Search of human proteins with 4505351

Search of human proteins with 4505351

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505351 N-deacetylase/N-sulfotransferase (heparan
glucosaminyl) 1 [Homo sapiens]
         (882 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505351 N-deacetylase/N-sulfotransferase (heparan glucosaminy...  1830   0.0  
gi|12007650 heparan sulfate N-deacetylase/N-sulfotransferase 4 [...  1323   0.0  
gi|4758766 N-deacetylase/N-sulfotransferase (heparan glucosaminy...  1318   0.0  
gi|4505353 heparan glucosaminyl N-deacetylase/N-sulfotransferase...  1316   0.0  
gi|5174467 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3...   120   7e-27
gi|5174465 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3...   120   7e-27
gi|104876423 heparan sulfate D-glucosaminyl 3-O-sulfotransferase...   118   3e-26
gi|5174463 heparan sulfate D-glucosaminyl  3-O-sulfotransferase ...   117   6e-26
gi|116089312 heparan sulfate (glucosamine) 3-O-sulfotransferase ...   117   6e-26
gi|45267824 heparan sulfate (glucosamine) 3-O-sulfotransferase 5...   115   1e-25
gi|4826764 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1...   109   1e-23
gi|45505173 B cell RAG associated protein [Homo sapiens]               40   0.007
gi|56847626 sulfotransferase family, cytosolic, 1C, member 3 [Ho...    37   0.11 
gi|62868225 aryl sulfotransferase [Homo sapiens]                       33   0.89 
gi|62868223 aryl sulfotransferase [Homo sapiens]                       33   0.89 
gi|29550921 sulfotransferase family, cytosolic, 1A, phenol-prefe...    33   0.89 
gi|10835035 sulfotransferase family, cytosolic, 1A, phenol-prefe...    33   0.89 
gi|4503591 erythropoietin receptor precursor [Homo sapiens]            32   3.4  
gi|114431248 hypothetical protein LOC205717 [Homo sapiens]             31   4.4  
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    31   4.4  
gi|46909600 a disintegrin and metalloproteinase domain 15 isofor...    31   5.8  
gi|46909598 a disintegrin and metalloproteinase domain 15 isofor...    31   5.8  
gi|46909596 a disintegrin and metalloproteinase domain 15 isofor...    31   5.8  
gi|46909594 a disintegrin and metalloproteinase domain 15 isofor...    31   5.8  
gi|46909590 a disintegrin and metalloproteinase domain 15 isofor...    31   5.8  
gi|4501897 activin A receptor, type IIA precursor [Homo sapiens]       30   7.6  
gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [H...    30   9.9  

>gi|4505351 N-deacetylase/N-sulfotransferase (heparan glucosaminyl)
           1 [Homo sapiens]
          Length = 882

 Score = 1830 bits (4739), Expect = 0.0
 Identities = 882/882 (100%), Positives = 882/882 (100%)

Query: 1   MPALACLRRLCRHVSPQAVLFLLFIFCLFSVFISAYYLYGWKRGLEPSADAPEPDCGDPP 60
           MPALACLRRLCRHVSPQAVLFLLFIFCLFSVFISAYYLYGWKRGLEPSADAPEPDCGDPP
Sbjct: 1   MPALACLRRLCRHVSPQAVLFLLFIFCLFSVFISAYYLYGWKRGLEPSADAPEPDCGDPP 60

Query: 61  PVAPSRLLPLKPVQAATPSRTDPLVLVFVESLYSQLGQEVVAILESSRFKYRTEIAPGKG 120
           PVAPSRLLPLKPVQAATPSRTDPLVLVFVESLYSQLGQEVVAILESSRFKYRTEIAPGKG
Sbjct: 61  PVAPSRLLPLKPVQAATPSRTDPLVLVFVESLYSQLGQEVVAILESSRFKYRTEIAPGKG 120

Query: 121 DMPTLTDKGRGRFALIIYENILKYVNLDAWNRELLDKYCVAYGVGIIGFFKANENSLLSA 180
           DMPTLTDKGRGRFALIIYENILKYVNLDAWNRELLDKYCVAYGVGIIGFFKANENSLLSA
Sbjct: 121 DMPTLTDKGRGRFALIIYENILKYVNLDAWNRELLDKYCVAYGVGIIGFFKANENSLLSA 180

Query: 181 QLKGFPLFLHSNLGLKDCSINPKSPLLYVTRPSEVEKGVLPGEDWTVFQSNHSTYEPVLL 240
           QLKGFPLFLHSNLGLKDCSINPKSPLLYVTRPSEVEKGVLPGEDWTVFQSNHSTYEPVLL
Sbjct: 181 QLKGFPLFLHSNLGLKDCSINPKSPLLYVTRPSEVEKGVLPGEDWTVFQSNHSTYEPVLL 240

Query: 241 AKTRSSESIPHLGADAGLHAALHATVVQDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAF 300
           AKTRSSESIPHLGADAGLHAALHATVVQDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAF
Sbjct: 241 AKTRSSESIPHLGADAGLHAALHATVVQDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAF 300

Query: 301 LTGKRLSLPLDRYILVDIDDIFVGKEGTRMKVEDVKALFDTQNELRAHIPNFTFNLGYSG 360
           LTGKRLSLPLDRYILVDIDDIFVGKEGTRMKVEDVKALFDTQNELRAHIPNFTFNLGYSG
Sbjct: 301 LTGKRLSLPLDRYILVDIDDIFVGKEGTRMKVEDVKALFDTQNELRAHIPNFTFNLGYSG 360

Query: 361 KFFHTGTNAEDAGDDLLLSYVKEFWWFPHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHG 420
           KFFHTGTNAEDAGDDLLLSYVKEFWWFPHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHG
Sbjct: 361 KFFHTGTNAEDAGDDLLLSYVKEFWWFPHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHG 420

Query: 421 IPTDMGYAVAPHHSGVYPVHVQLYEAWKQVWSIRVTSTEEYPHLKPARYRRGFIHNGIMV 480
           IPTDMGYAVAPHHSGVYPVHVQLYEAWKQVWSIRVTSTEEYPHLKPARYRRGFIHNGIMV
Sbjct: 421 IPTDMGYAVAPHHSGVYPVHVQLYEAWKQVWSIRVTSTEEYPHLKPARYRRGFIHNGIMV 480

Query: 481 LPRQTCGLFTHTIFYNEYPGGSSELDKIINGGELFLTVLLNPISIFMTHLSNYGNDRLGL 540
           LPRQTCGLFTHTIFYNEYPGGSSELDKIINGGELFLTVLLNPISIFMTHLSNYGNDRLGL
Sbjct: 481 LPRQTCGLFTHTIFYNEYPGGSSELDKIINGGELFLTVLLNPISIFMTHLSNYGNDRLGL 540

