Search of human proteins with 4504351

Search of human proteins with 4504351

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504351 delta globin [Homo sapiens]
         (147 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504351 delta globin [Homo sapiens]                                302   6e-83
gi|4504349 beta globin [Homo sapiens]                                 284   2e-77
gi|4885393 epsilon globin [Homo sapiens]                              232   1e-61
gi|6715607 G-gamma globin [Homo sapiens]                              228   1e-60
gi|28302131 A-gamma globin [Homo sapiens]                             225   1e-59
gi|4504347 alpha 1 globin [Homo sapiens]                              113   7e-26
gi|4504345 alpha 2 globin [Homo sapiens]                              113   7e-26
gi|4885397 hemoglobin, zeta [Homo sapiens]                            101   2e-22
gi|4885395 theta 1 globin [Homo sapiens]                               95   2e-20
gi|51510893 hemoglobin mu chain [Homo sapiens]                         85   2e-17
gi|19549331 cytoglobin [Homo sapiens]                                  69   1e-12
gi|10864065 neuroglobin [Homo sapiens]                                 37   0.008
gi|46397369 leucine rich repeat containing 20 isoform 1 [Homo sa...    28   3.6  
gi|167466264 leucine rich repeat containing 18 [Homo sapiens]          27   8.0  

>gi|4504351 delta globin [Homo sapiens]
          Length = 147

 Score =  302 bits (774), Expect = 6e-83
 Identities = 147/147 (100%), Positives = 147/147 (100%)

Query: 1   MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK 60
           MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK
Sbjct: 1   MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK 60

Query: 61  VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG 120
           VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG
Sbjct: 61  VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG 120

Query: 121 KEFTPQMQAAYQKVVAGVANALAHKYH 147
           KEFTPQMQAAYQKVVAGVANALAHKYH
Sbjct: 121 KEFTPQMQAAYQKVVAGVANALAHKYH 147


>gi|4504349 beta globin [Homo sapiens]
          Length = 147

 Score =  284 bits (727), Expect = 2e-77
 Identities = 137/147 (93%), Positives = 142/147 (96%)

Query: 1   MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK 60
           MVHLTPEEK+AV ALWGKVNVD VGGEALGRLLVVYPWTQRFFESFGDLS+PDAVMGNPK
Sbjct: 1   MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK 60

Query: 61  VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG 120
           VKAHGKKVLGAFSDGLAHLDNLKGTF+ LSELHCDKLHVDPENFRLLGNVLVCVLA +FG
Sbjct: 61  VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFG 120

Query: 121 KEFTPQMQAAYQKVVAGVANALAHKYH 147
           KEFTP +QAAYQKVVAGVANALAHKYH
Sbjct: 121 KEFTPPVQAAYQKVVAGVANALAHKYH 147


>gi|4885393 epsilon globin [Homo sapiens]
          Length = 147

 Score =  232 bits (591), Expect = 1e-61
 Identities = 107/147 (72%), Positives = 129/147 (87%)

Query: 1   MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK 60
           MVH T EEK AV +LW K+NV+  GGEALGRLLVVYPWTQRFF+SFG+LSSP A++GNPK
Sbjct: 1   MVHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGNPK 60

Query: 61  VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG 120
           VKAHGKKVL +F D + ++DNLK  F++LSELHCDKLHVDPENF+LLGNV+V +LA +FG
Sbjct: 61  VKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFG 120

Query: 121 KEFTPQMQAAYQKVVAGVANALAHKYH 147
           KEFTP++QAA+QK+V+ VA ALAHKYH
Sbjct: 121 KEFTPEVQAAWQKLVSAVAIALAHKYH 147


>gi|6715607 G-gamma globin [Homo sapiens]
          Length = 147

 Score =  228 bits (582), Expect = 1e-60
 Identities = 106/147 (72%), Positives = 127/147 (86%)

Query: 1   MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK 60
           M H T E+K  + +LWGKVNV+  GGE LGRLLVVYPWTQRFF+SFG+LSS  A+MGNPK
Sbjct: 1   MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK 60

Query: 61  VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG 120
           VKAHGKKVL +  D + HLD+LKGTF+QLSELHCDKLHVDPENF+LLGNVLV VLA +FG
Sbjct: 61  VKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG 120

Query: 121 KEFTPQMQAAYQKVVAGVANALAHKYH 147
           KEFTP++QA++QK+V GVA+AL+ +YH
Sbjct: 121 KEFTPEVQASWQKMVTGVASALSSRYH 147


