Search of human proteins with 4504349

Search of human proteins with 4504349

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504349 beta globin [Homo sapiens]
         (147 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504349 beta globin [Homo sapiens]                                 305   1e-83
gi|4504351 delta globin [Homo sapiens]                                284   2e-77
gi|4885393 epsilon globin [Homo sapiens]                              238   1e-63
gi|6715607 G-gamma globin [Homo sapiens]                              233   6e-62
gi|28302131 A-gamma globin [Homo sapiens]                             229   6e-61
gi|4504347 alpha 1 globin [Homo sapiens]                              114   3e-26
gi|4504345 alpha 2 globin [Homo sapiens]                              114   3e-26
gi|4885397 hemoglobin, zeta [Homo sapiens]                             98   3e-21
gi|4885395 theta 1 globin [Homo sapiens]                               94   4e-20
gi|51510893 hemoglobin mu chain [Homo sapiens]                         85   2e-17
gi|19549331 cytoglobin [Homo sapiens]                                  71   3e-13
gi|163644316 hypothetical protein LOC23255 [Homo sapiens]              29   1.2  
gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapi...    28   2.8  
gi|167466264 leucine rich repeat containing 18 [Homo sapiens]          27   6.1  
gi|109637791 transcription factor-like nuclear regulator [Homo s...    27   8.0  

>gi|4504349 beta globin [Homo sapiens]
          Length = 147

 Score =  305 bits (780), Expect = 1e-83
 Identities = 147/147 (100%), Positives = 147/147 (100%)

Query: 1   MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK 60
           MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK
Sbjct: 1   MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK 60

Query: 61  VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFG 120
           VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFG
Sbjct: 61  VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFG 120

Query: 121 KEFTPPVQAAYQKVVAGVANALAHKYH 147
           KEFTPPVQAAYQKVVAGVANALAHKYH
Sbjct: 121 KEFTPPVQAAYQKVVAGVANALAHKYH 147


>gi|4504351 delta globin [Homo sapiens]
          Length = 147

 Score =  284 bits (727), Expect = 2e-77
 Identities = 137/147 (93%), Positives = 142/147 (96%)

Query: 1   MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK 60
           MVHLTPEEK+AV ALWGKVNVD VGGEALGRLLVVYPWTQRFFESFGDLS+PDAVMGNPK
Sbjct: 1   MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK 60

Query: 61  VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFG 120
           VKAHGKKVLGAFSDGLAHLDNLKGTF+ LSELHCDKLHVDPENFRLLGNVLVCVLA +FG
Sbjct: 61  VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG 120

Query: 121 KEFTPPVQAAYQKVVAGVANALAHKYH 147
           KEFTP +QAAYQKVVAGVANALAHKYH
Sbjct: 121 KEFTPQMQAAYQKVVAGVANALAHKYH 147


>gi|4885393 epsilon globin [Homo sapiens]
          Length = 147

 Score =  238 bits (607), Expect = 1e-63
 Identities = 111/147 (75%), Positives = 130/147 (88%)

Query: 1   MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK 60
           MVH T EEK+AVT+LW K+NV+E GGEALGRLLVVYPWTQRFF+SFG+LS+P A++GNPK
Sbjct: 1   MVHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGNPK 60

Query: 61  VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFG 120
           VKAHGKKVL +F D + ++DNLK  FA LSELHCDKLHVDPENF+LLGNV+V +LA HFG
Sbjct: 61  VKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFG 120

Query: 121 KEFTPPVQAAYQKVVAGVANALAHKYH 147
           KEFTP VQAA+QK+V+ VA ALAHKYH
Sbjct: 121 KEFTPEVQAAWQKLVSAVAIALAHKYH 147


>gi|6715607 G-gamma globin [Homo sapiens]
          Length = 147

 Score =  233 bits (593), Expect = 6e-62
 Identities = 108/147 (73%), Positives = 128/147 (87%)

Query: 1   MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK 60
           M H T E+K+ +T+LWGKVNV++ GGE LGRLLVVYPWTQRFF+SFG+LS+  A+MGNPK
Sbjct: 1   MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK 60

Query: 61  VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFG 120
           VKAHGKKVL +  D + HLD+LKGTFA LSELHCDKLHVDPENF+LLGNVLV VLA HFG
Sbjct: 61  VKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG 120

Query: 121 KEFTPPVQAAYQKVVAGVANALAHKYH 147
           KEFTP VQA++QK+V GVA+AL+ +YH
Sbjct: 121 KEFTPEVQASWQKMVTGVASALSSRYH 147


