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Search of human proteins with 4505817
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I,
beta isoform 2 [Homo sapiens]
(540 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, be... 1080 0.0
gi|31317309 phosphatidylinositol-4-phosphate 5-kinase, type I, g... 652 0.0
gi|208431778 phosphatidylinositol-4-phosphate 5-kinase, type I, ... 603 e-173
gi|4505815 phosphatidylinositol-4-phosphate 5-kinase, type I, al... 603 e-173
gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I, ... 591 e-169
gi|208431774 phosphatidylinositol-4-phosphate 5-kinase, type I, ... 548 e-156
gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, b... 180 3e-45
gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type II,... 162 6e-40
gi|226371737 phosphatidylinositol-5-phosphate 4-kinase, type II,... 162 6e-40
gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II, a... 161 2e-39
gi|226371741 phosphatidylinositol-5-phosphate 4-kinase, type II,... 154 2e-37
gi|226371743 phosphatidylinositol-5-phosphate 4-kinase, type II,... 135 9e-32
gi|206725454 phosphatidylinositol-4-phosphate 5-kinase-like 1 is... 100 3e-21
gi|27735085 phosphatidylinositol-4-phosphate 5-kinase-like 1 iso... 57 6e-08
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 56 7e-08
gi|222537754 hypothetical protein LOC375337 [Homo sapiens] 33 0.86
gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-l... 30 4.3
gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-l... 30 5.6
gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens] 30 5.6
gi|110347463 human immunodeficiency virus type I enhancer bindin... 30 5.6
gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo sapi... 30 7.3
gi|34452707 bromodomain containing 8 isoform 2 [Homo sapiens] 30 7.3
gi|113425121 PREDICTED: similar to Golgin subfamily A member 8-l... 29 9.6
gi|113425119 PREDICTED: similar to golgi autoantigen, golgin sub... 29 9.6
gi|19923233 sterol carrier protein 2 isoform 1 proprotein [Homo ... 29 9.6
gi|55956775 sterol carrier protein 2 isoform 2 [Homo sapiens] 29 9.6
>gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, beta
isoform 2 [Homo sapiens]
Length = 540
Score = 1080 bits (2792), Expect = 0.0
Identities = 540/540 (100%), Positives = 540/540 (100%)
Query: 1 MSSAAENGEAAPGKQNEEKTYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVV 60
MSSAAENGEAAPGKQNEEKTYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVV
Sbjct: 1 MSSAAENGEAAPGKQNEEKTYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVV 60
Query: 61 ESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNP 120
ESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNP
Sbjct: 61 ESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNP 120
Query: 121 GASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGG 180
GASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGG
Sbjct: 121 GASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGG 180
Query: 181 INIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYF 240
INIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYF
Sbjct: 181 INIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYF 240
Query: 241 DTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQ 300
DTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQ
Sbjct: 241 DTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQ 300
Query: 301 KVLYSTAMESIQGPGKSGDGIITENPDTMGGIPAKSHRGEKLLLFMGIIDILQSYRLMKK 360
KVLYSTAMESIQGPGKSGDGIITENPDTMGGIPAKSHRGEKLLLFMGIIDILQSYRLMKK
Sbjct: 301 KVLYSTAMESIQGPGKSGDGIITENPDTMGGIPAKSHRGEKLLLFMGIIDILQSYRLMKK 360
Query: 361 LEHSWKALVYDGDTVSVHRPSFYADRFLKFMNSRVFKKIQALKASPSKKRCNSIAALKAT 420
LEHSWKALVYDGDTVSVHRPSFYADRFLKFMNSRVFKKIQALKASPSKKRCNSIAALKAT
Sbjct: 361 LEHSWKALVYDGDTVSVHRPSFYADRFLKFMNSRVFKKIQALKASPSKKRCNSIAALKAT 420
Query: 421 SQEIVSSISQEWKDEKRDLLTEGQSFSSLDEEALGSRHRPDLVPSTPSLFEAASLATTIS 480
SQEIVSSISQEWKDEKRDLLTEGQSFSSLDEEALGSRHRPDLVPSTPSLFEAASLATTIS
Sbjct: 421 SQEIVSSISQEWKDEKRDLLTEGQSFSSLDEEALGSRHRPDLVPSTPSLFEAASLATTIS 480
Query: 481 SSSLYVNEHYPHDRPTLYSNSKGLPSSSTFTLEEGTIYLTAEPNTLEVQDDNASVLDVYL 540
