Search of human proteins with 4505143

Search of human proteins with 4505143

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505143 cytosolic malic enzyme 1 [Homo sapiens]
         (572 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505143 cytosolic malic enzyme 1 [Homo sapiens]                   1144   0.0  
gi|239049447 mitochondrial malic enzyme 3 [Homo sapiens]              851   0.0  
gi|62420882 mitochondrial malic enzyme 3 [Homo sapiens]               851   0.0  
gi|62420880 mitochondrial malic enzyme 3 [Homo sapiens]               851   0.0  
gi|4505145 malic enzyme 2, NAD(+)-dependent, mitochondrial [Homo...   654   0.0  
gi|51479145 brefeldin A-inhibited guanine nucleotide-exchange pr...    34   0.32 
gi|38569428 ankyrin repeat domain protein 5 [Homo sapiens]             31   2.7  
gi|38569426 ankyrin repeat domain protein 5 [Homo sapiens]             31   2.7  
gi|41872583 Rho-associated, coiled-coil containing protein kinas...    30   4.6  
gi|169164468 PREDICTED: similar to hCG1642995 [Homo sapiens]           30   4.6  
gi|239747951 PREDICTED: similar to hCG1642995 [Homo sapiens]           30   4.6  
gi|239741846 PREDICTED: similar to DnaJ (Hsp40) homolog, subfami...    30   4.6  
gi|18375660 protein tyrosine phosphatase, non-receptor type 7 is...    30   7.8  
gi|18375658 protein tyrosine phosphatase, non-receptor type 7 is...    30   7.8  
gi|65507403 SEC15-like 1 isoform a [Homo sapiens]                      30   7.8  
gi|62243652 SEC15-like 1 isoform b [Homo sapiens]                      30   7.8  

>gi|4505143 cytosolic malic enzyme 1 [Homo sapiens]
          Length = 572

 Score = 1144 bits (2960), Expect = 0.0
 Identities = 572/572 (100%), Positives = 572/572 (100%)

Query: 1   MEPEAPRRRHTHQRGYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVK 60
           MEPEAPRRRHTHQRGYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVK
Sbjct: 1   MEPEAPRRRHTHQRGYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVK 60

Query: 61  NFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKP 120
           NFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKP
Sbjct: 61  NFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKP 120

Query: 121 RGLFITIHDRGHIASVLNAWPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTAC 180
           RGLFITIHDRGHIASVLNAWPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTAC
Sbjct: 121 RGLFITIHDRGHIASVLNAWPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTAC 180

Query: 181 GGMNPQECLPVILDVGTENEELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNC 240
           GGMNPQECLPVILDVGTENEELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNC
Sbjct: 181 GGMNPQECLPVILDVGTENEELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNC 240

Query: 241 LIQFEDFANVNAFRLLNKYRNQYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTILFQ 300
           LIQFEDFANVNAFRLLNKYRNQYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTILFQ
Sbjct: 241 LIQFEDFANVNAFRLLNKYRNQYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTILFQ 300

Query: 301 GAGEAALGIAHLIVMALEKEGLPKEKAIKKIWLVDSKGLIVKGRASLTQEKEKFAHEHEE 360
           GAGEAALGIAHLIVMALEKEGLPKEKAIKKIWLVDSKGLIVKGRASLTQEKEKFAHEHEE
Sbjct: 301 GAGEAALGIAHLIVMALEKEGLPKEKAIKKIWLVDSKGLIVKGRASLTQEKEKFAHEHEE 360

Query: 361 MKNLEAIVQEIKPTALIGVAAIGGAFSEQILKDMAAFNERPIIFALSNPTSKAECSAEQC 420
           MKNLEAIVQEIKPTALIGVAAIGGAFSEQILKDMAAFNERPIIFALSNPTSKAECSAEQC
Sbjct: 361 MKNLEAIVQEIKPTALIGVAAIGGAFSEQILKDMAAFNERPIIFALSNPTSKAECSAEQC 420

Query: 421 YKITKGRAIFASGSPFDPVTLPNGQTLYPGQGNNSYVFPGVALGVVACGLRQITDNIFLT 480
           YKITKGRAIFASGSPFDPVTLPNGQTLYPGQGNNSYVFPGVALGVVACGLRQITDNIFLT
Sbjct: 421 YKITKGRAIFASGSPFDPVTLPNGQTLYPGQGNNSYVFPGVALGVVACGLRQITDNIFLT 480

