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Search of human proteins with 4505029
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505029 leukotriene A4 hydrolase [Homo sapiens]
(611 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505029 leukotriene A4 hydrolase [Homo sapiens] 1248 0.0
gi|40316915 arginyl aminopeptidase [Homo sapiens] 378 e-104
gi|54020718 arginyl aminopeptidase (aminopeptidase B)-like 1 [Ho... 244 2e-64
gi|61742777 leucyl/cystinyl aminopeptidase isoform 1 [Homo sapiens] 118 2e-26
gi|61742775 leucyl/cystinyl aminopeptidase isoform 2 [Homo sapiens] 118 2e-26
gi|158937236 aminopeptidase puromycin sensitive [Homo sapiens] 115 2e-25
gi|157266300 membrane alanine aminopeptidase precursor [Homo sap... 100 4e-21
gi|194239713 laeverin [Homo sapiens] 100 4e-21
gi|132814467 glutamyl aminopeptidase [Homo sapiens] 93 6e-19
gi|94818891 type 1 tumor necrosis factor receptor shedding amino... 89 1e-17
gi|94818901 type 1 tumor necrosis factor receptor shedding amino... 89 1e-17
gi|7019561 thyrotropin-releasing hormone degrading enzyme [Homo ... 85 2e-16
gi|194306629 endoplasmic reticulum aminopeptidase 2 [Homo sapiens] 82 2e-15
gi|11641261 endoplasmic reticulum aminopeptidase 2 [Homo sapiens] 82 2e-15
gi|24432058 aminopeptidase O [Homo sapiens] 49 2e-05
gi|14196471 protocadherin gamma subfamily A, 5 isoform 2 precurs... 32 2.2
gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precurs... 32 2.2
gi|194097462 actin-like 9 [Homo sapiens] 31 3.8
gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens] 30 5.0
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap... 30 8.5
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap... 30 8.5
>gi|4505029 leukotriene A4 hydrolase [Homo sapiens]
Length = 611
Score = 1248 bits (3230), Expect = 0.0
Identities = 611/611 (100%), Positives = 611/611 (100%)
Query: 1 MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDL 60
MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDL
Sbjct: 1 MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDL 60
Query: 61 TIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLT 120
TIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLT
Sbjct: 61 TIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLT 120
Query: 121 PEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETP 180
PEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETP
Sbjct: 121 PEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETP 180
Query: 181 DPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETES 240
DPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETES
Sbjct: 181 DPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETES 240
Query: 241 MLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISH 300
MLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISH
Sbjct: 241 MLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISH 300
Query: 301 SWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGET 360
SWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGET
Sbjct: 301 SWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGET 360
Query: 361 HPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSI 420
HPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSI
Sbjct: 361 HPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSI 420
Query: 421 TTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAK 480
TTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAK
Sbjct: 421 TTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAK 480
Query: 481 EDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWL 540
EDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWL
Sbjct: 481 EDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWL 540
Query: 541 RLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVT 600
RLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVT
