Guide to the Human Genome
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Search of human proteins with 4504763

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
         (1048 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]       2117   0.0  
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]     2019   0.0  
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]               1992   0.0  
gi|49170034 integrin, alpha 8 [Homo sapiens]                          970   0.0  
gi|56237029 integrin alpha 5 precursor [Homo sapiens]                 922   0.0  
gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]            630   e-180
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [...   335   2e-91
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [...   333   4e-91
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]      319   1e-86
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]      314   3e-85
gi|67191027 integrin alpha 4 precursor [Homo sapiens]                 296   9e-80
gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]                276   6e-74
gi|52485941 integrin, alpha 9 precursor [Homo sapiens]                270   5e-72
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]        270   5e-72
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]        267   3e-71
gi|31657142 integrin, alpha 1 precursor [Homo sapiens]                211   3e-54
gi|116295258 integrin alpha 2 precursor [Homo sapiens]                199   9e-51
gi|52485853 integrin, alpha 11 precursor [Homo sapiens]               171   3e-42
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]       168   2e-41
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]      167   6e-41
gi|34452173 integrin alpha X precursor [Homo sapiens]                 167   6e-41
gi|148728188 integrin, alpha E precursor [Homo sapiens]               159   1e-38
gi|38569398 integrin, alpha 10 precursor [Homo sapiens]               149   1e-35
gi|62548866 integrin, alpha D precursor [Homo sapiens]                147   7e-35
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]      123   1e-27
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]      121   3e-27
gi|29171717 glycosylphosphatidylinositol specific phospholipase ...    62   4e-09
gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ...    50   9e-06
gi|31881770 ADAM metallopeptidase domain 30 preproprotein [Homo ...    32   4.1  
gi|8393638 F11 receptor precursor [Homo sapiens]                       31   5.3  

>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
          Length = 1048

 Score = 2117 bits (5484), Expect = 0.0
 Identities = 1048/1048 (100%), Positives = 1048/1048 (100%)

Query: 1    MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSA 60
            MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSA
Sbjct: 1    MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSA 60

Query: 61   SSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKS 120
            SSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKS
Sbjct: 61   SSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKS 120

Query: 121  HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDAD 180
            HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDAD
Sbjct: 121  HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDAD 180

Query: 181  GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLAT 240
            GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLAT
Sbjct: 181  GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLAT 240

Query: 241  RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE 300
            RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE
Sbjct: 241  RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE 300

Query: 301  QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK 360
            QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK
Sbjct: 301  QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK 360

Query: 361  LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQI 420
            LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQI
Sbjct: 361  LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQI 420

Query: 421  LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY 480
            LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY
Sbjct: 421  LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY 480

Query: 481  PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRR 540
            PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRR
Sbjct: 481  PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRR 540

Query: 541  ALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAAD 600
            ALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAAD
Sbjct: 541  ALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAAD 600

Query: 601  TTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVK 660
            TTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVK
Sbjct: 601  TTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVK 660

Query: 661  AQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAG 720
            AQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAG
Sbjct: 661  AQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAG 720

Query: 721  TQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSP 780
            TQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSP
Sbjct: 721  TQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSP 780

Query: 781  DHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLY 840
            DHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLY
Sbjct: 781  DHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLY 840

Query: 841  ILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIH 900
            ILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIH
Sbjct: 841  ILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIH 900

Query: 901  TLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIE 960
            TLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIE
Sbjct: 901  TLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIE 960

Query: 961  FPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGF 1020
            FPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGF
Sbjct: 961  FPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGF 1020

Query: 1021 FKRVRPPQEEQEREQLQPHENGEGNSET 1048
            FKRVRPPQEEQEREQLQPHENGEGNSET
Sbjct: 1021 FKRVRPPQEEQEREQLQPHENGEGNSET 1048


>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
          Length = 1012

 Score = 2019 bits (5231), Expect = 0.0
 Identities = 1011/1048 (96%), Positives = 1012/1048 (96%), Gaps = 36/1048 (3%)

Query: 1    MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSA 60
            MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSA
Sbjct: 1    MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSA 60

Query: 61   SSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKS 120
            SSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKS
Sbjct: 61   SSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKS 120

Query: 121  HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDAD 180
            HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRS+     
Sbjct: 121  HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSR----- 175

Query: 181  GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLAT 240
                                           QLISDQVAEIVSKYDPNVYSIKYNNQLAT
Sbjct: 176  -------------------------------QLISDQVAEIVSKYDPNVYSIKYNNQLAT 204

Query: 241  RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE 300
            RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE
Sbjct: 205  RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE 264

Query: 301  QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK 360
            QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK
Sbjct: 265  QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK 324

Query: 361  LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQI 420
            LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQI
Sbjct: 325  LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQI 384

Query: 421  LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY 480
            LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY
Sbjct: 385  LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY 444

Query: 481  PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRR 540
            PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRR
Sbjct: 445  PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRR 504

Query: 541  ALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAAD 600
            ALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAAD
Sbjct: 505  ALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAAD 564

Query: 601  TTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVK 660
            TTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVK
Sbjct: 565  TTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVK 624

Query: 661  AQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAG 720
            AQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAG
Sbjct: 625  AQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAG 684

Query: 721  TQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSP 780
            TQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSP
Sbjct: 685  TQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSP 744

Query: 781  DHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLY 840
            DHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLY
Sbjct: 745  DHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLY 804

Query: 841  ILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIH 900
            ILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIH
Sbjct: 805  ILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIH 864

Query: 901  TLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIE 960
            TLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIE
Sbjct: 865  TLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIE 924

Query: 961  FPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGF 1020
            FPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGF
Sbjct: 925  FPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGF 984

Query: 1021 FKRVRPPQEEQEREQLQPHENGEGNSET 1048
            FKRVRPPQEEQEREQLQPHENGEGNSET
Sbjct: 985  FKRVRPPQEEQEREQLQPHENGEGNSET 1012


>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
          Length = 1002

 Score = 1992 bits (5160), Expect = 0.0
 Identities = 986/986 (100%), Positives = 986/986 (100%)

Query: 63   RMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQ 122
            RMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQ
Sbjct: 17   RMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQ 76

Query: 123  WFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQ 182
            WFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQ
Sbjct: 77   WFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQ 136

Query: 183  GFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRT 242
            GFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRT
Sbjct: 137  GFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRT 196

Query: 243  AQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQM 302
            AQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQM
Sbjct: 197  AQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQM 256

Query: 303  AAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLN 362
            AAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLN
Sbjct: 257  AAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLN 316

Query: 363  GFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILE 422
            GFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILE
Sbjct: 317  GFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILE 376

Query: 423  GQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPS 482
            GQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPS
Sbjct: 377  GQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPS 436

Query: 483  ILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRAL 542
            ILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRAL
Sbjct: 437  ILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRAL 496

Query: 543  FLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTT 602
            FLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTT
Sbjct: 497  FLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTT 556

Query: 603  GLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQ 662
            GLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQ
Sbjct: 557  GLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQ 616

Query: 663  NQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQ 722
            NQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQ
Sbjct: 617  NQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQ 676

Query: 723  LLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDH 782
            LLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDH
Sbjct: 677  LLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDH 736

Query: 783  IFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYIL 842
            IFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYIL
Sbjct: 737  IFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYIL 796

Query: 843  HYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTL 902
            HYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTL
Sbjct: 797  HYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTL 856

Query: 903  GCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFP 962
            GCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFP
Sbjct: 857  GCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFP 916

Query: 963  YKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFK 1022
            YKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFK
Sbjct: 917  YKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFK 976

Query: 1023 RVRPPQEEQEREQLQPHENGEGNSET 1048
            RVRPPQEEQEREQLQPHENGEGNSET
Sbjct: 977  RVRPPQEEQEREQLQPHENGEGNSET 1002


>gi|49170034 integrin, alpha 8 [Homo sapiens]
          Length = 1063

 Score =  970 bits (2507), Expect = 0.0
 Identities = 500/1052 (47%), Positives = 691/1052 (65%), Gaps = 31/1052 (2%)

Query: 12   GPRG--LPLLLS--------GLLL--PLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPS 59
            GPRG   PL+          G+LL  P C+AFNLDV+    YSGP+GSYFG+AVDF +P 
Sbjct: 8    GPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPD 67

Query: 60   ASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSS--TRRCQPIEFDATGNRDYAKD---D 114
            A +   +LVGAPKANT+QP IVEGG V  C W +  + +C+ I FD T NR    +   +
Sbjct: 68   ARTAS-VLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGTKE 126

Query: 115  PLEFKSHQWFGASVRSKQDKILACAPLYHWRT-EMKQEREPVGTCF--LQDGTKTVEYAP 171
            P+EFKS+QWFGA+V++ + K++ACAPLYHWRT +   E++PVGTC+  +Q+ +   E++P
Sbjct: 127  PIEFKSNQWFGATVKAHKGKVVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSAYAEFSP 186

Query: 172  CRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYS 231
            CR+ + D +GQG+CQ GFS+DF K   +++GGPGSFYWQGQ+I+  VA+I++ Y      
Sbjct: 187  CRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDIL 246

Query: 232  IKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNM 291
             K   +  T  A A +DDSYLGYSVA G+F GD   + V+G+PR A+  G V I +  +M
Sbjct: 247  RKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINSTDM 306

Query: 292  SSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQR 351
            + + NFTGEQMA+YFG++V  +D+N D   DV +GAPLFM+R  +   +EVGQ+ + LQ 
Sbjct: 307  TFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQIYLYLQV 366

Query: 352  ASGDFQTTK-LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS 410
            +S  F+  + L G E F RFGSA+A LGDL+QDG+NDIAI  P+ G+D++G V I+NG  
Sbjct: 367  SSLLFRDPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNK 426

Query: 411  TGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPV 470
             GLN  PSQ+L+G WA+ ++P  FG++++G +DIDKN YPDLIVGAFG  +  +YRARPV
Sbjct: 427  DGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPV 486

Query: 471  ITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD 530
            +TV+A L ++P I+N +NKTC +P +    +CF++R C    G+ +    +    E+ LD
Sbjct: 487  VTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIA-NTIVLMAEVQLD 545

Query: 531  KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFME 590
             LKQKGAI+R LFL +        + I R    QC++ I YLRDE+EFRDKL+PI I + 
Sbjct: 546  SLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLN 605

Query: 591  YRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIG 650
            Y LD  T  +   ++PILN +    +S QAHIL+DCGEDN+C P L++S   D+ ++ IG
Sbjct: 606  YSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKHQVIIG 665

Query: 651  DDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVV 710
            D+N L LI+ A+N+GEGAYEAEL V IP +AD++G+ RNN+    LSC +K EN TR VV
Sbjct: 666  DENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENVTRMVV 725

Query: 711  CDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLA 770
            CDLGNPM +GT    GLRF+V +  + + S+ FDLQI+SSN  +  S  VS ++++  +A
Sbjct: 726  CDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQINITAVA 785

Query: 771  AVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWP 830
             VEIRGVS P  I LPI NWE +E P  EE+VGP+V+HIYEL N GPS+ S  +L + WP
Sbjct: 786  QVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTILEVGWP 845

Query: 831  YKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIK-ISSLQTTEKNDTVAGQGERDHLITK 889
            +   +  LLYI H    GP+ C  +  INP  IK  +S + T +           HL+ K
Sbjct: 846  FSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRK 905

Query: 890  RDLALSE----GDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQN 945
            RD+ + E         L C   +CL+I C VGRL+ G+SA+L V+S LW  TF+ ++N  
Sbjct: 906  RDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKND- 964

Query: 946  HSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGL 1005
              Y+L S  SF V + PY + P +    S  + T+V W        +P+WVIILA+L GL
Sbjct: 965  -PYALASLVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLWVIILAILLGL 1023

Query: 1006 LLLAVLVFVMYRMGFFKRVRPPQEEQ-EREQL 1036
            L+LA+L   +++ GFF R RPPQE+  +REQL
Sbjct: 1024 LVLAILTLALWKCGFFDRARPPQEDMTDREQL 1055


>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
          Length = 1049

 Score =  922 bits (2383), Expect = 0.0
 Identities = 485/1049 (46%), Positives = 676/1049 (64%), Gaps = 37/1049 (3%)

Query: 8    RLRLGPRGLPLLLSGLLL-----PLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASS 62
            +LR GPR  P LL  LLL     P    FNLD ++PA  SGP GS+FGF+V+F+ P    
Sbjct: 14   QLRWGPRRRPPLLPLLLLLLPPPPRVGGFNLDAEAPAVLSGPPGSFFGFSVEFYRPGTDG 73

Query: 63   RMFLLVGAPKANTTQPGIVEGGQVLKCDW-SSTRRCQPIEFDATGNR-------DYAKDD 114
             + +LVGAPKANT+QPG+++GG V  C W +S  +C PIEFD+ G+R           ++
Sbjct: 74   -VSVLVGAPKANTSQPGVLQGGAVYLCPWGASPTQCTPIEFDSKGSRLLESSLSSSEGEE 132

Query: 115  PLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDG--TKTVEYAPC 172
            P+E+KS QWFGA+VR+    ILACAPLY WRTE +   +PVGTC+L     T+ +EYAPC
Sbjct: 133  PVEYKSLQWFGATVRAHGSSILACAPLYSWRTEKEPLSDPVGTCYLSTDNFTRILEYAPC 192

Query: 173  RSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSI 232
            RS    A GQG+CQGGFS +FTK  RV+LGGPGS++WQGQ++S    +I   Y P     
Sbjct: 193  RSDFSWAAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQIAESYYPEYLIN 252

Query: 233  KYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMS 292
                QL TR A +I+DDSYLGYSVAVG+F+GD  +DFV+GVP+   T G V I +G ++ 
Sbjct: 253  LVQGQLQTRQASSIYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVTILNGSDIR 312

Query: 293  SLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRA 352
            SLYNF+GEQMA+YFG++VAATD+NGD   D+ +GAPL MDR  DG+ QEVG+V V LQ  
Sbjct: 313  SLYNFSGEQMASYFGYAVAATDVNGDGLDDLLVGAPLLMDRTPDGRPQEVGRVYVYLQHP 372

Query: 353  SG--DFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS 410
            +G     T  L G + F RFGS++ PLGDLDQDG+ND+AI AP+GGE ++G+V++F G  
Sbjct: 373  AGIEPTPTLTLTGHDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFPGGP 432

Query: 411  TGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPV 470
             GL + PSQ+L+  WAA   P  FG +++G  D+D NGYPDLIVG+FGVD+A++YR RP+
Sbjct: 433  GGLGSKPSQVLQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRPI 492

Query: 471  ITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD 530
            ++ +A L ++P++ N + ++CSL G    V+C N+ FCL A GK V    + F VEL LD
Sbjct: 493  VSASASLTIFPAMFNPEERSCSLEGN--PVACINLSFCLNASGKHVAD-SIGFTVELQLD 549

Query: 531  KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFME 590
              KQKG +RRALFL SR  + ++ + I  G    C E+  YLR+ESEFRDKL+PI I + 
Sbjct: 550  WQKQKGGVRRALFLASRQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHIALN 609

Query: 591  YRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIG 650
            + LD +   D+ GL+P L+  + + I  +A ILLDCGEDN+C P L++ V  +Q  +Y+G
Sbjct: 610  FSLDPQAPVDSHGLRPALHYQSKSRIEDKAQILLDCGEDNICVPDLQLEVFGEQNHVYLG 669

Query: 651  DDNPLTLIVKAQNQGE-GAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQV 709
            D N L L   AQN GE GAYEAEL V+ P +A++ G+VR+    + LSC +   NQ+R +
Sbjct: 670  DKNALNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGLVRHPGNFSSLSCDYFAVNQSRLL 729

