BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] (1048 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] 2117 0.0 gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] 2019 0.0 gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] 1992 0.0 gi|49170034 integrin, alpha 8 [Homo sapiens] 970 0.0 gi|56237029 integrin alpha 5 precursor [Homo sapiens] 922 0.0 gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] 630 e-180 gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [... 335 2e-91 gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [... 333 4e-91 gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] 319 1e-86 gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] 314 3e-85 gi|67191027 integrin alpha 4 precursor [Homo sapiens] 296 9e-80 gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] 276 6e-74 gi|52485941 integrin, alpha 9 precursor [Homo sapiens] 270 5e-72 gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] 270 5e-72 gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] 267 3e-71 gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 211 3e-54 gi|116295258 integrin alpha 2 precursor [Homo sapiens] 199 9e-51 gi|52485853 integrin, alpha 11 precursor [Homo sapiens] 171 3e-42 gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 168 2e-41 gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 167 6e-41 gi|34452173 integrin alpha X precursor [Homo sapiens] 167 6e-41 gi|148728188 integrin, alpha E precursor [Homo sapiens] 159 1e-38 gi|38569398 integrin, alpha 10 precursor [Homo sapiens] 149 1e-35 gi|62548866 integrin, alpha D precursor [Homo sapiens] 147 7e-35 gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] 123 1e-27 gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] 121 3e-27 gi|29171717 glycosylphosphatidylinositol specific phospholipase ... 62 4e-09 gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ... 50 9e-06 gi|31881770 ADAM metallopeptidase domain 30 preproprotein [Homo ... 32 4.1 gi|8393638 F11 receptor precursor [Homo sapiens] 31 5.3 >gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] Length = 1048 Score = 2117 bits (5484), Expect = 0.0 Identities = 1048/1048 (100%), Positives = 1048/1048 (100%) Query: 1 MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSA 60 MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSA Sbjct: 1 MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSA 60 Query: 61 SSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKS 120 SSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKS Sbjct: 61 SSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKS 120 Query: 121 HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDAD 180 HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDAD Sbjct: 121 HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDAD 180 Query: 181 GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLAT 240 GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLAT Sbjct: 181 GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLAT 240 Query: 241 RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE 300 RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE Sbjct: 241 RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE 300 Query: 301 QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK 360 QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK Sbjct: 301 QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK 360 Query: 361 LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQI 420 LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQI Sbjct: 361 LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQI 420 Query: 421 LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY 480 LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY Sbjct: 421 LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY 480 Query: 481 PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRR 540 PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRR Sbjct: 481 PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRR 540 Query: 541 ALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAAD 600 ALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAAD Sbjct: 541 ALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAAD 600 Query: 601 TTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVK 660 TTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVK Sbjct: 601 TTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVK 660 Query: 661 AQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAG 720 AQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAG Sbjct: 661 AQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAG 720 Query: 721 TQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSP 780 TQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSP Sbjct: 721 TQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSP 780 Query: 781 DHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLY 840 DHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLY Sbjct: 781 DHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLY 840 Query: 841 ILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIH 900 ILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIH Sbjct: 841 ILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIH 900 Query: 901 TLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIE 960 TLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIE Sbjct: 901 TLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIE 960 Query: 961 FPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGF 1020 FPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGF Sbjct: 961 FPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGF 1020 Query: 1021 FKRVRPPQEEQEREQLQPHENGEGNSET 1048 FKRVRPPQEEQEREQLQPHENGEGNSET Sbjct: 1021 FKRVRPPQEEQEREQLQPHENGEGNSET 1048 >gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] Length = 1012 Score = 2019 bits (5231), Expect = 0.0 Identities = 1011/1048 (96%), Positives = 1012/1048 (96%), Gaps = 36/1048 (3%) Query: 1 MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSA 60 MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSA Sbjct: 1 MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSA 60 Query: 61 SSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKS 120 SSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKS Sbjct: 61 SSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKS 120 Query: 121 HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDAD 180 HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRS+ Sbjct: 121 HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSR----- 175 Query: 181 GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLAT 240 QLISDQVAEIVSKYDPNVYSIKYNNQLAT Sbjct: 176 -------------------------------QLISDQVAEIVSKYDPNVYSIKYNNQLAT 204 Query: 241 RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE 300 RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE Sbjct: 205 RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE 264 Query: 301 QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK 360 QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK Sbjct: 265 QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK 324 Query: 361 LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQI 420 LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQI Sbjct: 325 LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQI 384 Query: 421 LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY 480 LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY Sbjct: 385 LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY 444 Query: 481 PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRR 540 PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRR Sbjct: 445 PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRR 504 Query: 541 ALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAAD 600 ALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAAD Sbjct: 505 ALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAAD 564 Query: 601 TTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVK 660 TTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVK Sbjct: 565 TTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVK 624 Query: 661 AQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAG 720 AQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAG Sbjct: 625 AQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAG 684 Query: 721 TQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSP 780 TQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSP Sbjct: 685 TQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSP 744 Query: 781 DHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLY 840 DHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLY Sbjct: 745 DHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLY 804 Query: 841 ILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIH 900 ILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIH Sbjct: 805 ILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIH 864 Query: 901 TLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIE 960 TLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIE Sbjct: 865 TLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIE 924 Query: 961 FPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGF 1020 FPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGF Sbjct: 925 FPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGF 984 Query: 1021 FKRVRPPQEEQEREQLQPHENGEGNSET 1048 FKRVRPPQEEQEREQLQPHENGEGNSET Sbjct: 985 FKRVRPPQEEQEREQLQPHENGEGNSET 1012 >gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] Length = 1002 Score = 1992 bits (5160), Expect = 0.0 Identities = 986/986 (100%), Positives = 986/986 (100%) Query: 63 RMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQ 122 RMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQ Sbjct: 17 RMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQ 76 Query: 123 WFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQ 182 WFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQ Sbjct: 77 WFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQ 136 Query: 183 GFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRT 242 GFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRT Sbjct: 137 GFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRT 196 Query: 243 AQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQM 302 AQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQM Sbjct: 197 AQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQM 256 Query: 303 AAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLN 362 AAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLN Sbjct: 257 AAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLN 316 Query: 363 GFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILE 422 GFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILE Sbjct: 317 GFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILE 376 Query: 423 GQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPS 482 GQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPS Sbjct: 377 GQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPS 436 Query: 483 ILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRAL 542 ILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRAL Sbjct: 437 ILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRAL 496 Query: 543 FLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTT 602 FLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTT Sbjct: 497 FLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTT 556 Query: 603 GLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQ 662 GLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQ Sbjct: 557 GLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQ 616 Query: 663 NQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQ 722 NQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQ Sbjct: 617 NQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQ 676 Query: 723 LLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDH 782 LLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDH Sbjct: 677 LLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDH 736 Query: 783 IFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYIL 842 IFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYIL Sbjct: 737 IFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYIL 796 Query: 843 HYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTL 902 HYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTL Sbjct: 797 HYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTL 856 Query: 903 GCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFP 962 GCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFP Sbjct: 857 GCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFP 916 Query: 963 YKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFK 1022 YKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFK Sbjct: 917 YKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFK 976 Query: 1023 RVRPPQEEQEREQLQPHENGEGNSET 1048 RVRPPQEEQEREQLQPHENGEGNSET Sbjct: 977 RVRPPQEEQEREQLQPHENGEGNSET 1002 >gi|49170034 integrin, alpha 8 [Homo sapiens] Length = 1063 Score = 970 bits (2507), Expect = 0.0 Identities = 500/1052 (47%), Positives = 691/1052 (65%), Gaps = 31/1052 (2%) Query: 12 GPRG--LPLLLS--------GLLL--PLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPS 59 GPRG PL+ G+LL P C+AFNLDV+ YSGP+GSYFG+AVDF +P Sbjct: 8 GPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPD 67 Query: 60 ASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSS--TRRCQPIEFDATGNRDYAKD---D 114 A + +LVGAPKANT+QP IVEGG V C W + + +C+ I FD T NR + + Sbjct: 68 ARTAS-VLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGTKE 126 Query: 115 PLEFKSHQWFGASVRSKQDKILACAPLYHWRT-EMKQEREPVGTCF--LQDGTKTVEYAP 171 P+EFKS+QWFGA+V++ + K++ACAPLYHWRT + E++PVGTC+ +Q+ + E++P Sbjct: 127 PIEFKSNQWFGATVKAHKGKVVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSAYAEFSP 186 Query: 172 CRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYS 231 CR+ + D +GQG+CQ GFS+DF K +++GGPGSFYWQGQ+I+ VA+I++ Y Sbjct: 187 CRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDIL 246 Query: 232 IKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNM 291 K + T A A +DDSYLGYSVA G+F GD + V+G+PR A+ G V I + +M Sbjct: 247 RKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINSTDM 306 Query: 292 SSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQR 351 + + NFTGEQMA+YFG++V +D+N D DV +GAPLFM+R + +EVGQ+ + LQ Sbjct: 307 TFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQIYLYLQV 366 Query: 352 ASGDFQTTK-LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS 410 +S F+ + L G E F RFGSA+A LGDL+QDG+NDIAI P+ G+D++G V I+NG Sbjct: 367 SSLLFRDPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNK 426 Query: 411 TGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPV 470 GLN PSQ+L+G WA+ ++P FG++++G +DIDKN YPDLIVGAFG + +YRARPV Sbjct: 427 DGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPV 486 Query: 471 ITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD 530 +TV+A L ++P I+N +NKTC +P + +CF++R C G+ + + E+ LD Sbjct: 487 VTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIA-NTIVLMAEVQLD 545 Query: 531 KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFME 590 LKQKGAI+R LFL + + I R QC++ I YLRDE+EFRDKL+PI I + Sbjct: 546 SLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLN 605 Query: 591 YRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIG 650 Y LD T + ++PILN + +S QAHIL+DCGEDN+C P L++S D+ ++ IG Sbjct: 606 YSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKHQVIIG 665 Query: 651 DDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVV 710 D+N L LI+ A+N+GEGAYEAEL V IP +AD++G+ RNN+ LSC +K EN TR VV Sbjct: 666 DENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENVTRMVV 725 Query: 711 CDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLA 770 CDLGNPM +GT GLRF+V + + + S+ FDLQI+SSN + S VS ++++ +A Sbjct: 726 CDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQINITAVA 785 Query: 771 AVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWP 830 VEIRGVS P I LPI NWE +E P EE+VGP+V+HIYEL N GPS+ S +L + WP Sbjct: 786 QVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTILEVGWP 845 Query: 831 YKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIK-ISSLQTTEKNDTVAGQGERDHLITK 889 + + LLYI H GP+ C + INP IK +S + T + HL+ K Sbjct: 846 FSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRK 905 Query: 890 RDLALSE----GDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQN 945 RD+ + E L C +CL+I C VGRL+ G+SA+L V+S LW TF+ ++N Sbjct: 906 RDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKND- 964 Query: 946 HSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGL 1005 Y+L S SF V + PY + P + S + T+V W +P+WVIILA+L GL Sbjct: 965 -PYALASLVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLWVIILAILLGL 1023 Query: 1006 LLLAVLVFVMYRMGFFKRVRPPQEEQ-EREQL 1036 L+LA+L +++ GFF R RPPQE+ +REQL Sbjct: 1024 LVLAILTLALWKCGFFDRARPPQEDMTDREQL 1055 >gi|56237029 integrin alpha 5 precursor [Homo sapiens] Length = 1049 Score = 922 bits (2383), Expect = 0.0 Identities = 485/1049 (46%), Positives = 676/1049 (64%), Gaps = 37/1049 (3%) Query: 8 RLRLGPRGLPLLLSGLLL-----PLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASS 62 +LR GPR P LL LLL P FNLD ++PA SGP GS+FGF+V+F+ P Sbjct: 14 QLRWGPRRRPPLLPLLLLLLPPPPRVGGFNLDAEAPAVLSGPPGSFFGFSVEFYRPGTDG 73 Query: 63 RMFLLVGAPKANTTQPGIVEGGQVLKCDW-SSTRRCQPIEFDATGNR-------DYAKDD 114 + +LVGAPKANT+QPG+++GG V C W +S +C PIEFD+ G+R ++ Sbjct: 74 -VSVLVGAPKANTSQPGVLQGGAVYLCPWGASPTQCTPIEFDSKGSRLLESSLSSSEGEE 132 Query: 115 PLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDG--TKTVEYAPC 172 P+E+KS QWFGA+VR+ ILACAPLY WRTE + +PVGTC+L T+ +EYAPC Sbjct: 133 PVEYKSLQWFGATVRAHGSSILACAPLYSWRTEKEPLSDPVGTCYLSTDNFTRILEYAPC 192 Query: 173 RSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSI 232 RS A GQG+CQGGFS +FTK RV+LGGPGS++WQGQ++S +I Y P Sbjct: 193 RSDFSWAAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQIAESYYPEYLIN 252 Query: 233 KYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMS 292 QL TR A +I+DDSYLGYSVAVG+F+GD +DFV+GVP+ T G V I +G ++ Sbjct: 253 LVQGQLQTRQASSIYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVTILNGSDIR 312 Query: 293 SLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRA 352 SLYNF+GEQMA+YFG++VAATD+NGD D+ +GAPL MDR DG+ QEVG+V V LQ Sbjct: 313 SLYNFSGEQMASYFGYAVAATDVNGDGLDDLLVGAPLLMDRTPDGRPQEVGRVYVYLQHP 372 Query: 353 SG--DFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS 410 +G T L G + F RFGS++ PLGDLDQDG+ND+AI AP+GGE ++G+V++F G Sbjct: 373 AGIEPTPTLTLTGHDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFPGGP 432 Query: 411 TGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPV 470 GL + PSQ+L+ WAA P FG +++G D+D NGYPDLIVG+FGVD+A++YR RP+ Sbjct: 433 GGLGSKPSQVLQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRPI 492 Query: 471 ITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD 530 ++ +A L ++P++ N + ++CSL G V+C N+ FCL A GK V + F VEL LD Sbjct: 493 VSASASLTIFPAMFNPEERSCSLEGN--PVACINLSFCLNASGKHVAD-SIGFTVELQLD 549 Query: 531 KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFME 590 KQKG +RRALFL SR + ++ + I G C E+ YLR+ESEFRDKL+PI I + Sbjct: 550 WQKQKGGVRRALFLASRQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHIALN 609 Query: 591 YRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIG 650 + LD + D+ GL+P L+ + + I +A ILLDCGEDN+C P L++ V +Q +Y+G Sbjct: 610 FSLDPQAPVDSHGLRPALHYQSKSRIEDKAQILLDCGEDNICVPDLQLEVFGEQNHVYLG 669 Query: 651 DDNPLTLIVKAQNQGE-GAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQV 709 D N L L AQN GE GAYEAEL V+ P +A++ G+VR+ + LSC + NQ+R + Sbjct: 670 DKNALNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGLVRHPGNFSSLSCDYFAVNQSRLL 729 Query: 710 VCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVL 769 VCDLGNPMKAG L GLRF+V + +++FD QI S NL + S VVS ++ + Sbjct: 730 VCDLGNPMKAGASLWGGLRFTVPHLRDTKKTIQFDFQILSKNLNNSQSDVVSFRLSVEAQ 789 Query: 770 AAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQW 829 A V + GVS P+ + P+ +W ++ P+ EED+GP V H+YEL N GPSS S+ +L L Sbjct: 790 AQVTLNGVSKPEAVLFPVSDWHPRDQPQKEEDLGPAVHHVYELINQGPSSISQGVLELSC 849 Query: 830 PYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITK 889 P LLY+ + G +NCT++ INP +++ + ++ Q +R+ Sbjct: 850 PQALEGQQLLYVTR--VTG-LNCTTNHPINPKGLEL------DPEGSLHHQQKRE--APS 898 Query: 890 RDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYS 949 R A S I L C A+C ++ C++G L + +S L + +W +TF+ +E+Q +S Sbjct: 899 RSSASSGPQI--LKCPEAECFRLRCELGPLHQQESQSLQLHFRVWAKTFLQREHQ--PFS 954 Query: 950 LKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLA 1009 L+ A + ++ PY+ LP + V T V W VP+W+IILA+L GLLLL Sbjct: 955 LQCEAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVPLWIIILAILFGLLLLG 1014 Query: 1010 VLVFVMYRMGFFKRVRPPQEEQEREQLQP 1038 +L++++Y++GFFKR P E+ QL+P Sbjct: 1015 LLIYILYKLGFFKRSLPYGTAMEKAQLKP 1043 >gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] Length = 1039 Score = 630 bits (1624), Expect = e-180 Identities = 399/1045 (38%), Positives = 569/1045 (54%), Gaps = 54/1045 (5%) Query: 18 LLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQ 77 LLL P A NLD Y+GP GS FGF++DF S R+ ++VGAP+ T Sbjct: 19 LLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDS-HGRVAIVVGAPR--TLG 75 Query: 78 PGIVEGGQVLKCDWSSTR-RCQPIEFDATGNRDYAKDDPLE-FKSHQWFGASVRSKQDKI 135 P E G V C W + +C + FD L+ FK+ Q GASV S D I Sbjct: 76 PSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVI 135 Query: 136 LACAPLYHWRTEMKQE---REPVGTCFLQ--DGTKTVEYAPCRSQDID--------ADGQ 182 +ACAP HW K E + PVG+CFL + + EY+PCR + + + Sbjct: 136 VACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDK 195 Query: 183 GFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQ-LATR 241 +C+ GFS T+A ++LG PG +Y+ G L VA+I S Y P + ++Q L+ Sbjct: 196 RYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFD 255 Query: 242 TAQAIFDDSYLGYSVAVGDFNGD-GIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE 300 ++ + D Y GYSVAVG+F+GD ++V G P + TLG V I D L+ GE Sbjct: 256 SSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSY-YQRLHRLRGE 314 Query: 301 QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQ----RASGDF 356 QMA+YFG SVA TD+NGD D+ +GAPL+M+ +D KL EVG+V + LQ A G Sbjct: 315 QMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGA- 373 Query: 357 QTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAV 416 + L G +++ RFGSAIAPLGDLD+DG+NDIA+AAPYGG +G V +F G+S GL + Sbjct: 374 PSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSR 433 Query: 417 PSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAG 476 PSQ+L+ + S +FG+S++GA DID NGYPDLIVGA+G ++ +YRA+PV+ + Sbjct: 434 PSQVLDSPFPTGS---AFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQ 490 Query: 477 LEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKG 536 L V S LN K+C LP T VSCFN++ C+ A G + P+KL+ EL LD+ K + Sbjct: 491 LLVQDS-LNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNI-PQKLSLNAELQLDRQKPRQ 548 Query: 537 AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYR 596 RR L L S+ + N+ + C +A+LRDE++FRDKL+PI + + L Sbjct: 549 G-RRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPT 607 Query: 597 TAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLT 656 A G+ P + ++ Q I+LDCGED+VC P+L+++ + +G DN L Sbjct: 608 EA----GMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLE 663 Query: 657 LIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNP 716 L + A N+GEGAYEAEL V +P A ++ + N E RL C K EN+TR V+C+LGNP Sbjct: 664 LQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNP 723 Query: 717 MKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRG 776 MK Q+ + SV E SV F LQI+S N + S +V V + A VE+RG Sbjct: 724 MKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRG 783 Query: 777 VSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNN 836 S P + + E ++N + + GP V+H YEL NNGP + + L + P + + Sbjct: 784 NSFPASLVVAAEEGEREQN--SLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPS 841 Query: 837 TLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSE 896 LLYIL G + C +NPL++ L + +RD +R + L E Sbjct: 842 DLLYILDIQPQGGLQCFPQPPVNPLKVD-WGLPIPSPSPIHPAHHKRD----RRQIFLPE 896 Query: 897 -------GDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYS 949 D + C A C + C + + RG+ A++ V + LW + + + Sbjct: 897 PEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLD--QFV 954 Query: 950 LKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLA 1009 L+S A FNV PY P+ V T + ++ +P+W +++ VL GLLLL Sbjct: 955 LQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALE--ERAIPIWWVLVGVLGGLLLLT 1012 Query: 1010 VLVFVMYRMGFFKRVRPPQEEQERE 1034 +LV M+++GFFKR RPP EE + E Sbjct: 1013 ILVLAMWKVGFFKRNRPPLEEDDEE 1037 >gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo sapiens] Length = 1091 Score = 335 bits (858), Expect = 2e-91 Identities = 303/1077 (28%), Positives = 508/1077 (47%), Gaps = 112/1077 (10%) Query: 19 LLSGLLLPLCRAFNLDV--DSPAEYSGPEGSYFGFAVDF-FVPSASSRMFLLVGAPKANT 75 L +GLL L AFNLD D+ G GS FGF++ + + LLVGAP+A Sbjct: 12 LSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEA 71 Query: 76 T--QPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQD 133 Q GG + CD ++ C IEFD D E K QW G +V+S+ Sbjct: 72 LPLQRANRTGG-LYSCDITARGPCTRIEFDNDA------DPTSESKEDQWMGVTVQSQGP 124 Query: 134 --KILACAPLYHWRTEM--KQE-REPVGTCF-------LQDGTKTVEYAPCRSQDIDADG 181 