Sbjct: 541 RLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVT 600
Query: 601 AMLVGKDLKVD 611
AMLVGKDLKVD
Sbjct: 601 AMLVGKDLKVD 611
>gi|40316915 arginyl aminopeptidase [Homo sapiens]
Length = 650
Score = 378 bits (970), Expect = e-104
Identities = 226/597 (37%), Positives = 334/597 (55%), Gaps = 36/597 (6%)
Query: 3 EIVDTCSLASPASVCRTKHLHLRCSVDFT-------RRTLTGTAALTVQSQE-DNLRSLV 54
+ VD S AS HLHL +F R L+GTA L ++ E + L
Sbjct: 21 QAVDVAS-ASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLSGTAVLDLRCLEPEGAAELR 79
Query: 55 LDTKD-LTIEKVVIN----GQEVKYA-----LGERQSYKGSPMEISLPIALSKNQEIVIE 104
LD+ L + + G E A + S+ G + +S P + + +
Sbjct: 80 LDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQALCVSFPQPCRAAERLQVL 139
Query: 105 ISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVP 164
+++ + + WL PEQT+GK+ P++++Q QA+ RA PC DTP+VK Y+A + VP
Sbjct: 140 LTYRVG-EGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVP 198
Query: 165 KELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSE 224
A+MSA T + P++ ++ Q PIP YLIAL +G L S ++GPR+ VW+E
Sbjct: 199 DGFTAVMSA----STWEKRGPNKFFFQMCQ--PIPSYLIALAIGDLVSAEVGPRSRVWAE 252
Query: 225 KEQVEKSAYEFSET-ESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTL 283
++ + E++ E L E L GPYVWG+YDLL +PPSFP+GGMENPCLTFVTP L
Sbjct: 253 PCLIDAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCL 312
Query: 284 LAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNA 343
LAGD+SL++VI HEISHSW GNLVTN W FWLNEG T+Y +R I LFG + A
Sbjct: 313 LAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEA 372
Query: 344 LGGWGELQNSVKTFGETHPFTKLVVDL-TDIDPDVAYSSVPYEKGFALLFYLEQLLGGPE 402
G L+ + GE +P KL V + +DPD Y+ PYEKGF + YL L+G +
Sbjct: 373 ATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQD 432
Query: 403 IFLGFLKAYVEKFSYKSITTDDWKDFLYSYF----KDKVDVLNQVDWNAWLYSPGLPPIK 458
F FLKAYV +F ++SI DD+ DF YF K +VD++ +++ WL +PG PP
Sbjct: 433 QFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGWPPYL 492
Query: 459 PNYDM--TLTNACIALSQRWITAKEDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLG 516
P+ +L L+Q W A+E D+ + A + ++QL FL + LQ++PLP G
Sbjct: 493 PDLSPGDSLMKPAEELAQLW-AAEELDMKAIEAVAISPWKTYQLVYFLDKILQKSPLPPG 551
Query: 517 HIKRMQEVY-NFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLF 572
++K++ + Y + + N+E+R RW ++ +++ ++ + QG+ K+T PL+
Sbjct: 552 NVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVKEFLHNQGKQKYTLPLY 608
>gi|54020718 arginyl aminopeptidase (aminopeptidase B)-like 1 [Homo
sapiens]
Length = 494
Score = 244 bits (622), Expect = 2e-64
Identities = 142/420 (33%), Positives = 217/420 (51%), Gaps = 11/420 (2%)
Query: 189 IYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFS-ETESMLKIAED 247
++ F + P+P YL+ALV G L+ IGPR+ VW+E + + + S E L AE
Sbjct: 14 VFHFHMEHPVPAYLVALVAGDLKPADIGPRSRVWAEPCLLPTATSKLSGAVEQWLSAAER 73
Query: 248 LGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLV 307
L GPY+WG+YD++ LPPSFP MENPCLTF+ ++L D+ L + HE++HSW GN V
Sbjct: 74 LYGPYMWGRYDIVFLPPSFPIVAMENPCLTFIISSILESDEFLVIDVIHEVAHSWFGNAV 133
Query: 308 TNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLV 367
TN TW+ WL+EG Y +R I +G F L +K GE P +KL
Sbjct: 134 TNATWEEMWLSEGLATYAQRRITTETYGAAFTCLETAFRLDALHRQMKLLGEDSPVSKLQ 193
Query: 368 VDL-TDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWK 426
V L ++P + YEKG+ ++YL QL G P+ F FL+AYVEK+ + S+ D
Sbjct: 194 VKLEPGVNPSHLMNLFTYEKGYCFVYYLSQLCGDPQRFDDFLRAYVEKYKFTSVVAQDLL 253
Query: 427 DFLYSYF----KDKVDVLNQVDWNAWLYSPGLPPIKPNYDM--TLTNACIALSQRWITAK 480
D S+F + VD +++ WL + G P +P+ +LT AL Q W
Sbjct: 254 DSFLSFFPELKEQSVDCRAGLEFERWLNATGPPLAEPDLSQGSSLTRPVEALFQLWTAEP 313
Query: 481 EDD-LNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAIN-NSEIRFR 538
D S +A D+ + Q FL + L +PLP + + + Y+ + N+EIR R
Sbjct: 314 LDQAAASASAIDISKWRTFQTALFLDRLLDGSPLPQEVVMSLSKCYSSLLDSMNAEIRIR 373