Query: 710  VCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVL 769
            VCDLGNPMKAG  L  GLRF+V    +   +++FD QI S NL +  S VVS ++ +   
Sbjct: 730  VCDLGNPMKAGASLWGGLRFTVPHLRDTKKTIQFDFQILSKNLNNSQSDVVSFRLSVEAQ 789

Query: 770  AAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQW 829
            A V + GVS P+ +  P+ +W  ++ P+ EED+GP V H+YEL N GPSS S+ +L L  
Sbjct: 790  AQVTLNGVSKPEAVLFPVSDWHPRDQPQKEEDLGPAVHHVYELINQGPSSISQGVLELSC 849

Query: 830  PYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITK 889
            P       LLY+    + G +NCT++  INP  +++      +   ++  Q +R+     
Sbjct: 850  PQALEGQQLLYVTR--VTG-LNCTTNHPINPKGLEL------DPEGSLHHQQKRE--APS 898

Query: 890  RDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYS 949
            R  A S   I  L C  A+C ++ C++G L + +S  L +   +W +TF+ +E+Q   +S
Sbjct: 899  RSSASSGPQI--LKCPEAECFRLRCELGPLHQQESQSLQLHFRVWAKTFLQREHQ--PFS 954

Query: 950  LKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLA 1009
            L+  A +  ++ PY+ LP +       V T V W        VP+W+IILA+L GLLLL 
Sbjct: 955  LQCEAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVPLWIIILAILFGLLLLG 1014

Query: 1010 VLVFVMYRMGFFKRVRPPQEEQEREQLQP 1038
            +L++++Y++GFFKR  P     E+ QL+P
Sbjct: 1015 LLIYILYKLGFFKRSLPYGTAMEKAQLKP 1043


>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
          Length = 1039

 Score =  630 bits (1624), Expect = e-180
 Identities = 399/1045 (38%), Positives = 569/1045 (54%), Gaps = 54/1045 (5%)

Query: 18   LLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQ 77
            LLL     P   A NLD      Y+GP GS FGF++DF   S   R+ ++VGAP+  T  
Sbjct: 19   LLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDS-HGRVAIVVGAPR--TLG 75

Query: 78   PGIVEGGQVLKCDWSSTR-RCQPIEFDATGNRDYAKDDPLE-FKSHQWFGASVRSKQDKI 135
            P   E G V  C W +   +C  + FD            L+ FK+ Q  GASV S  D I
Sbjct: 76   PSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVI 135

Query: 136  LACAPLYHWRTEMKQE---REPVGTCFLQ--DGTKTVEYAPCRSQDID--------ADGQ 182
            +ACAP  HW    K E   + PVG+CFL   +  +  EY+PCR   +         +  +
Sbjct: 136  VACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDK 195

Query: 183  GFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQ-LATR 241
             +C+ GFS   T+A  ++LG PG +Y+ G L    VA+I S Y P +     ++Q L+  
Sbjct: 196  RYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFD 255

Query: 242  TAQAIFDDSYLGYSVAVGDFNGD-GIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE 300
            ++   + D Y GYSVAVG+F+GD    ++V G P  + TLG V I D      L+   GE
Sbjct: 256  SSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSY-YQRLHRLRGE 314

Query: 301  QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQ----RASGDF 356
            QMA+YFG SVA TD+NGD   D+ +GAPL+M+  +D KL EVG+V + LQ     A G  
Sbjct: 315  QMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGA- 373

Query: 357  QTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAV 416
             +  L G +++ RFGSAIAPLGDLD+DG+NDIA+AAPYGG   +G V +F G+S GL + 
Sbjct: 374  PSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSR 433

Query: 417  PSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAG 476
            PSQ+L+  +   S   +FG+S++GA DID NGYPDLIVGA+G ++  +YRA+PV+  +  
Sbjct: 434  PSQVLDSPFPTGS---AFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQ 490

Query: 477  LEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKG 536
            L V  S LN   K+C LP T   VSCFN++ C+ A G  + P+KL+   EL LD+ K + 
Sbjct: 491  LLVQDS-LNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNI-PQKLSLNAELQLDRQKPRQ 548

Query: 537  AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYR 596
              RR L L S+    + N+ +       C   +A+LRDE++FRDKL+PI + +   L   
Sbjct: 549  G-RRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPT 607

Query: 597  TAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLT 656
             A    G+ P +      ++  Q  I+LDCGED+VC P+L+++       + +G DN L 
Sbjct: 608  EA----GMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLE 663

Query: 657  LIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNP 716
            L + A N+GEGAYEAEL V +P  A ++  + N E   RL C  K EN+TR V+C+LGNP
Sbjct: 664  LQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNP 723

Query: 717  MKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRG 776
            MK   Q+   +  SV    E   SV F LQI+S N  +  S +V   V +   A VE+RG
Sbjct: 724  MKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRG 783

Query: 777  VSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNN 836
             S P  + +     E ++N  + +  GP V+H YEL NNGP + +   L +  P +   +
Sbjct: 784  NSFPASLVVAAEEGEREQN--SLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPS 841

Query: 837  TLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSE 896
             LLYIL     G + C     +NPL++    L     +       +RD    +R + L E
Sbjct: 842  DLLYILDIQPQGGLQCFPQPPVNPLKVD-WGLPIPSPSPIHPAHHKRD----RRQIFLPE 896

Query: 897  -------GDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYS 949
                    D   + C  A C  + C +  + RG+ A++ V + LW  +   +      + 
Sbjct: 897  PEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLD--QFV 954

Query: 950  LKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLA 1009
            L+S A FNV   PY   P+        V T +   ++     +P+W +++ VL GLLLL 
Sbjct: 955  LQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALE--ERAIPIWWVLVGVLGGLLLLT 1012

Query: 1010 VLVFVMYRMGFFKRVRPPQEEQERE 1034
            +LV  M+++GFFKR RPP EE + E
Sbjct: 1013 ILVLAMWKVGFFKRNRPPLEEDDEE 1037


>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo
            sapiens]
          Length = 1091

 Score =  335 bits (858), Expect = 2e-91
 Identities = 303/1077 (28%), Positives = 508/1077 (47%), Gaps = 112/1077 (10%)

Query: 19   LLSGLLLPLCRAFNLDV--DSPAEYSGPEGSYFGFAVDF-FVPSASSRMFLLVGAPKANT 75
            L +GLL  L  AFNLD   D+     G  GS FGF++   +      +  LLVGAP+A  
Sbjct: 12   LSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEA 71

Query: 76   T--QPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQD 133
               Q     GG +  CD ++   C  IEFD         D   E K  QW G +V+S+  
Sbjct: 72   LPLQRANRTGG-LYSCDITARGPCTRIEFDNDA------DPTSESKEDQWMGVTVQSQGP 124

Query: 134  --KILACAPLYHWRTEM--KQE-REPVGTCF-------LQDGTKTVEYAPCRSQDIDADG 181
              K++ CA  Y  R  +  KQE R+  G C+       ++D     +++ C  +    + 
Sbjct: 125  GGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEK 184

Query: 182  QGFCQGGFSIDFTKADR-VLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSI-KYNNQLA 239
             G CQ G +  FTK    ++ G PG++ W+G +  +Q       +D N++    Y     
Sbjct: 185  FGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTF--FDMNIFEDGPYEVGGE 242

Query: 240  TRTAQAIFD---DSYLGYSVAVGD--FNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSL 294
            T   +++     +SYLG+S+  G    + D I  FVSG PRA  +  +V +      + L
Sbjct: 243  TEHDESLVPVPANSYLGFSLDSGKGIVSKDEIT-FVSGAPRANHSGAVVLLKRDMKSAHL 301

Query: 295  ---YNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQR 351
               + F GE +A+ FG+ VA  D+N D + D+ IGAP + DR  DG++     V ++ Q 
Sbjct: 302  LPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDR--DGEVGGAVYVYMNQQG 359

Query: 352  ASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRST 411
               + +  +LNG +  + FG A+  +GD++QDG+ DIA+ APY   D  G V+I++G + 
Sbjct: 360  RWNNVKPIRLNGTKD-SMFGIAVKNIGDINQDGYPDIAVGAPY---DDLGKVFIYHGSAN 415

Query: 412  GLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVI 471
            G+N  P+Q+L+G      + P FGYS+ G  D+D+N YPD+ VG+   D   ++R+RPVI
Sbjct: 416  GINTKPTQVLKG------ISPYFGYSIAGNMDLDRNSYPDVAVGSLS-DSVTIFRSRPVI 468

Query: 472  TVNAGLEVYPSILNQDNKT-CSLPGTALKVSCFNVRFCLK--ADGKGVLPRKLNFQVELL 528
             +   + V P+ ++   KT C  P       C  V+ C +  A+  G  P  ++    L 
Sbjct: 469  NIQKTITVTPNRIDLRQKTACGAPSGI----CLQVKSCFEYTANPAGYNP-SISIVGTLE 523

Query: 529  LDKLKQK-GAIRRALFLYSRS-PSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPIT 586
             +K ++K G   R  F    S P +++ +T+ R     C E   +L+D    RDKL PI 
Sbjct: 524  AEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDN--IRDKLRPIP 581

Query: 587  IFMEYRLDY----RTAADTTGLQPILNQFTPANISRQAHILLD-CGEDNVCKPKLEVSV- 640
            I     +      R       + PILN   P       H L + CG+DNVC   L++   
Sbjct: 582  ITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYK 641

Query: 641  ----DSDQKK------------IYIGDDNPLTLIVKAQNQ----------GEGAYEAELI 674
                + +Q K            + + D   + L +   N           G+ A+EA+LI
Sbjct: 642  FCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLI 701

Query: 675  VSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQ 734
             + P    +    R   A      +        Q  C+LGNP K  + +   L  S  + 
Sbjct: 702  ATFPDTLTY-SAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEV 760

Query: 735  SEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKE 794
            +     +  +L++++++  D ++P+ + K  + +   + + GV+ P  ++        ++
Sbjct: 761  TFDTPDLDINLKLETTSNQDNLAPITA-KAKVVIELLLSVSGVAKPSQVYFG-GTVVGEQ 818

Query: 795  NPETEEDVGPVVQHIYELRNNGP--SSFSKAMLHLQWPYKYNNNT-LLYILHYDIDG--P 849
              ++E++VG ++++ + + N G   ++   A L++QWP + +N   LLY++  +  G   
Sbjct: 819  AMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEK 878

Query: 850  MNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGV-AQ 908
            + C    EIN L +  S     ++  T     E+     ++    +E    TL C V   
Sbjct: 879  VTCEPQKEINSLNLTESHNSRKKREIT-----EKQIDDNRKFSLFAERKYQTLNCSVNVN 933

Query: 909  CLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPI 968
            C+ I C +  LD   S IL  +S LW  TF+ + ++ +   +   A  +V     +N+ +
Sbjct: 934  CVNIRCPLRGLDSKASLIL--RSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAA-ENIRL 990

Query: 969  EDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVR 1025
             +      VT   +  +      VP W+I++A+LAG+L+LA+LVF++++ GFFKR R
Sbjct: 991  PNAGTQVRVTVFPSKTVAQYS-GVPWWIILVAILAGILMLALLVFILWKCGFFKRSR 1046


>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo
            sapiens]
          Length = 1073

 Score =  333 bits (855), Expect = 4e-91
 Identities = 302/1075 (28%), Positives = 507/1075 (47%), Gaps = 112/1075 (10%)

Query: 19   LLSGLLLPLCRAFNLDV--DSPAEYSGPEGSYFGFAVDF-FVPSASSRMFLLVGAPKANT 75
            L +GLL  L  AFNLD   D+     G  GS FGF++   +      +  LLVGAP+A  
Sbjct: 12   LSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEA 71

Query: 76   T--QPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQD 133
               Q     GG +  CD ++   C  IEFD         D   E K  QW G +V+S+  
Sbjct: 72   LPLQRANRTGG-LYSCDITARGPCTRIEFDNDA------DPTSESKEDQWMGVTVQSQGP 124

Query: 134  --KILACAPLYHWRTEM--KQE-REPVGTCF-------LQDGTKTVEYAPCRSQDIDADG 181
              K++ CA  Y  R  +  KQE R+  G C+       ++D     +++ C  +    + 
Sbjct: 125  GGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEK 184

Query: 182  QGFCQGGFSIDFTKADR-VLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSI-KYNNQLA 239
             G CQ G +  FTK    ++ G PG++ W+G +  +Q       +D N++    Y     
Sbjct: 185  FGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTF--FDMNIFEDGPYEVGGE 242

Query: 240  TRTAQAIFD---DSYLGYSVAVGD--FNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSL 294
            T   +++     +SYLG+S+  G    + D I  FVSG PRA  +  +V +      + L
Sbjct: 243  TEHDESLVPVPANSYLGFSLDSGKGIVSKDEIT-FVSGAPRANHSGAVVLLKRDMKSAHL 301

Query: 295  ---YNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQR 351
               + F GE +A+ FG+ VA  D+N D + D+ IGAP + DR  DG++     V ++ Q 
Sbjct: 302  LPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDR--DGEVGGAVYVYMNQQG 359

Query: 352  ASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRST 411
               + +  +LNG +  + FG A+  +GD++QDG+ DIA+ APY   D  G V+I++G + 
Sbjct: 360  RWNNVKPIRLNGTKD-SMFGIAVKNIGDINQDGYPDIAVGAPY---DDLGKVFIYHGSAN 415

Query: 412  GLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVI 471
            G+N  P+Q+L+G      + P FGYS+ G  D+D+N YPD+ VG+   D   ++R+RPVI
Sbjct: 416  GINTKPTQVLKG------ISPYFGYSIAGNMDLDRNSYPDVAVGSLS-DSVTIFRSRPVI 468

Query: 472  TVNAGLEVYPSILNQDNKT-CSLPGTALKVSCFNVRFCLK--ADGKGVLPRKLNFQVELL 528
             +   + V P+ ++   KT C  P       C  V+ C +  A+  G  P  ++    L 
Sbjct: 469  NIQKTITVTPNRIDLRQKTACGAPSGI----CLQVKSCFEYTANPAGYNP-SISIVGTLE 523

Query: 529  LDKLKQK-GAIRRALFLYSRS-PSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPIT 586
             +K ++K G   R  F    S P +++ +T+ R     C E   +L+D    RDKL PI 
Sbjct: 524  AEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDN--IRDKLRPIP 581

Query: 587  IFMEYRLDY----RTAADTTGLQPILNQFTPANISRQAHILLD-CGEDNVCKPKLEVSV- 640
            I     +      R       + PILN   P       H L + CG+DNVC   L++   
Sbjct: 582  ITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYK 641

Query: 641  ----DSDQKK------------IYIGDDNPLTLIVKAQNQ----------GEGAYEAELI 674
                + +Q K            + + D   + L +   N           G+ A+EA+LI
Sbjct: 642  FCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLI 701

Query: 675  VSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQ 734
             + P    +    R   A      +        Q  C+LGNP K  + +   L  S  + 
Sbjct: 702  ATFPDTLTY-SAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEV 760

Query: 735  SEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKE 794
            +     +  +L++++++  D ++P+ + K  + +   + + GV+ P  ++        ++
Sbjct: 761  TFDTPDLDINLKLETTSNQDNLAPITA-KAKVVIELLLSVSGVAKPSQVYFG-GTVVGEQ 818

Query: 795  NPETEEDVGPVVQHIYELRNNGP--SSFSKAMLHLQWPYKYNNNT-LLYILHYDIDG--P 849
              ++E++VG ++++ + + N G   ++   A L++QWP + +N   LLY++  +  G   
Sbjct: 819  AMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEK 878

Query: 850  MNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGV-AQ 908
            + C    EIN L +  S     ++  T     E+     ++    +E    TL C V   
Sbjct: 879  VTCEPQKEINSLNLTESHNSRKKREIT-----EKQIDDNRKFSLFAERKYQTLNCSVNVN 933