SSSLYVNEHYPHDRPTLYSNSKGLPSSSTFTLEEGTIYLTAEPNTLEVQDDNASVLDVYL
Sbjct: 481 SSSLYVNEHYPHDRPTLYSNSKGLPSSSTFTLEEGTIYLTAEPNTLEVQDDNASVLDVYL 540
>gi|31317309 phosphatidylinositol-4-phosphate 5-kinase, type I,
gamma [Homo sapiens]
Length = 668
Score = 652 bits (1681), Expect = 0.0
Identities = 332/482 (68%), Positives = 394/482 (81%), Gaps = 13/482 (2%)
Query: 18 EKTYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHH 77
E TYKKT SS +KGAIQLGIGYTVG+L+SKPERDVLMQDFYVVES+F PSEGSNLTPAHH
Sbjct: 68 ETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHH 127
Query: 78 YPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFVTSDDEFII 137
+ DFRFKTYAP+AFRYFRELFGI+PDDYLYS+C+EPLIELSNPGASGSLF+VTSDDEFII
Sbjct: 128 FQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFII 187
Query: 138 KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGGINIRIVVMNNVLPRSMR 197
KTV HKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYC+QSGG NIR+VVMNN+LPR ++
Sbjct: 188 KTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVK 247
Query: 198 MHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCR 257
MH +DLKGSTYKRRAS+KE+EKS PT+KDLDF+QDM EGL D +T++AL+KTLQRDC
Sbjct: 248 MHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVKTLQRDCL 307
Query: 258 VLESFKIMDYSLLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYSTAMESIQGPGKS 317
VLESFKIMDYSLLLG+H +D +E++ + Q+ D KR QK LYSTAMESIQG
Sbjct: 308 VLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMESIQGGAAR 367
Query: 318 GDGIITENPDTMGGIPAKSHRGEKLLLFMGIIDILQSYRLMKKLEHSWKALVYDGDTVSV 377
G+ I E+ DTMGGIPA + RGE+LLL +GIIDILQSYR +KKLEH+WKALV+DGDTVSV
Sbjct: 368 GEAI--ESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDGDTVSV 425
Query: 378 HRPSFYADRFLKFMNSRVFKKIQALKASPSKK-RCNSIAALKATSQEIVSSISQ--EWKD 434
HRPSFYA+RF KFM++ VF+K +LK+SPSKK R ++ A+K S SQ ++
Sbjct: 426 HRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQIPSERE 485
Query: 435 EKRDLLTEGQSFSSLDEEALGSRHRPDLVPSTPSLFE---AASLATTISSSSLYVNEHYP 491
E + L +S+ +L++E RPDL+P TP FE AS+ATT+SS+SL + E P
Sbjct: 486 EAQYDLRGARSYPTLEDEG-----RPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSP 540
Query: 492 HD 493
+
Sbjct: 541 SE 542
>gi|208431778 phosphatidylinositol-4-phosphate 5-kinase, type I,
alpha isoform 1 [Homo sapiens]
Length = 562
Score = 603 bits (1556), Expect = e-173
Identities = 315/460 (68%), Positives = 363/460 (78%), Gaps = 18/460 (3%)
Query: 18 EKTYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHH 77
E TYKKT SSA+KGAIQLGI +TVG+L++KPERDVLMQDFYVVES+F PSEGSNLTPAHH
Sbjct: 74 ETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHH 133
Query: 78 YPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFVTSDDEFII 137
Y DFRFKTYAP+AFRYFRELFGI+PDDYLYS+CSEPLIEL + GASGSLF+V+SDDEFII
Sbjct: 134 YNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFII 193
Query: 138 KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGGINIRIVVMNNVLPRSMR 197
KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYC+Q+GG NIRIVVMNN+LPRS++
Sbjct: 194 KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVK 253
Query: 198 MHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCR 257
MH YDLKGSTYKRRAS+KEREK PTFKDLDFLQD+ +GL+ D + YNAL KTLQRDC
Sbjct: 254 MHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCL 313
Query: 258 VLESFKIMDYSLLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYSTAMESIQGPGKS 317
VL+SFKIMDYSLL+ IH +DH+ +E Q D +R QK LYSTAMESIQG +
Sbjct: 314 VLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQGEARR 373
Query: 318 GDGIITENPDTMGGIPAKSHRGEKLLLFMGIIDILQSYRLMKKLEHSWKALVYDGDTVSV 377
G + E D MGGIPA++ +GE+LLL++GIIDILQSYR +KKLEHSWKALV+DGDTVSV
Sbjct: 374 GGTM--ETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSV 431
Query: 378 HRPSFYADRFLKFMNSRVFKKIQALKASPSKK-RCNSIAALKATSQ-----EIVSSISQE 431
HRP FYA+RF +FM + VFKKI LK SPSKK R S + +A S S+S E
Sbjct: 432 HRPGFYAERFQRFMCNTVFKKI-PLKPSPSKKFRSGSSFSRRAGSSGNSCITYQPSVSGE 490
Query: 432 WKDEKRDLLTEGQSFSSLDEEALGSRHRPDLVPSTPSLFE 471
K Q + + E RPD++P TP L E
Sbjct: 491 HK---------AQVTTKAEVEPGVHLGRPDVLPQTPPLEE 521
>gi|4505815 phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