Query: 539 WLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHP 598
WL++ +++ + + + Q +T PL++DL A+ + + + +HP
Sbjct: 374 WLQIVVRNDYYPDLHRVRRFLESQMSRMYTIPLYEDLCT-GALKSFALEVFYQTQGRLHP 432
>gi|61742777 leucyl/cystinyl aminopeptidase isoform 1 [Homo sapiens]
Length = 1025
Score = 118 bits (295), Expect = 2e-26
Identities = 116/456 (25%), Positives = 200/456 (43%), Gaps = 51/456 (11%)
Query: 29 DFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVV----INGQEVKYALGERQSYKG 84
+ T T G+ ++VQ+ + +++L + I +V ++ QE + + E +Y G
Sbjct: 184 NLTSMTFRGSVTISVQALQVTW-NIILHSTGHNISRVTFMSAVSSQEKQAEILE-YAYHG 241
Query: 85 SPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQT--SGKEHPYLFSQCQAIHCR 142
+ I P AL ++I + + SS + T S ++ + +Q + + R
Sbjct: 242 Q-IAIVAPEALLAGHNYTLKIEYSANISSSYYGFYGFSYTDESNEKKYFAATQFEPLAAR 300
Query: 143 AILPCQDTPSVKLTYTAEVSVPKELVALMS-------AIRDGETPDPEDPSRKIYKFIQK 195
+ PC D P+ K T+ ++ ++ AL + + DG D +F +
Sbjct: 301 SAFPCFDEPAFKATFIIKIIRDEQYTALSNMPKKSSVVLDDGLVQD---------EFSES 351
Query: 196 VPIPCYLIALVVGALE--SRQI-GPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPY 252
V + YL+A +VG ++ S+ + G +++ E++ + Y T +L+ ++ Y
Sbjct: 352 VKMSTYLVAFIVGEMKNLSQDVNGTLVSIYAVPEKIGQVHYALETTVKLLEFFQN----Y 407
Query: 253 VWGQYDL----LVLPPSFPYGGMEN-PCLTFVTPTLL--------AGDKSLSNVIAHEIS 299
QY L LV P F G MEN LTF TLL A K ++ +IAHE++
Sbjct: 408 FEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDSNTSSMADRKLVTKIIAHELA 467
Query: 300 HSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGE 359
H W GNLVT K W+ WLNEG ++E ++F E + + L + +
Sbjct: 468 HQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKIFKELSSYEDFLDARFKTMKK-DSLNS 526
Query: 360 THPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKS 419
+HP + V I+ + S+ Y KG +LL L+ L ++F + Y+ SY S
Sbjct: 527 SHPISSSVQSSEQIEE--MFDSLSYFKGSSLLLMLKTYL-SEDVFQHAVVLYLHNHSYAS 583
Query: 420 ITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLP 455
I +DD D +DV + W G P
Sbjct: 584 IQSDDLWDSFNEVTNQTLDVKRMM--KTWTLQKGFP 617
>gi|61742775 leucyl/cystinyl aminopeptidase isoform 2 [Homo sapiens]
Length = 1011
Score = 118 bits (295), Expect = 2e-26
Identities = 116/456 (25%), Positives = 200/456 (43%), Gaps = 51/456 (11%)
Query: 29 DFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVV----INGQEVKYALGERQSYKG 84
+ T T G+ ++VQ+ + +++L + I +V ++ QE + + E +Y G
Sbjct: 170 NLTSMTFRGSVTISVQALQVTW-NIILHSTGHNISRVTFMSAVSSQEKQAEILE-YAYHG 227
Query: 85 SPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQT--SGKEHPYLFSQCQAIHCR 142
+ I P AL ++I + + SS + T S ++ + +Q + + R
Sbjct: 228 Q-IAIVAPEALLAGHNYTLKIEYSANISSSYYGFYGFSYTDESNEKKYFAATQFEPLAAR 286
Query: 143 AILPCQDTPSVKLTYTAEVSVPKELVALMS-------AIRDGETPDPEDPSRKIYKFIQK 195
+ PC D P+ K T+ ++ ++ AL + + DG D +F +
Sbjct: 287 SAFPCFDEPAFKATFIIKIIRDEQYTALSNMPKKSSVVLDDGLVQD---------EFSES 337
Query: 196 VPIPCYLIALVVGALE--SRQI-GPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPY 252
V + YL+A +VG ++ S+ + G +++ E++ + Y T +L+ ++ Y
Sbjct: 338 VKMSTYLVAFIVGEMKNLSQDVNGTLVSIYAVPEKIGQVHYALETTVKLLEFFQN----Y 393
Query: 253 VWGQYDL----LVLPPSFPYGGMEN-PCLTFVTPTLL--------AGDKSLSNVIAHEIS 299
QY L LV P F G MEN LTF TLL A K ++ +IAHE++
Sbjct: 394 FEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDSNTSSMADRKLVTKIIAHELA 453
Query: 300 HSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGE 359
H W GNLVT K W+ WLNEG ++E ++F E + + L + +
Sbjct: 454 HQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKIFKELSSYEDFLDARFKTMKK-DSLNS 512
Query: 360 THPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKS 419
+HP + V I+ + S+ Y KG +LL L+ L ++F + Y+ SY S
Sbjct: 513 SHPISSSVQSSEQIEE--MFDSLSYFKGSSLLLMLKTYL-SEDVFQHAVVLYLHNHSYAS 569
Query: 420 ITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLP 455
I +DD D +DV + W G P
Sbjct: 570 IQSDDLWDSFNEVTNQTLDVKRMM--KTWTLQKGFP 603
