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Search of human proteins with 4503421
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
(384 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 773 0.0
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 378 e-105
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens] 367 e-101
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens] 176 2e-44
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 167 1e-41
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 164 9e-41
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 163 2e-40
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 161 8e-40
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 157 1e-38
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens] 156 3e-38
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 147 2e-35
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 126 3e-29
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi... 126 3e-29
gi|42764687 dual specificity phosphatase 6 isoform b [Homo sapiens] 126 4e-29
gi|239047414 slingshot 1 isoform 1 [Homo sapiens] 103 2e-22
gi|239047498 slingshot 1 isoform 3 [Homo sapiens] 103 2e-22
gi|239047441 slingshot 1 isoform 2 [Homo sapiens] 103 2e-22
gi|37674210 slingshot 2 [Homo sapiens] 103 2e-22
gi|9910432 dual specificity phosphatase 22 [Homo sapiens] 97 2e-20
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 94 2e-19
gi|5902002 dual specificity phosphatase 14 [Homo sapiens] 89 7e-18
gi|239582767 slingshot homolog 3 [Homo sapiens] 88 1e-17
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ... 87 2e-17
gi|194733759 serine/threonine/tyrosine interacting protein [Homo... 87 2e-17
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ... 87 2e-17
gi|4758208 dual specificity phosphatase 3 [Homo sapiens] 87 3e-17
gi|13128968 dual specificity phosphatase 26 [Homo sapiens] 82 6e-16
gi|56117818 muscle-restricted dual specificity phosphatase isofo... 78 2e-14
gi|51491914 dual specificity phosphatase and pro isomerase domai... 77 3e-14
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi... 76 4e-14
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 773 bits (1996), Expect = 0.0
Identities = 384/384 (100%), Positives = 384/384 (100%)
Query: 1 MEGLGRSCLWLRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLS 60
MEGLGRSCLWLRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLS
Sbjct: 1 MEGLGRSCLWLRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLS 60
Query: 61 VRALLPGPPLQPPPPAPVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLA 120
VRALLPGPPLQPPPPAPVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLA
Sbjct: 61 VRALLPGPPLQPPPPAPVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLA 120
Query: 121 YYLQGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADR 180
YYLQGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADR
Sbjct: 121 YYLQGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADR 180
Query: 181 DSMSCGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNL 240
DSMSCGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNL
Sbjct: 181 DSMSCGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNL 240
Query: 241 PNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTV 300
PNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTV
Sbjct: 241 PNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTV 300
Query: 301 TVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSGGQA 360
TVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSGGQA
Sbjct: 301 TVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSGGQA 360
Query: 361 SAASNPPSFFTTPTSDGAFELAPT 384
SAASNPPSFFTTPTSDGAFELAPT
Sbjct: 361 SAASNPPSFFTTPTSDGAFELAPT 384
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 378 bits (970), Expect = e-105
Identities = 213/382 (55%), Positives = 262/382 (68%), Gaps = 29/382 (7%)
Query: 6 RSCLWLRRELSPPR-PRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLSVRAL 64
+S WL+ EL LLLLDCR EL+ES+ I A+++A+P L+LRRLR+G+L +R++