Query: 541 YTFKHLVRFLHSWTNLRLQTLPPVQLAQKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKT 600
           YTFKHLVRFLHSWTNLRLQTLPPVQLAQKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKT
Sbjct: 541 YTFKHLVRFLHSWTNLRLQTLPPVQLAQKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKT 600

Query: 601 CDRFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYME 660
           CDRFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYME
Sbjct: 601 CDRFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYME 660

Query: 661 FFPIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQHQRAH 720
           FFPIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQHQRAH
Sbjct: 661 FFPIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQHQRAH 720

Query: 721 DDPVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKL 780
           DDPVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKL
Sbjct: 721 DDPVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKL 780

Query: 781 LRTEPAKVMDMVQKFLGVTNTIDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEM 840
           LRTEPAKVMDMVQKFLGVTNTIDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEM
Sbjct: 781 LRTEPAKVMDMVQKFLGVTNTIDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEM 840

Query: 841 DLDSRAFLKDYYRDHNIELSKLLYKMGQTLPTWLREDLQNTR 882
           DLDSRAFLKDYYRDHNIELSKLLYKMGQTLPTWLREDLQNTR
Sbjct: 841 DLDSRAFLKDYYRDHNIELSKLLYKMGQTLPTWLREDLQNTR 882


>gi|12007650 heparan sulfate N-deacetylase/N-sulfotransferase 4
           [Homo sapiens]
          Length = 872

 Score = 1323 bits (3425), Expect = 0.0
 Identities = 618/867 (71%), Positives = 731/867 (84%), Gaps = 7/867 (0%)

Query: 17  QAVLFLLFIFCLFSVFISAYYLY-GWKRGLEPSADAPEPDCGDPPPVAPSRLLPLKPVQA 75
           + ++ LL  FCL S+ ISAY+LY G+K+ +       E +C D   + P R + LK V+ 
Sbjct: 12  RTLIVLLATFCLVSIVISAYFLYSGYKQEMTLIETTAEAECTDIK-ILPYRSMELKTVKP 70

Query: 76  ATPSRTDPLVLVFVESLYSQLGQEVVAILESSRFKYRTEIAPGKGDMPTLTDKGRGRFAL 135
              S+TDP VL+FVES YSQLGQ+++AILESSRF+Y   IAPGKGD+P LTD G+G++ L
Sbjct: 71  IDTSKTDPTVLLFVESQYSQLGQDIIAILESSRFQYHMVIAPGKGDIPPLTDNGKGKYTL 130

Query: 136 IIYENILKYVNLDAWNRELLDKYCVAYGVGIIGFFKANENSLLSAQLKGFPLFLHSNLGL 195
           +IYENILKYV++D+WNRELL+KYCV Y V IIGF KANENSL S QLKGFPL L +NL L
Sbjct: 131 VIYENILKYVSMDSWNRELLEKYCVEYSVSIIGFHKANENSLPSTQLKGFPLNLFNNLAL 190

Query: 196 KDCSINPKSPLLYVTRPSEVEKGVLPGEDWTVFQSNHSTYEPVLLAKTRSSESIPHLGAD 255
           KDC +NP+SPLL++T+  +VEKG LPGEDWT+FQ NHSTY+PVLL + ++ +S+  L + 
Sbjct: 191 KDCFVNPQSPLLHITKAPKVEKGPLPGEDWTIFQYNHSTYQPVLLTELQTEKSLSSLSSK 250

Query: 256 AGLHAALHATVVQDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAFLTGKRLSLPLDRYIL 315
                 L ATV+QDLGLHDGIQRVLFGNNLNFWLHKL+F+DA++FL+GKRL+L LDRYIL
Sbjct: 251 T-----LFATVIQDLGLHDGIQRVLFGNNLNFWLHKLIFIDAISFLSGKRLTLSLDRYIL 305

Query: 316 VDIDDIFVGKEGTRMKVEDVKALFDTQNELRAHIPNFTFNLGYSGKFFHTGTNAEDAGDD 375
           VDIDDIFVGKEGTRM V+DVKAL +TQN LR  + NFTFNLG+SGKF+HTGT  ED GDD
Sbjct: 306 VDIDDIFVGKEGTRMNVKDVKALLETQNLLRTQVANFTFNLGFSGKFYHTGTEEEDEGDD 365

Query: 376 LLLSYVKEFWWFPHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHGIPTDMGYAVAPHHSG 435
           LLL  V EFWWFPHMWSHMQPHLFHN+S L EQM LNK+FA+EHGIP +MGYAVAPHHSG
Sbjct: 366 LLLRSVDEFWWFPHMWSHMQPHLFHNESSLVEQMILNKEFALEHGIPINMGYAVAPHHSG 425

Query: 436 VYPVHVQLYEAWKQVWSIRVTSTEEYPHLKPARYRRGFIHNGIMVLPRQTCGLFTHTIFY 495
           VYPVH+QLY AWK+VW I+VTSTEEYPHLKPARYR+GFIHN IMVLPRQTCGLFTHTIFY
Sbjct: 426 VYPVHIQLYAAWKKVWGIQVTSTEEYPHLKPARYRKGFIHNSIMVLPRQTCGLFTHTIFY 485

Query: 496 NEYPGGSSELDKIINGGELFLTVLLNPISIFMTHLSNYGNDRLGLYTFKHLVRFLHSWTN 555
            EYPGG  ELDK I GGELFLT+LLNPISIFMTHLSNYGNDRLGLYTF +LV F+ SWTN
Sbjct: 486 KEYPGGPQELDKSIRGGELFLTILLNPISIFMTHLSNYGNDRLGLYTFVNLVNFVQSWTN 545

Query: 556 LRLQTLPPVQLAQKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKTCDRFPKLLIIGPQKT 615
           L+LQTLPPVQLA +YF++F E+KDPLWQ+PC+DKRHKDIWS+EKTCD  PK L+IGPQKT
Sbjct: 546 LKLQTLPPVQLAHQYFELFPEQKDPLWQNPCDDKRHKDIWSREKTCDHLPKFLVIGPQKT 605

Query: 616 GTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFFPIPSNTTSDFYFE 675
           GTTALYLFL MHP + SN PS +TFEE+QFFNG+NYHKGIDWYM+FFP PSNTTSDF FE
Sbjct: 606 GTTALYLFLLMHPSIISNLPSPKTFEEVQFFNGNNYHKGIDWYMDFFPTPSNTTSDFLFE 665

