Guide to the Human Genome
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Search of human proteins with 4502271

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo
sapiens]
         (1020 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]  2026   0.0  
gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]  1789   0.0  
gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]            1786   0.0  
gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi...  1782   0.0  
gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi...  1768   0.0  
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi...  1632   0.0  
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]  1321   0.0  
gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]   1320   0.0  
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...   377   e-104
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...   377   e-104
gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom...   377   e-104
gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom...   377   e-104
gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom...   377   e-104
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom...   377   e-104
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom...   377   e-104
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap...   375   e-104
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap...   375   e-104
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap...   375   e-104
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap...   375   e-104
gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H...   370   e-102
gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [...   370   e-102
gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ...   361   2e-99
gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [...   360   3e-99
gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [...   360   4e-99
gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ...   341   2e-93
gi|49249977 Na+/K+ -ATPase alpha 4 subunit isoform 2 [Homo sapiens]   289   8e-78
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap...   258   2e-68
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa...   232   2e-60
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa...   232   2e-60
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa...   225   2e-58

>gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]
          Length = 1020

 Score = 2026 bits (5249), Expect = 0.0
 Identities = 1020/1020 (100%), Positives = 1020/1020 (100%)

Query: 1    MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKG 60
            MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKG
Sbjct: 1    MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKG 60

Query: 61   LTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAME 120
            LTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAME
Sbjct: 61   LTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAME 120

Query: 121  DEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINA 180
            DEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINA
Sbjct: 121  DEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINA 180

Query: 181  EEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNI 240
            EEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNI
Sbjct: 181  EEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNI 240

Query: 241  CFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFL 300
            CFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFL
Sbjct: 241  CFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFL 300

Query: 301  GVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLE 360
            GVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLE
Sbjct: 301  GVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLE 360

Query: 361  AVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALS 420
            AVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALS
Sbjct: 361  AVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALS 420

Query: 421  RIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPF 480
            RIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPF
Sbjct: 421  RIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPF 480

Query: 481  NSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYM 540
            NSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYM
Sbjct: 481  NSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYM 540

Query: 541  ELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAV 600
            ELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAV
Sbjct: 541  ELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAV 600

Query: 601  GKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKAC 660
            GKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKAC
Sbjct: 601  GKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKAC 660

Query: 661  VVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSP 720
            VVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSP
Sbjct: 661  VVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSP 720

Query: 721  ALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSN 780
            ALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSN
Sbjct: 721  ALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSN 780

Query: 781  IPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDK 840
            IPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDK
Sbjct: 781  IPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDK 840

Query: 841  LVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYG 900
            LVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYG
Sbjct: 841  LVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYG 900

Query: 901  QEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETA 960
            QEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETA
Sbjct: 901  QEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETA 960

Query: 961  LAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 1020
            LAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY
Sbjct: 961  LAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 1020


>gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]
          Length = 1023

 Score = 1789 bits (4634), Expect = 0.0
 Identities = 888/1023 (86%), Positives = 960/1023 (93%), Gaps = 3/1023 (0%)

Query: 1    MGRGAGRE-YSPAATTAENGG-GKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLS 58
            MG+G GR+ Y PAA + +    GKK +K++++DELKKEV+MDDHKLSLDEL RKY  DLS
Sbjct: 1    MGKGVGRDKYEPAAVSEQGDKKGKKGKKDRDMDELKKEVSMDDHKLSLDELHRKYGTDLS 60

Query: 59   KGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAA 118
            +GLT+ RA ++LARDGPNALTPPPTTPEW+KFCRQLFGGFS+LLWIGAILCFLAY IQAA
Sbjct: 61   RGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSMLLWIGAILCFLAYSIQAA 120

Query: 119  MEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQI 178
             E+EP NDNLYLGVVL+AVVI+TGCFSYYQEAKSSKIM+SFKNMVPQQALVIR GEKM I
Sbjct: 121  TEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSI 180

Query: 179  NAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETR 238
            NAEEVVVGDLVEVKGGDR+PADLRIIS++GCKVDNSSLTGESEPQTRSP+FT+ENPLETR
Sbjct: 181  NAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETR 240

Query: 239  NICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAV 298
            NI FFSTNCVEGTARGIV+ TGDRTVMGRIATLASGLE G+TPIA EIEHFI +ITGVAV
Sbjct: 241  NIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAV 300

Query: 299  FLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKN 358
            FLGVSFF+LSLIL Y+WLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKN
Sbjct: 301  FLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKN 360

Query: 359  LEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTA 418
            LEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTE+QSG +FDK S TW A
Sbjct: 361  LEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLA 420

Query: 419  LSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEI 478
            LSRIAGLCNRAVF+A QEN+ + KR  AGDASESALLKCIEL CGSV++MR+R  K+ EI
Sbjct: 421  LSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIVEI 480

Query: 479  PFNSTNKYQLSIHEREDSPQ-SHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQN 537
            PFNSTNKYQLSIH+  ++ +  H+LVMKGAPERILDRCS+IL+ GKE PLD+E++DAFQN
Sbjct: 481  PFNSTNKYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQN 540

Query: 538  AYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVP 597
            AY+ELGGLGERVLGFC L LP  +FP GF+FDTD++NFP + LCFVGL+SMIDPPRAAVP
Sbjct: 541  AYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVP 600

Query: 598  DAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREA 657
            DAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIP+SQVNPR+A
Sbjct: 601  DAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDA 660

Query: 658  KACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVN 717
            KACVVHGSDLKDMTSEQLD+ILK HTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVN
Sbjct: 661  KACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVN 720

Query: 718  DSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTL 777
            DSPALKKADIG+AMGI+GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTL
Sbjct: 721  DSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTL 780

Query: 778  TSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQ 837
            TSNIPEITPFL+FIIANIPLPLGTVTILCIDLGTDMVPAISLAYE AESDIMKRQPRN +
Sbjct: 781  TSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPK 840

Query: 838  TDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLED 897
            TDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLP  LLG+R+DWDDR +ND+ED
Sbjct: 841  TDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPIHLLGLRVDWDDRWINDVED 900

Query: 898  SYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLE 957
            SYGQ+WTYEQRK+VEFTCHTAFF SIVVVQWADL+ICKTRRNSVFQQGMKNKILIFGL E
Sbjct: 901  SYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFE 960

Query: 958  ETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKE 1017
            ETALAAFLSYCPGMGVALRMYPLK TWWFCAFPYSLLIF+YDEVRKLI+RR PGGWVEKE
Sbjct: 961  ETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKE 1020

Query: 1018 TYY 1020
            TYY
Sbjct: 1021 TYY 1023


>gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]
          Length = 1013

 Score = 1786 bits (4625), Expect = 0.0
 Identities = 885/1001 (88%), Positives = 949/1001 (94%), Gaps = 2/1001 (0%)

Query: 22   KKKQKEK-ELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTP 80
            K K KE+ +LD+LKKEVAM +HK+S++E+ RKY  D  +GLT+ +AQ++LARDGPNALTP
Sbjct: 13   KNKGKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTP 72

Query: 81   PPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIV 140
            PPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQA  ED+PS DNLYLG+VLAAVVI+
Sbjct: 73   PPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVII 132

Query: 141  TGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPAD 200
            TGCFSYYQEAKSSKIM+SFKNMVPQQALVIREGEKMQ+NAEEVVVGDLVE+KGGDRVPAD
Sbjct: 133  TGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPAD 192

Query: 201  LRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATG 260
            LRIIS+HGCKVDNSSLTGESEPQTRSP+ TH+NPLETRNI FFSTNCVEGTARG+V+ATG
Sbjct: 193  LRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATG 252

Query: 261  DRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVI 320
            DRTVMGRIATLASGLEVG+TPIA+EIEHFIQLITGVAVFLGVSFF+LSLILGY+WLEAVI
Sbjct: 253  DRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVI 312

Query: 321  FLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLT 380
            FLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLT
Sbjct: 313  FLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLT 372

Query: 381  QNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISV 440
            QNRMTVAHMWFDNQIHEADTTEDQSG +FDK S TW ALS IAGLCNRAVFK GQ+NI V
Sbjct: 373  QNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPV 432

Query: 441  SKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHERED-SPQS 499
             KRD AGDASESALLKCIELS GSV+ MR+RN KVAEIPFNSTNKYQLSIHE ED +   
Sbjct: 433  LKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQLSIHETEDPNDNR 492

Query: 500  HVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPS 559
            ++LVMKGAPERILDRCSTIL+QGKE PLD+EM++AFQNAY+ELGGLGERVLGFC   LP 
Sbjct: 493  YLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPE 552

Query: 560  GKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPI 619
             +FP+GF FD D++NF T+ LCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPI
Sbjct: 553  EQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPI 612

Query: 620  TAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEIL 679
            TAKAIAKGVGIISEGNETVEDIAARLNIP+SQVNPR+AKACV+HG+DLKD TSEQ+DEIL
Sbjct: 613  TAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEIL 672

Query: 680  KNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVS 739
            +NHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIG+AMGI+GSDVS
Sbjct: 673  QNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVS 732

Query: 740  KQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPL 799
            KQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFI+ANIPLPL
Sbjct: 733  KQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPL 792

Query: 800  GTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQA 859
            GT+TILCIDLGTDMVPAISLAYEAAESDIMKRQPRN +TDKLVNERLISMAYGQIGMIQA
Sbjct: 793  GTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQA 852

Query: 860  LGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAF 919
            LGGFF+YFVILAENGFLP  L+GIRL+WDDRT+NDLEDSYGQ+WTYEQRKVVEFTCHTAF
Sbjct: 853  LGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEFTCHTAF 912

Query: 920  FASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYP 979
            F SIVVVQWADLIICKTRRNSVFQQGMKNKILIFGL EETALAAFLSYCPGM VALRMYP
Sbjct: 913  FVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYP 972

Query: 980  LKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 1020
            LK +WWFCAFPYS LIF+YDE+RKLILRR PGGWVEKETYY
Sbjct: 973  LKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY 1013


>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapiens]
          Length = 1023

 Score = 1782 bits (4615), Expect = 0.0
 Identities = 883/1015 (86%), Positives = 954/1015 (93%), Gaps = 2/1015 (0%)

Query: 8    EYSPAATTAENGG-GKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRA 66
            +Y PAA + +    GKK +K++++DELKKEV+MDDHKLSLDEL RKY  DLS+GLT+ RA
Sbjct: 9    KYEPAAVSEQGDKKGKKGKKDRDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARA 68

Query: 67   QDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSND 126
             ++LARDGPNALTPPPTTPEW+KFCRQLFGGFS+LLWIGAILCFLAY IQAA E+EP ND
Sbjct: 69   AEILARDGPNALTPPPTTPEWIKFCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQND 128

Query: 127  NLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVG 186
            NLYLGVVL+AVVI+TGCFSYYQEAKSSKIM+SFKNMVPQQALVIR GEKM INAEEVVVG
Sbjct: 129  NLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVG 188

Query: 187  DLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTN 246
            DLVEVKGGDR+PADLRIIS++GCKVDNSSLTGESEPQTRSP+FT+ENPLETRNI FFSTN
Sbjct: 189  DLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTN 248

Query: 247  CVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFV 306
            CVEGTARGIV+ TGDRTVMGRIATLASGLE G+TPIA EIEHFI +ITGVAVFLGVSFF+
Sbjct: 249  CVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFI 308

Query: 307  LSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLG 366
            LSLIL Y+WLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLG
Sbjct: 309  LSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLG 368

Query: 367  STSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLC 426
            STSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTE+QSG +FDK S TW ALSRIAGLC
Sbjct: 369  STSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLC 428

Query: 427  NRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKY 486
            NRAVF+A QEN+ + KR  AGDASESALLKCIEL CGSV++MR+R  K+ EIPFNSTNKY
Sbjct: 429  NRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKY 488

Query: 487  QLSIHEREDSPQ-SHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGL 545
            QLSIH+  ++ +  H+LVMKGAPERILDRCS+IL+ GKE PLD+E++DAFQNAY+ELGGL
Sbjct: 489  QLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGL 548

Query: 546  GERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRS 605
            GERVLGFC L LP  +FP GF+FDTD++NFP + LCFVGL+SMIDPPRAAVPDAVGKCRS
Sbjct: 549  GERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRS 608

Query: 606  AGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGS 665
            AGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIP+SQVNPR+AKACVVHGS
Sbjct: 609  AGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGS 668

Query: 666  DLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKA 725
            DLKDMTSEQLD+ILK HTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKA
Sbjct: 669  DLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKA 728

Query: 726  DIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEIT 785
            DIG+AMGI+GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEIT
Sbjct: 729  DIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEIT 788

Query: 786  PFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNER 845
            PFL+FIIANIPLPLGTVTILCIDLGTDMVPAISLAYE AESDIMKRQPRN +TDKLVNER
Sbjct: 789  PFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNER 848

Query: 846  LISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTY 905
            LISMAYGQIGMIQALGGFFTYFVILAENGFLP  LLG+R+DWDDR +ND+EDSYGQ+WTY
Sbjct: 849  LISMAYGQIGMIQALGGFFTYFVILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTY 908

Query: 906  EQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFL 965
            EQRK+VEFTCHTAFF SIVVVQWADL+ICKTRRNSVFQQGMKNKILIFGL EETALAAFL
Sbjct: 909  EQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFL 968

