BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] (1020 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] 2026 0.0 gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] 1789 0.0 gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] 1786 0.0 gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi... 1782 0.0 gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi... 1768 0.0 gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi... 1632 0.0 gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 1321 0.0 gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens] 1320 0.0 gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 377 e-104 gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 377 e-104 gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom... 377 e-104 gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom... 377 e-104 gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom... 377 e-104 gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom... 377 e-104 gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom... 377 e-104 gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap... 375 e-104 gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap... 375 e-104 gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap... 375 e-104 gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap... 375 e-104 gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H... 370 e-102 gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [... 370 e-102 gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ... 361 2e-99 gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [... 360 3e-99 gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [... 360 4e-99 gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ... 341 2e-93 gi|49249977 Na+/K+ -ATPase alpha 4 subunit isoform 2 [Homo sapiens] 289 8e-78 gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 258 2e-68 gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 232 2e-60 gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa... 232 2e-60 gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 225 2e-58 >gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] Length = 1020 Score = 2026 bits (5249), Expect = 0.0 Identities = 1020/1020 (100%), Positives = 1020/1020 (100%) Query: 1 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKG 60 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKG Sbjct: 1 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKG 60 Query: 61 LTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAME 120 LTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAME Sbjct: 61 LTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAME 120 Query: 121 DEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINA 180 DEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINA Sbjct: 121 DEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINA 180 Query: 181 EEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNI 240 EEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNI Sbjct: 181 EEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNI 240 Query: 241 CFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFL 300 CFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFL Sbjct: 241 CFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFL 300 Query: 301 GVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLE 360 GVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLE Sbjct: 301 GVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLE 360 Query: 361 AVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALS 420 AVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALS Sbjct: 361 AVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALS 420 Query: 421 RIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPF 480 RIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPF Sbjct: 421 RIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPF 480 Query: 481 NSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYM 540 NSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYM Sbjct: 481 NSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYM 540 Query: 541 ELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAV 600 ELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAV Sbjct: 541 ELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAV 600 Query: 601 GKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKAC 660 GKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKAC Sbjct: 601 GKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKAC 660 Query: 661 VVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSP 720 VVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSP Sbjct: 661 VVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSP 720 Query: 721 ALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSN 780 ALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSN Sbjct: 721 ALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSN 780 Query: 781 IPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDK 840 IPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDK Sbjct: 781 IPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDK 840 Query: 841 LVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYG 900 LVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYG Sbjct: 841 LVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYG 900 Query: 901 QEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETA 960 QEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETA Sbjct: 901 QEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETA 960 Query: 961 LAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 1020 LAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY Sbjct: 961 LAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 1020 >gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] Length = 1023 Score = 1789 bits (4634), Expect = 0.0 Identities = 888/1023 (86%), Positives = 960/1023 (93%), Gaps = 3/1023 (0%) Query: 1 MGRGAGRE-YSPAATTAENGG-GKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLS 58 MG+G GR+ Y PAA + + GKK +K++++DELKKEV+MDDHKLSLDEL RKY DLS Sbjct: 1 MGKGVGRDKYEPAAVSEQGDKKGKKGKKDRDMDELKKEVSMDDHKLSLDELHRKYGTDLS 60 Query: 59 KGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAA 118 +GLT+ RA ++LARDGPNALTPPPTTPEW+KFCRQLFGGFS+LLWIGAILCFLAY IQAA Sbjct: 61 RGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSMLLWIGAILCFLAYSIQAA 120 Query: 119 MEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQI 178 E+EP NDNLYLGVVL+AVVI+TGCFSYYQEAKSSKIM+SFKNMVPQQALVIR GEKM I Sbjct: 121 TEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSI 180 Query: 179 NAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETR 238 NAEEVVVGDLVEVKGGDR+PADLRIIS++GCKVDNSSLTGESEPQTRSP+FT+ENPLETR Sbjct: 181 NAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETR 240 Query: 239 NICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAV 298 NI FFSTNCVEGTARGIV+ TGDRTVMGRIATLASGLE G+TPIA EIEHFI +ITGVAV Sbjct: 241 NIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAV 300 Query: 299 FLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKN 358 FLGVSFF+LSLIL Y+WLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKN Sbjct: 301 FLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKN 360 Query: 359 LEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTA 418 LEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTE+QSG +FDK S TW A Sbjct: 361 LEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLA 420 Query: 419 LSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEI 478 LSRIAGLCNRAVF+A QEN+ + KR AGDASESALLKCIEL CGSV++MR+R K+ EI Sbjct: 421 LSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIVEI 480 Query: 479 PFNSTNKYQLSIHEREDSPQ-SHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQN 537 PFNSTNKYQLSIH+ ++ + H+LVMKGAPERILDRCS+IL+ GKE PLD+E++DAFQN Sbjct: 481 PFNSTNKYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQN 540 Query: 538 AYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVP 597 AY+ELGGLGERVLGFC L LP +FP GF+FDTD++NFP + LCFVGL+SMIDPPRAAVP Sbjct: 541 AYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVP 600 Query: 598 DAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREA 657 DAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIP+SQVNPR+A Sbjct: 601 DAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDA 660 Query: 658 KACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVN 717 KACVVHGSDLKDMTSEQLD+ILK HTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVN Sbjct: 661 KACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVN 720 Query: 718 DSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTL 777 DSPALKKADIG+AMGI+GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTL Sbjct: 721 DSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTL 780 Query: 778 TSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQ 837 TSNIPEITPFL+FIIANIPLPLGTVTILCIDLGTDMVPAISLAYE AESDIMKRQPRN + Sbjct: 781 TSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPK 840 Query: 838 TDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLED 897 TDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLP LLG+R+DWDDR +ND+ED Sbjct: 841 TDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPIHLLGLRVDWDDRWINDVED 900 Query: 898 SYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLE 957 SYGQ+WTYEQRK+VEFTCHTAFF SIVVVQWADL+ICKTRRNSVFQQGMKNKILIFGL E Sbjct: 901 SYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFE 960 Query: 958 ETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKE 1017 ETALAAFLSYCPGMGVALRMYPLK TWWFCAFPYSLLIF+YDEVRKLI+RR PGGWVEKE Sbjct: 961 ETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKE 1020 Query: 1018 TYY 1020 TYY Sbjct: 1021 TYY 1023 >gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] Length = 1013 Score = 1786 bits (4625), Expect = 0.0 Identities = 885/1001 (88%), Positives = 949/1001 (94%), Gaps = 2/1001 (0%) Query: 22 KKKQKEK-ELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTP 80 K K KE+ +LD+LKKEVAM +HK+S++E+ RKY D +GLT+ +AQ++LARDGPNALTP Sbjct: 13 KNKGKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTP 72 Query: 81 PPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIV 140 PPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQA ED+PS DNLYLG+VLAAVVI+ Sbjct: 73 PPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVII 132 Query: 141 TGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPAD 200 TGCFSYYQEAKSSKIM+SFKNMVPQQALVIREGEKMQ+NAEEVVVGDLVE+KGGDRVPAD Sbjct: 133 TGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPAD 192 Query: 201 LRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATG 260 LRIIS+HGCKVDNSSLTGESEPQTRSP+ TH+NPLETRNI FFSTNCVEGTARG+V+ATG Sbjct: 193 LRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATG 252 Query: 261 DRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVI 320 DRTVMGRIATLASGLEVG+TPIA+EIEHFIQLITGVAVFLGVSFF+LSLILGY+WLEAVI Sbjct: 253 DRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVI 312 Query: 321 FLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLT 380 FLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLT Sbjct: 313 FLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLT 372 Query: 381 QNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISV 440 QNRMTVAHMWFDNQIHEADTTEDQSG +FDK S TW ALS IAGLCNRAVFK GQ+NI V Sbjct: 373 QNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPV 432 Query: 441 SKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHERED-SPQS 499 KRD AGDASESALLKCIELS GSV+ MR+RN KVAEIPFNSTNKYQLSIHE ED + Sbjct: 433 LKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQLSIHETEDPNDNR 492 Query: 500 HVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPS 559 ++LVMKGAPERILDRCSTIL+QGKE PLD+EM++AFQNAY+ELGGLGERVLGFC LP Sbjct: 493 YLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPE 552 Query: 560 GKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPI 619 +FP+GF FD D++NF T+ LCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPI Sbjct: 553 EQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPI 612 Query: 620 TAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEIL 679 TAKAIAKGVGIISEGNETVEDIAARLNIP+SQVNPR+AKACV+HG+DLKD TSEQ+DEIL Sbjct: 613 TAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEIL 672 Query: 680 KNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVS 739 +NHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIG+AMGI+GSDVS Sbjct: 673 QNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVS 732 Query: 740 KQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPL 799 KQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFI+ANIPLPL Sbjct: 733 KQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPL 792 Query: 800 GTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQA 859 GT+TILCIDLGTDMVPAISLAYEAAESDIMKRQPRN +TDKLVNERLISMAYGQIGMIQA Sbjct: 793 GTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQA 852 Query: 860 LGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAF 919 LGGFF+YFVILAENGFLP L+GIRL+WDDRT+NDLEDSYGQ+WTYEQRKVVEFTCHTAF Sbjct: 853 LGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEFTCHTAF 912 Query: 920 FASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYP 979 F SIVVVQWADLIICKTRRNSVFQQGMKNKILIFGL EETALAAFLSYCPGM VALRMYP Sbjct: 913 FVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYP 972 Query: 980 LKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 1020 LK +WWFCAFPYS LIF+YDE+RKLILRR PGGWVEKETYY Sbjct: 973 LKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY 1013 >gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapiens] Length = 1023 Score = 1782 bits (4615), Expect = 0.0 Identities = 883/1015 (86%), Positives = 954/1015 (93%), Gaps = 2/1015 (0%) Query: 8 EYSPAATTAENGG-GKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRA 66 +Y PAA + + GKK +K++++DELKKEV+MDDHKLSLDEL RKY DLS+GLT+ RA Sbjct: 9 KYEPAAVSEQGDKKGKKGKKDRDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARA 68 Query: 67 QDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSND 126 ++LARDGPNALTPPPTTPEW+KFCRQLFGGFS+LLWIGAILCFLAY IQAA E+EP ND Sbjct: 69 AEILARDGPNALTPPPTTPEWIKFCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQND 128 Query: 127 NLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVG 186 NLYLGVVL+AVVI+TGCFSYYQEAKSSKIM+SFKNMVPQQALVIR GEKM INAEEVVVG Sbjct: 129 NLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVG 188 Query: 187 DLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTN 246 DLVEVKGGDR+PADLRIIS++GCKVDNSSLTGESEPQTRSP+FT+ENPLETRNI FFSTN Sbjct: 189 DLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTN 248 Query: 247 CVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFV 306 CVEGTARGIV+ TGDRTVMGRIATLASGLE G+TPIA EIEHFI +ITGVAVFLGVSFF+ Sbjct: 249 CVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFI 308 Query: 307 LSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLG 366 LSLIL Y+WLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLG Sbjct: 309 LSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLG 368 Query: 367 STSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLC 426 STSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTE+QSG +FDK S TW ALSRIAGLC Sbjct: 369 STSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLC 428 Query: 427 NRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKY 486 NRAVF+A QEN+ + KR AGDASESALLKCIEL CGSV++MR+R K+ EIPFNSTNKY Sbjct: 429 NRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKY 488 Query: 487 QLSIHEREDSPQ-SHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGL 545 QLSIH+ ++ + H+LVMKGAPERILDRCS+IL+ GKE PLD+E++DAFQNAY+ELGGL Sbjct: 489 QLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGL 548 Query: 546 GERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRS 605 GERVLGFC L LP +FP GF+FDTD++NFP + LCFVGL+SMIDPPRAAVPDAVGKCRS Sbjct: 549 GERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRS 608 Query: 606 AGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGS 665 AGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIP+SQVNPR+AKACVVHGS Sbjct: 609 AGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGS 668 Query: 666 DLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKA 725 DLKDMTSEQLD+ILK HTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKA Sbjct: 669 DLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKA 728 Query: 726 DIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEIT 785 DIG+AMGI+GSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEIT Sbjct: 729 DIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEIT 788 Query: 786 PFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNER 845 PFL+FIIANIPLPLGTVTILCIDLGTDMVPAISLAYE AESDIMKRQPRN +TDKLVNER Sbjct: 789 PFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNER 848 Query: 846 LISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTY 905 LISMAYGQIGMIQALGGFFTYFVILAENGFLP LLG+R+DWDDR +ND+EDSYGQ+WTY Sbjct: 849 LISMAYGQIGMIQALGGFFTYFVILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTY 908 Query: 906 EQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFL 965 EQRK+VEFTCHTAFF SIVVVQWADL+ICKTRRNSVFQQGMKNKILIFGL EETALAAFL Sbjct: 909 EQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFL 968 Query: 966 SYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 1020 SYCPGMGVALRMYPLK TWWFCAFPYSLLIF+YDEVRKLI+RR PGGWVEKETYY Sbjct: 969 SYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 1023 >gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapiens] Length = 992 Score = 1768 bits (4579), Expect = 0.0 Identities = 875/992 (88%), Positives = 939/992 (94%), Gaps = 1/992 (0%) Query: 30 LDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVK 89 +DELKKEV+MDDHKLSLDEL RKY DLS+GLT+ RA ++LARDGPNALTPPPTTPEW+K Sbjct: 1 MDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIK 60 Query: 90 FCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQE 149 FCRQLFGGFS+LLWIGAILCFLAY IQAA E+EP NDNLYLGVVL+AVVI+TGCFSYYQE Sbjct: 61 FCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQE 120 Query: 150 AKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGC 209 AKSSKIM+SFKNMVPQQALVIR GEKM INAEEVVVGDLVEVKGGDR+PADLRIIS++GC Sbjct: 121 AKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGC 180 Query: 210 KVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIA 269 KVDNSSLTGESEPQTRSP+FT+ENPLETRNI FFSTNCVEGTARGIV+ TGDRTVMGRIA Sbjct: 181 KVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIA 240 Query: 270 TLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVAN 329 TLASGLE G+TPIA EIEHFI +ITGVAVFLGVSFF+LSLIL Y+WLEAVIFLIGIIVAN Sbjct: 241 TLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVAN 300 Query: 330 VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 389 VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM Sbjct: 301 VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 360 Query: 390 WFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDA 449 WFDNQIHEADTTE+QSG +FDK S TW ALSRIAGLCNRAVF+A QEN+ + KR AGDA Sbjct: 361 WFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDA 420 Query: 450 SESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQ-SHVLVMKGAP 508 SESALLKCIEL CGSV++MR+R K+ EIPFNSTNKYQLSIH+ ++ + H+LVMKGAP Sbjct: 421 SESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAP 480 Query: 509 ERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKF 568 ERILDRCS+IL+ GKE PLD+E++DAFQNAY+ELGGLGERVLGFC L LP +FP GF+F Sbjct: 481 ERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQF 540 Query: 569 DTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV 628 DTD++NFP + LCFVGL+SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV Sbjct: 541 DTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV 600 Query: 629 GIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFA 688 GIISEGNETVEDIAARLNIP+SQVNPR+AKACVVHGSDLKDMTSEQLD+ILK HTEIVFA Sbjct: 601 GIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFA 660 Query: 689 RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILL 748 RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIG+AMGI+GSDVSKQAADMILL Sbjct: 661 RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 720 Query: 749 DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCID 808 DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFL+FIIANIPLPLGTVTILCID Sbjct: 721 DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCID 780 Query: 809 LGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFV 868 LGTDMVPAISLAYE AESDIMKRQPRN +TDKLVNERLISMAYGQIGMIQALGGFFTYFV Sbjct: 781 LGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFV 840 Query: 869 ILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQW 928 ILAENGFLP LLG+R+DWDDR +ND+EDSYGQ+WTYEQRK+VEFTCHTAFF SIVVVQW Sbjct: 841 ILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQW 900 Query: 929 ADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCA 988 ADL+ICKTRRNSVFQQGMKNKILIFGL EETALAAFLSYCPGMGVALRMYPLK TWWFCA Sbjct: 901 ADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCA 960 Query: 989 FPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 1020 FPYSLLIF+YDEVRKLI+RR PGGWVEKETYY Sbjct: 961 FPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 992 >gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapiens] Length = 1029 Score = 1632 bits (4225), Expect = 0.0 Identities = 804/999 (80%), Positives = 902/999 (90%), Gaps = 1/999 (0%) Query: 22 KKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPP 81 K++++++ ++ELKKEV MDDHKL+L+EL KY VDL+KG ++QRA+++L R GPN +TPP Sbjct: 32 KREKQKRNMEELKKEVVMDDHKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPP 91 Query: 82 PTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVT 141 PTTPEWVKFC+QLFGGFS+LLW GAILCF+AY IQ +EP+ DNLYL +VL+ VVIVT Sbjct: 92 PTTPEWVKFCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVT 151 Query: 142 GCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADL 201 GCFSYYQEAKSSKIM+SFKNMVPQQALVIR GEKMQIN +EVV+GDLVE+KGGDRVPADL Sbjct: 152 GCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADL 211 Query: 202 RIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGD 261 R+IS+ GCKVDNSSLTGESEPQ+RSP+FTHENPLETRNICFFSTNCVEGTARGIVIATGD Sbjct: 212 RLISAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVEGTARGIVIATGD 271 Query: 262 RTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIF 321 TVMGRIA+L SGL VG+TPIA EIEHFI LIT VAVFLGV+FF LSL+LGY WLEA+IF Sbjct: 272 STVMGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAIIF 331 Query: 322 LIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQ 381 LIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQ Sbjct: 332 LIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQ 391 Query: 382 NRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVS 441 NRMTVAHMWFD ++EADTTE+Q+G TF K S TW L+RIAGLCNRA FKA QE + ++ Sbjct: 392 NRMTVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEILPIA 451 Query: 442 KRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHV 501 KR T GDASESALLK IE S SV +MR++NPKVAEIPFNSTNKYQ+SIH REDS Q+HV Sbjct: 452 KRATTGDASESALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQMSIHLREDSSQTHV 511 Query: 502 LVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGK 561 L+MKGAPERIL+ CST L+ G+E ++ EM++AFQNAY+ELGGLGERVLGFC LNLPS Sbjct: 512 LMMKGAPERILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNLPS-S 570 Query: 562 FPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITA 621 F +GF F+TDE+NFP + LCFVGL+SMIDPPRAAVPDAV KCRSAGIKVIMVTGDHPITA Sbjct: 571 FSKGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITA 630 Query: 622 KAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKN 681 KAIAKGVGIISEG ET E++AARL IP+S+V+ AKA VVHG++LKD+ S+QLD+IL+N Sbjct: 631 KAIAKGVGIISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQN 690 Query: 682 HTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQ 741 H EIVFARTSPQQKLIIVEGCQR GA+VAVTGDGVNDSPALKKADIGIAMGISGSDVSKQ Sbjct: 691 HPEIVFARTSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQ 750 Query: 742 AADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGT 801 AADMILLDDNFASIVTGVEEGRLIFDNLKKSI YTLTSNIPEITPFL+FII IPLPLGT Sbjct: 751 AADMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGT 810 Query: 802 VTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALG 861 +TILCIDLGTDMVPAISLAYE+AESDIMKR PRN +TD LVN RLI MAYGQIGMIQAL Sbjct: 811 ITILCIDLGTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALA 870 Query: 862 GFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFA 921 GFFTYFVILAENGF P LLGIRL W+D+ +NDLEDSYGQ+WTYEQRKVVEFTC TAFF Sbjct: 871 GFFTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFV 930 Query: 922 SIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLK 981 +IVVVQWADLII KTRRNS+FQQGM+NK+LIFG+LEET LAAFLSY PGM VALRMYPLK Sbjct: 931 TIVVVQWADLIISKTRRNSLFQQGMRNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLK 990 Query: 982 VTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 1020 +TWW CA PYS+LIF+YDE+RKL++R++P GWVE+ETYY Sbjct: 991 ITWWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY 1029 >gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] Length = 1039 Score = 1321 bits (3420), Expect = 0.0 Identities = 659/1017 (64%), Positives = 809/1017 (79%), Gaps = 13/1017 (1%) Query: 17 ENGGGKKK-----------QKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQR 65 + G GK+K +K+ +E +KE+ +DDHKLS EL KY D+ GL++ R Sbjct: 23 DKGDGKEKYRGLKNNCLELKKKNHKEEFQKELHLDDHKLSNRELEEKYGTDIIMGLSSTR 82 Query: 66 AQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSN 125 A ++LARDGPN+LTPP TPE VKF +Q+ GGFSILLW+GA LC++AYGIQ + + S Sbjct: 83 AAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILLWVGAFLCWIAYGIQYSSDKSASL 142 Query: 126 DNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVV 185 +N+YLG VL VVI+TG F+YYQEAKS+ IM SF M+PQQALVIR+ EK I +E++VV Sbjct: 143 NNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVV 202 Query: 186 GDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFST 245 GD+VEVKGGD++PAD+R++SS GC+VDNSSLTGESEPQ RS EFTHENPLET+NICF+ST Sbjct: 203 GDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFYST 262 Query: 246 NCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFF 305 C+EGT G+VI TGDRT++G IA+LASG+ +TPIA+EIEHF+ ++ GVAV +G+ FF Sbjct: 263 TCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEHFVHIVAGVAVSIGILFF 322 Query: 306 VLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETL 365 ++++ L Y L+++IFLIGIIVANVPEGLLATVTV L+LTAKRMA+KNCLVKNLEAVETL Sbjct: 323 IIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETL 382 Query: 366 GSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGL 425 GSTS ICSDKTGTLTQNRMTVAH+WFDNQI ADT+ED S FD+ S TW +LS+I L Sbjct: 383 GSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWASLSKIITL 442 Query: 426 CNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNK 485 CNRA FK GQEN+ + K+ GDASE+ALLK E+ G V ++R RN KVAEIPFNSTNK Sbjct: 443 CNRAEFKPGQENVPIMKKAVIGDASETALLKFSEVILGDVMEIRKRNRKVAEIPFNSTNK 502 Query: 486 YQLSIHEREDSP-QSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGG 544 +QLSIHE +D + ++VMKGAPERIL++CSTI++ G+E PLDK F AYMELGG Sbjct: 503 FQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMINGEEHPLDKSTAKTFHTAYMELGG 562 Query: 545 LGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCR 604 LGERVLGFC L LP+ +FP + FD D +NFPT LCFVGL+SMIDPPR+ VPDAV KCR Sbjct: 563 LGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCR 622 Query: 605 SAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHG 664 SAGIKVIMVTGDHPITAKAIAK VGIIS +ETVEDIA RLNI + QVN R+AKA VV G Sbjct: 623 SAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAKAAVVTG 682 Query: 665 SDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKK 724 +LKDM+SEQLDEIL N+ EIVFARTSPQQKLIIVEGCQRQ A+VAVTGDGVNDSPALKK Sbjct: 683 MELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKK 742 Query: 725 ADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEI 784 ADIGIAMGI+GSD +K AADM+LLDDNFASIVTGVEEGRLIFDNLKK+IAY+LT NI E+ Sbjct: 743 ADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIAEL 802 Query: 785 TPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNE 844 PFL++II +PLP+GT+TIL IDLGTD++P+I+LAYE AESDIM R+PR+ D+LVN+ Sbjct: 803 CPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQ 862 Query: 845 RLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWT 904 L +Y IG++QALG F YF + A+ GFLP L+ +R++W+ +NDL+DSYGQEWT Sbjct: 863 PLAVYSYLHIGLMQALGAFLVYFTVYAQEGFLPRTLINLRVEWEKDYVNDLKDSYGQEWT 922 Query: 905 YEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGM-KNKILIFGLLEETALAA 963 QR+ +E+T +TAFF I+V Q ADLII KTRRNS+FQQG+ +NK++ G+ + + Sbjct: 923 RYQREYLEWTGYTAFFVGILVQQIADLIIRKTRRNSIFQQGLFRNKVIWVGITSQIIIGL 982 Query: 964 FLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 1020 LSY G AL L+ +WF A P+++LI++YDEVRKL +R YPG W +K YY Sbjct: 983 ILSYGLGSVTALSFTMLRAQYWFVAVPHAILIWVYDEVRKLFIRLYPGSWWDKNMYY 1039 >gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens] Length = 1035 Score = 1320 bits (3417), Expect = 0.0 Identities = 640/1022 (62%), Positives = 809/1022 (79%), Gaps = 2/1022 (0%) Query: 1 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKG 60 +G G G + + + + GG +++++L+ +KKE+ ++DH+LS+ EL +KYQ +KG Sbjct: 14 LGPGPGGDMAAKMSKKKKAGGGGGKRKEKLENMKKEMEINDHQLSVAELEQKYQTSATKG 73 Query: 61 LTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAME 120 L+ A ++L RDGPNAL PP TPE+VKF RQL GG L+W+ A +C +A+ IQA+ Sbjct: 74 LSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICLIAFAIQASEG 133 Query: 121 DEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINA 180 D ++DNLYL + L AVV+VTGCF YYQE KS+ I+ SFKN+VPQQA VIR+G+K QINA Sbjct: 134 DLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINA 193 Query: 181 EEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNI 240 +++VVGDLVE+KGGDRVPAD+RI+++ GCKVDNSSLTGESEPQTRSPE THE+PLETRNI Sbjct: 194 DQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNI 253 Query: 241 CFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFL 300 FFST C+EGT +G+V+ TGDRT++GRIA+LASG+E +TPIA+EIEHF+ +I G+A+ Sbjct: 254 AFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIEHFVDIIAGLAILF 313 Query: 301 GVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLE 360 G +FF++++ +GY++L A++F + I+VA VPEGLLATVTVCL+LTAKR+A KNC+VKNLE Sbjct: 314 GATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLE 373 Query: 361 AVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALS 420 AVETLGSTS ICSDKTGTLTQNRMTV+H+WFDN IH ADTTEDQSG TFD+ S TW AL Sbjct: 374 AVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALC 433 Query: 421 RIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPF 480 R+ LCNRA FK+GQ+ + V KR GDASE+ALLK EL+ G+ RDR PKV EIPF Sbjct: 434 RVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPF 493 Query: 481 NSTNKYQLSIHERED-SPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAY 539 NSTNK+QLSIH ED H+LVMKGAPER+L+RCS+IL++G+E+PLD++ ++AFQ AY Sbjct: 494 NSTNKFQLSIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPLDEQWREAFQTAY 553 Query: 540 MELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDA 599 + LGGLGERVLGFCQL L +P G+ FD + +NFP+ LCF GL+SMIDPPRA VPDA Sbjct: 554 LSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDA 613 Query: 600 VGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKA 659 V KCR+AGI+VIMVTGDHPITAKAIA VGIISEG+ETVEDIAARL +P+ QVN ++A+A Sbjct: 614 VLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVPVDQVNRKDARA 673 Query: 660 CVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDS 719 CV++G LKDM +L E L+ H E+VFARTSPQQKL+IVE CQR GAIVAVTGDGVNDS Sbjct: 674 CVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAIVAVTGDGVNDS 733 Query: 720 PALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTS 779 PALKKADIG+AMGI+GSD +K AADMILLDDNFASIVTGVE+GRLIFDNLKKSIAYTLT Sbjct: 734 PALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTK 793 Query: 780 NIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTD 839 NIPE+TP+L++I ++PLPLG +TIL I+L TD+ P++SLAYE AESDIM +PRN + D Sbjct: 794 NIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRPRNPKRD 853 Query: 840 KLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSY 899 +LVNE L + +Y QIG IQ+ GF YF +A+ G+ P +G+R W+D + DL+DSY Sbjct: 854 RLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQWEDHHLQDLQDSY 913 Query: 900 GQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQG-MKNKILIFGLLEE 958 GQEWT+ QR ++TC+T FF SI V Q AD++I KTRR S FQQG +NKIL+ ++ + Sbjct: 914 GQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGFFRNKILVIAIVFQ 973 Query: 959 TALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKET 1018 + FL YCPGM P++ WW PY +LIF+YDE+RKL +R PG W ++E Sbjct: 974 VCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLGVRCCPGSWWDQEL 1033 Query: 1019 YY 1020 YY Sbjct: 1034 YY 1035 >gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo sapiens] Length = 1029 Score = 377 bits (968), Expect = e-104 Identities = 307/1034 (29%), Positives = 483/1034 (46%), Gaps = 103/1034 (9%) Query: 42 HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 101 H L ++ R + V GL+ + R GPN L W Q + Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64 Query: 102 LWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKN 161 L + A++ F+ + E E + +V+ +++ +QE + +++ K Sbjct: 65 LLLAALVSFVLAWFE---EGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121 Query: 162 MVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRIIS--SHGCKVDNSSLT 217 P+ VIR K +I A ++V GD+VEV GD+VPADLR+I S +VD S LT Sbjct: 122 YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181 Query: 218 GESEPQTRSPEFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASG 274 GES T+ E + + +N+ F TN G A G+ +ATG T +G+I + + Sbjct: 182 GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241 Query: 275 LEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IG 324 +E RTP+ +++ F + ++ + V+ +V+++ G SWL ++ + Sbjct: 242 VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301 Query: 325 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 384 + VA +PEGL A +T CL L +RMARKN +V++L +VETLG TS ICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 385 TVAHMWFDNQ-------IHE---ADTTEDQSGATFDKRSPT----WTALSRIAGLCNRAV 430 +V M+ + +HE + TT G P + L +A +C Sbjct: 362 SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421 Query: 431 FKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRN 472 A N + + G+A+E+AL +E +C +V K R Sbjct: 422 DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRK 481 Query: 473 PKVAEIPFNSTNKYQLSIHEREDSP----QSHVLVMKGAPERILDRCSTILVQGKEIPLD 528 E S ++ +S++ P Q + +KGAPE +++RCS++ V + PL Sbjct: 482 EFTLEF---SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLT 538 Query: 529 KEMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLM 586 ++ + G + R L + P K + + + T+ L FVG + Sbjct: 539 PTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETD-LTFVGCV 597 Query: 587 SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLN 646 M+DPPR V + +C AGI+V+M+TGD+ TA AI + +GI + ED+A + Sbjct: 598 GMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVAGK-- 651 Query: 647 IPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQG 706 G + D++ EQ + + T FAR P K IVE Q Sbjct: 652 --------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHKSRIVENLQSFN 695 Query: 707 AIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIF 766 I A+TGDGVND+PALKKA+IGIAMG SG+ V+K AA+M+L DDNFASIV VEEGR I+ Sbjct: 696 EITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIY 754 Query: 767 DNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAES 826 N+K+ I Y ++SN+ E+ L I +P L V +L ++L TD +PA +L + + Sbjct: 755 SNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDL 814 Query: 827 DIMKRQPRNSQTDKLVNERLI--SMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIR 884 DIM++ PR S + L++ L +A G + + +FV AE + L Sbjct: 815 DIMEKLPR-SPREALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNF 873 Query: 885 LDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQ 944 L + N L E +E R T + +V ++ + + + S+ + Sbjct: 874 LKCSED--NPLFAGIDCE-VFESRFPT-----TMALSVLVTIEMCNALNSVSENQSLLRM 925 Query: 945 -GMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRK 1003 N L+ + AL + P + + ++ PL W SL + + DE K Sbjct: 926 PPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVILLDEALK 985 Query: 1004 LILRR------YPG 1011 + R YPG Sbjct: 986 YLSRNHMHACLYPG 999 >gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo sapiens] Length = 1029 Score = 377 bits (968), Expect = e-104 Identities = 307/1034 (29%), Positives = 483/1034 (46%), Gaps = 103/1034 (9%) Query: 42 HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 101 H L ++ R + V GL+ + R GPN L W Q + Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64 Query: 102 LWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKN 161 L + A++ F+ + E E + +V+ +++ +QE + +++ K Sbjct: 65 LLLAALVSFVLAWFE---EGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121 Query: 162 MVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRIIS--SHGCKVDNSSLT 217 P+ VIR K +I A ++V GD+VEV GD+VPADLR+I S +VD S LT Sbjct: 122 YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181 Query: 218 GESEPQTRSPEFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASG 274 GES T+ E + + +N+ F TN G A G+ +ATG T +G+I + + Sbjct: 182 GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241 Query: 275 LEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IG 324 +E RTP+ +++ F + ++ + V+ +V+++ G SWL ++ + Sbjct: 242 VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301 Query: 325 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 384 + VA +PEGL A +T CL L +RMARKN +V++L +VETLG TS ICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 385 TVAHMWFDNQ-------IHE---ADTTEDQSGATFDKRSPT----WTALSRIAGLCNRAV 430 +V M+ + +HE + TT G P + L +A +C Sbjct: 362 SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421 Query: 431 FKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRN 472 A N + + G+A+E+AL +E +C +V K R Sbjct: 422 DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRK 481 Query: 473 PKVAEIPFNSTNKYQLSIHEREDSP----QSHVLVMKGAPERILDRCSTILVQGKEIPLD 528 E S ++ +S++ P Q + +KGAPE +++RCS++ V + PL Sbjct: 482 EFTLEF---SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLT 538 Query: 529 KEMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLM 586 ++ + G + R L + P K + + + T+ L FVG + Sbjct: 539 PTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETD-LTFVGCV 597 Query: 587 SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLN 646 M+DPPR V + +C AGI+V+M+TGD+ TA AI + +GI + ED+A + Sbjct: 598 GMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVAGK-- 651 Query: 647 IPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQG 706 G + D++ EQ + + T FAR P K IVE Q Sbjct: 652 --------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHKSRIVENLQSFN 695 Query: 707 AIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIF 766 I A+TGDGVND+PALKKA+IGIAMG SG+ V+K AA+M+L DDNFASIV VEEGR I+ Sbjct: 696 EITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIY 754 Query: 767 DNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAES 826 N+K+ I Y ++SN+ E+ L I +P L V +L ++L TD +PA +L + + Sbjct: 755 SNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDL 814 Query: 827 DIMKRQPRNSQTDKLVNERLI--SMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIR 884 DIM++ PR S + L++ L +A G + + +FV AE + L Sbjct: 815 DIMEKLPR-SPREALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNF 873 Query: 885 LDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQ 944 L + N L E +E R T + +V ++ + + + S+ + Sbjct: 874 