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Search of human proteins with 4503137
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503137 chymotrypsin-like [Homo sapiens]
(264 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503137 chymotrypsin-like [Homo sapiens] 544 e-155
gi|118498350 chymotrypsin B2 [Homo sapiens] 310 8e-85
gi|118498341 chymotrypsin B1 [Homo sapiens] 306 2e-83
gi|15559207 elastase 2A preproprotein [Homo sapiens] 202 2e-52
gi|6679625 elastase 3B, pancreatic preproprotein [Homo sapiens] 197 8e-51
gi|58331211 elastase 2B preproprotein [Homo sapiens] 190 1e-48
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 182 2e-46
gi|236460050 elastase 3A, pancreatic preproprotein [Homo sapiens] 182 3e-46
gi|62526043 chymotrypsin C preproprotein [Homo sapiens] 180 1e-45
gi|4505881 plasminogen [Homo sapiens] 179 2e-45
gi|4506153 prostasin preproprotein [Homo sapiens] 177 1e-44
gi|58331209 chymotrypsin-like elastase family, member 1 [Homo sa... 170 1e-42
gi|223942069 enterokinase precursor [Homo sapiens] 169 2e-42
gi|110815798 ovochymase 1 [Homo sapiens] 169 2e-42
gi|33695155 hepsin [Homo sapiens] 167 9e-42
gi|4504481 hepsin [Homo sapiens] 167 9e-42
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 165 3e-41
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens] 164 6e-41
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 162 2e-40
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 162 2e-40
gi|68508970 tryptase beta 2 precursor [Homo sapiens] 162 2e-40
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens] 161 6e-40
gi|13994276 marapsin [Homo sapiens] 161 6e-40
gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 161 6e-40
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 160 8e-40
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 159 2e-39
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 159 3e-39
gi|29244926 corin [Homo sapiens] 158 5e-39
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] 158 5e-39
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 157 9e-39
>gi|4503137 chymotrypsin-like [Homo sapiens]
Length = 264
Score = 544 bits (1401), Expect = e-155
Identities = 264/264 (100%), Positives = 264/264 (100%)
Query: 1 MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFC 60
MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFC
Sbjct: 1 MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFC 60
Query: 61 GGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNN 120
GGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNN
Sbjct: 61 GGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNN 120
Query: 121 DVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALP 180
DVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALP
Sbjct: 121 DVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALP 180
Query: 181 LVTVNQCRQYWGSSITDSMICAGGAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCN 240
LVTVNQCRQYWGSSITDSMICAGGAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCN
Sbjct: 181 LVTVNQCRQYWGSSITDSMICAGGAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCN 240
Query: 241 VRAPAVYTRVSKFSTWINQVIAYN 264
VRAPAVYTRVSKFSTWINQVIAYN
Sbjct: 241 VRAPAVYTRVSKFSTWINQVIAYN 264
>gi|118498350 chymotrypsin B2 [Homo sapiens]
Length = 263
Score = 310 bits (794), Expect = 8e-85
Identities = 144/264 (54%), Positives = 187/264 (70%), Gaps = 1/264 (0%)
Query: 1 MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFC 60
M L L LLG+++GCG+PAI P LS RIVNGE+AV GSWPWQVSLQD +GFHFC
Sbjct: 1 MAFLWLLSCWALLGTTFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTGFHFC 60
Query: 61 GGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNN 120
GGSLIS+ WVVTAAHC V VV GE+D+ S+ E +QVL +++ +P ++ T+NN
Sbjct: 61 GGSLISEDWVVTAAHCGVRTS-DVVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTVNN 119
Query: 121 DVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALP 180
D+TLLKLA+PA+++ +S VCL S+++ G C TTGWG+ N TP LQQ ALP
Sbjct: 120 DITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALP 179
Query: 181 LVTVNQCRQYWGSSITDSMICAGGAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCN 240
L++ +C++ WG ITD MICAG +G SSC GDSGGPLVCQK W L+GIVSWG++ C+
Sbjct: 180 LLSNAECKKSWGRRITDVMICAGASGVSSCMGDSGGPLVCQKDGAWTLVGIVSWGSRTCS 239
Query: 241 VRAPAVYTRVSKFSTWINQVIAYN 264
PAVY RV+K W+ +++A N
Sbjct: 240 TTTPAVYARVAKLIPWVQKILAAN 263
>gi|118498341 chymotrypsin B1 [Homo sapiens]
Length = 263
Score = 306 bits (783), Expect = 2e-83
Identities = 142/264 (53%), Positives = 186/264 (70%), Gaps = 1/264 (0%)
Query: 1 MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFC 60
M L L L+G+++GCG+PAI P LS RIVNGE+AV GSWPWQVSLQD +GFHFC
Sbjct: 1 MASLWLLSCFSLVGAAFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTGFHFC 60
Query: 61 GGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNN 120