Sbjct: 55 KSAEWLQEELEARGGASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSI 114
Query: 65 LPGPPLQPP-----PPAPVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYL 119
+P + A VLLYD+ AE + E SVLG LLQKLR++G
Sbjct: 115 IPNHADKERFATRCKAATVLLYDEA-------TAEWQPEPGAPASVLGLLLQKLRDDGCQ 167
Query: 120 AYYLQGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEAD 179
AYYLQGGF++FQ E CET++ + S +P P V+GLG L + SDCSD ES D
Sbjct: 168 AYYLQGGFNKFQTEYSEHCETNVDSSSSPSSSP---PTSVLGLGGLRISSDCSDGES--D 222
Query: 180 RDSMSCGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPN 239
R+ S +S+G+ P + +FPVQILP LYLG A+DS NL+ L K GI+YILNVTPN
Sbjct: 223 RELPSSATESDGSPVP--SSQPAFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPN 280
Query: 240 LPNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVT 299
LPN FE G+F YKQIPISDHWSQNLS+FFPEAI FIDEA S+ CGVLVHCLAG+SRSVT
Sbjct: 281 LPNAFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVT 340
Query: 300 VTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSGGQ 359
VTVAYLMQK++LSLNDAYD VKRKKSNISPNFNFMGQLLDFER+L L S
Sbjct: 341 VTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFERTLGL---------SSPC 391
Query: 360 ASAASNPPSFFTTPTSDGAFEL 381
+ AS+ +F+TPT+ F L
Sbjct: 392 DNHASSEQLYFSTPTNHNLFPL 413
>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
Length = 381
Score = 367 bits (941), Expect = e-101
Identities = 207/384 (53%), Positives = 259/384 (67%), Gaps = 30/384 (7%)
Query: 4 LGRSCLWLRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLSVRA 63
+ ++ WL +L RLLL+DCR +ELYES+ I A++VA+P ++LRRL++G+L VRA
Sbjct: 16 ISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRA 75
Query: 64 LLPGPP-----LQPPPPAPVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGY 118
L + V+LYD+ E ESVLG LL+KL++EG
Sbjct: 76 LFTRGEDRDRFTRRCGTDTVVLYDESSSDWN--------ENTGGESVLGLLLKKLKDEGC 127
Query: 119 LAYYLQGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCS-DAESE 177
A+YL+GGFS+FQAE CET+L G SS P+P V+GLG L + SD S D ES+
Sbjct: 128 RAFYLEGGFSKFQAEFSLHCETNLDGSCSSSSPPLP----VLGLGGLRISSDSSSDIESD 183
Query: 178 ADRDSMSCGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVT 237
DRD S DS+G+ P + SFPV+ILP LYLG A+DS NL+ L + GI+YILNVT
Sbjct: 184 LDRDPNSA-TDSDGS--PLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT 240
Query: 238 PNLPNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRS 297
PNLPN FE G+F YKQIPISDHWSQNLS+FFPEAI FIDEA +NCGVLVHCLAG+SRS
Sbjct: 241 PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS 300
Query: 298 VTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSG 357
VTVTVAYLMQKL+LS+NDAYD+VK KKSNISPNFNFMGQLLDFER+L L S
Sbjct: 301 VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGL---------SS 351
Query: 358 GQASAASNPPSFFTTPTSDGAFEL 381
+ +FTTP++ +++
Sbjct: 352 PCDNRVPAQQLYFTTPSNQNVYQV 375
>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
Length = 394
Score = 176 bits (447), Expect = 2e-44
Identities = 130/372 (34%), Positives = 186/372 (50%), Gaps = 54/372 (14%)
Query: 17 PPRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLSVRALLPGPP-----LQ 71
P + LLLDCR + + I G+++V ++ RR + GS+S+ +LP L+
Sbjct: 40 PSGGKCLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRAK-GSVSLEQILPAEEEVRARLR 98
Query: 72 PPPPAPVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLA--YYLQGGFSR 129
+ V++YD+ R AE +S + ++Q LR L+GG+ R
Sbjct: 99 SGLYSAVIVYDERSPR---------AESLREDSTVSLVVQALRRNAERTDICLLKGGYER 149
Query: 130 FQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADRDSMSCG--L 187
F +E P C + A +A +P PVP L LG CS SCG L
Sbjct: 150 FSSEYPEFCSKTKA------LAAIPPPVPPSATEPLDLG--CS-----------SCGTPL 190
Query: 188 DSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKN 247
+G PV+ILP LYLGSA +A + L LGI +LNV+ + PN FE
Sbjct: 191 HDQGG-----------PVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFE-- 237
Query: 248 GDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQ 307
G + YK IP+ D+ ++S +F EAIE+ID VLVHC AG+SRS T+ +AYLM
Sbjct: 238 GHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMM 297