Query: 481 TAEVIAQQVSDKHLEEGRLYPPLNTIRDVSLKIAEKIVKDAYQEKTATVYPEPQNKEAFV 540
           TAEVIAQQVSDKHLEEGRLYPPLNTIRDVSLKIAEKIVKDAYQEKTATVYPEPQNKEAFV
Sbjct: 481 TAEVIAQQVSDKHLEEGRLYPPLNTIRDVSLKIAEKIVKDAYQEKTATVYPEPQNKEAFV 540

Query: 541 RSQMYSTDYDQILPDCYSWPEEVQKIQTKVDQ 572
           RSQMYSTDYDQILPDCYSWPEEVQKIQTKVDQ
Sbjct: 541 RSQMYSTDYDQILPDCYSWPEEVQKIQTKVDQ 572


>gi|239049447 mitochondrial malic enzyme 3 [Homo sapiens]
          Length = 604

 Score =  851 bits (2199), Expect = 0.0
 Identities = 404/556 (72%), Positives = 485/556 (87%)

Query: 13  QRGYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRY 72
           +RGY +TRNPHLNK +AFTLEER QL IHGL+PP F SQ++Q+LR+++ +E   SD D+Y
Sbjct: 48  KRGYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKY 107

Query: 73  LLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGH 132
           ++LM LQDRNEKLFYRVLTSD+EKFMPIVYTPTVGLACQ Y L FR+PRGLFITIHD+GH
Sbjct: 108 IILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGH 167

Query: 133 IASVLNAWPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVI 192
           +A++LN+WPED IKA+VVTDGERILGLGDLGC GMGIPVGKLALYTACGG+NPQ+CLPV+
Sbjct: 168 LATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVL 227

Query: 193 LDVGTENEELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNCLIQFEDFANVNA 252
           LDVGT NEELL+DPLYIGL+ +RV G  YDD LDEFM+AV+ K+G+NCLIQFEDFAN NA
Sbjct: 228 LDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANA 287

Query: 253 FRLLNKYRNQYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTILFQGAGEAALGIAHL 312
           FRLLNKYRN+YC FNDDIQGTASVAVAG+LAALRITKNKLS+   +FQGAGEAA+GIAHL
Sbjct: 288 FRLLNKYRNKYCMFNDDIQGTASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHL 347

Query: 313 IVMALEKEGLPKEKAIKKIWLVDSKGLIVKGRASLTQEKEKFAHEHEEMKNLEAIVQEIK 372
           +VMALEKEG+PK +A +KIW+VDSKGLIVKGR+ L  EKE FA +H E+ +LE +V+ +K
Sbjct: 348 LVMALEKEGVPKAEATRKIWMVDSKGLIVKGRSHLNHEKEMFAQDHPEVNSLEEVVRLVK 407

Query: 373 PTALIGVAAIGGAFSEQILKDMAAFNERPIIFALSNPTSKAECSAEQCYKITKGRAIFAS 432
           PTA+IGVAAI GAF+EQIL+DMA+F+ERPIIFALSNPTSKAEC+AE+CY++T+GR IFAS
Sbjct: 408 PTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFAS 467

Query: 433 GSPFDPVTLPNGQTLYPGQGNNSYVFPGVALGVVACGLRQITDNIFLTTAEVIAQQVSDK 492
           GSPF  VTL +G+T  PGQGNN+YVFPGVALGV+A G+R I D IFL TAE IAQ+VS++
Sbjct: 468 GSPFKSVTLEDGKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQ 527

Query: 493 HLEEGRLYPPLNTIRDVSLKIAEKIVKDAYQEKTATVYPEPQNKEAFVRSQMYSTDYDQI 552
           HL +GRLYPPL+TIRDVSL+IA K++  AY+   A+ YPEP++KEAFVRS +Y+ DYD  
Sbjct: 528 HLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEPKDKEAFVRSLVYTPDYDSF 587

Query: 553 LPDCYSWPEEVQKIQT 568
             D Y+WP+E   +QT
Sbjct: 588 TLDSYTWPKEAMNVQT 603


>gi|62420882 mitochondrial malic enzyme 3 [Homo sapiens]
          Length = 604

 Score =  851 bits (2199), Expect = 0.0
 Identities = 404/556 (72%), Positives = 485/556 (87%)