GGSLIS+ WVVTAAHC V VV GE+D+ S+ E +QVL +++ +P ++ T+NN
Sbjct: 61 GGSLISEDWVVTAAHCGVRTS-DVVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTVNN 119
Query: 121 DVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALP 180
D+TLLKLA+PA+++ +S VCL S+++ G C TTGWG+ N TP LQQ ALP
Sbjct: 120 DITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALP 179
Query: 181 LVTVNQCRQYWGSSITDSMICAGGAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCN 240
L++ +C++ WG ITD MICAG +G SSC GDSGGPLVCQK W L+GIVSWG+ C+
Sbjct: 180 LLSNAECKKSWGRRITDVMICAGASGVSSCMGDSGGPLVCQKDGAWTLVGIVSWGSDTCS 239
Query: 241 VRAPAVYTRVSKFSTWINQVIAYN 264
+P VY RV+K W+ +++A N
Sbjct: 240 TSSPGVYARVTKLIPWVQKILAAN 263
>gi|15559207 elastase 2A preproprotein [Homo sapiens]
Length = 269
Score = 202 bits (514), Expect = 2e-52
Identities = 124/274 (45%), Positives = 159/274 (58%), Gaps = 16/274 (5%)
Query: 2 LLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSG---FH 58
++ +L LS ++ G+ CG P P ++ R+V GE A SWPWQVSLQ SS +H
Sbjct: 1 MIRTLLLSTLVAGAL-SCGDPTYPPYVT---RVVGGEEARPNSWPWQVSLQYSSNGKWYH 56
Query: 59 FCGGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTM 118
CGGSLI+ SWV+TAAHC S + V LG ++ +SVS+ + H WNS +
Sbjct: 57 TCGGSLIANSWVLTAAHCISSSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQI 116
Query: 119 N--NDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQ 176
+ ND+ LLKLA+P T +I CL + L C TGWGRL G V P LQQ
Sbjct: 117 SKGNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAV-PDVLQQ 175
Query: 177 VALPLVTVNQCRQ--YWGSSITDSMICAGGAGA-SSCQGDSGGPLVCQKGN-TWVLIGIV 232
L +V C +WGSS+ SMICAGG G SSC GDSGGPL CQ + W + GIV
Sbjct: 176 GRLLVVDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIV 235
Query: 233 SWGTK-NCN-VRAPAVYTRVSKFSTWINQVIAYN 264
S+G++ CN P+V+TRVS + WIN VIA N
Sbjct: 236 SFGSRLGCNYYHKPSVFTRVSNYIDWINSVIANN 269
>gi|6679625 elastase 3B, pancreatic preproprotein [Homo sapiens]
Length = 270
Score = 197 bits (501), Expect = 8e-51
Identities = 117/273 (42%), Positives = 155/273 (56%), Gaps = 17/273 (6%)
Query: 2 LLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQ---DSSGFH 58
++L L SL+L+ + G G P+ +P S R+VNGE+AV SWPWQVSLQ S +H
Sbjct: 1 MMLRLLSSLLLVAVASGYGPPSSRP----SSRVVNGEDAVPYSWPWQVSLQYEKSGSFYH 56
Query: 59 FCGGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRA--ITHPSWNST 116
CGGSLI+ WVVTA HC S + VVLGEYDR+ P QV+ ++ HP WN +
Sbjct: 57 TCGGSLIAPDWVVTAGHCISSSRTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRS 116
Query: 117 TM--NNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHL 174
+ ND+ L+KL+ AQ + L + + L C TGWGRL G + P L
Sbjct: 117 CVACGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNGPL-PDKL 175
Query: 175 QQVALPLVTVNQCRQ--YWGSSITDSMICAGGAGASSCQGDSGGPLVC-QKGNTWVLIGI 231
Q+ LP+V C + +WGSS+ +M+CAGG S C GDSGGPL C + W + G+
Sbjct: 176 QEALLPVVDYEHCSRWNWWGSSVKKTMVCAGGDIRSGCNGDSGGPLNCPTEDGGWQVHGV 235
Query: 232 VSW-GTKNCNV-RAPAVYTRVSKFSTWINQVIA 262
S+ CN R P V+TRVS F WI + IA
Sbjct: 236 TSFVSAFGCNTRRKPTVFTRVSAFIDWIEETIA 268
>gi|58331211 elastase 2B preproprotein [Homo sapiens]
Length = 269
Score = 190 bits (482), Expect = 1e-48
Identities = 115/274 (41%), Positives = 155/274 (56%), Gaps = 16/274 (5%)
Query: 2 LLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSG---FH 58
++ +L LS ++ G+ CG+ P +S R++ GE A SWPWQVSLQ SS +H
Sbjct: 1 MIRTLLLSTLVAGAL-SCGVSTYAPDMS---RMLGGEEARPNSWPWQVSLQYSSNGQWYH 56
Query: 59 FCGGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNS--T 116
CGGSLI+ SWV+TAAHC S G + V+LG+++ +SVS+ + H WNS
Sbjct: 57 TCGGSLIANSWVLTAAHCISSSGIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQV 116
Query: 117 TMNNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQ 176
+ ND+ LLKLA+P T +I CL + L C TGWGRL G P L+Q
Sbjct: 117 SKGNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNG-ALPDDLKQ 175
Query: 177 VALPLVTVNQCRQ--YWGSSITDSMICAGGAGA-SSCQGDSGGPLVCQKGN-TWVLIGIV 232
L +V C +WGS++ +MICAGG G +C GDSGGPL CQ + W + GI
Sbjct: 176 GRLLVVDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIG 235
Query: 233 S-WGTKNCN-VRAPAVYTRVSKFSTWINQVIAYN 264
S CN P+++TRVS ++ WIN VIA N
Sbjct: 236 SLTSVLGCNYYYKPSIFTRVSNYNDWINSVIANN 269
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 182 bits (463), Expect = 2e-46
Identities = 97/238 (40%), Positives = 132/238 (55%), Gaps = 12/238 (5%)
Query: 30 FSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAAHCNVS---PGRHFVV 86
+S RIV G ++L WPWQ SLQ G+H CGGS+I+ W++TAAHC P +
Sbjct: 213 YSSRIVGGNMSLLSQWPWQASLQ-FQGYHLCGGSVITPLWIITAAHCVYDLYLPKSWTIQ 271
Query: 87 LGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNNDVTLLKLASPAQYTTRISPVCLASSN 146
+G N P + V + + H + + ND+ L+KLA P + I PVCL +S
Sbjct: 272 VGLVSLLDNPAPSHL--VEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSE 329
Query: 147 EALTEGLTCVTTGWGRLS-GVGNVTPAHLQQVALPLVTVNQC--RQYWGSSITDSMICAG 203