>gi|28302131 A-gamma globin [Homo sapiens]
          Length = 147

 Score =  225 bits (573), Expect = 1e-59
 Identities = 105/147 (71%), Positives = 125/147 (85%)

Query: 1   MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK 60
           M H T E+K  + +LWGKVNV+  GGE LGRLLVVYPWTQRFF+SFG+LSS  A+MGNPK
Sbjct: 1   MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK 60

Query: 61  VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG 120
           VKAHGKKVL +  D   HLD+LKGTF+QLSELHCDKLHVDPENF+LLGNVLV VLA +FG
Sbjct: 61  VKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG 120

Query: 121 KEFTPQMQAAYQKVVAGVANALAHKYH 147
           KEFTP++QA++QK+V  VA+AL+ +YH
Sbjct: 121 KEFTPEVQASWQKMVTAVASALSSRYH 147


>gi|4504347 alpha 1 globin [Homo sapiens]
          Length = 142

 Score =  113 bits (282), Expect = 7e-26
 Identities = 63/145 (43%), Positives = 87/145 (60%), Gaps = 8/145 (5%)

Query: 4   LTPEEKTAVNALWGKVNVDA--VGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPKV 61
           L+P +KT V A WGKV   A   G EAL R+ + +P T+ +F  F DLS      G+ +V
Sbjct: 3   LSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHF-DLSH-----GSAQV 56

Query: 62  KAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFGK 121
           K HGKKV  A ++ +AH+D++    S LS+LH  KL VDP NF+LL + L+  LA +   
Sbjct: 57  KGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPA 116

Query: 122 EFTPQMQAAYQKVVAGVANALAHKY 146
           EFTP + A+  K +A V+  L  KY
Sbjct: 117 EFTPAVHASLDKFLASVSTVLTSKY 141


>gi|4504345 alpha 2 globin [Homo sapiens]
          Length = 142

 Score =  113 bits (282), Expect = 7e-26
 Identities = 63/145 (43%), Positives = 87/145 (60%), Gaps = 8/145 (5%)

Query: 4   LTPEEKTAVNALWGKVNVDA--VGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPKV 61
           L+P +KT V A WGKV   A   G EAL R+ + +P T+ +F  F DLS      G+ +V
Sbjct: 3   LSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHF-DLSH-----GSAQV 56

Query: 62  KAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFGK 121
           K HGKKV  A ++ +AH+D++    S LS+LH  KL VDP NF+LL + L+  LA +   
Sbjct: 57  KGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPA 116

Query: 122 EFTPQMQAAYQKVVAGVANALAHKY 146
           EFTP + A+  K +A V+  L  KY
Sbjct: 117 EFTPAVHASLDKFLASVSTVLTSKY 141


>gi|4885397 hemoglobin, zeta [Homo sapiens]
          Length = 142

 Score =  101 bits (252), Expect = 2e-22
 Identities = 54/145 (37%), Positives = 85/145 (58%), Gaps = 8/145 (5%)

Query: 4   LTPEEKTAVNALWGKVNV--DAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPKV 61
           LT  E+T + ++W K++   D +G E L RL + +P T+ +F  F      D   G+ ++
Sbjct: 3   LTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF------DLHPGSAQL 56

Query: 62  KAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFGK 121
           +AHG KV+ A  D +  +D++ G  S+LSELH   L VDP NF+LL + L+  LA  F  
Sbjct: 57  RAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAARFPA 116

Query: 122 EFTPQMQAAYQKVVAGVANALAHKY 146
           +FT +  AA+ K ++ V++ L  KY
Sbjct: 117 DFTAEAHAAWDKFLSVVSSVLTEKY 141


>gi|4885395 theta 1 globin [Homo sapiens]
          Length = 142

 Score = 95.1 bits (235), Expect = 2e-20
 Identities = 57/145 (39%), Positives = 86/145 (59%), Gaps = 8/145 (5%)

Query: 4   LTPEEKTAVNALWGKV--NVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPKV 61
           L+ E++  V ALW K+  NV     EAL R  + +P T+ +F    DLS      G+ +V
Sbjct: 3   LSAEDRALVRALWKKLGSNVGVYTTEALERTFLAFPATKTYFSHL-DLSP-----GSSQV 56

Query: 62  KAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFGK 121
           +AHG+KV  A S  +  LD+L    S LS LH  +L VDP +F+LLG+ L+  LAR++  
Sbjct: 57  RAHGQKVADALSLAVERLDDLPHALSALSHLHACQLRVDPASFQLLGHCLLVTLARHYPG 116

