYLYGDTELEVTSLETH 517
QY F+Y+ +L E TSL+++
Sbjct: 2270 EQYQFLYKVILSLVSTRQEENPSTSLDSN 2298
>gi|110735404 protein tyrosine phosphatase, receptor type, U isoform 1
precursor [Homo sapiens]
Length = 1436
Score = 404 bits (1039), Expect = e-112
Identities = 214/586 (36%), Positives = 334/586 (56%), Gaps = 17/586 (2%)
Query: 214 TNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVN 273
T + +P + V L + IN+ + F++E+ + +A K++ + +R
Sbjct: 857 TGQLHPAVRVADLLQHINQMKTAEGYGFKQEYESF-----FEGWDATKKKDKVKGSRQEP 911
Query: 274 ILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNT 333
+ YD RV L P+ G P++DYINA++I+GY N FIA QGPK E V DFWRM+W+++
Sbjct: 912 MPAYDRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHC 971
Query: 334 ATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTN 393
++IVM+T L E KC++YWP+ TYG+I++ + L +Y VR F +++ G
Sbjct: 972 SSIVMITKLVEVGRVKCSRYWPEDSD-TYGDIKIMLVKTETLAEYVVRTFALERRGYSAR 1030
Query: 394 RKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFV 453
+ + QFHFT+WP+ GVP+ G+L F+++VKA P AG IV+HCSAG GRTG ++
Sbjct: 1031 HE----VRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPIVIHCSAGTGRTGCYI 1086
Query: 454 VIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTS 513
V+D MLDM E VD+Y V + ++R M+QT+ QY+FI+ A+LE L G+T + V+
Sbjct: 1087 VLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACLCGETTIPVSE 1146
Query: 514 LETHLQKIYNKIPGTSNNGLEEEFKKLTSI--KIQNDKMRTGNLPANMKKNRVLQIIPYE 571
+ +++ P ++++ L EEF+ L S+ + ++ LP N KNR + ++P +
Sbjct: 1147 FKATYKEMIRIDPQSNSSQLREEFQTLNSVTPPLDVEECSIALLPRNRDKNRSMDVLPPD 1206
Query: 572 FNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVM 631
+ G+ N +Y+NA+ D Y + ++I + PL T DFWR+++++ SIVM
Sbjct: 1207 RCLPFLISTDGDSN-NYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVM 1265
Query: 632 LTELEERGQE-KCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQ-- 688
L +L + C QYWP G YG + VE E R V N +
Sbjct: 1266 LNQLNQSNSAWPCLQYWPEPGRQQYGLMEVEFMSGTADEDLVARVFRVQNISRLQEGHLL 1325
Query: 689 IRQFHFHGWPEV-GIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALST 747
+R F F W P K + ++A V K Q +SG+ VHC G GR+GTFCA +T
Sbjct: 1326 VRHFQFLRWSAYRDTPDSKKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGTFCACAT 1385
Query: 748 VLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID 793
VLE ++ ++DVF K+LR +P+MV+T++QY FCY V EY++
Sbjct: 1386 VLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLE 1431
>gi|110735402 protein tyrosine phosphatase, receptor type, U isoform 3
precursor [Homo sapiens]
Length = 1446
Score = 404 bits (1039), Expect = e-112
Identities = 214/586 (36%), Positives = 334/586 (56%), Gaps = 17/586 (2%)
Query: 214 TNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVN 273
T + +P + V L + IN+ + F++E+ + +A K++ + +R
Sbjct: 867 TGQLHPAVRVADLLQHINQMKTAEGYGFKQEYESF-----FEGWDATKKKDKVKGSRQEP 921
Query: 274 ILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNT 333
+ YD RV L P+ G P++DYINA++I+GY N FIA QGPK E V DFWRM+W+++
Sbjct: 922 MPAYDRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHC 981
Query: 334 ATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTN 393
++IVM+T L E KC++YWP+ TYG+I++ + L +Y VR F +++ G
