Guide to the Human Genome
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Search of human proteins with 4502313

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502313 ATPase, H+ transporting, lysosomal, V0 subunit c
[Homo sapiens]
         (155 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502313 ATPase, H+ transporting, lysosomal, V0 subunit c [Hom...   289   8e-79
gi|86792634 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit...    92   1e-19
gi|4757816 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit ...    92   1e-19
gi|85794840 ATP synthase, H+ transporting, mitochondrial F0 comp...    34   0.058
gi|4502301 ATP synthase, H+ transporting, mitochondrial F0 compl...    34   0.058
gi|50659074 ATP synthase, H+ transporting, mitochondrial F0 comp...    34   0.058
gi|50593533 ATP synthase, H+ transporting, mitochondrial F0 comp...    34   0.058
gi|50659069 ATP synthase, H+ transporting, mitochondrial F0 comp...    33   0.13 
gi|4885081 ATP synthase, H+ transporting, mitochondrial F0 compl...    33   0.13 
gi|38679890 solute carrier organic anion transporter family, mem...    31   0.49 
gi|6912372 forkhead box D3 [Homo sapiens]                              30   0.83 
gi|7706113 protocadherin 12 precursor [Homo sapiens]                   30   0.83 
gi|21735483 transient receptor potential cation channel, subfami...    28   3.2  
gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]         28   4.1  
gi|4506431 RAS p21 protein activator 1 isoform 1 [Homo sapiens]        28   4.1  
gi|22749211 transmembrane and tetratricopeptide repeat containin...    28   4.1  
gi|24497504 forkhead box A2 isoform 2 [Homo sapiens]                   27   7.0  
gi|211063479 major facilitator superfamily domain containing 2 i...    27   7.0  
gi|42713696 major facilitator superfamily domain containing 2 is...    27   7.0  
gi|194394143 forkhead box A2 isoform 1 [Homo sapiens]                  27   7.0  

>gi|4502313 ATPase, H+ transporting, lysosomal, V0 subunit c [Homo
           sapiens]
          Length = 155

 Score =  289 bits (739), Expect = 8e-79
 Identities = 155/155 (100%), Positives = 155/155 (100%)

Query: 1   MSESKSGPEYASFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEQIMKSIIPVV 60
           MSESKSGPEYASFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEQIMKSIIPVV
Sbjct: 1   MSESKSGPEYASFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEQIMKSIIPVV 60

Query: 61  MAGIIAIYGLVVAVLIANSLNDDISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRG 120
           MAGIIAIYGLVVAVLIANSLNDDISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRG
Sbjct: 61  MAGIIAIYGLVVAVLIANSLNDDISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRG 120

Query: 121 TAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 155
           TAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
Sbjct: 121 TAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK 155


>gi|86792634 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
           isoform 2 [Homo sapiens]
          Length = 158

 Score = 92.4 bits (228), Expect = 1e-19
 Identities = 49/149 (32%), Positives = 85/149 (57%), Gaps = 10/149 (6%)

Query: 17  MGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEQIMKSIIPVVMAGIIAIYGLVVAVLI 76
           +G   A+  S +GAA+G   +G+ I    V  P    K+++ ++    +AIYG+++A++I
Sbjct: 5   LGIGLAISLSVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVI 64

Query: 77  AN-----SLNDDISL-----YKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPR 126
           +N     S  D  ++     +  +   GAGL+VGLS L  G  +GIVG       AQ P 
Sbjct: 65  SNMAEPFSATDPKAIGHRNYHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALADAQNPS 124

Query: 127 LFVGMILILIFAEVLGLYGLIVALILSTK 155
           LFV ++++ IF   +GL+G+IVA++ +++
Sbjct: 125 LFVKILIVEIFGSAIGLFGVIVAILQTSR 153



 Score = 31.6 bits (70), Expect = 0.29
 Identities = 16/66 (24%), Positives = 30/66 (45%)