Query: 308 KLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSGGQASAASNPP 367
K + L +A++ VK+++S ISPNF+FMGQLL FE + ++ G P
Sbjct: 298 KKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKTP 357
Query: 368 SFFTTPTSDGAF 379
+ TPTS F
Sbjct: 358 A---TPTSQFVF 366
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 167 bits (424), Expect = 1e-41
Identities = 125/371 (33%), Positives = 189/371 (50%), Gaps = 45/371 (12%)
Query: 11 LRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLSVRALLPGPPL 70
LR L + LLLDCRS + + I G+++V + ++RR +G++ + ++P L
Sbjct: 13 LRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRF-STIVRRRAKGAMGLEHIVPNAEL 71
Query: 71 QPPPPA----PVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLAYYLQGG 126
+ A V+L D+ R + + G L ++ R ++L+GG
Sbjct: 72 RGRLLAGAYHAVVLLDE-----RSAALDGAKRDGTLALAAGALCREARAAQ--VFFLKGG 124
Query: 127 FSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADRDSMSCG 186
+ F A CP LC S P +GL SL L + D+ +E+ S S
Sbjct: 125 YEAFSASCPELC----------SKQSTP-----MGL-SLPLSTSVPDS-AESGCSSCSTP 167
Query: 187 LDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEK 246
L +G PV+ILP LYLGSA ++ + L LGI ++NV+ N PN FE
Sbjct: 168 LYDQGG-----------PVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFE- 215
Query: 247 NGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLM 306
G + YK IP+ D+ ++S +F EAI+FID + V VHC AG+SRS T+ +AYLM
Sbjct: 216 -GHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLM 274
Query: 307 QKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSGGQA--SAAS 364
+ + L++A++ VK+++S ISPNF+FMGQLL FE + L S E GS A +
Sbjct: 275 RTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQV-LAPHCSAEAGSPAMAVLDRGT 333
Query: 365 NPPSFFTTPTS 375
+ + F P S
Sbjct: 334 STTTVFNFPVS 344
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 164 bits (416), Expect = 9e-41
Identities = 126/341 (36%), Positives = 165/341 (48%), Gaps = 50/341 (14%)
Query: 8 CLWLRRELSPPRP--RLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLSVRA-L 64
C L L PR R LLLDCR + + A V ALL RR R +V A L
Sbjct: 11 CAALGTLLRDPREAERTLLLDCRPFLAFCRRHVRAARPVPWNALLRRRARGPPAAVLACL 70
Query: 65 LPGPPLQPP----PPAPVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLA 120
LP L+ A ++ D+G AE + A +L LL + R
Sbjct: 71 LPDRALRTRLVRGELARAVVLDEGSA----SVAELRPDS-PAHVLLAALLHETRAGPTAV 125
Query: 121 YYLQGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADR 180
Y+L+GGF FQ CP LC S AP P P + +
Sbjct: 126 YFLRGGFDGFQGCCPDLC----------SEAPAPALPPT--------------GDKTSRS 161
Query: 181 DSMSCGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNL 240
DS + D G PV+ILP L+LGS S++L+ L GI +LNV+ +
Sbjct: 162 DSRAPVYDQGG------------PVEILPYLFLGSCSHSSDLQGLQACGITAVLNVSASC 209
Query: 241 PNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTV 300
PN FE G F YK IP+ D+ +S +F EAI FID + VLVHC AG+SRS T+
Sbjct: 210 PNHFE--GLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVHCQAGISRSATI 267
Query: 301 TVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFE 341
+AYLMQ + L++A+D VK+++ ISPNF+FMGQLL FE
Sbjct: 268 CLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFE 308
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 163 bits (413), Expect = 2e-40
Identities = 113/352 (32%), Positives = 176/352 (50%), Gaps = 66/352 (18%)
Query: 23 LLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLSVRALLPGPP---LQPPPPAPVL 79
L++D RS Y S + ++++ L+ RRL++G +++ L+ ++ P V+
Sbjct: 28 LVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQQGKVTIAELIQPAARSQVEATEPQDVV 87
Query: 80 LYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLAYYLQGGFSRFQAECPHLCE 139
+YDQ + +A A+S L LL KL L GGF+ F + P LCE
Sbjct: 88 VYDQ---------STRDASVLAADSFLSILLSKLDGCFDSVAILTGGFATFSSCFPGLCE 138
Query: 140 TSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADRDSMSCGLDSEGATPPPVGL 199
A S++ PVP VGL
Sbjct: 139 GKPAALLPMSLSQPCLPVPSVGL------------------------------------- 161
Query: 200 RASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDF----HYKQI 255
+ILP+LYLGS +D N + + + GI Y+LN + + P DF + ++