Query: 909  CLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPI 968
            C+ I C +  LD   S IL  +S LW  TF+ + ++ +   +   A  +V     +N+ +
Sbjct: 934  CVNIRCPLRGLDSKASLIL--RSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAA-ENIRL 990

Query: 969  EDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKR 1023
             +      VT   +  +      VP W+I++A+LAG+L+LA+LVF++++ GFFKR
Sbjct: 991  PNAGTQVRVTVFPSKTVAQYS-GVPWWIILVAILAGILMLALLVFILWKCGFFKR 1044


>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
          Length = 1137

 Score =  319 bits (817), Expect = 1e-86
 Identities = 322/1116 (28%), Positives = 509/1116 (45%), Gaps = 141/1116 (12%)

Query: 6    RRRLRLGPRGLPLLLSGLLLPL----CRAFNLDVDSPAEYSGPEGSYFGFAVDFFVP-SA 60
            R R   G  G+  L   LL+ L      AFNLDV       G  GS FGF+V        
Sbjct: 5    RSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQP 64

Query: 61   SSRMFLLVGAPKANTTQPGIVEG--GQVLKCDWSSTRR-CQPIEFDATGNRDYAKDDPLE 117
              + +LLVGAP+A    PG      G +  C  S     C  ++ D         D   E
Sbjct: 65   RPQSWLLVGAPQA-LALPGQQANRTGGLFACPLSLEETDCYRVDIDQ------GADMQKE 117

Query: 118  FKSHQWFGASVRSKQD--KILACAPLYHWRTEMKQ---EREPVGTCF-------LQDGTK 165
             K +QW G SVRS+    KI+ CA  Y  R  + Q    R+ +G CF       ++D   
Sbjct: 118  SKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELD 177

Query: 166  TVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLL-GGPGSFYWQGQLISDQVAEIVSK 224
              E+  C  +    +  GFCQ G +  F+     LL G PG++ W+G L    +    S 
Sbjct: 178  GGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDS--SD 235

Query: 225  YDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGID-----DFVSGVPRAART 279
             D  VY            A  +  +SYLG+S+     +G G+       FV+G PRA   
Sbjct: 236  PDQLVYKTLDPADRLPGPAGDLALNSYLGFSID----SGKGLVRAEELSFVAGAPRANHK 291

Query: 280  LGMVYIYDGKNMSSLYN---FTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSD 336
             G V I    + S L      +GE++ + FG+S+A  D+N D + D+ +GAP F +R  +
Sbjct: 292  -GAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEE 350

Query: 337  GKLQEVGQVSVSLQRAS--GDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPY 394
                  G V V L +          +L G    + FG ++A LGDL+QDGF DIA+ AP+
Sbjct: 351  LG----GAVYVYLNQGGHWAGISPLRLCG-SPDSMFGISLAVLGDLNQDGFPDIAVGAPF 405

Query: 395  GGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIV 454
             G+ K   V+I++G S G+ A PSQ+LEG+        SFGYS+ G+ D+D N YPDL+V
Sbjct: 406  DGDGK---VFIYHGSSLGVVAKPSQVLEGEAVGIK---SFGYSLSGSLDMDGNQYPDLLV 459

Query: 455  GAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLK--AD 512
            G+   D A+L+RARP++ V+  + + P  ++ +   C+   +     C ++R C    A 
Sbjct: 460  GSL-ADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSV----CVDLRVCFSYIAV 514

Query: 513  GKGVLPR-KLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELI-- 569
                 P   L++ ++   D+ + +G + R  FL SR+    K+       L    + +  
Sbjct: 515  PSSYSPTVALDYVLDADTDR-RLRGQVPRVTFL-SRNLEEPKHQASGTVWLKHQHDRVCG 572

Query: 570  -AYLRDESEFRDKLTPITIFMEYRLD---YRTAADTTGL---QPILNQFTPANISRQAHI 622
             A  + +   +DKL  I + + Y L     R  A   GL    PILN   P+    + H 
Sbjct: 573  DAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHF 632

Query: 623  LLD-CGEDNVCKPKLEV--------SVDSDQKKIYIGDDNPLTLI--------------- 658
            L   CGED +C+  L++          D++ + + +  D    L                
Sbjct: 633  LKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVT 692

Query: 659  ------VKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCD 712
                   + Q  G+ A+EA+L+V +P    + GV   + A   L      EN +  V C+
Sbjct: 693  NLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPL--CLSNENAS-HVECE 749

Query: 713  LGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAV 772
            LGNPMK G Q+   L  S    S   T ++ +L +  + + ++    VS +  + +   +
Sbjct: 750  LGNPMKRGAQVTFYLILSTSGISIETTELEVELLL--ATISEQELHPVSARARVFIELPL 807

Query: 773  EIRGVSSPDHIFLP-IPNWEHKENPETEEDVGPVVQHIYELRNNGPS--SFSKAMLHLQW 829
             I G++ P  +F   +   E     ++E DVG  V++   + N G S  +   A L++ W
Sbjct: 808  SIAGMAIPQQLFFSGVVRGERA--MQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMW 865

Query: 830  PYKY-NNNTLLYILHYDIDG-----------PMNCTSDMEINPLRIKISSLQTTEKNDTV 877
            P++  N   LLY +  +++G           P      ++++    +   L+  E+ +  
Sbjct: 866  PHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQE-- 923

Query: 878  AGQGERDHLITKRDLALSEGDIHTLGC--GVAQCLKIVCQVGRLDRGKSAILYVKSLLWT 935
             G+ +   +      +  +    TL C  G A C+   C +   DR  +A+L+V   LW 
Sbjct: 924  PGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDR--AAVLHVWGRLWN 981

Query: 936  ETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPM---PV 992
             TF+ + +   S  +   A+  V +   KNL + D   ST++   V   + P  +    V
Sbjct: 982  STFLEEYSAVKSLEVIVRANITV-KSSIKNLMLRDA--STVIPVMVY--LDPMAVVAEGV 1036

Query: 993  PVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQ 1028
            P WVI+LAVLAGLL+LA+LV ++++MGFFKR + P+
Sbjct: 1037 PWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPE 1072


>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
          Length = 1141

 Score =  314 bits (804), Expect = 3e-85
 Identities = 319/1119 (28%), Positives = 510/1119 (45%), Gaps = 143/1119 (12%)

Query: 6    RRRLRLGPRGLPLLLSGLLLPL----CRAFNLDVDSPAEYSGPEGSYFGFAVDFFVP-SA 60
            R R   G  G+  L   LL+ L      AFNLDV       G  GS FGF+V        
Sbjct: 5    RSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQP 64

Query: 61   SSRMFLLVGAPKANTTQPGIVEG--GQVLKCDWSSTRR-CQPIEFDATGNRDYAKDDPLE 117
              + +LLVGAP+A    PG      G +  C  S     C  ++ D         D   E
Sbjct: 65   RPQSWLLVGAPQA-LALPGQQANRTGGLFACPLSLEETDCYRVDIDQ------GADMQKE 117

Query: 118  FKSHQWFGASVRSKQD--KILACAPLYHWRTEMKQ---EREPVGTCF-------LQDGTK 165
             K +QW G SVRS+    KI+ CA  Y  R  + Q    R+ +G CF       ++D   
Sbjct: 118  SKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELD 177

Query: 166  TVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLL-GGPGSFYWQGQL---ISDQVAEI 221
              E+  C  +    +  GFCQ G +  F+     LL G PG++ W+G     +  Q +  
Sbjct: 178  GGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSAD 237

Query: 222  VSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGID-----DFVSGVPRA 276
            ++  D   Y      +   R    +  +SY G+S+     +G G+       FV+G PRA
Sbjct: 238  LAHLDDGPYEAGGEKEQDPRLIP-VPANSYFGFSID----SGKGLVRAEELSFVAGAPRA 292

Query: 277  ARTLGMVYIYDGKNMSSLYN---FTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDR 333
                G V I    + S L      +GE++ + FG+S+A  D+N D + D+ +GAP F +R
Sbjct: 293  NHK-GAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFER 351

Query: 334  GSDGKLQEVGQVSVSLQRAS--GDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIA 391
              +      G V V L +          +L G    + FG ++A LGDL+QDGF DIA+ 
Sbjct: 352  QEELG----GAVYVYLNQGGHWAGISPLRLCG-SPDSMFGISLAVLGDLNQDGFPDIAVG 406

Query: 392  APYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPD 451
            AP+ G+ K   V+I++G S G+ A PSQ+LEG+        SFGYS+ G+ D+D N YPD
Sbjct: 407  APFDGDGK---VFIYHGSSLGVVAKPSQVLEGEAVGIK---SFGYSLSGSLDMDGNQYPD 460

Query: 452  LIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLK- 510
            L+VG+   D A+L+RARP++ V+  + + P  ++ +   C+   +     C ++R C   
Sbjct: 461  LLVGSL-ADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSV----CVDLRVCFSY 515

Query: 511  -ADGKGVLPR-KLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEEL 568
             A      P   L++ ++   D+ + +G + R  FL SR+    K+       L    + 
Sbjct: 516  IAVPSSYSPTVALDYVLDADTDR-RLRGQVPRVTFL-SRNLEEPKHQASGTVWLKHQHDR 573

Query: 569  I---AYLRDESEFRDKLTPITIFMEYRLD---YRTAADTTGL---QPILNQFTPANISRQ 619
            +   A  + +   +DKL  I + + Y L     R  A   GL    PILN   P+    +
Sbjct: 574  VCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAE 633

Query: 620  AHILLD-CGEDNVCKPKLEV--------SVDSDQKKIYIGDDNPLTLI------------ 658
             H L   CGED +C+  L++          D++ + + +  D    L             
Sbjct: 634  IHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLEL 693

Query: 659  ---------VKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQV 709
                      + Q  G+ A+EA+L+V +P    + GV   + A   L      EN +  V
Sbjct: 694  MVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPL--CLSNENAS-HV 750

Query: 710  VCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVL 769
             C+LGNPMK G Q+   L  S    S   T ++ +L +  + + ++    VS +  + + 
Sbjct: 751  ECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLL--ATISEQELHPVSARARVFIE 808

Query: 770  AAVEIRGVSSPDHIFLP-IPNWEHKENPETEEDVGPVVQHIYELRNNGPS--SFSKAMLH 826
              + I G++ P  +F   +   E     ++E DVG  V++   + N G S  +   A L+
Sbjct: 809  LPLSIAGMAIPQQLFFSGVVRGERA--MQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLN 866

Query: 827  LQWPYKY-NNNTLLYILHYDIDG-----------PMNCTSDMEINPLRIKISSLQTTEKN 874
            + WP++  N   LLY +  +++G           P      ++++    +   L+  E+ 
Sbjct: 867  IMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQ 926

Query: 875  DTVAGQGERDHLITKRDLALSEGDIHTLGC--GVAQCLKIVCQVGRLDRGKSAILYVKSL 932
            +   G+ +   +      +  +    TL C  G A C+   C +   DR  +A+L+V   
Sbjct: 927  E--PGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDR--AAVLHVWGR 982

Query: 933  LWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPM-- 990
            LW  TF+ + +   S  +   A+  V +   KNL + D   ST++   V   + P  +  
Sbjct: 983  LWNSTFLEEYSAVKSLEVIVRANITV-KSSIKNLMLRDA--STVIPVMVY--LDPMAVVA 1037

Query: 991  -PVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQ 1028
              VP WVI+LAVLAGLL+LA+LV ++++MGFFKR + P+
Sbjct: 1038 EGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPE 1076


>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
          Length = 1032

 Score =  296 bits (757), Expect = 9e-80
 Identities = 294/1096 (26%), Positives = 485/1096 (44%), Gaps = 113/1096 (10%)

Query: 1    MAFPPRRR---LRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFV 57
            MA+  RR     R   R   +LL  L +P  R +N+D +S   Y GP  + FG++V   +
Sbjct: 1    MAWEARREPGPRRAAVRETVMLLLCLGVPTGRPYNVDTESALLYQGPHNTLFGYSV--VL 58

Query: 58   PSASSRMFLLVGAPKAN-TTQPGIVEGGQVLKCDWSST--RRCQPIEFDATGNRDYAKDD 114
             S  +  +LLVGAP AN      ++  G + +C       + C+ ++  +       K  
Sbjct: 59   HSHGANRWLLVGAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTC 118

Query: 115  PLEFKSHQWFGASVR---SKQDKILACAPLYHWRT--EMKQERE-PVGTCFLQDGTKTVE 168
             LE + +QW G ++     +   I+ C   + W+    +K E + P G C+        E
Sbjct: 119  -LEERDNQWLGVTLSRQPGENGSIVTCG--HRWKNIFYIKNENKLPTGGCYGVPPDLRTE 175

Query: 169  Y----APCRSQDIDADGQGF--CQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIV 222
                 APC    +   G+ F  CQ G S  +TK D +++G PGS YW G L         
Sbjct: 176  LSKRIAPCYQDYVKKFGENFASCQAGISSFYTK-DLIVMGAPGSSYWTGSLF-------- 226

Query: 223  SKYDPNVYSIKYNNQLATRTAQ-AIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLG 281
                  VY+I  N   A    Q  +   SYLGYSV  G F      + V G P+  + +G
Sbjct: 227  ------VYNITTNKYKAFLDKQNQVKFGSYLGYSVGAGHFRSQHTTEVVGGAPQHEQ-IG 279

Query: 282  MVYIY--DGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKL 339
              YI+  D K ++ L+   G+++ +YFG SV A D+N D ++D+ +GAP+         +
Sbjct: 280  KAYIFSIDEKELNILHEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPM------QSTI 333

Query: 340  QEVGQVSVSLQRASG---DFQTTKLNGFEVFA-RFGSAIAPLGDLDQDGFNDIAIAAPYG 395
            +E G+V V +   SG   +   T L G + +A RFG +I  LGD+D DGF D+AI AP  
Sbjct: 334  REEGRVFVYINSGSGAVMNAMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQE 393

Query: 396  GEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVG 455
             +D +G +YI+NGR+ G+++  SQ +EG   ++S+   FG S+ G  D D NGY D+ VG
Sbjct: 394  -DDLQGAIYIYNGRADGISSTFSQRIEGLQISKSLS-MFGQSISGQIDADNNGYVDVAVG 451

Query: 456  AFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKG 515
            AF  D A+L R RPV+ V+A L  +P  +N+    C   G      C ++  C    GK 
Sbjct: 452  AFRSDSAVLLRTRPVVIVDASLS-HPESVNRTKFDCVENG--WPSVCIDLTLCFSYKGKE 508

Query: 516  VLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDE 575
            V P  +     + LD  ++  +  R  F  + +                C    A++R  
Sbjct: 509  V-PGYIVLFYNMSLDVNRKAESPPRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMR-- 565

Query: 576  SEFRDKLTPITIFMEYRL-----DYRTAADTTGLQPILNQFTPANISRQA-HILLDCGED 629
             + RD LTPI I   Y L       R+  +   LQPIL Q    +I ++  +    C  +
Sbjct: 566  KDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHE 625

Query: 630  NVCKPKLEVS-----VDSDQKKIY--IGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQAD 682
            N C   L+VS     +   + K Y  +G    L L V   N G+ AYE  L V +P+   
Sbjct: 626  N-CSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLY 684

Query: 683  FIGVVRNNEALARLSCAFKTENQTRQVVCDLGN---PMKAGTQLLAGLRFSVHQQSEMDT 739
            FI ++   E   +++C     +   Q+ C +G       +   +   L  S   ++E D 
Sbjct: 685  FIKILELEE--KQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDL 742

Query: 740  SVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETE 799
            S+      ++    D +      +V +A+    E++      H F+   ++ +  N E E
Sbjct: 743  SITVHATCENEEEMDNLK---HSRVTVAIPLKYEVK---LTVHGFVNPTSFVYGSNDENE 796