E +G C T+GWG G G+ +P L A+PL++ C R +G I+ SM+CAG
Sbjct: 330 ENFPDGKVCWTSGWGATEDGAGDASPV-LNHAAVPLISNKICNHRDVYGGIISPSMLCAG 388
Query: 204 --GAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCNVRAPAVYTRVSKFSTWINQ 259
G SCQGDSGGPLVCQ+ W L+G S+G V P VYTRV+ F WI++
Sbjct: 389 YLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHE 446
>gi|236460050 elastase 3A, pancreatic preproprotein [Homo sapiens]
Length = 270
Score = 182 bits (462), Expect = 3e-46
Identities = 111/273 (40%), Positives = 151/273 (55%), Gaps = 17/273 (6%)
Query: 2 LLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQ---DSSGFH 58
++L L SL+L+ + G G P+ S R+V+GE+AV SWPWQVSLQ S +H
Sbjct: 1 MMLRLLSSLLLVAVASGYG----PPSSHSSSRVVHGEDAVPYSWPWQVSLQYEKSGSFYH 56
Query: 59 FCGGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVS--RAITHPSWNST 116
CGGSLI+ WVVTA HC + VVLGEY+ + P QV+ ++ HP WN +
Sbjct: 57 TCGGSLIAPDWVVTAGHCISRDLTYQVVLGEYNLAVKEGPEQVIPINSEELFVHPLWNRS 116
Query: 117 TM--NNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHL 174
+ ND+ L+KL+ AQ + L + + L C TGWGRL G + P L
Sbjct: 117 CVACGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNKTPCYITGWGRLYTNGPL-PDKL 175
Query: 175 QQVALPLVTVNQCRQ--YWGSSITDSMICAGGAGASSCQGDSGGPLVC-QKGNTWVLIGI 231
QQ LP+V C + +WGS++ +M+CAGG S C GDSGGPL C + W + G+
Sbjct: 176 QQARLPVVDYKHCSRWNWWGSTVKKTMVCAGGYIRSGCNGDSGGPLNCPTEDGGWQVHGV 235
Query: 232 VSW-GTKNCN-VRAPAVYTRVSKFSTWINQVIA 262
S+ CN + P V+TRVS F WI + IA
Sbjct: 236 TSFVSAFGCNFIWKPTVFTRVSAFIDWIEETIA 268
>gi|62526043 chymotrypsin C preproprotein [Homo sapiens]
Length = 268
Score = 180 bits (456), Expect = 1e-45
Identities = 105/267 (39%), Positives = 151/267 (56%), Gaps = 13/267 (4%)
Query: 3 LLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQ---DSSGFHF 59
+L +T+ LL + CG+P+ P LS R+V GE+A SWPWQ+SLQ + + H
Sbjct: 1 MLGITVLAALLACASSCGVPSFPPNLS--ARVVGGEDARPHSWPWQISLQYLKNDTWRHT 58
Query: 60 CGGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRS-SNAEPLQVLSVSRAITHPSWNSTTM 118
CGG+LI+ ++V+TAAHC + + V +G+ + + E + V H WN+ +
Sbjct: 59 CGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLL 118
Query: 119 NNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVA 178
ND+ L+KLA + + I CL + L + C TGWGRL G + LQQ
Sbjct: 119 RNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIAD-KLQQGL 177
Query: 179 LPLVTVNQCRQ--YWGSSITDSMICAGGAGA-SSCQGDSGGPLVCQKGN-TWVLIGIVSW 234
P+V C + +WG + +M+CAGG G S+C GDSGGPL CQ N +W + GIVS+
Sbjct: 178 QPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSF 237
Query: 235 GT-KNCNVR-APAVYTRVSKFSTWINQ 259
G+ + CN R P VYTRVS + WIN+
Sbjct: 238 GSRRGCNTRKKPVVYTRVSAYIDWINE 264
>gi|4505881 plasminogen [Homo sapiens]
Length = 810
Score = 179 bits (454), Expect = 2e-45
Identities = 100/256 (39%), Positives = 136/256 (53%), Gaps = 16/256 (6%)
Query: 16 SWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAAH 75
S+ CG P ++P R+V G A SWPWQVSL+ G HFCGG+LIS WV+TAAH
Sbjct: 564 SFDCGKPQVEPK-KCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAH 622
Query: 76 C---NVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNNDVTLLKLASPAQ 132
C + P + V+LG + + +Q + VSR P+ D+ LLKL+SPA
Sbjct: 623 CLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAV 676
Query: 133 YTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQCRQY-- 190
T ++ P CL S N + + C TGWG G L++ LP++ C +Y
Sbjct: 677 ITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGA--GLLKEAQLPVIENKVCNRYEF 734
Query: 191 WGSSITDSMICAG--GAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCNVRAPAVYT 248
+ + +CAG G SCQGDSGGPLVC + + ++L G+ SWG P VY
Sbjct: 735 LNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYV 794
Query: 249 RVSKFSTWINQVIAYN 264
RVS+F TWI V+ N
Sbjct: 795 RVSRFVTWIEGVMRNN 810
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 177 bits (448), Expect = 1e-44
Identities = 102/275 (37%), Positives = 144/275 (52%), Gaps = 21/275 (7%)
Query: 4 LSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGGS 63
+++ L L LL S G ++ RI G +AV G WPWQVS+ G H CGGS
Sbjct: 15 VAILLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSIT-YEGVHVCGGS 73
Query: 64 LISQSWVVTAAHCNVSPGRHF-----VVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTM 118
L+S+ WV++AAHC P H V LG + S +E +V ++ I HPS+
Sbjct: 74 LVSEQWVLSAAHC--FPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGS 131
Query: 119 NNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLS-GVGNVTPAHLQQV 177
D+ LL+L+ P ++ I P+CL ++N + GL C TGWG ++ V +TP LQQ+
Sbjct: 132 QGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQL 191
Query: 178 ALPLVTVNQCRQYWGSS--------ITDSMICAG--GAGASSCQGDSGGPLVCQKGNTWV 227
+PL++ C + + + M+CAG G +CQGDSGGPL C W
Sbjct: 192 EVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWY 251
Query: 228 LIGIVSWGTKNCNVR-APAVYTRVSKFSTWINQVI 261
L GIVSWG C R P VYT S +++WI +
