Search of human proteins with 4505671

Search of human proteins with 4505671

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505671 phosphodiesterase 6D [Homo sapiens]
         (150 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505671 phosphodiesterase 6D [Homo sapiens]                        304   2e-83
gi|4827048 unc119 (C.elegans) homolog isoform a [Homo sapiens]         44   7e-05
gi|16936535 unc119 (C.elegans) homolog isoform b [Homo sapiens]        42   1e-04
gi|122937500 unc-119 homolog B [Homo sapiens]                          40   7e-04
gi|224809295 xeroderma pigmentosum, complementation group C isof...    30   1.00 
gi|4506467 radixin [Homo sapiens]                                      27   5.0  
gi|40255149 Rho guanine nucleotide exchange factor (GEF) 19 [Hom...    27   5.0  
gi|52426743 cisplatin resistance-associated overexpressed protei...    27   6.5  
gi|19923485 cisplatin resistance-associated overexpressed protei...    27   6.5  
gi|4507401 transcription factor A, mitochondrial [Homo sapiens]        27   8.5  
gi|34101282 sodium channel, nonvoltage-gated 1, delta isoform 2 ...    27   8.5  
gi|194353989 sodium channel, nonvoltage-gated 1, delta isoform 1...    27   8.5  
gi|170784809 kinesin family member 17 isoform b [Homo sapiens]         27   8.5  
gi|170784807 kinesin family member 17 isoform a [Homo sapiens]         27   8.5  

>gi|4505671 phosphodiesterase 6D [Homo sapiens]
          Length = 150

 Score =  304 bits (778), Expect = 2e-83
 Identities = 150/150 (100%), Positives = 150/150 (100%)

Query: 1   MSAKDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVS 60
           MSAKDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVS
Sbjct: 1   MSAKDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVS 60

Query: 61  RELNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPA 120
           RELNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPA
Sbjct: 61  RELNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPA 120

Query: 121 SVLTGNVIIETKFFDDDLLVSTSRVRLFYV 150
           SVLTGNVIIETKFFDDDLLVSTSRVRLFYV
Sbjct: 121 SVLTGNVIIETKFFDDDLLVSTSRVRLFYV 150


>gi|4827048 unc119 (C.elegans) homolog isoform a [Homo sapiens]
          Length = 240

 Score = 43.5 bits (101), Expect = 7e-05
 Identities = 26/99 (26%), Positives = 53/99 (53%), Gaps = 3/99 (3%)

Query: 54  LKCKAVSRELNFSSTEQ-MEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAA 112
           L+ + V   + F+  ++ +  FR+ ++ YF+ Q L+ + F FGF IP+S NT + + +  
Sbjct: 138 LRLRQVGATVEFTVGDKPVNNFRMIERHYFRNQLLKSFDFHFGFCIPSSKNTCEHIYDFP 197

Query: 113 PESQMMPASVLTG--NVIIETKFFDDDLLVSTSRVRLFY 149
           P S+ + + ++        ++ +F DD LV  ++    Y
Sbjct: 198 PLSEELISEMIRHPYETQSDSFYFVDDRLVMHNKADYSY 236


>gi|16936535 unc119 (C.elegans) homolog isoform b [Homo sapiens]
          Length = 220

 Score = 42.4 bits (98), Expect = 1e-04
 Identities = 21/68 (30%), Positives = 40/68 (58%), Gaps = 1/68 (1%)

Query: 54  LKCKAVSRELNFSSTEQ-MEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAA 112
           L+ + V   + F+  ++ +  FR+ ++ YF+ Q L+ + F FGF IP+S NT + + +  
Sbjct: 138 LRLRQVGATVEFTVGDKPVNNFRMIERHYFRNQLLKSFDFHFGFCIPSSKNTCEHIYDFP 197

Query: 113 PESQMMPA 120
           P S+ + A
Sbjct: 198 PLSEELSA 205


>gi|122937500 unc-119 homolog B [Homo sapiens]
          Length = 251

 Score = 40.0 bits (92), Expect = 7e-04
 Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 19/107 (17%)

Query: 22  LRDAETGKILWQ-----------------GTEDLSVPGVEHEARVPKKILKCKAVSRELN 64
           +RD ETG +L++                 G  D+S          P   L+ + V   + 
Sbjct: 101 IRDLETGTVLFEIAKPCVSDQEEDEEEGGGDVDISAGRFVRYQFTPA-FLRLRTVGATVE 159

Query: 65  FSSTEQ-MEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIE 110
           F+  ++ +  FR+ ++ YF+   L+ + F+FGF IP+S NT + + E
Sbjct: 160 FTVGDKPVSNFRMIERHYFREHLLKNFDFDFGFCIPSSRNTCEHIYE 206


>gi|224809295 xeroderma pigmentosum, complementation group C isoform
           1 [Homo sapiens]
          Length = 940

 Score = 29.6 bits (65), Expect = 1.00
 Identities = 21/85 (24%), Positives = 38/85 (44%), Gaps = 7/85 (8%)

Query: 6   ERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVP---GVEHEARVPKKILKCKAVSRE 62
           ++A  + RG  +N  +  + E  +  W+  E+LS P    V       + +L  K V  E
Sbjct: 107 KKAHHLKRGATMNEDSNEEEEESENDWEEVEELSEPVLGDVRESTAFSRSLLPVKPVEIE 166