Query: 10  YASFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEQIMKSIIPVVMAGIIAIYG 69
           Y + +++ GA   +  S L         G+G A      P   +K +I  +    I ++G
Sbjct: 84  YHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFGSAIGLFG 143

Query: 70  LVVAVL 75
           ++VA+L
Sbjct: 144 VIVAIL 149


>gi|4757816 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
           isoform 1 [Homo sapiens]
          Length = 205

 Score = 92.4 bits (228), Expect = 1e-19
 Identities = 49/149 (32%), Positives = 85/149 (57%), Gaps = 10/149 (6%)

Query: 17  MGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEQIMKSIIPVVMAGIIAIYGLVVAVLI 76
           +G   A+  S +GAA+G   +G+ I    V  P    K+++ ++    +AIYG+++A++I
Sbjct: 52  LGIGLAISLSVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVI 111

Query: 77  AN-----SLNDDISL-----YKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPR 126
           +N     S  D  ++     +  +   GAGL+VGLS L  G  +GIVG       AQ P 
Sbjct: 112 SNMAEPFSATDPKAIGHRNYHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALADAQNPS 171

Query: 127 LFVGMILILIFAEVLGLYGLIVALILSTK 155
           LFV ++++ IF   +GL+G+IVA++ +++
Sbjct: 172 LFVKILIVEIFGSAIGLFGVIVAILQTSR 200



 Score = 31.6 bits (70), Expect = 0.29
 Identities = 16/66 (24%), Positives = 30/66 (45%)

Query: 10  YASFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEQIMKSIIPVVMAGIIAIYG 69
           Y + +++ GA   +  S L         G+G A      P   +K +I  +    I ++G
Sbjct: 131 YHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFGSAIGLFG 190

Query: 70  LVVAVL 75
           ++VA+L
Sbjct: 191 VIVAIL 196


>gi|85794840 ATP synthase, H+ transporting, mitochondrial F0
           complex, subunit C2 isoform b precursor [Homo sapiens]
          Length = 198

 Score = 33.9 bits (76), Expect = 0.058
 Identities = 26/79 (32%), Positives = 44/79 (55%), Gaps = 7/79 (8%)

Query: 78  NSLNDDISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQP----RLFVGMIL 133
           ++++ DI     F+  GA  +VG++G  AG  IG V  + + G A+ P    +LF   IL
Sbjct: 119 SAISRDIDTAAKFIGAGAA-TVGVAGSGAG--IGTVFGSLIIGYARNPSLKQQLFSYAIL 175

Query: 134 ILIFAEVLGLYGLIVALIL 152
               +E +GL+ L+VA ++
Sbjct: 176 GFALSEAMGLFCLMVAFLI 194


>gi|4502301 ATP synthase, H+ transporting, mitochondrial F0 complex,
           subunit C3 precursor [Homo sapiens]
          Length = 142

 Score = 33.9 bits (76), Expect = 0.058
 Identities = 26/79 (32%), Positives = 44/79 (55%), Gaps = 7/79 (8%)

Query: 78  NSLNDDISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQP----RLFVGMIL 133
           ++++ DI     F+  GA  +VG++G  AG  IG V  + + G A+ P    +LF   IL
Sbjct: 63  SAISRDIDTAAKFIGAGAA-TVGVAGSGAG--IGTVFGSLIIGYARNPSLKQQLFSYAIL 119

Query: 134 ILIFAEVLGLYGLIVALIL 152
               +E +GL+ L+VA ++
Sbjct: 120 GFALSEAMGLFCLMVAFLI 138


>gi|50659074 ATP synthase, H+ transporting, mitochondrial F0
           complex, subunit C3 precursor [Homo sapiens]
          Length = 142

 Score = 33.9 bits (76), Expect = 0.058
 Identities = 26/79 (32%), Positives = 44/79 (55%), Gaps = 7/79 (8%)

Query: 78  NSLNDDISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQP----RLFVGMIL 133
           ++++ DI     F+  GA  +VG++G  AG  IG V  + + G A+ P    +LF   IL
Sbjct: 63  SAISRDIDTAAKFIGAGAA-TVGVAGSGAG--IGTVFGSLIIGYARNPSLKQQLFSYAIL 119