Query: 800  EDVGPV--VQHIYELRNNGPSSFSKAMLHLQWPYKYNNNT--LLYILHYD-IDGPMNCTS 854
             +   V  +   + + N G S      + +  P  ++  T  L  IL      G  +  +
Sbjct: 797  PETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLFNILDVQTTTGECHFEN 856

Query: 855  DMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVC 914
               +  L  + S++QT +    V    + D    KR L   + D H        CL  +C
Sbjct: 857  YQRVCALEQQKSAMQTLK--GIVRFLSKTD----KRLLYCIKADPH--------CLNFLC 902

Query: 915  QVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNS 974
              G+++ GK A ++++           E     + ++++       FP  N  + ++   
Sbjct: 903  NFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATG------FPEPNPRVIELNKD 956

Query: 975  TLVTTNVTWGI--QPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKR-VRPPQEEQ 1031
              V   +  G+  Q       + +I  ++L GL++L ++ +VM++ GFFKR  +   +E+
Sbjct: 957  ENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEE 1016

Query: 1032 EREQLQPHENGEGNSE 1047
             R     + N + N +
Sbjct: 1017 NRRDSWSYINSKSNDD 1032


>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
          Length = 1044

 Score =  276 bits (707), Expect = 6e-74
 Identities = 272/977 (27%), Positives = 451/977 (46%), Gaps = 126/977 (12%)

Query: 138  CAPLYHWRTEMKQ---EREPVGTCF-------LQDGTKTVEYAPCRSQDIDADGQGFCQG 187
            CA  Y  R  + Q    R+ +G CF       ++D     E+  C  +    +  GFCQ 
Sbjct: 43   CAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQ 102

Query: 188  GFSIDFTKADRVLL-GGPGSFYWQGQL---ISDQVAEIVSKYDPNVYSIKYNNQLATRTA 243
            G +  F+     LL G PG++ W+G     +  Q +  ++  D   Y      +   R  
Sbjct: 103  GTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLI 162

Query: 244  QAIFDDSYLGYSVAVGDFNGDGID-----DFVSGVPRAARTLGMVYIYDGKNMSSLYN-- 296
              +  +SY G+S+     +G G+       FV+G PRA    G V I    + S L    
Sbjct: 163  P-VPANSYFGFSID----SGKGLVRAEELSFVAGAPRANHK-GAVVILRKDSASRLVPEV 216

Query: 297  -FTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRAS-- 353
              +GE++ + FG+S+A  D+N D + D+ +GAP F +R  +      G V V L +    
Sbjct: 217  MLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELG----GAVYVYLNQGGHW 272

Query: 354  GDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGL 413
                  +L G    + FG ++A LGDL+QDGF DIA+ AP+ G+ K   V+I++G S G+
Sbjct: 273  AGISPLRLCG-SPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGK---VFIYHGSSLGV 328

Query: 414  NAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITV 473
             A PSQ+LEG+        SFGYS+ G+ D+D N YPDL+VG+   D A+L+RARP++ V
Sbjct: 329  VAKPSQVLEGEAVGIK---SFGYSLSGSLDMDGNQYPDLLVGSL-ADTAVLFRARPILHV 384

Query: 474  NAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLK--ADGKGVLPR-KLNFQVELLLD 530
            +  + + P  ++ +   C+   +     C ++R C    A      P   L++ ++   D
Sbjct: 385  SHEVSIAPRSIDLEQPNCAGGHSV----CVDLRVCFSYIAVPSSYSPTVALDYVLDADTD 440

Query: 531  KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELI---AYLRDESEFRDKLTPITI 587
            + + +G + R  FL SR+    K+       L    + +   A  + +   +DKL  I +
Sbjct: 441  R-RLRGQVPRVTFL-SRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVV 498

Query: 588  FMEYRLD---YRTAADTTGL---QPILNQFTPANISRQAHILLD-CGEDNVCKPKLEV-- 638
             + Y L     R  A   GL    PILN   P+    + H L   CGED +C+  L++  
Sbjct: 499  TLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVR 558

Query: 639  ------SVDSDQKKIYIGDDNPLTLI---------------------VKAQNQGEGAYEA 671
                    D++ + + +  D    L                       + Q  G+ A+EA
Sbjct: 559  ARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEA 618

Query: 672  ELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSV 731
            +L+V +P    + GV   + A   L      EN +  V C+LGNPMK G Q+   L  S 
Sbjct: 619  QLLVMLPDSLHYSGVRALDPAEKPL--CLSNENAS-HVECELGNPMKRGAQVTFYLILST 675

Query: 732  HQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLP-IPNW 790
               S   T ++ +L +  + + ++    VS +  + +   + I G++ P  +F   +   
Sbjct: 676  SGISIETTELEVELLL--ATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRG 733

Query: 791  EHKENPETEEDVGPVVQHIYELRNNGPS--SFSKAMLHLQWPYKY-NNNTLLYILHYDID 847
            E     ++E DVG  V++   + N G S  +   A L++ WP++  N   LLY +  +++
Sbjct: 734  ERA--MQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELE 791

Query: 848  G-----------PMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSE 896
            G           P      ++++    +   L+  E+ +   G+ +   +      +  +
Sbjct: 792  GGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQE--PGERQEPSMSWWPVSSAEK 849

Query: 897  GDIHTLGC--GVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSA 954
                TL C  G A C+   C +   DR  +A+L+V   LW  TF+ + +   S  +   A
Sbjct: 850  KKNITLDCARGTANCVVFSCPLYSFDR--AAVLHVWGRLWNSTFLEEYSAVKSLEVIVRA 907

Query: 955  SFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPM---PVPVWVIILAVLAGLLLLAVL 1011
            +  V +   KNL + D   ST++   V   + P  +    VP WVI+LAVLAGLL+LA+L
Sbjct: 908  NITV-KSSIKNLMLRDA--STVIPVMVY--LDPMAVVAEGVPWWVILLAVLAGLLVLALL 962

Query: 1012 VFVMYRMGFFKRVRPPQ 1028
            V ++++MGFFKR + P+
Sbjct: 963  VLLLWKMGFFKRAKHPE 979


>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
          Length = 1035

 Score =  270 bits (690), Expect = 5e-72
 Identities = 283/1101 (25%), Positives = 490/1101 (44%), Gaps = 137/1101 (12%)

Query: 5    PRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRM 64
            PR   RL    L L+++G+      A+NLD   P  + GP  S+FG+AV        +  
Sbjct: 7    PRGAGRLRALLLALVVAGIP---AGAYNLDPQRPVHFQGPADSFFGYAV--LEHFHDNTR 61

Query: 65   FLLVGAPKANTT-QPGIVEGGQVLKC--DWSSTRRCQPIEFDATGNRDYAKDDPL-EFKS 120
            ++LVGAPKA++   P +   G V KC    +  RRC  ++     NR  +      E + 
Sbjct: 62   WVLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRD 121

Query: 121  HQWFGASV--RSKQD-KILACAPLYHWRTEMKQERE--PVGTCFLQDGT---KTVEYAPC 172
             +W G S+  + K D ++LACA  + W+    +     P G C++       K     PC
Sbjct: 122  DEWMGVSLARQPKADGRVLACA--HRWKNIYYEADHILPHGFCYIIPSNLQAKGRTLIPC 179

Query: 173  RSQDIDADGQ--GFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVY 230
              +     G+  G CQ G +  FT+ + V++G PGSFYW G +      ++++  D N Y
Sbjct: 180  YEEYKKKYGEEHGSCQAGIAGFFTE-ELVVMGAPGSFYWAGTI------KVLNLTD-NTY 231

Query: 231  SIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKN 290
             +K N+++           +YLGY+V  G F+     D V G P+  + +G VYI+    
Sbjct: 232  -LKLNDEVIMNRRY-----TYLGYAVTAGHFSHPSTIDVVGGAPQD-KGIGKVYIFRADR 284

Query: 291  MSS----LYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVS 346
             S     ++  +G++M +YFG S+ A D+NGD  +D+ +GAP+F +      +++ GQV+
Sbjct: 285  RSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSE------IRDEGQVT 338

Query: 347  VSLQRASGDFQTT-KLNGFEVF-ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVY 404
            V + R +G  +    L G   + A FG +IA L DLD DGF D+AI AP   +D  G VY
Sbjct: 339  VYINRGNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKE-DDFAGAVY 397

Query: 405  IFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAIL 464
            I++G + G+    S  L GQ     +   FG S+ G  D+D NGYPD+ VGAF  D  +L
Sbjct: 398  IYHGDAGGIVPQYSMKLSGQ-KINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVL 456

Query: 465  YRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQ 524
             RARPVITV+  +   P  +N     C        V+C NV  C    GK V P ++   
Sbjct: 457  LRARPVITVDVSI-FLPGSINITAPQCH--DGQQPVNCLNVTTCFSFHGKHV-PGEIGLN 512

Query: 525  VELLLD-KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQ-CEELIAYLRDESEFRDKL 582
              L+ D   K+KG + R  F+            +    + + C   +A+++     +D +
Sbjct: 513  YVLMADVAKKEKGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVK--RRVQDVI 570

Query: 583  TPITIFMEYRLDYRTAA----DTTGLQPILNQFTPANISRQAHILL-------DCGEDNV 631
            +PI     Y L          +   L P+L       I+++   +        DC  D  
Sbjct: 571  SPIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSEDCAADLQ 630

Query: 632  CKPKLEVSVDSDQKKIY--IGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRN 689
             + KL +S   D+K +Y  +G    ++L +   N G+ AY+A +  ++  +  FI + + 
Sbjct: 631  LQGKLLLS-SMDEKTLYLALGAVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQK 689

Query: 690  NEALARLSCAFKTENQTRQVVCDLGNP-MKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQ 748
             E    +SC     +  +   C +G P M++ ++    + F     S  +  + F +  Q
Sbjct: 690  EE--MGISCELLESDFLK---CSVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQ 744

Query: 749  SSN------LFDKVSPV---VSHKVDLAVLAAVE----IRGVSSPDHIFLPIPNWEHKEN 795
            S N      L D    +   + H+VD ++   +     + G S     F+ + + E    
Sbjct: 745  SGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQ 804

Query: 796  PETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNN-NTLLYILHYDIDGPMNCTS 854
            P         +    ++ N GPS+   + + + +P + ++    ++ +   + G      
Sbjct: 805  P---------INITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNC 855

Query: 855  DMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGC---GVAQCLK 911
              + NP    I                E++++        ++     L C   G++ CL 
Sbjct: 856  SFQKNPTPCIIPQ--------------EQENIFHTIFAFFTKSGRKVLDCEKPGIS-CLT 900

Query: 912  IVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSY----SLKSSASFNVIEFPYKNLP 967
              C    L + +S  + +  LL TE      +    +     +K   +  V+E  + N  
Sbjct: 901  AHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGN-- 958

Query: 968  IEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPP 1027
             E++T    V       ++P    V  W+I +++L G+L+  +L  ++++MGFF+R    
Sbjct: 959  PEEVT----VVFEALHNLEPRGYVVG-WIIAISLLVGILIFLLLAVLLWKMGFFRR---- 1009

Query: 1028 QEEQEREQLQPHENGEGNSET 1048
               + +E ++  +N + N ++
Sbjct: 1010 ---RYKEIIEAEKNRKENEDS 1027


>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
          Length = 1051

 Score =  270 bits (690), Expect = 5e-72
 Identities = 301/1094 (27%), Positives = 474/1094 (43%), Gaps = 160/1094 (14%)

Query: 13   PRGLPLLLSGLLLPLCR------AFNLDVDS-PAEYSGPEGSYFGFAVDFFVPSA-SSRM 64
            PR   L+L  L L +        AFNLD      + +G  GS FG++V     +    R 
Sbjct: 9    PRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRY 68

Query: 65   FLLVGAPKANTTQPGIVEG-GQVLKCDWSSTRRCQPIEFDATGNRDYAKDDP-LEFKSHQ 122
             LL GAP+      G     G V  C  ++ +       D        K+DP        
Sbjct: 69   LLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKD------DCERMNITVKNDPGHHIIEDM 122

Query: 123  WFGASVRSK--QDKILACAPLYH---WRTEMKQEREPVGTCFLQ---------DGTKTVE 168
            W G +V S+    ++L CA  Y    W +  + +R  VG C+++         D  +T  
Sbjct: 123  WLGVTVASQGPAGRVLVCAHRYTQVLW-SGSEDQRRMVGKCYVRGNDLELDSSDDWQTYH 181

Query: 169  YAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPN 228
               C S + D    G CQ G S  FT+ + V  G PG++ W+G     Q  E    +D +
Sbjct: 182  NEMCNS-NTDYLETGMCQLGTSGGFTQ-NTVYFGAPGAYNWKGNSYMIQRKE----WDLS 235

Query: 229  VYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDF--NGDGIDDFVSGVPRAARTLGMVYIY 286
             YS K               + Y+GY++ VG F  +   I   V+G PR  R +G V++ 
Sbjct: 236  EYSYKDPEDQG---------NLYIGYTMQVGSFILHPKNIT-IVTGAPRH-RHMGAVFLL 284

Query: 287  D---GKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVG 343
                G ++       G Q+ AYFG ++A  D+N D + D+ +GAP + +R    K +  G
Sbjct: 285  SQEAGGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFER----KEEVGG 340

Query: 344  QVSVSLQRASGDFQ---TTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKK 400
             + V + +A   F    +  L+G    A FG ++A +GD++QDGF DIA+ AP+ G  K 
Sbjct: 341  AIYVFMNQAGTSFPAHPSLLLHGPSGSA-FGLSVASIGDINQDGFQDIAVGAPFEGLGK- 398

Query: 401  GIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVD 460
              VYI++  S GL   P Q++ G+        +FGYS+ G  D+D+N YPDL+VG+   D
Sbjct: 399  --VYIYHSSSKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLS-D 455

Query: 461  RAILYRARPVIT-VNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCL---KADGKGV 516
              +L RARPVI  V+  L   P++L+        P      SC  V  C    ++ G   
Sbjct: 456  HIVLLRARPVINIVHKTLVPRPAVLD--------PALCTATSCVQVELCFAYNQSAGNPN 507

Query: 517  LPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDES 576
              R +     L  D+ ++   +R   F  S S       ++     M+C++L   L D  
Sbjct: 508  YRRNITLAYTLEADRDRRPPRLR---FAGSESAVFHGFFSMPE---MRCQKLELLLMD-- 559

Query: 577  EFRDKLTPITIFMEYRLDYRTA-ADTTGLQ-----PILNQFTPANISRQAHILLDCGEDN 630
              RDKL PI I M Y L  R       GL+     PILNQ        +     +CG DN
Sbjct: 560  NLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPDN 619

Query: 631  VCKPKLEVS---VDSDQKKI----YIGDDNPLTLIVKAQN------QGEGAYEAELIVSI 677
             C+  L++    V   Q+K+    Y  D   L L +   N       GE A+EA L + +
Sbjct: 620  KCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVV 679

Query: 678  PLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEM 737
            P  A  +  VR   A           N+T  + C+LGNP K   ++   + F V   +  
Sbjct: 680  P-PALLLSSVRPPGAC--------QANET--IFCELGNPFKRNQRMELLIAFEVIGVTLH 728

Query: 738  DTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIR-GVSSPDHIFLPI--PNWEHKE 794
               ++  LQ+ +S+  D + P++     L +L    ++  +S  +H            + 
Sbjct: 729  TRDLQVQLQLSTSSHQDNLWPMI-----LTLLVDYTLQTSLSMVNHRLQSFFGGTVMGES 783

Query: 795  NPETEEDVGPVVQHIYEL--RNNGPSSFSKAMLHLQWPYKYNNNT-LLYILHYDIDG--- 848
              +T EDVG  +++ +++     G       +L L+WPY+ +N   LLY     + G   
Sbjct: 784  GMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGS 843

Query: 849  -PMNCTSDMEINPLRIKISS--------LQTTEKNDTVAGQGERDHLITKRDLALSEGDI 899
             P     D+ INPL + +S          +   + D   GQG     +     A SE  +
Sbjct: 844  WPCRPPGDL-INPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSE-TV 901

