Guide to the Human Genome
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Search of human proteins with 130499472

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|130499472 PIH1 domain containing 2 isoform 2 [Homo sapiens]
         (288 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|130499472 PIH1 domain containing 2 isoform 2 [Homo sapiens]        574   e-164
gi|20270333 PIH1 domain containing 2 isoform 1 [Homo sapiens]         541   e-154
gi|8923598 NOP17 [Homo sapiens]                                        47   2e-05
gi|4759082 serum deprivation response protein [Homo sapiens]           33   0.38 
gi|38261962 activating transcription factor 7 interacting protei...    30   2.5  
gi|4758416 golgi-specific brefeldin A resistant guanine nucleoti...    30   2.5  
gi|40538794 coiled-coil domain containing 21 [Homo sapiens]            30   3.2  
gi|4502175 apical protein of Xenopus-like [Homo sapiens]               29   4.2  
gi|156119615 myosin IXA [Homo sapiens]                                 28   9.3  
gi|55770834 centromere protein F [Homo sapiens]                        28   9.3  

>gi|130499472 PIH1 domain containing 2 isoform 2 [Homo sapiens]
          Length = 288

 Score =  574 bits (1479), Expect = e-164
 Identities = 288/288 (100%), Positives = 288/288 (100%)

Query: 1   METSSKGLLTQVTQFWNLLDDLAQSDPEGYEKFIQQQLKEGKQLCAAPEPQLCLQTRILK 60
           METSSKGLLTQVTQFWNLLDDLAQSDPEGYEKFIQQQLKEGKQLCAAPEPQLCLQTRILK
Sbjct: 1   METSSKGLLTQVTQFWNLLDDLAQSDPEGYEKFIQQQLKEGKQLCAAPEPQLCLQTRILK 60

Query: 61  PKEKILFINLCQWTRIPAPQSTTHPVPLTVGKPEDTTEISDAYTVIDVAYNPDVLHAAEK 120
           PKEKILFINLCQWTRIPAPQSTTHPVPLTVGKPEDTTEISDAYTVIDVAYNPDVLHAAEK
Sbjct: 61  PKEKILFINLCQWTRIPAPQSTTHPVPLTVGKPEDTTEISDAYTVIDVAYNPDVLHAAEK 120

Query: 121 DQVKKNQLIQMAMKCIEEKFQFTLSHSYHITKFRIKGSIQRMKQNLMGIQTDSIDLREKM 180
           DQVKKNQLIQMAMKCIEEKFQFTLSHSYHITKFRIKGSIQRMKQNLMGIQTDSIDLREKM
Sbjct: 121 DQVKKNQLIQMAMKCIEEKFQFTLSHSYHITKFRIKGSIQRMKQNLMGIQTDSIDLREKM 180

Query: 181 RRELTLGQIRSSTMSNPDHFPQLLLPKDQVSGKAVCLIEEISSTEIQVEMKMPAYELKIV 240
           RRELTLGQIRSSTMSNPDHFPQLLLPKDQVSGKAVCLIEEISSTEIQVEMKMPAYELKIV
Sbjct: 181 RRELTLGQIRSSTMSNPDHFPQLLLPKDQVSGKAVCLIEEISSTEIQVEMKMPAYELKIV 240

Query: 241 HDHSEKPLKIELKVELPGINSVSLCDLSVSEGTTEPQALAKDELSLKF 288
           HDHSEKPLKIELKVELPGINSVSLCDLSVSEGTTEPQALAKDELSLKF
Sbjct: 241 HDHSEKPLKIELKVELPGINSVSLCDLSVSEGTTEPQALAKDELSLKF 288


>gi|20270333 PIH1 domain containing 2 isoform 1 [Homo sapiens]
          Length = 315

 Score =  541 bits (1395), Expect = e-154
 Identities = 271/271 (100%), Positives = 271/271 (100%)