Sbjct: 252 LTGIVSWGDA-CGARNRPGVYTLASSYASWIQSKV 285
>gi|58331209 chymotrypsin-like elastase family, member 1 [Homo
sapiens]
Length = 258
Score = 170 bits (431), Expect = 1e-42
Identities = 99/242 (40%), Positives = 133/242 (54%), Gaps = 11/242 (4%)
Query: 33 RIVNGENAVLGSWPWQVSLQDSSG---FHFCGGSLISQSWVVTAAHCNVSPGRHFVVLGE 89
R+V G A SWP Q+SLQ SG +H CGG+LI Q+WV+TAAHC VV G+
Sbjct: 18 RVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFRVVAGD 77
Query: 90 YDRSSNAEPLQVLSVSRAITHPSWNSTTM--NNDVTLLKLASPAQYTTRISPVCLASSNE 147
++ S N Q +SV + + HP WNS + D+ LL+LA + + L
Sbjct: 78 HNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLPQEGA 137
Query: 148 ALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQC--RQYWGSSITDSMICAGGA 205
L C TGWG+ G + LQQ LP V C YWGS++ ++M+CAGG
Sbjct: 138 ILANNSPCYITGWGKTKTNGQLAQT-LQQAYLPSVDYAICSSSSYWGSTVKNTMVCAGGD 196
Query: 206 GA-SSCQGDSGGPLVCQKGNTWVLIGIVSW-GTKNCNV-RAPAVYTRVSKFSTWINQVIA 262
G S CQGDSGGPL C + + G+ S+ ++ CNV R P V+T+VS + +WIN VIA
Sbjct: 197 GVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVIA 256
Query: 263 YN 264
N
Sbjct: 257 SN 258
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 169 bits (429), Expect = 2e-42
Identities = 92/243 (37%), Positives = 131/243 (53%), Gaps = 10/243 (4%)
Query: 27 ALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAAHC----NVSPGR 82
A + +IV G NA G+WPW V L G CG SL+S W+V+AAHC N+ P +
Sbjct: 778 AQDITPKIVGGSNAKEGAWPWVVGLY-YGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSK 836
Query: 83 HFVVLGEYDRSSNAEPLQVLS-VSRAITHPSWNSTTMNNDVTLLKLASPAQYTTRISPVC 141
+LG + +S+ P V + + +P +N +ND+ ++ L YT I P+C
Sbjct: 837 WTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPIC 896
Query: 142 LASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQCRQYWGS-SITDSMI 200
L N+ G C GWG + G T LQ+ +PL++ +C+Q +IT++MI
Sbjct: 897 LPEENQVFPPGRNCSIAGWGTVVYQGT-TANILQEADVPLLSNERCQQQMPEYNITENMI 955
Query: 201 CAG--GAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCNVRAPAVYTRVSKFSTWIN 258
CAG G SCQGDSGGPL+CQ+ N W L G+ S+G K P VY RVS+F+ WI
Sbjct: 956 CAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQ 1015
Query: 259 QVI 261
+
Sbjct: 1016 SFL 1018
>gi|110815798 ovochymase 1 [Homo sapiens]
Length = 1134
Score = 169 bits (428), Expect = 2e-42
Identities = 98/254 (38%), Positives = 138/254 (54%), Gaps = 14/254 (5%)
Query: 19 CGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAAHC-- 76
CGIP P S+RI GE A WPWQV L+ G + CGG++I+ W++TAAHC
Sbjct: 561 CGIPPFSPQW-LSRRIAGGEEACPHCWPWQVGLR-FLGDYQCGGAIINPVWILTAAHCVQ 618
Query: 77 -NVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNNDVTLLKLASPAQYTT 135
+P ++ G++DR+ QV I H +N+ + ++D+ L++L+SP +Y +
Sbjct: 619 LKNNPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNS 678
Query: 136 RISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQCRQYWGSS- 194
+ PVCL S E L C TGWG +S G + + LQQ+ + ++ C + S+
Sbjct: 679 VVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLA-SRLQQIQVHVLEREVCEHTYYSAH 737
Query: 195 ---ITDSMICAGGAGASS---CQGDSGGPLVCQKGN-TWVLIGIVSWGTKNCNVRAPAVY 247
IT+ MICAG A + CQGDSGGPLVC+ N +VL GIVSWG P V+
Sbjct: 738 PGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVF 797
Query: 248 TRVSKFSTWINQVI 261
RV F WI I
Sbjct: 798 ARVMIFLDWIQSKI 811
Score = 146 bits (368), Expect = 2e-35
Identities = 96/271 (35%), Positives = 144/271 (53%), Gaps = 32/271 (11%)
Query: 19 CGIPAI-----KPALS--FSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVV 71
CGI + +PA+ F RI + N+ + PWQVSL+ S HFCGGSLI + VV
Sbjct: 25 CGIRMVNMKSKEPAVGSRFFSRISSWRNSTVTGHPWQVSLK-SDEHHFCGGSLIQEDRVV 83
Query: 72 TAAHCNVSPGRH-----FVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTT-MNNDVTLL 125
TAAHC S V GEY + Q + VS+ ITHP +NS M+ D+ LL
Sbjct: 84 TAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSPDIALL 143
Query: 126 KLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVN 185
L ++ + P+CL S++ + G+ C+++GWG++S + LQ++ LP++
Sbjct: 144 YLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSGWGKISKTSEYSNV-LQEMELPIMDDR 202
Query: 186 QCRQYWGS----SITDSMICAG--GAGASSCQGDSGGPLVCQK-GNTWVLIGIVSW---- 234
C S + +M+CAG G +CQGDSGGPLVC++ G W+L GI SW
Sbjct: 203 ACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSWVAGC 262
Query: 235 -----GTKNCNVRAP-AVYTRVSKFSTWINQ 259
+N +V+A ++++VS+ +I Q
Sbjct: 263 AGGSVPVRNNHVKASLGIFSKVSELMDFITQ 293
>gi|33695155 hepsin [Homo sapiens]
Length = 417
Score = 167 bits (423), Expect = 9e-42
Identities = 102/247 (41%), Positives = 132/247 (53%), Gaps = 22/247 (8%)
Query: 33 RIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAAHC----NVSPGRHFVVLG 88
RIV G + LG WPWQVSL+ G H CGGSL+S WV+TAAHC N R V G
Sbjct: 162 RIVGGRDTSLGRWPWQVSLR-YDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAG 220
Query: 89 EYDRSSNAEPLQVLSVSRAITHPSW------NSTTMNNDVTLLKLASPAQYTTRISPVCL 142
++S LQ L V + H + NS +ND+ L+ L+SP T I PVCL