K++ CA Y R + KQE R+ G C+ ++D +++ C + + Sbjct: 125 GGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEK 184 Query: 182 QGFCQGGFSIDFTKADR-VLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSI-KYNNQLA 239 G CQ G + FTK ++ G PG++ W+G + +Q +D N++ Y Sbjct: 185 FGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTF--FDMNIFEDGPYEVGGE 242 Query: 240 TRTAQAIFD---DSYLGYSVAVGD--FNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSL 294 T +++ +SYLG+S+ G + D I FVSG PRA + +V + + L Sbjct: 243 TEHDESLVPVPANSYLGFSLDSGKGIVSKDEIT-FVSGAPRANHSGAVVLLKRDMKSAHL 301 Query: 295 ---YNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQR 351 + F GE +A+ FG+ VA D+N D + D+ IGAP + DR DG++ V ++ Q Sbjct: 302 LPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDR--DGEVGGAVYVYMNQQG 359 Query: 352 ASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRST 411 + + +LNG + + FG A+ +GD++QDG+ DIA+ APY D G V+I++G + Sbjct: 360 RWNNVKPIRLNGTKD-SMFGIAVKNIGDINQDGYPDIAVGAPY---DDLGKVFIYHGSAN 415 Query: 412 GLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVI 471 G+N P+Q+L+G + P FGYS+ G D+D+N YPD+ VG+ D ++R+RPVI Sbjct: 416 GINTKPTQVLKG------ISPYFGYSIAGNMDLDRNSYPDVAVGSLS-DSVTIFRSRPVI 468 Query: 472 TVNAGLEVYPSILNQDNKT-CSLPGTALKVSCFNVRFCLK--ADGKGVLPRKLNFQVELL 528 + + V P+ ++ KT C P C V+ C + A+ G P ++ L Sbjct: 469 NIQKTITVTPNRIDLRQKTACGAPSGI----CLQVKSCFEYTANPAGYNP-SISIVGTLE 523 Query: 529 LDKLKQK-GAIRRALFLYSRS-PSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPIT 586 +K ++K G R F S P +++ +T+ R C E +L+D RDKL PI Sbjct: 524 AEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDN--IRDKLRPIP 581 Query: 587 IFMEYRLDY----RTAADTTGLQPILNQFTPANISRQAHILLD-CGEDNVCKPKLEVSV- 640 I + R + PILN P H L + CG+DNVC L++ Sbjct: 582 ITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYK 641 Query: 641 ----DSDQKK------------IYIGDDNPLTLIVKAQNQ----------GEGAYEAELI 674 + +Q K + + D + L + N G+ A+EA+LI Sbjct: 642 FCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLI 701 Query: 675 VSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQ 734 + P + R A + Q C+LGNP K + + L S + Sbjct: 702 ATFPDTLTY-SAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEV 760 Query: 735 SEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKE 794 + + +L++++++ D ++P+ + K + + + + GV+ P ++ ++ Sbjct: 761 TFDTPDLDINLKLETTSNQDNLAPITA-KAKVVIELLLSVSGVAKPSQVYFG-GTVVGEQ 818 Query: 795 NPETEEDVGPVVQHIYELRNNGP--SSFSKAMLHLQWPYKYNNNT-LLYILHYDIDG--P 849 ++E++VG ++++ + + N G ++ A L++QWP + +N LLY++ + G Sbjct: 819 AMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEK 878 Query: 850 MNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGV-AQ 908 + C EIN L + S ++ T E+ ++ +E TL C V Sbjct: 879 VTCEPQKEINSLNLTESHNSRKKREIT-----EKQIDDNRKFSLFAERKYQTLNCSVNVN 933 Query: 909 CLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPI 968 C+ I C + LD S IL +S LW TF+ + ++ + + A +V +N+ + Sbjct: 934 CVNIRCPLRGLDSKASLIL--RSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAA-ENIRL 990 Query: 969 EDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVR 1025 + VT + + VP W+I++A+LAG+L+LA+LVF++++ GFFKR R Sbjct: 991 PNAGTQVRVTVFPSKTVAQYS-GVPWWIILVAILAGILMLALLVFILWKCGFFKRSR 1046 >gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo sapiens] Length = 1073 Score = 333 bits (855), Expect = 4e-91 Identities = 302/1075 (28%), Positives = 507/1075 (47%), Gaps = 112/1075 (10%) Query: 19 LLSGLLLPLCRAFNLDV--DSPAEYSGPEGSYFGFAVDF-FVPSASSRMFLLVGAPKANT 75 L +GLL L AFNLD D+ G GS FGF++ + + LLVGAP+A Sbjct: 12 LSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEA 71 Query: 76 T--QPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQD 133 Q GG + CD ++ C IEFD D E K QW G +V+S+ Sbjct: 72 LPLQRANRTGG-LYSCDITARGPCTRIEFDNDA------DPTSESKEDQWMGVTVQSQGP 124 Query: 134 --KILACAPLYHWRTEM--KQE-REPVGTCF-------LQDGTKTVEYAPCRSQDIDADG 181 K++ CA Y R + KQE R+ G C+ ++D +++ C + + Sbjct: 125 GGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEK 184 Query: 182 QGFCQGGFSIDFTKADR-VLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSI-KYNNQLA 239 G CQ G + FTK ++ G PG++ W+G + +Q +D N++ Y Sbjct: 185 FGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTF--FDMNIFEDGPYEVGGE 242 Query: 240 TRTAQAIFD---DSYLGYSVAVGD--FNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSL 294 T +++ +SYLG+S+ G + D I FVSG PRA + +V + + L Sbjct: 243 TEHDESLVPVPANSYLGFSLDSGKGIVSKDEIT-FVSGAPRANHSGAVVLLKRDMKSAHL 301 Query: 295 ---YNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQR 351 + F GE +A+ FG+ VA D+N D + D+ IGAP + DR DG++ V ++ Q Sbjct: 302 LPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDR--DGEVGGAVYVYMNQQG 359 Query: 352 ASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRST 411 + + +LNG + + FG A+ +GD++QDG+ DIA+ APY D G V+I++G + Sbjct: 360 RWNNVKPIRLNGTKD-SMFGIAVKNIGDINQDGYPDIAVGAPY---DDLGKVFIYHGSAN 415 Query: 412 GLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVI 471 G+N P+Q+L+G + P FGYS+ G D+D+N YPD+ VG+ D ++R+RPVI Sbjct: 416 GINTKPTQVLKG------ISPYFGYSIAGNMDLDRNSYPDVAVGSLS-DSVTIFRSRPVI 468 Query: 472 TVNAGLEVYPSILNQDNKT-CSLPGTALKVSCFNVRFCLK--ADGKGVLPRKLNFQVELL 528 + + V P+ ++ KT C P C V+ C + A+ G P ++ L Sbjct: 469 NIQKTITVTPNRIDLRQKTACGAPSGI----CLQVKSCFEYTANPAGYNP-SISIVGTLE 523 Query: 529 LDKLKQK-GAIRRALFLYSRS-PSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPIT 586 +K ++K G R F S P +++ +T+ R C E +L+D RDKL PI Sbjct: 524 AEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDN--IRDKLRPIP 581 Query: 587 IFMEYRLDY----RTAADTTGLQPILNQFTPANISRQAHILLD-CGEDNVCKPKLEVSV- 640 I + R + PILN P H L + CG+DNVC L++ Sbjct: 582 ITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYK 641 Query: 641 ----DSDQKK------------IYIGDDNPLTLIVKAQNQ----------GEGAYEAELI 674 + +Q K + + D + L + N G+ A+EA+LI Sbjct: 642 FCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLI 701 Query: 675 VSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQ 734 + P + R A + Q C+LGNP K + + L S + Sbjct: 702 ATFPDTLTY-SAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEV 760 Query: 735 SEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKE 794 + + +L++++++ D ++P+ + K + + + + GV+ P ++ ++ Sbjct: 761 TFDTPDLDINLKLETTSNQDNLAPITA-KAKVVIELLLSVSGVAKPSQVYFG-GTVVGEQ 818 Query: 795 NPETEEDVGPVVQHIYELRNNGP--SSFSKAMLHLQWPYKYNNNT-LLYILHYDIDG--P 849 ++E++VG ++++ + + N G ++ A L++QWP + +N LLY++ + G Sbjct: 819 AMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEK 878 Query: 850 MNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGV-AQ 908 + C EIN L + S ++ T E+ ++ +E TL C V Sbjct: 879 VTCEPQKEINSLNLTESHNSRKKREIT-----EKQIDDNRKFSLFAERKYQTLNCSVNVN 933 Query: 909 CLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPI 968 C+ I C + LD S IL +S LW TF+ + ++ + + A +V +N+ + Sbjct: 934 CVNIRCPLRGLDSKASLIL--RSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAA-ENIRL 990 Query: 969 EDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKR 1023 + VT + + VP W+I++A+LAG+L+LA+LVF++++ GFFKR Sbjct: 991 PNAGTQVRVTVFPSKTVAQYS-GVPWWIILVAILAGILMLALLVFILWKCGFFKR 1044 >gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] Length = 1137 Score = 319 bits (817), Expect = 1e-86 Identities = 322/1116 (28%), Positives = 509/1116 (45%), Gaps = 141/1116 (12%) Query: 6 RRRLRLGPRGLPLLLSGLLLPL----CRAFNLDVDSPAEYSGPEGSYFGFAVDFFVP-SA 60 R R G G+ L LL+ L AFNLDV G GS FGF+V Sbjct: 5 RSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQP 64 Query: 61 SSRMFLLVGAPKANTTQPGIVEG--GQVLKCDWSSTRR-CQPIEFDATGNRDYAKDDPLE 117 + +LLVGAP+A PG G + C S C ++ D D E Sbjct: 65 RPQSWLLVGAPQA-LALPGQQANRTGGLFACPLSLEETDCYRVDIDQ------GADMQKE 117 Query: 118 FKSHQWFGASVRSKQD--KILACAPLYHWRTEMKQ---EREPVGTCF-------LQDGTK 165 K +QW G SVRS+ KI+ CA Y R + Q R+ +G CF ++D Sbjct: 118 SKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELD 177 Query: 166 TVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLL-GGPGSFYWQGQLISDQVAEIVSK 224 E+ C + + GFCQ G + F+ LL G PG++ W+G L + S Sbjct: 178 GGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDS--SD 235 Query: 225 YDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGID-----DFVSGVPRAART 279 D VY A + +SYLG+S+ +G G+ FV+G PRA Sbjct: 236 PDQLVYKTLDPADRLPGPAGDLALNSYLGFSID----SGKGLVRAEELSFVAGAPRANHK 291 Query: 280 LGMVYIYDGKNMSSLYN---FTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSD 336 G V I + S L +GE++ + FG+S+A D+N D + D+ +GAP F +R + Sbjct: 292 -GAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEE 350 Query: 337 GKLQEVGQVSVSLQRAS--GDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPY 394 G V V L + +L G + FG ++A LGDL+QDGF DIA+ AP+ Sbjct: 351 LG----GAVYVYLNQGGHWAGISPLRLCG-SPDSMFGISLAVLGDLNQDGFPDIAVGAPF 405 Query: 395 GGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIV 454 G+ K V+I++G S G+ A PSQ+LEG+ SFGYS+ G+ D+D N YPDL+V Sbjct: 406 DGDGK---VFIYHGSSLGVVAKPSQVLEGEAVGIK---SFGYSLSGSLDMDGNQYPDLLV 459 Query: 455 GAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLK--AD 512 G+ D A+L+RARP++ V+ + + P ++ + C+ + C ++R C A Sbjct: 460 GSL-ADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSV----CVDLRVCFSYIAV 514 Query: 513 GKGVLPR-KLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELI-- 569 P L++ ++ D+ + +G + R FL SR+ K+ L + + Sbjct: 515 PSSYSPTVALDYVLDADTDR-RLRGQVPRVTFL-SRNLEEPKHQASGTVWLKHQHDRVCG 572 Query: 570 -AYLRDESEFRDKLTPITIFMEYRLD---YRTAADTTGL---QPILNQFTPANISRQAHI 622 A + + +DKL I + + Y L R A GL PILN P+ + H Sbjct: 573 DAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHF 632 Query: 623 LLD-CGEDNVCKPKLEV--------SVDSDQKKIYIGDDNPLTLI--------------- 658 L CGED +C+ L++ D++ + + + D L Sbjct: 633 LKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVT 692 Query: 659 ------VKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCD 712 + Q G+ A+EA+L+V +P + GV + A L EN + V C+ Sbjct: 693 NLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPL--CLSNENAS-HVECE 749 Query: 713 LGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAV 772 LGNPMK G Q+ L S S T ++ +L + + + ++ VS + + + + Sbjct: 750 LGNPMKRGAQVTFYLILSTSGISIETTELEVELLL--ATISEQELHPVSARARVFIELPL 807 Query: 773 EIRGVSSPDHIFLP-IPNWEHKENPETEEDVGPVVQHIYELRNNGPS--SFSKAMLHLQW 829 I G++ P +F + E ++E DVG V++ + N G S + A L++ W Sbjct: 808 SIAGMAIPQQLFFSGVVRGERA--MQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMW 865 Query: 830 PYKY-NNNTLLYILHYDIDG-----------PMNCTSDMEINPLRIKISSLQTTEKNDTV 877 P++ N LLY + +++G P ++++ + L+ E+ + Sbjct: 866 PHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQE-- 923 Query: 878 AGQGERDHLITKRDLALSEGDIHTLGC--GVAQCLKIVCQVGRLDRGKSAILYVKSLLWT 935 G+ + + + + TL C G A C+ C + DR +A+L+V LW Sbjct: 924 PGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDR--AAVLHVWGRLWN 981 Query: 936 ETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPM---PV 992 TF+ + + S + A+ V + KNL + D ST++ V + P + V Sbjct: 982 STFLEEYSAVKSLEVIVRANITV-KSSIKNLMLRDA--STVIPVMVY--LDPMAVVAEGV 1036 Query: 993 PVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQ 1028 P WVI+LAVLAGLL+LA+LV ++++MGFFKR + P+ Sbjct: 1037 PWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPE 1072 >gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] Length = 1141 Score = 314 bits (804), Expect = 3e-85 Identities = 319/1119 (28%), Positives = 510/1119 (45%), Gaps = 143/1119 (12%) Query: 6 RRRLRLGPRGLPLLLSGLLLPL----CRAFNLDVDSPAEYSGPEGSYFGFAVDFFVP-SA 60 R R G G+ L LL+ L AFNLDV G GS FGF+V Sbjct: 5 RSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQP 64 Query: 61 SSRMFLLVGAPKANTTQPGIVEG--GQVLKCDWSSTRR-CQPIEFDATGNRDYAKDDPLE 117 + +LLVGAP+A PG G + C S C ++ D D E Sbjct: 65 RPQSWLLVGAPQA-LALPGQQANRTGGLFACPLSLEETDCYRVDIDQ------GADMQKE 117 Query: 118 FKSHQWFGASVRSKQD--KILACAPLYHWRTEMKQ---EREPVGTCF-------LQDGTK 165 K +QW G SVRS+ KI+ CA Y R + Q R+ +G CF ++D Sbjct: 118 SKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELD 177 Query: 166 TVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLL-GGPGSFYWQGQL---ISDQVAEI 221 E+ C + + GFCQ G + F+ LL G PG++ W+G + Q + Sbjct: 178 GGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSAD 237 Query: 222 VSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGID-----DFVSGVPRA 276 ++ D Y + R + +SY G+S+ +G G+ FV+G PRA Sbjct: 238 LAHLDDGPYEAGGEKEQDPRLIP-VPANSYFGFSID----SGKGLVRAEELSFVAGAPRA 292 Query: 277 ARTLGMVYIYDGKNMSSLYN---FTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDR 333 G V I + S L +GE++ + FG+S+A D+N D + D+ +GAP F +R Sbjct: 293 NHK-GAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFER 351 Query: 334 GSDGKLQEVGQVSVSLQRAS--GDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIA 391 + G V V L + +L G + FG ++A LGDL+QDGF DIA+ Sbjct: 352 QEELG----GAVYVYLNQGGHWAGISPLRLCG-SPDSMFGISLAVLGDLNQDGFPDIAVG 406 Query: 392 APYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPD 451 AP+ G+ K V+I++G S G+ A PSQ+LEG+ SFGYS+ G+ D+D N YPD Sbjct: 407 APFDGDGK---VFIYHGSSLGVVAKPSQVLEGEAVGIK---SFGYSLSGSLDMDGNQYPD 460 Query: 452 LIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLK- 510 L+VG+ D A+L+RARP++ V+ + + P ++ + C+ + C ++R C Sbjct: 461 LLVGSL-ADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSV----CVDLRVCFSY 515 Query: 511 -ADGKGVLPR-KLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEEL 568 A P L++ ++ D+ + +G + R FL SR+ K+ L + Sbjct: 516 IAVPSSYSPTVALDYVLDADTDR-RLRGQVPRVTFL-SRNLEEPKHQASGTVWLKHQHDR 573 Query: 569 I---AYLRDESEFRDKLTPITIFMEYRLD---YRTAADTTGL---QPILNQFTPANISRQ 619 + A + + +DKL I + + Y L R A GL PILN P+ + Sbjct: 574 VCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAE 633 Query: 620 AHILLD-CGEDNVCKPKLEV--------SVDSDQKKIYIGDDNPLTLI------------ 658 H L CGED +C+ L++ D++ + + + D L Sbjct: 634 IHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLEL 693 Query: 659 ---------VKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQV 709 + Q G+ A+EA+L+V +P + GV + A L EN + V Sbjct: 694 MVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPL--CLSNENAS-HV 750 Query: 710 VCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVL 769 C+LGNPMK G Q+ L S S T ++ +L + + + ++ VS + + + Sbjct: 751 ECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLL--ATISEQELHPVSARARVFIE 808 Query: 770 AAVEIRGVSSPDHIFLP-IPNWEHKENPETEEDVGPVVQHIYELRNNGPS--SFSKAMLH 826 + I G++ P +F + E ++E DVG V++ + N G S + A L+ Sbjct: 809 LPLSIAGMAIPQQLFFSGVVRGERA--MQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLN 866 Query: 827 LQWPYKY-NNNTLLYILHYDIDG-----------PMNCTSDMEINPLRIKISSLQTTEKN 874 + WP++ N LLY + +++G P ++++ + L+ E+ Sbjct: 867 IMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQ 926 Query: 875 DTVAGQGERDHLITKRDLALSEGDIHTLGC--GVAQCLKIVCQVGRLDRGKSAILYVKSL 932 + G+ + + + + TL C G A C+ C + DR +A+L+V Sbjct: 927 E--PGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDR--AAVLHVWGR 982 Query: 933 LWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPM-- 990 LW TF+ + + S + A+ V + KNL + D ST++ V + P + Sbjct: 983 LWNSTFLEEYSAVKSLEVIVRANITV-KSSIKNLMLRDA--STVIPVMVY--LDPMAVVA 1037 Query: 991 -PVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQ 1028 VP WVI+LAVLAGLL+LA+LV ++++MGFFKR + P+ Sbjct: 1038 EGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPE 1076 >gi|67191027 integrin alpha 4 precursor [Homo sapiens] Length = 1032 Score = 296 bits (757), Expect = 9e-80 Identities = 294/1096 (26%), Positives = 485/1096 (44%), Gaps = 113/1096 (10%) Query: 1 MAFPPRRR---LRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFV 57 MA+ RR R R +LL L +P R +N+D +S Y GP + FG++V + Sbjct: 1 MAWEARREPGPRRAAVRETVMLLLCLGVPTGRPYNVDTESALLYQGPHNTLFGYSV--VL 58 Query: 58 PSASSRMFLLVGAPKAN-TTQPGIVEGGQVLKCDWSST--RRCQPIEFDATGNRDYAKDD 114 S + +LLVGAP AN ++ G + +C + C+ ++ + K Sbjct: 59 HSHGANRWLLVGAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTC 118 Query: 115 PLEFKSHQWFGASVR---SKQDKILACAPLYHWRT--EMKQERE-PVGTCFLQDGTKTVE 168 LE + +QW G ++ + I+ C + W+ +K E + P G C+ E Sbjct: 119 -LEERDNQWLGVTLSRQPGENGSIVTCG--HRWKNIFYIKNENKLPTGGCYGVPPDLRTE 175 Query: 169 Y----APCRSQDIDADGQGF--CQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIV 222 APC + G+ F CQ G S +TK D +++G PGS YW G L Sbjct: 176 LSKRIAPCYQDYVKKFGENFASCQAGISSFYTK-DLIVMGAPGSSYWTGSLF-------- 226 Query: 223 SKYDPNVYSIKYNNQLATRTAQ-AIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLG 281 VY+I N A Q + SYLGYSV G F + V G P+ + +G Sbjct: 227 ------VYNITTNKYKAFLDKQNQVKFGSYLGYSVGAGHFRSQHTTEVVGGAPQHEQ-IG 279 Query: 282 MVYIY--DGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKL 339 YI+ D K ++ L+ G+++ +YFG SV A D+N D ++D+ +GAP+ + Sbjct: 280 KAYIFSIDEKELNILHEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPM------QSTI 333 Query: 340 QEVGQVSVSLQRASG---DFQTTKLNGFEVFA-RFGSAIAPLGDLDQDGFNDIAIAAPYG 395 +E G+V V + SG + T L G + +A RFG +I LGD+D DGF D+AI AP Sbjct: 334 REEGRVFVYINSGSGAVMNAMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQE 393 Query: 396 GEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVG 455 +D +G +YI+NGR+ G+++ SQ +EG ++S+ FG S+ G D D NGY D+ VG Sbjct: 394 -DDLQGAIYIYNGRADGISSTFSQRIEGLQISKSLS-MFGQSISGQIDADNNGYVDVAVG 451 Query: 456 AFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKG 515 AF D A+L R RPV+ V+A L +P +N+ C G C ++ C GK Sbjct: 452 AFRSDSAVLLRTRPVVIVDASLS-HPESVNRTKFDCVENG--WPSVCIDLTLCFSYKGKE 508 Query: 516 VLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDE 575 V P + + LD ++ + R F + + C A++R Sbjct: 509 V-PGYIVLFYNMSLDVNRKAESPPRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMR-- 565 Query: 576 SEFRDKLTPITIFMEYRL-----DYRTAADTTGLQPILNQFTPANISRQA-HILLDCGED 629 + RD LTPI I Y L R+ + LQPIL Q +I ++ + C + Sbjct: 566 KDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHE 625 Query: 630 NVCKPKLEVS-----VDSDQKKIY--IGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQAD 682 N C L+VS + + K Y +G L L V N G+ AYE L V +P+ Sbjct: 626 N-CSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLY 684 Query: 683 FIGVVRNNEALARLSCAFKTENQTRQVVCDLGN---PMKAGTQLLAGLRFSVHQQSEMDT 739 FI ++ E +++C + Q+ C +G + + L S ++E D Sbjct: 685 FIKILELEE--KQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDL 742 Query: 740 SVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETE 799 S+ ++ D + +V +A+ E++ H F+ ++ + N E E Sbjct: 743 SITVHATCENEEEMDNLK---HSRVTVAIPLKYEVK---LTVHGFVNPTSFVYGSNDENE 796 Query: 800 EDVGPV--VQHIYELRNNGPSSFSKAMLHLQWPYKYNNNT--LLYILHYD-IDGPMNCTS 854 + V + + + N G S + + P ++ T L IL G + + Sbjct: 797 PETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLFNILDVQTTTGECHFEN 856 Query: 855 DMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVC 914 + L + S++QT + V + D KR L + D H CL +C Sbjct: 857 YQRVCALEQQKSAMQTLK--GIVRFLSKTD----KRLLYCIKADPH--------CLNFLC 902 Query: 915 QVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNS 974 G+++ GK A ++++ E + ++++ FP N + ++ Sbjct: 903 NFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATG------FPEPNPRVIELNKD 956 Query: 975 TLVTTNVTWGI--QPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKR-VRPPQEEQ 1031 V + G+ Q + +I ++L GL++L ++ +VM++ GFFKR + +E+ Sbjct: 957 ENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEE 1016 Query: 1032 EREQLQPHENGEGNSE 1047 R + N + N + Sbjct: 1017 NRRDSWSYINSKSNDD 1032 >gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] Length = 1044 Score = 276 bits (707), Expect = 6e-74 Identities = 272/977 (27%), Positives = 451/977 (46%), Gaps = 126/977 (12%) Query: 138 CAPLYHWRTEMKQ---EREPVGTCF-------LQDGTKTVEYAPCRSQDIDADGQGFCQG 187 CA Y R + Q R+ +G CF ++D E+ C + + GFCQ Sbjct: 43 CAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQ 102 Query: 188 GFSIDFTKADRVLL-GGPGSFYWQGQL---ISDQVAEIVSKYDPNVYSIKYNNQLATRTA 243 G + F+ LL G PG++ W+G + Q + ++ D Y + R Sbjct: 103 GTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLI 162 Query: 244 QAIFDDSYLGYSVAVGDFNGDGID-----DFVSGVPRAARTLGMVYIYDGKNMSSLYN-- 296 + +SY G+S+ +G G+ FV+G PRA G V I + S L Sbjct: 163 P-VPANSYFGFSID----SGKGLVRAEELSFVAGAPRANHK-GAVVILRKDSASRLVPEV 216 Query: 297 -FTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRAS-- 353 +GE++ + FG+S+A D+N D + D+ +GAP F +R + G V V L + Sbjct: 217 MLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELG----GAVYVYLNQGGHW 272 Query: 354 GDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGL 413 +L G + FG ++A LGDL+QDGF DIA+ AP+ G+ K V+I++G S G+ Sbjct: 273 AGISPLRLCG-SPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGK---VFIYHGSSLGV 328 Query: 414 NAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITV 473 A PSQ+LEG+ SFGYS+ G+ D+D N YPDL+VG+ D A+L+RARP++ V Sbjct: 329 VAKPSQVLEGEAVGIK---SFGYSLSGSLDMDGNQYPDLLVGSL-ADTAVLFRARPILHV 384 Query: 474 NAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLK--ADGKGVLPR-KLNFQVELLLD 530 + + + P ++ + C+ + C ++R C A P L++ ++ D Sbjct: 385 SHEVSIAPRSIDLEQPNCAGGHSV----CVDLRVCFSYIAVPSSYSPTVALDYVLDADTD 440 Query: 531 KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELI---AYLRDESEFRDKLTPITI 587 + + +G + R FL SR+ K+ L + + A + + +DKL I + Sbjct: 441 R-RLRGQVPRVTFL-SRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVV 498 Query: 588 FMEYRLD---YRTAADTTGL---QPILNQFTPANISRQAHILLD-CGEDNVCKPKLEV-- 638 + Y L R A GL PILN P+ + H L CGED +C+ L++ Sbjct: 499 TLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVR 558 Query: 639 ------SVDSDQKKIYIGDDNPLTLI---------------------VKAQNQGEGAYEA 671 D++ + + + D L + Q G+ A+EA Sbjct: 559 ARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEA 618 Query: 672 ELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSV 731 +L+V +P + GV + A L EN + V C+LGNPMK G Q+ L S Sbjct: 619 QLLVMLPDSLHYSGVRALDPAEKPL--CLSNENAS-HVECELGNPMKRGAQVTFYLILST 675 Query: 732 HQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLP-IPNW 790 S T ++ +L + + + ++ VS + + + + I G++ P +F + Sbjct: 676 SGISIETTELEVELLL--ATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRG 733 Query: 791 EHKENPETEEDVGPVVQHIYELRNNGPS--SFSKAMLHLQWPYKY-NNNTLLYILHYDID 847 E ++E DVG V++ + N G S + A L++ WP++ N LLY + +++ Sbjct: 734 ERA--MQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELE 791 Query: 848 G-----------PMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSE 896 G P ++++ + L+ E+ + G+ + + + + Sbjct: 792 GGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQE--PGERQEPSMSWWPVSSAEK 849 Query: 897 GDIHTLGC--GVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSA 954 TL C G A C+ C + DR +A+L+V LW TF+ + + S + A Sbjct: 850 KKNITLDCARGTANCVVFSCPLYSFDR--AAVLHVWGRLWNSTFLEEYSAVKSLEVIVRA 907 Query: 955 SFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPM---PVPVWVIILAVLAGLLLLAVL 1011 + V + KNL + D ST++ V + P + VP WVI+LAVLAGLL+LA+L Sbjct: 908 NITV-KSSIKNLMLRDA--STVIPVMVY--LDPMAVVAEGVPWWVILLAVLAGLLVLALL 962 Query: 1012 VFVMYRMGFFKRVRPPQ 1028 V ++++MGFFKR + P+ Sbjct: 963 VLLLWKMGFFKRAKHPE 979 >gi|52485941 integrin, alpha 9 precursor [Homo sapiens] Length = 1035 Score = 270 bits (690), Expect = 5e-72 Identities = 283/1101 (25%), Positives = 490/1101 (44%), Gaps = 137/1101 (12%) Query: 5 PRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRM 64 PR RL L L+++G+ A+NLD P + GP S+FG+AV + Sbjct: 7 PRGAGRLRALLLALVVAGIP---AGAYNLDPQRPVHFQGPADSFFGYAV--LEHFHDNTR 61 Query: 65 FLLVGAPKANTT-QPGIVEGGQVLKC--DWSSTRRCQPIEFDATGNRDYAKDDPL-EFKS 120 ++LVGAPKA++ P + G V KC + RRC ++ NR + E + Sbjct: 62 WVLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRD 121 Query: 121 HQWFGASV--RSKQD-KILACAPLYHWRTEMKQERE--PVGTCFLQDGT---KTVEYAPC 172 +W G S+ + K D ++LACA + W+ + P G C++ K PC Sbjct: 122 DEWMGVSLARQPKADGRVLACA--HRWKNIYYEADHILPHGFCYIIPSNLQAKGRTLIPC 179 Query: 173 RSQDIDADGQ--GFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVY 230 + G+ G CQ G + FT+ + V++G PGSFYW G + ++++ D N Y Sbjct: 180 YEEYKKKYGEEHGSCQAGIAGFFTE-ELVVMGAPGSFYWAGTI------KVLNLTD-NTY 231 Query: 231 SIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKN 290 +K N+++ +YLGY+V G F+ D V G P+ + +G VYI+ Sbjct: 232 -LKLNDEVIMNRRY-----TYLGYAVTAGHFSHPSTIDVVGGAPQD-KGIGKVYIFRADR 284 Query: 291 MSS----LYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVS 346 S ++ +G++M +YFG S+ A D+NGD +D+ +GAP+F + +++ GQV+ Sbjct: 285 RSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSE------IRDEGQVT 338 Query: 347 VSLQRASGDFQTT-KLNGFEVF-ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVY 404 V + R +G + L G + A FG +IA L DLD DGF D+AI AP +D G VY Sbjct: 339 VYINRGNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKE-DDFAGAVY 397 Query: 405 IFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAIL 464 I++G + G+ S L GQ + FG S+ G D+D NGYPD+ VGAF D +L Sbjct: 398 IYHGDAGGIVPQYSMKLSGQ-KINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVL 456 Query: 465 YRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQ 524 RARPVITV+ + P +N C V+C NV C GK V P ++ Sbjct: 457 LRARPVITVDVSI-FLPGSINITAPQCH--DGQQPVNCLNVTTCFSFHGKHV-PGEIGLN 512 Query: 525 VELLLD-KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQ-CEELIAYLRDESEFRDKL 582 L+ D K+KG + R F+ + + + C +A+++ +D + Sbjct: 513 YVLMADVAKKEKGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVK--RRVQDVI 570 Query: 583 TPITIFMEYRLDYRTAA----DTTGLQPILNQFTPANISRQAHILL-------DCGEDNV 631 +PI Y L + L P+L I+++ + DC D Sbjct: 571 SPIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSEDCAADLQ 630 Query: 632 CKPKLEVSVDSDQKKIY--IGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRN 689 + KL +S D+K +Y +G ++L + N G+ AY+A + ++ + FI + + Sbjct: 631 LQGKLLLS-SMDEKTLYLALGAVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQK 689 Query: 690 NEALARLSCAFKTENQTRQVVCDLGNP-MKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQ 748 E +SC + + C +G P M++ ++ + F S + + F + Q Sbjct: 690 EE--MGISCELLESDFLK---CSVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQ 744 Query: 749 SSN------LFDKVSPV---VSHKVDLAVLAAVE----IRGVSSPDHIFLPIPNWEHKEN 795 S N L D + + H+VD ++ + + G S F+ + + E Sbjct: 745 SGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQ 804 Query: 796 PETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNN-NTLLYILHYDIDGPMNCTS 854 P + ++ N GPS+ + + + +P + ++ ++ + + G Sbjct: 805 P---------INITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNC 855 Query: 855 DMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGC---GVAQCLK 911 + NP I E++++ ++ L C G++ CL Sbjct: 856 SFQKNPTPCIIPQ--------------EQENIFHTIFAFFTKSGRKVLDCEKPGIS-CLT 900 Query: 912 IVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSY----SLKSSASFNVIEFPYKNLP 967 C L + +S + + LL TE + + +K + V+E + N Sbjct: 901 AHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGN-- 958 Query: 968 IEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPP 1027 E++T V ++P V W+I +++L G+L+ +L ++++MGFF+R Sbjct: 959 PEEVT----VVFEALHNLEPRGYVVG-WIIAISLLVGILIFLLLAVLLWKMGFFRR---- 1009 Query: 1028 QEEQEREQLQPHENGEGNSET 1048 + +E ++ +N + N ++ Sbjct: 1010 ---RYKEIIEAEKNRKENEDS 1027 >gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] Length = 1051 Score = 270 bits (690), Expect = 5e-72 Identities = 301/1094 (27%), Positives = 474/1094 (43%), Gaps = 160/1094 (14%) Query: 13 PRGLPLLLSGLLLPLCR------AFNLDVDS-PAEYSGPEGSYFGFAVDFFVPSA-SSRM 64 PR L+L L L + AFNLD + +G GS FG++V + R Sbjct: 9 PRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRY 68 Query: 65 FLLVGAPKANTTQPGIVEG-GQVLKCDWSSTRRCQPIEFDATGNRDYAKDDP-LEFKSHQ 122 LL GAP+ G G V C ++ + D K+DP Sbjct: 69 LLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKD------DCERMNITVKNDPGHHIIEDM 122 Query: 123 WFGASVRSK--QDKILACAPLYH---WRTEMKQEREPVGTCFLQ---------DGTKTVE 168 W G +V S+ ++L CA Y W + + +R VG C+++ D +T Sbjct: 123 WLGVTVASQGPAGRVLVCAHRYTQVLW-SGSEDQRRMVGKCYVRGNDLELDSSDDWQTYH 181 Query: 169 YAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPN 228 C S + D G CQ G S FT+ + V G PG++ W+G Q E +D + Sbjct: 182 NEMCNS-NTDYLETGMCQLGTSGGFTQ-NTVYFGAPGAYNWKGNSYMIQRKE----WDLS 235 Query: 229 VYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDF--NGDGIDDFVSGVPRAARTLGMVYIY 286 YS K + Y+GY++ VG F + I V+G PR R +G V++ Sbjct: 236 EYSYKDPEDQG---------NLYIGYTMQVGSFILHPKNIT-IVTGAPRH-RHMGAVFLL 284 Query: 287 D---GKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVG 343 G ++ G Q+ AYFG ++A D+N D + D+ +GAP + +R K + G Sbjct: 285 SQEAGGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFER----KEEVGG 340 Query: 344 QVSVSLQRASGDFQ---TTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKK 400 + V + +A F + L+G A FG ++A +GD++QDGF DIA+ AP+ G K Sbjct: 341 AIYVFMNQAGTSFPAHPSLLLHGPSGSA-FGLSVASIGDINQDGFQDIAVGAPFEGLGK- 398 Query: 401 GIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVD 460 VYI++ S GL P Q++ G+ +FGYS+ G D+D+N YPDL+VG+ D Sbjct: 399 --VYIYHSSSKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLS-D 455 Query: 461 RAILYRARPVIT-VNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCL---KADGKGV 516 +L RARPVI V+ L P++L+ P SC V C ++ G Sbjct: 456 HIVLLRARPVINIVHKTLVPRPAVLD--------PALCTATSCVQVELCFAYNQSAGNPN 507 Query: 517 LPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDES 576 R + L D+ ++ +R F S S ++ M+C++L L D Sbjct: 508 YRRNITLAYTLEADRDRRPPRLR---FAGSESAVFHGFFSMPE---MRCQKLELLLMD-- 559 Query: 577 EFRDKLTPITIFMEYRLDYRTA-ADTTGLQ-----PILNQFTPANISRQAHILLDCGEDN 630 RDKL PI I M Y L R GL+ PILNQ + +CG DN Sbjct: 560 NLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPDN 619 Query: 631 VCKPKLEVS---VDSDQKKI----YIGDDNPLTLIVKAQN------QGEGAYEAELIVSI 677 C+ L++ V Q+K+ Y D L L + N GE A+EA L + + Sbjct: 620 KCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVV 679 Query: 678 PLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEM 737 P A + VR A N+T + C+LGNP K ++ + F V + Sbjct: 680 P-PALLLSSVRPPGAC--------QANET--IFCELGNPFKRNQRMELLIAFEVIGVTLH 728 Query: 738 DTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIR-GVSSPDHIFLPI--PNWEHKE 794 ++ LQ+ +S+ D + P++ L +L ++ +S +H + Sbjct: 729 TRDLQVQLQLSTSSHQDNLWPMI-----LTLLVDYTLQTSLSMVNHRLQSFFGGTVMGES 783 Query: 795 NPETEEDVGPVVQHIYEL--RNNGPSSFSKAMLHLQWPYKYNNNT-LLYILHYDIDG--- 848 +T EDVG +++ +++ G +L L+WPY+ +N LLY + G Sbjct: 784 GMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGS 843 Query: 849 -PMNCTSDMEINPLRIKISS--------LQTTEKNDTVAGQGERDHLITKRDLALSEGDI 899 P D+ INPL + +S + + D GQG + A SE + Sbjct: 844 WPCRPPGDL-INPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSE-TV 901 Query: 900 HTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVI 959 T G A C+ + C + D + VK+ +W TF+ + A+ Sbjct: 902 LTCATGRAHCVWLECPIP--DAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATL--- 956 Query: 960 EFPYKNLPIEDITNSTLVTTNVTWG--------IQPAPMPVPVWVIILAVLAGLLLLAVL 1011 F ++P ++ N T TW ++ P + +W++++AV AGLLLL ++ Sbjct: 957 -FLRTSIPTINMENKT------TWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLI 1009 Query: 1012 VFVMYRMGFFKRVR 1025 + ++++ GFFKR R Sbjct: 1010 ILLLWKCGFFKRAR 1023 >gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] Length = 1066 Score = 267 bits (683), Expect = 3e-71 Identities = 300/1094 (27%), Positives = 473/1094 (43%), Gaps = 160/1094 (14%) Query: 13 PRGLPLLLSGLLLPLCR------AFNLDVDS-PAEYSGPEGSYFGFAVDFFVPSA-SSRM 64 PR L+L L L + AFNLD + +G GS FG++V + R Sbjct: 9 PRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRY 68 Query: 65 FLLVGAPKANTTQPGIVEG-GQVLKCDWSSTRRCQPIEFDATGNRDYAKDDP-LEFKSHQ 122 LL GAP+ G G V C ++ + D K+DP Sbjct: 69 LLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKD------DCERMNITVKNDPGHHIIEDM 122 Query: 123 WFGASVRSK--QDKILACAPLYH---WRTEMKQEREPVGTCFLQ---------DGTKTVE 168 W G +V S+ ++L CA Y W + + +R VG C+++ D +T Sbjct: 123 WLGVTVASQGPAGRVLVCAHRYTQVLW-SGSEDQRRMVGKCYVRGNDLELDSSDDWQTYH 181 Query: 169 YAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPN 228 C S + D G CQ G S FT+ + V G PG++ W+G Q E +D + Sbjct: 182 NEMCNS-NTDYLETGMCQLGTSGGFTQ-NTVYFGAPGAYNWKGNSYMIQRKE----WDLS 235 Query: 229 VYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDF--NGDGIDDFVSGVPRAARTLGMVYIY 286 YS K + Y+GY++ VG F + I V+G PR R +G V++ Sbjct: 236 EYSYKDPEDQG---------NLYIGYTMQVGSFILHPKNIT-IVTGAPRH-RHMGAVFLL 284 Query: 287 D---GKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVG 343 G ++ G Q+ AYFG ++A D+N D + D+ +GAP + +R K + G Sbjct: 285 SQEAGGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFER----KEEVGG 340 Query: 344 QVSVSLQRASGDFQ---TTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKK 400 + V + +A F + L+G A FG ++A +GD++QDGF DIA+ AP+ G K Sbjct: 341 AIYVFMNQAGTSFPAHPSLLLHGPSGSA-FGLSVASIGDINQDGFQDIAVGAPFEGLGK- 398 Query: 401 GIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVD 460 VYI++ S GL P Q++ G+ +FGYS+ G D+D+N YPDL+VG+ D Sbjct: 399 --VYIYHSSSKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLS-D 455 Query: 461 RAILYRARPVIT-VNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCL---KADGKGV 516 +L RARPVI V+ L P++L+ P SC V C ++ G Sbjct: 456 HIVLLRARPVINIVHKTLVPRPAVLD--------PALCTATSCVQVELCFAYNQSAGNPN 507 Query: 517 LPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDES 576 R + L D+ ++ +R F S S ++ M+C++L L D Sbjct: 508 YRRNITLAYTLEADRDRRPPRLR---FAGSESAVFHGFFSMPE---MRCQKLELLLMD-- 559 Query: 577 EFRDKLTPITIFMEYRLDYRTA-ADTTGLQ-----PILNQFTPANISRQAHILLDCGEDN 630 RDKL PI I M Y L R GL+ PILNQ + +CG DN Sbjct: 560 NLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPDN 619 Query: 631 VCKPKLEVS---VDSDQKKI----YIGDDNPLTLIVKAQN------QGEGAYEAELIVSI 677 C+ L++ V Q+K+ Y D L L + N GE A+EA L + + Sbjct: 620 KCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVV 679 Query: 678 PLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEM 737 P A + VR A N+T + C+LGNP K ++ + F V + Sbjct: 680 P-PALLLSSVRPPGAC--------QANET--IFCELGNPFKRNQRMELLIAFEVIGVTLH 728 Query: 738 DTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIR-GVSSPDHIFLPI--PNWEHKE 794 ++ LQ+ +S+ D + P++ L +L ++ +S +H + Sbjct: 729 TRDLQVQLQLSTSSHQDNLWPMI-----LTLLVDYTLQTSLSMVNHRLQSFFGGTVMGES 783 Query: 795 NPETEEDVGPVVQHIYEL--RNNGPSSFSKAMLHLQWPYKYNNNT-LLYILHYDIDG--- 848 +T EDVG +++ +++ G +L L+WPY+ +N LLY + G Sbjct: 784 GMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGS 843 Query: 849 -PMNCTSDMEINPLRIKISS--------LQTTEKNDTVAGQGERDHLITKRDLALSEGDI 899 P D+ INPL + +S + + D GQG + A SE + Sbjct: 844 WPCRPPGDL-INPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSE-TV 901 Query: 900 HTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVI 959 T G A C+ + C + D + VK+ +W TF+ + A+ Sbjct: 902 LTCATGRAHCVWLECPIP--DAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATL--- 956 Query: 960 EFPYKNLPIEDITNSTLVTTNVTWG--------IQPAPMPVPVWVIILAVLAGLLLLAVL 1011 F ++P ++ N T TW ++ P + +W++++AV AGLLLL ++ Sbjct: 957 -FLRTSIPTINMENKT------TWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLI 1009 Query: 1012 VFVMYRMGFFKRVR 1025 + ++++ FFKR R Sbjct: 1010 ILLLWKCDFFKRTR 1023 >gi|31657142 integrin, alpha 1 precursor [Homo sapiens] Length = 1179 Score = 211 bits (537), Expect = 3e-54 Identities = 223/886 (25%), Positives = 381/886 (43%), Gaps = 123/886 (13%) Query: 186 QGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDP--NVYSIKYNNQLATRTA 243 Q GFS +++ D V+LG G++ W G ++ + ++I+ + NV S K N LA Sbjct: 379 QTGFSAHYSQ-DWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLA---- 433 Query: 244 QAIFDDSYLGYSV-AVGDFNGDGIDDFVSGVPRAARTLGMVYIY---DGKNMSSLYNFTG 299 SYLGY+V + +GD + +++G PR T G V IY DG N+ L +G Sbjct: 434 ------SYLGYTVNSATASSGDVL--YIAGQPRYNHT-GQVIIYRMEDG-NIKILQTLSG 483 Query: 300 EQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSV-SLQRASGDFQ 357 EQ+ +YFG + TDI+ D D+ +GAP++M + +E G+V V +L + ++Q Sbjct: 484 EQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGT----EKEEQGKVYVYALNQTRFEYQ 539 Query: 358 -------------------TTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGED 398 TT+ ARFG+AIA + DL+ DGFNDI I AP +D Sbjct: 540 MSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLE-DD 598 Query: 399 KKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFG 458 G VYI++G + +Q + +++ FG S+ G D++ +G D+ +G G Sbjct: 599 HGGAVYIYHGSGKTIRKEYAQRIPSGGDGKTLK-FFGQSIHGEMDLNGDGLTDVTIGGLG 657 Query: 459 VDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFC--LKADGKGV 516 A L+ +R V V + P+ +N K C + G + C N C +K K Sbjct: 658 --GAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGK--ETVCINATVCFDVKLKSKED 713 Query: 517 LPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDES 576 + + Q + LD L+Q I R+ F ++ +N+T+ + +C + Y+ D+ Sbjct: 714 TIYEADLQYRVTLDSLRQ---ISRSFFSGTQERKVQRNITVRKS---ECTKHSFYMLDKH 767 Query: 577 EFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKL 636 +F+D + LD+ G P+L+ P ++ DCG C L Sbjct: 768 DFQDSV-------RITLDFNLTDPENG--PVLDDSLPNSVHEYIPFAKDCGNKEKCISDL 818 Query: 637 EVSVDSDQKKIYI--GDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALA 694 + V + +K + I ++ + + +N + AY IV F G+ EA+ Sbjct: 819 SLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGI----EAIQ 874 Query: 695 RLSCAFKTENQTRQVVCDLGNP-MKAGTQLLAGLRFSVHQQSEMDT-----SVKFDLQIQ 748 + SC + C +G P ++ G + + F + M+ S D + Sbjct: 875 KDSC-----ESNHNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEP 929 Query: 749 SSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQH 808 L D V V+ + + ++ +S HI + N E + ED+G + Sbjct: 930 PETLSDNV---VNISIPVKYEVGLQFYSSASEYHISIAA-NETVPEVINSTEDIGNEINI 985 Query: 809 IYELRNNGPSSFSKAMLHLQWPYKYNNN-TLLYILHYDIDGPMNCTSDMEINPLRIKISS 867 Y +R +G + L + +P +N +LY NC + +P I Sbjct: 986 FYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGK 1045 Query: 868 LQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAIL 927 TT DHL G I L C + I C + D + + Sbjct: 1046 KMTTST----------DHL--------KRGTI--LDCNTCKFATITCNLTSSDISQ---V 1082 Query: 928 YVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQP 987 V +LW TF+ + + +++ E +N + +++ + Sbjct: 1083 NVSLILWKPTFIKSYFSSLNLTIRG-------ELRSENASLVLSSSNQKRELAIQISKDG 1135 Query: 988 APMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQER 1033 P VP+WVI+L+ AGLLLL +L+ ++++GFFK RP +++ E+ Sbjct: 1136 LPGRVPLWVILLSAFAGLLLLMLLILALWKIGFFK--RPLKKKMEK 1179 Score = 49.3 bits (116), Expect = 2e-05 Identities = 42/145 (28%), Positives = 60/145 (41%), Gaps = 14/145 (9%) Query: 5 PRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRM 64 PR R R G L ++L C +FN+DV + +SGP FG+ V + + Sbjct: 3 PRPRARPGVAVACCWLLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWV 62 Query: 65 FL---LVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSH 121 + LVG PK T G V KC ++ D N + E K + Sbjct: 63 LIGSPLVGQPKNRT--------GDVYKCPVGRGESLPCVKLDLPVNTSI--PNVTEVKEN 112 Query: 122 QWFGAS-VRSKQDKILACAPLYHWR 145 FG++ V + LAC PLY +R Sbjct: 113 MTFGSTLVTNPNGGFLACGPLYAYR 137 >gi|116295258 integrin alpha 2 