>gi|158937236 aminopeptidase puromycin sensitive [Homo sapiens]
Length = 919
Score = 115 bits (287), Expect = 2e-25
Identities = 106/433 (24%), Positives = 176/433 (40%), Gaps = 25/433 (5%)
Query: 59 DLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQ-EIVIEISFETSPKSSALQ 117
D+ G E +A G + + +S P L + I+ E + K
Sbjct: 101 DIITASYAPEGDEEIHATGFNYQNEDEKVTLSFPSTLQTGTGTLKIDFVGELNDKMKGFY 160
Query: 118 WLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDG 177
SG+ +Q +A R PC D P++K T+ + VPK+ VAL +
Sbjct: 161 RSKYTTPSGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVID 220
Query: 178 ETPDPEDPSRKIYKFIQKVPIPCYLIALVVGA---LESR-QIGPRTLVWSEKEQVEKSAY 233
P P+D + KF + + YL+A VVG +E+R + G V++ + E+ +
Sbjct: 221 RKPYPDDENLVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKF 280
Query: 234 EFSETESMLKIAED-LGGPYVWGQYDLLVLPPSFPYGGMEN-PCLTFVTPTLLAGDKS-- 289
L +D PY + DL+ + F G MEN +T+ LL K+
Sbjct: 281 ALEVAAKTLPFYKDYFNVPYPLPKIDLIAIA-DFAAGAMENWGLVTYRETALLIDPKNSC 339
Query: 290 ------LSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNA 343
++ V+ HE++H W GNLVT + W H WLNEG ++E F E
Sbjct: 340 SSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQF 399
Query: 344 LGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEI 403
+ + +HP V +++D + ++ Y KG +++ L +G +
Sbjct: 400 VSADYTRAQELDALDNSHPIEVSVGHPSEVDE--IFDAISYSKGASVIRMLHDYIGDKDF 457
Query: 404 FLGFLKAYVEKFSYKSITTDD-WKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYD 462
G + Y+ KF K+ T+D W+ + K V+ N W G P I +
Sbjct: 458 KKG-MNMYLTKFQQKNAATEDLWESLENASGKPIAAVM-----NTWTKQMGFPLIYVEAE 511
Query: 463 MTLTNACIALSQR 475
+ + LSQ+
Sbjct: 512 QVEDDRLLRLSQK 524
>gi|157266300 membrane alanine aminopeptidase precursor [Homo
sapiens]
Length = 967
Score = 100 bits (249), Expect = 4e-21
Identities = 100/393 (25%), Positives = 164/393 (41%), Gaps = 28/393 (7%)
Query: 89 ISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFS-QCQAIHCRAILPC 147
+ L +L K+ + ++ FE + E G + + Q QA R PC
Sbjct: 164 VHLKGSLVKDSQYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPC 223
Query: 148 QDTPSVKLTYTAEVSVPKELVALMSAIRDG-ETPDPEDPSRKIYKFIQKVPIPCYLIALV 206
D P++K + + PK+L AL + + G TP PEDP+ + +F + YL+A +
Sbjct: 224 FDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFI 283
Query: 207 VGALE----SRQIGPRTLVWSEKEQVEKSA--YEFSETESMLKI-AEDLGGPYVWGQYDL 259
V + G +W+ + Y + T +L A PY + D
Sbjct: 284 VSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQ 343
Query: 260 LVLPPSFPYGGMEN-PCLTFVTPTLLAGDKSLSN--------VIAHEISHSWTGNLVTNK 310
+ LP F G MEN +T+ +LL S S+ VIAHE++H W GNLVT +
Sbjct: 344 IGLP-DFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIE 402
Query: 311 TWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQN--SVKTFGETHPFTKLVV 368
W+ WLNEG Y+E G + E + L ++ +V +HP +
Sbjct: 403 WWNDLWLNEGFASYVE--YLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPAS 460
Query: 369 DL-TDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYK-SITTDDWK 426
++ T + ++ Y KG ++L L L ++F L +Y+ F+Y+ +I + W
Sbjct: 461 EINTPAQISELFDAISYSKGASVLRMLSSFL-SEDVFKQGLASYLHTFAYQNTIYLNLWD 519
Query: 427 DFLYSYFKDKVDVLNQVD--WNAWLYSPGLPPI 457
+ + + V N W G P I
Sbjct: 520 HLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPVI 552
>gi|194239713 laeverin [Homo sapiens]
Length = 990
Score = 100 bits (249), Expect = 4e-21
Identities = 100/397 (25%), Positives = 158/397 (39%), Gaps = 27/397 (6%)
Query: 87 MEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILP 146
+E+S P+ + E+ + S +L G+ L SQ + R + P
Sbjct: 190 LELSEPLKPGSSYELQLSFSGLVKEDLREGLFLNVYTDQGERRALLASQLEPTFARYVFP 249
Query: 147 CQDTPSVKLTYTAEVSVPKELVAL--MSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIA 204
C D P++K T+ + VAL M + E D + F +P YL+A
Sbjct: 250 CFDEPALKATFNITMIHHPSYVALSNMPKLGQSEKEDVNGSKWTVTTFSTTPHMPTYLVA 309
Query: 205 LVV---GALESRQIGPRTLVWSEKEQVEKSAYEFSE--TESMLKIAEDLGG-PYVWGQYD 258