Query: 13  QRGYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRY 72
           +RGY +TRNPHLNK +AFTLEER QL IHGL+PP F SQ++Q+LR+++ +E   SD D+Y
Sbjct: 48  KRGYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKY 107

Query: 73  LLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGH 132
           ++LM LQDRNEKLFYRVLTSD+EKFMPIVYTPTVGLACQ Y L FR+PRGLFITIHD+GH
Sbjct: 108 IILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGH 167

Query: 133 IASVLNAWPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVI 192
           +A++LN+WPED IKA+VVTDGERILGLGDLGC GMGIPVGKLALYTACGG+NPQ+CLPV+
Sbjct: 168 LATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVL 227

Query: 193 LDVGTENEELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNCLIQFEDFANVNA 252
           LDVGT NEELL+DPLYIGL+ +RV G  YDD LDEFM+AV+ K+G+NCLIQFEDFAN NA
Sbjct: 228 LDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANA 287

Query: 253 FRLLNKYRNQYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTILFQGAGEAALGIAHL 312
           FRLLNKYRN+YC FNDDIQGTASVAVAG+LAALRITKNKLS+   +FQGAGEAA+GIAHL
Sbjct: 288 FRLLNKYRNKYCMFNDDIQGTASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHL 347

Query: 313 IVMALEKEGLPKEKAIKKIWLVDSKGLIVKGRASLTQEKEKFAHEHEEMKNLEAIVQEIK 372
           +VMALEKEG+PK +A +KIW+VDSKGLIVKGR+ L  EKE FA +H E+ +LE +V+ +K
Sbjct: 348 LVMALEKEGVPKAEATRKIWMVDSKGLIVKGRSHLNHEKEMFAQDHPEVNSLEEVVRLVK 407

Query: 373 PTALIGVAAIGGAFSEQILKDMAAFNERPIIFALSNPTSKAECSAEQCYKITKGRAIFAS 432
           PTA+IGVAAI GAF+EQIL+DMA+F+ERPIIFALSNPTSKAEC+AE+CY++T+GR IFAS
Sbjct: 408 PTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFAS 467

Query: 433 GSPFDPVTLPNGQTLYPGQGNNSYVFPGVALGVVACGLRQITDNIFLTTAEVIAQQVSDK 492
           GSPF  VTL +G+T  PGQGNN+YVFPGVALGV+A G+R I D IFL TAE IAQ+VS++
Sbjct: 468 GSPFKSVTLEDGKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQ 527

Query: 493 HLEEGRLYPPLNTIRDVSLKIAEKIVKDAYQEKTATVYPEPQNKEAFVRSQMYSTDYDQI 552
           HL +GRLYPPL+TIRDVSL+IA K++  AY+   A+ YPEP++KEAFVRS +Y+ DYD  
Sbjct: 528 HLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEPKDKEAFVRSLVYTPDYDSF 587

Query: 553 LPDCYSWPEEVQKIQT 568
             D Y+WP+E   +QT
Sbjct: 588 TLDSYTWPKEAMNVQT 603


>gi|62420880 mitochondrial malic enzyme 3 [Homo sapiens]
          Length = 604

 Score =  851 bits (2199), Expect = 0.0
 Identities = 404/556 (72%), Positives = 485/556 (87%)

Query: 13  QRGYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRY 72
           +RGY +TRNPHLNK +AFTLEER QL IHGL+PP F SQ++Q+LR+++ +E   SD D+Y
Sbjct: 48  KRGYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKY 107

Query: 73  LLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGH 132
           ++LM LQDRNEKLFYRVLTSD+EKFMPIVYTPTVGLACQ Y L FR+PRGLFITIHD+GH
Sbjct: 108 IILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGH 167

Query: 133 IASVLNAWPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVI 192
           +A++LN+WPED IKA+VVTDGERILGLGDLGC GMGIPVGKLALYTACGG+NPQ+CLPV+
Sbjct: 168 LATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVL 227

Query: 193 LDVGTENEELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNCLIQFEDFANVNA 252
           LDVGT NEELL+DPLYIGL+ +RV G  YDD LDEFM+AV+ K+G+NCLIQFEDFAN NA
Sbjct: 228 LDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANA 287

Query: 253 FRLLNKYRNQYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTILFQGAGEAALGIAHL 312
           FRLLNKYRN+YC FNDDIQGTASVAVAG+LAALRITKNKLS+   +FQGAGEAA+GIAHL
Sbjct: 288 FRLLNKYRNKYCMFNDDIQGTASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHL 347