Query: 63  L----NFSSTEQMEKFRLEQKVYFK 83
           +       + E+ EK +LE + Y +
Sbjct: 167 IETPEQAKTRERSEKIKLEFETYLR 191


>gi|4506467 radixin [Homo sapiens]
          Length = 583

 Score = 27.3 bits (59), Expect = 5.0
 Identities = 25/106 (23%), Positives = 43/106 (40%), Gaps = 6/106 (5%)

Query: 49  VPKKI-LKCKAVSRELNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQS 107
           +PK I ++   +  EL F+        +L  +V       E WFF   +V     +TW  
Sbjct: 1   MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLK 60

Query: 108 LIEAAPESQMMPASVLTGNVIIETKFFDDDL---LVSTSRVRLFYV 150
           L +   +  +   + L        KFF +D+   L+     RLF++
Sbjct: 61  LNKKVTQQDVKKENPL--QFKFRAKFFPEDVSEELIQEITQRLFFL 104


>gi|40255149 Rho guanine nucleotide exchange factor (GEF) 19 [Homo
           sapiens]
          Length = 802

 Score = 27.3 bits (59), Expect = 5.0
 Identities = 28/122 (22%), Positives = 48/122 (39%), Gaps = 21/122 (17%)

Query: 29  KILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSTEQMEK----FRLEQKVYFKG 84
           K+L +     +  G E E    K     K + +E N +S + M++      L +K++F+G
Sbjct: 523 KMLVENILKRTAQGSEDEDMATKAFNALKELVQECN-ASVQSMKRTEELIHLSKKIHFEG 581

Query: 85  QCLE-----EWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLL 139
           +         W    G            L+E AP     PA +   +  +    F+D LL
Sbjct: 582 KIFPLISQARWLVRHG-----------ELVELAPLPAAPPAKLKLSSKAVYLHLFNDCLL 630

Query: 140 VS 141
           +S
Sbjct: 631 LS 632


>gi|52426743 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 26.9 bits (58), Expect = 6.5
 Identities = 16/50 (32%), Positives = 26/50 (52%)

Query: 30  ILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSTEQMEKFRLEQK 79
           +L Q  E+L   G   EA+   K+++     REL  S+T  +E F  ++K
Sbjct: 138 VLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEK 187


>gi|19923485 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 26.9 bits (58), Expect = 6.5
 Identities = 16/50 (32%), Positives = 26/50 (52%)

Query: 30  ILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSTEQMEKFRLEQK 79
           +L Q  E+L   G   EA+   K+++     REL  S+T  +E F  ++K
Sbjct: 138 VLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEK 187


>gi|4507401 transcription factor A, mitochondrial [Homo sapiens]
          Length = 246

 Score = 26.6 bits (57), Expect = 8.5
 Identities = 13/35 (37%), Positives = 18/35 (51%)

Query: 3   AKDERAREILRGFKLNWMNLRDAETGKILWQGTED 37
           AK +  +E L+  K NW NL D+E    +    ED
Sbjct: 173 AKGDSPQEKLKTVKENWKNLSDSEKELYIQHAKED 207


>gi|34101282 sodium channel, nonvoltage-gated 1, delta isoform 2
           [Homo sapiens]
          Length = 638

 Score = 26.6 bits (57), Expect = 8.5
 Identities = 15/55 (27%), Positives = 25/55 (45%), Gaps = 1/55 (1%)

Query: 38  LSVPGVEHEA-RVPKKILKCKAVSRELNFSSTEQMEKFRLEQKVYFKGQCLEEWF 91
           L   G+ H++ R    + K   V +ELN+ S E+   + + Q +   G     WF
Sbjct: 482 LGEQGLPHQSHRQRSSLAKINIVYQELNYRSVEEAPVYSVPQLLSAMGSLCSLWF 536


>gi|194353989 sodium channel, nonvoltage-gated 1, delta isoform 1
           [Homo sapiens]
          Length = 704

 Score = 26.6 bits (57), Expect = 8.5
 Identities = 15/55 (27%), Positives = 25/55 (45%), Gaps = 1/55 (1%)

Query: 38  LSVPGVEHEA-RVPKKILKCKAVSRELNFSSTEQMEKFRLEQKVYFKGQCLEEWF 91
           L   G+ H++ R    + K   V +ELN+ S E+   + + Q +   G     WF
Sbjct: 548 LGEQGLPHQSHRQRSSLAKINIVYQELNYRSVEEAPVYSVPQLLSAMGSLCSLWF 602


>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
          Length = 1028

 Score = 26.6 bits (57), Expect = 8.5
 Identities = 13/26 (50%), Positives = 18/26 (69%)

Query: 1   MSAKDERAREILRGFKLNWMNLRDAE 26
           MSA DER ++ LR  KLN ++L  +E
Sbjct: 220 MSAVDERGKDHLRAGKLNLVDLAGSE 245


>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
          Length = 1029

 Score = 26.6 bits (57), Expect = 8.5
 Identities = 13/26 (50%), Positives = 18/26 (69%)

Query: 1   MSAKDERAREILRGFKLNWMNLRDAE 26
           MSA DER ++ LR  KLN ++L  +E
Sbjct: 220 MSAVDERGKDHLRAGKLNLVDLAGSE 245


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,366,355
Number of Sequences: 37866
Number of extensions: 210614
Number of successful extensions: 458
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 448
Number of HSP's gapped (non-prelim): 15
length of query: 150
length of database: 18,247,518
effective HSP length: 93
effective length of query: 57
effective length of database: 14,725,980
effective search space: 839380860
effective search space used: 839380860
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.