Query: 676 KSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQHQRAHDDPVALKYTFHEVIT 735
           KSANYF SE APRRAA+L+PKAK++TILI+P+DRAYSWYQHQR+H+DP AL++ F+EVI+
Sbjct: 666 KSANYFHSEEAPRRAASLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAALRFNFYEVIS 725

Query: 736 AGSDASSKLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKLLRTEPAKVMDMVQKF 795
            G  A S L+ LQ RCLVPGWYA HIERWL+ +  +Q+L++DG+ LR++PA VMD VQKF
Sbjct: 726 TGHWAPSDLKTLQRRCLVPGWYAVHIERWLTYFATSQLLIIDGQQLRSDPATVMDEVQKF 785

Query: 796 LGVTNTIDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDLDSRAFLKDYYRDH 855
           LGVT   +Y + L FDP+KGFWCQLLEGGKTKCLGKSKGRKYP MD +SR FL +YYRDH
Sbjct: 786 LGVTPRYNYSEALTFDPQKGFWCQLLEGGKTKCLGKSKGRKYPPMDPESRTFLSNYYRDH 845

Query: 856 NIELSKLLYKMGQTLPTWLREDLQNTR 882
           N+ELSKLL+++GQ LP+WLR++LQ  R
Sbjct: 846 NVELSKLLHRLGQPLPSWLRQELQKVR 872


>gi|4758766 N-deacetylase/N-sulfotransferase (heparan glucosaminyl)
           3 [Homo sapiens]
          Length = 873

 Score = 1318 bits (3411), Expect = 0.0
 Identities = 621/880 (70%), Positives = 730/880 (82%), Gaps = 8/880 (0%)

Query: 4   LACLRRLCRHVSPQAVLFLLFIFCLFSVFISAYYLY-GWKRGLEPSADAPEPDCGDPPPV 62
           ++ + +L RH   Q  + LL  FC+ S+ ISAYYLY G+K+  E S  A E DCGD   +
Sbjct: 1   MSFIMKLHRHF--QRTVILLATFCMVSIIISAYYLYSGYKQENELSETASEVDCGDLQHL 58

Query: 63  APSRLLPLKPVQAATPSRTDPLVLVFVESLYSQLGQEVVAILESSRFKYRTEIAPGKGDM 122
            P +L+ +K ++    SRTDP VLVFVES YS LGQ+++ ILESSRF+Y  EIAPGKGD+
Sbjct: 59  -PYQLMEVKAMKLFDASRTDPTVLVFVESQYSSLGQDIIMILESSRFQYHIEIAPGKGDL 117

Query: 123 PTLTDKGRGRFALIIYENILKYVNLDAWNRELLDKYCVAYGVGIIGFFKANENSLLSAQL 182
           P L DK +G++ LIIYENILKY+N+D+WNR LLDKYCV YGVG+IGF K +E S+ S QL
Sbjct: 118 PVLIDKMKGKYILIIYENILKYINMDSWNRSLLDKYCVEYGVGVIGFHKTSEKSVQSFQL 177

Query: 183 KGFPLFLHSNLGLKDCSINPKSPLLYVTRPSEVEKGVLPGEDWTVFQSNHSTYEPVLLAK 242
           KGFP  ++ NL +KDC INP SPL+ VT+ S++EKG LPG DWTVFQ NHS Y+PV+ AK
Sbjct: 178 KGFPFSIYGNLAVKDCCINPHSPLIRVTKSSKLEKGSLPGTDWTVFQINHSAYQPVIFAK 237

Query: 243 TRSSESIPHLGADAGLHAALHATVVQDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAFLT 302
            ++ E++    + +    A +AT++ DLGLHDGIQRVLFGNNLNFWLHKL+F+DA++FL+
Sbjct: 238 VKTPENL----SPSISKGAFYATIIHDLGLHDGIQRVLFGNNLNFWLHKLIFIDAISFLS 293

Query: 303 GKRLSLPLDRYILVDIDDIFVGKEGTRMKVEDVKALFDTQNELRAHIPNFTFNLGYSGKF 362
           GKRL+L LDRYILVDIDDIFVGKEGTRM   DVKAL DTQN LRA I NFTFNLG+SGKF
Sbjct: 294 GKRLTLSLDRYILVDIDDIFVGKEGTRMNTNDVKALLDTQNLLRAQITNFTFNLGFSGKF 353

Query: 363 FHTGTNAEDAGDDLLLSYVKEFWWFPHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHGIP 422
           +HTGT  ED GDD LL  V EFWWFPHMWSHMQPHLFHN+S L EQM LNKKFA+EHGIP
Sbjct: 354 YHTGTEEEDEGDDCLLGSVDEFWWFPHMWSHMQPHLFHNESSLVEQMILNKKFALEHGIP 413

Query: 423 TDMGYAVAPHHSGVYPVHVQLYEAWKQVWSIRVTSTEEYPHLKPARYRRGFIHNGIMVLP 482
           TDMGYAVAPHHSGVYPVHVQLYEAWK+VW+I++TSTEEYPHLKPARYRRGFIH  IMVLP
Sbjct: 414 TDMGYAVAPHHSGVYPVHVQLYEAWKKVWNIKITSTEEYPHLKPARYRRGFIHKNIMVLP 473

Query: 483 RQTCGLFTHTIFYNEYPGGSSELDKIINGGELFLTVLLNPISIFMTHLSNYGNDRLGLYT 542
           RQTCGLFTHTIFY EYPGG  ELDK I GGELF TV+LNPISIFMTHLSNYGNDRLGLYT
Sbjct: 474 RQTCGLFTHTIFYKEYPGGPKELDKSIQGGELFFTVVLNPISIFMTHLSNYGNDRLGLYT 533

Query: 543 FKHLVRFLHSWTNLRLQTLPPVQLAQKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKTCD 602
           F +L  F+ SWTNLRLQTLPPVQLA KYF++F ++KDPLWQ+PC+DKRH+DIWSKEKTCD
Sbjct: 534 FVNLANFVKSWTNLRLQTLPPVQLAHKYFELFPDQKDPLWQNPCDDKRHRDIWSKEKTCD 593

Query: 603 RFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFF 662
           R PK L+IGPQKTGTTALYLFL MHP + SN PS +TFEE+QFFN +NYH+GIDWYM+FF
Sbjct: 594 RLPKFLVIGPQKTGTTALYLFLVMHPSILSNSPSPKTFEEVQFFNRNNYHRGIDWYMDFF 653