Query: 313 IVMALEKEGLPKEKAIKKIWLVDSKGLIVKGRASLTQEKEKFAHEHEEMKNLEAIVQEIK 372
           +VMALEKEG+PK +A +KIW+VDSKGLIVKGR+ L  EKE FA +H E+ +LE +V+ +K
Sbjct: 348 LVMALEKEGVPKAEATRKIWMVDSKGLIVKGRSHLNHEKEMFAQDHPEVNSLEEVVRLVK 407

Query: 373 PTALIGVAAIGGAFSEQILKDMAAFNERPIIFALSNPTSKAECSAEQCYKITKGRAIFAS 432
           PTA+IGVAAI GAF+EQIL+DMA+F+ERPIIFALSNPTSKAEC+AE+CY++T+GR IFAS
Sbjct: 408 PTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFAS 467

Query: 433 GSPFDPVTLPNGQTLYPGQGNNSYVFPGVALGVVACGLRQITDNIFLTTAEVIAQQVSDK 492
           GSPF  VTL +G+T  PGQGNN+YVFPGVALGV+A G+R I D IFL TAE IAQ+VS++
Sbjct: 468 GSPFKSVTLEDGKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQ 527

Query: 493 HLEEGRLYPPLNTIRDVSLKIAEKIVKDAYQEKTATVYPEPQNKEAFVRSQMYSTDYDQI 552
           HL +GRLYPPL+TIRDVSL+IA K++  AY+   A+ YPEP++KEAFVRS +Y+ DYD  
Sbjct: 528 HLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEPKDKEAFVRSLVYTPDYDSF 587

Query: 553 LPDCYSWPEEVQKIQT 568
             D Y+WP+E   +QT
Sbjct: 588 TLDSYTWPKEAMNVQT 603


>gi|4505145 malic enzyme 2, NAD(+)-dependent, mitochondrial [Homo
           sapiens]
          Length = 584

 Score =  654 bits (1686), Expect = 0.0
 Identities = 311/560 (55%), Positives = 411/560 (73%), Gaps = 3/560 (0%)

Query: 5   APRRRHTHQRGYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEH 64
           A R  H  ++G  L  NP  NK +AFTL+ERQ L + GLLPP   +Q+IQ LR  +N + 
Sbjct: 15  ACRHLHIKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKK 74

Query: 65  LNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLF 124
           + S  ++Y+ +M +Q+RNEKLFYR+L  DIE  MPIVYTPTVGLAC QY  +FR+P+GLF
Sbjct: 75  MTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLF 134

Query: 125 ITIHDRGHIASVLNAWPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMN 184
           I+I DRGH+ S+++ WPE+ +KA+VVTDGERILGLGDLG  GMGIPVGKL LYTAC G+ 
Sbjct: 135 ISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIR 194

Query: 185 PQECLPVILDVGTENEELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNCLIQF 244
           P  CLPV +DVGT+N  LLKDP Y+GL Q+R R  +YDD +DEFM+A++ +YG N LIQF
Sbjct: 195 PDRCLPVCIDVGTDNIALLKDPFYMGLYQKRDRTQQYDDLIDEFMKAITDRYGRNTLIQF 254

Query: 245 EDFANVNAFRLLNKYRNQYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTILFQGAGE 304
           EDF N NAFR L KYR +YCTFNDDIQGTA+VA+AGLLAA ++    +S+  ILF GAGE
Sbjct: 255 EDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVISKPISEHKILFLGAGE 314

Query: 305 AALGIAHLIVMALEKEGLPKEKAIKKIWLVDSKGLIVKGR-ASLTQEKEKFAHEHEEM-- 361
           AALGIA+LIVM++ + GL +++A KKIW+ D  GL+VKGR A +   +E F H   E   
Sbjct: 315 AALGIANLIVMSMVENGLSEQEAQKKIWMFDKYGLLVKGRKAKIDSYQEPFTHSAPESIP 374

Query: 362 KNLEAIVQEIKPTALIGVAAIGGAFSEQILKDMAAFNERPIIFALSNPTSKAECSAEQCY 421
              E  V  +KP+ +IGVA  G  F+  +++ MA+ NERP+IFALSNPT++AEC+AE+ Y
Sbjct: 375 DTFEDAVNILKPSTIIGVAGAGRLFTPDVIRAMASINERPVIFALSNPTAQAECTAEEAY 434