Query: 122 EFTPQMQAAYQKVVAGVANALAHKY 146
           +F+P +QA+  K ++ V +AL  +Y
Sbjct: 117 DFSPALQASLDKFLSHVISALVSEY 141


>gi|51510893 hemoglobin mu chain [Homo sapiens]
          Length = 141

 Score = 84.7 bits (208), Expect = 2e-17
 Identities = 52/145 (35%), Positives = 75/145 (51%), Gaps = 8/145 (5%)

Query: 4   LTPEEKTAVNALWGKV--NVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPKV 61
           L+ +E+  +  +W  +  +    G E L RL  VYP T+ +F          A     ++
Sbjct: 2   LSAQERAQIAQVWDLIAGHEAQFGAELLLRLFTVYPSTKVYFPHLS------ACQDATQL 55

Query: 62  KAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFGK 121
            +HG+++L A    + H+DNL+   S L++LH   L VDP NF LL      VLA +   
Sbjct: 56  LSHGQRMLAAVGAAVQHVDNLRAALSPLADLHALVLRVDPANFPLLIQCFHVVLASHLQD 115

Query: 122 EFTPQMQAAYQKVVAGVANALAHKY 146
           EFT QMQAA+ K + GVA  L  KY
Sbjct: 116 EFTVQMQAAWDKFLTGVAVVLTEKY 140


>gi|19549331 cytoglobin [Homo sapiens]
          Length = 190

 Score = 69.3 bits (168), Expect = 1e-12
 Identities = 38/136 (27%), Positives = 73/136 (53%), Gaps = 5/136 (3%)

Query: 4   LTPEEKTAVNALWGKV--NVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPKV 61
           L+  E+ AV A+W ++  N + VG   L R  V +P  +++F  F  +  P  +  +P++
Sbjct: 19  LSEAERKAVQAMWARLYANCEDVGVAILVRFFVNFPSAKQYFSQFKHMEDPLEMERSPQL 78

Query: 62  KAHGKKVLGAFSDGLAHL---DNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARN 118
           + H  +V+GA +  + +L   D +    + + + H  K  V+P  F++L  V++ V+A  
Sbjct: 79  RKHACRVMGALNTVVENLHDPDKVSSVLALVGKAHALKHKVEPVYFKILSGVILEVVAEE 138

Query: 119 FGKEFTPQMQAAYQKV 134
           F  +F P+ Q A+ K+
Sbjct: 139 FASDFPPETQRAWAKL 154


>gi|10864065 neuroglobin [Homo sapiens]
          Length = 151

 Score = 36.6 bits (83), Expect = 0.008
 Identities = 23/96 (23%), Positives = 47/96 (48%), Gaps = 2/96 (2%)

Query: 50  SSPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFSQLSEL--HCDKLHVDPENFRLL 107
           SSP+  + +P+   H +KV+      + ++++L      L+ L      + V   +F  +
Sbjct: 50  SSPEDCLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLASLGRKHRAVGVKLSSFSTV 109

Query: 108 GNVLVCVLARNFGKEFTPQMQAAYQKVVAGVANALA 143
           G  L+ +L +  G  FTP  +AA+ ++   V  A++
Sbjct: 110 GESLLYMLEKCLGPAFTPATRAAWSQLYGAVVQAMS 145


>gi|46397369 leucine rich repeat containing 20 isoform 1 [Homo
           sapiens]
          Length = 184

 Score = 27.7 bits (60), Expect = 3.6
 Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 2/47 (4%)

Query: 85  TFSQLSELHCDK--LHVDPENFRLLGNVLVCVLARNFGKEFTPQMQA 129
           TFSQL ELH +   LH  P     L ++    L+RN  ++F  Q+ A
Sbjct: 72  TFSQLRELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTA 118


>gi|167466264 leucine rich repeat containing 18 [Homo sapiens]
          Length = 261

 Score = 26.6 bits (57), Expect = 8.0
 Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 5/48 (10%)

Query: 67  KVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCV 114
           K + A + GL HLD++  T   L ELH   LH +     LL N+ V +
Sbjct: 121 KNIRAVNLGLNHLDSVPTTLGALKELHEVGLHDN-----LLNNIPVSI 163


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,489,696
Number of Sequences: 37866
Number of extensions: 214654
Number of successful extensions: 399
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 384
Number of HSP's gapped (non-prelim): 14
length of query: 147
length of database: 18,247,518
effective HSP length: 93
effective length of query: 54
effective length of database: 14,725,980
effective search space: 795202920
effective search space used: 795202920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.