Guide to the Human Genome
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Search of human proteins with 4503363

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503363 dolichyl-phosphate mannosyltransferase 1 [Homo
sapiens]
         (260 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503363 dolichyl-phosphate mannosyltransferase 1 [Homo sapiens]    516   e-147
gi|7019323 dolichyl-phosphate beta-glucosyltransferase isoform 1...    73   3e-13
gi|215276969 dolichyl-phosphate beta-glucosyltransferase isoform...    45   6e-05
gi|190014583 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-ac...    35   0.050
gi|153792095 N-acetylgalactosaminyltransferase 11 [Homo sapiens]       34   0.15 
gi|71043692 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-ace...    32   0.42 
gi|8393412 polypeptide N-acetylgalactosaminyltransferase 8 [Homo...    31   0.95 
gi|94536811 NEDD4-like ubiquitin-protein ligase 1 [Homo sapiens]       31   1.2  
gi|34452725 polypeptide N-acetylgalactosaminyltransferase 4 [Hom...    31   1.2  
gi|73476319 hypothetical protein LOC352909 [Homo sapiens]              30   2.8  
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa...    28   6.1  
gi|60498976 N-acetylgalactosaminyltransferase 14 [Homo sapiens]        28   8.0  
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ...    28   8.0  
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ...    28   8.0  
gi|158420731 chromodomain helicase DNA binding protein 3 isoform...    28   8.0  

>gi|4503363 dolichyl-phosphate mannosyltransferase 1 [Homo sapiens]
          Length = 260

 Score =  516 bits (1330), Expect = e-147
 Identities = 260/260 (100%), Positives = 260/260 (100%)

Query: 1   MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEI 60
           MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEI
Sbjct: 1   MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEI 60

Query: 61  IIIDDGSPDGTRDVAEQLEKIYGSDRILLRPREKKLGLGTAYIHGMKHATGNYIIIMDAD 120
           IIIDDGSPDGTRDVAEQLEKIYGSDRILLRPREKKLGLGTAYIHGMKHATGNYIIIMDAD
Sbjct: 61  IIIDDGSPDGTRDVAEQLEKIYGSDRILLRPREKKLGLGTAYIHGMKHATGNYIIIMDAD 120

Query: 121 LSHHPKFIPEFIRKQKEGNFDIVSGTRYKGNGGVYGWDLKRKIISRGANFLTQILLRPGA 180
           LSHHPKFIPEFIRKQKEGNFDIVSGTRYKGNGGVYGWDLKRKIISRGANFLTQILLRPGA
Sbjct: 121 LSHHPKFIPEFIRKQKEGNFDIVSGTRYKGNGGVYGWDLKRKIISRGANFLTQILLRPGA 180

Query: 181 SDLTGSFRLYRKEVLEKLIEKCVSKGYVFQMEMIVRARQLNYTIGEVPISFVDRVYGESK 240
           SDLTGSFRLYRKEVLEKLIEKCVSKGYVFQMEMIVRARQLNYTIGEVPISFVDRVYGESK
Sbjct: 181 SDLTGSFRLYRKEVLEKLIEKCVSKGYVFQMEMIVRARQLNYTIGEVPISFVDRVYGESK 240

Query: 241 LGGNEIVSFLKGLLTLFATT 260
           LGGNEIVSFLKGLLTLFATT
Sbjct: 241 LGGNEIVSFLKGLLTLFATT 260


>gi|7019323 dolichyl-phosphate beta-glucosyltransferase isoform 1
           [Homo sapiens]
          Length = 324

 Score = 72.8 bits (177), Expect = 3e-13
 Identities = 60/236 (25%), Positives = 112/236 (47%), Gaps = 24/236 (10%)

Query: 28  SVLLPTYNERENLPLIV-----WLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIY 82
           SV++P+YNE + LP+++     +L  +   +    YE+I++DDGS D T  VA +  + Y
Sbjct: 68  SVVVPSYNEEKRLPVMMDEALSYLEKRQKRDPAFTYEVIVVDDGSKDQTSKVAFKYCQKY 127