Sbjct: 162 -----TRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPK-----PDFICESRFMRV 211
Query: 256 PISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLND 315
PI+D++ + L + ++IEFID+A +C V+VHCLAG+SRS T+ +AY+M+ + +S +D
Sbjct: 212 PINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDD 271
Query: 316 AYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSGGQASAASNPP 367
AY VK ++ +ISPNFNF+GQLL++ERSL+L + QG G S PP
Sbjct: 272 AYRFVKDRRPSISPNFNFLGQLLEYERSLKL---LAALQGDPGTPSGTPEPP 320
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 161 bits (408), Expect = 8e-40
Identities = 108/335 (32%), Positives = 169/335 (50%), Gaps = 58/335 (17%)
Query: 23 LLLDCRSRELYESARIGGALSV-ALPALLLRRLRRGSLSVRALLP----GPPLQPPPPAP 77
+++DCR Y + I GA+ + + RRL++G ++V L+ +
Sbjct: 173 VIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFKRIFSKE 232
Query: 78 VLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLAYYLQGGFSRFQAECPHL 137
+++YD+ E L +L+ L+ EG L+GG S F+ +L
Sbjct: 233 IIVYDENTN---------EPSRVMPSQPLHIVLESLKREGKEPLVLKGGLSSFKQNHENL 283
Query: 138 CETSL--------AGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADRDSMSCGLDS 189
C+ SL G A ++ + +P P+P D +AE
Sbjct: 284 CDNSLQLQECREVGGGASAASSLLPQPIPTT--------PDIENAE-------------- 321
Query: 190 EGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGD 249
TP ILP L+LG+ +D+ +L+++ +L I Y++NVT +LP + + G
Sbjct: 322 --LTP------------ILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGL 367
Query: 250 FHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKL 309
F+YK++P +D QNL ++F EA EFI+EA G+L+HC AGVSRS T+ +AYLM+
Sbjct: 368 FNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHT 427
Query: 310 HLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSL 344
+++ DAY VK K+ ISPN NFMGQLL+FE L
Sbjct: 428 RMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 462
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 157 bits (398), Expect = 1e-38
Identities = 118/362 (32%), Positives = 181/362 (50%), Gaps = 47/362 (12%)
Query: 11 LRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLSVRALLPGPPL 70
LR+E + R ++LDCR + ++ + G+L+V L +++LRR R G++S R +LP
Sbjct: 15 LRKEAAA---RCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAVSARYVLPDEAA 71
Query: 71 QPPPPAPVLLYDQGGGRRRRGEAEAEAEEWE-------AESVLGTLLQKLREEGYLAYYL 123
+ LL + GGG + + W+ A VL +LL L G Y+L
Sbjct: 72 RAR-----LLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACL-PAGPRVYFL 125
Query: 124 QGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADRDSM 183
+GG+ F +E P C + P+ S + E++R +
Sbjct: 126 KGGYETFYSEYPECCV---------DVKPI------------------SQEKIESERALI 158
Query: 184 S-CGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPN 242
S CG + P + PV+ILP LYLGSA ++ E LA L I +LNV+
Sbjct: 159 SQCGKPVVNVSYRPAYDQGG-PVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSE 217
Query: 243 FFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTV 302
+ HYK IP+ D + ++S F EAI+FID + VLVHC AG+SRS T+ +
Sbjct: 218 ACATH--LHYKWIPVEDSHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICM 275
Query: 303 AYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSGGQASA 362
AYLM+ L +A+D +K+++S +SPNF FMGQLL +E + + Q G+A+
Sbjct: 276 AYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAG 335
Query: 363 AS 364
+S
Sbjct: 336 SS 337
>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
Length = 303
Score = 156 bits (394), Expect = 3e-38
Identities = 102/258 (39%), Positives = 136/258 (52%), Gaps = 37/258 (14%)
Query: 124 QGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADRDSM 183
QGG+ RF +E P C + A +A +P PVP L LG CS
Sbjct: 53 QGGYERFSSEYPEFCSKTKA------LAAIPPPVPPSATEPLDLG--CS----------- 93
Query: 184 SCG--LDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLP 241
SCG L +G PV+ILP LYLGSA +A + L LGI +LNV+ + P
Sbjct: 94 SCGTPLHDQGG-----------PVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCP 142
Query: 242 NFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVT 301
N FE G + YK IP+ D+ ++S +F EAIE+ID VLVHC AG+SRS T+