Query: 966  SYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 1020
            SYCPGMGVALRMYPLK TWWFCAFPYSLLIF+YDEVRKLI+RR PGGWVEKETYY
Sbjct: 969  SYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 1023


>gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapiens]
          Length = 992

 Score = 1768 bits (4579), Expect = 0.0
 Identities = 875/992 (88%), Positives = 939/992 (94%), Gaps = 1/992 (0%)

Query: 30   LDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVK 89
            +DELKKEV+MDDHKLSLDEL RKY  DLS+GLT+ RA ++LARDGPNALTPPPTTPEW+K
Sbjct: 1    MDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIK 60

Query: 90   FCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQE 149
            FCRQLFGGFS+LLWIGAILCFLAY IQAA E+EP NDNLYLGVVL+AVVI+TGCFSYYQE
Sbjct: 61   FCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQE 120

Query: 150  AKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGC 209
            AKSSKIM+SFKNMVPQQALVIR GEKM INAEEVVVGDLVEVKGGDR+PADLRIIS++GC
Sbjct: 121  AKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGC 180

Query: 210  KVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIA 269
            KVDNSSLTGESEPQTRSP+FT+ENPLETRNI FFSTNCVEGTARGIV+ TGDRTVMGRIA
Sbjct: 181  KVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIA 240

Query: 270  TLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVAN 329
            TLASGLE G+TPIA EIEHFI +ITGVAVFLGVSFF+LSLIL Y+WLEAVIFLIGIIVAN
Sbjct: 241  TLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVAN 300

Query: 330  VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 389
            VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM
Sbjct: 301  VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 360

Query: 390  WFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDA 449
            WFDNQIHEADTTE+QSG +FDK S TW ALSRIAGLCNRAVF+A QEN+ + KR  AGDA
Sbjct: 361  WFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDA 420

Query: 450  SESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQ-SHVLVMKGAP 508
            SESALLKCIEL CGSV++MR+R  K+ EIPFNSTNKYQLSIH+  ++ +  H+LVMKGAP
Sbjct: 421  SESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAP 480

Query: 509  ERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKF 568
            ERILDRCS+IL+ GKE PLD+E++DAFQNAY+ELGGLGERVLGFC L LP  +FP GF+F
Sbjct: 481  ERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQF 540

Query: 569  DTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV 628
            DTD++NFP + LCFVGL+SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV
Sbjct: 541  DTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV 600

Query: 629  GIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFA 688
            GIISEGNETVEDIAARLNIP+SQVNPR+AKACVVHGSDLKDMTSEQLD+ILK HTEIVFA
Sbjct: 601  GIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFA 660

Query: 689  RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILL 748
            RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIG+AMGI+GSDVSKQAADMILL
Sbjct: 661  RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 720

Query: 749  DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCID 808
            DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFL+FIIANIPLPLGTVTILCID
Sbjct: 721  DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCID 780

Query: 809  LGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFV 868
            LGTDMVPAISLAYE AESDIMKRQPRN +TDKLVNERLISMAYGQIGMIQALGGFFTYFV
Sbjct: 781  LGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFV 840

Query: 869  ILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQW 928
            ILAENGFLP  LLG+R+DWDDR +ND+EDSYGQ+WTYEQRK+VEFTCHTAFF SIVVVQW
Sbjct: 841  ILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQW 900

Query: 929  ADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCA 988
            ADL+ICKTRRNSVFQQGMKNKILIFGL EETALAAFLSYCPGMGVALRMYPLK TWWFCA
Sbjct: 901  ADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCA 960

Query: 989  FPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 1020
            FPYSLLIF+YDEVRKLI+RR PGGWVEKETYY
Sbjct: 961  FPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 992


>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapiens]
          Length = 1029

 Score = 1632 bits (4225), Expect = 0.0
 Identities = 804/999 (80%), Positives = 902/999 (90%), Gaps = 1/999 (0%)

Query: 22   KKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPP 81
            K++++++ ++ELKKEV MDDHKL+L+EL  KY VDL+KG ++QRA+++L R GPN +TPP
Sbjct: 32   KREKQKRNMEELKKEVVMDDHKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPP 91

Query: 82   PTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVT 141
            PTTPEWVKFC+QLFGGFS+LLW GAILCF+AY IQ    +EP+ DNLYL +VL+ VVIVT
Sbjct: 92   PTTPEWVKFCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVT 151

Query: 142  GCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADL 201
            GCFSYYQEAKSSKIM+SFKNMVPQQALVIR GEKMQIN +EVV+GDLVE+KGGDRVPADL
Sbjct: 152  GCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADL 211

Query: 202  RIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGD 261
            R+IS+ GCKVDNSSLTGESEPQ+RSP+FTHENPLETRNICFFSTNCVEGTARGIVIATGD
Sbjct: 212  RLISAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVEGTARGIVIATGD 271

Query: 262  RTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIF 321
             TVMGRIA+L SGL VG+TPIA EIEHFI LIT VAVFLGV+FF LSL+LGY WLEA+IF
Sbjct: 272  STVMGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAIIF 331

Query: 322  LIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQ 381
            LIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQ
Sbjct: 332  LIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQ 391

Query: 382  NRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVS 441
            NRMTVAHMWFD  ++EADTTE+Q+G TF K S TW  L+RIAGLCNRA FKA QE + ++
Sbjct: 392  NRMTVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEILPIA 451

Query: 442  KRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHV 501
            KR T GDASESALLK IE S  SV +MR++NPKVAEIPFNSTNKYQ+SIH REDS Q+HV
Sbjct: 452  KRATTGDASESALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQMSIHLREDSSQTHV 511

Query: 502  LVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGK 561
            L+MKGAPERIL+ CST L+ G+E  ++ EM++AFQNAY+ELGGLGERVLGFC LNLPS  
Sbjct: 512  LMMKGAPERILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNLPS-S 570

Query: 562  FPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITA 621
            F +GF F+TDE+NFP + LCFVGL+SMIDPPRAAVPDAV KCRSAGIKVIMVTGDHPITA
Sbjct: 571  FSKGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITA 630

Query: 622  KAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKN 681
            KAIAKGVGIISEG ET E++AARL IP+S+V+   AKA VVHG++LKD+ S+QLD+IL+N
Sbjct: 631  KAIAKGVGIISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQN 690

Query: 682  HTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQ 741
            H EIVFARTSPQQKLIIVEGCQR GA+VAVTGDGVNDSPALKKADIGIAMGISGSDVSKQ
Sbjct: 691  HPEIVFARTSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQ 750

Query: 742  AADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGT 801
            AADMILLDDNFASIVTGVEEGRLIFDNLKKSI YTLTSNIPEITPFL+FII  IPLPLGT
Sbjct: 751  AADMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGT 810

Query: 802  VTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALG 861
            +TILCIDLGTDMVPAISLAYE+AESDIMKR PRN +TD LVN RLI MAYGQIGMIQAL 
Sbjct: 811  ITILCIDLGTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALA 870

Query: 862  GFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFA 921
            GFFTYFVILAENGF P  LLGIRL W+D+ +NDLEDSYGQ+WTYEQRKVVEFTC TAFF 
Sbjct: 871  GFFTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFV 930

Query: 922  SIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLK 981
            +IVVVQWADLII KTRRNS+FQQGM+NK+LIFG+LEET LAAFLSY PGM VALRMYPLK
Sbjct: 931  TIVVVQWADLIISKTRRNSLFQQGMRNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLK 990

Query: 982  VTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 1020
            +TWW CA PYS+LIF+YDE+RKL++R++P GWVE+ETYY
Sbjct: 991  ITWWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY 1029


>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
          Length = 1039

 Score = 1321 bits (3420), Expect = 0.0
 Identities = 659/1017 (64%), Positives = 809/1017 (79%), Gaps = 13/1017 (1%)

Query: 17   ENGGGKKK-----------QKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQR 65
            + G GK+K           +K+   +E +KE+ +DDHKLS  EL  KY  D+  GL++ R
Sbjct: 23   DKGDGKEKYRGLKNNCLELKKKNHKEEFQKELHLDDHKLSNRELEEKYGTDIIMGLSSTR 82

Query: 66   AQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSN 125
            A ++LARDGPN+LTPP  TPE VKF +Q+ GGFSILLW+GA LC++AYGIQ + +   S 
Sbjct: 83   AAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILLWVGAFLCWIAYGIQYSSDKSASL 142

Query: 126  DNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVV 185
            +N+YLG VL  VVI+TG F+YYQEAKS+ IM SF  M+PQQALVIR+ EK  I +E++VV
Sbjct: 143  NNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVV 202

Query: 186  GDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFST 245
            GD+VEVKGGD++PAD+R++SS GC+VDNSSLTGESEPQ RS EFTHENPLET+NICF+ST
Sbjct: 203  GDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFYST 262

Query: 246  NCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFF 305
             C+EGT  G+VI TGDRT++G IA+LASG+   +TPIA+EIEHF+ ++ GVAV +G+ FF
Sbjct: 263  TCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEHFVHIVAGVAVSIGILFF 322

Query: 306  VLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETL 365
            ++++ L Y  L+++IFLIGIIVANVPEGLLATVTV L+LTAKRMA+KNCLVKNLEAVETL
Sbjct: 323  IIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETL 382

Query: 366  GSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGL 425
            GSTS ICSDKTGTLTQNRMTVAH+WFDNQI  ADT+ED S   FD+ S TW +LS+I  L
Sbjct: 383  GSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWASLSKIITL 442

Query: 426  CNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNK 485
            CNRA FK GQEN+ + K+   GDASE+ALLK  E+  G V ++R RN KVAEIPFNSTNK
Sbjct: 443  CNRAEFKPGQENVPIMKKAVIGDASETALLKFSEVILGDVMEIRKRNRKVAEIPFNSTNK 502

Query: 486  YQLSIHEREDSP-QSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGG 544
            +QLSIHE +D   +  ++VMKGAPERIL++CSTI++ G+E PLDK     F  AYMELGG
Sbjct: 503  FQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMINGEEHPLDKSTAKTFHTAYMELGG 562

Query: 545  LGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCR 604
            LGERVLGFC L LP+ +FP  + FD D +NFPT  LCFVGL+SMIDPPR+ VPDAV KCR
Sbjct: 563  LGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCR 622

Query: 605  SAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHG 664
            SAGIKVIMVTGDHPITAKAIAK VGIIS  +ETVEDIA RLNI + QVN R+AKA VV G
Sbjct: 623  SAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAKAAVVTG 682

Query: 665  SDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKK 724
             +LKDM+SEQLDEIL N+ EIVFARTSPQQKLIIVEGCQRQ A+VAVTGDGVNDSPALKK
Sbjct: 683  MELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKK 742

Query: 725  ADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEI 784
            ADIGIAMGI+GSD +K AADM+LLDDNFASIVTGVEEGRLIFDNLKK+IAY+LT NI E+
Sbjct: 743  ADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIAEL 802

Query: 785  TPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNE 844
             PFL++II  +PLP+GT+TIL IDLGTD++P+I+LAYE AESDIM R+PR+   D+LVN+
Sbjct: 803  CPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQ 862

Query: 845  RLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWT 904
             L   +Y  IG++QALG F  YF + A+ GFLP  L+ +R++W+   +NDL+DSYGQEWT
Sbjct: 863  PLAVYSYLHIGLMQALGAFLVYFTVYAQEGFLPRTLINLRVEWEKDYVNDLKDSYGQEWT 922

Query: 905  YEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGM-KNKILIFGLLEETALAA 963
              QR+ +E+T +TAFF  I+V Q ADLII KTRRNS+FQQG+ +NK++  G+  +  +  
Sbjct: 923  RYQREYLEWTGYTAFFVGILVQQIADLIIRKTRRNSIFQQGLFRNKVIWVGITSQIIIGL 982

Query: 964  FLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 1020
             LSY  G   AL    L+  +WF A P+++LI++YDEVRKL +R YPG W +K  YY
Sbjct: 983  ILSYGLGSVTALSFTMLRAQYWFVAVPHAILIWVYDEVRKLFIRLYPGSWWDKNMYY 1039


>gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]
          Length = 1035

 Score = 1320 bits (3417), Expect = 0.0
 Identities = 640/1022 (62%), Positives = 809/1022 (79%), Gaps = 2/1022 (0%)

Query: 1    MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKG 60
            +G G G + +   +  +  GG   +++++L+ +KKE+ ++DH+LS+ EL +KYQ   +KG
Sbjct: 14   LGPGPGGDMAAKMSKKKKAGGGGGKRKEKLENMKKEMEINDHQLSVAELEQKYQTSATKG 73

Query: 61   LTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAME 120
            L+   A ++L RDGPNAL PP  TPE+VKF RQL GG   L+W+ A +C +A+ IQA+  
Sbjct: 74   LSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICLIAFAIQASEG 133

Query: 121  DEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINA 180
            D  ++DNLYL + L AVV+VTGCF YYQE KS+ I+ SFKN+VPQQA VIR+G+K QINA
Sbjct: 134  DLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINA 193

Query: 181  EEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNI 240
            +++VVGDLVE+KGGDRVPAD+RI+++ GCKVDNSSLTGESEPQTRSPE THE+PLETRNI
Sbjct: 194  DQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNI 253

Query: 241  CFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFL 300
             FFST C+EGT +G+V+ TGDRT++GRIA+LASG+E  +TPIA+EIEHF+ +I G+A+  
Sbjct: 254  AFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIEHFVDIIAGLAILF 313

Query: 301  GVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLE 360
            G +FF++++ +GY++L A++F + I+VA VPEGLLATVTVCL+LTAKR+A KNC+VKNLE
Sbjct: 314  GATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLE 373

Query: 361  AVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALS 420
            AVETLGSTS ICSDKTGTLTQNRMTV+H+WFDN IH ADTTEDQSG TFD+ S TW AL 
Sbjct: 374  AVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALC 433

Query: 421  RIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPF 480
            R+  LCNRA FK+GQ+ + V KR   GDASE+ALLK  EL+ G+    RDR PKV EIPF
Sbjct: 434  RVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPF 493

Query: 481  NSTNKYQLSIHERED-SPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAY 539
            NSTNK+QLSIH  ED     H+LVMKGAPER+L+RCS+IL++G+E+PLD++ ++AFQ AY
Sbjct: 494  NSTNKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPLDEQWREAFQTAY 553

Query: 540  MELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDA 599
            + LGGLGERVLGFCQL L    +P G+ FD + +NFP+  LCF GL+SMIDPPRA VPDA
Sbjct: 554  LSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDA 613

Query: 600  VGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKA 659
            V KCR+AGI+VIMVTGDHPITAKAIA  VGIISEG+ETVEDIAARL +P+ QVN ++A+A
Sbjct: 614  VLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVPVDQVNRKDARA 673

Query: 660  CVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDS 719
            CV++G  LKDM   +L E L+ H E+VFARTSPQQKL+IVE CQR GAIVAVTGDGVNDS
Sbjct: 674  CVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAIVAVTGDGVNDS 733

Query: 720  PALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTS 779
            PALKKADIG+AMGI+GSD +K AADMILLDDNFASIVTGVE+GRLIFDNLKKSIAYTLT 
Sbjct: 734  PALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTK 793

Query: 780  NIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTD 839
            NIPE+TP+L++I  ++PLPLG +TIL I+L TD+ P++SLAYE AESDIM  +PRN + D
Sbjct: 794  NIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRPRNPKRD 853

Query: 840  KLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSY 899
            +LVNE L + +Y QIG IQ+  GF  YF  +A+ G+ P   +G+R  W+D  + DL+DSY
Sbjct: 854  RLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQWEDHHLQDLQDSY 913

Query: 900  GQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQG-MKNKILIFGLLEE 958
            GQEWT+ QR   ++TC+T FF SI V Q AD++I KTRR S FQQG  +NKIL+  ++ +
Sbjct: 914  GQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGFFRNKILVIAIVFQ 973

Query: 959  TALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKET 1018
              +  FL YCPGM       P++  WW    PY +LIF+YDE+RKL +R  PG W ++E 
Sbjct: 974  VCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLGVRCCPGSWWDQEL 1033

Query: 1019 YY 1020
            YY
Sbjct: 1034 YY 1035


>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
            sapiens]
          Length = 1029

 Score =  377 bits (968), Expect = e-104
 Identities = 307/1034 (29%), Positives = 483/1034 (46%), Gaps = 103/1034 (9%)

Query: 42   HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 101
            H L   ++ R + V    GL+  +      R GPN L        W     Q       +
Sbjct: 5    HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64

Query: 102  LWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKN 161
            L + A++ F+    +   E E +       +V+  +++       +QE  +   +++ K 
Sbjct: 65   LLLAALVSFVLAWFE---EGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121

Query: 162  MVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRIIS--SHGCKVDNSSLT 217
              P+   VIR   K   +I A ++V GD+VEV  GD+VPADLR+I   S   +VD S LT
Sbjct: 122  YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181

Query: 218  GESEPQTRSPEFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASG 274
            GES   T+  E   +      + +N+ F  TN   G A G+ +ATG  T +G+I +  + 
Sbjct: 182  GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241

Query: 275  LEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IG 324
            +E  RTP+  +++ F + ++     + V+ +V+++        G SWL   ++     + 
Sbjct: 242  VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301

Query: 325  IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 384
            + VA +PEGL A +T CL L  +RMARKN +V++L +VETLG TS ICSDKTGTLT N+M
Sbjct: 302  LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361

Query: 385  TVAHMWFDNQ-------IHE---ADTTEDQSGATFDKRSPT----WTALSRIAGLCNRAV 430
            +V  M+   +       +HE   + TT    G       P     +  L  +A +C    
Sbjct: 362  SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421

Query: 431  FKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRN 472
              A   N +    +  G+A+E+AL   +E                   +C +V K   R 
Sbjct: 422  DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRK 481

Query: 473  PKVAEIPFNSTNKYQLSIHEREDSP----QSHVLVMKGAPERILDRCSTILVQGKEIPLD 528
                E    S ++  +S++     P    Q   + +KGAPE +++RCS++ V  +  PL 
Sbjct: 482  EFTLEF---SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLT 538

Query: 529  KEMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLM 586
               ++       + G   +  R L     + P  K        +  + + T+ L FVG +
Sbjct: 539  PTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETD-LTFVGCV 597

Query: 587  SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLN 646
             M+DPPR  V   + +C  AGI+V+M+TGD+  TA AI + +GI  +     ED+A +  
Sbjct: 598  GMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVAGK-- 651

Query: 647  IPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQG 706
                             G +  D++ EQ  +  +  T   FAR  P  K  IVE  Q   
Sbjct: 652  --------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHKSRIVENLQSFN 695

Query: 707  AIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIF 766
             I A+TGDGVND+PALKKA+IGIAMG SG+ V+K AA+M+L DDNFASIV  VEEGR I+
Sbjct: 696  EITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIY 754

Query: 767  DNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAES 826
             N+K+ I Y ++SN+ E+    L  I  +P  L  V +L ++L TD +PA +L +   + 
Sbjct: 755  SNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDL 814

Query: 827  DIMKRQPRNSQTDKLVNERLI--SMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIR 884
            DIM++ PR S  + L++  L    +A G    +  +     +FV  AE   +    L   
Sbjct: 815  DIMEKLPR-SPREALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNF 873

Query: 885  LDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQ 944
            L   +   N L      E  +E R        T   + +V ++  + +   +   S+ + 
Sbjct: 874  LKCSED--NPLFAGIDCE-VFESRFPT-----TMALSVLVTIEMCNALNSVSENQSLLRM 925

Query: 945  -GMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRK 1003
                N  L+  +    AL   +   P + +  ++ PL    W      SL + + DE  K
Sbjct: 926  PPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVILLDEALK 985

Query: 1004 LILRR------YPG 1011
             + R       YPG
Sbjct: 986  YLSRNHMHACLYPG 999


>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
            sapiens]
          Length = 1029

 Score =  377 bits (968), Expect = e-104
 Identities = 307/1034 (29%), Positives = 483/1034 (46%), Gaps = 103/1034 (9%)

Query: 42   HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 101
            H L   ++ R + V    GL+  +      R GPN L        W     Q       +
Sbjct: 5    HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64

Query: 102  LWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKN 161
            L + A++ F+    +   E E +       +V+  +++       +QE  +   +++ K 
Sbjct: 65   LLLAALVSFVLAWFE---EGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121

Query: 162  MVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRIIS--SHGCKVDNSSLT 217
              P+   VIR   K   +I A ++V GD+VEV  GD+VPADLR+I   S   +VD S LT
Sbjct: 122  YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181

Query: 218  GESEPQTRSPEFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASG 274
            GES   T+  E   +      + +N+ F  TN   G A G+ +ATG  T +G+I +  + 
Sbjct: 182  GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241

Query: 275  LEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IG 324
            +E  RTP+  +++ F + ++     + V+ +V+++        G SWL   ++     + 
Sbjct: 242  VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301

Query: 325  IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 384
            + VA +PEGL A +T CL L  +RMARKN +V++L +VETLG TS ICSDKTGTLT N+M
Sbjct: 302  LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361

Query: 385  TVAHMWFDNQ-------IHE---ADTTEDQSGATFDKRSPT----WTALSRIAGLCNRAV 430
            +V  M+   +       +HE   + TT    G       P     +  L  +A +C    
Sbjct: 362  SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421

Query: 431  FKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRN 472
              A   N +    +  G+A+E+AL   +E                   +C +V K   R 
Sbjct: 422  DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRK 481

Query: 473  PKVAEIPFNSTNKYQLSIHEREDSP----QSHVLVMKGAPERILDRCSTILVQGKEIPLD 528
                E    S ++  +S++     P    Q   + +KGAPE +++RCS++ V  +  PL 
Sbjct: 482  EFTLEF---SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLT 538

Query: 529  KEMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLM 586
               ++       + G   +  R L     + P  K        +  + + T+ L FVG +
Sbjct: 539  PTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETD-LTFVGCV 597

Query: 587  SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLN 646
             M+DPPR  V   + +C  AGI+V+M+TGD+  TA AI + +GI  +     ED+A +  
Sbjct: 598  GMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVAGK-- 651

Query: 647  IPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQG 706
                             G +  D++ EQ  +  +  T   FAR  P  K  IVE  Q   
Sbjct: 652  --------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHKSRIVENLQSFN 695

Query: 707  AIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIF 766
             I A+TGDGVND+PALKKA+IGIAMG SG+ V+K AA+M+L DDNFASIV  VEEGR I+
Sbjct: 696  EITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIY 754

Query: 767  DNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAES 826
             N+K+ I Y ++SN+ E+    L  I  +P  L  V +L ++L TD +PA +L +   + 
Sbjct: 755  SNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDL 814

Query: 827  DIMKRQPRNSQTDKLVNERLI--SMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIR 884
            DIM++ PR S  + L++  L    +A G    +  +     +FV  AE   +    L   
Sbjct: 815  DIMEKLPR-SPREALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNF 873

Query: 885  LDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQ 944
            L   +   N L      E  +E R        T   + +V ++  + +   +   S+ + 
Sbjct: 874  LKCSED--NPLFAGIDCE-VFESRFPT-----TMALSVLVTIEMCNALNSVSENQSLLRM 925

Query: 945  -GMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRK 1003
                N  L+  +    AL   +   P + +  ++ PL    W      SL + + DE  K
Sbjct: 926  PPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVILLDEALK 985

Query: 1004 LILRR------YPG 1011
             + R       YPG
Sbjct: 986  YLSRNHMHACLYPG 999


>gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo
            sapiens]
          Length = 1043

 Score =  377 bits (968), Expect = e-104
 Identities = 307/1034 (29%), Positives = 483/1034 (46%), Gaps = 103/1034 (9%)

Query: 42   HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 101
            H L   ++ R + V    GL+  +      R GPN L        W     Q       +
Sbjct: 5    HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64

Query: 102  LWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKN 161
            L + A++ F+    +   E E +       +V+  +++       +QE  +   +++ K 
Sbjct: 65   LLLAALVSFVLAWFE---EGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121

Query: 162  MVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRIIS--SHGCKVDNSSLT 217
              P+   VIR   K   +I A ++V GD+VEV  GD+VPADLR+I   S   +VD S LT
Sbjct: 122  YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181

Query: 218  GESEPQTRSPEFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASG 274
            GES   T+  E   +      + +N+ F  TN   G A G+ +ATG  T +G+I +  + 
Sbjct: 182  GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241

Query: 275  LEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IG 324
            +E  RTP+  +++ F + ++     + V+ +V+++        G SWL   ++     + 
Sbjct: 242  VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301

Query: 325  IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 384
            + VA +PEGL A +T CL L  +RMARKN +V++L +VETLG TS ICSDKTGTLT N+M
Sbjct: 302  LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361

Query: 385  TVAHMWFDNQ-------IHE---ADTTEDQSGATFDKRSPT----WTALSRIAGLCNRAV 430
            +V  M+   +       +HE   + TT    G       P     +  L  +A +C    
Sbjct: 362  SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421

Query: 431  FKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRN 472
              A   N +    +  G+A+E+AL   +E                   +C +V K   R 
Sbjct: 422  DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRK 481

Query: 473  PKVAEIPFNSTNKYQLSIHEREDSP----QSHVLVMKGAPERILDRCSTILVQGKEIPLD 528
                E    S ++  +S++     P    Q   + +KGAPE +++RCS++ V  +  PL 
Sbjct: 482  EFTLEF---SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLT 538

Query: 529  KEMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLM 586
               ++       + G   +  R L     + P  K        +  + + T+ L FVG +
Sbjct: 539  PTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETD-LTFVGCV 597

Query: 587  SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLN 646
             M+DPPR  V   + +C  AGI+V+M+TGD+  TA AI + +GI  +     ED+A +  
Sbjct: 598  GMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVAGK-- 651

Query: 647  IPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQG 706
                             G +  D++ EQ  +  +  T   FAR  P  K  IVE  Q   
Sbjct: 652  --------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHKSRIVENLQSFN 695

Query: 707  AIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIF 766
             I A+TGDGVND+PALKKA+IGIAMG SG+ V+K AA+M+L DDNFASIV  VEEGR I+
Sbjct: 696  EITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIY 754

Query: 767  DNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAES 826
             N+K+ I Y ++SN+ E+    L  I  +P  L  V +L ++L TD +PA +L +   + 
Sbjct: 755  SNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDL 814

Query: 827  DIMKRQPRNSQTDKLVNERLI--SMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIR 884
            DIM++ PR S  + L++  L    +A G    +  +     +FV  AE   +    L   
Sbjct: 815  DIMEKLPR-SPREALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNF 873