Query: 1   METSSKGLLTQVTQFWNLLDDLAQSDPEGYEKFIQQQLKEGKQLCAAPEPQLCLQTRILK 60
           METSSKGLLTQVTQFWNLLDDLAQSDPEGYEKFIQQQLKEGKQLCAAPEPQLCLQTRILK
Sbjct: 1   METSSKGLLTQVTQFWNLLDDLAQSDPEGYEKFIQQQLKEGKQLCAAPEPQLCLQTRILK 60

Query: 61  PKEKILFINLCQWTRIPAPQSTTHPVPLTVGKPEDTTEISDAYTVIDVAYNPDVLHAAEK 120
           PKEKILFINLCQWTRIPAPQSTTHPVPLTVGKPEDTTEISDAYTVIDVAYNPDVLHAAEK
Sbjct: 61  PKEKILFINLCQWTRIPAPQSTTHPVPLTVGKPEDTTEISDAYTVIDVAYNPDVLHAAEK 120

Query: 121 DQVKKNQLIQMAMKCIEEKFQFTLSHSYHITKFRIKGSIQRMKQNLMGIQTDSIDLREKM 180
           DQVKKNQLIQMAMKCIEEKFQFTLSHSYHITKFRIKGSIQRMKQNLMGIQTDSIDLREKM
Sbjct: 121 DQVKKNQLIQMAMKCIEEKFQFTLSHSYHITKFRIKGSIQRMKQNLMGIQTDSIDLREKM 180

Query: 181 RRELTLGQIRSSTMSNPDHFPQLLLPKDQVSGKAVCLIEEISSTEIQVEMKMPAYELKIV 240
           RRELTLGQIRSSTMSNPDHFPQLLLPKDQVSGKAVCLIEEISSTEIQVEMKMPAYELKIV
Sbjct: 181 RRELTLGQIRSSTMSNPDHFPQLLLPKDQVSGKAVCLIEEISSTEIQVEMKMPAYELKIV 240

Query: 241 HDHSEKPLKIELKVELPGINSVSLCDLSVSE 271
           HDHSEKPLKIELKVELPGINSVSLCDLSVSE
Sbjct: 241 HDHSEKPLKIELKVELPGINSVSLCDLSVSE 271


>gi|8923598 NOP17 [Homo sapiens]
          Length = 290

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 29/174 (16%)

Query: 25  SDPEGYEKFIQQQLKEGKQLCAA--------PEPQLCLQTRILKPKEKILFINLCQWTRI 76
           +D   +E+ + Q  KE +Q            P+P  C++T   + K   +FIN+C    I
Sbjct: 19  ADSARFEELLLQASKELQQAQTTRPESTQIQPQPGFCIKTNSSEGK---VFINICHSPSI 75

Query: 77  PAPQSTTHP--------------VPLTVGKPEDTTEIS-DAYTVIDVAYNPDVLHAAEKD 121
           P P   T                +P+++G+P    +      T  DVA N D     +  
Sbjct: 76  PPPADVTEEELLQMLEEDQAGFRIPMSLGEPHAELDAKGQGCTAYDVAVNSDFYRRMQNS 135

Query: 122 QVKKNQLIQMAMKCIEEKFQFTLSHSYHITKFR-IKGSIQRMKQNLMGIQTDSI 174
              +  +I +A + +E+K+   L+  + + K R   GSI   +QN+   Q   I
Sbjct: 136 DFLRELVITIAREGLEDKYNLQLNPEWRMMKNRPFMGSIS--QQNIRSEQRPRI 187


>gi|4759082 serum deprivation response protein [Homo sapiens]
          Length = 425

 Score = 32.7 bits (73), Expect = 0.38
 Identities = 58/266 (21%), Positives = 105/266 (39%), Gaps = 27/266 (10%)