V+ + + G +W+ K+ + + +F+ T + EDL Y + D
Sbjct: 310 FVICDYDHVNRTERGKEIRIWARKDAIANGSADFALNITGPIFSFLEDLFNISYSLPKTD 369
Query: 259 LLVLPPSFPYGGMEN-PCLTFVTPTLLAGDKS--------LSNVIAHEISHSWTGNLVTN 309
++ LP SF MEN + F LL K +S V++HEI H W GNLVT
Sbjct: 370 IIALP-SFDNHAMENWGLMIFDESGLLLEPKDQLTEKKTLISYVVSHEIGHQWFGNLVTM 428
Query: 310 KTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGE--THPFTKLV 367
W++ WLNEG Y E + F K N + L N ++ T V
Sbjct: 429 NWWNNIWLNEGFASYFEFEVI-NYFNPKLPR-NEIFFSNILHNILREDHALVTRAVAMKV 486
Query: 368 VDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDD-WK 426
+ + + Y KG ++ L L +F+ LK+Y++ FSY + DD W+
Sbjct: 487 ENFKTSEIQELFDIFTYSKGASMARMLSCFL-NEHLFVSALKSYLKTFSYSNAEQDDLWR 545
Query: 427 DFLYSYFKDKVDVLNQVDWN---AWLYSPGLPPIKPN 460
F + +L N +W + G P I N
Sbjct: 546 HFQMAIDDQSTVILPATIKNIMDSWTHQSGFPVITLN 582
>gi|132814467 glutamyl aminopeptidase [Homo sapiens]
Length = 957
Score = 93.2 bits (230), Expect = 6e-19
Identities = 115/478 (24%), Positives = 191/478 (39%), Gaps = 62/478 (12%)
Query: 34 TLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPI 93
T TGT ++++ R L L ++ I + L E + G +++
Sbjct: 114 TYTGTVSISINLSAPT-RYLWLHLRETRITR-----------LPELKRPSGDQVQVRRCF 161
Query: 94 ALSKNQEIVIEISFETSPKSS-ALQWLTPE-----------------QTSGKEHPYLFSQ 135
K + +V+E E +P S L LT E +G+ + +
Sbjct: 162 EYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLNGSLVGFYRTTYTENGQVKSIVATD 221
Query: 136 CQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQK 195
+ R PC D P+ K TYT ++ PKE AL + E + +R ++ +
Sbjct: 222 HEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKWTRTTFE--KS 279
Query: 196 VPIPCYLIALVVGALES----RQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAED-LGG 250
VP+ YL+ V +S G ++ + EQ + Y + T+S+ E+
Sbjct: 280 VPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQKHTAEYAANITKSVFDYFEEYFAM 339
Query: 251 PYVWGQYDLLVLPPSFPYGGMEN-PCLTFVTPTLLAGDKS--------LSNVIAHEISHS 301
Y + D + +P F G MEN +T+ LL K ++ V+AHE+ H
Sbjct: 340 NYSLPKLDKIAIP-DFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQ 398
Query: 302 WTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGE---KFRHFNALGGWGELQNSVKTFG 358
W GN+VT W+ WLNEG + E G E + R L +Q +
Sbjct: 399 WFGNIVTMDWWEDLWLNEGFASFFE--FLGVNHAETDWQMRDQMLLEDVLPVQED-DSLM 455
Query: 359 ETHPFTKLVVDLTDIDPDVA-YSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSY 417
+HP ++V +T D + + + Y KG ++L LE + PE F + Y+EK+ +
Sbjct: 456 SSHP---IIVTVTTPDEITSVFDGISYSKGSSILRMLEDWI-KPENFQKGCQMYLEKYQF 511
Query: 418 KSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQR 475
K+ T D+ L ++ V +D W G P + N +T L R
Sbjct: 512 KNAKTSDFWAALEE--ASRLPVKEVMD--TWTRQMGYPVLNVNGVKNITQKRFLLDPR 565
>gi|94818891 type 1 tumor necrosis factor receptor shedding
aminopeptidase regulator isoform b [Homo sapiens]
Length = 941
Score = 89.0 bits (219), Expect = 1e-17
Identities = 98/443 (22%), Positives = 179/443 (40%), Gaps = 52/443 (11%)
Query: 21 HLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQ 80
H L + T T GT + + + + +++L + L I + + + GER
Sbjct: 62 HYDLLIHANLTTLTFWGTTKVEITASQPT-STIILHSHHLQISRATL-----RKGAGERL 115
Query: 81 SYKGSPM-------EISL----PIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEH 129
S + + +I+L P+ + +VI + S T G+
Sbjct: 116 SEEPLQVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELR 175
Query: 130 PYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMS-------AIRDGETPDP 182
+Q + R PC D P+ K +++ ++ +A+ + + +G D
Sbjct: 176 ILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDH 235
Query: 183 EDPSRKIYKFIQKVPIPCYLIALVVGALES----RQIGPRTLVWSEKEQVEKSAYEFSET 238
D + V + YL+A ++ ES + G + V++ +++ ++ Y
Sbjct: 236 FDVT---------VKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAA 286
Query: 239 ESMLKIAEDLGG-PYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNV---- 293
++L+ ED PY + DL +P F G MEN LT + L D S+