Query: 422 KITKGRAIFASGSPFDPVTLPNGQTLYPGQGNNSYVFPGVALGVVACGLRQITDNIFLTT 481
            +T+GR +FASGSPF PV L +G+   PGQGNN Y+FPGVAL V+ C  R I+D++FL  
Sbjct: 435 TLTEGRCLFASGSPFGPVKLTDGRVFTPGQGNNVYIFPGVALAVILCNTRHISDSVFLEA 494

Query: 482 AEVIAQQVSDKHLEEGRLYPPLNTIRDVSLKIAEKIVKDAYQEKTATVYPEPQNKEAFVR 541
           A+ +  Q++D+ L +GRLYPPL  I++VS+ IA K+ +  Y  K A  YPEP++K  +V+
Sbjct: 495 AKALTSQLTDEELAQGRLYPPLANIQEVSINIAIKVTEYLYANKMAFRYPEPEDKAKYVK 554

Query: 542 SQMYSTDYDQILPDCYSWPE 561
            + + ++YD +LPD Y WPE
Sbjct: 555 ERTWRSEYDSLLPDVYEWPE 574


>gi|51479145 brefeldin A-inhibited guanine nucleotide-exchange
           protein 1 [Homo sapiens]
          Length = 1849

 Score = 34.3 bits (77), Expect = 0.32
 Identities = 31/111 (27%), Positives = 56/111 (50%), Gaps = 2/111 (1%)

Query: 282 LAALRITKNKLSDQTILFQGAGEAALGIAHLIVMALEKEGLPKEKAIKKIWLVDSKGLIV 341
           L A  I +  ++D + + QG G   LG++++  ++L K+GL    +I K  +  SK   V
Sbjct: 573 LNAANIFERLVNDLSKIAQGRGSQELGMSNVQELSLRKKGLECLVSILKCMVEWSKDQYV 632

Query: 342 KGRASLTQEKEK-FAHEHEEMKNLEAIVQEIKPTALIGVAAIG-GAFSEQI 390
              +  T  +EK    E  E+K+ E I +     +L   ++ G G++S Q+
Sbjct: 633 NPNSQTTLGQEKPSEQEMSEIKHPETINRYGSLNSLESTSSSGIGSYSTQM 683


>gi|38569428 ankyrin repeat domain protein 5 [Homo sapiens]
          Length = 776

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 2/64 (3%)

Query: 489 VSDKHLEEGRLYPPLNTIRDVSLKIAEKIVKDAYQEKTATVYPEPQNKEAFVRSQMYSTD 548
           ++DK LE  ++Y  L  +R+   K  EK+ K  Y E     Y EP N  + +     S D
Sbjct: 3   LADKRLENLQIYKVLQCVRNKDKKQIEKLTKLGYPE--LINYTEPINGLSALHLASVSND 60

Query: 549 YDQI 552
            D +
Sbjct: 61  IDMV 64


>gi|38569426 ankyrin repeat domain protein 5 [Homo sapiens]
          Length = 776

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 2/64 (3%)

Query: 489 VSDKHLEEGRLYPPLNTIRDVSLKIAEKIVKDAYQEKTATVYPEPQNKEAFVRSQMYSTD 548
           ++DK LE  ++Y  L  +R+   K  EK+ K  Y E     Y EP N  + +     S D
Sbjct: 3   LADKRLENLQIYKVLQCVRNKDKKQIEKLTKLGYPE--LINYTEPINGLSALHLASVSND 60

Query: 549 YDQI 552
            D +
Sbjct: 61  IDMV 64


>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
            [Homo sapiens]
          Length = 1388

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 37/126 (29%), Positives = 51/126 (40%), Gaps = 22/126 (17%)

Query: 281  LLAALRITKNKLSDQTILFQGAGEAALGIAHLIVMALEKEGLPKEKAIKKIWLVDSKGLI 340
            L A L IT  K   + +        A  IA      LEKE + KE  IK++     + L 
Sbjct: 911  LAAQLEITLTKADSEQL--------ARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELT 962

Query: 341  VKGRA---------SLTQEKEKFAHEHEEMKNLEAIVQE----IKPTALIGVAAIGGAFS 387
             K            +LT +    A+E EE+ N    VQE    +K    I  AAI   F 
Sbjct: 963  EKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEE-ISAAAIKAQFE 1021