Query: 663 PIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQHQRAHDD 722
           P+PSN T+DF FEKSANYF SE AP+RAA+L+PKAK++TILI+P+DRAYSWYQHQR+H+D
Sbjct: 654 PVPSNVTTDFLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHED 713

Query: 723 PVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKLLR 782
           P ALK++F+EVI+AG  A S+LRALQ RCLVPGWYA+HIERWL  +   Q+L++DG+ LR
Sbjct: 714 PAALKFSFYEVISAGPRAPSELRALQKRCLVPGWYASHIERWLVYFPPFQLLIIDGQQLR 773

Query: 783 TEPAKVMDMVQKFLGVTNTIDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDL 842
           T+PA VMD VQKFLGV    +Y + L FD  KGFWCQLLE GKTKCLGKSKGRKYP MD 
Sbjct: 774 TDPATVMDEVQKFLGVLPHYNYSEALTFDSHKGFWCQLLEEGKTKCLGKSKGRKYPPMDS 833

Query: 843 DSRAFLKDYYRDHNIELSKLLYKMGQTLPTWLREDLQNTR 882
           DSR FL  YYRDHN+ELSKLL+K+GQ LP+WLR++LQ  R
Sbjct: 834 DSRTFLSSYYRDHNVELSKLLHKLGQPLPSWLRQELQKVR 873


>gi|4505353 heparan glucosaminyl N-deacetylase/N-sulfotransferase 2
           [Homo sapiens]
          Length = 883

 Score = 1316 bits (3407), Expect = 0.0
 Identities = 621/879 (70%), Positives = 735/879 (83%), Gaps = 13/879 (1%)

Query: 9   RLCRHVSPQAVLFLLFIFCLFSVFISAYYLYGWKRGLEPSADAPEPDCGD-----PPPVA 63
           R  R +    ++ LL  F L S+   AYY+    +  EP    P  DC       P P  
Sbjct: 9   RPARQLELHRLILLLIAFSLGSMGFLAYYVSTSPKAKEP-LPLPLGDCSSGGAAGPGPAR 67

Query: 64  PSRLLPLKPVQAATPSRTDPLVLVFVESLYSQLGQEVVAILESSRFKYRTEIAPGKGDMP 123
           P   +P +P +    +RT+P+VLVFVES YSQLGQE+VAILESSRF+Y TE+APG+GDMP
Sbjct: 68  PP--VPPRPPRPPETARTEPVVLVFVESAYSQLGQEIVAILESSRFRYSTELAPGRGDMP 125

Query: 124 TLTDKGRGRFALIIYENILKYVNLDAWNRELLDKYCVAYGVGIIGFFKANENSLLSAQLK 183
           TLTD   GR+ L+IYEN+LKYVNLDAW+RELLD+YCV YGVGIIGFF+A+E+SLLSAQLK
Sbjct: 126 TLTDNTHGRYVLVIYENLLKYVNLDAWSRELLDRYCVEYGVGIIGFFRAHEHSLLSAQLK 185

Query: 184 GFPLFLHSNLGLKDCSINPKSPLLYVTRPSEVEKGVLPGEDWTVFQSNHSTYEPVLLAKT 243
           GFPLFLHSNLGL+D  +NP +PLL++TRPS +E G LPG+DWT+FQSNHSTYEPVLLA  
Sbjct: 186 GFPLFLHSNLGLRDYQVNPSAPLLHLTRPSRLEPGPLPGDDWTIFQSNHSTYEPVLLASL 245

Query: 244 RSSE-SIPHLGADAGLHAALHATVVQDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAFLT 302
           R +E ++P       L  A   TVVQDLGLHDGIQRVLFG+ L+FWLHKL+FVDAVA+LT
Sbjct: 246 RPAEPAVP----GPVLRRARLPTVVQDLGLHDGIQRVLFGHGLSFWLHKLIFVDAVAYLT 301

Query: 303 GKRLSLPLDRYILVDIDDIFVGKEGTRMKVEDVKALFDTQNELRAHIPNFTFNLGYSGKF 362
           GKRL L LDRYILVDIDDIFVGKEGTRMKV DV+AL  TQN+LR  +PNFTFNLG+SGKF
Sbjct: 302 GKRLCLDLDRYILVDIDDIFVGKEGTRMKVADVEALLTTQNKLRTLVPNFTFNLGFSGKF 361

Query: 363 FHTGTNAEDAGDDLLLSYVKEFWWFPHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHGIP 422
           +HTGT  EDAGDD+LL + KEFWWFPHMWSHMQPHLFHN+SVLA+QM LNK+FA+EHGIP
Sbjct: 362 YHTGTEEEDAGDDMLLKHRKEFWWFPHMWSHMQPHLFHNRSVLADQMRLNKQFALEHGIP 421

Query: 423 TDMGYAVAPHHSGVYPVHVQLYEAWKQVWSIRVTSTEEYPHLKPARYRRGFIHNGIMVLP 482
           TD+GYAVAPHHSGVYP+H QLYEAWK VW I+VTSTEEYPHL+PARYRRGFIHNGIMVLP
Sbjct: 422 TDLGYAVAPHHSGVYPIHTQLYEAWKSVWGIQVTSTEEYPHLRPARYRRGFIHNGIMVLP 481

Query: 483 RQTCGLFTHTIFYNEYPGGSSELDKIINGGELFLTVLLNPISIFMTHLSNYGNDRLGLYT 542
           RQTCGLFTHTIFYNEYPGGS ELD+ I GGELFLTVLLNPISIFMTHLSNYGNDRLGLYT
Sbjct: 482 RQTCGLFTHTIFYNEYPGGSRELDRSIRGGELFLTVLLNPISIFMTHLSNYGNDRLGLYT 541

Query: 543 FKHLVRFLHSWTNLRLQTLPPVQLAQKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKTCD 602
           F+ LVRFL  WT LRLQTLPPV LAQKYF++F +E+ PLWQ+PC+DKRHKDIWSKEKTCD
Sbjct: 542 FESLVRFLQCWTRLRLQTLPPVPLAQKYFELFPQERSPLWQNPCDDKRHKDIWSKEKTCD 601

Query: 603 RFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFF 662
           R PK LI+GPQKTGTTA++ FL +HP ++S++PS  TFEEIQFFN  NYHKGIDWYM+FF
Sbjct: 602 RLPKFLIVGPQKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHKGIDWYMDFF 661

Query: 663 PIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQHQRAHDD 722
           P+PSN ++DF FEKSA YFDSEV PRR AALLP+AK++T+L NPADRAYSWYQHQRAH D
Sbjct: 662 PVPSNASTDFLFEKSATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSWYQHQRAHGD 721