Sbjct: 982 SSIVMITKLVEVGRVKCSRYWPEDSD-TYGDIKIMLVKTETLAEYVVRTFALERRGYSAR 1040
Query: 394 RKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFV 453
+ + QFHFT+WP+ GVP+ G+L F+++VKA P AG IV+HCSAG GRTG ++
Sbjct: 1041 HE----VRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPIVIHCSAGTGRTGCYI 1096
Query: 454 VIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTS 513
V+D MLDM E VD+Y V + ++R M+QT+ QY+FI+ A+LE L G+T + V+
Sbjct: 1097 VLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACLCGETTIPVSE 1156
Query: 514 LETHLQKIYNKIPGTSNNGLEEEFKKLTSI--KIQNDKMRTGNLPANMKKNRVLQIIPYE 571
+ +++ P ++++ L EEF+ L S+ + ++ LP N KNR + ++P +
Sbjct: 1157 FKATYKEMIRIDPQSNSSQLREEFQTLNSVTPPLDVEECSIALLPRNRDKNRSMDVLPPD 1216
Query: 572 FNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVM 631
+ G+ N +Y+NA+ D Y + ++I + PL T DFWR+++++ SIVM
Sbjct: 1217 RCLPFLISTDGDSN-NYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVM 1275
Query: 632 LTELEERGQE-KCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQ-- 688
L +L + C QYWP G YG + VE E R V N +
Sbjct: 1276 LNQLNQSNSAWPCLQYWPEPGRQQYGLMEVEFMSGTADEDLVARVFRVQNISRLQEGHLL 1335
Query: 689 IRQFHFHGWPEV-GIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALST 747
+R F F W P K + ++A V K Q +SG+ VHC G GR+GTFCA +T
Sbjct: 1336 VRHFQFLRWSAYRDTPDSKKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGTFCACAT 1395
Query: 748 VLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID 793
VLE ++ ++DVF K+LR +P+MV+T++QY FCY V EY++
Sbjct: 1396 VLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLE 1441
>gi|194097398 protein tyrosine phosphatase, receptor type, G precursor
[Homo sapiens]
Length = 1445
Score = 403 bits (1035), Expect = e-112
Identities = 239/678 (35%), Positives = 373/678 (55%), Gaps = 53/678 (7%)
Query: 153 IAVMVALSSLLVIVFIIIVLYML------------RFKKYKQAGSHSNS-----FRLSNG 195
+ V+ AL+ + +I+ I +++Y RF++ +G F+ ++
Sbjct: 741 LIVVSALTFVCLILLIAVLVYWRGCNKIKSKGFPRRFREVPSSGERGEKGSRKCFQTAHF 800
Query: 196 RTED------VEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALP 249
ED V +S+P++ +PV + + I +++ F E+F +
Sbjct: 801 YVEDSSSPRVVPNESIPIIPIPDDMEA----IPVKQFVKHIGELYSNNQHGFSEDFEEVQ 856
Query: 250 ACP--IQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPD--SDYINASFINGYQ 305
C + T E ++ ENK KNRY+NIL YDHSRV L P+ G SDYINA++++GY
Sbjct: 857 RCTADMNITAEHSNHPENKHKNRYINILAYDHSRVKLRPLPGKDSKHSDYINANYVDGYN 916
Query: 306 EKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNI 365
+ +IA QGP + T DFWRMIWEQNT IVM+TNL E+ KC QYWP + YGNI
Sbjct: 917 KAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWPTENSEEYGNI 976
Query: 366 RVSVEDVTVLVDYTVRKFCIQ-------QVGDMTNRKPQRLITQFHFTSWPDFGVPFTPI 418
V+++ + YTVR+F I+ Q G+ R+ +R++ Q+H+T WPD GVP +
Sbjct: 977 IVTLKSTKIHACYTVRRFSIRNTKVKKGQKGNPKGRQNERVVIQYHYTQWPDMGVPEYAL 1036
Query: 419 GMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIR 478
+L F+++ A G ++VHCSAGVGRTGT++VID+ML + + V+V GF+ IR
Sbjct: 1037 PVLTFVRRSSAARMPETGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIR 1096
Query: 479 AQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGT-SNNGLEEEF 537
QR +VQT+ QY+FI+ ALLE L +TE+ L +++ I IPG LE++F