isoform 2 [Homo sapiens]
Length = 549
Score = 603 bits (1556), Expect = e-173
Identities = 315/460 (68%), Positives = 363/460 (78%), Gaps = 18/460 (3%)
Query: 18 EKTYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHH 77
E TYKKT SSA+KGAIQLGI +TVG+L++KPERDVLMQDFYVVES+F PSEGSNLTPAHH
Sbjct: 61 ETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHH 120
Query: 78 YPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFVTSDDEFII 137
Y DFRFKTYAP+AFRYFRELFGI+PDDYLYS+CSEPLIEL + GASGSLF+V+SDDEFII
Sbjct: 121 YNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFII 180
Query: 138 KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGGINIRIVVMNNVLPRSMR 197
KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYC+Q+GG NIRIVVMNN+LPRS++
Sbjct: 181 KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVK 240
Query: 198 MHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCR 257
MH YDLKGSTYKRRAS+KEREK PTFKDLDFLQD+ +GL+ D + YNAL KTLQRDC
Sbjct: 241 MHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCL 300
Query: 258 VLESFKIMDYSLLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYSTAMESIQGPGKS 317
VL+SFKIMDYSLL+ IH +DH+ +E Q D +R QK LYSTAMESIQG +
Sbjct: 301 VLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQGEARR 360
Query: 318 GDGIITENPDTMGGIPAKSHRGEKLLLFMGIIDILQSYRLMKKLEHSWKALVYDGDTVSV 377
G + E D MGGIPA++ +GE+LLL++GIIDILQSYR +KKLEHSWKALV+DGDTVSV
Sbjct: 361 GGTM--ETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSV 418
Query: 378 HRPSFYADRFLKFMNSRVFKKIQALKASPSKK-RCNSIAALKATSQ-----EIVSSISQE 431
HRP FYA+RF +FM + VFKKI LK SPSKK R S + +A S S+S E
Sbjct: 419 HRPGFYAERFQRFMCNTVFKKI-PLKPSPSKKFRSGSSFSRRAGSSGNSCITYQPSVSGE 477
Query: 432 WKDEKRDLLTEGQSFSSLDEEALGSRHRPDLVPSTPSLFE 471
K Q + + E RPD++P TP L E
Sbjct: 478 HK---------AQVTTKAEVEPGVHLGRPDVLPQTPPLEE 508
>gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I,
alpha isoform 4 [Homo sapiens]
Length = 500
Score = 591 bits (1524), Expect = e-169
Identities = 290/382 (75%), Positives = 331/382 (86%), Gaps = 2/382 (0%)
Query: 18 EKTYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHH 77
E TYKKT SSA+KGAIQLGI +TVG+L++KPERDVLMQDFYVVES+F PSEGSNLTPAHH
Sbjct: 61 ETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHH 120
Query: 78 YPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFVTSDDEFII 137
Y DFRFKTYAP+AFRYFRELFGI+PDDYLYS+CSEPLIEL + GASGSLF+V+SDDEFII
Sbjct: 121 YNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFII 180
Query: 138 KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGGINIRIVVMNNVLPRSMR 197
KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYC+Q+GG NIRIVVMNN+LPRS++
Sbjct: 181 KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVK 240
Query: 198 MHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCR 257
MH YDLKGSTYKRRAS+KEREK PTFKDLDFLQD+ +GL+ D + YNAL KTLQRDC
Sbjct: 241 MHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCL 300
Query: 258 VLESFKIMDYSLLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYSTAMESIQGPGKS 317
VL+SFKIMDYSLL+ IH +DH+ +E Q D +R QK LYSTAMESIQG +
Sbjct: 301 VLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQGEARR 360
Query: 318 GDGIITENPDTMGGIPAKSHRGEKLLLFMGIIDILQSYRLMKKLEHSWKALVYDGDTVSV 377
G + E D MGGIPA++ +GE+LLL++GIIDILQSYR +KKLEHSWKALV+DGDTVSV
Sbjct: 361 GGTM--ETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSV 418
Query: 378 HRPSFYADRFLKFMNSRVFKKI 399
HRP FYA+RF +FM + VFKKI
Sbjct: 419 HRPGFYAERFQRFMCNTVFKKI 440
>gi|208431774 phosphatidylinositol-4-phosphate 5-kinase, type I,
alpha isoform 3 [Homo sapiens]
Length = 522
Score = 548 bits (1412), Expect = e-156
Identities = 293/460 (63%), Positives = 338/460 (73%), Gaps = 46/460 (10%)
Query: 18 EKTYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHH 77
E TYKKT SSA+KGAIQLGI +TVG+L++KPERDVLMQDFYVVES+F PSEGSNLTPAHH
Sbjct: 62 ETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHH 121
Query: 78 YPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFVTSDDEFII 137
Y DFRFKTYAP+AFRYFRELFGI+PDDYLYS+CSEPLIEL + GASGSLF+V+SDDEFII
Sbjct: 122 YNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFII 181