Query: 723 PVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKLLR 782
           PVAL YTF++VI+A S     LR+LQNRCLVPG+Y+TH++RWL+ Y + Q+L++DG+ LR
Sbjct: 722 PVALNYTFYQVISASSQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIVDGQELR 781

Query: 783 TEPAKVMDMVQKFLGVTNTIDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDL 842
           T PA  M+ +QKFLG+T  ++Y +TL FD  KGFWCQ LEGGKT+CLG+SKGR+YP+MD 
Sbjct: 782 TNPAASMESIQKFLGITPFLNYTRTLRFDDDKGFWCQGLEGGKTRCLGRSKGRRYPDMDT 841

Query: 843 DSRAFLKDYYRDHNIELSKLLYKMGQTLPTWLREDLQNT 881
           +SR FL D++R+HN+ELSKLL ++GQ +P+WLRE+LQ++
Sbjct: 842 ESRLFLTDFFRNHNLELSKLLSRLGQPVPSWLREELQHS 880


>gi|5174467 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1
           [Homo sapiens]
          Length = 390

 Score =  120 bits (300), Expect = 7e-27
 Identities = 83/264 (31%), Positives = 130/264 (49%), Gaps = 21/264 (7%)

Query: 603 RFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFF 662
           + P+ +IIG +K GT AL  FL +HPD+ +         E  FF+  +Y KG+ WY +  
Sbjct: 136 QLPQAIIIGVKKGGTRALLEFLRVHPDVRA------VGAEPHFFD-RSYDKGLAWYRDL- 187

Query: 663 PIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQH--QRAH 720
            +P         EK+ +YF +  AP R +A+    K++ ++ +P  RA S Y     +  
Sbjct: 188 -MPRTLDGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRP 246

Query: 721 DDPVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKL 780
           D P     TF        D S     +       G YA H+E WL  +   Q+L + G+ 
Sbjct: 247 DIPTFESLTFKNRTAGLIDTSWSAIQI-------GIYAKHLEHWLRHFPIRQMLFVSGER 299

Query: 781 LRTEPAKVMDMVQKFLGVTNTIDYHKTLAFDPKKGFWCQLLEGGKTK--CLGKSKGRKYP 838
           L ++PA  +  VQ FLG+   I   K   F+  KGF C     G ++  CLGK+KGR +P
Sbjct: 300 LISDPAGELGRVQDFLGLKRIIT-DKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTHP 358

Query: 839 EMDLDSRAFLKDYYRDHNIELSKL 862
           E+D +    L+++YR  N++  ++
Sbjct: 359 EIDREVVRRLREFYRPFNLKFYQM 382


>gi|5174465 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1
           [Homo sapiens]
          Length = 406

 Score =  120 bits (300), Expect = 7e-27
 Identities = 83/264 (31%), Positives = 130/264 (49%), Gaps = 21/264 (7%)

Query: 603 RFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFF 662
           + P+ +IIG +K GT AL  FL +HPD+ +         E  FF+  +Y KG+ WY +  
Sbjct: 151 QLPQAIIIGVKKGGTRALLEFLRVHPDVRA------VGAEPHFFD-RSYDKGLAWYRDL- 202

Query: 663 PIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQH--QRAH 720
            +P         EK+ +YF +  AP R +A+    K++ ++ +P  RA S Y     +  
Sbjct: 203 -MPRTLDGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRP 261

Query: 721 DDPVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKL 780
           D P     TF        D S     +       G YA H+E WL  +   Q+L + G+ 
Sbjct: 262 DIPTFESLTFKNRTAGLIDTSWSAIQI-------GIYAKHLEHWLRHFPIRQMLFVSGER 314

Query: 781 LRTEPAKVMDMVQKFLGVTNTIDYHKTLAFDPKKGFWCQLLEGGKTK--CLGKSKGRKYP 838
           L ++PA  +  VQ FLG+   I   K   F+  KGF C     G ++  CLGK+KGR +P
Sbjct: 315 LISDPAGELGRVQDFLGLKRIIT-DKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTHP 373

Query: 839 EMDLDSRAFLKDYYRDHNIELSKL 862
           E+D +    L+++YR  N++  ++
Sbjct: 374 EIDREVVRRLREFYRPFNLKFYQM 397


>gi|104876423 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4
           [Homo sapiens]
          Length = 456

 Score =  118 bits (295), Expect = 3e-26
 Identities = 86/277 (31%), Positives = 136/277 (49%), Gaps = 21/277 (7%)

Query: 603 RFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFF 662
           + P+ LIIG +K GT AL   + +HPD+ +         E  FF+  NY KG++WY    
Sbjct: 196 KLPQALIIGVKKGGTRALLEAIRVHPDVRA------VGVEPHFFD-RNYEKGLEWYRNV- 247

Query: 663 PIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQHQRAHDD 722
            +P         EK+ +YF +  AP+R  ++    K++ ++ NP  RA S Y    +   
Sbjct: 248 -MPKTLDGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDYTQTLSKKP 306

Query: 723 PVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKLLR 782
            +    TF EV+   +     + A  +   + G YA H+E WL  +  +QIL + G+ L 
Sbjct: 307 EIP---TF-EVLAFKNRTLGLIDASWSAIRI-GIYALHLENWLQYFPLSQILFVSGERLI 361

Query: 783 TEPAKVMDMVQKFLGVTNTIDYHKTLAFDPKKGFWC--QLLEGGKTKCLGKSKGRKYPEM 840
            +PA  M  VQ FLG+   +   K   F+  KGF C  +  +    +CLGKSKGR +P +
Sbjct: 362 VDPAGEMAKVQDFLGLKRVVT-EKHFYFNKTKGFPCLKKPEDSSAPRCLGKSKGRTHPRI 420

Query: 841 DLDSRAFLKDYYRDHNIELSKLLYKMGQTLPTWLRED 877
           D D    L+ +Y+  N+    + Y+M      W +E+
Sbjct: 421 DPDVIHRLRKFYKPFNL----MFYQMTGQDFQWEQEE 453


>gi|5174463 heparan sulfate D-glucosaminyl  3-O-sulfotransferase 2
           [Homo sapiens]
          Length = 367

 Score =  117 bits (292), Expect = 6e-26
 Identities = 84/260 (32%), Positives = 126/260 (48%), Gaps = 21/260 (8%)

Query: 603 RFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFF 662
           R P+ LI+G +K GT A+  F+ +HPD+ +         E  FF+  NY +G+DWY    
Sbjct: 113 RLPQALIVGVKKGGTRAVLEFIRVHPDVRA------LGTEPHFFD-RNYGRGLDWYRSL- 164