Sbjct: 221 AVAQAS-PHGLQ-LGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCL 278
Query: 143 ASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQCR--QYWGSSITDSMI 200
++ +AL +G C TGWG G LQ+ +P+++ + C ++G+ I M
Sbjct: 279 PAAGQALVDGKICTVTGWGNTQYYGQQAGV-LQEARVPIISNDVCNGADFYGNQIKPKMF 337
Query: 201 CAG--GAGASSCQGDSGGPLVCQ----KGNTWVLIGIVSWGTKNCNVRAPAVYTRVSKFS 254
CAG G +CQGDSGGP VC+ + W L GIVSWGT + P VYT+VS F
Sbjct: 338 CAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFR 397
Query: 255 TWINQVI 261
WI Q I
Sbjct: 398 EWIFQAI 404
>gi|4504481 hepsin [Homo sapiens]
Length = 417
Score = 167 bits (423), Expect = 9e-42
Identities = 102/247 (41%), Positives = 132/247 (53%), Gaps = 22/247 (8%)
Query: 33 RIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAAHC----NVSPGRHFVVLG 88
RIV G + LG WPWQVSL+ G H CGGSL+S WV+TAAHC N R V G
Sbjct: 162 RIVGGRDTSLGRWPWQVSLR-YDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAG 220
Query: 89 EYDRSSNAEPLQVLSVSRAITHPSW------NSTTMNNDVTLLKLASPAQYTTRISPVCL 142
++S LQ L V + H + NS +ND+ L+ L+SP T I PVCL
Sbjct: 221 AVAQAS-PHGLQ-LGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCL 278
Query: 143 ASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQCR--QYWGSSITDSMI 200
++ +AL +G C TGWG G LQ+ +P+++ + C ++G+ I M
Sbjct: 279 PAAGQALVDGKICTVTGWGNTQYYGQQAGV-LQEARVPIISNDVCNGADFYGNQIKPKMF 337
Query: 201 CAG--GAGASSCQGDSGGPLVCQ----KGNTWVLIGIVSWGTKNCNVRAPAVYTRVSKFS 254
CAG G +CQGDSGGP VC+ + W L GIVSWGT + P VYT+VS F
Sbjct: 338 CAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFR 397
Query: 255 TWINQVI 261
WI Q I
Sbjct: 398 EWIFQAI 404
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 165 bits (418), Expect = 3e-41
Identities = 93/235 (39%), Positives = 127/235 (54%), Gaps = 9/235 (3%)
Query: 31 SQRIVNGENAVLGSWPWQVSLQD--SSGFHFCGGSLISQSWVVTAAHC-NVSPGRHF--V 85
S RIV G N+ G WPWQVSLQ ++ H CGGSLI WV+TAAHC + P + +
Sbjct: 388 STRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI 447
Query: 86 VLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNNDVTLLKLASPAQYTTRISPVCLASS 145
G + S + + I H ++ + N+D+ L+KL +P YT P+CL S
Sbjct: 448 YSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507
Query: 146 NEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQC-RQYWGSSITDSMICAG- 203
+ T C TGWG G + LQ+V +PLVT +C ++Y IT M+CAG
Sbjct: 508 GDTSTIYTNCWVTGWGFSKEKGEIQNI-LQKVNIPLVTNEECQKRYQDYKITQRMVCAGY 566
Query: 204 -GAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCNVRAPAVYTRVSKFSTWI 257
G +C+GDSGGPLVC+ W L+GI SWG P VYT+V+++ WI
Sbjct: 567 KEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621
>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
Length = 2040
Score = 164 bits (416), Expect = 6e-41
Identities = 98/255 (38%), Positives = 130/255 (50%), Gaps = 21/255 (8%)
Query: 15 SSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAA 74
SS+ CG P ++P IV G A SWPWQVSL+ G HFCGG+LIS WV+TAA
Sbjct: 1802 SSFDCGKPQVEPK-KCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAA 1860
Query: 75 HC---NVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNNDVTLLKLASPA 131
HC + P + V+LG + + +Q + VSR P+ D+ LLKL+ PA
Sbjct: 1861 HCLKKSSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEPT------QADIALLKLSRPA 1914
Query: 132 QYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQCRQYW 191
T ++ P CL S + +T C TGWG G L++ L ++ C Y
Sbjct: 1915 VITDKVMPACLPSPDYMVTARTECYITGWGETQGTFGT--GLLKEAQLLVIENEVCNHY- 1971
Query: 192 GSSITDSMICAG--GAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCNVRAPAVYTR 249
ICA G SCQGDSGGPLVC + + ++L G+ SWG P VY R
Sbjct: 1972 ------KYICAEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYAR 2025
Query: 250 VSKFSTWINQVIAYN 264
VS+F TWI ++ N
Sbjct: 2026 VSRFVTWIEGMMRNN 2040
>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
sapiens]
Length = 529
Score = 162 bits (411), Expect = 2e-40
Identities = 93/236 (39%), Positives = 121/236 (51%), Gaps = 9/236 (3%)
Query: 29 SFSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAAHCNVSPGR---HFV 85
S RIV GE+A+ G+WPWQVSL + H CGGS+I+ W+VTAAHC P H+
Sbjct: 288 SRQSRIVGGESALPGAWPWQVSLHVQN-VHVCGGSIITPEWIVTAAHCVEKPLNNPWHWT 346
Query: 86 VLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNNDVTLLKLASPAQYTTRISPVCLASS 145
R S V + I+HP+++S T NND+ L+KL P + + PVCL +
Sbjct: 347 AFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNP 406
Query: 146 NEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQC--RQYWGSSITDSMICAG 203
L C +GWG G + L + L+ +C R + + IT +MICAG
Sbjct: 407 GMMLQPEQLCWISGWGATEEKGKTSEV-LNAAKVLLIETQRCNSRYVYDNLITPAMICAG 465
Query: 204 --GAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCNVRAPAVYTRVSKFSTWI 257
SCQGDSGGPLV K N W LIG SWG+ P VY V F+ WI
Sbjct: 466 FLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 521
>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
sapiens]