Query: 138 KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGGINIRIVVMNNVLPRSMR 197
KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYC+Q+GG NIRIVVMNN+LPRS++
Sbjct: 182 KTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVK 241
Query: 198 MHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCR 257
MH YDLKGSTYKRRAS+KEREK PTFKDLDFLQD+ +GL+ D + YNAL KTLQRDC
Sbjct: 242 MHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCL 301
Query: 258 VLESFKIMDYSLLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYSTAMESIQGPGKS 317
VL+SFKIMDYSLL+ IH +DH+ +E Q D +R QK LYSTAMESIQG +
Sbjct: 302 VLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQGEARR 361
Query: 318 GDGIITENPDTMGGIPAKSHRGEKLLLFMGIIDILQSYRLMKKLEHSWKALVYDGDTVSV 377
G + T++ + +KKLEHSWKALV+DGDTVSV
Sbjct: 362 GGTMETDD------------------------------QFVKKLEHSWKALVHDGDTVSV 391
Query: 378 HRPSFYADRFLKFMNSRVFKKIQALKASPSKK-RCNSIAALKATSQ-----EIVSSISQE 431
HRP FYA+RF +FM + VFKKI LK SPSKK R S + +A S S+S E
Sbjct: 392 HRPGFYAERFQRFMCNTVFKKI-PLKPSPSKKFRSGSSFSRRAGSSGNSCITYQPSVSGE 450
Query: 432 WKDEKRDLLTEGQSFSSLDEEALGSRHRPDLVPSTPSLFE 471
K Q + + E RPD++P TP L E
Sbjct: 451 HK---------AQVTTKAEVEPGVHLGRPDVLPQTPPLEE 481
>gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, beta
[Homo sapiens]
Length = 416
Score = 180 bits (457), Expect = 3e-45
Identities = 135/406 (33%), Positives = 198/406 (48%), Gaps = 29/406 (7%)
Query: 11 APGKQNEEKTYKK----------TASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVV 60
AP ++ KT KK AS I + G+ +T+ L++ P +LM D +
Sbjct: 14 APLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKA 73
Query: 61 ESVFLPSEGSNLTPAHHYPD-FRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSN 119
S ++L + P F+FK Y P+ FR RE FGI DY S+ I +
Sbjct: 74 YSKI--KVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDS 131
Query: 120 PGASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCMQS 178
G G+ F T D F+IKTV ++ + +L Y+ + + + TLLP+F G+Y +
Sbjct: 132 QGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTV 191
Query: 179 GGINIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGL 238
G+ +VV NV + +H YDLKGST R AS KE+ K PTFKD DFL + + L
Sbjct: 192 DGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNE-GQKL 250
Query: 239 YFDTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHFLDHSLKEK-EEETPQNVPDAKRT 297
+ E+ ++ L+RD L KIMDYSLL+GIH +D + +E+ E E + +
Sbjct: 251 HVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECEND 310
Query: 298 GMQKVL---YSTAMES----IQGPGKSGDGIITENPDTMGGIPAKSHRG--EKLLLFMGI 348
G+ L Y T +S + P G G + D KSH +K + FM I
Sbjct: 311 GVGGNLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYA---MKSHESSPKKEVYFMAI 367
Query: 349 IDILQSYRLMKKLEHSWKALVYD-GDTVSVHRPSFYADRFLKFMNS 393
IDIL Y KK H+ K + + G +S P Y+ RF +FM++
Sbjct: 368 IDILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSN 413
>gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform a [Homo sapiens]
Length = 421
Score = 162 bits (411), Expect = 6e-40
Identities = 128/415 (30%), Positives = 192/415 (46%), Gaps = 32/415 (7%)
Query: 3 SAAENGEAAPGKQNEEKTYKK----------TASSAIKGAIQLGIGYTVGNLTSKPERDV 52
SAA G PG KT KK A+ + G G+ +++ L+ P +
Sbjct: 12 SAATAGPG-PGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVM 70
Query: 53 LMQDFYVVESVFLPSEGSNLTPAHHYPD-FRFKTYAPLAFRYFRELFGIKPDDYLYSICS 111
L+ D + S ++L + P F+FK Y P FR R+ FGI DYL S+
Sbjct: 71 LLPDDFKASSKI--KVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYLVSLTR 128
Query: 112 EPLIELSNPGASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQ-NPRTLLPKF 170
P E + G+ G F ++ D +IK V ++ + L Y+ + + + TLLP+F
Sbjct: 129 NPPSE--SEGSDGR-FLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQF 185
Query: 171 YGLYCMQSGGINIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLDF 230
G+Y + + ++VM N+ + +H YDLKGS R AS KE+ K PT KD+DF
Sbjct: 186 LGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDF 245
Query: 231 LQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHFLDHSLKEKEEETPQN 290
L + ++ +Y E ++ L+RD L KIMDYSLLLGIH + E EEE P
Sbjct: 246 L-NKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRG-SEPEEEAPVR 303