Sbjct: 143 NHFE--GHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATIC 200
Query: 302 VAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSGGQAS 361
+AYLM K + L +A++ VK+++S ISPNF+FMGQLL FE + ++ G
Sbjct: 201 LAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLR 260
Query: 362 AASNPPSFFTTPTSDGAF 379
P+ TPTS F
Sbjct: 261 ERGKTPA---TPTSQFVF 275
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 147 bits (370), Expect = 2e-35
Identities = 97/330 (29%), Positives = 165/330 (50%), Gaps = 60/330 (18%)
Query: 21 RLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLSVRALLPGPPLQPPP---PAP 77
++LL+D R Y ++ I A+++ L+ RRL++ + + L+
Sbjct: 25 KVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHSAKHKVDIDCSQK 84
Query: 78 VLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLAYYLQGGFSRFQAECPHL 137
V++YDQ + + ++ L LL KL + + L GGF+ F P L
Sbjct: 85 VVVYDQ---------SSQDVASLSSDCFLTVLLGKLEKSFNSVHLLAGGFAEFSRCFPGL 135
Query: 138 CETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADRDSMSCGLDSEGATPPPV 197
CE S++ P C+ C + +
Sbjct: 136 CEGK------STLVPT------------CISQPCLPVAN--------------------I 157
Query: 198 GLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLP--NFFEKNGDFHYKQI 255
G P +ILPNLYLG RD N E + + GI Y+LN + P +F ++ H+ ++
Sbjct: 158 G-----PTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPES---HFLRV 209
Query: 256 PISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLND 315
P++D + + + + ++++FI++A + N VLVHCLAG+SRS T+ +AY+M+++ +SL++
Sbjct: 210 PVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDE 269
Query: 316 AYDLVKRKKSNISPNFNFMGQLLDFERSLR 345
AY VK K+ ISPNFNF+GQLLD+E+ ++
Sbjct: 270 AYRFVKEKRPTISPNFNFLGQLLDYEKKIK 299
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 126 bits (317), Expect = 3e-29
Identities = 60/120 (50%), Positives = 84/120 (70%)
Query: 225 LAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNC 284
+ +L I Y++NVT +LP + + G F+YK++P +D QNL ++F EA EFI+EA
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60
Query: 285 GVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSL 344
G+L+HC AGVSRS T+ +AYLM+ +++ DAY VK K+ ISPN NFMGQLL+FE L
Sbjct: 61 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120
>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 126 bits (317), Expect = 3e-29
Identities = 60/120 (50%), Positives = 84/120 (70%)
Query: 225 LAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNC 284
+ +L I Y++NVT +LP + + G F+YK++P +D QNL ++F EA EFI+EA
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60
Query: 285 GVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSL 344
G+L+HC AGVSRS T+ +AYLM+ +++ DAY VK K+ ISPN NFMGQLL+FE L
Sbjct: 61 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120
>gi|42764687 dual specificity phosphatase 6 isoform b [Homo sapiens]
Length = 235
Score = 126 bits (316), Expect = 4e-29
Identities = 65/105 (61%), Positives = 78/105 (74%), Gaps = 9/105 (8%)
Query: 277 DEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQ 336
DEA +NCGVLVHCLAG+SRSVTVTVAYLMQKL+LS+NDAYD+VK KKSNISPNFNFMGQ
Sbjct: 134 DEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQ 193
Query: 337 LLDFERSLRLEERHSQEQGSGGQASAASNPPSFFTTPTSDGAFEL 381
LLDFER+L L S + +FTTP++ +++
Sbjct: 194 LLDFERTLGL---------SSPCDNRVPAQQLYFTTPSNQNVYQV 229
Score = 81.6 bits (200), Expect = 1e-15
Identities = 49/126 (38%), Positives = 72/126 (57%), Gaps = 13/126 (10%)
Query: 4 LGRSCLWLRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLSVRA 63
+ ++ WL +L RLLL+DCR +ELYES+ I A++VA+P ++LRRL++G+L VRA
Sbjct: 16 ISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRA 75
Query: 64 LLPGPP-----LQPPPPAPVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGY 118
L + V+LYD+ E ESVLG LL+KL++EG
Sbjct: 76 LFTRGEDRDRFTRRCGTDTVVLYDESSSDWN--------ENTGGESVLGLLLKKLKDEGC 127
Query: 119 LAYYLQ 124
A+YL+
Sbjct: 128 RAFYLE 133
>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
Length = 1049
Score = 103 bits (258), Expect = 2e-22
Identities = 69/183 (37%), Positives = 97/183 (53%), Gaps = 8/183 (4%)