Query: 134 ILIFAEVLGLYGLIVALIL 152
               +E +GL+ L+VA ++
Sbjct: 120 GFALSEAMGLFCLMVAFLI 138


>gi|50593533 ATP synthase, H+ transporting, mitochondrial F0
           complex, subunit C2 isoform a precursor [Homo sapiens]
          Length = 157

 Score = 33.9 bits (76), Expect = 0.058
 Identities = 26/79 (32%), Positives = 44/79 (55%), Gaps = 7/79 (8%)

Query: 78  NSLNDDISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQP----RLFVGMIL 133
           ++++ DI     F+  GA  +VG++G  AG  IG V  + + G A+ P    +LF   IL
Sbjct: 78  SAISRDIDTAAKFIGAGAA-TVGVAGSGAG--IGTVFGSLIIGYARNPSLKQQLFSYAIL 134

Query: 134 ILIFAEVLGLYGLIVALIL 152
               +E +GL+ L+VA ++
Sbjct: 135 GFALSEAMGLFCLMVAFLI 153


>gi|50659069 ATP synthase, H+ transporting, mitochondrial F0
           complex, subunit C1 precursor [Homo sapiens]
          Length = 136

 Score = 32.7 bits (73), Expect = 0.13
 Identities = 26/74 (35%), Positives = 40/74 (54%), Gaps = 7/74 (9%)

Query: 83  DISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQP----RLFVGMILILIFA 138
           DI     F+  GA  +VG++G  AG  IG V  + + G A+ P    +LF   IL    +
Sbjct: 62  DIDTAAKFIGAGAA-TVGVAGSGAG--IGTVFGSLIIGYARNPSLKQQLFSYAILGFALS 118

Query: 139 EVLGLYGLIVALIL 152
           E +GL+ L+VA ++
Sbjct: 119 EAMGLFCLMVAFLI 132


>gi|4885081 ATP synthase, H+ transporting, mitochondrial F0 complex,
           subunit C1 precursor [Homo sapiens]
          Length = 136

 Score = 32.7 bits (73), Expect = 0.13
 Identities = 26/74 (35%), Positives = 40/74 (54%), Gaps = 7/74 (9%)

Query: 83  DISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQP----RLFVGMILILIFA 138
           DI     F+  GA  +VG++G  AG  IG V  + + G A+ P    +LF   IL    +
Sbjct: 62  DIDTAAKFIGAGAA-TVGVAGSGAG--IGTVFGSLIIGYARNPSLKQQLFSYAILGFALS 118

Query: 139 EVLGLYGLIVALIL 152
           E +GL+ L+VA ++
Sbjct: 119 EAMGLFCLMVAFLI 132


>gi|38679890 solute carrier organic anion transporter family, member
           4C1 [Homo sapiens]
          Length = 724

 Score = 30.8 bits (68), Expect = 0.49
 Identities = 28/114 (24%), Positives = 48/114 (42%), Gaps = 10/114 (8%)

Query: 8   PEYASFFAVMGASAAMVFSALGAAYGTAKSG--------TGIAAMSVMRPEQIMKSIIPV 59
           P + +F A M    A+VFS      G  K G        T   + S       + + + V
Sbjct: 172 PRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLFEDTCVTTRNSTSCTSSTSSLSNYLYV 231

Query: 60  VMAG--IIAIYGLVVAVLIANSLNDDISLYKSFLQLGAGLSVGLSGLAAGFAIG 111
            + G  ++   G  +  L    L+D +  +KS L +G G ++ + G A G+ +G
Sbjct: 232 FILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAMSILGPAIGYVLG 285


>gi|6912372 forkhead box D3 [Homo sapiens]
          Length = 478

 Score = 30.0 bits (66), Expect = 0.83
 Identities = 36/126 (28%), Positives = 51/126 (40%), Gaps = 21/126 (16%)