Sbjct: 287 VTLLEFYEDYFSIPYPLPKQDLAAIP-DFQSGAMENWGLTTYRESALLFDAEKSSASSKL 345
Query: 294 -----IAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWG 348
+AHE++H W GNLVT + W+ WLNEG ++E + + + + + G
Sbjct: 346 GITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFME-FVSVSVTHPELKVGDYFFGKC 404
Query: 349 ELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFL 408
V +HP + V + I + V Y+KG +L L + L + F +
Sbjct: 405 FDAMEVDALNSSHPVSTPVENPAQIRE--MFDDVSYDKGACILNMLREYLSA-DAFKSGI 461
Query: 409 KAYVEKFSYKSITTDDWKDFLYS 431
Y++K SYK+ +D D + S
Sbjct: 462 VQYLQKHSYKNTKNEDLWDSMAS 484
>gi|94818901 type 1 tumor necrosis factor receptor shedding
aminopeptidase regulator isoform a [Homo sapiens]
Length = 948
Score = 89.0 bits (219), Expect = 1e-17
Identities = 98/443 (22%), Positives = 179/443 (40%), Gaps = 52/443 (11%)
Query: 21 HLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQ 80
H L + T T GT + + + + +++L + L I + + + GER
Sbjct: 62 HYDLLIHANLTTLTFWGTTKVEITASQPT-STIILHSHHLQISRATL-----RKGAGERL 115
Query: 81 SYKGSPM-------EISL----PIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEH 129
S + + +I+L P+ + +VI + S T G+
Sbjct: 116 SEEPLQVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELR 175
Query: 130 PYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMS-------AIRDGETPDP 182
+Q + R PC D P+ K +++ ++ +A+ + + +G D
Sbjct: 176 ILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDH 235
Query: 183 EDPSRKIYKFIQKVPIPCYLIALVVGALES----RQIGPRTLVWSEKEQVEKSAYEFSET 238
D + V + YL+A ++ ES + G + V++ +++ ++ Y
Sbjct: 236 FDVT---------VKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAA 286
Query: 239 ESMLKIAEDLGG-PYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNV---- 293
++L+ ED PY + DL +P F G MEN LT + L D S+
Sbjct: 287 VTLLEFYEDYFSIPYPLPKQDLAAIP-DFQSGAMENWGLTTYRESALLFDAEKSSASSKL 345
Query: 294 -----IAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWG 348
+AHE++H W GNLVT + W+ WLNEG ++E + + + + + G
Sbjct: 346 GITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFME-FVSVSVTHPELKVGDYFFGKC 404
Query: 349 ELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFL 408
V +HP + V + I + V Y+KG +L L + L + F +
Sbjct: 405 FDAMEVDALNSSHPVSTPVENPAQIRE--MFDDVSYDKGACILNMLREYLSA-DAFKSGI 461
Query: 409 KAYVEKFSYKSITTDDWKDFLYS 431
Y++K SYK+ +D D + S
Sbjct: 462 VQYLQKHSYKNTKNEDLWDSMAS 484
>gi|7019561 thyrotropin-releasing hormone degrading enzyme [Homo
sapiens]
Length = 1024
Score = 85.1 bits (209), Expect = 2e-16
Identities = 93/372 (25%), Positives = 147/372 (39%), Gaps = 44/372 (11%)
Query: 134 SQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFI 193
+Q H R PC D P K T+ ++S+ + L + ET E+ F
Sbjct: 265 TQFSPTHARKAFPCFDEPIYKATF--KISIKHQATYLSLSNMPVETSVFEEDGWVTDHFS 322
Query: 194 QKVPIPCYLIALVVGALESRQIGPRTLV----WSEKEQVEKSA--YEFSETESMLKIAED 247
Q + Y +A + R+ ++ V ++ + + + + Y T+ +++ ED
Sbjct: 323 QTPLMSTYYLAWAICNFTYRETTTKSGVVVRLYARPDAIRRGSGDYALHITKRLIEFYED 382
Query: 248 -LGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSN---------VIAHE 297
PY + DLL +P PY MEN L+ + D S+S+ VI HE
Sbjct: 383 YFKVPYSLPKLDLLAVP-KHPYAAMENWGLSIFVEQRILLDPSVSSISYLLDVTMVIVHE 441
Query: 298 ISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKT- 356
I H W G+LVT W+ WL EG Y E G + + GW + T
Sbjct: 442 ICHQWFGDLVTPVWWEDVWLKEGFAHYFE------FVGTDYLY----PGWNMEKQRFLTD 491
Query: 357 ----------FGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLG 406
+HP ++ V+ TDID + + Y+KG AL+ L + G +F
Sbjct: 492 VLHEVMLLDGLASSHPVSQEVLQATDIDR--VFDWIAYKKGAALIRMLANFM-GHSVFQR 548
Query: 407 FLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLN-QVDWNAWLYSPGLPPIKPNYDMTL 465
L+ Y+ Y + +D + L K +N Q + W G P I + T
Sbjct: 549 GLQDYLTIHKYGNAARNDLWNTLSEALKRNGKYVNIQEVMDQWTLQMGYPVITILGNTTA 608
Query: 466 TNACIALSQRWI 477
N I Q +I
Sbjct: 609 ENRIIITQQHFI 620
>gi|194306629 endoplasmic reticulum aminopeptidase 2 [Homo sapiens]