Sbjct: 1097 TQRNYLVQTEEQYIFIHDALLEAILGKETEVSSNQLHSYVNSIL--IPGVGGKTRLEKQF 1154
Query: 538 KKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGY 597
K +T + + + N +KNR ++P E RV + G + TDY+NAS+I GY
Sbjct: 1155 KLVTQCNAKYVECFSAQKECNKEKNRNSSVVPSERARVGLAPLPGMKGTDYINASYIMGY 1214
Query: 598 RQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPS-DGLVSYG 656
+ + +I +Q PL HT +DFWRMIW+ + IVML + + +++ YWPS + ++
Sbjct: 1215 YRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFV-YWPSREESMNCE 1273
Query: 657 DITVEL-KKEEEC----ESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIP-SDGKGMI 710
TV L K+ C E + D ++ T+++ ++R F WP P S +I
Sbjct: 1274 AFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELI 1333
Query: 711 SIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQ 770
++I K++ + + P VH GA G CAL+T+ ++++ E +DVFQ K + L
Sbjct: 1334 NVI----KEEALTRDGPTIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMINLM 1389
Query: 771 RPHMVQTLEQYEFCYKVV 788
RP + +EQY+F YK +
Sbjct: 1390 RPGVFTDIEQYQFIYKAM 1407
Score = 195 bits (495), Expect = 2e-49
Identities = 103/298 (34%), Positives = 168/298 (56%), Gaps = 19/298 (6%)
Query: 509 LEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQ-NDKMRTGNLPANMKKNRVLQI 567
+ V H+ ++Y+ + +G E+F+++ N N P N KNR + I
Sbjct: 828 IPVKQFVKHIGELYSN----NQHGFSEDFEEVQRCTADMNITAEHSNHPENKHKNRYINI 883
Query: 568 IPYEFNRVIIPVKRGEEN--TDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWK 625
+ Y+ +RV + G+++ +DY+NA+++DGY + +YIA+QGPL T EDFWRMIWE
Sbjct: 884 LAYDHSRVKLRPLPGKDSKHSDYINANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQN 943
Query: 626 SCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENK 685
+ IVM+T L E+G+ KC QYWP++ YG+I V LK + YTVR + NT+ K
Sbjct: 944 TGIIVMITNLVEKGRRKCDQYWPTENSEEYGNIIVTLKSTKIHACYTVRRFSIRNTKVKK 1003
Query: 686 S-----------RQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSA 734
R + Q+H+ WP++G+P +++ + + P+ VHCSA
Sbjct: 1004 GQKGNPKGRQNERVVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPETG-PVLVHCSA 1062
Query: 735 GAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI 792
G GRTGT+ + ++L+++K + ++V +K +R QR ++VQT EQY F + + E I
Sbjct: 1063 GVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAI 1120
Score = 113 bits (283), Expect = 6e-25
Identities = 77/264 (29%), Positives = 121/264 (45%), Gaps = 14/264 (5%)
Query: 243 EEFNALPACPIQ-ATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFI 301
++F + C + C +A KE NKEKNR +++P + +RV L P+ G+ +DYINAS+I
Sbjct: 1152 KQFKLVTQCNAKYVECFSAQKECNKEKNRNSSVVPSERARVGLAPLPGMKGTDYINASYI 1211
Query: 302 NGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQ---- 357
GY N+FI Q P T DFWRMIW+ N IVM+ + + E + YWP +
Sbjct: 1212 MGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFV-YWPSREESM 1270
Query: 358 GCWTYGNIRVSVEDVTVLVD--YTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPF 415
C + +S + + + + + F ++ D + + F WP+ P
Sbjct: 1271 NCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLE----VRHFQCPKWPNPDAPI 1326
Query: 416 TPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVS 475
+ L + K +A G +VH G G + + + E VDV+
Sbjct: 1327 SSTFELINVIKEEALTRD--GPTIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAK 1384