Query: 663 PIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQH--QRAH 720
            +P    S    EK+ +YF ++ APRR   +    K++ ++ NP  RA S Y     +  
Sbjct: 165 -MPRTLESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKP 223

Query: 721 DDPVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKL 780
           D P     +F        D S     +       G Y  H+E WL  +   QI  + G+ 
Sbjct: 224 DIPTFEGLSFRNRTLGLVDVSWNAIRI-------GMYVLHLESWLQYFPLAQIHFVSGER 276

Query: 781 LRTEPAKVMDMVQKFLGVTNTIDYHKTLAFDPKKGFWC--QLLEGGKTKCLGKSKGRKYP 838
           L T+PA  M  VQ FLG+   I   K   F+  KGF C  +       +CLGKSKGR + 
Sbjct: 277 LITDPAGEMGRVQDFLGIKRFIT-DKHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHV 335

Query: 839 EMDLDSRAFLKDYYRDHNIE 858
           ++D +    L+++YR +NI+
Sbjct: 336 QIDPEVIDQLREFYRPYNIK 355


>gi|116089312 heparan sulfate (glucosamine) 3-O-sulfotransferase 6
           [Homo sapiens]
          Length = 311

 Score =  117 bits (292), Expect = 6e-26
 Identities = 80/258 (31%), Positives = 121/258 (46%), Gaps = 22/258 (8%)

Query: 603 RFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFF 662
           RFP+ LI+G +K GT AL  FL +HPD+ +       F+         Y +G+ WY    
Sbjct: 58  RFPQALIVGVKKGGTRALLEFLRLHPDVRALGSEPHFFDRC-------YERGLAWYRSL- 109

Query: 663 PIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQH--QRAH 720
            +P         EK+ +YF +  APRR  A+ P  K++ ++ NP  RA S Y     +  
Sbjct: 110 -MPRTLDGQITMEKTPSYFVTREAPRRIHAMSPDTKLIVVVRNPVTRAISDYAQTLSKTP 168

Query: 721 DDPVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKL 780
             P      F   +     A S +R         G YA H++ WL  +  +  L + G+ 
Sbjct: 169 GLPSFRALAFRHGLGPVDTAWSAVRI--------GLYAQHLDHWLRYFPLSHFLFVSGER 220

Query: 781 LRTEPAKVMDMVQKFLGVTNTIDYHKTLAFDPKKGFWC--QLLEGGKTKCLGKSKGRKYP 838
           L ++PA  +  VQ FLG+   +   K   F+  KGF C  +   G + +CLGKSKGR +P
Sbjct: 221 LVSDPAGEVGRVQDFLGLKRVVT-DKHFYFNATKGFPCLKKAQGGSRPRCLGKSKGRPHP 279

Query: 839 EMDLDSRAFLKDYYRDHN 856
            +       L+++YR  N
Sbjct: 280 RVPQALVRRLQEFYRPFN 297


>gi|45267824 heparan sulfate (glucosamine) 3-O-sulfotransferase 5
           [Homo sapiens]
          Length = 346

 Score =  115 bits (289), Expect = 1e-25
 Identities = 87/272 (31%), Positives = 129/272 (47%), Gaps = 21/272 (7%)

Query: 603 RFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFF-NGHNYHKGIDWYMEF 661
           + PK +IIG +K GT AL   L +HP +       +  +EI FF N  NY KGI+WY + 
Sbjct: 89  QLPKAIIIGVRKGGTRALLEMLNLHPAVV------KASQEIHFFDNDENYGKGIEWYRK- 141

Query: 662 FPIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWY-QHQRAH 720
             +P +       EKS  YF +E  P R   +    K+L I+  P  RA S Y Q     
Sbjct: 142 -KMPFSYPQQITIEKSPAYFITEEVPERIYKMNSSIKLLIIVREPTTRAISDYTQVLEGK 200

Query: 721 DDPVALKYTFHEVITAGS--DASSKLRALQNRCLVPGWYATHIERWLSAYHANQILVLDG 778
           +      Y F ++    +  + ++K +A++        Y  H+ERWL  +   Q  V+DG
Sbjct: 201 ERKNKTYYKFEKLAIDPNTCEVNTKYKAVRTSI-----YTKHLERWLKYFPIEQFHVVDG 255

Query: 779 KLLRTEPAKVMDMVQKFLGVTNTIDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYP 838
             L TEP   + +V+KFL +   I  +  L F+  +GF+C        KCL  SKGR +P
Sbjct: 256 DRLITEPLPELQLVEKFLNLPPRISQY-NLYFNATRGFYCLRFNIIFNKCLAGSKGRIHP 314

Query: 839 EMDLDSRAFLKDYYRDHNIELSKLLYKMGQTL 870
           E+D      L+ ++   N    K     G+TL
Sbjct: 315 EVDPSVITKLRKFFHPFN---QKFYQITGRTL 343


>gi|4826764 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1
           precursor [Homo sapiens]
          Length = 307

 Score =  109 bits (272), Expect = 1e-23
 Identities = 76/270 (28%), Positives = 135/270 (50%), Gaps = 25/270 (9%)

Query: 600 TCDRFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGH-NYHKGIDWY 658
           +  + P+ +IIG +K GT AL   L +HPD+++         E+ FF+   +Y  G+ WY
Sbjct: 50  SAQQLPQTIIIGVRKGGTRALLEMLSLHPDVAA------AENEVHFFDWEEHYSHGLGWY 103

Query: 659 MEFFPIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYS-----W 713
           +    +P +       EK+  YF S   P R  ++ P  ++L IL +P++R  S     +
Sbjct: 104 LS--QMPFSWPHQLTVEKTPAYFTSPKVPERVYSMNPSIRLLLILRDPSERVLSDYTQVF 161

Query: 714 YQHQRAHDDPVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHANQI 773
           Y H + H    +++    E +      +   +AL NR L    Y  H++ WL  +    I
Sbjct: 162 YNHMQKHKPYPSIE----EFLVRDGRLNVDYKAL-NRSL----YHVHMQNWLRFFPLRHI 212

Query: 774 LVLDGKLLRTEPAKVMDMVQKFLGVTNTIDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSK 833
            ++DG  L  +P   +  V++FL ++  I+      F+  KGF+C L + G+ +CL +SK
Sbjct: 213 HIVDGDRLIRDPFPEIQKVERFLKLSPQINA-SNFYFNKTKGFYC-LRDSGRDRCLHESK 270