precursor [Homo sapiens] Length = 1181 Score = 199 bits (507), Expect = 9e-51 Identities = 232/884 (26%), Positives = 385/884 (43%), Gaps = 117/884 (13%) Query: 186 QGGFSIDFTKADRVL-LGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQ 244 Q GFS D++ + +L LG G+F W G ++ + + + Q + Q Sbjct: 380 QVGFSADYSSQNDILMLGAVGAFGWSGTIVQKT----------SHGHLIFPKQAFDQILQ 429 Query: 245 AIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIY---DGKNMSSLYNFTGEQ 301 SYLGYSVA + FV+G PRA T G + +Y + N++ + G+Q Sbjct: 430 DRNHSSYLGYSVAA--ISTGESTHFVAGAPRANYT-GQIVLYSVNENGNITVIQAHRGDQ 486 Query: 302 MAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK 360 + +YFG + + D++ D DV +GAP++M SD K +E G+V + + Q Sbjct: 487 IGSYFGSVLCSVDVDKDTITDVLLVGAPMYM---SDLKKEE-GRVYLFTIKEGILGQHQF 542 Query: 361 LNGFEVF--ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPS 418 L G E RFGSAIA L D++ DGFND+ + +P ++ G VYI+NG + S Sbjct: 543 LEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQN-SGAVYIYNGHQGTIRTKYS 601 Query: 419 Q-ILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGL 477 Q IL A RS FG S+ G D++ + D+ +GAFG + + ++ + V Sbjct: 602 QKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFG--QVVQLWSQSIADVAIEA 659 Query: 478 EVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQKG 536 P + NK + LK+ CF+ +F P K N QV ++ + L G Sbjct: 660 SFTPEKITLVNKNAQI---ILKL-CFSAKF---------RPTKQNNQVAIVYNITLDADG 706 Query: 537 ----AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYR 592 R LF + KNM +++ C E I Y+++ S+ + L + R Sbjct: 707 FSSRVTSRGLFKENNERCLQKNMVVNQA--QSCPEHIIYIQEPSDVVNSL-------DLR 757 Query: 593 LDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKL-----EVSVDSDQKKI 647 +D + + G P L ++ DCGED +C L ++ +Q I Sbjct: 758 VD--ISLENPGTSPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFI 815 Query: 648 YIGDDNPLTLIVKAQNQGEGAYEAELIVSIP---LQADFIGVVRNNEALARLSCAFKTEN 704 + LT V +N+ E AY ++V A F V E +++ + K+ Sbjct: 816 VSNQNKRLTFSVTLKNKRESAYNTGIVVDFSENLFFASFSLPVDGTEVTCQVAASQKS-- 873 Query: 705 QTRQVVCDLGNP-MKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHK 763 V CD+G P +K Q+ + F + Q+ + + + S +K +V+ K Sbjct: 874 ----VACDVGYPALKREQQVTFTINFDFNLQNLQNQASLSFQALSESQEENKADNLVNLK 929 Query: 764 VDLAVLAAVEIRGVSSPDHIFLPIPNWEHKEN-PETEEDVGPVVQHIYELR---NNGPSS 819 + L L EI S + F I + + + + EDVGP + I+ L+ + P S Sbjct: 930 IPL--LYDAEIHLTRSTNINFYEISSDGNVPSIVHSFEDVGP--KFIFSLKVTTGSVPVS 985 Query: 820 FSKAMLHLQWPYKYNNNTLLYILHYDID--GPMNCTSDMEINPLRIKISSLQTTEKNDTV 877 + ++H+ Y N L+Y+ D G ++C +D INPL+I +S + K++ Sbjct: 986 MATVIIHIP-QYTKEKNPLMYLTGVQTDKAGDISCNAD--INPLKIGQTSSSVSFKSENF 1042 Query: 878 AGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTET 937 E L C A C + C + + + V + +W T Sbjct: 1043 RHTKE-------------------LNCRTASCSNVTCWLKDVHMKGEYFVNVTTRIWNGT 1083 Query: 938 FMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVI 997 F + Q +++ +A+ + + + IED T VT + VP VI Sbjct: 1084 FASSTFQ----TVQLTAAAEINTYNPEIYVIEDNT----VTIPLMIMKPDEKAEVPTGVI 1135 Query: 998 ILAVLAGLLLLAVLVFVMYRMGFFKR-----VRPPQEEQEREQL 1036 I +++AG+LLL LV +++++GFFKR + P E E +L Sbjct: 1136 IGSIIAGILLLLALVAILWKLGFFKRKYEKMTKNPDEIDETTEL 1179 Score = 43.5 bits (101), Expect = 0.001 Identities = 42/156 (26%), Positives = 65/156 (41%), Gaps = 18/156 (11%) Query: 10 RLGPRGLPLLL----SGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMF 65 R G LPLLL S +L C A+N+ + +SGP FG+AV F+ + + Sbjct: 5 RTGAAPLPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGN--W 62 Query: 66 LLVGAPKANTTQPGIVEGGQVLKCDWS-STRRCQPIEFDATGNRDYAKDDPLEFKSHQWF 124 LLVG+P + + + G V KC ST C+ + + + + E K++ Sbjct: 63 LLVGSPWSGFPENRM---GDVYKCPVDLSTATCEKLNLQTS----TSIPNVTEMKTNMSL 115 Query: 125 GASVRSKQDK--ILACAPLYHWRTEMKQEREPVGTC 158 G + L C PL W + + G C Sbjct: 116 GLILTRNMGTGGFLTCGPL--WAQQCGNQYYTTGVC 149 >gi|52485853 integrin, alpha 11 precursor [Homo sapiens] Length = 1188 Score = 171 bits (434), Expect = 3e-42 Identities = 211/892 (23%), Positives = 359/892 (40%), Gaps = 120/892 (13%) Query: 181 GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLAT 240 G Q GFS + D VLLG G++ W G ++ + A V + Y ++ +L Sbjct: 363 GLEMSQTGFSSHVVE-DGVLLGAVGAYDWNGAVLKETSAGKVIPLRES-YLKEFPEELKN 420 Query: 241 RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSL---YNF 297 A YLGY+V + G +V+G PR T G V ++ N SL Sbjct: 421 HGA-------YLGYTVTSVVSSRQG-RVYVAGAPRFNHT-GKVILFTMHNNRSLTIHQAM 471 Query: 298 TGEQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSLQRASGDF 356 G+Q+ +YFG + + DI+GD DV +GAP++ + G + V ++ +L +G Sbjct: 472 RGQQIGSYFGSEITSVDIDGDGVTDVLLVGAPMYFNEGRERGKVYVYELRQNLFVYNG-- 529 Query: 357 QTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAV 416 T K + ARFGS+IA + DL+QD +ND+ + AP ++ G +YIF+G + Sbjct: 530 -TLKDSHSYQNARFGSSIASVRDLNQDSYNDVVVGAPL-EDNHAGAIYIFHGFRGSILKT 587 Query: 417 PSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAG 476 P Q + A + FG S+ G D++++G DL VGA G A++ +RPV+ +NA Sbjct: 588 PKQRITASELATGL-QYFGCSIHGQLDLNEDGLIDLAVGALG--NAVILWSRPVVQINAS 644 Query: 477 LEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKG 536 L PS +N ++ C G +C C + P V + + + Sbjct: 645 LHFEPSKINIFHRDCKRSGR--DATCLAAFLCFTP--IFLAPHFQTTTVGIRYNATMDER 700 Query: 537 AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYR 596 L + + G CE + ++ D +++ + P+T +EY L Sbjct: 701 RYTPRAHLDEGGDRFTNRAVLLSSGQELCERINFHVLDTADY---VKPVTFSVEYSL--- 754 Query: 597 TAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSD------------- 643 + P+L+ P + C ED C P L + SD Sbjct: 755 ---EDPDHGPMLDDGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLR 811 Query: 644 -------------QKKIYIGDDNPLTLIVKA--QNQGEGAYEAELIVSIPLQADFIGVVR 688 ++I + + V+A +N+GE AY L +S F +++ Sbjct: 812 KPAQDCSAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNISQSANLQFASLIQ 871 Query: 689 NNEALARLSCAFKTENQTRQVVCDLGNPM---KAGTQLLAGLRFSVH---QQSEMDTSVK 742 ++ + C E + ++ VC++ P KA FS E++ + Sbjct: 872 KEDSDGSIECV-NEERRLQKQVCNVSYPFFRAKAKVAFRLDFEFSKSIFLHHLEIELAAG 930 Query: 743 FDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETE--E 800 D + S D V+P+ H L A V SS H +E K N E + Sbjct: 931 SDSNERDSTKEDNVAPLRFH---LKYEADVLFTRSSSLSH-------YEVKPNSSLERYD 980 Query: 801 DVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINP 860 +GP I+ ++N G M+ + P + L L + N + ++ N Sbjct: 981 GIGPPFSCIFRIQNLGLFPIHGMMMKITIPIATRSGNRLLKLRDFLTDEANTSCNIWGNS 1040 Query: 861 LRIKISSLQTTEKNDTVAGQGERDHLITKRDLAL---SEGDIHTLGCGVAQCLKIVCQVG 917 + + ++ + D + ++ L E + H LG + LK + Sbjct: 1041 TEYRPTPVEEDLRRAPQLNHSNSDVVSINCNIRLVPNQEINFHLLGNLWLRSLKAL---- 1096 Query: 918 RLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLV 977 + KS + V + L + Q HS + E P + + E + Sbjct: 1097 ---KYKSMKIMVNAAL--------QRQFHSPFIFRE------EDPSRQIVFE-------I 1132 Query: 978 TTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQE 1029 + W VP+W+I+ + L GLLLLA+LV ++++GFF+ R +E Sbjct: 1133 SKQEDW-------QVPIWIIVGSTLGGLLLLALLVLALWKLGFFRSARRRRE 1177 Score = 35.8 bits (81), Expect = 0.22 Identities = 40/149 (26%), Positives = 56/149 (37%), Gaps = 16/149 (10%) Query: 13 PRGLPLLLSGLLLP-LCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAP 71 PRGL + + L P FN+D P G ++FG+ V S +L+VGAP Sbjct: 4 PRGLVVAWALSLWPGFTDTFNMDTRKPRVIPGSRTAFFGYTVQ--QHDISGNKWLVVGAP 61 Query: 72 KANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRS- 130 G + G V KC C + + E K + G S+ + Sbjct: 62 LETN---GYQKTGDVYKCP-VIHGNCTKLNLGRV-----TLSNVSERKDNMRLGLSLATN 112 Query: 131 -KQDKILACAPLYHWRTEMKQEREPVGTC 158 K + LAC+PL W E G C Sbjct: 113 PKDNSFLACSPL--WSHECGSSYYTTGMC 139 >gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] Length = 1152 Score = 168 bits (426), Expect = 2e-41 Identities = 204/861 (23%), Positives = 362/861 (42%), Gaps = 100/861 (11%) Query: 186 QGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRT-AQ 244 Q GFS T ++ LL GS+ W G + +Y+ K + T Sbjct: 352 QEGFSAAIT-SNGPLLSTVGSYDWAGGVF--------------LYTSKEKSTFINMTRVD 396 Query: 245 AIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKN--MSSLYNFTGEQM 302 + +D+YLGY+ A+ + + V G PR +G+V ++ S N G Q+ Sbjct: 397 SDMNDAYLGYAAAI--ILRNRVQSLVLGAPRYQH-IGLVAMFRQNTGMWESNANVKGTQI 453 Query: 303 AAYFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVS-LQRASGDFQTTK 360 AYFG S+ + D++ + D V IGAP + ++ G QVSV L R +Q Sbjct: 454 GAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGG------QVSVCPLPRGRARWQCDA 507 Query: 361 L---NGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS-TGLNAV 416 + + + RFG+A+ LGD++ D D+AI AP G ED +G VY+F+G S +G++ Sbjct: 508 VLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFHGTSGSGISPS 566 Query: 417 PSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAG 476 SQ + G + + FG S+ G D+ +G DL VGA G +L R++PV+ V A Sbjct: 567 HSQRIAGSKLSPRL-QYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRSQPVLRVKAI 623 Query: 477 LEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQK 535 +E P + ++ C+ K VR CL K R Q++ ++ L Sbjct: 624 MEFNPREVARNVFECNDQVVKGK-EAGEVRVCLHVQ-KSTRDRLREGQIQSVVTYDLALD 681 Query: 536 GAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDY 595 + +++ + + ++ T G CE L L + E D ++PI + + + L Sbjct: 682 SGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIE--DPVSPIVLRLNFSLVG 739 Query: 596 RTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNP 654 + L+P+L + + +CG DN+C+ L ++ + +G Sbjct: 740 TPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPRE 799 Query: 655 LTLIVKAQNQGEGAYEAELIVSIPLQADF--IGVVRNNEALA--RLSC--AFKTE--NQT 706 + V +N GE +Y ++ PL + + ++N + RL+C A TE Sbjct: 800 FNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGAL 859 Query: 707 RQVVCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPV---VSH 762 + C + +P+ +++ + F V ++ + + + S N + + + Sbjct: 860 KSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLEL 919 Query: 763 KVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSK 822 V AV V GVS+ +L N E+ V+QH Y++ N G S Sbjct: 920 PVKYAVYMVVTSHGVSTK---YL---------NFTASENTSRVMQHQYQVSNLGQRSLPI 967 Query: 823 AMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGE 882 +++ L P + N + D P Q T + + Sbjct: 968 SLVFLV-PVRLNQTVIW-------DRP-------------------QVTFSENLSSTCHT 1000 Query: 883 RDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKE 942 ++ L + D + C +A C +I C + + +K L + ++ K Sbjct: 1001 KERLPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYI-KT 1059 Query: 943 NQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVL 1002 + NH + S+A + + LP V + ++P +P P+ +I+ + + Sbjct: 1060 SHNH-LLIVSTAEILFNDSVFTLLP----GQGAFVRSQTETKVEPFEVPNPLPLIVGSSV 1114 Query: 1003 AGLLLLAVLVFVMYRMGFFKR 1023 GLLLLA++ +Y++GFFKR Sbjct: 1115 GGLLLLALITAALYKLGFFKR 1135 Score = 31.6 bits (70), Expect = 4.1 Identities = 36/137 (26%), Positives = 54/137 (39%), Gaps = 23/137 (16%) Query: 25 LPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGG 84 L LC FNLD ++ + FG +V V SR ++VGAP+ + G Sbjct: 11 LTLCHGFNLDTENAMTFQ-ENARGFGQSV---VQLQGSR--VVVGAPQEIVAAN---QRG 61 Query: 85 QVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLE-FKSHQWFGASVRSKQDKILACAPLYH 143 + +CD+ ST C+PI P+E + + ++LAC P H Sbjct: 62 SLYQCDY-STGSCEPIRLQV----------PVEAVNMSLGLSLAATTSPPQLLACGPTVH 110 Query: 144 WRTEMKQEREPVGTCFL 160 + G CFL Sbjct: 111 --QTCSENTYVKGLCFL 125 >gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] Length = 1153 Score = 167 bits (422), Expect = 6e-41 Identities = 200/857 (23%), Positives = 358/857 (41%), Gaps = 91/857 (10%) Query: 186 QGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRT-AQ 244 Q GFS T ++ LL GS+ W G + +Y+ K + T Sbjct: 352 QEGFSAAIT-SNGPLLSTVGSYDWAGGVF--------------LYTSKEKSTFINMTRVD 396 Query: 245 AIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKN--MSSLYNFTGEQM 302 + +D+YLGY+ A+ + + V G PR +G+V ++ S N G Q+ Sbjct: 397 SDMNDAYLGYAAAI--ILRNRVQSLVLGAPRYQH-IGLVAMFRQNTGMWESNANVKGTQI 453 Query: 303 AAYFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKL 361 AYFG S+ + D++ + D V IGAP + ++ G++ R D Sbjct: 454 GAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGQRARWQCDAVLYGE 513 Query: 362 NGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS-TGLNAVPSQI 420 G + + RFG+A+ LGD++ D D+AI AP G ED +G VY+F+G S +G++ SQ Sbjct: 514 QG-QPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFHGTSGSGISPSHSQR 571 Query: 421 LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY 480 + G + + FG S+ G D+ +G DL VGA G +L R++PV+ V A +E Sbjct: 572 IAGSKLSPRL-QYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRSQPVLRVKAIMEFN 628 Query: 481 PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQKGAIR 539 P + ++ C+ K VR CL K R Q++ ++ L Sbjct: 629 PREVARNVFECNDQVVKGK-EAGEVRVCLHVQ-KSTRDRLREGQIQSVVTYDLALDSGRP 686 Query: 540 RALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAA 599 + +++ + + ++ T G CE L L + E D ++PI + + + L + Sbjct: 687 HSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIE--DPVSPIVLRLNFSLVGTPLS 