Query: 388  EQILKD 393
            +Q+L +
Sbjct: 1022 KQLLTE 1027


>gi|169164468 PREDICTED: similar to hCG1642995 [Homo sapiens]
          Length = 181

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 12/30 (40%), Positives = 21/30 (70%)

Query: 503 LNTIRDVSLKIAEKIVKDAYQEKTATVYPE 532
           L  + D+  K+A+K V+ AY++K ++ YPE
Sbjct: 3   LYALLDIEEKVADKEVEKAYRQKASSCYPE 32


>gi|239747951 PREDICTED: similar to hCG1642995 [Homo sapiens]
          Length = 181

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 12/30 (40%), Positives = 21/30 (70%)

Query: 503 LNTIRDVSLKIAEKIVKDAYQEKTATVYPE 532
           L  + D+  K+A+K V+ AY++K ++ YPE
Sbjct: 3   LYALLDIEEKVADKEVEKAYRQKASSCYPE 32


>gi|239741846 PREDICTED: similar to DnaJ (Hsp40) homolog, subfamily
           C, member 17 [Homo sapiens]
          Length = 181

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 12/30 (40%), Positives = 21/30 (70%)

Query: 503 LNTIRDVSLKIAEKIVKDAYQEKTATVYPE 532
           L  + D+  K+A+K V+ AY++K ++ YPE
Sbjct: 3   LYALLDIEEKVADKEVEKAYRQKASSCYPE 32


>gi|18375660 protein tyrosine phosphatase, non-receptor type 7
           isoform 2 [Homo sapiens]
          Length = 399

 Score = 29.6 bits (65), Expect = 7.8
 Identities = 22/65 (33%), Positives = 29/65 (44%), Gaps = 4/65 (6%)

Query: 479 LTTAEVIAQQVSDKHLEEGRLYPPLNTIRDVSLKIAEKIVKDAYQEKTATVYPEPQNKEA 538
           LT   +  Q  S K LEE  L  P N +    L I     KD Y+    T+ P PQ++  
Sbjct: 121 LTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYK----TILPNPQSRVC 176

Query: 539 FVRSQ 543
             R+Q
Sbjct: 177 LGRAQ 181


>gi|18375658 protein tyrosine phosphatase, non-receptor type 7
           isoform 1 [Homo sapiens]
          Length = 360

 Score = 29.6 bits (65), Expect = 7.8
 Identities = 22/65 (33%), Positives = 29/65 (44%), Gaps = 4/65 (6%)

Query: 479 LTTAEVIAQQVSDKHLEEGRLYPPLNTIRDVSLKIAEKIVKDAYQEKTATVYPEPQNKEA 538
           LT   +  Q  S K LEE  L  P N +    L I     KD Y+    T+ P PQ++  
Sbjct: 82  LTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYK----TILPNPQSRVC 137

Query: 539 FVRSQ 543
             R+Q
Sbjct: 138 LGRAQ 142


>gi|65507403 SEC15-like 1 isoform a [Homo sapiens]
          Length = 804

 Score = 29.6 bits (65), Expect = 7.8
 Identities = 17/46 (36%), Positives = 25/46 (54%)

Query: 503 LNTIRDVSLKIAEKIVKDAYQEKTATVYPEPQNKEAFVRSQMYSTD 548
           L +IR  S KI E  +K A  +KT +V  + QNK  F ++   + D
Sbjct: 204 LESIRKHSDKIGETAMKQAQHQKTFSVSLQKQNKMKFGKNMYINRD 249


>gi|62243652 SEC15-like 1 isoform b [Homo sapiens]
          Length = 799

 Score = 29.6 bits (65), Expect = 7.8
 Identities = 17/46 (36%), Positives = 25/46 (54%)

Query: 503 LNTIRDVSLKIAEKIVKDAYQEKTATVYPEPQNKEAFVRSQMYSTD 548
           L +IR  S KI E  +K A  +KT +V  + QNK  F ++   + D
Sbjct: 199 LESIRKHSDKIGETAMKQAQHQKTFSVSLQKQNKMKFGKNMYINRD 244


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,380,355
Number of Sequences: 37866
Number of extensions: 954081
Number of successful extensions: 2070
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2057
Number of HSP's gapped (non-prelim): 16
length of query: 572
length of database: 18,247,518
effective HSP length: 108
effective length of query: 464
effective length of database: 14,157,990
effective search space: 6569307360
effective search space used: 6569307360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.