Query: 83  GSDRILLRPREKKLGLGTAYIHGMKHATGNYIIIMDADLSHHPKFIPEFIRKQKEGN--- 139
           GSD++ +    K  G G A   G+  + G  I++ DAD +   KF P+  + +K  N   
Sbjct: 128 GSDKVRVITLVKNRGKGGAIRMGIFSSRGEKILMADADGA--TKF-PDVEKLEKGLNDLQ 184

Query: 140 -----FDIVSGTR-YKGNGGVYGWDLKRKIISRGANFLTQILLRPGASDLTGSFRLYRKE 193
                  I  G+R +     +      R ++  G +FL   L   G  D    F+L+ +E
Sbjct: 185 PWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKLFTRE 244

Query: 194 VLEKLIEKCVSKGYVFQMEMIVRARQLNYTIGEVPISFVDRVYGESKLGGNEIVSF 249
              +       + + F +E++  A+     I E+ +++       +++ G+++V F
Sbjct: 245 AASRTFSSLHVERWAFDVELLYIAQFFKIPIAEIAVNW-------TEIEGSKLVPF 293


>gi|215276969 dolichyl-phosphate beta-glucosyltransferase isoform 2
           [Homo sapiens]
          Length = 294

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 51/231 (22%), Positives = 97/231 (41%), Gaps = 44/231 (19%)

Query: 28  SVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRI 87
           SV++P+YNE + LP+++                        D      E+ +K YGSD++
Sbjct: 68  SVVVPSYNEEKRLPVMM------------------------DEALSYLEKRQK-YGSDKV 102

Query: 88  LLRPREKKLGLGTAYIHGMKHATGNYIIIMDADLSHHPKFIPEFIRKQKEGN-------- 139
            +    K  G G A   G+  + G  I++ DAD +   KF P+  + +K  N        
Sbjct: 103 RVITLVKNRGKGGAIRMGIFSSRGEKILMADADGA--TKF-PDVEKLEKGLNDLQPWPNQ 159

Query: 140 FDIVSGTR-YKGNGGVYGWDLKRKIISRGANFLTQILLRPGASDLTGSFRLYRKEVLEKL 198
             I  G+R +     +      R ++  G +FL   L   G  D    F+L+ +E   + 
Sbjct: 160 MAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKLFTREAASRT 219

Query: 199 IEKCVSKGYVFQMEMIVRARQLNYTIGEVPISFVDRVYGESKLGGNEIVSF 249
                 + + F +E++  A+     I E+ +++       +++ G+++V F
Sbjct: 220 FSSLHVERWAFDVELLYIAQFFKIPIAEIAVNW-------TEIEGSKLVPF 263


>gi|190014583 UDP-N-acetyl-alpha-D-galactosamine:polypeptide
           N-acetylgalactosaminyltransferase-like 2 [Homo sapiens]
          Length = 639

 Score = 35.4 bits (80), Expect = 0.050
 Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 1/76 (1%)

Query: 59  EIIIIDDGSPDGTRDVAEQLEKIYGSDRILLRPREKKLGLGTAYIHGMKHATGNYIIIMD 118
           EII++DD S  G    A   E +   + + L    K+LG   A + G   ATG+ ++ MD
Sbjct: 225 EIILVDDLSQQGQLKSALS-EYVARLEGVKLLRSNKRLGAIRARMLGATRATGDVLVFMD 283

Query: 119 ADLSHHPKFIPEFIRK 134
           A    HP ++   + +
Sbjct: 284 AHCECHPGWLEPLLSR 299


>gi|153792095 N-acetylgalactosaminyltransferase 11 [Homo sapiens]
          Length = 608

 Score = 33.9 bits (76), Expect = 0.15
 Identities = 27/117 (23%), Positives = 54/117 (46%), Gaps = 1/117 (0%)

Query: 28  SVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSP-DGTRDVAEQLEKIYGSDR 86
           SV++  YNE  +  L     V   + + + +EII++DD S  D  +   ++  + Y   +
Sbjct: 154 SVVICFYNEAFSALLRTVHSVIDRTPAHLLHEIILVDDDSDFDDLKGELDEYVQKYLPGK 213