Query: 1   METSSKGLLTQVTQFWNLLDDLAQSDPEGYEKFIQQQLKEGKQLCAAPE--PQLCLQTRI 58
           +E S KG+   +T+    L     S      K +++  K      A  E   + C Q + 
Sbjct: 86  LEGSVKGIQNDLTK----LSKYQASTSNTVSKLLEKSRKVSAHTRAVKERMDRQCAQVKR 141

Query: 59  LKPKE---------KILFINLCQWTRIPAPQSTTHPVPLTV-GK---PEDTTEISDAYTV 105
           L+            K+L     +   IPA      PV   V GK   P++   + +    
Sbjct: 142 LENNHAQLLRRNHFKVLIFQ--EENEIPASVFVKQPVSGAVEGKEELPDENKSLEETLHT 199

Query: 106 IDVAYNPDVLHAAEKDQVKKNQLIQMAMKCIEEKFQFTLSHSYHITKFRIKGSIQRMKQN 165
           +D++ + D+ H  E  +    + ++ +    E+  + +L     + K   + +I++ K N
Sbjct: 200 VDLSSDDDLPHDEEALEDSAEEKVEESRA--EKIKRSSLKKVDSLKKAFSRQNIEK-KMN 256

Query: 166 LMGIQTDSIDLREKMRRELTLG-QIRSSTMSNPDHFPQLLLPKDQVSGKAVCLIEEISST 224
            +G +  S++ REK+++ LT   Q  SS  S+P     L   + +V         E  S 
Sbjct: 257 KLGTKIVSVERREKIKKSLTSNHQKISSGKSSPFKVSPLTFGRKKVREGESHAENETKSE 316

Query: 225 EIQVEMKMP--AYELKIVHDHSEKPL 248
           ++    +MP    E      HSE  L
Sbjct: 317 DLPSSEQMPNDQEEESFAEGHSEASL 342


>gi|38261962 activating transcription factor 7 interacting protein
           [Homo sapiens]
          Length = 1270

 Score = 30.0 bits (66), Expect = 2.5
 Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 7/92 (7%)

Query: 163 KQNLMGIQTDSIDLREKMRRELTLGQIRSSTMSNPDHFPQLLLPKDQVSG-----KAVCL 217
           K +L+ I   + DL EKM         + S+ S P     +L  ++ +SG     + +  
Sbjct: 454 KTSLLPIDETNPDLEEKMESSFGSPSKQESSESLPKEAFLVLSDEEDISGEKDESEVISQ 513

Query: 218 IEEISSTEIQVEMK--MPAYELKIVHDHSEKP 247
            E  S  E++   K   P  E +++H+  E+P
Sbjct: 514 NETCSPAEVESNEKDNKPEEEEQVIHEDDERP 545


>gi|4758416 golgi-specific brefeldin A resistant guanine nucleotide
           exchange factor 1 [Homo sapiens]
          Length = 1859

 Score = 30.0 bits (66), Expect = 2.5
 Identities = 20/79 (25%), Positives = 38/79 (48%), Gaps = 2/79 (2%)

Query: 69  NLCQWTRIPAPQSTT-HPVPLTVGKPEDTTEISDAYTVIDVAY-NPDVLHAAEKDQVKKN 126
           +L + T +   QS +   +P  + +     + SD+ +V D+ Y NP  +   +  Q +  
Sbjct: 335 DLQEGTHVEKSQSASVESIPEVLEECTSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGT 394

Query: 127 QLIQMAMKCIEEKFQFTLS 145
            L+   + CI E F+F +S
Sbjct: 395 ALVPYGLPCIRELFRFLIS 413


>gi|40538794 coiled-coil domain containing 21 [Homo sapiens]
          Length = 762

 Score = 29.6 bits (65), Expect = 3.2
 Identities = 32/122 (26%), Positives = 50/122 (40%), Gaps = 13/122 (10%)