>gi|28302131 A-gamma globin [Homo sapiens]
          Length = 147

 Score =  229 bits (584), Expect = 6e-61
 Identities = 107/147 (72%), Positives = 126/147 (85%)

Query: 1   MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK 60
           M H T E+K+ +T+LWGKVNV++ GGE LGRLLVVYPWTQRFF+SFG+LS+  A+MGNPK
Sbjct: 1   MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK 60

Query: 61  VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFG 120
           VKAHGKKVL +  D   HLD+LKGTFA LSELHCDKLHVDPENF+LLGNVLV VLA HFG
Sbjct: 61  VKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG 120

Query: 121 KEFTPPVQAAYQKVVAGVANALAHKYH 147
           KEFTP VQA++QK+V  VA+AL+ +YH
Sbjct: 121 KEFTPEVQASWQKMVTAVASALSSRYH 147


>gi|4504347 alpha 1 globin [Homo sapiens]
          Length = 142

 Score =  114 bits (285), Expect = 3e-26
 Identities = 61/145 (42%), Positives = 86/145 (59%), Gaps = 8/145 (5%)

Query: 4   LTPEEKSAVTALWGKV--NVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKV 61
           L+P +K+ V A WGKV  +  E G EAL R+ + +P T+ +F  F      D   G+ +V
Sbjct: 3   LSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHF------DLSHGSAQV 56

Query: 62  KAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGK 121
           K HGKKV  A ++ +AH+D++    + LS+LH  KL VDP NF+LL + L+  LA H   
Sbjct: 57  KGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPA 116

Query: 122 EFTPPVQAAYQKVVAGVANALAHKY 146
           EFTP V A+  K +A V+  L  KY
Sbjct: 117 EFTPAVHASLDKFLASVSTVLTSKY 141


>gi|4504345 alpha 2 globin [Homo sapiens]
          Length = 142

 Score =  114 bits (285), Expect = 3e-26
 Identities = 61/145 (42%), Positives = 86/145 (59%), Gaps = 8/145 (5%)

Query: 4   LTPEEKSAVTALWGKV--NVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKV 61
           L+P +K+ V A WGKV  +  E G EAL R+ + +P T+ +F  F      D   G+ +V
Sbjct: 3   LSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHF------DLSHGSAQV 56

Query: 62  KAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGK 121
           K HGKKV  A ++ +AH+D++    + LS+LH  KL VDP NF+LL + L+  LA H   
Sbjct: 57  KGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPA 116

Query: 122 EFTPPVQAAYQKVVAGVANALAHKY 146
           EFTP V A+  K +A V+  L  KY
Sbjct: 117 EFTPAVHASLDKFLASVSTVLTSKY 141


>gi|4885397 hemoglobin, zeta [Homo sapiens]
          Length = 142

 Score = 97.8 bits (242), Expect = 3e-21
 Identities = 52/145 (35%), Positives = 83/145 (57%), Gaps = 8/145 (5%)

Query: 4   LTPEEKSAVTALWGKVNV--DEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKV 61
           LT  E++ + ++W K++   D +G E L RL + +P T+ +F  F      D   G+ ++
Sbjct: 3   LTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF------DLHPGSAQL 56

Query: 62  KAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGK 121
           +AHG KV+ A  D +  +D++ G  + LSELH   L VDP NF+LL + L+  LA  F  
Sbjct: 57  RAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAARFPA 116

Query: 122 EFTPPVQAAYQKVVAGVANALAHKY 146
           +FT    AA+ K ++ V++ L  KY
Sbjct: 117 DFTAEAHAAWDKFLSVVSSVLTEKY 141


>gi|4885395 theta 1 globin [Homo sapiens]
          Length = 142

 Score = 94.0 bits (232), Expect = 4e-20
 Identities = 56/145 (38%), Positives = 86/145 (59%), Gaps = 8/145 (5%)

Query: 4   LTPEEKSAVTALWGKV--NVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKV 61
           L+ E+++ V ALW K+  NV     EAL R  + +P T+ +F    DLS      G+ +V
Sbjct: 3   LSAEDRALVRALWKKLGSNVGVYTTEALERTFLAFPATKTYFSHL-DLSP-----GSSQV 56

Query: 62  KAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGK 121
           +AHG+KV  A S  +  LD+L    + LS LH  +L VDP +F+LLG+ L+  LA H+  
Sbjct: 57  RAHGQKVADALSLAVERLDDLPHALSALSHLHACQLRVDPASFQLLGHCLLVTLARHYPG 116