Length = 960
Score = 81.6 bits (200), Expect = 2e-15
Identities = 91/394 (23%), Positives = 158/394 (40%), Gaps = 29/394 (7%)
Query: 53 LVLDTKDLTIEKVVINGQEVKYALGERQSYK------GSPMEISLPIALSKNQEIVIEIS 106
++L +KDL I + +E + + K + + +P L+ + + + +
Sbjct: 108 IILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMD 167
Query: 107 FETSPKSS--ALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVP 164
F+ T G+ + + R PC D P K ++ ++
Sbjct: 168 FQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRE 227
Query: 165 KELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALES----RQIGPRTL 220
+AL S + +T + E + + F V + YL+A +V S G +
Sbjct: 228 SRHIAL-SNMPKVKTIELEGGLLEDH-FETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVS 285
Query: 221 VWSEKEQVEKSAYEFSETESMLKIAEDLGGPYV-WGQYDLLVLPPSFPYGGMEN------ 273
+++ ++ ++ Y + +L E Y + DL+ +P P G MEN
Sbjct: 286 IYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAP-GAMENWGLITY 344
Query: 274 --PCLTFVTPTLLAGDKS-LSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHIC 330
L F T A DK ++ VIAHE++H W GNLVT + W+ WL EG Y+E
Sbjct: 345 RETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAV 404
Query: 331 GRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFAL 390
+ E L E+ + + P +K T I + V Y KG +
Sbjct: 405 NATYPELQFDDYFLNVCFEVITK-DSLNSSRPISKPAETPTQIQE--MFDEVSYNKGACI 461
Query: 391 LFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDD 424
L L+ LG + G ++ Y++KFSY++ DD
Sbjct: 462 LNMLKDFLGEEKFQKGIIQ-YLKKFSYRNAKNDD 494
>gi|11641261 endoplasmic reticulum aminopeptidase 2 [Homo sapiens]
Length = 960
Score = 81.6 bits (200), Expect = 2e-15
Identities = 91/394 (23%), Positives = 158/394 (40%), Gaps = 29/394 (7%)
Query: 53 LVLDTKDLTIEKVVINGQEVKYALGERQSYK------GSPMEISLPIALSKNQEIVIEIS 106
++L +KDL I + +E + + K + + +P L+ + + + +
Sbjct: 108 IILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMD 167
Query: 107 FETSPKSS--ALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVP 164
F+ T G+ + + R PC D P K ++ ++
Sbjct: 168 FQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRE 227
Query: 165 KELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALES----RQIGPRTL 220
+AL S + +T + E + + F V + YL+A +V S G +
Sbjct: 228 SRHIAL-SNMPKVKTIELEGGLLEDH-FETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVS 285
Query: 221 VWSEKEQVEKSAYEFSETESMLKIAEDLGGPYV-WGQYDLLVLPPSFPYGGMEN------ 273
+++ ++ ++ Y + +L E Y + DL+ +P P G MEN
Sbjct: 286 IYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAP-GAMENWGLITY 344
Query: 274 --PCLTFVTPTLLAGDKS-LSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHIC 330
L F T A DK ++ VIAHE++H W GNLVT + W+ WL EG Y+E
Sbjct: 345 RETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAV 404
Query: 331 GRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFAL 390
+ E L E+ + + P +K T I + V Y KG +
Sbjct: 405 NATYPELQFDDYFLNVCFEVITK-DSLNSSRPISKPAETPTQIQE--MFDEVSYNKGACI 461
Query: 391 LFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDD 424
L L+ LG + G ++ Y++KFSY++ DD
Sbjct: 462 LNMLKDFLGEEKFQKGIIQ-YLKKFSYRNAKNDD 494
>gi|24432058 aminopeptidase O [Homo sapiens]
Length = 720
Score = 48.5 bits (114), Expect = 2e-05
Identities = 56/248 (22%), Positives = 102/248 (41%), Gaps = 16/248 (6%)
Query: 373 IDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSY 432
++P+ + V Y KG+ LL +L + LG E + FL+ +V F + I + D+ L
Sbjct: 476 LNPEKIFMQVHYLKGYFLLRFLAKRLGD-ETYFSFLRKFVHTFHGQLILSQDFLQMLLEN 534
Query: 433 FKDKVDVLNQVD--WNAWLYSPGLP-PI----KPNYDMTLTNACIALSQRWITAKEDDLN 485
++ + V+ + WL S G+P P+ + + L A +WI
Sbjct: 535 IPEEKRLELSVENIYQDWLESSGIPKPLQRERRAGAECGLARQVRAEVTKWIGVNRRPRK 594
Query: 486 SFNATD---LKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRL 542
+ L QL L L++ L ++ +Q Y+ ++E+R RW L
Sbjct: 595 RKRREKEEVFEKLLPDQLVLLLEHLLEQKTLSPRTLQSLQRTYHLQD-QDAEVRHRWCEL 653