Query: 109 AYNPDVLHAAEKDQVKKNQLIQMAMKCIEEKFQFTLS-HSYHITKF--RIKGSIQRMKQN 165
           A   + L   + D  KK    ++ ++ I E  +  L  HS  + K   R+KG  + +   
Sbjct: 399 AQKTEALSREKIDLEKKLSASEVEVQLIRESLKVALQKHSEEVKKQEERVKGRDKHINNL 458

Query: 166 LMGIQTDSIDLREKMRRELTLGQIRSSTMSNPDHFPQLLLPKDQVSGKAVCLIEEISSTE 225
               Q +S   REK +R  TL +  +   +  DH  Q    KD           E+ STE
Sbjct: 459 KKKCQKESEQNREKQQRIETLERYLADLPTLEDHQKQSQQLKD----------SELKSTE 508

Query: 226 IQ 227
           +Q
Sbjct: 509 LQ 510


>gi|4502175 apical protein of Xenopus-like [Homo sapiens]
          Length = 1616

 Score = 29.3 bits (64), Expect = 4.2
 Identities = 21/78 (26%), Positives = 32/78 (41%)

Query: 47   APEPQLCLQTRILKPKEKILFINLCQWTRIPAPQSTTHPVPLTVGKPEDTTEISDAYTVI 106
            +P PQ   Q    KP   I   +  +  R+    +T   VP+ +   E   E     ++ 
Sbjct: 1171 SPSPQFAPQKLTDKPPLLIQDEDSTRIERVMDNNTTVKMVPIKIVHSESQPEKESRQSLA 1230

Query: 107  DVAYNPDVLHAAEKDQVK 124
              A  P + H  EKDQ+K
Sbjct: 1231 CPAEPPALPHGLEKDQIK 1248


>gi|156119615 myosin IXA [Homo sapiens]
          Length = 2548

 Score = 28.1 bits (61), Expect = 9.3
 Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 7/66 (10%)

Query: 103 YTVIDVAYNPDVLHAAEKDQVKKNQLIQMAMKCIEEKFQFTLSHSYHITKFRIKGSIQRM 162
           Y V DVAY+  +       Q KKNQ I ++ +    K Q T    +H+T    KG    +
Sbjct: 216 YAVADVAYHAML-------QRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKGFASGV 268

Query: 163 KQNLMG 168
           +Q ++G
Sbjct: 269 EQIILG 274


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 28.1 bits (61), Expect = 9.3
 Identities = 41/183 (22%), Positives = 74/183 (40%), Gaps = 32/183 (17%)

Query: 115  LHAAEKDQVKKNQLI-------QMAMKCIEEKFQFTLSHSYHITKFRIKGSIQRM--KQN 165
            L    KDQV+K   +       Q+ +   E+K Q  L  +    +  I+   +++  K+ 
Sbjct: 2678 LDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEE 2737

Query: 166  LMGIQTDSIDLREKMRRELT---------LGQIRSSTMSNPDHFPQLLLPKDQVSGKAVC 216
             +  Q   IDL +  + EL          L +++ + M N  +  QL    ++  GK   
Sbjct: 2738 CLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKL 2797

Query: 217  LIEEISSTEIQVEMKMPAYELKIVHDHSEKPLKIELKVELPGINSVSLCDLSVSEGTTEP 276
            LI+  S  +++ E ++   EL  +    EK              + ++ D  V E TTE 
Sbjct: 2798 LIK--SCKQLEEEKEILQKELSQLQAAQEKQ------------KTGTVMDTKVDELTTEI 2843

Query: 277  QAL 279
            + L
Sbjct: 2844 KEL 2846


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,805,437
Number of Sequences: 37866
Number of extensions: 490984
Number of successful extensions: 1610
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1606
Number of HSP's gapped (non-prelim): 10
length of query: 288
length of database: 18,247,518
effective HSP length: 101
effective length of query: 187
effective length of database: 14,423,052
effective search space: 2697110724
effective search space used: 2697110724
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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