Query: 291 VPDAKRTGMQKVLYSTAMESIQGPGKSGDGIITENPDTMG-----------GIPAKSHRG 339
+++ G + A+ G G G + +G I +
Sbjct: 304 EDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAP 363
Query: 340 EKLLLFMGIIDILQSYRLMKKLEHSWKALVYD-GDTVSVHRPSFYADRFLKFMNS 393
+K + FMG+IDIL Y KK H+ K + + G +S P YA RFL F+ +
Sbjct: 364 QKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITN 418
>gi|226371737 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform a [Homo sapiens]
Length = 421
Score = 162 bits (411), Expect = 6e-40
Identities = 128/415 (30%), Positives = 192/415 (46%), Gaps = 32/415 (7%)
Query: 3 SAAENGEAAPGKQNEEKTYKK----------TASSAIKGAIQLGIGYTVGNLTSKPERDV 52
SAA G PG KT KK A+ + G G+ +++ L+ P +
Sbjct: 12 SAATAGPG-PGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVM 70
Query: 53 LMQDFYVVESVFLPSEGSNLTPAHHYPD-FRFKTYAPLAFRYFRELFGIKPDDYLYSICS 111
L+ D + S ++L + P F+FK Y P FR R+ FGI DYL S+
Sbjct: 71 LLPDDFKASSKI--KVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYLVSLTR 128
Query: 112 EPLIELSNPGASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQ-NPRTLLPKF 170
P E + G+ G F ++ D +IK V ++ + L Y+ + + + TLLP+F
Sbjct: 129 NPPSE--SEGSDGR-FLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQF 185
Query: 171 YGLYCMQSGGINIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLDF 230
G+Y + + ++VM N+ + +H YDLKGS R AS KE+ K PT KD+DF
Sbjct: 186 LGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDF 245
Query: 231 LQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHFLDHSLKEKEEETPQN 290
L + ++ +Y E ++ L+RD L KIMDYSLLLGIH + E EEE P
Sbjct: 246 L-NKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRG-SEPEEEAPVR 303
Query: 291 VPDAKRTGMQKVLYSTAMESIQGPGKSGDGIITENPDTMG-----------GIPAKSHRG 339
+++ G + A+ G G G + +G I +
Sbjct: 304 EDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAP 363
Query: 340 EKLLLFMGIIDILQSYRLMKKLEHSWKALVYD-GDTVSVHRPSFYADRFLKFMNS 393
+K + FMG+IDIL Y KK H+ K + + G +S P YA RFL F+ +
Sbjct: 364 QKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITN 418
>gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II,
alpha [Homo sapiens]
Length = 406
Score = 161 bits (407), Expect = 2e-39
Identities = 112/379 (29%), Positives = 182/379 (48%), Gaps = 22/379 (5%)
Query: 25 ASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPD-FRF 83
AS + + G+ +++ L+ +LM D + S ++L + P F+F
Sbjct: 33 ASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKI--KVDNHLFNKENMPSHFKF 90
Query: 84 KTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFVTSDDEFIIKTVQHK 143
K Y P+ FR RE FGI D+ S+ + + SG+ F + D +IIKT+ +
Sbjct: 91 KEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIKTITSE 150
Query: 144 EAEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCMQSGGINIRIVVMNNVLPRSMRMHFTY 202
+ + +L Y+ + + + TLLP+F G+Y + G+ I ++V NV + ++ Y
Sbjct: 151 DVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRKY 210
Query: 203 DLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCRVLESF 262
DLKGST R AS KE+ K PT KD DF+ + + +Y D ++ L++D L
Sbjct: 211 DLKGSTVAREASDKEKAKELPTLKDNDFINE-GQKIYIDDNNKKVFLEKLKKDVEFLAQL 269
Query: 263 KIMDYSLLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYSTAMESIQGPGKSGDGII 322
K+MDYSLL+GIH ++ + +++E E +N D + G + P G+ +
Sbjct: 270 KLMDYSLLVGIHDVERA-EQEEVECEEN--DGEEEGESDGTHPVGTP----PDSPGNTLN 322
Query: 323 TENPDTMG---------GIPAKSHRGEKLLLFMGIIDILQSYRLMKKLEHSWKALVYD-G 372
+ P G GI + K + FM IIDIL Y KK H+ K + + G
Sbjct: 323 SSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAG 382
Query: 373 DTVSVHRPSFYADRFLKFM 391
+S P Y+ RFL F+
Sbjct: 383 AEISTVNPEQYSKRFLDFI 401
>gi|226371741 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform b [Homo sapiens]
Length = 403
Score = 154 bits (390), Expect = 2e-37
Identities = 124/414 (29%), Positives = 185/414 (44%), Gaps = 48/414 (11%)
Query: 3 SAAENGEAAPGKQNEEKTYKK----------TASSAIKGAIQLGIGYTVGNLTSKPERDV 52
SAA G PG KT KK A+ + G G+ +++ L+ P +
Sbjct: 12 SAATAGPG-PGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVM 70
Query: 53 LMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSE 112