Query: 2   SESKSGPEYASFFAVMGASAAMVFSALGA--AYGTAKSGTGIAAMSVMRPEQIMKSIIPV 59
           SE  + P ++    + G  AA   SA+GA  A GT  SG G  A S +RP   ++S    
Sbjct: 370 SEPSARPSFSIENIIGGGPAAPGGSAVGAGVAGGTGGSGGGSTAQSFLRPPGTVQS---- 425

Query: 60  VMAGIIAIYGLVVAVLIANSLNDDISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVR 119
                        A L+A   +  +SL ++   +   LSV LSG     A      A   
Sbjct: 426 -------------AALMAT--HQPLSLSRTTATIAPILSVPLSGQFLQPAASAAAAAAAA 470

Query: 120 GTAQQP 125
             A+ P
Sbjct: 471 AQAKWP 476


>gi|7706113 protocadherin 12 precursor [Homo sapiens]
          Length = 1184

 Score = 30.0 bits (66), Expect = 0.83
 Identities = 14/37 (37%), Positives = 27/37 (72%), Gaps = 1/37 (2%)

Query: 118 VRGTAQQP-RLFVGMILILIFAEVLGLYGLIVALILS 153
           +R +A++P  L + M+ ++  A +LG++GLI+AL +S
Sbjct: 702 LRDSARKPGALSMSMLTVICLAVLLGIFGLILALFMS 738


>gi|21735483 transient receptor potential cation channel, subfamily
           V, member 3 [Homo sapiens]
          Length = 790

 Score = 28.1 bits (61), Expect = 3.2
 Identities = 27/114 (23%), Positives = 54/114 (47%), Gaps = 13/114 (11%)

Query: 45  SVMRPEQIMKSIIPVVMAGIIAI--YGLVVAVLIANSLND--DISLYKSFLQLGAGLSVG 100
           SVM  + I+  ++  +   I+ +  +G+ +A LI     D  D S Y SF    +   + 
Sbjct: 576 SVMIQKVILHDVLKFLFVYIVFLLGFGVALASLIEKCPKDNKDCSSYGSF----SDAVLE 631

Query: 101 LSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILST 154
           L  L  G     +GD  ++  ++ P LF+ +++  +    + L  +++AL+  T
Sbjct: 632 LFKLTIG-----LGDLNIQQNSKYPILFLFLLITYVILTFVLLLNMLIALMGET 680


>gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]
          Length = 237

 Score = 27.7 bits (60), Expect = 4.1
 Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 6/84 (7%)

Query: 70  LVVAVLIANSLNDDISLYKSFLQLGAGLSVGLSGL-AAGFAIGIVGDAGVRGTAQQPR-- 126
           L++A+ I   +++D         +G+   V +  L A G  I I+G  G  G  ++ R  
Sbjct: 25  LILALAIWVRVSNDSQAIFGSEDVGSSSYVAVDILIAVGAIIMILGFLGCCGAIKESRCM 84

Query: 127 ---LFVGMILILIFAEVLGLYGLI 147
               F+G++LIL+     G+ G +
Sbjct: 85  LLLFFIGLLLILLLQVATGILGAV 108


>gi|4506431 RAS p21 protein activator 1 isoform 1 [Homo sapiens]
          Length = 1047

 Score = 27.7 bits (60), Expect = 4.1
 Identities = 24/87 (27%), Positives = 35/87 (40%), Gaps = 13/87 (14%)

Query: 34  TAKSGTGIAAMSVMRPEQIMKSIIPVVMAGIIAIYGLVVAVLIANSLNDDISLYKSFLQL 93
           TA +G G AA        + +  IP  +    A Y  +V   +A +L             
Sbjct: 15  TAGAGGGGAAAGSSAYPAVCRVKIPAALPVAAAPYPGLVETGVAGTL------------- 61

Query: 94  GAGLSVGLSGLAAGFAIGIVGDAGVRG 120
           G G ++G   L AG   G +G AG+ G
Sbjct: 62  GGGAALGSEFLGAGSVAGALGGAGLTG 88