Length = 492
Score = 162 bits (411), Expect = 2e-40
Identities = 93/236 (39%), Positives = 121/236 (51%), Gaps = 9/236 (3%)
Query: 29 SFSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAAHCNVSPGR---HFV 85
S RIV GE+A+ G+WPWQVSL + H CGGS+I+ W+VTAAHC P H+
Sbjct: 251 SRQSRIVGGESALPGAWPWQVSLHVQN-VHVCGGSIITPEWIVTAAHCVEKPLNNPWHWT 309
Query: 86 VLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNNDVTLLKLASPAQYTTRISPVCLASS 145
R S V + I+HP+++S T NND+ L+KL P + + PVCL +
Sbjct: 310 AFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNP 369
Query: 146 NEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQC--RQYWGSSITDSMICAG 203
L C +GWG G + L + L+ +C R + + IT +MICAG
Sbjct: 370 GMMLQPEQLCWISGWGATEEKGKTSEV-LNAAKVLLIETQRCNSRYVYDNLITPAMICAG 428
Query: 204 --GAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCNVRAPAVYTRVSKFSTWI 257
SCQGDSGGPLV K N W LIG SWG+ P VY V F+ WI
Sbjct: 429 FLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 484
>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
Length = 275
Score = 162 bits (411), Expect = 2e-40
Identities = 98/272 (36%), Positives = 137/272 (50%), Gaps = 14/272 (5%)
Query: 3 LLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQ--DSSGFHFC 60
+L+L L + + +S PA AL IV G+ A WPWQVSL+ D HFC
Sbjct: 1 MLNLLLLALPVLASRAYAAPAPGQALQ-RVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFC 59
Query: 61 GGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPL-QVLSVSRAITHPSWNSTTMN 119
GGSLI WV+TAAHC + L R + Q+L VSR I HP + + +
Sbjct: 60 GGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIG 119
Query: 120 NDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAH-LQQVA 178
D+ LL+L P ++ + V L ++E G+ C TGWG + + P L+QV
Sbjct: 120 ADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVK 179
Query: 179 LPLVTVNQCRQ------YWGSSIT---DSMICAGGAGASSCQGDSGGPLVCQKGNTWVLI 229
+P++ + C Y G + D M+CAG SCQGDSGGPLVC+ TW+
Sbjct: 180 VPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQA 239
Query: 230 GIVSWGTKNCNVRAPAVYTRVSKFSTWINQVI 261
G+VSWG P +YTRV+ + WI+ +
Sbjct: 240 GVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYV 271
>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
Length = 275
Score = 161 bits (407), Expect = 6e-40
Identities = 97/272 (35%), Positives = 137/272 (50%), Gaps = 14/272 (5%)
Query: 3 LLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGF--HFC 60
+L+L L + + +S PA AL IV G+ A WPWQVSL+ + HFC
Sbjct: 1 MLNLLLLALPVLASRAYAAPAPGQALQ-RVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFC 59
Query: 61 GGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPL-QVLSVSRAITHPSWNSTTMN 119
GGSLI WV+TAAHC + L R + Q+L VSR I HP + + +
Sbjct: 60 GGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIG 119
Query: 120 NDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAH-LQQVA 178
D+ LL+L P ++ + V L ++E G+ C TGWG + + P L+QV
Sbjct: 120 ADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVK 179
Query: 179 LPLVTVNQCRQ------YWGSSIT---DSMICAGGAGASSCQGDSGGPLVCQKGNTWVLI 229
+P++ + C Y G + D M+CAG SCQGDSGGPLVC+ TW+
Sbjct: 180 VPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQA 239
Query: 230 GIVSWGTKNCNVRAPAVYTRVSKFSTWINQVI 261
G+VSWG P +YTRV+ + WI+ +
Sbjct: 240 GVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYV 271
>gi|13994276 marapsin [Homo sapiens]
Length = 290
Score = 161 bits (407), Expect = 6e-40
Identities = 96/275 (34%), Positives = 140/275 (50%), Gaps = 22/275 (8%)
Query: 2 LLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFCG 61
LLL L ++ CG P + R+V G++ G WPWQVS+Q +G HFCG
Sbjct: 9 LLLLLCFGSQRAKAATACGRPRML------NRMVGGQDTQEGEWPWQVSIQ-RNGSHFCG 61
Query: 62 GSLISQSWVVTAAHC--NVSPGRHF-VVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTM 118
GSLI++ WV+TAAHC N S + V+LG V + ++P + T
Sbjct: 62 GSLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTAS 121
Query: 119 NNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVT-PAHLQQV 177
+ DV L++L +P +T I PVCL + G+ C TGWG S + P LQ++
Sbjct: 122 SADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKL 181
Query: 178 ALPLVTVNQCRQ---------YWGSSITDSMICAG--GAGASSCQGDSGGPLVCQKGNTW 226
A+P++ +C Y +I + M+CAG +C+GDSGGPLVC G +W
Sbjct: 182 AVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSW 241
Query: 227 VLIGIVSWGTKNCNVRAPAVYTRVSKFSTWINQVI 261
+ G++SWG P VY RV+ WI+++I
Sbjct: 242 LQAGVISWGEGCARQNRPGVYIRVTAHHNWIHRII 276
>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 161 bits (407), Expect = 6e-40
Identities = 91/245 (37%), Positives = 129/245 (52%), Gaps = 10/245 (4%)
Query: 19 CGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAAHCN- 77
CG+ +PA + RIV G A G +PWQ SL+++ HFCG ++I+ W+V+AAHC
Sbjct: 191 CGL---QPAWRMAGRIVGGMEASPGEFPWQASLRENKE-HFCGAAIINARWLVSAAHCFN 246
Query: 78 --VSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNNDVTLLKLASPAQYTT 135
P + +G S + V + + HP +N+ T + DV +L+L SP +
Sbjct: 247 EFQDPTKWVAYVGATYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGR 306
Query: 136 RISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQCRQYWGSSI 195
I PVCL ++ C+ +GWG L V P LQ+ + L+ C +G S+
Sbjct: 307 HIQPVCLPAATHIFPPSKKCLISGWGYLKEDFLVKPEVLQKATVELLDQALCASLYGHSL 366
Query: 196 TDSMICAG--GAGASSCQGDSGGPLVCQK-GNTWVLIGIVSWGTKNCNVRAPAVYTRVSK 252
TD M+CAG SCQGDSGGPLVC++ + L GIVSWG R P VY RV++
Sbjct: 367 TDRMVCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYARVTR 426
Query: 253 FSTWI 257
WI
Sbjct: 427 LRDWI 431
Score = 155 bits (392), Expect = 3e-38
Identities = 88/265 (33%), Positives = 136/265 (51%), Gaps = 9/265 (3%)
Query: 3 LLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGG 62
L ++ L V + CG +PA+ R+V G A G PWQVSL++ S HFCG
Sbjct: 476 LSTVPLDWVTVPKLQECGA---RPAMEKPTRVVGGFGAASGEVPWQVSLKEGSR-HFCGA 531
Query: 63 SLISQSWVVTAAHC--NVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNN 120
+++ W+++AAHC + + LG + + R + HP +N ++
Sbjct: 532 TVVGDRWLLSAAHCFNHTKVEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDF 591
Query: 121 DVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALP 180
D+ +L+LASP + I PVCL + + G C+ +GWG P LQ+ ++
Sbjct: 592 DLAVLELASPLAFNKYIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVG 651
Query: 181 LVTVNQCRQYWGSSITDSMICAG--GAGASSCQGDSGGPLVCQKG-NTWVLIGIVSWGTK 237
++ C + S+TD MICAG SCQGDSGGPL C++ + L GIVSWG
Sbjct: 652 IIDQKTCSVLYNFSLTDRMICAGFLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIG 711
Query: 238 NCNVRAPAVYTRVSKFSTWINQVIA 262
V+ P VYTR+++ WI ++++
Sbjct: 712 CAQVKKPGVYTRITRLKGWILEIMS 736
Score = 154 bits (389), Expect = 8e-38
Identities = 91/235 (38%), Positives = 126/235 (53%), Gaps = 9/235 (3%)
Query: 33 RIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAAHC---NVSPGRHFVVLGE 89
RIV G A G WPWQVSL H CG L+++ W+++AAHC P + LG
Sbjct: 826 RIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDPKQWAAFLGT 885
Query: 90 YDRSSNAEPLQVLSVSRAITHPSWNSTTMNNDVTLLKLASPAQYTTRISPVCLASSNEAL 149
S AE Q+ V+R HP +N T++ DV LL+LA P + + + P+CL
Sbjct: 886 -PFLSGAEG-QLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPEPAPRP 943
Query: 150 TEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQCRQYWGSSITDSMICAG--GAGA 207
+G CV TGWG + G++ LQ+ A+ L++ CR+++ I+ M+CAG G
Sbjct: 944 PDGTRCVITGWGSVREGGSMA-RQLQKAAVRLLSEQTCRRFYPVQISSRMLCAGFPQGGV 1002
Query: 208 SSCQGDSGGPLVCQK-GNTWVLIGIVSWGTKNCNVRAPAVYTRVSKFSTWINQVI 261
SC GD+GGPL C++ WVL G+ SWG P VYTRV+ WI Q I
Sbjct: 1003 DSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWIGQHI 1057
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 160 bits (406), Expect = 8e-40
Identities = 93/234 (39%), Positives = 130/234 (55%), Gaps = 12/234 (5%)
Query: 33 RIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAAHCNVSPGRHFVVLGEYDR 92
+IV G N S P+QVSL +SG+HFCGGSLI++ WVV+A HC S R V LGE++
Sbjct: 23 KIVGGYNCEENSVPYQVSL--NSGYHFCGGSLINEQWVVSAGHCYKS--RIQVRLGEHNI 78
Query: 93 SSNAEPLQVLSVSRAITHPSWNSTTMNNDVTLLKLASPAQYTTRISPVCLASSNEALTEG 152
Q ++ ++ I HP ++ T+NND+ L+KL+S A R+S + L ++ A G
Sbjct: 79 EVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPA--TG 136
Query: 153 LTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQCRQYWGSSITDSMICAG--GAGASSC 210
C+ +GWG + G P LQ + P+++ +C + IT +M C G G SC
Sbjct: 137 TKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSC 196
Query: 211 QGDSGGPLVCQKGNTWVLIGIVSWGTKNCNVRAPAVYTRVSKFSTWINQVIAYN 264
QGDSGGP+VC L G+VSWG P VYT+V + WI IA N
Sbjct: 197 QGDSGGPVVC----NGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAAN 246
>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
Length = 304
Score = 159 bits (403), Expect = 2e-39
Identities = 101/269 (37%), Positives = 141/269 (52%), Gaps = 20/269 (7%)
Query: 6 LTLSLVLLGSSW-------GC-GIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGF 57
L L +L G +W GC + + +IV G S P+QVSL +SG
Sbjct: 45 LELHPLLGGRTWRAARDADGCEALGTVAVPFDDDDKIVGGYTCEENSLPYQVSL--NSGS 102
Query: 58 HFCGGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTT 117
HFCGGSLIS+ WVV+AAHC + R V LGE++ Q ++ ++ I HP +N T
Sbjct: 103 HFCGGSLISEQWVVSAAHCYKT--RIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDT 160
Query: 118 MNNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQV 177
++ND+ L+KL+SPA R+S + L ++ A G C+ +GWG G P L+ +
Sbjct: 161 LDNDIMLIKLSSPAVINARVSTISLPTAPPA--AGTECLISGWGNTLSFGADYPDELKCL 218
Query: 178 ALPLVTVNQCRQYWGSSITDSMICAG--GAGASSCQGDSGGPLVCQKGNTWVLIGIVSWG 235
P++T +C+ + IT+SM C G G SCQ DSGGP+VC L G+VSWG
Sbjct: 219 DAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVC----NGQLQGVVSWG 274
Query: 236 TKNCNVRAPAVYTRVSKFSTWINQVIAYN 264
P VYT+V + WI IA N
Sbjct: 275 HGCAWKNRPGVYTKVYNYVDWIKDTIAAN 303
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 159 bits (401), Expect = 3e-39