L+ D + S + K Y P FR R+ FGI DYL S+
Sbjct: 71 LLPDDFKASS-------------------KIKEYCPQVFRNLRDRFGIDDQDYLVSLTRN 111
Query: 113 PLIELSNPGASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQ-NPRTLLPKFY 171
P E + G+ G F ++ D +IK V ++ + L Y+ + + + TLLP+F
Sbjct: 112 PPSE--SEGSDGR-FLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFL 168
Query: 172 GLYCMQSGGINIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFL 231
G+Y + + ++VM N+ + +H YDLKGS R AS KE+ K PT KD+DFL
Sbjct: 169 GMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFL 228
Query: 232 QDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHFLDHSLKEKEEETPQNV 291
+ ++ +Y E ++ L+RD L KIMDYSLLLGIH + E EEE P
Sbjct: 229 -NKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRG-SEPEEEAPVRE 286
Query: 292 PDAKRTGMQKVLYSTAMESIQGPGKSGDGIITENPDTMG-----------GIPAKSHRGE 340
+++ G + A+ G G G + +G I + +
Sbjct: 287 DESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQ 346
Query: 341 KLLLFMGIIDILQSYRLMKKLEHSWKALVYD-GDTVSVHRPSFYADRFLKFMNS 393
K + FMG+IDIL Y KK H+ K + + G +S P YA RFL F+ +
Sbjct: 347 KEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITN 400
>gi|226371743 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform c [Homo sapiens]
Length = 373
Score = 135 bits (340), Expect = 9e-32
Identities = 119/414 (28%), Positives = 172/414 (41%), Gaps = 78/414 (18%)
Query: 3 SAAENGEAAPGKQNEEKTYKK----------TASSAIKGAIQLGIGYTVGNLTSKPERDV 52
SAA G PG KT KK A+ + G G+ +++ L+ P +
Sbjct: 12 SAATAGPG-PGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVM 70
Query: 53 LMQDFYVVESVFLPSEGSNLTPAHHYPD-FRFKTYAPLAFRYFRELFGIKPDDYLYSICS 111
L+ D + S ++L + P F+FK Y P FR R+ FGI DYLY
Sbjct: 71 LLPDDFKASSKI--KVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYLY---- 124
Query: 112 EPLIELSNPGASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFY 171
I+K + TLLP+F
Sbjct: 125 ------------------------IVKC----------------------HGNTLLPQFL 138
Query: 172 GLYCMQSGGINIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFL 231
G+Y + + ++VM N+ + +H YDLKGS R AS KE+ K PT KD+DFL
Sbjct: 139 GMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFL 198
Query: 232 QDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHFLDHSLKEKEEETPQNV 291
+ ++ +Y E ++ L+RD L KIMDYSLLLGIH + E EEE P
Sbjct: 199 -NKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRG-SEPEEEAPVRE 256
Query: 292 PDAKRTGMQKVLYSTAMESIQGPGKSGDGIITENPDTMG-----------GIPAKSHRGE 340
+++ G + A+ G G G + +G I + +
Sbjct: 257 DESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQ 316
Query: 341 KLLLFMGIIDILQSYRLMKKLEHSWKALVYD-GDTVSVHRPSFYADRFLKFMNS 393
K + FMG+IDIL Y KK H+ K + + G +S P YA RFL F+ +
Sbjct: 317 KEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITN 370
>gi|206725454 phosphatidylinositol-4-phosphate 5-kinase-like 1
isoform 1 [Homo sapiens]
Length = 394
Score = 100 bits (249), Expect = 3e-21
Identities = 85/328 (25%), Positives = 146/328 (44%), Gaps = 30/328 (9%)
Query: 72 LTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSIC-SEPLIELSNPGASGSLFFVT 130
LT H F T A AF + R G+ +DY ++ P ++ + S + FF++
Sbjct: 88 LTQVHE--GFELGTLAGPAFAWLRRSLGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLS 145
Query: 131 SDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQ-SGGINIRIVVMN 189
D F +KT +E + L LP Y +L ++P +LL + G++ ++ G +VM
Sbjct: 146 HDQRFFLKTQGRREVQALLAHLPRYVQHLQRHPHSLLARLLGVHSLRVDRGKKTYFIVMQ 205
Query: 190 NVLPRSMRMHFTYDLKGSTYKRRAS-RKEREKSNPTFKDLDFLQDMHEGLYFDTETYNA- 247
+V + R+ YD+KG R E KDL+F +G + +
Sbjct: 206 SVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVLVLKDLNF-----QGKTINLGPQRSW 260
Query: 248 LMKTLQRDCRVLESFKIMDYSLLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYSTA 307
++ ++ D L ++DYSLL+ Q + + +R +++ TA
Sbjct: 261 FLRQMELDTTFLRELNVLDYSLLIAF---------------QRLHEDERGPGSSLIFRTA 305
Query: 308 MESIQGPGKSGDGIITENPDTMGGIPAKSH--RGEKLLLFMGIIDILQSYRLMKKLEHSW 365
S+QG +S + +N + P H G + F+G++D+ Y L K+LEH W
Sbjct: 306 -RSVQG-AQSPEESRAQNRRLLPDAPNALHILDGPEQRYFLGVVDLATVYGLRKRLEHLW 363
Query: 366 KALVYDGDTVSVHRPSFYADRFLKFMNS 393
K L Y G T S P+ YA R +++ +
Sbjct: 364 KTLRYPGRTFSTVSPARYARRLCQWVEA 391