>gi|22749211 transmembrane and tetratricopeptide repeat containing 2
           [Homo sapiens]
          Length = 836

 Score = 27.7 bits (60), Expect = 4.1
 Identities = 18/64 (28%), Positives = 34/64 (53%), Gaps = 1/64 (1%)

Query: 40  GIAAMSVMRPEQIMKSIIPVVMAGIIAIYGLVVAVLIANSLNDDISLYKSFLQLGAGLSV 99
           G  A+ V   ++ +KS+I    A +I  YGL  A+   +  N+++ LY+S +++    + 
Sbjct: 438 GARALYVKVQKRFLKSLIFYATATLIVFYGLKTAIRNGDWQNEEM-LYRSGIKVNPAKAW 496

Query: 100 GLSG 103
           G  G
Sbjct: 497 GNLG 500


>gi|24497504 forkhead box A2 isoform 2 [Homo sapiens]
          Length = 457

 Score = 26.9 bits (58), Expect = 7.0
 Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 2/64 (3%)

Query: 61  MAGIIAIYGLVVAVLIANSLNDDISLYKSFLQLGAGLSVGLSGLA--AGFAIGIVGDAGV 118
           M G+     +  A + + S N           +GAG+S  L+G++  AG   G+ G AG 
Sbjct: 37  MNGMNTYMSMSAAAMGSGSGNMSAGSMNMSSYVGAGMSPSLAGMSPGAGAMAGMGGSAGA 96

Query: 119 RGTA 122
            G A
Sbjct: 97  AGVA 100


>gi|211063479 major facilitator superfamily domain containing 2
           isoform 1 [Homo sapiens]
          Length = 543

 Score = 26.9 bits (58), Expect = 7.0
 Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 6/65 (9%)

Query: 85  SLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRL-FVGMILILIFAEVLGL 143
           S Y  F +  +G+S+G+S L+  FA         RG +Q  R+ F   +L+ +   VL L
Sbjct: 442 SFYVFFTKFASGVSLGISTLSLDFA-----GYQTRGCSQPERVKFTLNMLVTMAPIVLIL 496

Query: 144 YGLIV 148
            GL++
Sbjct: 497 LGLLL 501


>gi|42713696 major facilitator superfamily domain containing 2
           isoform 2 [Homo sapiens]
          Length = 530

 Score = 26.9 bits (58), Expect = 7.0
 Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 6/65 (9%)

Query: 85  SLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRL-FVGMILILIFAEVLGL 143
           S Y  F +  +G+S+G+S L+  FA         RG +Q  R+ F   +L+ +   VL L
Sbjct: 429 SFYVFFTKFASGVSLGISTLSLDFA-----GYQTRGCSQPERVKFTLNMLVTMAPIVLIL 483

Query: 144 YGLIV 148
            GL++
Sbjct: 484 LGLLL 488


>gi|194394143 forkhead box A2 isoform 1 [Homo sapiens]
          Length = 463

 Score = 26.9 bits (58), Expect = 7.0
 Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 2/64 (3%)

Query: 61  MAGIIAIYGLVVAVLIANSLNDDISLYKSFLQLGAGLSVGLSGLA--AGFAIGIVGDAGV 118
           M G+     +  A + + S N           +GAG+S  L+G++  AG   G+ G AG 
Sbjct: 43  MNGMNTYMSMSAAAMGSGSGNMSAGSMNMSSYVGAGMSPSLAGMSPGAGAMAGMGGSAGA 102

Query: 119 RGTA 122
            G A
Sbjct: 103 AGVA 106


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.139    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,254,796
Number of Sequences: 37866
Number of extensions: 142352
Number of successful extensions: 479
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 464
Number of HSP's gapped (non-prelim): 23
length of query: 155
length of database: 18,247,518
effective HSP length: 93
effective length of query: 62
effective length of database: 14,725,980
effective search space: 913010760
effective search space used: 913010760
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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