Query: 87  ILLRPREKKLGLGTAYIHGMKHATGNYIIIMDADLSHHPKFIPEFIRKQKEGNFDIV 143
           I +    K+ GL    + G  HATG  ++ +D+    +  ++   +   +E    +V
Sbjct: 214 IKVIRNTKREGLIRGRMIGAAHATGEVLVFLDSHCEVNVMWLQPLLAAIREDRHTVV 270


>gi|71043692 UDP-N-acetyl-alpha-D-galactosamine:polypeptide
           N-acetylgalactosaminyltransferase-like 1 [Homo sapiens]
          Length = 558

 Score = 32.3 bits (72), Expect = 0.42
 Identities = 24/117 (20%), Positives = 54/117 (46%), Gaps = 5/117 (4%)

Query: 28  SVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRI 87
           SV++  +NE  +  L     V + + + +  EII++DD S D      E    +    ++
Sbjct: 126 SVIITFHNEARSTLLRTVKSVLNRTPANLIQEIILVDDFSSD-----PEDCLLLTRIPKV 180

Query: 88  LLRPREKKLGLGTAYIHGMKHATGNYIIIMDADLSHHPKFIPEFIRKQKEGNFDIVS 144
                +++ GL  + + G   A    +  +D+    + +++P  +++ KE +  +VS
Sbjct: 181 KCLRNDRREGLIRSRVRGADMAAATVLTFLDSHCEVNTEWLPPMLQRVKEDHTRVVS 237


>gi|8393412 polypeptide N-acetylgalactosaminyltransferase 8 [Homo
           sapiens]
          Length = 637

 Score = 31.2 bits (69), Expect = 0.95
 Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 8/123 (6%)

Query: 28  SVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDV-AEQLEKIY---- 82
           SV+L   NE  ++       + + + S +  EII++DD S +G   V  ++  K+Y    
Sbjct: 184 SVILIFVNEALSIIQRAITSIINRTPSRLLKEIILVDDFSSNGELKVHLDEKIKLYNQKY 243

Query: 83  -GSDRILLRPREKKLGLGTAYIHGMKHATGNYIIIMDADLSHHPKFIPEFIRKQKEGNFD 141
            G  +I+  P  K  GL  A   G + AT + + I+DA +  +  +    + + +E    
Sbjct: 244 PGLLKIIRHPERK--GLAQARNTGWEAATADVVAILDAHIEVNVGWAEPILARIQEDRTV 301

Query: 142 IVS 144
           IVS
Sbjct: 302 IVS 304


>gi|94536811 NEDD4-like ubiquitin-protein ligase 1 [Homo sapiens]
          Length = 1606

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 24/98 (24%), Positives = 47/98 (47%), Gaps = 14/98 (14%)

Query: 119  ADLSHHPKFIPEFIRKQKEGNFDIVSGTRYKGNGGVYGWDLKRKIISRGANFLTQILLRP 178
            +DL +  +   + ++  K+ N   +    +  N  V+G   +R++ S GAN  TQ+  + 
Sbjct: 1378 SDLEYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQVTERELKSGGAN--TQVTEKN 1435

Query: 179  GASDLTGSFRLYRKEVLEKLIEKCVSKGYVFQMEMIVR 216
                        +KE +E++++  V +G V Q E +VR
Sbjct: 1436 ------------KKEYIERMVKWRVERGVVQQTEALVR 1461


>gi|34452725 polypeptide N-acetylgalactosaminyltransferase 4 [Homo
           sapiens]
          Length = 578

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 3/92 (3%)

Query: 28  SVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEK-IYGSDR 86
           SV++  YNE  +  L     V   S + +  EII++DD S      +  QLE  I   DR
Sbjct: 138 SVIIAFYNEAWSTLLRTIHSVLETSPAVLLKEIILVDDLSDRVY--LKTQLETYISNLDR 195

Query: 87  ILLRPREKKLGLGTAYIHGMKHATGNYIIIMD 118
           + L    K+ GL  A + G   ATG+ +  +D
Sbjct: 196 VRLIRTNKREGLVRARLIGATFATGDVLTFLD 227


>gi|73476319 hypothetical protein LOC352909 [Homo sapiens]
          Length = 588

 Score = 29.6 bits (65), Expect = 2.8
 Identities = 12/27 (44%), Positives = 16/27 (59%)