Query: 900  HTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVI 959
             T   G A C+ + C +   D      + VK+ +W  TF+          +   A+    
Sbjct: 902  LTCATGRAHCVWLECPIP--DAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATL--- 956

Query: 960  EFPYKNLPIEDITNSTLVTTNVTWG--------IQPAPMPVPVWVIILAVLAGLLLLAVL 1011
             F   ++P  ++ N T      TW         ++  P  + +W++++AV AGLLLL ++
Sbjct: 957  -FLRTSIPTINMENKT------TWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLI 1009

Query: 1012 VFVMYRMGFFKRVR 1025
            + ++++ GFFKR R
Sbjct: 1010 ILLLWKCGFFKRAR 1023


>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
          Length = 1066

 Score =  267 bits (683), Expect = 3e-71
 Identities = 300/1094 (27%), Positives = 473/1094 (43%), Gaps = 160/1094 (14%)

Query: 13   PRGLPLLLSGLLLPLCR------AFNLDVDS-PAEYSGPEGSYFGFAVDFFVPSA-SSRM 64
            PR   L+L  L L +        AFNLD      + +G  GS FG++V     +    R 
Sbjct: 9    PRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRY 68

Query: 65   FLLVGAPKANTTQPGIVEG-GQVLKCDWSSTRRCQPIEFDATGNRDYAKDDP-LEFKSHQ 122
             LL GAP+      G     G V  C  ++ +       D        K+DP        
Sbjct: 69   LLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKD------DCERMNITVKNDPGHHIIEDM 122

Query: 123  WFGASVRSK--QDKILACAPLYH---WRTEMKQEREPVGTCFLQ---------DGTKTVE 168
            W G +V S+    ++L CA  Y    W +  + +R  VG C+++         D  +T  
Sbjct: 123  WLGVTVASQGPAGRVLVCAHRYTQVLW-SGSEDQRRMVGKCYVRGNDLELDSSDDWQTYH 181

Query: 169  YAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPN 228
               C S + D    G CQ G S  FT+ + V  G PG++ W+G     Q  E    +D +
Sbjct: 182  NEMCNS-NTDYLETGMCQLGTSGGFTQ-NTVYFGAPGAYNWKGNSYMIQRKE----WDLS 235

Query: 229  VYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDF--NGDGIDDFVSGVPRAARTLGMVYIY 286
             YS K               + Y+GY++ VG F  +   I   V+G PR  R +G V++ 
Sbjct: 236  EYSYKDPEDQG---------NLYIGYTMQVGSFILHPKNIT-IVTGAPRH-RHMGAVFLL 284

Query: 287  D---GKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVG 343
                G ++       G Q+ AYFG ++A  D+N D + D+ +GAP + +R    K +  G
Sbjct: 285  SQEAGGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFER----KEEVGG 340

Query: 344  QVSVSLQRASGDFQ---TTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKK 400
             + V + +A   F    +  L+G    A FG ++A +GD++QDGF DIA+ AP+ G  K 
Sbjct: 341  AIYVFMNQAGTSFPAHPSLLLHGPSGSA-FGLSVASIGDINQDGFQDIAVGAPFEGLGK- 398

Query: 401  GIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVD 460
              VYI++  S GL   P Q++ G+        +FGYS+ G  D+D+N YPDL+VG+   D
Sbjct: 399  --VYIYHSSSKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLS-D 455

Query: 461  RAILYRARPVIT-VNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCL---KADGKGV 516
              +L RARPVI  V+  L   P++L+        P      SC  V  C    ++ G   
Sbjct: 456  HIVLLRARPVINIVHKTLVPRPAVLD--------PALCTATSCVQVELCFAYNQSAGNPN 507

Query: 517  LPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDES 576
              R +     L  D+ ++   +R   F  S S       ++     M+C++L   L D  
Sbjct: 508  YRRNITLAYTLEADRDRRPPRLR---FAGSESAVFHGFFSMPE---MRCQKLELLLMD-- 559

Query: 577  EFRDKLTPITIFMEYRLDYRTA-ADTTGLQ-----PILNQFTPANISRQAHILLDCGEDN 630
              RDKL PI I M Y L  R       GL+     PILNQ        +     +CG DN
Sbjct: 560  NLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPDN 619

Query: 631  VCKPKLEVS---VDSDQKKI----YIGDDNPLTLIVKAQN------QGEGAYEAELIVSI 677
             C+  L++    V   Q+K+    Y  D   L L +   N       GE A+EA L + +
Sbjct: 620  KCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVV 679

Query: 678  PLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEM 737
            P  A  +  VR   A           N+T  + C+LGNP K   ++   + F V   +  
Sbjct: 680  P-PALLLSSVRPPGAC--------QANET--IFCELGNPFKRNQRMELLIAFEVIGVTLH 728

Query: 738  DTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIR-GVSSPDHIFLPI--PNWEHKE 794
               ++  LQ+ +S+  D + P++     L +L    ++  +S  +H            + 
Sbjct: 729  TRDLQVQLQLSTSSHQDNLWPMI-----LTLLVDYTLQTSLSMVNHRLQSFFGGTVMGES 783

Query: 795  NPETEEDVGPVVQHIYEL--RNNGPSSFSKAMLHLQWPYKYNNNT-LLYILHYDIDG--- 848
              +T EDVG  +++ +++     G       +L L+WPY+ +N   LLY     + G   
Sbjct: 784  GMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGS 843

Query: 849  -PMNCTSDMEINPLRIKISS--------LQTTEKNDTVAGQGERDHLITKRDLALSEGDI 899
             P     D+ INPL + +S          +   + D   GQG     +     A SE  +
Sbjct: 844  WPCRPPGDL-INPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSE-TV 901

Query: 900  HTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVI 959
             T   G A C+ + C +   D      + VK+ +W  TF+          +   A+    
Sbjct: 902  LTCATGRAHCVWLECPIP--DAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATL--- 956

Query: 960  EFPYKNLPIEDITNSTLVTTNVTWG--------IQPAPMPVPVWVIILAVLAGLLLLAVL 1011
             F   ++P  ++ N T      TW         ++  P  + +W++++AV AGLLLL ++
Sbjct: 957  -FLRTSIPTINMENKT------TWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLI 1009

Query: 1012 VFVMYRMGFFKRVR 1025
            + ++++  FFKR R
Sbjct: 1010 ILLLWKCDFFKRTR 1023


>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
          Length = 1179

 Score =  211 bits (537), Expect = 3e-54
 Identities = 223/886 (25%), Positives = 381/886 (43%), Gaps = 123/886 (13%)

Query: 186  QGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDP--NVYSIKYNNQLATRTA 243
            Q GFS  +++ D V+LG  G++ W G ++  + ++I+   +   NV S K N  LA    
Sbjct: 379  QTGFSAHYSQ-DWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLA---- 433

Query: 244  QAIFDDSYLGYSV-AVGDFNGDGIDDFVSGVPRAARTLGMVYIY---DGKNMSSLYNFTG 299
                  SYLGY+V +    +GD +  +++G PR   T G V IY   DG N+  L   +G
Sbjct: 434  ------SYLGYTVNSATASSGDVL--YIAGQPRYNHT-GQVIIYRMEDG-NIKILQTLSG 483

Query: 300  EQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSV-SLQRASGDFQ 357
            EQ+ +YFG  +  TDI+ D   D+  +GAP++M      + +E G+V V +L +   ++Q
Sbjct: 484  EQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGT----EKEEQGKVYVYALNQTRFEYQ 539

Query: 358  -------------------TTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGED 398
                               TT+       ARFG+AIA + DL+ DGFNDI I AP   +D
Sbjct: 540  MSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLE-DD 598

Query: 399  KKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFG 458
              G VYI++G    +    +Q +      +++   FG S+ G  D++ +G  D+ +G  G
Sbjct: 599  HGGAVYIYHGSGKTIRKEYAQRIPSGGDGKTLK-FFGQSIHGEMDLNGDGLTDVTIGGLG 657

Query: 459  VDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFC--LKADGKGV 516
               A L+ +R V  V   +   P+ +N   K C + G   +  C N   C  +K   K  
Sbjct: 658  --GAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGK--ETVCINATVCFDVKLKSKED 713

Query: 517  LPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDES 576
               + + Q  + LD L+Q   I R+ F  ++     +N+T+ +    +C +   Y+ D+ 
Sbjct: 714  TIYEADLQYRVTLDSLRQ---ISRSFFSGTQERKVQRNITVRKS---ECTKHSFYMLDKH 767

Query: 577  EFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKL 636
            +F+D +          LD+       G  P+L+   P ++        DCG    C   L
Sbjct: 768  DFQDSV-------RITLDFNLTDPENG--PVLDDSLPNSVHEYIPFAKDCGNKEKCISDL 818

Query: 637  EVSVDSDQKKIYI--GDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALA 694
             + V + +K + I    ++   + +  +N  + AY    IV       F G+    EA+ 
Sbjct: 819  SLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGI----EAIQ 874

Query: 695  RLSCAFKTENQTRQVVCDLGNP-MKAGTQLLAGLRFSVHQQSEMDT-----SVKFDLQIQ 748
            + SC          + C +G P ++ G  +   + F  +    M+      S   D +  
Sbjct: 875  KDSC-----ESNHNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEP 929

Query: 749  SSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQH 808
               L D V   V+  + +     ++    +S  HI +   N    E   + ED+G  +  
Sbjct: 930  PETLSDNV---VNISIPVKYEVGLQFYSSASEYHISIAA-NETVPEVINSTEDIGNEINI 985

Query: 809  IYELRNNGPSSFSKAMLHLQWPYKYNNN-TLLYILHYDIDGPMNCTSDMEINPLRIKISS 867
             Y +R +G     +  L + +P   +N   +LY          NC   +  +P  I    
Sbjct: 986  FYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGK 1045

Query: 868  LQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAIL 927
              TT            DHL          G I  L C   +   I C +   D  +   +
Sbjct: 1046 KMTTST----------DHL--------KRGTI--LDCNTCKFATITCNLTSSDISQ---V 1082

Query: 928  YVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQP 987
             V  +LW  TF+     + + +++        E   +N  +   +++      +      
Sbjct: 1083 NVSLILWKPTFIKSYFSSLNLTIRG-------ELRSENASLVLSSSNQKRELAIQISKDG 1135

Query: 988  APMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQER 1033
             P  VP+WVI+L+  AGLLLL +L+  ++++GFFK  RP +++ E+
Sbjct: 1136 LPGRVPLWVILLSAFAGLLLLMLLILALWKIGFFK--RPLKKKMEK 1179



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 42/145 (28%), Positives = 60/145 (41%), Gaps = 14/145 (9%)

Query: 5   PRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRM 64
           PR R R G       L  ++L  C +FN+DV +   +SGP    FG+ V  +       +
Sbjct: 3   PRPRARPGVAVACCWLLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWV 62

Query: 65  FL---LVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSH 121
            +   LVG PK  T        G V KC          ++ D   N      +  E K +
Sbjct: 63  LIGSPLVGQPKNRT--------GDVYKCPVGRGESLPCVKLDLPVNTSI--PNVTEVKEN 112

Query: 122 QWFGAS-VRSKQDKILACAPLYHWR 145
             FG++ V +     LAC PLY +R
Sbjct: 113 MTFGSTLVTNPNGGFLACGPLYAYR 137


>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
          Length = 1181

 Score =  199 bits (507), Expect = 9e-51
 Identities = 232/884 (26%), Positives = 385/884 (43%), Gaps = 117/884 (13%)

Query: 186  QGGFSIDFTKADRVL-LGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQ 244
            Q GFS D++  + +L LG  G+F W G ++             +   + +  Q   +  Q
Sbjct: 380  QVGFSADYSSQNDILMLGAVGAFGWSGTIVQKT----------SHGHLIFPKQAFDQILQ 429

Query: 245  AIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIY---DGKNMSSLYNFTGEQ 301
                 SYLGYSVA    +      FV+G PRA  T G + +Y   +  N++ +    G+Q
Sbjct: 430  DRNHSSYLGYSVAA--ISTGESTHFVAGAPRANYT-GQIVLYSVNENGNITVIQAHRGDQ 486

Query: 302  MAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK 360
            + +YFG  + + D++ D   DV  +GAP++M   SD K +E G+V +   +     Q   
Sbjct: 487  IGSYFGSVLCSVDVDKDTITDVLLVGAPMYM---SDLKKEE-GRVYLFTIKEGILGQHQF 542

Query: 361  LNGFEVF--ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPS 418
            L G E     RFGSAIA L D++ DGFND+ + +P   ++  G VYI+NG    +    S
Sbjct: 543  LEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQN-SGAVYIYNGHQGTIRTKYS 601

Query: 419  Q-ILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGL 477
            Q IL    A RS    FG S+ G  D++ +   D+ +GAFG  + +   ++ +  V    
Sbjct: 602  QKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFG--QVVQLWSQSIADVAIEA 659

Query: 478  EVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQKG 536
               P  +   NK   +    LK+ CF+ +F          P K N QV ++ +  L   G
Sbjct: 660  SFTPEKITLVNKNAQI---ILKL-CFSAKF---------RPTKQNNQVAIVYNITLDADG 706

Query: 537  ----AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYR 592
                   R LF  +      KNM +++     C E I Y+++ S+  + L       + R
Sbjct: 707  FSSRVTSRGLFKENNERCLQKNMVVNQA--QSCPEHIIYIQEPSDVVNSL-------DLR 757

Query: 593  LDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKL-----EVSVDSDQKKI 647
            +D   + +  G  P L  ++            DCGED +C   L     ++    +Q  I
Sbjct: 758  VD--ISLENPGTSPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFI 815

Query: 648  YIGDDNPLTLIVKAQNQGEGAYEAELIVSIP---LQADFIGVVRNNEALARLSCAFKTEN 704
                +  LT  V  +N+ E AY   ++V        A F   V   E   +++ + K+  
Sbjct: 816  VSNQNKRLTFSVTLKNKRESAYNTGIVVDFSENLFFASFSLPVDGTEVTCQVAASQKS-- 873

Query: 705  QTRQVVCDLGNP-MKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHK 763
                V CD+G P +K   Q+   + F  + Q+  + +      +  S   +K   +V+ K
Sbjct: 874  ----VACDVGYPALKREQQVTFTINFDFNLQNLQNQASLSFQALSESQEENKADNLVNLK 929

Query: 764  VDLAVLAAVEIRGVSSPDHIFLPIPNWEHKEN-PETEEDVGPVVQHIYELR---NNGPSS 819
            + L  L   EI    S +  F  I +  +  +   + EDVGP  + I+ L+    + P S
Sbjct: 930  IPL--LYDAEIHLTRSTNINFYEISSDGNVPSIVHSFEDVGP--KFIFSLKVTTGSVPVS 985

Query: 820  FSKAMLHLQWPYKYNNNTLLYILHYDID--GPMNCTSDMEINPLRIKISSLQTTEKNDTV 877
             +  ++H+   Y    N L+Y+     D  G ++C +D  INPL+I  +S   + K++  
Sbjct: 986  MATVIIHIP-QYTKEKNPLMYLTGVQTDKAGDISCNAD--INPLKIGQTSSSVSFKSENF 1042

Query: 878  AGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTET 937
                E                   L C  A C  + C +  +       + V + +W  T
Sbjct: 1043 RHTKE-------------------LNCRTASCSNVTCWLKDVHMKGEYFVNVTTRIWNGT 1083

Query: 938  FMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVI 997
            F +   Q    +++ +A+  +  +  +   IED T    VT  +          VP  VI
Sbjct: 1084 FASSTFQ----TVQLTAAAEINTYNPEIYVIEDNT----VTIPLMIMKPDEKAEVPTGVI 1135