Query: 885  LDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQ 944
            L   +   N L      E  +E R        T   + +V ++  + +   +   S+ + 
Sbjct: 874  LKCSED--NPLFAGIDCE-VFESRFPT-----TMALSVLVTIEMCNALNSVSENQSLLRM 925

Query: 945  -GMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRK 1003
                N  L+  +    AL   +   P + +  ++ PL    W      SL + + DE  K
Sbjct: 926  PPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVILLDEALK 985

Query: 1004 LILRR------YPG 1011
             + R       YPG
Sbjct: 986  YLSRNHMHACLYPG 999


>gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo
            sapiens]
          Length = 1044

 Score =  377 bits (968), Expect = e-104
 Identities = 307/1034 (29%), Positives = 483/1034 (46%), Gaps = 103/1034 (9%)

Query: 42   HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 101
            H L   ++ R + V    GL+  +      R GPN L        W     Q       +
Sbjct: 5    HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64

Query: 102  LWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKN 161
            L + A++ F+    +   E E +       +V+  +++       +QE  +   +++ K 
Sbjct: 65   LLLAALVSFVLAWFE---EGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121

Query: 162  MVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRIIS--SHGCKVDNSSLT 217
              P+   VIR   K   +I A ++V GD+VEV  GD+VPADLR+I   S   +VD S LT
Sbjct: 122  YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181

Query: 218  GESEPQTRSPEFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASG 274
            GES   T+  E   +      + +N+ F  TN   G A G+ +ATG  T +G+I +  + 
Sbjct: 182  GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241

Query: 275  LEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IG 324
            +E  RTP+  +++ F + ++     + V+ +V+++        G SWL   ++     + 
Sbjct: 242  VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301

Query: 325  IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 384
            + VA +PEGL A +T CL L  +RMARKN +V++L +VETLG TS ICSDKTGTLT N+M
Sbjct: 302  LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361

Query: 385  TVAHMWFDNQ-------IHE---ADTTEDQSGATFDKRSPT----WTALSRIAGLCNRAV 430
            +V  M+   +       +HE   + TT    G       P     +  L  +A +C    
Sbjct: 362  SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421

Query: 431  FKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRN 472
              A   N +    +  G+A+E+AL   +E                   +C +V K   R 
Sbjct: 422  DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRK 481

Query: 473  PKVAEIPFNSTNKYQLSIHEREDSP----QSHVLVMKGAPERILDRCSTILVQGKEIPLD 528
                E    S ++  +S++     P    Q   + +KGAPE +++RCS++ V  +  PL 
Sbjct: 482  EFTLEF---SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLT 538

Query: 529  KEMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLM 586
               ++       + G   +  R L     + P  K        +  + + T+ L FVG +
Sbjct: 539  PTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETD-LTFVGCV 597

Query: 587  SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLN 646
             M+DPPR  V   + +C  AGI+V+M+TGD+  TA AI + +GI  +     ED+A +  
Sbjct: 598  GMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVAGK-- 651

Query: 647  IPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQG 706
                             G +  D++ EQ  +  +  T   FAR  P  K  IVE  Q   
Sbjct: 652  --------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHKSRIVENLQSFN 695

Query: 707  AIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIF 766
             I A+TGDGVND+PALKKA+IGIAMG SG+ V+K AA+M+L DDNFASIV  VEEGR I+
Sbjct: 696  EITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIY 754

Query: 767  DNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAES 826
             N+K+ I Y ++SN+ E+    L  I  +P  L  V +L ++L TD +PA +L +   + 
Sbjct: 755  SNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDL 814

Query: 827  DIMKRQPRNSQTDKLVNERLI--SMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIR 884
            DIM++ PR S  + L++  L    +A G    +  +     +FV  AE   +    L   
Sbjct: 815  DIMEKLPR-SPREALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNF 873

Query: 885  LDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQ 944
            L   +   N L      E  +E R        T   + +V ++  + +   +   S+ + 
Sbjct: 874  LKCSED--NPLFAGIDCE-VFESRFPT-----TMALSVLVTIEMCNALNSVSENQSLLRM 925

Query: 945  -GMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRK 1003
                N  L+  +    AL   +   P + +  ++ PL    W      SL + + DE  K
Sbjct: 926  PPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVILLDEALK 985

Query: 1004 LILRR------YPG 1011
             + R       YPG
Sbjct: 986  YLSRNHMHACLYPG 999


>gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo
            sapiens]
          Length = 1052

 Score =  377 bits (968), Expect = e-104
 Identities = 307/1034 (29%), Positives = 483/1034 (46%), Gaps = 103/1034 (9%)

Query: 42   HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 101
            H L   ++ R + V    GL+  +      R GPN L        W     Q       +
Sbjct: 5    HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64

Query: 102  LWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKN 161
            L + A++ F+    +   E E +       +V+  +++       +QE  +   +++ K 
Sbjct: 65   LLLAALVSFVLAWFE---EGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121

Query: 162  MVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRIIS--SHGCKVDNSSLT 217
              P+   VIR   K   +I A ++V GD+VEV  GD+VPADLR+I   S   +VD S LT
Sbjct: 122  YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181

Query: 218  GESEPQTRSPEFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASG 274
            GES   T+  E   +      + +N+ F  TN   G A G+ +ATG  T +G+I +  + 
Sbjct: 182  GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241

Query: 275  LEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IG 324
            +E  RTP+  +++ F + ++     + V+ +V+++        G SWL   ++     + 
Sbjct: 242  VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301

Query: 325  IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 384
            + VA +PEGL A +T CL L  +RMARKN +V++L +VETLG TS ICSDKTGTLT N+M
Sbjct: 302  LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361

Query: 385  TVAHMWFDNQ-------IHE---ADTTEDQSGATFDKRSPT----WTALSRIAGLCNRAV 430
            +V  M+   +       +HE   + TT    G       P     +  L  +A +C    
Sbjct: 362  SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421

Query: 431  FKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRN 472
              A   N +    +  G+A+E+AL   +E                   +C +V K   R 
Sbjct: 422  DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRK 481

Query: 473  PKVAEIPFNSTNKYQLSIHEREDSP----QSHVLVMKGAPERILDRCSTILVQGKEIPLD 528
                E    S ++  +S++     P    Q   + +KGAPE +++RCS++ V  +  PL 
Sbjct: 482  EFTLEF---SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLT 538

Query: 529  KEMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLM 586
               ++       + G   +  R L     + P  K        +  + + T+ L FVG +
Sbjct: 539  PTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETD-LTFVGCV 597

Query: 587  SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLN 646
             M+DPPR  V   + +C  AGI+V+M+TGD+  TA AI + +GI  +     ED+A +  
Sbjct: 598  GMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVAGK-- 651

Query: 647  IPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQG 706
                             G +  D++ EQ  +  +  T   FAR  P  K  IVE  Q   
Sbjct: 652  --------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHKSRIVENLQSFN 695

Query: 707  AIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIF 766
             I A+TGDGVND+PALKKA+IGIAMG SG+ V+K AA+M+L DDNFASIV  VEEGR I+
Sbjct: 696  EITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIY 754

Query: 767  DNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAES 826
             N+K+ I Y ++SN+ E+    L  I  +P  L  V +L ++L TD +PA +L +   + 
Sbjct: 755  SNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDL 814

Query: 827  DIMKRQPRNSQTDKLVNERLI--SMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIR 884
            DIM++ PR S  + L++  L    +A G    +  +     +FV  AE   +    L   
Sbjct: 815  DIMEKLPR-SPREALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNF 873

Query: 885  LDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQ 944
            L   +   N L      E  +E R        T   + +V ++  + +   +   S+ + 
Sbjct: 874  LKCSED--NPLFAGIDCE-VFESRFPT-----TMALSVLVTIEMCNALNSVSENQSLLRM 925

Query: 945  -GMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRK 1003
                N  L+  +    AL   +   P + +  ++ PL    W      SL + + DE  K
Sbjct: 926  PPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVILLDEALK 985

Query: 1004 LILRR------YPG 1011
             + R       YPG
Sbjct: 986  YLSRNHMHACLYPG 999


>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
            sapiens]
          Length = 999

 Score =  377 bits (967), Expect = e-104
 Identities = 304/1026 (29%), Positives = 481/1026 (46%), Gaps = 97/1026 (9%)

Query: 42   HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 101
            H L   ++ R + V    GL+  +      R GPN L        W     Q       +
Sbjct: 5    HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64

Query: 102  LWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKN 161
            L + A++ F+    +   E E +       +V+  +++       +QE  +   +++ K 
Sbjct: 65   LLLAALVSFVLAWFE---EGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121

Query: 162  MVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRIIS--SHGCKVDNSSLT 217
              P+   VIR   K   +I A ++V GD+VEV  GD+VPADLR+I   S   +VD S LT
Sbjct: 122  YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181

Query: 218  GESEPQTRSPEFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASG 274
            GES   T+  E   +      + +N+ F  TN   G A G+ +ATG  T +G+I +  + 
Sbjct: 182  GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241

Query: 275  LEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IG 324
            +E  RTP+  +++ F + ++     + V+ +V+++        G SWL   ++     + 
Sbjct: 242  VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301

Query: 325  IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 384
            + VA +PEGL A +T CL L  +RMARKN +V++L +VETLG TS ICSDKTGTLT N+M
Sbjct: 302  LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361

Query: 385  TVAHMWFDNQ-------IHE---ADTTEDQSGATFDKRSPT----WTALSRIAGLCNRAV 430
            +V  M+   +       +HE   + TT    G       P     +  L  +A +C    
Sbjct: 362  SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421

Query: 431  FKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRN 472
              A   N +    +  G+A+E+AL   +E                   +C +V K   R 
Sbjct: 422  DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRK 481

Query: 473  PKVAEIPFNSTNKYQLSIHEREDSP----QSHVLVMKGAPERILDRCSTILVQGKEIPLD 528
                E    S ++  +S++     P    Q   + +KGAPE +++RCS++ V  +  PL 
Sbjct: 482  EFTLEF---SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLT 538

Query: 529  KEMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLM 586
               ++       + G   +  R L     + P  K        +  + + T+ L FVG +
Sbjct: 539  PTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETD-LTFVGCV 597

Query: 587  SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLN 646
             M+DPPR  V   + +C  AGI+V+M+TGD+  TA AI + +GI  +     ED+A +  
Sbjct: 598  GMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVAGK-- 651

Query: 647  IPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQG 706
                             G +  D++ EQ  +  +  T   FAR  P  K  IVE  Q   
Sbjct: 652  --------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHKSRIVENLQSFN 695

Query: 707  AIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIF 766
             I A+TGDGVND+PALKKA+IGIAMG SG+ V+K AA+M+L DDNFASIV  VEEGR I+
Sbjct: 696  EITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIY 754

Query: 767  DNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAES 826
             N+K+ I Y ++SN+ E+    L  I  +P  L  V +L ++L TD +PA +L +   + 
Sbjct: 755  SNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDL 814

Query: 827  DIMKRQPRNSQTDKLVNERLI--SMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIR 884
            DIM++ PR S  + L++  L    +A G    +  +     +FV  AE   +    L   
Sbjct: 815  DIMEKLPR-SPREALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNF 873

Query: 885  LDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQ 944
            L   +   N L      E  +E R        T   + +V ++  + +   +   S+ + 
Sbjct: 874  LKCSED--NPLFAGIDCE-VFESRFPT-----TMALSVLVTIEMCNALNSVSENQSLLRM 925

Query: 945  -GMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRK 1003
                N  L+  +    AL   +   P + +  ++ PL    W      SL + + DE  K
Sbjct: 926  PPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVILLDEALK 985

Query: 1004 LILRRY 1009
             + R +
Sbjct: 986  YLSRNH 991


>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
            sapiens]
          Length = 998

 Score =  377 bits (967), Expect = e-104
 Identities = 304/1026 (29%), Positives = 481/1026 (46%), Gaps = 97/1026 (9%)

Query: 42   HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 101
            H L   ++ R + V    GL+  +      R GPN L        W     Q       +
Sbjct: 5    HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64

Query: 102  LWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKN 161
            L + A++ F+    +   E E +       +V+  +++       +QE  +   +++ K 
Sbjct: 65   LLLAALVSFVLAWFE---EGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121

Query: 162  MVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRIIS--SHGCKVDNSSLT 217
              P+   VIR   K   +I A ++V GD+VEV  GD+VPADLR+I   S   +VD S LT
Sbjct: 122  YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181

Query: 218  GESEPQTRSPEFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASG 274
            GES   T+  E   +      + +N+ F  TN   G A G+ +ATG  T +G+I +  + 
Sbjct: 182  GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241

Query: 275  LEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IG 324
            +E  RTP+  +++ F + ++     + V+ +V+++        G SWL   ++     + 
Sbjct: 242  VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301

Query: 325  IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 384
            + VA +PEGL A +T CL L  +RMARKN +V++L +VETLG TS ICSDKTGTLT N+M
Sbjct: 302  LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361

Query: 385  TVAHMWFDNQ-------IHE---ADTTEDQSGATFDKRSPT----WTALSRIAGLCNRAV 430
            +V  M+   +       +HE   + TT    G       P     +  L  +A +C    
Sbjct: 362  SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421

Query: 431  FKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRN 472
              A   N +    +  G+A+E+AL   +E                   +C +V K   R 
Sbjct: 422  DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRK 481