Query: 834 GRKYPEMDLDSRAFLKDYYRDHNIELSKLL 863
           GR +P++D      L +Y+ + N +  +L+
Sbjct: 271 GRAHPQVDPKLLNKLHEYFHEPNKKFFELV 300


>gi|45505173 B cell RAG associated protein [Homo sapiens]
          Length = 561

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 64/317 (20%), Positives = 115/317 (36%), Gaps = 77/317 (24%)

Query: 605 PKLLIIGPQKTGTTALYLFLGMHPDLS------SNYPSSETFEEIQFFNGHNYHKGIDWY 658
           P   IIG  K GTT LY  L +HP++        ++ + + F  ++  +G      ++ Y
Sbjct: 254 PHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRLRDGLRDRYPVEDY 313

Query: 659 MEFFPIPS---------------------------------NTTSDFYFEKSANYFDSEV 685
           ++ F + +                                 N    F+++ S +     +
Sbjct: 314 LDLFDLAAHQIHQGLQASSAKEQSKMNTIIIGEASASTMWDNNAWTFFYDNSTDGEPPFL 373

Query: 686 APRRAAALLPKAKVLTILINPADRAYSWYQH----QRAHDDPVALKYTFHEVITAGSDAS 741
                 A  P A+++ +L +P +R YS Y +     ++ DD       FHE +T      
Sbjct: 374 TQDFIHAFQPNARLIVMLRDPVERLYSDYLYFASSNKSADD-------FHEKVTEALQLF 426

Query: 742 SK------LRA------LQNRC---LVPGWYATHIERWLSAYHANQILVLDGKLLRTEPA 786
                   LRA      L N     L  G YA ++  WLS +   Q L+L  +   +   
Sbjct: 427 ENCMLDYSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRLEDHASNVK 486

Query: 787 KVMDMVQKFLGVTNTIDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDLDSRA 846
             M  V +FL +    +  +             L+         + + R    M   ++ 
Sbjct: 487 YTMHKVFQFLNLGPLSEKQEA------------LMTKSPASNARRPEDRNLGPMWPITQK 534

Query: 847 FLKDYYRDHNIELSKLL 863
            L+D+YR  N  L+++L
Sbjct: 535 ILRDFYRPFNARLAQVL 551


>gi|56847626 sulfotransferase family, cytosolic, 1C, member 3 [Homo
           sapiens]
          Length = 304

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 57/240 (23%), Positives = 95/240 (39%), Gaps = 47/240 (19%)

Query: 592 KDIWSKEKTCDRFPKLLIIGPQ-KTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHN 650
           K+ W K       P  LI+    K+GTT ++  L    D+  N    E  +  Q  + H 
Sbjct: 33  KEWWEKVCNFQAKPDDLILATYPKSGTTWMHEIL----DMILNDGDVEKCKRAQTLDRHA 88

Query: 651 YHKGIDWYMEF-FPIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKA------KVLTIL 703
           +       +E  FP       +F  E S+        P     L+P +      K++ + 
Sbjct: 89  F-------LELKFPHKEKPDLEFVLEMSSPQLIKTHLPSH---LIPPSIWKENCKIVYVA 138

Query: 704 INPADRAYSWYQHQRAHD---DPVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATH 760
            NP D   S+Y   R      DP  L+  F+E   +G              +V G +  H
Sbjct: 139 RNPKDCLVSYYHFHRMASFMPDPQNLE-EFYEKFMSGK-------------VVGGSWFDH 184

Query: 761 IERWLSAYHANQILVLDGKLLRTEPAKVMDMVQKFL------GVTNTIDYHKTLAFDPKK 814
           ++ W +A   ++IL L  + ++ +P + ++ + KFL       + N I YH   +FD  K
Sbjct: 185 VKGWWAAKDMHRILYLFYEDIKKDPKREIEKILKFLEKDISEEILNKIIYH--TSFDVMK 242


>gi|62868225 aryl sulfotransferase [Homo sapiens]
          Length = 295

 Score = 33.5 bits (75), Expect = 0.89
 Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 23/115 (20%)

Query: 692 ALLP------KAKVLTILINPADRAYSWYQHQR---AHDDPVALKYTFHEVITAGSDASS 742
           ALLP      K KV+ +  NP D A S+Y   R   AH +P     +F E   AG  +  
Sbjct: 112 ALLPQTLLDQKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWD-SFLEKFMAGEVSYG 170

Query: 743 KLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKLLRTEPAKVMDMVQKFLG 797
                        WY  H++ W      + +L L  + ++  P + +  + +F+G
Sbjct: 171 ------------SWY-QHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVG 212


>gi|62868223 aryl sulfotransferase [Homo sapiens]
          Length = 295

 Score = 33.5 bits (75), Expect = 0.89
 Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 23/115 (20%)

Query: 692 ALLP------KAKVLTILINPADRAYSWYQHQR---AHDDPVALKYTFHEVITAGSDASS 742
           ALLP      K KV+ +  NP D A S+Y   R   AH +P     +F E   AG  +  
Sbjct: 112 ALLPQTLLDQKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWD-SFLEKFMAGEVSYG 170

Query: 743 KLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKLLRTEPAKVMDMVQKFLG 797
                        WY  H++ W      + +L L  + ++  P + +  + +F+G
Sbjct: 171 ------------SWY-QHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVG 212


>gi|29550921 sulfotransferase family, cytosolic, 1A,
           phenol-preferring, member 3 [Homo sapiens]
          Length = 295

 Score = 33.5 bits (75), Expect = 0.89
 Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 23/115 (20%)

Query: 692 ALLP------KAKVLTILINPADRAYSWYQHQR---AHDDPVALKYTFHEVITAGSDASS 742
           ALLP      K KV+ +  NP D A S+Y   R   AH +P     +F E   AG  +  
Sbjct: 112 ALLPQTLLDQKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWD-SFLEKFMAGEVSYG 170

Query: 743 KLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKLLRTEPAKVMDMVQKFLG 797
                        WY  H++ W      + +L L  + ++  P + +  + +F+G
Sbjct: 171 ------------SWY-QHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVG 212


>gi|10835035 sulfotransferase family, cytosolic, 1A,
           phenol-preferring, member 3 [Homo sapiens]
          Length = 295

 Score = 33.5 bits (75), Expect = 0.89
 Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 23/115 (20%)

Query: 692 ALLP------KAKVLTILINPADRAYSWYQHQR---AHDDPVALKYTFHEVITAGSDASS 742
           ALLP      K KV+ +  NP D A S+Y   R   AH +P     +F E   AG  +  
Sbjct: 112 ALLPQTLLDQKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWD-SFLEKFMAGEVSYG 170