Query: 204 PVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQ 263
P I +LYLGS +++NLE L G+ YILNVT + NFF G F Y I + D +
Sbjct: 309 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFP--GLFAYHNIRVYDEETT 366
Query: 264 NLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRK 323
+L + EA FI++A + LVHC GVSRS + +AY M++ L AY+ VK+K
Sbjct: 367 DLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQK 426
Query: 324 KSNISPNFNFMGQLLDFERSL-RLEERHS---QEQGSGGQASAASNP--PSFFTTPTSDG 377
+S PN FM QL ++E L ++RH+ ++Q +P P F T DG
Sbjct: 427 RSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQPVDDPAGPGDFLPETPDG 486
Query: 378 AFE 380
E
Sbjct: 487 TPE 489
>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
Length = 703
Score = 103 bits (258), Expect = 2e-22
Identities = 69/183 (37%), Positives = 97/183 (53%), Gaps = 8/183 (4%)
Query: 204 PVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQ 263
P I +LYLGS +++NLE L G+ YILNVT + NFF G F Y I + D +
Sbjct: 320 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFP--GLFAYHNIRVYDEETT 377
Query: 264 NLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRK 323
+L + EA FI++A + LVHC GVSRS + +AY M++ L AY+ VK+K
Sbjct: 378 DLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQK 437
Query: 324 KSNISPNFNFMGQLLDFERSL-RLEERHS---QEQGSGGQASAASNP--PSFFTTPTSDG 377
+S PN FM QL ++E L ++RH+ ++Q +P P F T DG
Sbjct: 438 RSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQPVDDPAGPGDFLPETPDG 497
Query: 378 AFE 380
E
Sbjct: 498 TPE 500
>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
Length = 692
Score = 103 bits (258), Expect = 2e-22
Identities = 69/183 (37%), Positives = 97/183 (53%), Gaps = 8/183 (4%)
Query: 204 PVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQ 263
P I +LYLGS +++NLE L G+ YILNVT + NFF G F Y I + D +
Sbjct: 309 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFP--GLFAYHNIRVYDEETT 366
Query: 264 NLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRK 323
+L + EA FI++A + LVHC GVSRS + +AY M++ L AY+ VK+K
Sbjct: 367 DLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQK 426
Query: 324 KSNISPNFNFMGQLLDFERSL-RLEERHS---QEQGSGGQASAASNP--PSFFTTPTSDG 377
+S PN FM QL ++E L ++RH+ ++Q +P P F T DG
Sbjct: 427 RSITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQPVDDPAGPGDFLPETPDG 486
Query: 378 AFE 380
E
Sbjct: 487 TPE 489
>gi|37674210 slingshot 2 [Homo sapiens]
Length = 1423
Score = 103 bits (258), Expect = 2e-22
Identities = 57/150 (38%), Positives = 90/150 (60%), Gaps = 3/150 (2%)
Query: 204 PVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQ 263
P QI +++LGS +++NLE L G+RYILNVT + NFF G F Y I + D +
Sbjct: 308 PTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFP--GVFEYHNIRVYDEEAT 365
Query: 264 NLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRK 323
+L ++ + +FI +A LVHC GVSRS + +AY M++ +L+ AYD VK +
Sbjct: 366 DLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKER 425
Query: 324 KSNISPNFNFMGQLLDFER-SLRLEERHSQ 352
++ PN +FM QL +++ L ++RH++
Sbjct: 426 RTVTKPNPSFMRQLEEYQGILLASKQRHNK 455
>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
Length = 184
Score = 97.4 bits (241), Expect = 2e-20
Identities = 56/137 (40%), Positives = 80/137 (58%), Gaps = 3/137 (2%)
Query: 206 QILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNL 265
+ILP LY+G+ +D+ + E L+K + +IL+V + E Y IP +D SQNL
Sbjct: 7 KILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLE---GVKYLCIPAADSPSQNL 63
Query: 266 SRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKS 325
+R F E+I+FI E + LVHCLAGVSRSVT+ +AY+M DA V+ +S
Sbjct: 64 TRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRS 123
Query: 326 NISPNFNFMGQLLDFER 342
+PN F QL +FE+
Sbjct: 124 CANPNVGFQRQLQEFEK 140
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 94.4 bits (233), Expect = 2e-19
Identities = 55/135 (40%), Positives = 76/135 (56%), Gaps = 2/135 (1%)
Query: 207 ILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNLS 266
I P L LGS + +L++L K + +ILNV + N F DF YK I I D N+