Query: 473  PKVAEIPFNSTNKYQLSIHEREDSP----QSHVLVMKGAPERILDRCSTILVQGKEIPLD 528
                E    S ++  +S++     P    Q   + +KGAPE +++RCS++ V  +  PL 
Sbjct: 482  EFTLEF---SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLT 538

Query: 529  KEMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLM 586
               ++       + G   +  R L     + P  K        +  + + T+ L FVG +
Sbjct: 539  PTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETD-LTFVGCV 597

Query: 587  SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLN 646
             M+DPPR  V   + +C  AGI+V+M+TGD+  TA AI + +GI  +     ED+A +  
Sbjct: 598  GMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVAGK-- 651

Query: 647  IPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQG 706
                             G +  D++ EQ  +  +  T   FAR  P  K  IVE  Q   
Sbjct: 652  --------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHKSRIVENLQSFN 695

Query: 707  AIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIF 766
             I A+TGDGVND+PALKKA+IGIAMG SG+ V+K AA+M+L DDNFASIV  VEEGR I+
Sbjct: 696  EITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIY 754

Query: 767  DNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAES 826
             N+K+ I Y ++SN+ E+    L  I  +P  L  V +L ++L TD +PA +L +   + 
Sbjct: 755  SNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDL 814

Query: 827  DIMKRQPRNSQTDKLVNERLI--SMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIR 884
            DIM++ PR S  + L++  L    +A G    +  +     +FV  AE   +    L   
Sbjct: 815  DIMEKLPR-SPREALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNF 873

Query: 885  LDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQ 944
            L   +   N L      E  +E R        T   + +V ++  + +   +   S+ + 
Sbjct: 874  LKCSED--NPLFAGIDCE-VFESRFPT-----TMALSVLVTIEMCNALNSVSENQSLLRM 925

Query: 945  -GMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRK 1003
                N  L+  +    AL   +   P + +  ++ PL    W      SL + + DE  K
Sbjct: 926  PPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVILLDEALK 985

Query: 1004 LILRRY 1009
             + R +
Sbjct: 986  YLSRNH 991


>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo
           sapiens]
          Length = 939

 Score =  375 bits (964), Expect = e-104
 Identities = 266/847 (31%), Positives = 426/847 (50%), Gaps = 81/847 (9%)

Query: 43  KLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILL 102
           +L + E+    Q DL  GL         A  G N        P W K+  Q      +LL
Sbjct: 28  ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87

Query: 103 WIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNM 162
              A++  L +    A+            + +A +++VT  F   QE +S K ++    +
Sbjct: 88  LASAVISVLMHQFDDAVS-----------ITVAILIVVTVAF--VQEYRSEKSLEELSKL 134

Query: 163 VPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEP 222
           VP +   +REG+     A ++V GD V +  GDRVPADLR+  +    +D SSLTGE+ P
Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194

Query: 223 QTR----SPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVG 278
            ++     P  T+ +     NI F  T    G A+G+VI TG+ +  G +  +    E  
Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254

Query: 279 RTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATV 338
           +TP+   ++   + ++  +  +     ++  +LG   LE     + + VA +PEGL   V
Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314

Query: 339 TVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEA 398
           TV L L   RM +K  +VK L  VETLG  + ICSDKTGTLT+N MTV H++  + +H  
Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374

Query: 399 DTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQE----NISVSKRDTA-GDASESA 453
            T     G  +++          + G  N AV +  +     N +V + +T  G  +E A
Sbjct: 375 VT-----GVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGA 429

Query: 454 LLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQL--SIHE-REDSPQSHVLVMKGAPER 510
           L+  + +  G     +D   K AE PF+S  K+     +H  ++D P+  +  MKGA E+
Sbjct: 430 LI-ALAMKMGLDGLQQDYIRK-AEYPFSSEQKWMAVKCVHRTQQDRPE--ICFMKGAYEQ 485

Query: 511 ILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDT 570
           ++  C+T   +G+ + L ++ +D +Q     +G  G RVL      L SG          
Sbjct: 486 VIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLA-----LASGP--------- 531

Query: 571 DELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGI 630
            EL     +L F+GL+ +IDPPR  V +AV    ++G+ + M+TGD   TA AIA  +G+
Sbjct: 532 -ELG----QLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL 586

Query: 631 ISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFART 690
            S+ +++V                         G ++  M  +QL +I+      VF R 
Sbjct: 587 YSKTSQSVS------------------------GEEIDAMDVQQLSQIVPKVA--VFYRA 620

Query: 691 SPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDD 750
           SP+ K+ I++  Q+ G++VA+TGDGVND+ ALK ADIG+AMG +G+DV K+AADMIL+DD
Sbjct: 621 SPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDD 680

Query: 751 NFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLG 810
           +F +I++ +EEG+ I++N+K  + + L+++I  +T   L  + N P PL  + IL I++ 
Sbjct: 681 DFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINII 740

Query: 811 TDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVIL 870
            D  PA SL  E  + D++++ PRN +   L    ++ +    I  I   G  F ++  L
Sbjct: 741 MDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGTLFVFWREL 798

Query: 871 AENGFLP 877
            +N   P
Sbjct: 799 RDNVITP 805


>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo
           sapiens]
          Length = 949

 Score =  375 bits (964), Expect = e-104
 Identities = 266/847 (31%), Positives = 426/847 (50%), Gaps = 81/847 (9%)

Query: 43  KLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILL 102
           +L + E+    Q DL  GL         A  G N        P W K+  Q      +LL
Sbjct: 28  ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87

Query: 103 WIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNM 162
              A++  L +    A+            + +A +++VT  F   QE +S K ++    +
Sbjct: 88  LASAVISVLMHQFDDAVS-----------ITVAILIVVTVAF--VQEYRSEKSLEELSKL 134

Query: 163 VPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEP 222
           VP +   +REG+     A ++V GD V +  GDRVPADLR+  +    +D SSLTGE+ P
Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194

Query: 223 QTR----SPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVG 278
            ++     P  T+ +     NI F  T    G A+G+VI TG+ +  G +  +    E  
Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254

Query: 279 RTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATV 338
           +TP+   ++   + ++  +  +     ++  +LG   LE     + + VA +PEGL   V
Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314

Query: 339 TVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEA 398
           TV L L   RM +K  +VK L  VETLG  + ICSDKTGTLT+N MTV H++  + +H  
Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374

Query: 399 DTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQE----NISVSKRDTA-GDASESA 453
            T     G  +++          + G  N AV +  +     N +V + +T  G  +E A
Sbjct: 375 VT-----GVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGA 429

Query: 454 LLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQL--SIHE-REDSPQSHVLVMKGAPER 510
           L+  + +  G     +D   K AE PF+S  K+     +H  ++D P+  +  MKGA E+
Sbjct: 430 LI-ALAMKMGLDGLQQDYIRK-AEYPFSSEQKWMAVKCVHRTQQDRPE--ICFMKGAYEQ 485

Query: 511 ILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDT 570
           ++  C+T   +G+ + L ++ +D +Q     +G  G RVL      L SG          
Sbjct: 486 VIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLA-----LASGP--------- 531

Query: 571 DELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGI 630
            EL     +L F+GL+ +IDPPR  V +AV    ++G+ + M+TGD   TA AIA  +G+
Sbjct: 532 -ELG----QLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL 586

Query: 631 ISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFART 690
            S+ +++V                         G ++  M  +QL +I+      VF R 
Sbjct: 587 YSKTSQSVS------------------------GEEIDAMDVQQLSQIVPKVA--VFYRA 620

Query: 691 SPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDD 750
           SP+ K+ I++  Q+ G++VA+TGDGVND+ ALK ADIG+AMG +G+DV K+AADMIL+DD
Sbjct: 621 SPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDD 680

Query: 751 NFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLG 810
           +F +I++ +EEG+ I++N+K  + + L+++I  +T   L  + N P PL  + IL I++ 
Sbjct: 681 DFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINII 740

Query: 811 TDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVIL 870
            D  PA SL  E  + D++++ PRN +   L    ++ +    I  I   G  F ++  L
Sbjct: 741 MDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGTLFVFWREL 798

Query: 871 AENGFLP 877
            +N   P
Sbjct: 799 RDNVITP 805


>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo
           sapiens]
          Length = 888

 Score =  375 bits (964), Expect = e-104
 Identities = 266/847 (31%), Positives = 426/847 (50%), Gaps = 81/847 (9%)

Query: 43  KLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILL 102
           +L + E+    Q DL  GL         A  G N        P W K+  Q      +LL
Sbjct: 28  ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87

Query: 103 WIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNM 162
              A++  L +    A+            + +A +++VT  F   QE +S K ++    +
Sbjct: 88  LASAVISVLMHQFDDAVS-----------ITVAILIVVTVAF--VQEYRSEKSLEELSKL 134

Query: 163 VPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEP 222
           VP +   +REG+     A ++V GD V +  GDRVPADLR+  +    +D SSLTGE+ P
Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194

Query: 223 QTR----SPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVG 278
            ++     P  T+ +     NI F  T    G A+G+VI TG+ +  G +  +    E  
Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254

Query: 279 RTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATV 338
           +TP+   ++   + ++  +  +     ++  +LG   LE     + + VA +PEGL   V
Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314

Query: 339 TVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEA 398
           TV L L   RM +K  +VK L  VETLG  + ICSDKTGTLT+N MTV H++  + +H  
Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374

Query: 399 DTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQE----NISVSKRDTA-GDASESA 453
            T     G  +++          + G  N AV +  +     N +V + +T  G  +E A
Sbjct: 375 VT-----GVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGA 429

Query: 454 LLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQL--SIHE-REDSPQSHVLVMKGAPER 510
           L+  + +  G     +D   K AE PF+S  K+     +H  ++D P+  +  MKGA E+
Sbjct: 430 LI-ALAMKMGLDGLQQDYIRK-AEYPFSSEQKWMAVKCVHRTQQDRPE--ICFMKGAYEQ 485

Query: 511 ILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDT 570
           ++  C+T   +G+ + L ++ +D +Q     +G  G RVL      L SG          
Sbjct: 486 VIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLA-----LASGP--------- 531

Query: 571 DELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGI 630
            EL     +L F+GL+ +IDPPR  V +AV    ++G+ + M+TGD   TA AIA  +G+
Sbjct: 532 -ELG----QLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL 586

Query: 631 ISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFART 690
            S+ +++V                         G ++  M  +QL +I+      VF R 
Sbjct: 587 YSKTSQSVS------------------------GEEIDAMDVQQLSQIVPKVA--VFYRA 620

Query: 691 SPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDD 750
           SP+ K+ I++  Q+ G++VA+TGDGVND+ ALK ADIG+AMG +G+DV K+AADMIL+DD
Sbjct: 621 SPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDD 680

Query: 751 NFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLG 810
           +F +I++ +EEG+ I++N+K  + + L+++I  +T   L  + N P PL  + IL I++ 
Sbjct: 681 DFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINII 740

Query: 811 TDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVIL 870
            D  PA SL  E  + D++++ PRN +   L    ++ +    I  I   G  F ++  L
Sbjct: 741 MDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGTLFVFWREL 798

Query: 871 AENGFLP 877
            +N   P
Sbjct: 799 RDNVITP 805


>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo
           sapiens]
          Length = 919

 Score =  375 bits (964), Expect = e-104
 Identities = 266/847 (31%), Positives = 426/847 (50%), Gaps = 81/847 (9%)

Query: 43  KLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILL 102
           +L + E+    Q DL  GL         A  G N        P W K+  Q      +LL
Sbjct: 28  ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87

Query: 103 WIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNM 162
              A++  L +    A+            + +A +++VT  F   QE +S K ++    +
Sbjct: 88  LASAVISVLMHQFDDAVS-----------ITVAILIVVTVAF--VQEYRSEKSLEELSKL 134

Query: 163 VPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEP 222
           VP +   +REG+     A ++V GD V +  GDRVPADLR+  +    +D SSLTGE+ P
Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194

Query: 223 QTR----SPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVG 278
            ++     P  T+ +     NI F  T    G A+G+VI TG+ +  G +  +    E  
Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254

Query: 279 RTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATV 338
           +TP+   ++   + ++  +  +     ++  +LG   LE     + + VA +PEGL   V
Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314

Query: 339 TVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEA 398
           TV L L   RM +K  +VK L  VETLG  + ICSDKTGTLT+N MTV H++  + +H  
Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374

Query: 399 DTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQE----NISVSKRDTA-GDASESA 453
            T     G  +++          + G  N AV +  +     N +V + +T  G  +E A
Sbjct: 375 VT-----GVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGA 429

Query: 454 LLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQL--SIHE-REDSPQSHVLVMKGAPER 510
           L+  + +  G     +D   K AE PF+S  K+     +H  ++D P+  +  MKGA E+
Sbjct: 430 LI-ALAMKMGLDGLQQDYIRK-AEYPFSSEQKWMAVKCVHRTQQDRPE--ICFMKGAYEQ 485

Query: 511 ILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDT 570
           ++  C+T   +G+ + L ++ +D +Q     +G  G RVL      L SG          
Sbjct: 486 VIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLA-----LASGP--------- 531

Query: 571 DELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGI 630
            EL     +L F+GL+ +IDPPR  V +AV    ++G+ + M+TGD   TA AIA  +G+
Sbjct: 532 -ELG----QLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL 586