Query: 122 EFTPPVQAAYQKVVAGVANALAHKY 146
           +F+P +QA+  K ++ V +AL  +Y
Sbjct: 117 DFSPALQASLDKFLSHVISALVSEY 141


>gi|51510893 hemoglobin mu chain [Homo sapiens]
          Length = 141

 Score = 85.1 bits (209), Expect = 2e-17
 Identities = 51/145 (35%), Positives = 75/145 (51%), Gaps = 8/145 (5%)

Query: 4   LTPEEKSAVTALWGKVNVDEV--GGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKV 61
           L+ +E++ +  +W  +   E   G E L RL  VYP T+ +F          A     ++
Sbjct: 2   LSAQERAQIAQVWDLIAGHEAQFGAELLLRLFTVYPSTKVYFPHLS------ACQDATQL 55

Query: 62  KAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGK 121
            +HG+++L A    + H+DNL+   + L++LH   L VDP NF LL      VLA H   
Sbjct: 56  LSHGQRMLAAVGAAVQHVDNLRAALSPLADLHALVLRVDPANFPLLIQCFHVVLASHLQD 115

Query: 122 EFTPPVQAAYQKVVAGVANALAHKY 146
           EFT  +QAA+ K + GVA  L  KY
Sbjct: 116 EFTVQMQAAWDKFLTGVAVVLTEKY 140


>gi|19549331 cytoglobin [Homo sapiens]
          Length = 190

 Score = 71.2 bits (173), Expect = 3e-13
 Identities = 39/136 (28%), Positives = 73/136 (53%), Gaps = 5/136 (3%)

Query: 4   LTPEEKSAVTALWGKV--NVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKV 61
           L+  E+ AV A+W ++  N ++VG   L R  V +P  +++F  F  +  P  +  +P++
Sbjct: 19  LSEAERKAVQAMWARLYANCEDVGVAILVRFFVNFPSAKQYFSQFKHMEDPLEMERSPQL 78

Query: 62  KAHGKKVLGAFSDGLAHL---DNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHH 118
           + H  +V+GA +  + +L   D +    A + + H  K  V+P  F++L  V++ V+A  
Sbjct: 79  RKHACRVMGALNTVVENLHDPDKVSSVLALVGKAHALKHKVEPVYFKILSGVILEVVAEE 138

Query: 119 FGKEFTPPVQAAYQKV 134
           F  +F P  Q A+ K+
Sbjct: 139 FASDFPPETQRAWAKL 154


>gi|163644316 hypothetical protein LOC23255 [Homo sapiens]
          Length = 1586

 Score = 29.3 bits (64), Expect = 1.2
 Identities = 17/47 (36%), Positives = 21/47 (44%)

Query: 80  DNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPP 126
           + LK     +SEL    L +  EN  LL N+  C LA H G     P
Sbjct: 336 EELKSARLQISELSGKVLKLQHENHALLSNIQRCDLAAHLGLRAPSP 382


>gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo
           sapiens]
          Length = 464

 Score = 28.1 bits (61), Expect = 2.8
 Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 17/90 (18%)

Query: 38  WTQRFFESF----GDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELH 93
           W Q  ++ F    GDL+    ++ N K+K      L  + D   +  NLK  +       
Sbjct: 89  WLQSAYKEFDRKDGDLTMWPRLVSNSKLKRSSHLSLPKYWD-YRYKKNLKALYV------ 141

Query: 94  CDKLHVDPENF-RLLGNVLVCVLAHHFGKE 122
                V P +F ++L N+L  +++H FGK+
Sbjct: 142 -----VHPTSFIKVLWNILKPLISHKFGKK 166


>gi|167466264 leucine rich repeat containing 18 [Homo sapiens]
          Length = 261

 Score = 26.9 bits (58), Expect = 6.1
 Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 5/48 (10%)

Query: 67  KVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCV 114
           K + A + GL HLD++  T   L ELH   LH +     LL N+ V +
Sbjct: 121 KNIRAVNLGLNHLDSVPTTLGALKELHEVGLHDN-----LLNNIPVSI 163


>gi|109637791 transcription factor-like nuclear regulator [Homo
            sapiens]
          Length = 2624

 Score = 26.6 bits (57), Expect = 8.0
 Identities = 11/36 (30%), Positives = 18/36 (50%)

Query: 79   LDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCV 114
            ++ + G  A + E+  D      ENFR  G+  +CV
Sbjct: 1265 MEKVSGKMAVVEEMEADLKETGKENFRERGSEEICV 1300


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,791,224
Number of Sequences: 37866
Number of extensions: 227147
Number of successful extensions: 445
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 429
Number of HSP's gapped (non-prelim): 15
length of query: 147
length of database: 18,247,518
effective HSP length: 93
effective length of query: 54
effective length of database: 14,725,980
effective search space: 795202920
effective search space used: 795202920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.