Query: 543 CIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQ--AVRTYQEHKASMHPVT 600
++ K+ A + E M L+ +L + + Q A R ++ K M +
Sbjct: 654 IVKHKFTKAYKSVERFLQEDQAMGVY--LYGELMVSEDARQQQLARRCFERTKEQMDRSS 711
Query: 601 AMLVGKDL 608
A +V + L
Sbjct: 712 AQVVAEML 719
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/135 (22%), Positives = 58/135 (42%), Gaps = 9/135 (6%)
Query: 103 IEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVS 162
I I ++T P+ ++ W + + SG+ P +++ I+ RA+ PCQ+ P T+ A V
Sbjct: 244 IRIWYKTKPEGRSVTWTSDQ--SGR--PCVYTVGSPINNRALFPCQEPPVAMSTWQATVR 299
Query: 163 VPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVW 222
V LMS + + Y ++ +P+P + VG ++ W
Sbjct: 300 AAASFVVLMSGENSAKPTQLWEECSSWYYYV-TMPMPASTFTIAVGCWTEMKME----TW 354
Query: 223 SEKEQVEKSAYEFSE 237
S + + + SE
Sbjct: 355 SSNDLATERPFSPSE 369
>gi|14196471 protocadherin gamma subfamily A, 5 isoform 2 precursor
[Homo sapiens]
Length = 813
Score = 31.6 bits (70), Expect = 2.2
Identities = 17/64 (26%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Query: 151 PSVKLTYTAEVSVPKELVALMSAIRDGETP-DPEDPSRKIYKFIQKVPIPCYLIALVVGA 209
P + T+T V+V + +++ + +TP DPED +Y + + C +A V+
Sbjct: 652 PPLSATFTVTVAVADRIPDILADLGSIKTPIDPEDLDLTLYLVVAVAAVSCVFLAFVIVL 711
Query: 210 LESR 213
L R
Sbjct: 712 LVLR 715
>gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 31.6 bits (70), Expect = 2.2
Identities = 17/64 (26%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Query: 151 PSVKLTYTAEVSVPKELVALMSAIRDGETP-DPEDPSRKIYKFIQKVPIPCYLIALVVGA 209
P + T+T V+V + +++ + +TP DPED +Y + + C +A V+
Sbjct: 652 PPLSATFTVTVAVADRIPDILADLGSIKTPIDPEDLDLTLYLVVAVAAVSCVFLAFVIVL 711
Query: 210 LESR 213
L R
Sbjct: 712 LVLR 715
>gi|194097462 actin-like 9 [Homo sapiens]
Length = 416
Score = 30.8 bits (68), Expect = 3.8
Identities = 15/32 (46%), Positives = 21/32 (65%)
Query: 485 NSFNATDLKDLSSHQLNEFLAQTLQRAPLPLG 516
N +AT+ DL+ + L FLA+ L +A LPLG
Sbjct: 213 NLLHATERLDLAGNHLTAFLAEMLLQAGLPLG 244
>gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]
Length = 4158
Score = 30.4 bits (67), Expect = 5.0
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 3/83 (3%)
Query: 45 SQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLP---IALSKNQEI 101
S+ D L+ L +K ++ V+NGQ KYA Q KG P +P + K +E
Sbjct: 897 SEWDKLQQEWLKSKFDCLDPEVLNGQVSKYAKFVTQLEKGLPPNSVVPQLKYKVEKMKEK 956
Query: 102 VIEISFETSPKSSALQWLTPEQT 124
+ I +P A W EQT
Sbjct: 957 LPVIIDLRNPTLKARHWAAIEQT 979
>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo
sapiens]
Length = 1015
Score = 29.6 bits (65), Expect = 8.5
Identities = 17/76 (22%), Positives = 36/76 (47%)
Query: 183 EDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESML 242
EDP++ +++F +++ C I V+GA E ++ L K ++ + +
Sbjct: 635 EDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEK 694
Query: 243 KIAEDLGGPYVWGQYD 258
+ + LG + GQ+D
Sbjct: 695 QRRDFLGEASIMGQFD 710
>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo
sapiens]
Length = 1037
Score = 29.6 bits (65), Expect = 8.5
Identities = 17/76 (22%), Positives = 36/76 (47%)
Query: 183 EDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESML 242
EDP++ +++F +++ C I V+GA E ++ L K ++ + +
Sbjct: 657 EDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEK 716
Query: 243 KIAEDLGGPYVWGQYD 258
+ + LG + GQ+D
Sbjct: 717 QRRDFLGEASIMGQFD 732
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,909,341
Number of Sequences: 37866
Number of extensions: 1056238
Number of successful extensions: 2557
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2504
Number of HSP's gapped (non-prelim): 29
length of query: 611
length of database: 18,247,518
effective HSP length: 108
effective length of query: 503
effective length of database: 14,157,990
effective search space: 7121468970
effective search space used: 7121468970
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.