Query: 631 ISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFART 690
            S+ +++V                         G ++  M  +QL +I+      VF R 
Sbjct: 587 YSKTSQSVS------------------------GEEIDAMDVQQLSQIVPKVA--VFYRA 620

Query: 691 SPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDD 750
           SP+ K+ I++  Q+ G++VA+TGDGVND+ ALK ADIG+AMG +G+DV K+AADMIL+DD
Sbjct: 621 SPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDD 680

Query: 751 NFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLG 810
           +F +I++ +EEG+ I++N+K  + + L+++I  +T   L  + N P PL  + IL I++ 
Sbjct: 681 DFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINII 740

Query: 811 TDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVIL 870
            D  PA SL  E  + D++++ PRN +   L    ++ +    I  I   G  F ++  L
Sbjct: 741 MDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGTLFVFWREL 798

Query: 871 AENGFLP 877
            +N   P
Sbjct: 799 RDNVITP 805


>gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo
            sapiens]
          Length = 997

 Score =  370 bits (950), Expect = e-102
 Identities = 299/1032 (28%), Positives = 494/1032 (47%), Gaps = 110/1032 (10%)

Query: 42   HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSI- 100
            H  +++E+   + V+ S GL+ ++ + +  R G N L P       ++   + F    + 
Sbjct: 5    HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63

Query: 101  LLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFK 160
            +L + A + F+    +   E E +        V+  +++       +QE  +   +++ K
Sbjct: 64   ILLLAACISFVLAWFE---EGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120

Query: 161  NMVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRI--ISSHGCKVDNSSL 216
               P+   V R+  K   +I A+++V GD+VE+  GD+VPAD+R+  I S   +VD S L
Sbjct: 121  EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180

Query: 217  TGESEPQTRSPEFTHENPL--------ETRNICFFSTNCVEGTARGIVIATGDRTVMGRI 268
            TGES    +     H +P+        + +N+ F  TN   G A G+V+ATG  T +G+I
Sbjct: 181  TGESVSVIK-----HTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKI 235

Query: 269  ATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL 322
                   E  RTP+  +++ F + ++ V   + ++ +++++      + G SW+   I+ 
Sbjct: 236  RDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYY 295

Query: 323  ----IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 378
                + + VA +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGT
Sbjct: 296  FKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGT 355

Query: 379  LTQNRMTVAHMWFDNQIHEADTTEDQ----SGATF---------DK--RSPTWTALSRIA 423
            LT N+M+V  M+  +++ E DT        +G+T+         DK      +  L  +A
Sbjct: 356  LTTNQMSVCRMFILDRV-EGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELA 414

Query: 424  GLCNRAVFKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSV 465
             +C      A   N +    +  G+A+E+AL   +E                   +C SV
Sbjct: 415  TICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSV 474

Query: 466  RKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQS---HVLVMKGAPERILDRCSTILVQG 522
             K   +     E    S ++  +S++   + P       + +KGAPE ++DRC+ I V  
Sbjct: 475  IKQLMKKEFTLEF---SRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGS 531

Query: 523  KEIPLDKEMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKL 580
             ++P+   ++    +   E G   +  R L     + P  +     +   + + + T  L
Sbjct: 532  TKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETN-L 590

Query: 581  CFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVED 640
             FVG + M+DPPR  V  +V  CR AGI+VIM+TGD+  TA AI + +GI  +  +    
Sbjct: 591  TFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSK 650

Query: 641  IAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVE 700
              A       ++NP                 S Q D  L       FAR  P  K  IVE
Sbjct: 651  --AFTGREFDELNP-----------------SAQRDACLNARC---FARVEPSHKSKIVE 688

Query: 701  GCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVE 760
              Q    I A+TGDGVND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV  VE
Sbjct: 689  FLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVE 747

Query: 761  EGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLA 820
            EGR I++N+K+ I Y ++SN+ E+    L      P  L  V +L ++L TD +PA +L 
Sbjct: 748  EGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALG 807

Query: 821  YEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMI--QALGGFFTYFVILAENGFLPS 878
            +   + DIM + PRN + + L++  L    Y  IG     A  G   ++ I A+ G    
Sbjct: 808  FNPPDLDIMNKPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGG---P 862

Query: 879  RLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRR 938
            R+   +L    +   D  D  G +    +         T   + +V ++  + +   +  
Sbjct: 863  RVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYP----MTMALSVLVTIEMCNALNSLSEN 918

Query: 939  NSVFQQ-GMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFI 997
             S+ +    +N  L+  +    +L   + Y   + +  ++ PL VT W      SL + +
Sbjct: 919  QSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVIL 978

Query: 998  YDEVRKLILRRY 1009
             DE  K + R Y
Sbjct: 979  MDETLKFVARNY 990


>gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [Homo
            sapiens]
          Length = 1042

 Score =  370 bits (950), Expect = e-102
 Identities = 299/1032 (28%), Positives = 494/1032 (47%), Gaps = 110/1032 (10%)

Query: 42   HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSI- 100
            H  +++E+   + V+ S GL+ ++ + +  R G N L P       ++   + F    + 
Sbjct: 5    HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63

Query: 101  LLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFK 160
            +L + A + F+    +   E E +        V+  +++       +QE  +   +++ K
Sbjct: 64   ILLLAACISFVLAWFE---EGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120

Query: 161  NMVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRI--ISSHGCKVDNSSL 216
               P+   V R+  K   +I A+++V GD+VE+  GD+VPAD+R+  I S   +VD S L
Sbjct: 121  EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180

Query: 217  TGESEPQTRSPEFTHENPL--------ETRNICFFSTNCVEGTARGIVIATGDRTVMGRI 268
            TGES    +     H +P+        + +N+ F  TN   G A G+V+ATG  T +G+I
Sbjct: 181  TGESVSVIK-----HTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKI 235

Query: 269  ATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL 322
                   E  RTP+  +++ F + ++ V   + ++ +++++      + G SW+   I+ 
Sbjct: 236  RDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYY 295

Query: 323  ----IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 378
                + + VA +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGT
Sbjct: 296  FKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGT 355

Query: 379  LTQNRMTVAHMWFDNQIHEADTTEDQ----SGATF---------DK--RSPTWTALSRIA 423
            LT N+M+V  M+  +++ E DT        +G+T+         DK      +  L  +A
Sbjct: 356  LTTNQMSVCRMFILDRV-EGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELA 414

Query: 424  GLCNRAVFKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSV 465
             +C      A   N +    +  G+A+E+AL   +E                   +C SV
Sbjct: 415  TICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSV 474

Query: 466  RKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQS---HVLVMKGAPERILDRCSTILVQG 522
             K   +     E    S ++  +S++   + P       + +KGAPE ++DRC+ I V  
Sbjct: 475  IKQLMKKEFTLEF---SRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGS 531

Query: 523  KEIPLDKEMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKL 580
             ++P+   ++    +   E G   +  R L     + P  +     +   + + + T  L
Sbjct: 532  TKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETN-L 590

Query: 581  CFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVED 640
             FVG + M+DPPR  V  +V  CR AGI+VIM+TGD+  TA AI + +GI  +  +    
Sbjct: 591  TFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSK 650

Query: 641  IAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVE 700
              A       ++NP                 S Q D  L       FAR  P  K  IVE
Sbjct: 651  --AFTGREFDELNP-----------------SAQRDACLNARC---FARVEPSHKSKIVE 688

Query: 701  GCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVE 760
              Q    I A+TGDGVND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV  VE
Sbjct: 689  FLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVE 747

Query: 761  EGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLA 820
            EGR I++N+K+ I Y ++SN+ E+    L      P  L  V +L ++L TD +PA +L 
Sbjct: 748  EGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALG 807

Query: 821  YEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMI--QALGGFFTYFVILAENGFLPS 878
            +   + DIM + PRN + + L++  L    Y  IG     A  G   ++ I A+ G    
Sbjct: 808  FNPPDLDIMNKPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGG---P 862

Query: 879  RLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRR 938
            R+   +L    +   D  D  G +    +         T   + +V ++  + +   +  
Sbjct: 863  RVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYP----MTMALSVLVTIEMCNALNSLSEN 918

Query: 939  NSVFQQ-GMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFI 997
             S+ +    +N  L+  +    +L   + Y   + +  ++ PL VT W      SL + +
Sbjct: 919  QSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVIL 978

Query: 998  YDEVRKLILRRY 1009
             DE  K + R Y
Sbjct: 979  MDETLKFVARNY 990


>gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo
           sapiens]
          Length = 946

 Score =  361 bits (926), Expect = 2e-99
 Identities = 274/869 (31%), Positives = 415/869 (47%), Gaps = 104/869 (11%)

Query: 4   GAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDH---KLSLDELGRKYQVDLSKG 60
           G GR+Y       E     ++ + K +++ KK  A+      K   ++L R + VDL  G
Sbjct: 17  GGGRQYQALEKDEEEALIDEQSELKAIEKEKKVTALPPKEACKCQKEDLARAFCVDLHTG 76

Query: 61  LTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAME 120
           L+           G N      + P W K+  Q      +LL   A++  L    + A  
Sbjct: 77  LSEFSVTQRRLAHGWNEFVADNSEPVWKKYLDQFKNPLILLLLGSALVSVLTKEYEDA-- 134

Query: 121 DEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINA 180
                      V +A  V+V    ++ QE +S K ++    MVP +   +REG+   + A
Sbjct: 135 -----------VSIATAVLVVVTVAFIQEYRSEKSLEELTKMVPPECNCLREGKLQHLLA 183

Query: 181 EEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEP--QTRSPEFTHENPLETR 238
            E+V GD+V +  GDR+PAD+R+       VD SS TGE+EP  +T SP     +     
Sbjct: 184 RELVPGDVVSLSIGDRIPADIRLTEVTDLLVDESSFTGEAEPCSKTDSPLTGGGDLTTLS 243

Query: 239 NICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAV 298
           NI F  T    G  +G+VI TG+ +  G +  +    E  +TP+   ++   + +T   +
Sbjct: 244 NIVFMGTLVQYGRGQGVVIGTGESSQFGEVFKMMQAEETPKTPLQKSMDRLGKQLT---L 300

Query: 299 FLGVSFFVLSLILGYSWLEAV----IFLIGI--IVANVPEGLLATVTVCLTLTAKRMARK 352
           F   SF ++ LI+   W +      +F IG+   VA +PEGL   V V L L   RMA+K
Sbjct: 301 F---SFGIIGLIMLIGWSQGKQLLSMFTIGVSLAVAAIPEGLPIVVMVTLVLGVLRMAKK 357

Query: 353 NCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKR 412
             +VK L  VETLG  S +CSDKTGTLT N MTV  +   + +       + SG  +D +
Sbjct: 358 RVIVKKLPIVETLGCCSVLCSDKTGTLTANEMTVTQLVTSDGLRA-----EVSGVGYDGQ 412

Query: 413 S-----PTWTALSRIAGLCNRAVFKAG--QENISVSKRDTAGDASESALLK-CIELSCGS 464
                 P+   +   + +    + +AG    N  + K    G  +E AL+   +++    
Sbjct: 413 GTVCLLPSKEVIKEFSNVSVGKLVEAGCVANNAVIRKNAVMGQPTEGALMALAMKMDLSD 472

Query: 465 VRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKE 524
           ++    R     EIPF+S  K+       +   Q  +  MKGA E ++  C+     G  
Sbjct: 473 IKNSYIRKK---EIPFSSEQKWMAVKCSLKTEDQEDIYFMKGALEEVIRYCTMYNNGGIP 529

Query: 525 IPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVG 584
           +PL  + +         +G LG RVL      L SG           EL     +L F+G
Sbjct: 530 LPLTPQQRSFCLQEEKRMGSLGLRVLA-----LASGP----------ELG----RLTFLG 570

Query: 585 LMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAAR 644
           L+ +IDPPR  V +AV     +G+ V M+TGD   TA AI + +G+ +            
Sbjct: 571 LVGIIDPPRVGVKEAVQVLSESGVSVKMITGDALETALAIGRNIGLCN------------ 618

Query: 645 LNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTE------IVFARTSPQQKLII 698
                                 L+ M+ E++D + K           VF RTSP+ KL I
Sbjct: 619 --------------------GKLQAMSGEEVDSVEKGELADRVGKVSVFFRTSPKHKLKI 658

Query: 699 VEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTG 758
           ++  Q  GAIVA+TGDGVND+ ALK ADIGIAMG +G+DVSK+AA+MIL+DD+F++I+  
Sbjct: 659 IKALQESGAIVAMTGDGVNDAVALKSADIGIAMGQTGTDVSKEAANMILVDDDFSAIMNA 718

Query: 759 VEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAIS 818
           VEEG+ IF N+K  + + L+++I  ++   L  + N+P PL  + IL I++  D  PA S
Sbjct: 719 VEEGKGIFYNIKNFVRFQLSTSISALSLITLSTVFNLPSPLNAMQILWINIIMDGPPAQS 778

Query: 819 LAYEAAESDIMKRQPRNSQTDKLVNERLI 847
           L  E  + D   RQP  S  D +++  LI
Sbjct: 779 LGVEPVDKDAF-RQPPRSVRDTILSRALI 806


>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [Homo
            sapiens]
          Length = 994

 Score =  360 bits (925), Expect = 3e-99
 Identities = 300/1039 (28%), Positives = 474/1039 (45%), Gaps = 117/1039 (11%)