Query: 145 GTRYKGNGGVYGWDLKRKIISRGANFL 171
           G+RY    GV  WDL+ K+  RGA  +
Sbjct: 246 GSRYDARRGVSDWDLRMKLHDRGAQVI 272


>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
            sapiens]
          Length = 1912

 Score = 28.5 bits (62), Expect = 6.1
 Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 4/82 (4%)

Query: 105  GMKHATGNYIIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTRYKGNGGVYGWDLKRKII 164
            G+  AT + +II D+D + H   I  F R  + G    V   R+     V   + +   +
Sbjct: 1132 GINLATADTVIIYDSDWNPHND-IQAFSRAHRIGQNKKVMIYRFVTRASV---EERITQV 1187

Query: 165  SRGANFLTQILLRPGASDLTGS 186
            ++    LT +++RPG    TGS
Sbjct: 1188 AKKKMMLTHLVVRPGLGSKTGS 1209


>gi|60498976 N-acetylgalactosaminyltransferase 14 [Homo sapiens]
          Length = 552

 Score = 28.1 bits (61), Expect = 8.0
 Identities = 25/110 (22%), Positives = 51/110 (46%), Gaps = 5/110 (4%)

Query: 28  SVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRI 87
           S+++  +NE  +  L     V + + + +  EII++DD S D   D  +QL K+    ++
Sbjct: 114 SIIITFHNEARSTLLRTIRSVLNRTPTHLIREIILVDDFSND--PDDCKQLIKL---PKV 168

Query: 88  LLRPREKKLGLGTAYIHGMKHATGNYIIIMDADLSHHPKFIPEFIRKQKE 137
                 ++ GL  + I G   A G  +  +D+    +  ++   + + KE
Sbjct: 169 KCLRNNERQGLVRSRIRGADIAQGTTLTFLDSHCEVNRDWLQPLLHRVKE 218


>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
            [Homo sapiens]
          Length = 2000

 Score = 28.1 bits (61), Expect = 8.0
 Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 4/82 (4%)

Query: 105  GMKHATGNYIIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTRYKGNGGVYGWDLKRKII 164
            G+  AT + +II D+D + H   I  F R  + G  + V   R+     V   + +   +
Sbjct: 1142 GINLATADTVIIFDSDWNPH-NDIQAFSRAHRIGQANKVMIYRFVTRASV---EERITQV 1197

Query: 165  SRGANFLTQILLRPGASDLTGS 186
            ++    LT +++RPG     GS
Sbjct: 1198 AKRKMMLTHLVVRPGLGSKAGS 1219


>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
            [Homo sapiens]
          Length = 1966

 Score = 28.1 bits (61), Expect = 8.0
 Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 4/82 (4%)

Query: 105  GMKHATGNYIIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTRYKGNGGVYGWDLKRKII 164
            G+  AT + +II D+D + H   I  F R  + G  + V   R+     V   + +   +
Sbjct: 1142 GINLATADTVIIFDSDWNPH-NDIQAFSRAHRIGQANKVMIYRFVTRASV---EERITQV 1197

Query: 165  SRGANFLTQILLRPGASDLTGS 186
            ++    LT +++RPG     GS
Sbjct: 1198 AKRKMMLTHLVVRPGLGSKAGS 1219


>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
            [Homo sapiens]
          Length = 2059

 Score = 28.1 bits (61), Expect = 8.0
 Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 4/82 (4%)

Query: 105  GMKHATGNYIIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTRYKGNGGVYGWDLKRKII 164
            G+  AT + +II D+D + H   I  F R  + G  + V   R+     V   + +   +
Sbjct: 1201 GINLATADTVIIFDSDWNPH-NDIQAFSRAHRIGQANKVMIYRFVTRASV---EERITQV 1256

Query: 165  SRGANFLTQILLRPGASDLTGS 186
            ++    LT +++RPG     GS
Sbjct: 1257 AKRKMMLTHLVVRPGLGSKAGS 1278


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.140    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,323,905
Number of Sequences: 37866
Number of extensions: 403062
Number of successful extensions: 765
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 754
Number of HSP's gapped (non-prelim): 15
length of query: 260
length of database: 18,247,518
effective HSP length: 100
effective length of query: 160
effective length of database: 14,460,918
effective search space: 2313746880
effective search space used: 2313746880
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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