Query: 998  ILAVLAGLLLLAVLVFVMYRMGFFKR-----VRPPQEEQEREQL 1036
            I +++AG+LLL  LV +++++GFFKR      + P E  E  +L
Sbjct: 1136 IGSIIAGILLLLALVAILWKLGFFKRKYEKMTKNPDEIDETTEL 1179



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 42/156 (26%), Positives = 65/156 (41%), Gaps = 18/156 (11%)

Query: 10  RLGPRGLPLLL----SGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMF 65
           R G   LPLLL    S  +L  C A+N+ +     +SGP    FG+AV  F+    +  +
Sbjct: 5   RTGAAPLPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGN--W 62

Query: 66  LLVGAPKANTTQPGIVEGGQVLKCDWS-STRRCQPIEFDATGNRDYAKDDPLEFKSHQWF 124
           LLVG+P +   +  +   G V KC    ST  C+ +    +     +  +  E K++   
Sbjct: 63  LLVGSPWSGFPENRM---GDVYKCPVDLSTATCEKLNLQTS----TSIPNVTEMKTNMSL 115

Query: 125 GASVRSKQDK--ILACAPLYHWRTEMKQEREPVGTC 158
           G  +         L C PL  W  +   +    G C
Sbjct: 116 GLILTRNMGTGGFLTCGPL--WAQQCGNQYYTTGVC 149


>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
          Length = 1188

 Score =  171 bits (434), Expect = 3e-42
 Identities = 211/892 (23%), Positives = 359/892 (40%), Gaps = 120/892 (13%)

Query: 181  GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLAT 240
            G    Q GFS    + D VLLG  G++ W G ++ +  A  V     + Y  ++  +L  
Sbjct: 363  GLEMSQTGFSSHVVE-DGVLLGAVGAYDWNGAVLKETSAGKVIPLRES-YLKEFPEELKN 420

Query: 241  RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSL---YNF 297
              A       YLGY+V     +  G   +V+G PR   T G V ++   N  SL      
Sbjct: 421  HGA-------YLGYTVTSVVSSRQG-RVYVAGAPRFNHT-GKVILFTMHNNRSLTIHQAM 471

Query: 298  TGEQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSLQRASGDF 356
             G+Q+ +YFG  + + DI+GD   DV  +GAP++ + G +     V ++  +L   +G  
Sbjct: 472  RGQQIGSYFGSEITSVDIDGDGVTDVLLVGAPMYFNEGRERGKVYVYELRQNLFVYNG-- 529

Query: 357  QTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAV 416
             T K +     ARFGS+IA + DL+QD +ND+ + AP   ++  G +YIF+G    +   
Sbjct: 530  -TLKDSHSYQNARFGSSIASVRDLNQDSYNDVVVGAPL-EDNHAGAIYIFHGFRGSILKT 587

Query: 417  PSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAG 476
            P Q +     A  +   FG S+ G  D++++G  DL VGA G   A++  +RPV+ +NA 
Sbjct: 588  PKQRITASELATGL-QYFGCSIHGQLDLNEDGLIDLAVGALG--NAVILWSRPVVQINAS 644

Query: 477  LEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKG 536
            L   PS +N  ++ C   G     +C     C       + P      V +  +    + 
Sbjct: 645  LHFEPSKINIFHRDCKRSGR--DATCLAAFLCFTP--IFLAPHFQTTTVGIRYNATMDER 700

Query: 537  AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYR 596
                   L       +    +   G   CE +  ++ D +++   + P+T  +EY L   
Sbjct: 701  RYTPRAHLDEGGDRFTNRAVLLSSGQELCERINFHVLDTADY---VKPVTFSVEYSL--- 754

Query: 597  TAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSD------------- 643
               +     P+L+   P  +         C ED  C P L +   SD             
Sbjct: 755  ---EDPDHGPMLDDGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLR 811

Query: 644  -------------QKKIYIGDDNPLTLIVKA--QNQGEGAYEAELIVSIPLQADFIGVVR 688
                            ++I +     + V+A  +N+GE AY   L +S      F  +++
Sbjct: 812  KPAQDCSAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNISQSANLQFASLIQ 871

Query: 689  NNEALARLSCAFKTENQTRQVVCDLGNPM---KAGTQLLAGLRFSVH---QQSEMDTSVK 742
              ++   + C    E + ++ VC++  P    KA         FS        E++ +  
Sbjct: 872  KEDSDGSIECV-NEERRLQKQVCNVSYPFFRAKAKVAFRLDFEFSKSIFLHHLEIELAAG 930

Query: 743  FDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETE--E 800
             D   + S   D V+P+  H   L   A V     SS  H       +E K N   E  +
Sbjct: 931  SDSNERDSTKEDNVAPLRFH---LKYEADVLFTRSSSLSH-------YEVKPNSSLERYD 980

Query: 801  DVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINP 860
             +GP    I+ ++N G       M+ +  P    +   L  L   +    N + ++  N 
Sbjct: 981  GIGPPFSCIFRIQNLGLFPIHGMMMKITIPIATRSGNRLLKLRDFLTDEANTSCNIWGNS 1040

Query: 861  LRIKISSLQTTEKNDTVAGQGERDHLITKRDLAL---SEGDIHTLGCGVAQCLKIVCQVG 917
               + + ++   +          D +    ++ L    E + H LG    + LK +    
Sbjct: 1041 TEYRPTPVEEDLRRAPQLNHSNSDVVSINCNIRLVPNQEINFHLLGNLWLRSLKAL---- 1096

Query: 918  RLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLV 977
               + KS  + V + L        + Q HS  +         E P + +  E       +
Sbjct: 1097 ---KYKSMKIMVNAAL--------QRQFHSPFIFRE------EDPSRQIVFE-------I 1132

Query: 978  TTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQE 1029
            +    W        VP+W+I+ + L GLLLLA+LV  ++++GFF+  R  +E
Sbjct: 1133 SKQEDW-------QVPIWIIVGSTLGGLLLLALLVLALWKLGFFRSARRRRE 1177



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 40/149 (26%), Positives = 56/149 (37%), Gaps = 16/149 (10%)

Query: 13  PRGLPLLLSGLLLP-LCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAP 71
           PRGL +  +  L P     FN+D   P    G   ++FG+ V       S   +L+VGAP
Sbjct: 4   PRGLVVAWALSLWPGFTDTFNMDTRKPRVIPGSRTAFFGYTVQ--QHDISGNKWLVVGAP 61

Query: 72  KANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRS- 130
                  G  + G V KC       C  +             +  E K +   G S+ + 
Sbjct: 62  LETN---GYQKTGDVYKCP-VIHGNCTKLNLGRV-----TLSNVSERKDNMRLGLSLATN 112

Query: 131 -KQDKILACAPLYHWRTEMKQEREPVGTC 158
            K +  LAC+PL  W  E        G C
Sbjct: 113 PKDNSFLACSPL--WSHECGSSYYTTGMC 139


>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
          Length = 1152

 Score =  168 bits (426), Expect = 2e-41
 Identities = 204/861 (23%), Positives = 362/861 (42%), Gaps = 100/861 (11%)

Query: 186  QGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRT-AQ 244
            Q GFS   T ++  LL   GS+ W G +               +Y+ K  +     T   
Sbjct: 352  QEGFSAAIT-SNGPLLSTVGSYDWAGGVF--------------LYTSKEKSTFINMTRVD 396

Query: 245  AIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKN--MSSLYNFTGEQM 302
            +  +D+YLGY+ A+     + +   V G PR    +G+V ++        S  N  G Q+
Sbjct: 397  SDMNDAYLGYAAAI--ILRNRVQSLVLGAPRYQH-IGLVAMFRQNTGMWESNANVKGTQI 453

Query: 303  AAYFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVS-LQRASGDFQTTK 360
             AYFG S+ + D++ +   D V IGAP + ++   G      QVSV  L R    +Q   
Sbjct: 454  GAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGG------QVSVCPLPRGRARWQCDA 507

Query: 361  L---NGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS-TGLNAV 416
            +      + + RFG+A+  LGD++ D   D+AI AP G ED +G VY+F+G S +G++  
Sbjct: 508  VLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFHGTSGSGISPS 566

Query: 417  PSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAG 476
             SQ + G   +  +   FG S+ G  D+  +G  DL VGA G    +L R++PV+ V A 
Sbjct: 567  HSQRIAGSKLSPRL-QYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRSQPVLRVKAI 623

Query: 477  LEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQK 535
            +E  P  + ++   C+      K     VR CL    K    R    Q++ ++   L   
Sbjct: 624  MEFNPREVARNVFECNDQVVKGK-EAGEVRVCLHVQ-KSTRDRLREGQIQSVVTYDLALD 681

Query: 536  GAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDY 595
                 +  +++ + + ++  T   G    CE L   L +  E  D ++PI + + + L  
Sbjct: 682  SGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIE--DPVSPIVLRLNFSLVG 739

Query: 596  RTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNP 654
               +    L+P+L +      +       +CG DN+C+  L ++        + +G    
Sbjct: 740  TPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPRE 799

Query: 655  LTLIVKAQNQGEGAYEAELIVSIPLQADF--IGVVRNNEALA--RLSC--AFKTE--NQT 706
              + V  +N GE +Y  ++    PL   +  +  ++N  +    RL+C  A  TE     
Sbjct: 800  FNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGAL 859

Query: 707  RQVVCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPV---VSH 762
            +   C + +P+    +++   + F V  ++ +   +     + S N   + +     +  
Sbjct: 860  KSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLEL 919

Query: 763  KVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSK 822
             V  AV   V   GVS+    +L         N    E+   V+QH Y++ N G  S   
Sbjct: 920  PVKYAVYMVVTSHGVSTK---YL---------NFTASENTSRVMQHQYQVSNLGQRSLPI 967

Query: 823  AMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGE 882
            +++ L  P + N   +        D P                   Q T   +  +    
Sbjct: 968  SLVFLV-PVRLNQTVIW-------DRP-------------------QVTFSENLSSTCHT 1000

Query: 883  RDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKE 942
            ++ L +  D          + C +A C +I C +      +     +K  L  + ++ K 
Sbjct: 1001 KERLPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYI-KT 1059

Query: 943  NQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVL 1002
            + NH   + S+A     +  +  LP         V +     ++P  +P P+ +I+ + +
Sbjct: 1060 SHNH-LLIVSTAEILFNDSVFTLLP----GQGAFVRSQTETKVEPFEVPNPLPLIVGSSV 1114

Query: 1003 AGLLLLAVLVFVMYRMGFFKR 1023
             GLLLLA++   +Y++GFFKR
Sbjct: 1115 GGLLLLALITAALYKLGFFKR 1135



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 36/137 (26%), Positives = 54/137 (39%), Gaps = 23/137 (16%)

Query: 25  LPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGG 84
           L LC  FNLD ++   +       FG +V   V    SR  ++VGAP+         + G
Sbjct: 11  LTLCHGFNLDTENAMTFQ-ENARGFGQSV---VQLQGSR--VVVGAPQEIVAAN---QRG 61

Query: 85  QVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLE-FKSHQWFGASVRSKQDKILACAPLYH 143
            + +CD+ ST  C+PI              P+E          +  +   ++LAC P  H
Sbjct: 62  SLYQCDY-STGSCEPIRLQV----------PVEAVNMSLGLSLAATTSPPQLLACGPTVH 110

Query: 144 WRTEMKQEREPVGTCFL 160
                 +     G CFL
Sbjct: 111 --QTCSENTYVKGLCFL 125


>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
          Length = 1153

 Score =  167 bits (422), Expect = 6e-41
 Identities = 200/857 (23%), Positives = 358/857 (41%), Gaps = 91/857 (10%)

Query: 186  QGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRT-AQ 244
            Q GFS   T ++  LL   GS+ W G +               +Y+ K  +     T   
Sbjct: 352  QEGFSAAIT-SNGPLLSTVGSYDWAGGVF--------------LYTSKEKSTFINMTRVD 396

Query: 245  AIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKN--MSSLYNFTGEQM 302
            +  +D+YLGY+ A+     + +   V G PR    +G+V ++        S  N  G Q+
Sbjct: 397  SDMNDAYLGYAAAI--ILRNRVQSLVLGAPRYQH-IGLVAMFRQNTGMWESNANVKGTQI 453

Query: 303  AAYFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKL 361
             AYFG S+ + D++ +   D V IGAP + ++   G++           R   D      
Sbjct: 454  GAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGQRARWQCDAVLYGE 513

Query: 362  NGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS-TGLNAVPSQI 420
             G + + RFG+A+  LGD++ D   D+AI AP G ED +G VY+F+G S +G++   SQ 
Sbjct: 514  QG-QPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFHGTSGSGISPSHSQR 571

Query: 421  LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY 480
            + G   +  +   FG S+ G  D+  +G  DL VGA G    +L R++PV+ V A +E  
Sbjct: 572  IAGSKLSPRL-QYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRSQPVLRVKAIMEFN 628

Query: 481  PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQKGAIR 539
            P  + ++   C+      K     VR CL    K    R    Q++ ++   L       
Sbjct: 629  PREVARNVFECNDQVVKGK-EAGEVRVCLHVQ-KSTRDRLREGQIQSVVTYDLALDSGRP 686

Query: 540  RALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAA 599
             +  +++ + + ++  T   G    CE L   L +  E  D ++PI + + + L     +
Sbjct: 687  HSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIE--DPVSPIVLRLNFSLVGTPLS 744

Query: 600  DTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNPLTLI 658
                L+P+L +      +       +CG DN+C+  L ++        + +G      + 
Sbjct: 745  AFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPREFNVT 804

Query: 659  VKAQNQGEGAYEAELIVSIPLQADF--IGVVRNNEALA--RLSC--AFKTE--NQTRQVV 710
            V  +N GE +Y  ++    PL   +  +  ++N  +    RL+C  A  TE     +   
Sbjct: 805  VTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTS 864

Query: 711  CDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPV---VSHKVDL 766
            C + +P+    +++   + F V  ++ +   +     + S N   + +     +   V  
Sbjct: 865  CSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKY 924

Query: 767  AVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLH 826
            AV   V   GVS+    +L         N    E+   V+QH Y++ N G  S   +++ 
Sbjct: 925  AVYMVVTSHGVSTK---YL---------NFTASENTSRVMQHQYQVSNLGQRSLPISLVF 972

Query: 827  LQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHL 886
            L  P + N   +        D P                   Q T   +  +    ++ L
Sbjct: 973  LV-PVRLNQTVIW-------DRP-------------------QVTFSENLSSTCHTKERL 1005

Query: 887  ITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNH 946
             +  D          + C +A C +I C +      +     +K  L  + ++ K + NH
Sbjct: 1006 PSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYI-KTSHNH 1064

Query: 947  SYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLL 1006
               + S+A     +  +  LP         V +     ++P  +P P+ +I+ + + GLL
Sbjct: 1065 -LLIVSTAEILFNDSVFTLLP----GQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLL 1119

Query: 1007 LLAVLVFVMYRMGFFKR 1023
            LLA++   +Y++GFFKR
Sbjct: 1120 LLALITAALYKLGFFKR 1136



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 36/137 (26%), Positives = 54/137 (39%), Gaps = 23/137 (16%)

Query: 25  LPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGG 84
           L LC  FNLD ++   +       FG +V   V    SR  ++VGAP+         + G
Sbjct: 11  LTLCHGFNLDTENAMTFQ-ENARGFGQSV---VQLQGSR--VVVGAPQEIVAAN---QRG 61

Query: 85  QVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLE-FKSHQWFGASVRSKQDKILACAPLYH 143
            + +CD+ ST  C+PI              P+E          +  +   ++LAC P  H
Sbjct: 62  SLYQCDY-STGSCEPIRLQV----------PVEAVNMSLGLSLAATTSPPQLLACGPTVH 110