Query: 42   HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 101
            H  + +E    + V  + GLT  + +  L + G N L        W     Q       +
Sbjct: 5    HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 64

Query: 102  LWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKN 161
            L + A + F+    +   E E +        V+  ++I       +QE  +   +++ K 
Sbjct: 65   LLLAACISFVLAWFE---EGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKE 121

Query: 162  MVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRI--ISSHGCKVDNSSLT 217
              P+   V R   K   +I A ++V GD+VEV  GD+VPAD+RI  I S   +VD S LT
Sbjct: 122  YEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILT 181

Query: 218  GESEPQTRSPEFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASG 274
            GES    +  E   +      + +N+ F  TN   G A GIV  TG  T +G+I    + 
Sbjct: 182  GESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAA 241

Query: 275  LEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IG 324
             E  +TP+  +++ F + ++ V   + V+ +++++      + G SW    I+     + 
Sbjct: 242  TEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVA 301

Query: 325  IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 384
            + VA +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M
Sbjct: 302  LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361

Query: 385  TVAHMWFD----------NQIHEADTTEDQSGATFDKRSPT----WTALSRIAGLCNRAV 430
            +V  M+            N+     +T    G       P     +  L  +A +C    
Sbjct: 362  SVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCN 421

Query: 431  FKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRN 472
              +   N +    +  G+A+E+AL   +E                   +C SV  +R   
Sbjct: 422  DSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSV--IRQLM 479

Query: 473  PKVAEIPFNSTNKYQLSIHEREDSPQSHV---LVMKGAPERILDRCSTILVQGKEIPLDK 529
             K   + F+   K          S ++ V   + +KGAPE ++DRC+ + V    +PL  
Sbjct: 480  KKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTG 539

Query: 530  EMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMS 587
             +++       E G   +  R L     + P  +           L + T+ L FVG++ 
Sbjct: 540  PVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETD-LTFVGVVG 598

Query: 588  MIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNI 647
            M+DPPR  V  ++  CR AGI+VIM+TGD+  TA AI + +GI  E NE V D A     
Sbjct: 599  MLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGE-NEEVADRAYT--- 654

Query: 648  PMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGA 707
                            G +  D+   +  E  +      FAR  P  K  IVE  Q    
Sbjct: 655  ----------------GREFDDLPLAEQREACRR--ACCFARVEPSHKSKIVEYLQSYDE 696

Query: 708  IVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFD 767
            I A+TGDGVND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV  VEEGR I++
Sbjct: 697  ITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYN 755

Query: 768  NLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESD 827
            N+K+ I Y ++SN+ E+    L     +P  L  V +L ++L TD +PA +L +   + D
Sbjct: 756  NMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLD 815

Query: 828  IMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDW 887
            IM R PR+ +      E LIS      G +     FF Y  I    G++ +  +G    W
Sbjct: 816  IMDRPPRSPK------EPLIS------GWL-----FFRYMAI---GGYVGAATVGAAAWW 855

Query: 888  -----DDRTMNDLEDSYGQEWTYEQRKVVEFTCH--------TAFFASIVVVQWADLIIC 934
                 D   +N  + ++  + T +        C         T   + +V ++  + +  
Sbjct: 856  FLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMCNALNS 915

Query: 935  KTRRNSVFQQGMKNKILIFG-LLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSL 993
             +   S+ +      I + G +    +L   + Y   + +  ++  L +T W      SL
Sbjct: 916  LSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMVLKISL 975

Query: 994  LIFIYDEVRKLILRRYPGG 1012
             +   DE+ K + R Y  G
Sbjct: 976  PVIGLDEILKFVARNYLEG 994


>gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [Homo
            sapiens]
          Length = 1001

 Score =  360 bits (924), Expect = 4e-99
 Identities = 299/1036 (28%), Positives = 473/1036 (45%), Gaps = 117/1036 (11%)

Query: 42   HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 101
            H  + +E    + V  + GLT  + +  L + G N L        W     Q       +
Sbjct: 5    HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 64

Query: 102  LWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKN 161
            L + A + F+    +   E E +        V+  ++I       +QE  +   +++ K 
Sbjct: 65   LLLAACISFVLAWFE---EGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKE 121

Query: 162  MVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRI--ISSHGCKVDNSSLT 217
              P+   V R   K   +I A ++V GD+VEV  GD+VPAD+RI  I S   +VD S LT
Sbjct: 122  YEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILT 181

Query: 218  GESEPQTRSPEFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASG 274
            GES    +  E   +      + +N+ F  TN   G A GIV  TG  T +G+I    + 
Sbjct: 182  GESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAA 241

Query: 275  LEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IG 324
             E  +TP+  +++ F + ++ V   + V+ +++++      + G SW    I+     + 
Sbjct: 242  TEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVA 301

Query: 325  IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 384
            + VA +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M
Sbjct: 302  LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361

Query: 385  TVAHMWFD----------NQIHEADTTEDQSGATFDKRSPT----WTALSRIAGLCNRAV 430
            +V  M+            N+     +T    G       P     +  L  +A +C    
Sbjct: 362  SVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCN 421

Query: 431  FKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRN 472
              +   N +    +  G+A+E+AL   +E                   +C SV  +R   
Sbjct: 422  DSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSV--IRQLM 479

Query: 473  PKVAEIPFNSTNKYQLSIHEREDSPQSHV---LVMKGAPERILDRCSTILVQGKEIPLDK 529
             K   + F+   K          S ++ V   + +KGAPE ++DRC+ + V    +PL  
Sbjct: 480  KKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTG 539

Query: 530  EMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMS 587
             +++       E G   +  R L     + P  +           L + T+ L FVG++ 
Sbjct: 540  PVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETD-LTFVGVVG 598

Query: 588  MIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNI 647
            M+DPPR  V  ++  CR AGI+VIM+TGD+  TA AI + +GI  E NE V D A     
Sbjct: 599  MLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGE-NEEVADRAYT--- 654

Query: 648  PMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGA 707
                            G +  D+   +  E  +      FAR  P  K  IVE  Q    
Sbjct: 655  ----------------GREFDDLPLAEQREACRR--ACCFARVEPSHKSKIVEYLQSYDE 696

Query: 708  IVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFD 767
            I A+TGDGVND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV  VEEGR I++
Sbjct: 697  ITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYN 755

Query: 768  NLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESD 827
            N+K+ I Y ++SN+ E+    L     +P  L  V +L ++L TD +PA +L +   + D
Sbjct: 756  NMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLD 815

Query: 828  IMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDW 887
            IM R PR+ +      E LIS      G +     FF Y  I    G++ +  +G    W
Sbjct: 816  IMDRPPRSPK------EPLIS------GWL-----FFRYMAI---GGYVGAATVGAAAWW 855

Query: 888  -----DDRTMNDLEDSYGQEWTYEQRKVVEFTCH--------TAFFASIVVVQWADLIIC 934
                 D   +N  + ++  + T +        C         T   + +V ++  + +  
Sbjct: 856  FLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMCNALNS 915

Query: 935  KTRRNSVFQQGMKNKILIFG-LLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSL 993
             +   S+ +      I + G +    +L   + Y   + +  ++  L +T W      SL
Sbjct: 916  LSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMVLKISL 975

Query: 994  LIFIYDEVRKLILRRY 1009
             +   DE+ K + R Y
Sbjct: 976  PVIGLDEILKFVARNY 991


>gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 [Homo
            sapiens]
          Length = 1015

 Score =  341 bits (874), Expect = 2e-93
 Identities = 284/1022 (27%), Positives = 479/1022 (46%), Gaps = 117/1022 (11%)

Query: 42   HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSI- 100
            H  +++E+   + V+ S GL+ ++ + +  R G N L P       ++   + F    + 
Sbjct: 5    HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63

Query: 101  LLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFK 160
            +L + A + F+    +   E E +        V+  +++       +QE  +   +++ K
Sbjct: 64   ILLLAACISFVLAWFE---EGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120

Query: 161  NMVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTG 218
               P+   V R+  K   +I A+++V GD+VE+ G                  ++ S+  
Sbjct: 121  EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAG------------------ESVSVIK 162

Query: 219  ESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVG 278
             ++P    P   ++   + +N+ F  TN   G A G+V+ATG  T +G+I       E  
Sbjct: 163  HTDP-VPDPRAVNQ---DKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQE 218

Query: 279  RTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IGIIVA 328
            RTP+  +++ F + ++ V   + ++ +++++      + G SW+   I+     + + VA
Sbjct: 219  RTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVA 278

Query: 329  NVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAH 388
             +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M+V  
Sbjct: 279  AIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCR 338

Query: 389  MWFDNQIHEADTTEDQ----SGATF---------DK--RSPTWTALSRIAGLCNRAVFKA 433
            M+  +++ E DT        +G+T+         DK      +  L  +A +C      A
Sbjct: 339  MFILDRV-EGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSA 397

Query: 434  GQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRNPKV 475
               N +    +  G+A+E+AL   +E                   +C SV K   +    
Sbjct: 398  LDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFT 457

Query: 476  AEIPFNSTNKYQLSIHEREDSPQS---HVLVMKGAPERILDRCSTILVQGKEIPLDKEMQ 532
             E    S ++  +S++   + P       + +KGAPE ++DRC+ I V   ++P+   ++
Sbjct: 458  LEF---SRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVK 514

Query: 533  DAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMID 590
                +   E G   +  R L     + P  +     +   + + + T  L FVG + M+D
Sbjct: 515  QKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETN-LTFVGCVGMLD 573

Query: 591  PPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMS 650
            PPR  V  +V  CR AGI+VIM+TGD+  TA AI + +GI  +  +      A       
Sbjct: 574  PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSK--AFTGREFD 631

Query: 651  QVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVA 710
            ++NP                 S Q D  L       FAR  P  K  IVE  Q    I A
Sbjct: 632  ELNP-----------------SAQRDACLNARC---FARVEPSHKSKIVEFLQSFDEITA 671

Query: 711  VTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLK 770
            +TGDGVND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV  VEEGR I++N+K
Sbjct: 672  MTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMK 730

Query: 771  KSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMK 830
            + I Y ++SN+ E+    L      P  L  V +L ++L TD +PA +L +   + DIM 
Sbjct: 731  QFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMN 790

Query: 831  RQPRNSQTDKLVNERLISMAYGQIGMI--QALGGFFTYFVILAENGFLPSRLLGIRLDWD 888
            + PRN + + L++  L    Y  IG     A  G   ++ I A+ G    R+   +L   
Sbjct: 791  KPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGG---PRVSFYQLSHF 845

Query: 889  DRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQ-GMK 947
             +   D  D  G +    +         T   + +V ++  + +   +   S+ +    +
Sbjct: 846  LQCKEDNPDFEGVDCAIFESPYP----MTMALSVLVTIEMCNALNSLSENQSLLRMPPWE 901

Query: 948  NKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILR 1007
            N  L+  +    +L   + Y   + +  ++ PL VT W      SL + + DE  K + R
Sbjct: 902  NIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILMDETLKFVAR 961

Query: 1008 RY 1009
             Y
Sbjct: 962  NY 963


>gi|49249977 Na+/K+ -ATPase alpha 4 subunit isoform 2 [Homo sapiens]
          Length = 165

 Score =  289 bits (740), Expect = 8e-78
 Identities = 132/165 (80%), Positives = 150/165 (90%)

Query: 856  MIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTC 915
            MIQAL GFFTYFVILAENGF P  LLGIRL W+D+ +NDLEDSYGQ+WTYEQRKVVEFTC
Sbjct: 1    MIQALAGFFTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTC 60

Query: 916  HTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVAL 975
             TAFF +IVVVQWADLII KTRRNS+FQQGM+NK+LIFG+LEET LAAFLSY PGM VAL
Sbjct: 61   QTAFFVTIVVVQWADLIISKTRRNSLFQQGMRNKVLIFGILEETLLAAFLSYTPGMDVAL 120

Query: 976  RMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 1020
            RMYPLK+TWW CA PYS+LIF+YDE+RKL++R++P GWVE+ETYY
Sbjct: 121  RMYPLKITWWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY 165


>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo
           sapiens]
          Length = 1198

 Score =  258 bits (659), Expect = 2e-68
 Identities = 238/800 (29%), Positives = 376/800 (47%), Gaps = 115/800 (14%)

Query: 137 VVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDR 196
           VV+VT    + +E +   +    +    Q+  V+R G+ +QI   E+VVGD+ +VK GD 
Sbjct: 164 VVLVTAFNDWSKEKQFRGLQSRIEQ--EQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDL 221

Query: 197 VPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIV 256
           +PAD   I  +  K+D SSLTGES+   +S +   ++P+         T+ +EG+ R +V
Sbjct: 222 LPADGLFIQGNDLKIDESSLTGESDQVRKSVD---KDPM-----LLSGTHVMEGSGRMLV 273

Query: 257 IATGDRTVMGRIATL--ASGLEVGRTP---------IAMEIEHFIQL------------- 292
            A G  +  G I TL  A G E  +            AME++                  
Sbjct: 274 TAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEMQPLKSAEGGDADDRKKASM 333

Query: 293 -----------ITGVAVFLGVSFFVLS------LILGYS----------WLEAV------ 319
                      +T +AV +G +  V+S      L+L ++          WL         
Sbjct: 334 HKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQ 393

Query: 320 ----IFLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICS 373
                F+IG+  +V  VPEGL   VT+ L  + K+M + N LV++L+A ET+G+ + ICS
Sbjct: 394 YFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICS 453