744 Query: 600 DTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNPLTLI 658 L+P+L + + +CG DN+C+ L ++ + +G + Sbjct: 745 AFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPREFNVT 804 Query: 659 VKAQNQGEGAYEAELIVSIPLQADF--IGVVRNNEALA--RLSC--AFKTE--NQTRQVV 710 V +N GE +Y ++ PL + + ++N + RL+C A TE + Sbjct: 805 VTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTS 864 Query: 711 CDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPV---VSHKVDL 766 C + +P+ +++ + F V ++ + + + S N + + + V Sbjct: 865 CSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKY 924 Query: 767 AVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLH 826 AV V GVS+ +L N E+ V+QH Y++ N G S +++ Sbjct: 925 AVYMVVTSHGVSTK---YL---------NFTASENTSRVMQHQYQVSNLGQRSLPISLVF 972 Query: 827 LQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHL 886 L P + N + D P Q T + + ++ L Sbjct: 973 LV-PVRLNQTVIW-------DRP-------------------QVTFSENLSSTCHTKERL 1005 Query: 887 ITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNH 946 + D + C +A C +I C + + +K L + ++ K + NH Sbjct: 1006 PSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYI-KTSHNH 1064 Query: 947 SYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLL 1006 + S+A + + LP V + ++P +P P+ +I+ + + GLL Sbjct: 1065 -LLIVSTAEILFNDSVFTLLP----GQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLL 1119 Query: 1007 LLAVLVFVMYRMGFFKR 1023 LLA++ +Y++GFFKR Sbjct: 1120 LLALITAALYKLGFFKR 1136 Score = 31.6 bits (70), Expect = 4.1 Identities = 36/137 (26%), Positives = 54/137 (39%), Gaps = 23/137 (16%) Query: 25 LPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGG 84 L LC FNLD ++ + FG +V V SR ++VGAP+ + G Sbjct: 11 LTLCHGFNLDTENAMTFQ-ENARGFGQSV---VQLQGSR--VVVGAPQEIVAAN---QRG 61 Query: 85 QVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLE-FKSHQWFGASVRSKQDKILACAPLYH 143 + +CD+ ST C+PI P+E + + ++LAC P H Sbjct: 62 SLYQCDY-STGSCEPIRLQV----------PVEAVNMSLGLSLAATTSPPQLLACGPTVH 110 Query: 144 WRTEMKQEREPVGTCFL 160 + G CFL Sbjct: 111 --QTCSENTYVKGLCFL 125 >gi|34452173 integrin alpha X precursor [Homo sapiens] Length = 1163 Score = 167 bits (422), Expect = 6e-41 Identities = 217/882 (24%), Positives = 353/882 (40%), Gaps = 106/882 (12%) Query: 186 QGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQA 245 Q GFS FT D +LG GSF W G Y PN+ N + Sbjct: 353 QEGFSAVFTP-DGPVLGAVGSFTWSGGAFL---------YPPNMSPTFINMSQENVDMR- 401 Query: 246 IFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAART-LGMVYIYDGKNMSSLYNFTGEQMAA 304 DSYLGYS + + G + V G PR T +++ + TG Q+ + Sbjct: 402 ---DSYLGYSTELALWKG--VQSLVLGAPRYQHTGKAVIFTQVSRQWRMKAEVTGTQIGS 456 Query: 305 YFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNG 363 YFG S+ + D++ D D V IGAP + ++ G++ V + +R D G Sbjct: 457 YFGASLCSVDVDSDGSTDLVLIGAPHYYEQTRGGQVS-VCPLPRGWRRWWCDAVLYGEQG 515 Query: 364 FEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNG-RSTGLNAVPSQILE 422 + RFG+A+ LGD++ D D+ I AP G E+ +G VY+F+G ++ SQ + Sbjct: 516 HP-WGRFGAALTVLGDVNGDKLTDVVIGAP-GEEENRGAVYLFHGVLGPSISPSHSQRIA 573 Query: 423 GQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPS 482 G + S FG ++ G D+ ++G DL VGA G + +L R RPV+ V ++ P+ Sbjct: 574 GSQLS-SRLQYFGQALSGGQDLTQDGLVDLAVGARG--QVLLLRTRPVLWVGVSMQFIPA 630 Query: 483 ILNQDNKTCSLPGTALKVSCFNVRFCLKAD--GKGVLPRKLNFQVELLLDKLKQKGAIR- 539 + + C + + CL D K +L + + Q + LD G + Sbjct: 631 EIPRSAFECR-EQVVSEQTLVQSNICLYIDKRSKNLLGSR-DLQSSVTLDLALDPGRLSP 688 Query: 540 RALFLYSRSPSHSKNMTISR----GGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDY 595 RA F +KN ++SR G CE L S D +TPIT+ + + L Sbjct: 689 RATF------QETKNRSLSRVRVLGLKAHCENFNLLL--PSCVEDSVTPITLRLNFTLVG 740 Query: 596 RTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNP 654 + L+P+L + +CG D++C+ L +S K + +G + Sbjct: 741 KPLLAFRNLRPMLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLE 800 Query: 655 LTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNE----ALARLSC--AFKTENQTRQ 708 L V N GE +Y + S P + V + L+C A T Sbjct: 801 LNAEVMVWNDGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWS 860 Query: 709 VVCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLA 767 C + + + + G Q+ F V ++ + + + S N + S + +++L Sbjct: 861 TSCRINHLIFRGGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSK-TTFQLELP 919 Query: 768 VLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHL 827 V AV V S F N+ E+EE V H Y++ N G ++ Sbjct: 920 VKYAVYT--VVSSHEQFTKYLNFS-----ESEEKESHVAMHRYQVNNLGQRDL-PVSINF 971 Query: 828 QWPYKYNNNTLLYILHYDIDGPMN----CTSDMEINPLRIKISSLQTTEKNDTVAGQGER 883 P + N + + ++ P N C+S+ P ++ +Q KN Sbjct: 972 WVPVELNQEAVW--MDVEVSHPQNPSLRCSSEKIAPPASDFLAHIQ---KNP-------- 1018 Query: 884 DHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLL---WTETFMN 940 L C +A CL+ C V + +K L W + Sbjct: 1019 -----------------VLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQ 1061 Query: 941 KENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILA 1000 K+ S+ S A Y LP ++ + T ++ + P +I+ + Sbjct: 1062 KK-----VSVVSVAEITFDTSVYSQLPGQE----AFMRAQTTTVLEKYKVHNPTPLIVGS 1112 Query: 1001 VLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENG 1042 + GLLLLA++ V+Y++GFFKR E+ Q+ P ENG Sbjct: 1113 SIGGLLLLALITAVLYKVGFFKRQYKEMMEEANGQIAP-ENG 1153 >gi|148728188 integrin, alpha E precursor [Homo sapiens] Length = 1179 Score = 159 bits (402), Expect = 1e-38 Identities = 148/517 (28%), Positives = 226/517 (43%), Gaps = 52/517 (10%) Query: 178 DADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQ 237 DA Q GFS +VLLG G+F W G + YD ++ NQ Sbjct: 395 DALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALL---------YDTRSRRGRFLNQ 445 Query: 238 LATRTAQA-IFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIY-DGKNMSSLY 295 A A A SYLGY+VAV + +++G PR + + +G+ S L Sbjct: 446 TAAAAADAEAAQYSYLGYAVAV--LHKTCSLSYIAGAPRYKHHGAVFELQKEGREASFLP 503 Query: 296 NFTGEQMAAYFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVSLQRASG 354 GEQM +YFG + DI+ D D + + AP + G +G++ L G Sbjct: 504 VLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEGRVYVY-----RLSEQDG 558 Query: 355 DFQTTK-LNGFEVF--ARFGSAIAPLGDLDQDGFNDIAIAAP---YGGED--KKGIVYIF 406 F + L+G F ARFG A+A +GDL QD D+AI AP +G +D G VYI+ Sbjct: 559 SFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIY 618 Query: 407 NGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYR 466 NG GL+A PSQ + A + FG SM G DI +G D+ VG G +A+++R Sbjct: 619 NGHWDGLSASPSQRIRASTVAPGL-QYFGMSMAGGFDISGDGLADITVGTLG--QAVVFR 675 Query: 467 ARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVE 526 +RPV+ + + PS L G CF + A G+ LNF ++ Sbjct: 676 SRPVVRLKVSMAFTPSAL-----PIGFNGVVNVRLCFEISSVTTASESGLREALLNFTLD 730 Query: 527 LLLDKLKQK---GAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEF--RDK 581 + + K +++ +R L S G CE+L+ + E E D Sbjct: 731 VDVGKQRRRLQCSDVRSCLGCLREWSS----------GSQLCEDLL-LMPTEGELCEEDC 779 Query: 582 LTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD 641 + ++ + Y+L T QPIL+++T Q C C +L+++ Sbjct: 780 FSNASVKVSYQLQ-TPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLATT 838 Query: 642 SDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIP 678 Q+++ +G LTL + N GE +Y + ++ P Sbjct: 839 VSQQELVVGLTKELTLNINLTNSGEDSYMTSMALNYP 875 Score = 31.2 bits (69), Expect = 5.3 Identities = 12/28 (42%), Positives = 21/28 (75%) Query: 996 VIILAVLAGLLLLAVLVFVMYRMGFFKR 1023 +II + GLL+L V++ ++++ GFFKR Sbjct: 1127 IIIKGSVGGLLVLIVILVILFKCGFFKR 1154 >gi|38569398 integrin, alpha 10 precursor [Homo sapiens] Length = 1167 Score = 149 bits (377), Expect = 1e-35 Identities = 155/553 (28%), Positives = 253/553 (45%), Gaps = 54/553 (9%) Query: 181 GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLAT 240 G Q GFS K D +L G G++ W G ++ E + P +++ A Sbjct: 369 GLEMSQIGFSTHRLK-DGILFGMVGAYDWGGSVLW---LEGGHRLFPPRMALEDEFPPAL 424 Query: 241 RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSL---YNF 297 + A YLGYSV+ G G F+SG PR R G V + K ++ + Sbjct: 425 QNHAA-----YLGYSVSSMLLRG-GRRLFLSGAPRF-RHRGKVIAFQLKKDGAVRVAQSL 477 Query: 298 TGEQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSL--QRASG 354 GEQ+ +YFG + D + D DV + AP+F+ G K E G+V V L Q++ Sbjct: 478 QGEQIGSYFGSELCPLDTDRDGTTDVLLVAAPMFL--GPQNK--ETGRVYVYLVGQQSLL 533 Query: 355 DFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLN 414 Q T ARFG A+ L DL+QDGF D+A+ AP + +G +Y+++G +G+ Sbjct: 534 TLQGTLQPEPPQDARFGFAMGALPDLNQDGFADVAVGAPL-EDGHQGALYLYHGTQSGVR 592 Query: 415 AVPSQILEGQWAARSMPPS---FGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVI 471 P+Q + AA SMP + FG S+ G D+D + D+ VGA G AIL +RP++ Sbjct: 593 PHPAQRI----AAASMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGA--AILLSSRPIV 646 Query: 472 TVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVEL-LLD 530 + LEV P ++ + C G + C C + + P + + Q + Sbjct: 647 HLTPSLEVTPQAISVVQRDCRRRGQ--EAVCLTAALCFQVTSR--TPGRWDHQFYMRFTA 702 Query: 531 KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFME 590 L + A RA F S + + +S G + CE+L ++ D S++ L P+ + + Sbjct: 703 SLDEWTAGARAAFDGSGQRLSPRRLRLSVGN-VTCEQLHFHVLDTSDY---LRPVALTVT 758 Query: 591 YRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSD----QKK 646 + LD +TT P+LN+ +P +I + DCG DN C L + V+ D +K Sbjct: 759 FALD-----NTTKPGPVLNEGSPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKA 813 Query: 647 IYI--GDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTEN 704 ++ G + + +N+ E AY L + + E+ ++ CA + + Sbjct: 814 PFVVRGGRRKVLVSTTLENRKENAYNTSLSLIFSRNLHLASLTPQRESPIKVECAAPSAH 873 Query: 705 QTRQVVCDLGNPM 717 +C +G+P+ Sbjct: 874 AR---LCSVGHPV 883 Score = 65.1 bits (157), Expect = 3e-10 Identities = 36/130 (27%), Positives = 70/130 (53%), Gaps = 7/130 (5%) Query: 908 QCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLP 967 QC + C +G+L +G + + L+ E F + KS + E + Sbjct: 1044 QCQVVRCHLGQLAKGTEVSVGLLRLVHNEFFRRAK-------FKSLTVVSTFELGTEEGS 1096 Query: 968 IEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPP 1027 + +T ++ + ++ +Q P+ + +W++I +VL GLLLLA+LVF ++++GFF + P Sbjct: 1097 VLQLTEASRWSESLLEVVQTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIP 1156 Query: 1028 QEEQEREQLQ 1037 +EE+ E+L+ Sbjct: 1157 EEEKREEKLE 1166 Score = 35.0 bits (79), Expect = 0.37 Identities = 34/127 (26%), Positives = 46/127 (36%), Gaps = 9/127 (7%) Query: 16 LPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANT 75 LPL+ L LC FNLD P + GP + FG++V V + ++LVGAP Sbjct: 11 LPLVF---LTGLCSPFNLDEHHPRLFPGPPEAEFGYSVLQHV--GGGQRWMLVGAP---W 62 Query: 76 TQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKI 135 P G V +C P G+ H Sbjct: 63 DGPSGDRRGDVYRCPVGGAHNA-PCAKGHLGDYQLGNSSHPAVNMHLGMSLLETDGDGGF 121 Query: 136 LACAPLY 142 +ACAPL+ Sbjct: 122 MACAPLW 128 >gi|62548866 integrin, alpha D precursor [Homo sapiens] Length = 1161 Score = 147 bits (370), Expect = 7e-35 Identities = 205/862 (23%), Positives = 356/862 (41%), Gaps = 107/862 (12%) Query: 186 QGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQA 245 Q GFS T D + LG GSF W G Y PN+ N + Sbjct: 352 QEGFSTALTM-DGLFLGAVGSFSWSGGAFL---------YPPNMSPTFINMSQENVDMR- 400 Query: 246 IFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAART-LGMVYIYDGKNMSSLYNFTGEQMAA 304 DSYLGYS + + G + + V G PR T +++ + TG Q+ + Sbjct: 401 ---DSYLGYSTELALWKG--VQNLVLGAPRYQHTGKAVIFTQVSRQWRKKAEVTGTQIGS 455 Query: 305 YFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVS-LQRASGDFQTTKLN 362 YFG S+ + D++ D D + IGAP + ++ G QVSV L R +Q + Sbjct: 456 YFGASLCSVDVDSDGSTDLILIGAPHYYEQTRGG------QVSVCPLPRGRVQWQCDAVL 509 Query: 363 GFEV---FARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS-TGLNAVPS 418 E + RFG+A+ LGD+++D D+AI AP G ++ +G VY+F+G S +G++ S Sbjct: 510 RGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAP-GEQENRGAVYLFHGASESGISPSHS 568 Query: 419 Q-ILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGL 477 Q I Q + R FG ++ G D+ ++G DL VGA G + +L R+ PV+ V + Sbjct: 569 QRIASSQLSPRLQ--YFGQALSGGQDLTQDGLMDLAVGARG--QVLLLRSLPVLKVGVAM 624 Query: 478 EVYPSILNQDNKTC-SLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKG 536 P + + C +AL+ + CL K L + + Q + D G Sbjct: 625 RFSPVEVAKAVYRCWEEKPSALEAG--DATVCLTIQ-KSSLDQLGDIQSSVRFDLALDPG 681 Query: 537 AI-RRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDY 595 + RA+F +++P+ ++ T+ G + CE L L D E D ++PI + + + L Sbjct: 682 RLTSRAIFNETKNPTLTRRKTLGLG--IHCETLKLLLPDCVE--DVVSPIILHLNFSLVR 737 Query: 596 RTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNP 654 L+P+L + + +CG+D +C+ L V++ S + + +G Sbjct: 738 EPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTLSFSGLQTLTVGSSLE 797 Query: 655 LTLIVKAQNQGEGAYEAELIVSIPLQADFIGV----VRNNEALARLSC-AFKTENQ-TRQ 708 L +IV N GE +Y + + P V + +++ RL+C TE++ R Sbjct: 798 LNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRS 857 Query: 709 VVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAV 768 C + +P+ H+ S V