Query: 144 WRTEMKQEREPVGTCFL 160
                 +     G CFL
Sbjct: 111 --QTCSENTYVKGLCFL 125


>gi|34452173 integrin alpha X precursor [Homo sapiens]
          Length = 1163

 Score =  167 bits (422), Expect = 6e-41
 Identities = 217/882 (24%), Positives = 353/882 (40%), Gaps = 106/882 (12%)

Query: 186  QGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQA 245
            Q GFS  FT  D  +LG  GSF W G             Y PN+     N        + 
Sbjct: 353  QEGFSAVFTP-DGPVLGAVGSFTWSGGAFL---------YPPNMSPTFINMSQENVDMR- 401

Query: 246  IFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAART-LGMVYIYDGKNMSSLYNFTGEQMAA 304
               DSYLGYS  +  + G  +   V G PR   T   +++    +        TG Q+ +
Sbjct: 402  ---DSYLGYSTELALWKG--VQSLVLGAPRYQHTGKAVIFTQVSRQWRMKAEVTGTQIGS 456

Query: 305  YFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNG 363
            YFG S+ + D++ D   D V IGAP + ++   G++  V  +    +R   D       G
Sbjct: 457  YFGASLCSVDVDSDGSTDLVLIGAPHYYEQTRGGQVS-VCPLPRGWRRWWCDAVLYGEQG 515

Query: 364  FEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNG-RSTGLNAVPSQILE 422
               + RFG+A+  LGD++ D   D+ I AP G E+ +G VY+F+G     ++   SQ + 
Sbjct: 516  HP-WGRFGAALTVLGDVNGDKLTDVVIGAP-GEEENRGAVYLFHGVLGPSISPSHSQRIA 573

Query: 423  GQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPS 482
            G   + S    FG ++ G  D+ ++G  DL VGA G  + +L R RPV+ V   ++  P+
Sbjct: 574  GSQLS-SRLQYFGQALSGGQDLTQDGLVDLAVGARG--QVLLLRTRPVLWVGVSMQFIPA 630

Query: 483  ILNQDNKTCSLPGTALKVSCFNVRFCLKAD--GKGVLPRKLNFQVELLLDKLKQKGAIR- 539
             + +    C       + +      CL  D   K +L  + + Q  + LD     G +  
Sbjct: 631  EIPRSAFECR-EQVVSEQTLVQSNICLYIDKRSKNLLGSR-DLQSSVTLDLALDPGRLSP 688

Query: 540  RALFLYSRSPSHSKNMTISR----GGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDY 595
            RA F        +KN ++SR    G    CE     L   S   D +TPIT+ + + L  
Sbjct: 689  RATF------QETKNRSLSRVRVLGLKAHCENFNLLL--PSCVEDSVTPITLRLNFTLVG 740

Query: 596  RTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNP 654
            +       L+P+L        +       +CG D++C+  L +S      K + +G +  
Sbjct: 741  KPLLAFRNLRPMLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLE 800

Query: 655  LTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNE----ALARLSC--AFKTENQTRQ 708
            L   V   N GE +Y   +  S P    +  V    +        L+C  A      T  
Sbjct: 801  LNAEVMVWNDGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWS 860

Query: 709  VVCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLA 767
              C + + + + G Q+     F V  ++ +   +     + S N   + S   + +++L 
Sbjct: 861  TSCRINHLIFRGGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSK-TTFQLELP 919

Query: 768  VLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHL 827
            V  AV    V S    F    N+      E+EE    V  H Y++ N G        ++ 
Sbjct: 920  VKYAVYT--VVSSHEQFTKYLNFS-----ESEEKESHVAMHRYQVNNLGQRDL-PVSINF 971

Query: 828  QWPYKYNNNTLLYILHYDIDGPMN----CTSDMEINPLRIKISSLQTTEKNDTVAGQGER 883
              P + N   +   +  ++  P N    C+S+    P    ++ +Q   KN         
Sbjct: 972  WVPVELNQEAVW--MDVEVSHPQNPSLRCSSEKIAPPASDFLAHIQ---KNP-------- 1018

Query: 884  DHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLL---WTETFMN 940
                              L C +A CL+  C V      +     +K  L   W    + 
Sbjct: 1019 -----------------VLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQ 1061

Query: 941  KENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILA 1000
            K+      S+ S A        Y  LP ++      +    T  ++   +  P  +I+ +
Sbjct: 1062 KK-----VSVVSVAEITFDTSVYSQLPGQE----AFMRAQTTTVLEKYKVHNPTPLIVGS 1112

Query: 1001 VLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENG 1042
             + GLLLLA++  V+Y++GFFKR      E+   Q+ P ENG
Sbjct: 1113 SIGGLLLLALITAVLYKVGFFKRQYKEMMEEANGQIAP-ENG 1153


>gi|148728188 integrin, alpha E precursor [Homo sapiens]
          Length = 1179

 Score =  159 bits (402), Expect = 1e-38
 Identities = 148/517 (28%), Positives = 226/517 (43%), Gaps = 52/517 (10%)

Query: 178 DADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQ 237
           DA      Q GFS       +VLLG  G+F W G  +          YD      ++ NQ
Sbjct: 395 DALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALL---------YDTRSRRGRFLNQ 445

Query: 238 LATRTAQA-IFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIY-DGKNMSSLY 295
            A   A A     SYLGY+VAV   +      +++G PR      +  +  +G+  S L 
Sbjct: 446 TAAAAADAEAAQYSYLGYAVAV--LHKTCSLSYIAGAPRYKHHGAVFELQKEGREASFLP 503

Query: 296 NFTGEQMAAYFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVSLQRASG 354
              GEQM +YFG  +   DI+ D   D + + AP +   G +G++         L    G
Sbjct: 504 VLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEGRVYVY-----RLSEQDG 558

Query: 355 DFQTTK-LNGFEVF--ARFGSAIAPLGDLDQDGFNDIAIAAP---YGGED--KKGIVYIF 406
            F   + L+G   F  ARFG A+A +GDL QD   D+AI AP   +G +D    G VYI+
Sbjct: 559 SFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIY 618

Query: 407 NGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYR 466
           NG   GL+A PSQ +     A  +   FG SM G  DI  +G  D+ VG  G  +A+++R
Sbjct: 619 NGHWDGLSASPSQRIRASTVAPGL-QYFGMSMAGGFDISGDGLADITVGTLG--QAVVFR 675

Query: 467 ARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVE 526
           +RPV+ +   +   PS L          G      CF +     A   G+    LNF ++
Sbjct: 676 SRPVVRLKVSMAFTPSAL-----PIGFNGVVNVRLCFEISSVTTASESGLREALLNFTLD 730

Query: 527 LLLDKLKQK---GAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEF--RDK 581
           + + K +++     +R  L       S          G   CE+L+  +  E E    D 
Sbjct: 731 VDVGKQRRRLQCSDVRSCLGCLREWSS----------GSQLCEDLL-LMPTEGELCEEDC 779

Query: 582 LTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD 641
            +  ++ + Y+L       T   QPIL+++T      Q      C     C  +L+++  
Sbjct: 780 FSNASVKVSYQLQ-TPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLATT 838

Query: 642 SDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIP 678
             Q+++ +G    LTL +   N GE +Y   + ++ P
Sbjct: 839 VSQQELVVGLTKELTLNINLTNSGEDSYMTSMALNYP 875



 Score = 31.2 bits (69), Expect = 5.3
 Identities = 12/28 (42%), Positives = 21/28 (75%)

Query: 996  VIILAVLAGLLLLAVLVFVMYRMGFFKR 1023
            +II   + GLL+L V++ ++++ GFFKR
Sbjct: 1127 IIIKGSVGGLLVLIVILVILFKCGFFKR 1154


>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
          Length = 1167

 Score =  149 bits (377), Expect = 1e-35
 Identities = 155/553 (28%), Positives = 253/553 (45%), Gaps = 54/553 (9%)

Query: 181 GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLAT 240
           G    Q GFS    K D +L G  G++ W G ++     E   +  P   +++     A 
Sbjct: 369 GLEMSQIGFSTHRLK-DGILFGMVGAYDWGGSVLW---LEGGHRLFPPRMALEDEFPPAL 424

Query: 241 RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSL---YNF 297
           +   A     YLGYSV+     G G   F+SG PR  R  G V  +  K   ++    + 
Sbjct: 425 QNHAA-----YLGYSVSSMLLRG-GRRLFLSGAPRF-RHRGKVIAFQLKKDGAVRVAQSL 477

Query: 298 TGEQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSL--QRASG 354
            GEQ+ +YFG  +   D + D   DV  + AP+F+  G   K  E G+V V L  Q++  
Sbjct: 478 QGEQIGSYFGSELCPLDTDRDGTTDVLLVAAPMFL--GPQNK--ETGRVYVYLVGQQSLL 533

Query: 355 DFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLN 414
             Q T        ARFG A+  L DL+QDGF D+A+ AP   +  +G +Y+++G  +G+ 
Sbjct: 534 TLQGTLQPEPPQDARFGFAMGALPDLNQDGFADVAVGAPL-EDGHQGALYLYHGTQSGVR 592

Query: 415 AVPSQILEGQWAARSMPPS---FGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVI 471
             P+Q +    AA SMP +   FG S+ G  D+D +   D+ VGA G   AIL  +RP++
Sbjct: 593 PHPAQRI----AAASMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGA--AILLSSRPIV 646

Query: 472 TVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVEL-LLD 530
            +   LEV P  ++   + C   G   +  C     C +   +   P + + Q  +    
Sbjct: 647 HLTPSLEVTPQAISVVQRDCRRRGQ--EAVCLTAALCFQVTSR--TPGRWDHQFYMRFTA 702

Query: 531 KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFME 590
            L +  A  RA F  S      + + +S G  + CE+L  ++ D S++   L P+ + + 
Sbjct: 703 SLDEWTAGARAAFDGSGQRLSPRRLRLSVGN-VTCEQLHFHVLDTSDY---LRPVALTVT 758

Query: 591 YRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSD----QKK 646
           + LD     +TT   P+LN+ +P +I +      DCG DN C   L + V+ D    +K 
Sbjct: 759 FALD-----NTTKPGPVLNEGSPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKA 813

Query: 647 IYI--GDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTEN 704
            ++  G    + +    +N+ E AY   L +          +    E+  ++ CA  + +
Sbjct: 814 PFVVRGGRRKVLVSTTLENRKENAYNTSLSLIFSRNLHLASLTPQRESPIKVECAAPSAH 873

Query: 705 QTRQVVCDLGNPM 717
                +C +G+P+
Sbjct: 874 AR---LCSVGHPV 883



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 36/130 (27%), Positives = 70/130 (53%), Gaps = 7/130 (5%)

Query: 908  QCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLP 967
            QC  + C +G+L +G    + +  L+  E F   +        KS    +  E   +   
Sbjct: 1044 QCQVVRCHLGQLAKGTEVSVGLLRLVHNEFFRRAK-------FKSLTVVSTFELGTEEGS 1096

Query: 968  IEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPP 1027
            +  +T ++  + ++   +Q  P+ + +W++I +VL GLLLLA+LVF ++++GFF   + P
Sbjct: 1097 VLQLTEASRWSESLLEVVQTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIP 1156

Query: 1028 QEEQEREQLQ 1037
            +EE+  E+L+
Sbjct: 1157 EEEKREEKLE 1166



 Score = 35.0 bits (79), Expect = 0.37
 Identities = 34/127 (26%), Positives = 46/127 (36%), Gaps = 9/127 (7%)

Query: 16  LPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANT 75
           LPL+    L  LC  FNLD   P  + GP  + FG++V   V     + ++LVGAP    
Sbjct: 11  LPLVF---LTGLCSPFNLDEHHPRLFPGPPEAEFGYSVLQHV--GGGQRWMLVGAP---W 62

Query: 76  TQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKI 135
             P     G V +C         P      G+             H              
Sbjct: 63  DGPSGDRRGDVYRCPVGGAHNA-PCAKGHLGDYQLGNSSHPAVNMHLGMSLLETDGDGGF 121

Query: 136 LACAPLY 142
           +ACAPL+
Sbjct: 122 MACAPLW 128


>gi|62548866 integrin, alpha D precursor [Homo sapiens]
          Length = 1161

 Score =  147 bits (370), Expect = 7e-35
 Identities = 205/862 (23%), Positives = 356/862 (41%), Gaps = 107/862 (12%)

Query: 186  QGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQA 245
            Q GFS   T  D + LG  GSF W G             Y PN+     N        + 
Sbjct: 352  QEGFSTALTM-DGLFLGAVGSFSWSGGAFL---------YPPNMSPTFINMSQENVDMR- 400

Query: 246  IFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAART-LGMVYIYDGKNMSSLYNFTGEQMAA 304
               DSYLGYS  +  + G  + + V G PR   T   +++    +        TG Q+ +
Sbjct: 401  ---DSYLGYSTELALWKG--VQNLVLGAPRYQHTGKAVIFTQVSRQWRKKAEVTGTQIGS 455

Query: 305  YFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVS-LQRASGDFQTTKLN 362
            YFG S+ + D++ D   D + IGAP + ++   G      QVSV  L R    +Q   + 
Sbjct: 456  YFGASLCSVDVDSDGSTDLILIGAPHYYEQTRGG------QVSVCPLPRGRVQWQCDAVL 509

Query: 363  GFEV---FARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS-TGLNAVPS 418
              E    + RFG+A+  LGD+++D   D+AI AP G ++ +G VY+F+G S +G++   S
Sbjct: 510  RGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAP-GEQENRGAVYLFHGASESGISPSHS 568

Query: 419  Q-ILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGL 477
            Q I   Q + R     FG ++ G  D+ ++G  DL VGA G  + +L R+ PV+ V   +
Sbjct: 569  QRIASSQLSPRLQ--YFGQALSGGQDLTQDGLMDLAVGARG--QVLLLRSLPVLKVGVAM 624

Query: 478  EVYPSILNQDNKTC-SLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKG 536
               P  + +    C     +AL+    +   CL    K  L +  + Q  +  D     G
Sbjct: 625  RFSPVEVAKAVYRCWEEKPSALEAG--DATVCLTIQ-KSSLDQLGDIQSSVRFDLALDPG 681

Query: 537  AI-RRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDY 595
             +  RA+F  +++P+ ++  T+  G  + CE L   L D  E  D ++PI + + + L  
Sbjct: 682  RLTSRAIFNETKNPTLTRRKTLGLG--IHCETLKLLLPDCVE--DVVSPIILHLNFSLVR 737

Query: 596  RTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNP 654
                    L+P+L   +    +       +CG+D +C+  L V++  S  + + +G    
Sbjct: 738  EPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTLSFSGLQTLTVGSSLE 797

Query: 655  LTLIVKAQNQGEGAYEAELIVSIPLQADFIGV----VRNNEALARLSC-AFKTENQ-TRQ 708
            L +IV   N GE +Y   + +  P       V     + +++  RL+C    TE++  R 
Sbjct: 798  LNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRS 857

Query: 709  VVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAV 768
              C + +P+              H+ S     V FD+  +++         +  ++ +  
Sbjct: 858  SRCSVNHPI-------------FHEGSNGTFIVTFDVSYKAT---------LGDRMLMRA 895

Query: 769  LAAVEIRGVSSPDHIF---LPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAML 825
             A+ E    SS    F   LP+    +      EE              N  +S  K M 
Sbjct: 896  SASSENNKASSSKATFQLELPVKYAVYTMISRQEESTKYF---------NFATSDEKKMK 946

Query: 826  HLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKN-DTVAGQGERD 884
              +  Y+ NN     +   D+   +N    + +N + +    ++   ++   V+ +    
Sbjct: 947  EAEHRYRVNN-----LSQRDLAISINFWVPVLLNGVAVWDVVMEAPSQSLPCVSERKPPQ 1001

Query: 885  HLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLL---WTETFMNK 941
            H     D          L C +A CL+  C V      +     +K  L   W    + K
Sbjct: 1002 H----SDFLTQISRSPMLDCSIADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQK 1057