Sbjct: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLS--DFTYKSISILDLPETNIL 126
Query: 267 RFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSN 326
+FPE EFI+EA ++ VLVHC AGVSR+ + + +LM S A+ LVK + +
Sbjct: 127 SYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPS 186
Query: 327 ISPNFNFMGQLLDFE 341
I PN FM QL ++
Sbjct: 187 ICPNSGFMEQLRTYQ 201
>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
Length = 198
Score = 89.0 bits (219), Expect = 7e-18
Identities = 51/139 (36%), Positives = 77/139 (55%), Gaps = 2/139 (1%)
Query: 206 QILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNL 265
QI +L+LG ++N L GI I+N T +PNF F Y ++P++D +
Sbjct: 29 QITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNF--NWPQFEYVKVPLADMPHAPI 86
Query: 266 SRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKS 325
+F + I ++ LVHC AGVSRS T+ +AYLM+ ++ L +AY+ VK ++
Sbjct: 87 GLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRP 146
Query: 326 NISPNFNFMGQLLDFERSL 344
I PN F QL+D+ER L
Sbjct: 147 VIRPNVGFWRQLIDYERQL 165
>gi|239582767 slingshot homolog 3 [Homo sapiens]
Length = 659
Score = 87.8 bits (216), Expect = 1e-17
Identities = 59/169 (34%), Positives = 86/169 (50%), Gaps = 4/169 (2%)
Query: 206 QILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNL 265
+I P+LYLGS ++ANLE L + + +ILN+ + NF+ + F Y + + D S L
Sbjct: 331 RIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPER--FTYHNVRLWDEESAQL 388
Query: 266 SRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKS 325
+ E FI+ A +Q VLVHC GVSRS +AY M++ SL A V+ +
Sbjct: 389 LPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRP 448
Query: 326 NISPNFNFMGQLLDFERSLRL-EERHSQEQGSGGQASAASNPPSFFTTP 373
PN F+ QL ++ L + H EQ GG S +P +TP
Sbjct: 449 IARPNPGFLRQLQIYQGILTASRQSHVWEQKVGG-VSPEEHPAPEVSTP 496
>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
sapiens]
Length = 223
Score = 87.4 bits (215), Expect = 2e-17
Identities = 53/141 (37%), Positives = 81/141 (57%), Gaps = 5/141 (3%)
Query: 206 QILPNLYLG--SARDSANLESLAKLGIRYILNVTPNLP-NFFEKNGD--FHYKQIPISDH 260
+ILP L+LG S+ + L L K GI +I+ + N+ NF + N F Y + I+D+
Sbjct: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
Query: 261 WSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLV 320
+N+ RFFP EFID +L VLVH AG+SRS +AY+M+ + DA+ V
Sbjct: 91 PVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV 150
Query: 321 KRKKSNISPNFNFMGQLLDFE 341
+ ++ I+PN F+ QL ++E
Sbjct: 151 QERRFCINPNAGFVHQLQEYE 171
>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 87.4 bits (215), Expect = 2e-17
Identities = 53/141 (37%), Positives = 81/141 (57%), Gaps = 5/141 (3%)
Query: 206 QILPNLYLG--SARDSANLESLAKLGIRYILNVTPNLP-NFFEKNGD--FHYKQIPISDH 260
+ILP L+LG S+ + L L K GI +I+ + N+ NF + N F Y + I+D+
Sbjct: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
Query: 261 WSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLV 320
+N+ RFFP EFID +L VLVH AG+SRS +AY+M+ + DA+ V
Sbjct: 91 PVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV 150
Query: 321 KRKKSNISPNFNFMGQLLDFE 341
+ ++ I+PN F+ QL ++E
Sbjct: 151 QERRFCINPNAGFVHQLQEYE 171
>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 87.4 bits (215), Expect = 2e-17
Identities = 53/141 (37%), Positives = 81/141 (57%), Gaps = 5/141 (3%)
Query: 206 QILPNLYLG--SARDSANLESLAKLGIRYILNVTPNLP-NFFEKNGD--FHYKQIPISDH 260
+ILP L+LG S+ + L L K GI +I+ + N+ NF + N F Y + I+D+
Sbjct: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
Query: 261 WSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLV 320
+N+ RFFP EFID +L VLVH AG+SRS +AY+M+ + DA+ V
Sbjct: 91 PVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV 150
Query: 321 KRKKSNISPNFNFMGQLLDFE 341
+ ++ I+PN F+ QL ++E
Sbjct: 151 QERRFCINPNAGFVHQLQEYE 171
>gi|4758208 dual specificity phosphatase 3 [Homo sapiens]
Length = 185
Score = 87.0 bits (214), Expect = 3e-17
Identities = 54/150 (36%), Positives = 78/150 (52%), Gaps = 9/150 (6%)
Query: 206 QILPNLYLGSARDSANLESLAKLGIRYILNVTP-------NLPNFFEKNGDFHYKQIPIS 258
++ P +Y+G+A + ++ L KLGI ++LN N F K+ Y I +
Sbjct: 32 EVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKAN 91