Query: 374 DKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKA 433
           DKTGTLT NRMTV   +  + +H  +  +  S  T      T   L     + +    K 
Sbjct: 454 DKTGTLTTNRMTVVQAYVGD-VHYKEIPDPSSINT-----KTMELLINAIAINSAYTTKI 507

Query: 434 GQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNP--KVAEI-PFNSTNKYQLSI 490
                  +     G+ +E  LL  +         +R + P  K+ ++  FNS  K   ++
Sbjct: 508 LPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTV 567

Query: 491 HEREDSPQSHVLVMKGAPERILDRCSTILVQGKE--IPLDKEMQDAFQNAYMELGGLGER 548
            +  D  +S  +  KGA E +L +C  IL    E  +   ++  +  +     +   G R
Sbjct: 568 IKLPD--ESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLR 625

Query: 549 VLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGI 608
            +     + PS   P     D D  N    +L  + ++ + DP R  VP+A+ KC+ AGI
Sbjct: 626 TICVAYRDFPSSPEP-----DWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGI 680

Query: 609 KVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLK 668
            V MVTGD+  TA+AIA   GII  G +        L +   + N R         ++  
Sbjct: 681 TVRMVTGDNINTARAIAIKCGIIHPGEDF-------LCLEGKEFNRRIR-------NEKG 726

Query: 669 DMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGC-----QRQGAIVAVTGDGVNDSPALK 723
           ++  E++D+I       V AR+SP  K  +V+G        Q  +VAVTGDG ND PALK
Sbjct: 727 EIEQERIDKIWPKLR--VLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALK 784

Query: 724 KADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPE 783
           KAD+G AMGI+G+DV+K+A+D+IL DDNF+SIV  V  GR ++D++ K + + LT N+  
Sbjct: 785 KADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVA 844

Query: 784 ITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQP--RNSQ-TDK 840
           +             PL  V +L ++L  D   +++LA E     ++ R+P  RN     +
Sbjct: 845 VIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISR 904

Query: 841 LVNERLISMAYGQIGMIQAL 860
            + + ++  A  Q+ +I  L
Sbjct: 905 TMMKNILGHAVYQLALIFTL 924


>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
           sapiens]
          Length = 1220

 Score =  232 bits (591), Expect = 2e-60
 Identities = 230/802 (28%), Positives = 359/802 (44%), Gaps = 160/802 (19%)

Query: 137 VVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDR 196
           VV+VT    + +E +   +    +    Q+  VIR G+ +Q+    +VVGD+ +VK GD 
Sbjct: 167 VVLVTAFNDWSKEKQFRGLQSRIEQ--EQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDL 224

Query: 197 VPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIV 256
           +PAD  +I ++  K+D SSLTGES+   +S +   ++P+         T+ +EG+ R +V
Sbjct: 225 LPADGVLIQANDLKIDESSLTGESDHVRKSAD---KDPM-----LLSGTHVMEGSGRMVV 276

Query: 257 IATGDRTVMGRIATLA------------------SGLEVGRT-------PIAMEIEHFIQ 291
            A G  +  G I TL                     +E  +T        +AME++    
Sbjct: 277 TAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKS 336

Query: 292 L--------------------------ITGVAVFLGVSFFVLSLIL-------------- 311
                                      +T +AV +G +  V+S I               
Sbjct: 337 AEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFV 396

Query: 312 --GYSWLEA-----VIFLIGIIVANVPEGLLAT---VTVCLTLTAKRMARKNCLVKNL-- 359
             G +WL       V + +   +  V   ++A    + + +T++     +K     NL  
Sbjct: 397 VEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVR 456

Query: 360 --EAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWT 417
             +A ET+G+ + ICSDKTGTLT NRMTV   +               G T  K  P  +
Sbjct: 457 HLDACETMGNATAICSDKTGTLTTNRMTVVQSYL--------------GDTHYKEIPAPS 502

Query: 418 ALS-RIAGLCNRAVF--KAGQENISVSKRDTA-----GDASESALLKCIELSCGSVRKMR 469
           AL+ +I  L   A+    A    I   +++ A     G+ +E ALL  +      +   R
Sbjct: 503 ALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVGNKTECALLGFV------LDLKR 556

Query: 470 DRNPKVAEIP---------FNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILV 520
           D  P   +IP         FNS  K   ++    D      L  KGA E +L +C+ IL 
Sbjct: 557 DFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDG--GFRLFSKGASEILLKKCTNILN 614

Query: 521 QGKEI----PLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFP 576
              E+    P D++  D  +     +   G R +     +  +G+ P     D D  N  
Sbjct: 615 SNGELRGFRPRDRD--DMVRKIIEPMACDGLRTICIAYRDFSAGQEP-----DWDNENEV 667

Query: 577 TEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNE 636
              L  + ++ + DP R  VP+A+ KC+ AGI V MVTGD+  TA+AIA   GII  G +
Sbjct: 668 VGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGED 727

Query: 637 TVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKL 696
                   L +   + N R         ++  ++  E+LD++       V AR+SP  K 
Sbjct: 728 F-------LCLEGKEFNRRIR-------NEKGEIEQERLDKVWPKLR--VLARSSPTDKH 771

Query: 697 IIVEG-----CQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDN 751
            +V+G        Q  +VAVTGDG ND PALKKAD+G AMGI+G+DV+K+A+D+IL DDN
Sbjct: 772 TLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDN 831

Query: 752 FASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGT 811
           F SIV  V  GR ++D++ K + + LT N+  +             PL  V +L ++L  
Sbjct: 832 FTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIM 891

Query: 812 DMVPAISLAYEAAESDIMKRQP 833
           D   +++LA E     ++ R+P
Sbjct: 892 DTFASLALATEPPTESLLLRKP 913


>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
           sapiens]
          Length = 1173

 Score =  232 bits (591), Expect = 2e-60
 Identities = 230/802 (28%), Positives = 359/802 (44%), Gaps = 160/802 (19%)

Query: 137 VVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDR 196
           VV+VT    + +E +   +    +    Q+  VIR G+ +Q+    +VVGD+ +VK GD 
Sbjct: 167 VVLVTAFNDWSKEKQFRGLQSRIEQ--EQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDL 224

Query: 197 VPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIV 256
           +PAD  +I ++  K+D SSLTGES+   +S +   ++P+         T+ +EG+ R +V
Sbjct: 225 LPADGVLIQANDLKIDESSLTGESDHVRKSAD---KDPM-----LLSGTHVMEGSGRMVV 276

Query: 257 IATGDRTVMGRIATLA------------------SGLEVGRT-------PIAMEIEHFIQ 291
            A G  +  G I TL                     +E  +T        +AME++    
Sbjct: 277 TAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKS 336

Query: 292 L--------------------------ITGVAVFLGVSFFVLSLIL-------------- 311
                                      +T +AV +G +  V+S I               
Sbjct: 337 AEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFV 396

Query: 312 --GYSWLEA-----VIFLIGIIVANVPEGLLAT---VTVCLTLTAKRMARKNCLVKNL-- 359
             G +WL       V + +   +  V   ++A    + + +T++     +K     NL  
Sbjct: 397 VEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVR 456

Query: 360 --EAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWT 417
             +A ET+G+ + ICSDKTGTLT NRMTV   +               G T  K  P  +
Sbjct: 457 HLDACETMGNATAICSDKTGTLTTNRMTVVQSYL--------------GDTHYKEIPAPS 502

Query: 418 ALS-RIAGLCNRAVF--KAGQENISVSKRDTA-----GDASESALLKCIELSCGSVRKMR 469
           AL+ +I  L   A+    A    I   +++ A     G+ +E ALL  +      +   R
Sbjct: 503 ALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVGNKTECALLGFV------LDLKR 556

Query: 470 DRNPKVAEIP---------FNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILV 520
           D  P   +IP         FNS  K   ++    D      L  KGA E +L +C+ IL 
Sbjct: 557 DFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDG--GFRLFSKGASEILLKKCTNILN 614

Query: 521 QGKEI----PLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFP 576
              E+    P D++  D  +     +   G R +     +  +G+ P     D D  N  
Sbjct: 615 SNGELRGFRPRDRD--DMVRKIIEPMACDGLRTICIAYRDFSAGQEP-----DWDNENEV 667

Query: 577 TEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNE 636
              L  + ++ + DP R  VP+A+ KC+ AGI V MVTGD+  TA+AIA   GII  G +
Sbjct: 668 VGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGED 727

Query: 637 TVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKL 696
                   L +   + N R         ++  ++  E+LD++       V AR+SP  K 
Sbjct: 728 F-------LCLEGKEFNRRIR-------NEKGEIEQERLDKVWPKLR--VLARSSPTDKH 771

Query: 697 IIVEG-----CQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDN 751
            +V+G        Q  +VAVTGDG ND PALKKAD+G AMGI+G+DV+K+A+D+IL DDN
Sbjct: 772 TLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDN 831

Query: 752 FASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGT 811
           F SIV  V  GR ++D++ K + + LT N+  +             PL  V +L ++L  
Sbjct: 832 FTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIM 891

Query: 812 DMVPAISLAYEAAESDIMKRQP 833
           D   +++LA E     ++ R+P
Sbjct: 892 DTFASLALATEPPTESLLLRKP 913


>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
           sapiens]
          Length = 1176

 Score =  225 bits (573), Expect = 2e-58
 Identities = 183/589 (31%), Positives = 289/589 (49%), Gaps = 74/589 (12%)

Query: 280 TPIAMEIEHFIQLITGVAVFLGVSFFVLSL--ILGYSWLEAV----------IFLIGI-- 325
           T +A++I     L++ + V + V +FV+    +    WL              F+IG+  
Sbjct: 367 TKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTV 426

Query: 326 IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMT 385
           +V  VPEGL   VT+ L  + K+M + N LV++L+A ET+G+ + ICSDKTGTLT NRMT
Sbjct: 427 LVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMT 486

Query: 386 VAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDT 445
           V   +  N+ H     E ++        P       + G+     + +    I   +++ 
Sbjct: 487 VVQAYI-NEKHYKKVPEPEA-------IPPNILSYLVTGISVNCAYTS---KILPPEKEG 535

Query: 446 A-----GDASESALLKCIELSCGSVRKMRDRNPKVA---EIPFNSTNKYQLSIHEREDSP 497
                 G+ +E ALL  +       + +R+  P+ A      FNS  K   ++ +  D  
Sbjct: 536 GLPRHVGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDG- 594

Query: 498 QSHVLVMKGAPERILDRCSTILVQGKEIPL--DKEMQDAFQNAYMELGGLGERVLGFCQL 555
            S+ +  KGA E IL +C  IL    E  +   ++  D  +     +   G R +     
Sbjct: 595 -SYRIFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFR 653

Query: 556 NLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTG 615
           + P+G+ P     + D  N     L  + ++ + DP R  VPDA+ KC+ AGI V MVTG
Sbjct: 654 DFPAGE-PEP---EWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTG 709

Query: 616 DHPITAKAIAKGVGIISEGNETV----EDIAARLNIPMSQVNPREAKACVVHGSDLKDMT 671
           D+  TA+AIA   GI+  G + +    +D   R+                   ++  ++ 
Sbjct: 710 DNINTARAIATKCGILHPGEDFLCLEGKDFNRRIR------------------NEKGEIE 751

Query: 672 SEQLDEILKNHTEIVFARTSPQQKLIIVEGC-------QRQGAIVAVTGDGVNDSPALKK 724
            E++D+I       V AR+SP  K  +V+G        QRQ  +VAVTGDG ND PALKK
Sbjct: 752 QERIDKIWPKLR--VLARSSPTDKHTLVKGIIDSTVSDQRQ--VVAVTGDGTNDGPALKK 807

Query: 725 ADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEI 784
           AD+G AMGI+G+DV+K+A+D+IL DDNF SIV  V  GR ++D++ K + + LT N+  +
Sbjct: 808 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV 867

Query: 785 TPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQP 833
                        PL  V +L ++L  D + +++LA E     ++ R+P
Sbjct: 868 IVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKP 916



 Score = 67.4 bits (163), Expect = 7e-11
 Identities = 45/138 (32%), Positives = 72/138 (52%), Gaps = 10/138 (7%)

Query: 134 LAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKG 193
           +  VV+VT    + +E +   +    +    Q+  VIR G+ +QI   ++ VGD+ +VK 
Sbjct: 163 VVCVVLVTAFNDWSKEKQFRGLQSRIEQ--EQKFTVIRGGQVIQIPVADITVGDIAQVKY 220

Query: 194 GDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTAR 253
           GD +PAD  +I  +  K+D SSLTGES+   +S        L+   +    T+ +EG+ R
Sbjct: 221 GDLLPADGILIQGNDLKIDESSLTGESDHVKKS--------LDKDPLLLSGTHVMEGSGR 272

Query: 254 GIVIATGDRTVMGRIATL 271
            +V A G  +  G I TL
Sbjct: 273 MVVTAVGVNSQTGIIFTL 290


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,670,480
Number of Sequences: 37866
Number of extensions: 1598019
Number of successful extensions: 4602
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 4239
Number of HSP's gapped (non-prelim): 179
length of query: 1020
length of database: 18,247,518
effective HSP length: 112
effective length of query: 908
effective length of database: 14,006,526
effective search space: 12717925608
effective search space used: 12717925608
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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