FD+ +++ + ++ + Sbjct: 858 SRCSVNHPI-------------FHEGSNGTFIVTFDVSYKAT---------LGDRMLMRA 895 Query: 769 LAAVEIRGVSSPDHIF---LPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAML 825 A+ E SS F LP+ + EE N +S K M Sbjct: 896 SASSENNKASSSKATFQLELPVKYAVYTMISRQEESTKYF---------NFATSDEKKMK 946 Query: 826 HLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKN-DTVAGQGERD 884 + Y+ NN + D+ +N + +N + + ++ ++ V+ + Sbjct: 947 EAEHRYRVNN-----LSQRDLAISINFWVPVLLNGVAVWDVVMEAPSQSLPCVSERKPPQ 1001 Query: 885 HLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLL---WTETFMNK 941 H D L C +A CL+ C V + +K L W + K Sbjct: 1002 H----SDFLTQISRSPMLDCSIADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQK 1057 Query: 942 ENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAV 1001 + + S A Y LP ++ + + ++ + + +I+ + Sbjct: 1058 K-----VLVVSVAEITFDTSVYSQLPGQE----AFMRAQMEMVLEEDEVYNAIPIIMGSS 1108 Query: 1002 LAGLLLLAVLVFVMYRMGFFKR 1023 + LLLLA++ +Y++GFFKR Sbjct: 1109 VGALLLLALITATLYKLGFFKR 1130 Score = 32.3 bits (72), Expect = 2.4 Identities = 39/133 (29%), Positives = 54/133 (40%), Gaps = 29/133 (21%) Query: 15 GLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAP--- 71 G LLLS +L FNLDV+ P + G + V F SR L+VGAP Sbjct: 4 GTVLLLS--VLASYHGFNLDVEEPTIFQEDAGGFGQSVVQF----GGSR--LVVGAPLEV 55 Query: 72 -KANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRS 130 AN T G++ C ++T CQPI + + + + AS Sbjct: 56 VAANQT-------GRLYDCA-AATGMCQPIPL-------HIRPEAVNMSLGLTLAASTNG 100 Query: 131 KQDKILACAPLYH 143 ++LAC P H Sbjct: 101 --SRLLACGPTLH 111 >gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] Length = 1086 Score = 123 bits (308), Expect = 1e-27 Identities = 152/602 (25%), Positives = 254/602 (42%), Gaps = 65/602 (10%) Query: 175 QDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKY 234 QD+ + G S D ++ V+ G G+ W G + ++ + + + Sbjct: 257 QDLTSFNMELSSSGISADLSRGHAVV-GAVGAKDWAGGFL-----DLKADLQDDTF---I 307 Query: 235 NNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYD----GKN 290 N+ T +A YLGY+V + SG PR +G V ++ G + Sbjct: 308 GNEPLTPEVRA----GYLGYTVTWLP-SRQKTSLLASGAPRYQH-MGRVLLFQEPQGGGH 361 Query: 291 MSSLYNFTGEQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSL 349 S + G Q+ +YFG + D++ D ++ IGAPLF Q G+V + Sbjct: 362 WSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGE------QRGGRVFIYQ 415 Query: 350 QRASGDFQTTKLNGFEVF--ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFN 407 +R G + ++L G + RFG AI L D++ DG D+A+ AP +++G VYIFN Sbjct: 416 RRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFN 472 Query: 408 GRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRA 467 GR GL+ PSQ +EG + FG S+ G D++ +G D+ VGA + I+ + Sbjct: 473 GRHGGLSPQPSQRIEGTQVLSGI-QWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSS 529 Query: 468 RPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVEL 527 RPV+ + + P+ + CS + N+ C + K ++P+ V Sbjct: 530 RPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQI--KSLIPQFQGRLVAN 587 Query: 528 LLDKLKQKG--AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPI 585 L L+ G RR LF R H I+ M C + + +D ++PI Sbjct: 588 LTYTLQLDGHRTRRRGLFPGGR---HELRRNIAVTTSMSCTDFSFHF--PVCVQDLISPI 642 Query: 586 TIFMEYRL--------DYRTAADTTGLQPILNQFTPANISRQAHILLD--CGEDNVCKPK 635 + + + L D R D + PIL P+ S I + CGED C+ Sbjct: 643 NVSLNFSLWEEEGTPRDQRAGKD---IPPILR---PSLHSETWEIPFEKNCGEDKKCEAN 696 Query: 636 LEVSVD-SDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGV-VRNNEAL 693 L VS + + + + L++ + N E AY +L + P F V + + Sbjct: 697 LRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQ 756 Query: 694 ARLSCAFKTENQ---TRQVVCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQS 749 +SC E +R + C++ +P+ KAG + + F+ S SV+ + Sbjct: 757 IPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTC 816 Query: 750 SN 751 +N Sbjct: 817 NN 818 Score = 34.3 bits (77), Expect = 0.63 Identities = 13/30 (43%), Positives = 24/30 (80%) Query: 994 VWVIILAVLAGLLLLAVLVFVMYRMGFFKR 1023 +++ +L+ + GLLLL ++ V+Y++GFFKR Sbjct: 1006 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKR 1035 >gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] Length = 1170 Score = 121 bits (304), Expect = 3e-27 Identities = 152/602 (25%), Positives = 254/602 (42%), Gaps = 64/602 (10%) Query: 175 QDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKY 234 QD+ + G S D ++ V+ G G+ W G + ++ + + + Sbjct: 340 QDLTSFNMELSSSGISADLSRGHAVV-GAVGAKDWAGGFL-----DLKADLQDDTF---I 390 Query: 235 NNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYD----GKN 290 N+ T +A YLGY+V + SG PR +G V ++ G + Sbjct: 391 GNEPLTPEVRA----GYLGYTVTWLP-SRQKTSLLASGAPRYQH-MGRVLLFQEPQGGGH 444 Query: 291 MSSLYNFTGEQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSL 349 S + G Q+ +YFG + D++ D ++ IGAPLF Q G+V + Sbjct: 445 WSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGE------QRGGRVFIYQ 498 Query: 350 QRASGDFQTTKLNGFEVF--ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFN 407 +R G + ++L G + RFG AI L D++ DG D+A+ AP +++G VYIFN Sbjct: 499 RRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFN 555 Query: 408 GRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRA 467 GR GL+ PSQ +EG + FG S+ G D++ +G D+ VGA + I+ + Sbjct: 556 GRHGGLSPQPSQRIEGTQVLSGI-QWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSS 612 Query: 468 RPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVEL 527 RPV+ + + P+ + CS + N+ C + K ++P+ V Sbjct: 613 RPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQI--KSLIPQFQGRLVAN 670 Query: 528 LLDKLKQKG--AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPI 585 L L+ G RR LF R H I+ M C + + +D ++PI Sbjct: 671 LTYTLQLDGHRTRRRGLFPGGR---HELRRNIAVTTSMSCTDFSFHF--PVCVQDLISPI 725 Query: 586 TIFMEYRL--------DYRTAADTTGLQPILNQFTPANISRQAHILLD--CGEDNVCKPK 635 + + + L D R A + PIL P+ S I + CGED C+ Sbjct: 726 NVSLNFSLWEEEGTPRDQR--AQGKDIPPILR---PSLHSETWEIPFEKNCGEDKKCEAN 780 Query: 636 LEVSVD-SDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGV-VRNNEAL 693 L VS + + + + L++ + N E AY +L + P F V + + Sbjct: 781 LRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQ 840 Query: 694 ARLSCAFKTENQ---TRQVVCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQS 749 +SC E +R + C++ +P+ KAG + + F+ S SV+ + Sbjct: 841 IPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTC 900 Query: 750 SN 751 +N Sbjct: 901 NN 902 Score = 34.3 bits (77), Expect = 0.63 Identities = 13/30 (43%), Positives = 24/30 (80%) Query: 994 VWVIILAVLAGLLLLAVLVFVMYRMGFFKR 1023 +++ +L+ + GLLLL ++ V+Y++GFFKR Sbjct: 1090 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKR 1119 >gi|29171717 glycosylphosphatidylinositol specific phospholipase D1 isoform 1 precursor [Homo sapiens] Length = 840 Score = 61.6 bits (148), Expect = 4e-09 Identities = 55/221 (24%), Positives = 104/221 (47%), Gaps = 29/221 (13%) Query: 253 GYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYF------ 306 G +V + D + + R RT+ G +S + +A+YF Sbjct: 326 GVFFSVNSWTPDSMSFIYKALERNIRTM----FIGGSQLSQKH--VSSPLASYFLSFPYA 379 Query: 307 --GFSVAATDINGDDYADVFIGAPLFMDRG--SDGKLQEVGQVSVSLQRASGDFQTTK-- 360 G+++ + D+N D + D+ +GAP + G G++ + + L D Sbjct: 380 RLGWAMTSADLNQDGHGDLVVGAPGYSRPGHIHIGRVYLIYGNDLGLPPVDLDLDKEAHR 439 Query: 361 -LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDK---KGIVYI-FNGRSTGLNA 415 L GF+ RFGSA+A L D + DG D+A+ AP G ++ KG VY+ F + G+++ Sbjct: 440 ILEGFQPSGRFGSALAVL-DFNVDGVPDLAVGAPSVGSEQLTYKGAVYVYFGSKQGGMSS 498 Query: 416 VPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGA 456 P+ + + + + + G+++ A D++ + PDL++G+ Sbjct: 499 SPNITI----SCQDIYCNLGWTLL-AADVNGDSEPDLVIGS 534 Score = 55.1 bits (131), Expect = 3e-07 Identities = 56/218 (25%), Positives = 91/218 (41%), Gaps = 27/218 (12%) Query: 247 FDDSYLGYSVAVGDFNGDGIDDFVSGVPRAART----LGMVYIYDGKNM----------- 291 F + LG+++ D N DG D V G P +R +G VY+ G ++ Sbjct: 376 FPYARLGWAMTSADLNQDGHGDLVVGAPGYSRPGHIHIGRVYLIYGNDLGLPPVDLDLDK 435 Query: 292 SSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQR 351 + G Q + FG ++A D N D D+ +GAP GS+ +L G V V Sbjct: 436 EAHRILEGFQPSGRFGSALAVLDFNVDGVPDLAVGAP---SVGSE-QLTYKGAVYVYFGS 491 Query: 352 ASGDFQTT---KLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPY--GGEDKKGIVYIF 406 G ++ ++ +++ G + D++ D D+ I +P+ GG +KGIV F Sbjct: 492 KQGGMSSSPNITISCQDIYCNLGWTLL-AADVNGDSEPDLVIGSPFAPGGGKQKGIVAAF 550 Query: 407 NGRSTGLNAVPSQILEGQWAARSMPPS--FGYSMKGAT 442 + + + W R FGYS+ G T Sbjct: 551 YSGPSLSDKEKLNVEAANWTVRGEEDFSWFGYSLHGVT 588 Score = 55.1 bits (131), Expect = 3e-07 Identities = 48/159 (30%), Positives = 77/159 (48%), Gaps = 32/159 (20%) Query: 278 RTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDI--NGDDYADVFIGAPLFMDRGS 335 ++LG VY Y N S + +G++ G S+++ + NG + +GAP + D Sbjct: 619 KSLGRVYGYFPPNGQSWFTISGDKAMGKLGTSLSSGHVLMNGTLKQVLLVGAPTYDD--- 675 Query: 336 DGKLQEVGQVSVSLQRA--------SGDFQTTKLNGFEV---FARFGSAIAPLGDLDQDG 384 + +V ++V+L + + D Q L+ F F+RFG + L DLD DG Sbjct: 676 ---VSKVAFLTVTLHQGGATRMYALTSDAQPLLLSTFSGDRRFSRFGGVLH-LSDLDDDG 731 Query: 385 FNDIAIAAP----------YGGEDKKGIVYIFNGRSTGL 413 ++I +AAP GGED G VY++NG+ T L Sbjct: 732 LDEIIMAAPLRIADVTSGLIGGED--GRVYVYNGKETTL 768 Score = 48.9 bits (115), Expect = 2e-05 Identities = 34/99 (34%), Positives = 45/99 (45%), Gaps = 9/99 (9%) Query: 239 ATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTL----GMVYIYDGKN---M 291 A R + G ++AV DFN DG+ D G P G VY+Y G M Sbjct: 437 AHRILEGFQPSGRFGSALAVLDFNVDGVPDLAVGAPSVGSEQLTYKGAVYVYFGSKQGGM 496 Query: 292 SSLYNFTGEQMAAY--FGFSVAATDINGDDYADVFIGAP 328 SS N T Y G+++ A D+NGD D+ IG+P Sbjct: 497 SSSPNITISCQDIYCNLGWTLLAADVNGDSEPDLVIGSP 535 >gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo sapiens] Length = 462 Score = 50.4 bits (119), Expect = 9e-06 Identities = 92/454 (20%), Positives = 168/454 (37%), Gaps = 56/454 (12%) Query: 625 DCGEDNVCKPKLEVSVD-SDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADF 683 +CG D++C+ L +S K + +G + L V N GE +Y + S P + Sbjct: 19 NCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGLSY 78 Query: 684 IGVVRNNEA----LARLSC--AFKTENQTRQVVCDLGNPM-KAGTQLLAGLRFSVHQQSE 736 V + L+C A T C + + + + G Q+ F V ++ Sbjct: 79 RYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQITFLATFDVSPKAV 138 Query: 737 MDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENP 796 + + + S N + S + +++L V AV V S F N+ Sbjct: 139 LGDRLLLTANVSSENNTPRTSKT-TFQLELPVKYAVYT--VVSSHEQFTKYLNFS----- 190 Query: 797 ETEEDVGPVVQHIYELRNNGPSSFS----------KAMLHLQWPYKYNNNTL-------- 838 E+EE V H Y+ ++ ++ P + N + Sbjct: 191 ESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQEAVWMDVEVSH 250 Query: 839 -------LYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRD 891 +++LH + ++ M + + + L +N ++ E+ Sbjct: 251 PQVPKDCMWLLH-ECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCSSEKIAPPASDF 309 Query: 892 LALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLL---WTETFMNKENQNHSY 948 LA + + L C +A CL+ C V + +K L W + K+ Sbjct: 310 LAHIQKN-PVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKK-----V 363 Query: 949 SLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLL 1008 S+ S A Y LP ++ + T ++ + P +I+ + + GLLLL Sbjct: 364 SVVSVAEITFDTSVYSQLPGQE----AFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLL 419 Query: 1009 AVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENG 1042 A++ V+Y++GFFKR E+ Q+ P ENG Sbjct: 420 ALITAVLYKVGFFKRQYKEMMEEANGQIAP-ENG 452 >gi|31881770 ADAM metallopeptidase domain 30 preproprotein [Homo sapiens] Length = 790 Score = 31.6 bits (70), Expect = 4.1 Identities = 13/47 (27%), Positives = 26/47 (55%) Query: 984 GIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEE 1030 G+ +P +WV+ + + +LL+ +VFV +R ++P QE+ Sbjct: 676 GLLRGAIPSSIWVVSIIMFRLILLILSVVFVFFRQVIGNHLKPKQEK 722 >gi|8393638 F11 receptor precursor [Homo sapiens] Length = 299 Score = 31.2 bits (69), Expect = 5.3 Identities = 20/54 (37%), Positives = 26/54 (48%), Gaps = 3/54 (5%) Query: 994 VWVIILAVLAGLLLLAVLVF---VMYRMGFFKRVRPPQEEQEREQLQPHENGEG 1044 V VI+ AVL L+LL +LVF Y G F R + ++ QP EG Sbjct: 236 VGVIVAAVLVTLILLGILVFGIWFAYSRGHFDRTKKGTSSKKVIYSQPSARSEG 289 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.137 0.410 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 40,652,132 Number of Sequences: 37866 Number of extensions: 1890806 Number of successful extensions: 4033 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 30 Number of HSP's successfully gapped in prelim test: 2 Number of HSP's that attempted gapping in prelim test: 3640 Number of HSP's gapped (non-prelim): 67 length of query: 1048 length of database: 18,247,518 effective HSP length: 113 effective length of query: 935 effective length of database: 13,968,660 effective search space: 13060697100 effective search space used: 13060697100 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.