>gi|27735085 phosphatidylinositol-4-phosphate 5-kinase-like 1
isoform 2 [Homo sapiens]
Length = 191
Score = 56.6 bits (135), Expect = 6e-08
Identities = 53/210 (25%), Positives = 90/210 (42%), Gaps = 26/210 (12%)
Query: 188 MNNVLPRSMRMHFTYDLKGSTYKRRAS-RKEREKSNPTFKDLDFLQDMHEGLYFDTETYN 246
M +V + R+ YD+KG R E KDL+F +G +
Sbjct: 1 MQSVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVLVLKDLNF-----QGKTINLGPQR 55
Query: 247 A-LMKTLQRDCRVLESFKIMDYSLLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYS 305
+ ++ ++ D L ++DYSLL+ Q + + +R +++
Sbjct: 56 SWFLRQMELDTTFLRELNVLDYSLLIAF---------------QRLHEDERGPGSSLIFR 100
Query: 306 TAMESIQGPGKSGDGIITENPDTMGGIPAKSH--RGEKLLLFMGIIDILQSYRLMKKLEH 363
TA S+QG +S + +N + P H G + F+G++D+ Y L K+LEH
Sbjct: 101 TA-RSVQG-AQSPEESRAQNRRLLPDAPNALHILDGPEQRYFLGVVDLATVYGLRKRLEH 158
Query: 364 SWKALVYDGDTVSVHRPSFYADRFLKFMNS 393
WK L Y G T S P+ YA R +++ +
Sbjct: 159 LWKTLRYPGRTFSTVSPARYARRLCQWVEA 188
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 56.2 bits (134), Expect = 7e-08
Identities = 45/164 (27%), Positives = 72/164 (43%), Gaps = 13/164 (7%)
Query: 121 GASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNL----NQNPRTLLPKFYGLY-- 174
G SG+ F+ T DD FI+K + E + P Y+ + Q T L K G+Y
Sbjct: 1860 GKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRI 1919
Query: 175 ----CMQSGGINIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKE-REKSNPTFKDLD 229
+ + ++VM N+ +M +DLKGS R +E + D +
Sbjct: 1920 GYKNSQNNTEKKLDLLVMENLF-YGRKMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDEN 1978
Query: 230 FLQDMHEG-LYFDTETYNALMKTLQRDCRVLESFKIMDYSLLLG 272
L+ + + LY + + L ++ D L S I+DYSLL+G
Sbjct: 1979 LLKMVRDNPLYIRSHSKAVLRTSIHSDSHFLSSHLIIDYSLLVG 2022
>gi|222537754 hypothetical protein LOC375337 [Homo sapiens]
Length = 1692
Score = 32.7 bits (73), Expect = 0.86
Identities = 12/44 (27%), Positives = 28/44 (63%)
Query: 228 LDFLQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLLL 271
+++ + G+YFD + N L+ +L + C + E F+I++ S+++
Sbjct: 1150 MEYYRKFPPGVYFDLQVLNDLLNSLLKHCLLKEVFQIVNLSIMV 1193
>gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 3 [Homo sapiens]
Length = 632
Score = 30.4 bits (67), Expect = 4.3
Identities = 32/143 (22%), Positives = 56/143 (39%), Gaps = 18/143 (12%)
Query: 207 STYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMD 266
S RR + RE+ K + LQ+ HE L + L + V E +
Sbjct: 333 SLLNRRQEERIREQEERLRKQEERLQEQHEKL-----------RQLAKPQSVFEELNNEN 381
Query: 267 YSLLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYSTAMESIQGPGKSGDGIITEN- 325
S L L+ +KE +E+ + +A Q++ ++ ++ G G G+ + +E
Sbjct: 382 KSTLQ----LEQQVKELQEKLGEEHLEAASQQNQQLTAQLSLMALPGEGHGGEHLDSEGE 437
Query: 326 --PDTMGGIPAKSHRGEKLLLFM 346
P M +P E + FM
Sbjct: 438 EAPQPMPSVPEDLESREAMSSFM 460
>gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 3 [Homo sapiens]
Length = 632
Score = 30.0 bits (66), Expect = 5.6
Identities = 32/143 (22%), Positives = 56/143 (39%), Gaps = 18/143 (12%)
Query: 207 STYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMD 266
S RR + RE+ K + LQ+ HE L + L + V E +
Sbjct: 333 SLLNRRQEERIREQEERLRKQEERLQEQHEKL-----------RQLAKPQSVFEELNNEN 381
Query: 267 YSLLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYSTAMESIQGPGKSGDGIITEN- 325
S L L+ +KE +E+ + +A Q++ ++ ++ G G G+ + +E
Sbjct: 382 KSTLQ----LEQQVKELQEKLGEEHLEAASQQNQQLTAQLSLMALPGEGHGGEHLDSEGE 437
Query: 326 --PDTMGGIPAKSHRGEKLLLFM 346
P M +P E + FM
Sbjct: 438 EAPRPMPSVPEDPESREAMSSFM 460
>gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens]
Length = 753
Score = 30.0 bits (66), Expect = 5.6
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 1/47 (2%)
Query: 487 NEHYPHDRPTLYSNSKGL-PSSSTFTLEEGTIYLTAEPNTLEVQDDN 532
+E P D+ + + GL PSSS + T+ + +P TLE +DD+
Sbjct: 18 DELTPDDKMLRFVDKNGLVPSSSGTVYDRTTVLIEQDPGTLEDEDDD 64
>gi|110347463 human immunodeficiency virus type I enhancer binding
protein 2 [Homo sapiens]
Length = 2446
Score = 30.0 bits (66), Expect = 5.6
Identities = 29/118 (24%), Positives = 49/118 (41%), Gaps = 16/118 (13%)
Query: 418 KATSQE-IVSSISQEWKDEKRDLLT-------EGQSFSSLDEEALGSRHRPDLVPSTPSL 469