Query: 942  ENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAV 1001
            +       + S A        Y  LP ++      +   +   ++   +   + +I+ + 
Sbjct: 1058 K-----VLVVSVAEITFDTSVYSQLPGQE----AFMRAQMEMVLEEDEVYNAIPIIMGSS 1108

Query: 1002 LAGLLLLAVLVFVMYRMGFFKR 1023
            +  LLLLA++   +Y++GFFKR
Sbjct: 1109 VGALLLLALITATLYKLGFFKR 1130



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 39/133 (29%), Positives = 54/133 (40%), Gaps = 29/133 (21%)

Query: 15  GLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAP--- 71
           G  LLLS  +L     FNLDV+ P  +    G +    V F      SR  L+VGAP   
Sbjct: 4   GTVLLLS--VLASYHGFNLDVEEPTIFQEDAGGFGQSVVQF----GGSR--LVVGAPLEV 55

Query: 72  -KANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRS 130
             AN T       G++  C  ++T  CQPI         + + + +         AS   
Sbjct: 56  VAANQT-------GRLYDCA-AATGMCQPIPL-------HIRPEAVNMSLGLTLAASTNG 100

Query: 131 KQDKILACAPLYH 143
              ++LAC P  H
Sbjct: 101 --SRLLACGPTLH 111


>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
          Length = 1086

 Score =  123 bits (308), Expect = 1e-27
 Identities = 152/602 (25%), Positives = 254/602 (42%), Gaps = 65/602 (10%)

Query: 175 QDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKY 234
           QD+ +        G S D ++   V+ G  G+  W G  +     ++ +    + +    
Sbjct: 257 QDLTSFNMELSSSGISADLSRGHAVV-GAVGAKDWAGGFL-----DLKADLQDDTF---I 307

Query: 235 NNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYD----GKN 290
            N+  T   +A     YLGY+V     +        SG PR    +G V ++     G +
Sbjct: 308 GNEPLTPEVRA----GYLGYTVTWLP-SRQKTSLLASGAPRYQH-MGRVLLFQEPQGGGH 361

Query: 291 MSSLYNFTGEQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSL 349
            S +    G Q+ +YFG  +   D++ D   ++  IGAPLF         Q  G+V +  
Sbjct: 362 WSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGE------QRGGRVFIYQ 415

Query: 350 QRASGDFQTTKLNGFEVF--ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFN 407
           +R  G  + ++L G   +   RFG AI  L D++ DG  D+A+ AP    +++G VYIFN
Sbjct: 416 RRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFN 472

Query: 408 GRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRA 467
           GR  GL+  PSQ +EG      +   FG S+ G  D++ +G  D+ VGA    + I+  +
Sbjct: 473 GRHGGLSPQPSQRIEGTQVLSGI-QWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSS 529

Query: 468 RPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVEL 527
           RPV+ +   +   P+ +      CS   +       N+  C +   K ++P+     V  
Sbjct: 530 RPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQI--KSLIPQFQGRLVAN 587

Query: 528 LLDKLKQKG--AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPI 585
           L   L+  G    RR LF   R   H     I+    M C +   +       +D ++PI
Sbjct: 588 LTYTLQLDGHRTRRRGLFPGGR---HELRRNIAVTTSMSCTDFSFHF--PVCVQDLISPI 642

Query: 586 TIFMEYRL--------DYRTAADTTGLQPILNQFTPANISRQAHILLD--CGEDNVCKPK 635
            + + + L        D R   D   + PIL    P+  S    I  +  CGED  C+  
Sbjct: 643 NVSLNFSLWEEEGTPRDQRAGKD---IPPILR---PSLHSETWEIPFEKNCGEDKKCEAN 696

Query: 636 LEVSVD-SDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGV-VRNNEAL 693
           L VS   +  + + +     L++ +   N  E AY  +L +  P    F  V +    + 
Sbjct: 697 LRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQ 756

Query: 694 ARLSCAFKTENQ---TRQVVCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQS 749
             +SC    E     +R + C++ +P+ KAG  +   + F+    S    SV+    +  
Sbjct: 757 IPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTC 816

Query: 750 SN 751
           +N
Sbjct: 817 NN 818



 Score = 34.3 bits (77), Expect = 0.63
 Identities = 13/30 (43%), Positives = 24/30 (80%)

Query: 994  VWVIILAVLAGLLLLAVLVFVMYRMGFFKR 1023
            +++ +L+ + GLLLL ++  V+Y++GFFKR
Sbjct: 1006 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKR 1035


>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
          Length = 1170

 Score =  121 bits (304), Expect = 3e-27
 Identities = 152/602 (25%), Positives = 254/602 (42%), Gaps = 64/602 (10%)

Query: 175 QDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKY 234
           QD+ +        G S D ++   V+ G  G+  W G  +     ++ +    + +    
Sbjct: 340 QDLTSFNMELSSSGISADLSRGHAVV-GAVGAKDWAGGFL-----DLKADLQDDTF---I 390

Query: 235 NNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYD----GKN 290
            N+  T   +A     YLGY+V     +        SG PR    +G V ++     G +
Sbjct: 391 GNEPLTPEVRA----GYLGYTVTWLP-SRQKTSLLASGAPRYQH-MGRVLLFQEPQGGGH 444

Query: 291 MSSLYNFTGEQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSL 349
            S +    G Q+ +YFG  +   D++ D   ++  IGAPLF         Q  G+V +  
Sbjct: 445 WSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGE------QRGGRVFIYQ 498

Query: 350 QRASGDFQTTKLNGFEVF--ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFN 407
           +R  G  + ++L G   +   RFG AI  L D++ DG  D+A+ AP    +++G VYIFN
Sbjct: 499 RRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFN 555

Query: 408 GRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRA 467
           GR  GL+  PSQ +EG      +   FG S+ G  D++ +G  D+ VGA    + I+  +
Sbjct: 556 GRHGGLSPQPSQRIEGTQVLSGI-QWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSS 612

Query: 468 RPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVEL 527
           RPV+ +   +   P+ +      CS   +       N+  C +   K ++P+     V  
Sbjct: 613 RPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQI--KSLIPQFQGRLVAN 670

Query: 528 LLDKLKQKG--AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPI 585
           L   L+  G    RR LF   R   H     I+    M C +   +       +D ++PI
Sbjct: 671 LTYTLQLDGHRTRRRGLFPGGR---HELRRNIAVTTSMSCTDFSFHF--PVCVQDLISPI 725

Query: 586 TIFMEYRL--------DYRTAADTTGLQPILNQFTPANISRQAHILLD--CGEDNVCKPK 635
            + + + L        D R  A    + PIL    P+  S    I  +  CGED  C+  
Sbjct: 726 NVSLNFSLWEEEGTPRDQR--AQGKDIPPILR---PSLHSETWEIPFEKNCGEDKKCEAN 780

Query: 636 LEVSVD-SDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGV-VRNNEAL 693
           L VS   +  + + +     L++ +   N  E AY  +L +  P    F  V +    + 
Sbjct: 781 LRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQ 840

Query: 694 ARLSCAFKTENQ---TRQVVCDLGNPM-KAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQS 749
             +SC    E     +R + C++ +P+ KAG  +   + F+    S    SV+    +  
Sbjct: 841 IPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTC 900

Query: 750 SN 751
           +N
Sbjct: 901 NN 902



 Score = 34.3 bits (77), Expect = 0.63
 Identities = 13/30 (43%), Positives = 24/30 (80%)

Query: 994  VWVIILAVLAGLLLLAVLVFVMYRMGFFKR 1023
            +++ +L+ + GLLLL ++  V+Y++GFFKR
Sbjct: 1090 LYLYVLSGIGGLLLLLLIFIVLYKVGFFKR 1119


>gi|29171717 glycosylphosphatidylinositol specific phospholipase D1
           isoform 1 precursor [Homo sapiens]
          Length = 840

 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 55/221 (24%), Positives = 104/221 (47%), Gaps = 29/221 (13%)

Query: 253 GYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYF------ 306
           G   +V  +  D +      + R  RT+       G  +S  +      +A+YF      
Sbjct: 326 GVFFSVNSWTPDSMSFIYKALERNIRTM----FIGGSQLSQKH--VSSPLASYFLSFPYA 379

Query: 307 --GFSVAATDINGDDYADVFIGAPLFMDRG--SDGKLQEVGQVSVSLQRASGDFQTTK-- 360
             G+++ + D+N D + D+ +GAP +   G    G++  +    + L     D       
Sbjct: 380 RLGWAMTSADLNQDGHGDLVVGAPGYSRPGHIHIGRVYLIYGNDLGLPPVDLDLDKEAHR 439

Query: 361 -LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDK---KGIVYI-FNGRSTGLNA 415
            L GF+   RFGSA+A L D + DG  D+A+ AP  G ++   KG VY+ F  +  G+++
Sbjct: 440 ILEGFQPSGRFGSALAVL-DFNVDGVPDLAVGAPSVGSEQLTYKGAVYVYFGSKQGGMSS 498

Query: 416 VPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGA 456
            P+  +    + + +  + G+++  A D++ +  PDL++G+
Sbjct: 499 SPNITI----SCQDIYCNLGWTLL-AADVNGDSEPDLVIGS 534



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 56/218 (25%), Positives = 91/218 (41%), Gaps = 27/218 (12%)

Query: 247 FDDSYLGYSVAVGDFNGDGIDDFVSGVPRAART----LGMVYIYDGKNM----------- 291
           F  + LG+++   D N DG  D V G P  +R     +G VY+  G ++           
Sbjct: 376 FPYARLGWAMTSADLNQDGHGDLVVGAPGYSRPGHIHIGRVYLIYGNDLGLPPVDLDLDK 435

Query: 292 SSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQR 351
            +     G Q +  FG ++A  D N D   D+ +GAP     GS+ +L   G V V    
Sbjct: 436 EAHRILEGFQPSGRFGSALAVLDFNVDGVPDLAVGAP---SVGSE-QLTYKGAVYVYFGS 491

Query: 352 ASGDFQTT---KLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPY--GGEDKKGIVYIF 406
             G   ++    ++  +++   G  +    D++ D   D+ I +P+  GG  +KGIV  F
Sbjct: 492 KQGGMSSSPNITISCQDIYCNLGWTLL-AADVNGDSEPDLVIGSPFAPGGGKQKGIVAAF 550

Query: 407 NGRSTGLNAVPSQILEGQWAARSMPPS--FGYSMKGAT 442
               +  +     +    W  R       FGYS+ G T
Sbjct: 551 YSGPSLSDKEKLNVEAANWTVRGEEDFSWFGYSLHGVT 588



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 48/159 (30%), Positives = 77/159 (48%), Gaps = 32/159 (20%)

Query: 278 RTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDI--NGDDYADVFIGAPLFMDRGS 335
           ++LG VY Y   N  S +  +G++     G S+++  +  NG     + +GAP + D   
Sbjct: 619 KSLGRVYGYFPPNGQSWFTISGDKAMGKLGTSLSSGHVLMNGTLKQVLLVGAPTYDD--- 675

Query: 336 DGKLQEVGQVSVSLQRA--------SGDFQTTKLNGFEV---FARFGSAIAPLGDLDQDG 384
              + +V  ++V+L +         + D Q   L+ F     F+RFG  +  L DLD DG
Sbjct: 676 ---VSKVAFLTVTLHQGGATRMYALTSDAQPLLLSTFSGDRRFSRFGGVLH-LSDLDDDG 731

Query: 385 FNDIAIAAP----------YGGEDKKGIVYIFNGRSTGL 413
            ++I +AAP           GGED  G VY++NG+ T L
Sbjct: 732 LDEIIMAAPLRIADVTSGLIGGED--GRVYVYNGKETTL 768



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 34/99 (34%), Positives = 45/99 (45%), Gaps = 9/99 (9%)

Query: 239 ATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTL----GMVYIYDGKN---M 291
           A R  +        G ++AV DFN DG+ D   G P          G VY+Y G     M
Sbjct: 437 AHRILEGFQPSGRFGSALAVLDFNVDGVPDLAVGAPSVGSEQLTYKGAVYVYFGSKQGGM 496

Query: 292 SSLYNFTGEQMAAY--FGFSVAATDINGDDYADVFIGAP 328
           SS  N T      Y   G+++ A D+NGD   D+ IG+P
Sbjct: 497 SSSPNITISCQDIYCNLGWTLLAADVNGDSEPDLVIGSP 535


>gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo
            sapiens]
          Length = 462

 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 92/454 (20%), Positives = 168/454 (37%), Gaps = 56/454 (12%)

Query: 625  DCGEDNVCKPKLEVSVD-SDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADF 683
            +CG D++C+  L +S      K + +G +  L   V   N GE +Y   +  S P    +
Sbjct: 19   NCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGLSY 78

Query: 684  IGVVRNNEA----LARLSC--AFKTENQTRQVVCDLGNPM-KAGTQLLAGLRFSVHQQSE 736
              V    +        L+C  A      T    C + + + + G Q+     F V  ++ 
Sbjct: 79   RYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQITFLATFDVSPKAV 138

Query: 737  MDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENP 796
            +   +     + S N   + S   + +++L V  AV    V S    F    N+      
Sbjct: 139  LGDRLLLTANVSSENNTPRTSKT-TFQLELPVKYAVYT--VVSSHEQFTKYLNFS----- 190

Query: 797  ETEEDVGPVVQHIYELRNNGPSSFS----------KAMLHLQWPYKYNNNTL-------- 838
            E+EE    V  H Y+        ++             ++   P + N   +        
Sbjct: 191  ESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQEAVWMDVEVSH 250

Query: 839  -------LYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRD 891
                   +++LH +    ++    M +  +  +   L    +N ++    E+        
Sbjct: 251  PQVPKDCMWLLH-ECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCSSEKIAPPASDF 309

Query: 892  LALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLL---WTETFMNKENQNHSY 948
            LA  + +   L C +A CL+  C V      +     +K  L   W    + K+      
Sbjct: 310  LAHIQKN-PVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKK-----V 363

Query: 949  SLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLL 1008
            S+ S A        Y  LP ++      +    T  ++   +  P  +I+ + + GLLLL
Sbjct: 364  SVVSVAEITFDTSVYSQLPGQE----AFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLL 419

Query: 1009 AVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENG 1042
            A++  V+Y++GFFKR      E+   Q+ P ENG
Sbjct: 420  ALITAVLYKVGFFKRQYKEMMEEANGQIAP-ENG 452


>gi|31881770 ADAM metallopeptidase domain 30 preproprotein [Homo
            sapiens]
          Length = 790

 Score = 31.6 bits (70), Expect = 4.1
 Identities = 13/47 (27%), Positives = 26/47 (55%)

Query: 984  GIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEE 1030
            G+    +P  +WV+ + +   +LL+  +VFV +R      ++P QE+
Sbjct: 676  GLLRGAIPSSIWVVSIIMFRLILLILSVVFVFFRQVIGNHLKPKQEK 722


>gi|8393638 F11 receptor precursor [Homo sapiens]
          Length = 299

 Score = 31.2 bits (69), Expect = 5.3
 Identities = 20/54 (37%), Positives = 26/54 (48%), Gaps = 3/54 (5%)

Query: 994  VWVIILAVLAGLLLLAVLVF---VMYRMGFFKRVRPPQEEQEREQLQPHENGEG 1044
            V VI+ AVL  L+LL +LVF     Y  G F R +     ++    QP    EG
Sbjct: 236  VGVIVAAVLVTLILLGILVFGIWFAYSRGHFDRTKKGTSSKKVIYSQPSARSEG 289


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,652,132
Number of Sequences: 37866
Number of extensions: 1890806
Number of successful extensions: 4033
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 3640
Number of HSP's gapped (non-prelim): 67
length of query: 1048
length of database: 18,247,518
effective HSP length: 113
effective length of query: 935
effective length of database: 13,968,660
effective search space: 13060697100
effective search space used: 13060697100
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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