Query: 476 RIRAQRCQMVQTDMQYVFIYQALL 499
I R + QY FIY+A+L
Sbjct: 1385 MINLMRPGVFTDIEQYQFIYKAML 1408
>gi|110735406 protein tyrosine phosphatase, receptor type, U isoform 2
precursor [Homo sapiens]
Length = 1442
Score = 398 bits (1022), Expect = e-110
Identities = 214/592 (36%), Positives = 334/592 (56%), Gaps = 23/592 (3%)
Query: 214 TNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVN 273
T + +P + V L + IN+ + F++E+ + +A K++ + +R
Sbjct: 857 TGQLHPAVRVADLLQHINQMKTAEGYGFKQEYESF-----FEGWDATKKKDKVKGSRQEP 911
Query: 274 ILPYDHSRVHLTPVEGVPDSDYINASFIN------GYQEKNKFIAAQGPKEETVNDFWRM 327
+ YD RV L P+ G P++DYINA++I+ GY N FIA QGPK E V DFWRM
Sbjct: 912 MPAYDRHRVKLHPMLGDPNADYINANYIDIRINREGYHRSNHFIATQGPKPEMVYDFWRM 971
Query: 328 IWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQ 387
+W+++ ++IVM+T L E KC++YWP+ TYG+I++ + L +Y VR F +++
Sbjct: 972 VWQEHCSSIVMITKLVEVGRVKCSRYWPEDSD-TYGDIKIMLVKTETLAEYVVRTFALER 1030
Query: 388 VGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVG 447
G + + QFHFT+WP+ GVP+ G+L F+++VKA P AG IV+HCSAG G
Sbjct: 1031 RGYSARHE----VRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPIVIHCSAGTG 1086
Query: 448 RTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDT 507
RTG ++V+D MLDM E VD+Y V + ++R M+QT+ QY+FI+ A+LE L G+T
Sbjct: 1087 RTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACLCGET 1146
Query: 508 ELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSI--KIQNDKMRTGNLPANMKKNRVL 565
+ V+ + +++ P ++++ L EEF+ L S+ + ++ LP N KNR +
Sbjct: 1147 TIPVSEFKATYKEMIRIDPQSNSSQLREEFQTLNSVTPPLDVEECSIALLPRNRDKNRSM 1206
Query: 566 QIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWK 625
++P + + G+ N +Y+NA+ D Y + ++I + PL T DFWR+++++
Sbjct: 1207 DVLPPDRCLPFLISTDGDSN-NYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYG 1265
Query: 626 SCSIVMLTELEERGQE-KCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTREN 684
SIVML +L + C QYWP G YG + VE E R V N
Sbjct: 1266 CTSIVMLNQLNQSNSAWPCLQYWPEPGRQQYGLMEVEFMSGTADEDLVARVFRVQNISRL 1325
Query: 685 KSRQ--IRQFHFHGWPEV-GIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGT 741
+ +R F F W P K + ++A V K Q +SG+ VHC G GR+GT
Sbjct: 1326 QEGHLLVRHFQFLRWSAYRDTPDSKKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGT 1385
Query: 742 FCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID 793
FCA +TVLE ++ ++DVF K+LR +P+MV+T++QY FCY V EY++
Sbjct: 1386 FCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLE 1437
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,225,760
Number of Sequences: 37866
Number of extensions: 1374144
Number of successful extensions: 6047
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 130
Number of HSP's successfully gapped in prelim test: 58
Number of HSP's that attempted gapping in prelim test: 4218
Number of HSP's gapped (non-prelim): 904
length of query: 802
length of database: 18,247,518
effective HSP length: 110
effective length of query: 692
effective length of database: 14,082,258
effective search space: 9744922536
effective search space used: 9744922536
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.