KATS+ S W+ E+ ++ EGQ ++ E +G+ ++ L
Sbjct: 11 KATSRSGETDKASGRWRQEQSAVIKMSTFGSHEGQRQPQIEPEQIGNT-------ASAQL 63
Query: 470 FEAASLATTISSSSLYVNEHYPHDRPTLYSNSKGLPSSSTFTLEEGTIYLTAEPNTLE 527
F + LA+ + YP RP+ YS L S +L +G ++ T +LE
Sbjct: 64 FGSGKLASPSEVVQQVAEKQYPPHRPSPYSCQHSL-SFPQHSLPQGVMHSTKPHQSLE 120
>gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo
sapiens]
Length = 1085
Score = 29.6 bits (65), Expect = 7.3
Identities = 16/47 (34%), Positives = 26/47 (55%)
Query: 154 GYYMNLNQNPRTLLPKFYGLYCMQSGGINIRIVVMNNVLPRSMRMHF 200
GY+ +LN+ RT L Y L + G++I ++N+ PRS + F
Sbjct: 272 GYHASLNRALRTYLSAEYNLETSRHEGLDIIENAVDNLEPRSDKQRF 318
>gi|34452707 bromodomain containing 8 isoform 2 [Homo sapiens]
Length = 1235
Score = 29.6 bits (65), Expect = 7.3
Identities = 30/99 (30%), Positives = 43/99 (43%), Gaps = 9/99 (9%)
Query: 205 KGSTYKRRASRKER-EKSNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCRVLESFK 263
+ ST K+ AS K+ +P F F+ HE ++ D+E + L DCR L F
Sbjct: 833 RDSTRKQDASEKDSVPMGSPAFLLSLFMG--HEWVWLDSEQDHPNDSELSNDCRSL--FS 888
Query: 264 IMDYSLLLGI----HFLDHSLKEKEEETPQNVPDAKRTG 298
D SL L + D +E EE +P+ P G
Sbjct: 889 SWDSSLDLDVGNWRETEDPEAEELEESSPEREPSELLVG 927
>gi|113425121 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 4 [Homo sapiens]
Length = 632
Score = 29.3 bits (64), Expect = 9.6
Identities = 32/143 (22%), Positives = 55/143 (38%), Gaps = 18/143 (12%)
Query: 207 STYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMD 266
S RR + RE+ K + LQ+ HE L + L + V E +
Sbjct: 333 SLLNRRQEERIREQEERLRKQEERLQEQHEKL-----------RQLAKPQSVFEELNNEN 381
Query: 267 YSLLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYSTAMESIQGPGKSGDGIITEN- 325
S L L+ +KE +E+ + +A Q++ + ++ G G G+ + +E
Sbjct: 382 KSTLQ----LEQQVKELQEKLGEEHLEAASQQNQQLTAQLNLMALPGEGHGGEHLDSEGE 437
Query: 326 --PDTMGGIPAKSHRGEKLLLFM 346
P M +P E + FM
Sbjct: 438 EAPQPMPSVPEDLESREAMSSFM 460
>gi|113425119 PREDICTED: similar to golgi autoantigen, golgin
subfamily a, 8E isoform 2 [Homo sapiens]
Length = 631
Score = 29.3 bits (64), Expect = 9.6
Identities = 31/143 (21%), Positives = 55/143 (38%), Gaps = 18/143 (12%)
Query: 207 STYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMD 266
S RR + RE+ K + LQ+ HE L + L + V E +
Sbjct: 332 SLLNRRQEERIREQEERLRKQEERLQEQHEKL-----------RQLAKPQSVFEELNNEN 380
Query: 267 YSLLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYSTAMESIQGPGKSGDGIITEN- 325
S L L+ +KE +E+ + + Q++ ++ ++ G G G+ + +E
Sbjct: 381 KSTLQ----LEQQVKELQEKLGEEHLEVASQQNQQLTAQLSLMALPGEGHGGEHLDSEGE 436
Query: 326 --PDTMGGIPAKSHRGEKLLLFM 346
P M +P E + FM
Sbjct: 437 EAPQPMPSVPEDPESREAMSSFM 459
>gi|19923233 sterol carrier protein 2 isoform 1 proprotein [Homo
sapiens]
Length = 547
Score = 29.3 bits (64), Expect = 9.6
Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 6/82 (7%)
Query: 170 FYGLYCMQSGGINIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLD 229
F Y +QS + I M LP S + G + A+RK EKS T D+D
Sbjct: 241 FVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDID 300
Query: 230 FLQDMHEGLYFDTE---TYNAL 248
+ ++H+ F T TY AL
Sbjct: 301 VI-ELHD--CFSTNELLTYEAL 319
>gi|55956775 sterol carrier protein 2 isoform 2 [Homo sapiens]
Length = 322
Score = 29.3 bits (64), Expect = 9.6
Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 6/82 (7%)
Query: 170 FYGLYCMQSGGINIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLD 229
F Y +QS + I M LP S + G + A+RK EKS T D+D
Sbjct: 197 FVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDID 256
Query: 230 FLQDMHEGLYFDTE---TYNAL 248
+ ++H+ F T TY AL
Sbjct: 257 VI-ELHD--CFSTNELLTYEAL 275
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,769,280
Number of Sequences: 37866
Number of extensions: 945145
Number of successful extensions: 2486
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2430
Number of HSP's gapped (non-prelim): 31
length of query: 540
length of database: 18,247,518
effective HSP length: 107
effective length of query: 433
effective length of database: 14,195,856
effective search space: 6146805648
effective search space used: 6146805648
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.