Query: 259 DHWSQNLSRFFPEAIEFIDEALSQNCG-VLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAY 317
D NLS +F A +FID+AL+Q G VLVHC G SRS T+ +AYLM + + + A
Sbjct: 92 DTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSAL 151
Query: 318 DLVKRKKSNISPNFNFMGQLLDFERSLRLE 347
+V R+ I PN F+ QL L E
Sbjct: 152 SIV-RQNREIGPNDGFLAQLCQLNDRLAKE 180
>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
Length = 211
Score = 82.4 bits (202), Expect = 6e-16
Identities = 57/145 (39%), Positives = 79/145 (54%), Gaps = 7/145 (4%)
Query: 206 QILPNLYLGSARDSANLESLAKLGIRYILNVTPN----LPNFFEKNGDFHYKQIPISDHW 261
++ P LYLG + N L +LGI ++LN + + P +E G Y + D
Sbjct: 64 EVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLG-IRYLGVEAHDSP 122
Query: 262 SQNLSRFFPEAIEFIDEALSQNCG-VLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLV 320
+ ++S F A +FI ALSQ G +LVHC GVSRS T+ +AYLM HL+L +A V
Sbjct: 123 AFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKV 182
Query: 321 KRKKSNISPNFNFMGQLLDFERSLR 345
K + I PN F+ QLL +R LR
Sbjct: 183 KDHR-GIIPNRGFLRQLLALDRRLR 206
>gi|56117818 muscle-restricted dual specificity phosphatase isoform
1 [Homo sapiens]
Length = 188
Score = 77.8 bits (190), Expect = 2e-14
Identities = 52/147 (35%), Positives = 77/147 (52%), Gaps = 10/147 (6%)
Query: 206 QILPNLYLGSARDSANLESLAKLGIRYILNVT------PNLPNFFEKNGDFHYKQIPISD 259
++ PNL++G A + N L KLGI ++LN P+F+ Y +P D
Sbjct: 40 EVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFY--GSSVSYLGVPAHD 97
Query: 260 HWSQNLSRFFPEAIEFIDEALSQ-NCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYD 318
++S +F A +FI AL+ VLVHC+ GVSRS T+ +AYLM LSL A
Sbjct: 98 LPDFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVI 157
Query: 319 LVKRKKSNISPNFNFMGQLLDFERSLR 345
V++ + + PN F+ QL ++ LR
Sbjct: 158 TVRQHRW-VFPNRGFLHQLCRLDQQLR 183
>gi|51491914 dual specificity phosphatase and pro isomerase domain
containing 1 [Homo sapiens]
Length = 220
Score = 77.0 bits (188), Expect = 3e-14
Identities = 51/155 (32%), Positives = 79/155 (50%), Gaps = 7/155 (4%)
Query: 206 QILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNF-----FEKNGDFHYKQIPISDH 260
++ P LY+G + + L K G ++LN N + ++ D Y + D
Sbjct: 57 EVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDL 116
Query: 261 WSQNLSRFFPEAIEFIDEALSQNCG-VLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDL 319
+ +LS FF A FID ALS + +LVHC+ G SRS T+ +AYLM ++L DA
Sbjct: 117 PTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQ 176
Query: 320 VKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQ 354
V + + + PN F+ QL + ++ L + R SQ Q
Sbjct: 177 VAKNRC-VLPNRGFLKQLRELDKQLVQQRRRSQRQ 210
>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
sapiens]
Length = 235
Score = 76.3 bits (186), Expect = 4e-14
Identities = 49/153 (32%), Positives = 77/153 (50%), Gaps = 9/153 (5%)
Query: 206 QILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNL 265
++LP LYLG+ D+ +L+ L + I +I+++ + + D Y +IP++D +
Sbjct: 7 KVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQ---DITYLRIPVADTPEVPI 63
Query: 266 SRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKS 325
+ F E I FI LVHC AG+SRS T+ AY+M L D + +K +
Sbjct: 64 KKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRP 123
Query: 326 NISPNFNFMGQLLDF----ERSLR--LEERHSQ 352
+PN F QL +F + LR LEER +
Sbjct: 124 IANPNPGFRQQLEEFGWASSQKLRRQLEERFGE 156
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,480,937
Number of Sequences: 37866
Number of extensions: 887818
Number of successful extensions: 6911
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 66
Number of HSP's successfully gapped in prelim test: 75
Number of HSP's that attempted gapping in prelim test: 6541
Number of HSP's gapped (non-prelim): 332
length of query: 384
length of database: 18,247,518
effective HSP length: 104
effective length of query: 280
effective length of database: 14,309,454
effective search space: 4006647120
effective search space used: 4006647120
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.