Query: 743 KLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKLLRTEPAKVMDMVQKFLG 797
                        WY  H++ W      + +L L  + ++  P + +  + +F+G
Sbjct: 171 ------------SWY-QHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVG 212


>gi|4503591 erythropoietin receptor precursor [Homo sapiens]
          Length = 508

 Score = 31.6 bits (70), Expect = 3.4
 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 4/74 (5%)

Query: 71  KPVQAATPSRTDPLVLVFVESLYSQLGQEVVAILESSRFKYRTEIAPG----KGDMPTLT 126
           +PV   TPS  DPL+L     L   L    V  L S R   + +I PG    + +   L 
Sbjct: 238 EPVSLLTPSDLDPLILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLF 297

Query: 127 DKGRGRFALIIYEN 140
              +G F L +Y+N
Sbjct: 298 TTHKGNFQLWLYQN 311


>gi|114431248 hypothetical protein LOC205717 [Homo sapiens]
          Length = 2245

 Score = 31.2 bits (69), Expect = 4.4
 Identities = 21/74 (28%), Positives = 32/74 (43%), Gaps = 13/74 (17%)

Query: 388  PHMWS--HMQPHLFHNQSVLAEQMALNKKFAVEHGIPTDMGYAVAPHHSGV--------- 436
            PH  S  H QPH  H Q  L +++ + KK  +  G  T    ++ P H G          
Sbjct: 1496 PHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQTSQ-LSLQPKHHGTDQSRSKTGQ 1554

Query: 437  -YPVHVQLYEAWKQ 449
             +P H Q+ +  +Q
Sbjct: 1555 PHPHHQQMQQQMQQ 1568


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 31.2 bits (69), Expect = 4.4
 Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 2/40 (5%)

Query: 47   PSADAPEPDCGDPPPVAPSRLLPL--KPVQAATPSRTDPL 84
            P +  PE +C DP PV P  L P    PV  A+P   +PL
Sbjct: 981  PISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPL 1020


>gi|46909600 a disintegrin and metalloproteinase domain 15 isoform 6
           preproprotein [Homo sapiens]
          Length = 863

 Score = 30.8 bits (68), Expect = 5.8
 Identities = 15/30 (50%), Positives = 16/30 (53%)

Query: 43  RGLEPSADAPEPDCGDPPPVAPSRLLPLKP 72
           +G  PS D P P  G PP V PSR  P  P
Sbjct: 827 QGRCPSGDLPGPGAGIPPLVVPSRPAPPPP 856


>gi|46909598 a disintegrin and metalloproteinase domain 15 isoform 5
           preproprotein [Homo sapiens]
          Length = 862

 Score = 30.8 bits (68), Expect = 5.8
 Identities = 15/30 (50%), Positives = 16/30 (53%)

Query: 43  RGLEPSADAPEPDCGDPPPVAPSRLLPLKP 72
           +G  PS D P P  G PP V PSR  P  P
Sbjct: 826 QGRCPSGDLPGPGAGIPPLVVPSRPAPPPP 855


>gi|46909596 a disintegrin and metalloproteinase domain 15 isoform 4
           preproprotein [Homo sapiens]
          Length = 838

 Score = 30.8 bits (68), Expect = 5.8
 Identities = 15/30 (50%), Positives = 16/30 (53%)

Query: 43  RGLEPSADAPEPDCGDPPPVAPSRLLPLKP 72
           +G  PS D P P  G PP V PSR  P  P
Sbjct: 802 QGRCPSGDLPGPGAGIPPLVVPSRPAPPPP 831


>gi|46909594 a disintegrin and metalloproteinase domain 15 isoform 3
           preproprotein [Homo sapiens]
          Length = 839

 Score = 30.8 bits (68), Expect = 5.8
 Identities = 15/30 (50%), Positives = 16/30 (53%)

Query: 43  RGLEPSADAPEPDCGDPPPVAPSRLLPLKP 72
           +G  PS D P P  G PP V PSR  P  P
Sbjct: 803 QGRCPSGDLPGPGAGIPPLVVPSRPAPPPP 832


>gi|46909590 a disintegrin and metalloproteinase domain 15 isoform 2
           preproprotein [Homo sapiens]
          Length = 814

 Score = 30.8 bits (68), Expect = 5.8
 Identities = 15/30 (50%), Positives = 16/30 (53%)

Query: 43  RGLEPSADAPEPDCGDPPPVAPSRLLPLKP 72
           +G  PS D P P  G PP V PSR  P  P
Sbjct: 778 QGRCPSGDLPGPGAGIPPLVVPSRPAPPPP 807


>gi|4501897 activin A receptor, type IIA precursor [Homo sapiens]
          Length = 513

 Score = 30.4 bits (67), Expect = 7.6
 Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 3/53 (5%)

Query: 22  LLFIFCLFSVFISAYYLYGWKRGLEPSADAPEPDCGDPPPVAPSRLLPLKPVQ 74
           L+ +  +  + I A+++Y   +   P    P  D G PP   PS LL LKP+Q
Sbjct: 144 LVPLMLIAGIVICAFWVYRHHKMAYPPVLVPTQDPGPPP---PSPLLGLKPLQ 193


>gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [Homo
           sapiens]
          Length = 1447

 Score = 30.0 bits (66), Expect = 9.9
 Identities = 33/147 (22%), Positives = 62/147 (42%), Gaps = 6/147 (4%)

Query: 228 FQSNHSTYEPVLLAKTRSSESIPHLGADAGLHAALHATVVQDLGLHDGIQRVLFGNNLNF 287
           F    S   PVL  K++         A   +HA   +   Q   + + + + L  +NL  
Sbjct: 703 FPHIRSALLPVLHHKSKKGPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEH 762

Query: 288 WLHKLVFVDAVAFLTGKRLSLPLD----RYILVDI--DDIFVGKEGTRMKVEDVKALFDT 341
            +  LV +  +A L   + + PL      +I+ D+  +D   GK+ T++ V D +   +T
Sbjct: 763 LITPLVTIGHIALLAPDQFAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPET 822

Query: 342 QNELRAHIPNFTFNLGYSGKFFHTGTN 368
             +++A      + LG       +GT+
Sbjct: 823 MVKIQAIKMMVRWLLGMKNNHSKSGTS 849


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.139    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,402,188
Number of Sequences: 37866
Number of extensions: 1667126
Number of successful extensions: 4388
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 4320
Number of HSP's gapped (non-prelim): 41
length of query: 882
length of database: 18,247,518
effective HSP length: 111
effective length of query: 771
effective length of database: 14,044,392
effective search space: 10828226232
effective search space used: 10828226232
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.