Identities = 94/234 (40%), Positives = 130/234 (55%), Gaps = 12/234 (5%)
Query: 33 RIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAAHCNVSPGRHFVVLGEYDR 92
+IV G S P+QVSL +SG HFCGGSLIS+ WVV+AAHC + R V LGE++
Sbjct: 23 KIVGGYTCEENSLPYQVSL--NSGSHFCGGSLISEQWVVSAAHCYKT--RIQVRLGEHNI 78
Query: 93 SSNAEPLQVLSVSRAITHPSWNSTTMNNDVTLLKLASPAQYTTRISPVCLASSNEALTEG 152
Q ++ ++ I HP +N T++ND+ L+KL+SPA R+S + L ++ A G
Sbjct: 79 KVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPA--AG 136
Query: 153 LTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQCRQYWGSSITDSMICAG--GAGASSC 210
C+ +GWG G P L+ + P++T +C+ + IT+SM C G G SC
Sbjct: 137 TECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSC 196
Query: 211 QGDSGGPLVCQKGNTWVLIGIVSWGTKNCNVRAPAVYTRVSKFSTWINQVIAYN 264
Q DSGGP+VC L G+VSWG P VYT+V + WI IA N
Sbjct: 197 QRDSGGPVVC----NGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTIAAN 246
>gi|29244926 corin [Homo sapiens]
Length = 1042
Score = 158 bits (399), Expect = 5e-39
Identities = 93/258 (36%), Positives = 134/258 (51%), Gaps = 14/258 (5%)
Query: 12 LLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVV 71
LL + CG +PA ++RI+ G + G WPWQ SLQ H CG LI++ WV+
Sbjct: 783 LLCTKQDCGR---RPAARMNKRILGGRTSRPGRWPWQCSLQSEPSGHICGCVLIAKKWVL 839
Query: 72 TAAHC---NVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNNDVTLLKLA 128
T AHC + VVLG + + +Q V I HP ++ ++ D+++++L+
Sbjct: 840 TVAHCFEGRENAAVWKVVLGINNLDHPSVFMQTRFVKTIILHPRYSRAVVDYDISIVELS 899
Query: 129 SPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQCR 188
T + PVCL + + L C TGWG + GN P LQ+ + ++++ C+
Sbjct: 900 EDISETGYVRPVCLPNPEQWLEPDTYCYITGWGHM---GNKMPFKLQEGEVRIISLEHCQ 956
Query: 189 QYWG-SSITDSMICAG--GAGASSCQGDSGGPLVCQK-GNTWVLIGIVSWGTK-NCNVRA 243
Y+ +IT MICAG SC GDSGGPLVC+K G W L G+ SWG+ V
Sbjct: 957 SYFDMKTITTRMICAGYESGTVDSCMGDSGGPLVCEKPGGRWTLFGLTSWGSVCFSKVLG 1016
Query: 244 PAVYTRVSKFSTWINQVI 261
P VY+ VS F WI + I
Sbjct: 1017 PGVYSNVSYFVEWIKRQI 1034
>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
Length = 321
Score = 158 bits (399), Expect = 5e-39
Identities = 103/271 (38%), Positives = 141/271 (52%), Gaps = 19/271 (7%)
Query: 1 MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFC 60
+LLL + L GCG P + A RIV G A G+WPWQ SL+ H C
Sbjct: 8 LLLLLAVPGVSLRTLQPGCGRPQVSDA---GGRIVGGHAAPAGAWPWQASLR-LRRVHVC 63
Query: 61 GGSLISQSWVVTAAHC---NVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITH--PSWNS 115
GGSL+S WV+TAAHC +++ + V LGE + + + +V + I H PS
Sbjct: 64 GGSLLSPQWVLTAAHCFSGSLNSSDYQVHLGELEITLSPH---FSTVRQIILHSSPSGQP 120
Query: 116 TTMNNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRL-SGVGNVTPAHL 174
T + D+ L++L+ P ++RI PVCL +++ G+ C TGWG G P L
Sbjct: 121 GT-SGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSL 179
Query: 175 QQVALPLVTVNQCRQYW----GSSITDSMICAGGAGASSCQGDSGGPLVCQKGNTWVLIG 230
++V + +V CR+ + GS + M+CA G G +CQ DSGGPLVCQ WV G
Sbjct: 180 REVKVSVVDTETCRRDYPGPGGSILQPDMLCARGPG-DACQDDSGGPLVCQVNGAWVQAG 238
Query: 231 IVSWGTKNCNVRAPAVYTRVSKFSTWINQVI 261
IVSWG P VYTRV + WI + I
Sbjct: 239 IVSWGEGCGRPNRPGVYTRVPAYVNWIRRHI 269
>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
Length = 247
Score = 157 bits (397), Expect = 9e-39
Identities = 95/244 (38%), Positives = 133/244 (54%), Gaps = 12/244 (4%)
Query: 23 AIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAAHCNVSPGR 82
A+ +IV G S P+QVSL +SG+HFCGGSLIS+ WVV+A HC S R
Sbjct: 13 AVAAPFDDDDKIVGGYICEENSVPYQVSL--NSGYHFCGGSLISEQWVVSAGHCYKS--R 68
Query: 83 HFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNNDVTLLKLASPAQYTTRISPVCL 142
V LGE++ Q ++ ++ I HP +NS T++ND+ L+KL+SPA +R+S + L
Sbjct: 69 IQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISL 128
Query: 143 ASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQCRQYWGSSITDSMICA 202
++ A G + +GWG G P LQ + P+++ +C + IT++M C
Sbjct: 129 PTAPPA--AGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCV 186
Query: 203 G--GAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCNVRAPAVYTRVSKFSTWINQV 260
G G SCQGDSGGP+V + L GIVSWG P VYT+V + WI
Sbjct: 187 GFLEGGKDSCQGDSGGPVV----SNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIKDT 242
Query: 261 IAYN 264
IA N
Sbjct: 243 IAAN 246
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.131 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,555,546
Number of Sequences: 37866
Number of extensions: 454740
Number of successful extensions: 1805
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 165
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1066
Number of HSP's gapped (non-prelim): 192
length of query: 264
length of database: 18,247,518
effective HSP length: 100
effective length of query: 164
effective length of database: 14,460,918
effective search space: 2371590552
effective search space used: 2371590552
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.