LKCSED--NPLFAGIDCE-VFESRFPT-----TMALSVLVTIEMCNALNSVSENQSLLRM 925 Query: 945 -GMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRK 1003 N L+ + AL + P + + ++ PL W SL + + DE K Sbjct: 926 PPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVILLDEALK 985 Query: 1004 LILRR------YPG 1011 + R YPG Sbjct: 986 YLSRNHMHACLYPG 999 >gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo sapiens] Length = 1043 Score = 377 bits (968), Expect = e-104 Identities = 307/1034 (29%), Positives = 483/1034 (46%), Gaps = 103/1034 (9%) Query: 42 HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 101 H L ++ R + V GL+ + R GPN L W Q + Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64 Query: 102 LWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKN 161 L + A++ F+ + E E + +V+ +++ +QE + +++ K Sbjct: 65 LLLAALVSFVLAWFE---EGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121 Query: 162 MVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRIIS--SHGCKVDNSSLT 217 P+ VIR K +I A ++V GD+VEV GD+VPADLR+I S +VD S LT Sbjct: 122 YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181 Query: 218 GESEPQTRSPEFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASG 274 GES T+ E + + +N+ F TN G A G+ +ATG T +G+I + + Sbjct: 182 GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241 Query: 275 LEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IG 324 +E RTP+ +++ F + ++ + V+ +V+++ G SWL ++ + Sbjct: 242 VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301 Query: 325 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 384 + VA +PEGL A +T CL L +RMARKN +V++L +VETLG TS ICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 385 TVAHMWFDNQ-------IHE---ADTTEDQSGATFDKRSPT----WTALSRIAGLCNRAV 430 +V M+ + +HE + TT G P + L +A +C Sbjct: 362 SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421 Query: 431 FKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRN 472 A N + + G+A+E+AL +E +C +V K R Sbjct: 422 DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRK 481 Query: 473 PKVAEIPFNSTNKYQLSIHEREDSP----QSHVLVMKGAPERILDRCSTILVQGKEIPLD 528 E S ++ +S++ P Q + +KGAPE +++RCS++ V + PL Sbjct: 482 EFTLEF---SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLT 538 Query: 529 KEMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLM 586 ++ + G + R L + P K + + + T+ L FVG + Sbjct: 539 PTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETD-LTFVGCV 597 Query: 587 SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLN 646 M+DPPR V + +C AGI+V+M+TGD+ TA AI + +GI + ED+A + Sbjct: 598 GMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVAGK-- 651 Query: 647 IPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQG 706 G + D++ EQ + + T FAR P K IVE Q Sbjct: 652 --------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHKSRIVENLQSFN 695 Query: 707 AIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIF 766 I A+TGDGVND+PALKKA+IGIAMG SG+ V+K AA+M+L DDNFASIV VEEGR I+ Sbjct: 696 EITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIY 754 Query: 767 DNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAES 826 N+K+ I Y ++SN+ E+ L I +P L V +L ++L TD +PA +L + + Sbjct: 755 SNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDL 814 Query: 827 DIMKRQPRNSQTDKLVNERLI--SMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIR 884 DIM++ PR S + L++ L +A G + + +FV AE + L Sbjct: 815 DIMEKLPR-SPREALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNF 873 Query: 885 LDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQ 944 L + N L E +E R T + +V ++ + + + S+ + Sbjct: 874 LKCSED--NPLFAGIDCE-VFESRFPT-----TMALSVLVTIEMCNALNSVSENQSLLRM 925 Query: 945 -GMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRK 1003 N L+ + AL + P + + ++ PL W SL + + DE K Sbjct: 926 PPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVILLDEALK 985 Query: 1004 LILRR------YPG 1011 + R YPG Sbjct: 986 YLSRNHMHACLYPG 999 >gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo sapiens] Length = 1044 Score = 377 bits (968), Expect = e-104 Identities = 307/1034 (29%), Positives = 483/1034 (46%), Gaps = 103/1034 (9%) Query: 42 HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 101 H L ++ R + V GL+ + R GPN L W Q + Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64 Query: 102 LWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKN 161 L + A++ F+ + E E + +V+ +++ +QE + +++ K Sbjct: 65 LLLAALVSFVLAWFE---EGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121 Query: 162 MVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRIIS--SHGCKVDNSSLT 217 P+ VIR K +I A ++V GD+VEV GD+VPADLR+I S +VD S LT Sbjct: 122 YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181 Query: 218 GESEPQTRSPEFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASG 274 GES T+ E + + +N+ F TN G A G+ +ATG T +G+I + + Sbjct: 182 GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241 Query: 275 LEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IG 324 +E RTP+ +++ F + ++ + V+ +V+++ G SWL ++ + Sbjct: 242 VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301 Query: 325 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 384 + VA +PEGL A +T CL L +RMARKN +V++L +VETLG TS ICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 385 TVAHMWFDNQ-------IHE---ADTTEDQSGATFDKRSPT----WTALSRIAGLCNRAV 430 +V M+ + +HE + TT G P + L +A +C Sbjct: 362 SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421 Query: 431 FKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRN 472 A N + + G+A+E+AL +E +C +V K R Sbjct: 422 DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRK 481 Query: 473 PKVAEIPFNSTNKYQLSIHEREDSP----QSHVLVMKGAPERILDRCSTILVQGKEIPLD 528 E S ++ +S++ P Q + +KGAPE +++RCS++ V + PL Sbjct: 482 EFTLEF---SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLT 538 Query: 529 KEMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLM 586 ++ + G + R L + P K + + + T+ L FVG + Sbjct: 539 PTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETD-LTFVGCV 597 Query: 587 SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLN 646 M+DPPR V + +C AGI+V+M+TGD+ TA AI + +GI + ED+A + Sbjct: 598 GMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVAGK-- 651 Query: 647 IPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQG 706 G + D++ EQ + + T FAR P K IVE Q Sbjct: 652 --------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHKSRIVENLQSFN 695 Query: 707 AIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIF 766 I A+TGDGVND+PALKKA+IGIAMG SG+ V+K AA+M+L DDNFASIV VEEGR I+ Sbjct: 696 EITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIY 754 Query: 767 DNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAES 826 N+K+ I Y ++SN+ E+ L I +P L V +L ++L TD +PA +L + + Sbjct: 755 SNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDL 814 Query: 827 DIMKRQPRNSQTDKLVNERLI--SMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIR 884 DIM++ PR S + L++ L +A G + + +FV AE + L Sbjct: 815 DIMEKLPR-SPREALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNF 873 Query: 885 LDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQ 944 L + N L E +E R T + +V ++ + + + S+ + Sbjct: 874 LKCSED--NPLFAGIDCE-VFESRFPT-----TMALSVLVTIEMCNALNSVSENQSLLRM 925 Query: 945 -GMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRK 1003 N L+ + AL + P + + ++ PL W SL + + DE K Sbjct: 926 PPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVILLDEALK 985 Query: 1004 LILRR------YPG 1011 + R YPG Sbjct: 986 YLSRNHMHACLYPG 999 >gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo sapiens] Length = 1052 Score = 377 bits (968), Expect = e-104 Identities = 307/1034 (29%), Positives = 483/1034 (46%), Gaps = 103/1034 (9%) Query: 42 HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 101 H L ++ R + V GL+ + R GPN L W Q + Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64 Query: 102 LWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKN 161 L + A++ F+ + E E + +V+ +++ +QE + +++ K Sbjct: 65 LLLAALVSFVLAWFE---EGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121 Query: 162 MVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRIIS--SHGCKVDNSSLT 217 P+ VIR K +I A ++V GD+VEV GD+VPADLR+I S +VD S LT Sbjct: 122 YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181 Query: 218 GESEPQTRSPEFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASG 274 GES T+ E + + +N+ F TN G A G+ +ATG T +G+I + + Sbjct: 182 GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241 Query: 275 LEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IG 324 +E RTP+ +++ F + ++ + V+ +V+++ G SWL ++ + Sbjct: 242 VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301 Query: 325 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 384 + VA +PEGL A +T CL L +RMARKN +V++L +VETLG TS ICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 385 TVAHMWFDNQ-------IHE---ADTTEDQSGATFDKRSPT----WTALSRIAGLCNRAV 430 +V M+ + +HE + TT G P + L +A +C Sbjct: 362 SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421 Query: 431 FKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRN 472 A N + + G+A+E+AL +E +C +V K R Sbjct: 422 DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRK 481 Query: 473 PKVAEIPFNSTNKYQLSIHEREDSP----QSHVLVMKGAPERILDRCSTILVQGKEIPLD 528 E S ++ +S++ P Q + +KGAPE +++RCS++ V + PL Sbjct: 482 EFTLEF---SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLT 538 Query: 529 KEMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLM 586 ++ + G + R L + P K + + + T+ L FVG + Sbjct: 539 PTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETD-LTFVGCV 597 Query: 587 SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLN 646 M+DPPR V + +C AGI+V+M+TGD+ TA AI + +GI + ED+A + Sbjct: 598 GMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVAGK-- 651 Query: 647 IPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQG 706 G + D++ EQ + + T FAR P K IVE Q Sbjct: 652 --------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHKSRIVENLQSFN 695 Query: 707 AIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIF 766 I A+TGDGVND+PALKKA+IGIAMG SG+ V+K AA+M+L DDNFASIV VEEGR I+ Sbjct: 696 EITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIY 754 Query: 767 DNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAES 826 N+K+ I Y ++SN+ E+ L I +P L V +L ++L TD +PA +L + + Sbjct: 755 SNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDL 814 Query: 827 DIMKRQPRNSQTDKLVNERLI--SMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIR 884 DIM++ PR S + L++ L +A G + + +FV AE + L Sbjct: 815 DIMEKLPR-SPREALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNF 873 Query: 885 LDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQ 944 L + N L E +E R T + +V ++ + + + S+ + Sbjct: 874 LKCSED--NPLFAGIDCE-VFESRFPT-----TMALSVLVTIEMCNALNSVSENQSLLRM 925 Query: 945 -GMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRK 1003 N L+ + AL + P + + ++ PL W SL + + DE K Sbjct: 926 PPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVILLDEALK 985 Query: 1004 LILRR------YPG 1011 + R YPG Sbjct: 986 YLSRNHMHACLYPG 999 >gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo sapiens] Length = 999 Score = 377 bits (967), Expect = e-104 Identities = 304/1026 (29%), Positives = 481/1026 (46%), Gaps = 97/1026 (9%) Query: 42 HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 101 H L ++ R + V GL+ + R GPN L W Q + Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64 Query: 102 LWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKN 161 L + A++ F+ + E E + +V+ +++ +QE + +++ K Sbjct: 65 LLLAALVSFVLAWFE---EGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121 Query: 162 MVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRIIS--SHGCKVDNSSLT 217 P+ VIR K +I A ++V GD+VEV GD+VPADLR+I S +VD S LT Sbjct: 122 YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181 Query: 218 GESEPQTRSPEFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASG 274 GES T+ E + + +N+ F TN G A G+ +ATG T +G+I + + Sbjct: 182 GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241 Query: 275 LEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IG 324 +E RTP+ +++ F + ++ + V+ +V+++ G SWL ++ + Sbjct: 242 VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301 Query: 325 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 384 + VA +PEGL A +T CL L +RMARKN +V++L +VETLG TS ICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 385 TVAHMWFDNQ-------IHE---ADTTEDQSGATFDKRSPT----WTALSRIAGLCNRAV 430 +V M+ + +HE + TT G P + L +A +C Sbjct: 362 SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421 Query: 431 FKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRN 472 A N + + G+A+E+AL +E +C +V K R Sbjct: 422 DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRK 481 Query: 473 PKVAEIPFNSTNKYQLSIHEREDSP----QSHVLVMKGAPERILDRCSTILVQGKEIPLD 528 E S ++ +S++ P Q + +KGAPE +++RCS++ V + PL Sbjct: 482 EFTLEF---SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLT 538 Query: 529 KEMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLM 586 ++ + G + R L + P K + + + T+ L FVG + Sbjct: 539 PTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETD-LTFVGCV 597 Query: 587 SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLN 646 M+DPPR V + +C AGI+V+M+TGD+ TA AI + +GI + ED+A + Sbjct: 598 GMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVAGK-- 651 Query: 647 IPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQG 706 G + D++ EQ + + T FAR P K IVE Q Sbjct: 652 --------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHKSRIVENLQSFN 695 Query: 707 AIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIF 766 I A+TGDGVND+PALKKA+IGIAMG SG+ V+K AA+M+L DDNFASIV VEEGR I+ Sbjct: 696 EITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIY 754 Query: 767 DNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAES 826 N+K+ I Y ++SN+ E+ L I +P L V +L ++L TD +PA +L + + Sbjct: 755 SNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDL 814 Query: 827 DIMKRQPRNSQTDKLVNERLI--SMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIR 884 DIM++ PR S + L++ L +A G + + +FV AE + L Sbjct: 815 DIMEKLPR-SPREALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNF 873 Query: 885 LDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQ 944 L + N L E +E R T + +V ++ + + + S+ + Sbjct: 874 LKCSED--NPLFAGIDCE-VFESRFPT-----TMALSVLVTIEMCNALNSVSENQSLLRM 925 Query: 945 -GMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRK 1003 N L+ + AL + P + + ++ PL W SL + + DE K Sbjct: 926 PPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVILLDEALK 985 Query: 1004 LILRRY 1009 + R + Sbjct: 986 YLSRNH 991 >gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo sapiens] Length = 998 Score = 377 bits (967), Expect = e-104 Identities = 304/1026 (29%), Positives = 481/1026 (46%), Gaps = 97/1026 (9%) Query: 42 HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 101 H L ++ R + V GL+ + R GPN L W Q + Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64 Query: 102 LWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKN 161 L + A++ F+ + E E + +V+ +++ +QE + +++ K Sbjct: 65 LLLAALVSFVLAWFE---EGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121 Query: 162 MVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRIIS--SHGCKVDNSSLT 217 P+ VIR K +I A ++V GD+VEV GD+VPADLR+I S +VD S LT Sbjct: 122 YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181 Query: 218 GESEPQTRSPEFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASG 274 GES T+ E + + +N+ F TN G A G+ +ATG T +G+I + + Sbjct: 182 GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241 Query: 275 LEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IG 324 +E RTP+ +++ F + ++ + V+ +V+++ G SWL ++ + Sbjct: 242 VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301 Query: 325 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 384 + VA +PEGL A +T CL L +RMARKN +V++L +VETLG TS ICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 385 TVAHMWFDNQ-------IHE---ADTTEDQSGATFDKRSPT----WTALSRIAGLCNRAV 430 +V M+ + +HE + TT G P + L +A +C Sbjct: 362 SVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCN 421 Query: 431 FKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRN 472 A N + + G+A+E+AL +E +C +V K R Sbjct: 422 DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRK 481 Query: 473 PKVAEIPFNSTNKYQLSIHEREDSP----QSHVLVMKGAPERILDRCSTILVQGKEIPLD 528 E S ++ +S++ P Q + +KGAPE +++RCS++ V + PL Sbjct: 482 EFTLEF---SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLT 538 Query: 529 KEMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLM 586 ++ + G + R L + P K + + + T+ L FVG + Sbjct: 539 PTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETD-LTFVGCV 597 Query: 587 SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLN 646 M+DPPR V + +C AGI+V+M+TGD+ TA AI + +GI + ED+A + Sbjct: 598 GMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TEDVAGK-- 651 Query: 647 IPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQG 706 G + D++ EQ + + T FAR P K IVE Q Sbjct: 652 --------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHKSRIVENLQSFN 695 Query: 707 AIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIF 766 I A+TGDGVND+PALKKA+IGIAMG SG+ V+K AA+M+L DDNFASIV VEEGR I+ Sbjct: 696 EITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIY 754 Query: 767 DNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAES 826 N+K+ I Y ++SN+ E+ L I +P L V +L ++L TD +PA +L + + Sbjct: 755 SNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDL 814 Query: 827 DIMKRQPRNSQTDKLVNERLI--SMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIR 884 DIM++ PR S + L++ L +A G + + +FV AE + L Sbjct: 815 DIMEKLPR-SPREALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNF 873 Query: 885 LDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQ 944 L + N L E +E R T + +V ++ + + + S+ + Sbjct: 874 LKCSED--NPLFAGIDCE-VFESRFPT-----TMALSVLVTIEMCNALNSVSENQSLLRM 925 Query: 945 -GMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRK 1003 N L+ + AL + P + + ++ PL W SL + + DE K Sbjct: 926 PPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVILLDEALK 985 Query: 1004 LILRRY 1009 + R + Sbjct: 986 YLSRNH 991 >gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sapiens] Length = 939 Score = 375 bits (964), Expect = e-104 Identities = 266/847 (31%), Positives = 426/847 (50%), Gaps = 81/847 (9%) Query: 43 KLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILL 102 +L + E+ Q DL GL A G N P W K+ Q +LL Sbjct: 28 ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87 Query: 103 WIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNM 162 A++ L + A+ + +A +++VT F QE +S K ++ + Sbjct: 88 LASAVISVLMHQFDDAVS-----------ITVAILIVVTVAF--VQEYRSEKSLEELSKL 134 Query: 163 VPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEP 222 VP + +REG+ A ++V GD V + GDRVPADLR+ + +D SSLTGE+ P Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194 Query: 223 QTR----SPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVG 278 ++ P T+ + NI F T G A+G+VI TG+ + G + + E Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254 Query: 279 RTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATV 338 +TP+ ++ + ++ + + ++ +LG LE + + VA +PEGL V Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314 Query: 339 TVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEA 398 TV L L RM +K +VK L VETLG + ICSDKTGTLT+N MTV H++ + +H Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374 Query: 399 DTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQE----NISVSKRDTA-GDASESA 453 T G +++ + G N AV + + N +V + +T G +E A Sbjct: 375 VT-----GVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGA 429 Query: 454 LLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQL--SIHE-REDSPQSHVLVMKGAPER 510 L+ + + G +D K AE PF+S K+ +H ++D P+ + MKGA E+ Sbjct: 430 LI-ALAMKMGLDGLQQDYIRK-AEYPFSSEQKWMAVKCVHRTQQDRPE--ICFMKGAYEQ 485 Query: 511 ILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDT 570 ++ C+T +G+ + L ++ +D +Q +G G RVL L SG Sbjct: 486 VIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLA-----LASGP--------- 531 Query: 571 DELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGI 630 EL +L F+GL+ +IDPPR V +AV ++G+ + M+TGD TA AIA +G+ Sbjct: 532 -ELG----QLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL 586 Query: 631 ISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFART 690 S+ +++V G ++ M +QL +I+ VF R Sbjct: 587 YSKTSQSVS------------------------GEEIDAMDVQQLSQIVPKVA--VFYRA 620 Query: 691 SPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDD 750 SP+ K+ I++ Q+ G++VA+TGDGVND+ ALK ADIG+AMG +G+DV K+AADMIL+DD Sbjct: 621 SPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDD 680 Query: 751 NFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLG 810 +F +I++ +EEG+ I++N+K + + L+++I +T L + N P PL + IL I++ Sbjct: 681 DFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINII 740 Query: 811 TDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVIL 870 D PA SL E + D++++ PRN + L ++ + I I G F ++ L Sbjct: 741 MDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGTLFVFWREL 798 Query: 871 AENGFLP 877 +N P Sbjct: 799 RDNVITP 805 >gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sapiens] Length = 949 Score = 375 bits (964), Expect = e-104 Identities = 266/847 (31%), Positives = 426/847 (50%), Gaps = 81/847 (9%) Query: 43 KLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILL 102 +L + E+ Q DL GL A G N P W K+ Q +LL Sbjct: 28 ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87 Query: 103 WIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNM 162 A++ L + A+ + +A +++VT F QE +S K ++ + Sbjct: 88 LASAVISVLMHQFDDAVS-----------ITVAILIVVTVAF--VQEYRSEKSLEELSKL 134 Query: 163 VPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEP 222 VP + +REG+ A ++V GD V + GDRVPADLR+ + +D SSLTGE+ P Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194 Query: 223 QTR----SPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVG 278 ++ P T+ + NI F T G A+G+VI TG+ + G + + E Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254 Query: 279 RTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATV 338 +TP+ ++ + ++ + + ++ +LG LE + + VA +PEGL V Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314 Query: 339 TVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEA 398 TV L L RM +K +VK L VETLG + ICSDKTGTLT+N MTV H++ + +H Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374 Query: 399 DTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQE----NISVSKRDTA-GDASESA 453 T G +++ + G N AV + + N +V + +T G +E A Sbjct: 375 VT-----GVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGA 429 Query: 454 LLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQL--SIHE-REDSPQSHVLVMKGAPER 510 L+ + + G +D K AE PF+S K+ +H ++D P+ + MKGA E+ Sbjct: 430 LI-ALAMKMGLDGLQQDYIRK-AEYPFSSEQKWMAVKCVHRTQQDRPE--ICFMKGAYEQ 485 Query: 511 ILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDT 570 ++ C+T +G+ + L ++ +D +Q +G G RVL L SG Sbjct: 486 VIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLA-----LASGP--------- 531 Query: 571 DELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGI 630 EL +L F+GL+ +IDPPR V +AV ++G+ + M+TGD TA AIA +G+ Sbjct: 532 -ELG----QLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL 586 Query: 631 ISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFART 690 S+ +++V G ++ M +QL +I+ VF R Sbjct: 587 YSKTSQSVS------------------------GEEIDAMDVQQLSQIVPKVA--VFYRA 620 Query: 691 SPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDD 750 SP+ K+ I++ Q+ G++VA+TGDGVND+ ALK ADIG+AMG +G+DV K+AADMIL+DD Sbjct: 621 SPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDD 680 Query: 751 NFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLG 810 +F +I++ +EEG+ I++N+K + + L+++I +T L + N P PL + IL I++ Sbjct: 681 DFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINII 740 Query: 811 TDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVIL 870 D PA SL E + D++++ PRN + L ++ + I I G F ++ L Sbjct: 741 MDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGTLFVFWREL 798 Query: 871 AENGFLP 877 +N P Sbjct: 799 RDNVITP 805 >gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sapiens] Length = 888 Score = 375 bits (964), Expect = e-104 Identities = 266/847 (31%), Positives = 426/847 (50%), Gaps = 81/847 (9%) Query: 43 KLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILL 102 +L + E+ Q DL GL A G N P W K+ Q +LL Sbjct: 28 ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87 Query: 103 WIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNM 162 A++ L + A+ + +A +++VT F QE +S K ++ + Sbjct: 88 LASAVISVLMHQFDDAVS-----------ITVAILIVVTVAF--VQEYRSEKSLEELSKL 134 Query: 163 VPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEP 222 VP + +REG+ A ++V GD V + GDRVPADLR+ + +D SSLTGE+ P Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194 Query: 223 QTR----SPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVG 278 ++ P T+ + NI F T G A+G+VI TG+ + G + + E Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254 Query: 279 RTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATV 338 +TP+ ++ + ++ + + ++ +LG LE + + VA +PEGL V Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314 Query: 339 TVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEA 398 TV L L RM +K +VK L VETLG + ICSDKTGTLT+N MTV H++ + +H Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374 Query: 399 DTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQE----NISVSKRDTA-GDASESA 453 T G +++ + G N AV + + N +V + +T G +E A Sbjct: 375 VT-----GVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGA 429 Query: 454 LLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQL--SIHE-REDSPQSHVLVMKGAPER 510 L+ + + G +D K AE PF+S K+ +H ++D P+ + MKGA E+ Sbjct: 430 LI-ALAMKMGLDGLQQDYIRK-AEYPFSSEQKWMAVKCVHRTQQDRPE--ICFMKGAYEQ 485 Query: 511 ILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDT 570 ++ C+T +G+ + L ++ +D +Q +G G RVL L SG Sbjct: 486 VIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLA-----LASGP--------- 531 Query: 571 DELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGI 630 EL +L F+GL+ +IDPPR V +AV ++G+ + M+TGD TA AIA +G+ Sbjct: 532 -ELG----QLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL 586 Query: 631 ISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFART 690 S+ +++V G ++ M +QL +I+ VF R Sbjct: 587 YSKTSQSVS------------------------GEEIDAMDVQQLSQIVPKVA--VFYRA 620 Query: 691 SPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDD 750 SP+ K+ I++ Q+ G++VA+TGDGVND+ ALK ADIG+AMG +G+DV K+AADMIL+DD Sbjct: 621 SPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDD 680 Query: 751 NFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLG 810 +F +I++ +EEG+ I++N+K + + L+++I +T L + N P PL + IL I++ Sbjct: 681 DFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINII 740 Query: 811 TDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVIL 870 D PA SL E + D++++ PRN + L ++ + I I G F ++ L Sbjct: 741 MDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGTLFVFWREL 798 Query: 871 AENGFLP 877 +N P Sbjct: 799 RDNVITP 805 >gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sapiens] Length = 919 Score = 375 bits (964), Expect = e-104 Identities = 266/847 (31%), Positives = 426/847 (50%), Gaps = 81/847 (9%) Query: 43 KLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILL 102 +L + E+ Q DL GL A G N P W K+ Q +LL Sbjct: 28 ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87 Query: 103 WIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNM 162 A++ L + A+ + +A +++VT F QE +S K ++ + Sbjct: 88 LASAVISVLMHQFDDAVS-----------ITVAILIVVTVAF--VQEYRSEKSLEELSKL 134 Query: 163 VPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEP 222 VP + +REG+ A ++V GD V + GDRVPADLR+ + +D SSLTGE+ P Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194 Query: 223 QTR----SPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVG 278 ++ P T+ + NI F T G A+G+VI TG+ + G + + E Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254 Query: 279 RTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATV 338 +TP+ ++ + ++ + + ++ +LG LE + + VA +PEGL V Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314 Query: 339 TVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEA 398 TV L L RM +K +VK L VETLG + ICSDKTGTLT+N MTV H++ + +H Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374 Query: 399 DTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQE----NISVSKRDTA-GDASESA 453 T G +++ + G N AV + + N +V + +T G +E A Sbjct: 375 VT-----GVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGA 429 Query: 454 LLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQL--SIHE-REDSPQSHVLVMKGAPER 510 L+ + + G +D K AE PF+S K+ +H ++D P+ + MKGA E+ Sbjct: 430 LI-ALAMKMGLDGLQQDYIRK-AEYPFSSEQKWMAVKCVHRTQQDRPE--ICFMKGAYEQ 485 Query: 511 ILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDT 570 ++ C+T +G+ + L ++ +D +Q +G G RVL L SG Sbjct: 486 VIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLA-----LASGP--------- 531 Query: 571 DELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGI 630 EL +L F+GL+ +IDPPR V +AV ++G+ + M+TGD TA AIA +G+ Sbjct: 532 -ELG----QLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL 586 Query: 631 ISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFART 690 S+ +++V G ++ M +QL +I+ VF R Sbjct: 587 YSKTSQSVS------------------------GEEIDAMDVQQLSQIVPKVA--VFYRA 620 Query: 691 SPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDD 750 SP+ K+ I++ Q+ G++VA+TGDGVND+ ALK ADIG+AMG +G+DV K+AADMIL+DD Sbjct: 621 SPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDD 680 Query: 751 NFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLG 810 +F +I++ +EEG+ I++N+K + + L+++I +T L + N P PL + IL I++ Sbjct: 681 DFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINII 740 Query: 811 TDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVIL 870 D PA SL E + D++++ PRN + L ++ + I I G F ++ L Sbjct: 741 MDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGTLFVFWREL 798 Query: 871 AENGFLP 877 +N P Sbjct: 799 RDNVITP 805 >gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo sapiens] Length = 997 Score = 370 bits (950), Expect = e-102 Identities = 299/1032 (28%), Positives = 494/1032 (47%), Gaps = 110/1032 (10%) Query: 42 HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSI- 100 H +++E+ + V+ S GL+ ++ + + R G N L P ++ + F + Sbjct: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63 Query: 101 LLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFK 160 +L + A + F+ + E E + V+ +++ +QE + +++ K Sbjct: 64 ILLLAACISFVLAWFE---EGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 Query: 161 NMVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRI--ISSHGCKVDNSSL 216 P+ V R+ K +I A+++V GD+VE+ GD+VPAD+R+ I S +VD S L Sbjct: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 Query: 217 TGESEPQTRSPEFTHENPL--------ETRNICFFSTNCVEGTARGIVIATGDRTVMGRI 268 TGES + H +P+ + +N+ F TN G A G+V+ATG T +G+I Sbjct: 181 TGESVSVIK-----HTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKI 235 Query: 269 ATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL 322 E RTP+ +++ F + ++ V + ++ +++++ + G SW+ I+ Sbjct: 236 RDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYY 295 Query: 323 ----IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 378 + + VA +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGT Sbjct: 296 FKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGT 355 Query: 379 LTQNRMTVAHMWFDNQIHEADTTEDQ----SGATF---------DK--RSPTWTALSRIA 423 LT N+M+V M+ +++ E DT +G+T+ DK + L +A Sbjct: 356 LTTNQMSVCRMFILDRV-EGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELA 414 Query: 424 GLCNRAVFKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSV 465 +C A N + + G+A+E+AL +E +C SV Sbjct: 415 TICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSV 474 Query: 466 RKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQS---HVLVMKGAPERILDRCSTILVQG 522 K + E S ++ +S++ + P + +KGAPE ++DRC+ I V Sbjct: 475 IKQLMKKEFTLEF---SRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGS 531 Query: 523 KEIPLDKEMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKL 580 ++P+ ++ + E G + R L + P + + + + + T L Sbjct: 532 TKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETN-L 590 Query: 581 CFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVED 640 FVG + M+DPPR V +V CR AGI+VIM+TGD+ TA AI + +GI + + Sbjct: 591 TFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSK 650 Query: 641 IAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVE 700 A ++NP S Q D L FAR P K IVE Sbjct: 651 --AFTGREFDELNP-----------------SAQRDACLNARC---FARVEPSHKSKIVE 688 Query: 701 GCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVE 760 Q I A+TGDGVND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV VE Sbjct: 689 FLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVE 747 Query: 761 EGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLA 820 EGR I++N+K+ I Y ++SN+ E+ L P L V +L ++L TD +PA +L Sbjct: 748 EGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALG 807 Query: 821 YEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMI--QALGGFFTYFVILAENGFLPS 878 + + DIM + PRN + + L++ L Y IG A G ++ I A+ G Sbjct: 808 FNPPDLDIMNKPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGG---P 862 Query: 879 RLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRR 938 R+ +L + D D G + + T + +V ++ + + + Sbjct: 863 RVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYP----MTMALSVLVTIEMCNALNSLSEN 918 Query: 939 NSVFQQ-GMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFI 997 S+ + +N L+ + +L + Y + + ++ PL VT W SL + + Sbjct: 919 QSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVIL 978 Query: 998 YDEVRKLILRRY 1009 DE K + R Y Sbjct: 979 MDETLKFVARNY 990 >gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [Homo sapiens] Length = 1042 Score = 370 bits (950), Expect = e-102 Identities = 299/1032 (28%), Positives = 494/1032 (47%), Gaps = 110/1032 (10%) Query: 42 HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSI- 100 H +++E+ + V+ S GL+ ++ + + R G N L P ++ + F + Sbjct: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63 Query: 101 LLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFK 160 +L + A + F+ + E E + V+ +++ +QE + +++ K Sbjct: 64 ILLLAACISFVLAWFE---EGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 Query: 161 NMVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRI--ISSHGCKVDNSSL 216 P+ V R+ K +I A+++V GD+VE+ GD+VPAD+R+ I S +VD S L Sbjct: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 Query: 217 TGESEPQTRSPEFTHENPL--------ETRNICFFSTNCVEGTARGIVIATGDRTVMGRI 268 TGES + H +P+ + +N+ F TN G A G+V+ATG T +G+I Sbjct: 181 TGESVSVIK-----HTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKI 235 Query: 269 ATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL 322 E RTP+ +++ F + ++ V + ++ +++++ + G SW+ I+ Sbjct: 236 RDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYY 295 Query: 323 ----IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 378 + + VA +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGT Sbjct: 296 FKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGT 355 Query: 379 LTQNRMTVAHMWFDNQIHEADTTEDQ----SGATF---------DK--RSPTWTALSRIA 423 LT N+M+V M+ +++ E DT +G+T+ DK + L +A Sbjct: 356 LTTNQMSVCRMFILDRV-EGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELA 414 Query: 424 GLCNRAVFKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSV 465 +C A N + + G+A+E+AL +E +C SV Sbjct: 415 TICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSV 474 Query: 466 RKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQS---HVLVMKGAPERILDRCSTILVQG 522 K + E S ++ +S++ + P + +KGAPE ++DRC+ I V Sbjct: 475 IKQLMKKEFTLEF---SRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGS 531 Query: 523 KEIPLDKEMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKL 580 ++P+ ++ + E G + R L + P + + + + + T L Sbjct: 532 TKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETN-L 590 Query: 581 CFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVED 640 FVG + M+DPPR V +V CR AGI+VIM+TGD+ TA AI + +GI + + Sbjct: 591 TFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSK 650 Query: 641 IAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVE 700 A ++NP S Q D L FAR P K IVE Sbjct: 651 --AFTGREFDELNP-----------------SAQRDACLNARC---FARVEPSHKSKIVE 688 Query: 701 GCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVE 760 Q I A+TGDGVND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV VE Sbjct: 689 FLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVE 747 Query: 761 EGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLA 820 EGR I++N+K+ I Y ++SN+ E+ L P L V +L ++L TD +PA +L Sbjct: 748 EGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALG 807 Query: 821 YEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMI--QALGGFFTYFVILAENGFLPS 878 + + DIM + PRN + + L++ L Y IG A G ++ I A+ G Sbjct: 808 FNPPDLDIMNKPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGG---P 862 Query: 879 RLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRR 938 R+ +L + D D G + + T + +V ++ + + + Sbjct: 863 RVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYP----MTMALSVLVTIEMCNALNSLSEN 918 Query: 939 NSVFQQ-GMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFI 997 S+ + +N L+ + +L + Y + + ++ PL VT W SL + + Sbjct: 919 QSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVIL 978 Query: 998 YDEVRKLILRRY 1009 DE K + R Y Sbjct: 979 MDETLKFVARNY 990 >gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo sapiens] Length = 946 Score = 361 bits (926), Expect = 2e-99 Identities = 274/869 (31%), Positives = 415/869 (47%), Gaps = 104/869 (11%) Query: 4 GAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDH---KLSLDELGRKYQVDLSKG 60 G GR+Y E ++ + K +++ KK A+ K ++L R + VDL G Sbjct: 17 GGGRQYQALEKDEEEALIDEQSELKAIEKEKKVTALPPKEACKCQKEDLARAFCVDLHTG 76 Query: 61 LTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAME 120 L+ G N + P W K+ Q +LL A++ L + A Sbjct: 77 LSEFSVTQRRLAHGWNEFVADNSEPVWKKYLDQFKNPLILLLLGSALVSVLTKEYEDA-- 134 Query: 121 DEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINA 180 V +A V+V ++ QE +S K ++ MVP + +REG+ + A Sbjct: 135 -----------VSIATAVLVVVTVAFIQEYRSEKSLEELTKMVPPECNCLREGKLQHLLA 183 Query: 181 EEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEP--QTRSPEFTHENPLETR 238 E+V GD+V + GDR+PAD+R+ VD SS TGE+EP +T SP + Sbjct: 184 RELVPGDVVSLSIGDRIPADIRLTEVTDLLVDESSFTGEAEPCSKTDSPLTGGGDLTTLS 243 Query: 239 NICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAV 298 NI F T G +G+VI TG+ + G + + E +TP+ ++ + +T + Sbjct: 244 NIVFMGTLVQYGRGQGVVIGTGESSQFGEVFKMMQAEETPKTPLQKSMDRLGKQLT---L 300 Query: 299 FLGVSFFVLSLILGYSWLEAV----IFLIGI--IVANVPEGLLATVTVCLTLTAKRMARK 352 F SF ++ LI+ W + +F IG+ VA +PEGL V V L L RMA+K Sbjct: 301 F---SFGIIGLIMLIGWSQGKQLLSMFTIGVSLAVAAIPEGLPIVVMVTLVLGVLRMAKK 357 Query: 353 NCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKR 412 +VK L VETLG S +CSDKTGTLT N MTV + + + + SG +D + Sbjct: 358 RVIVKKLPIVETLGCCSVLCSDKTGTLTANEMTVTQLVTSDGLRA-----EVSGVGYDGQ 412 Query: 413 S-----PTWTALSRIAGLCNRAVFKAG--QENISVSKRDTAGDASESALLK-CIELSCGS 464 P+ + + + + +AG N + K G +E AL+ +++ Sbjct: 413 GTVCLLPSKEVIKEFSNVSVGKLVEAGCVANNAVIRKNAVMGQPTEGALMALAMKMDLSD 472 Query: 465 VRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKE 524 ++ R EIPF+S K+ + Q + MKGA E ++ C+ G Sbjct: 473 IKNSYIRKK---EIPFSSEQKWMAVKCSLKTEDQEDIYFMKGALEEVIRYCTMYNNGGIP 529 Query: 525 IPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVG 584 +PL + + +G LG RVL L SG EL +L F+G Sbjct: 530 LPLTPQQRSFCLQEEKRMGSLGLRVLA-----LASGP----------ELG----RLTFLG 570 Query: 585 LMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAAR 644 L+ +IDPPR V +AV +G+ V M+TGD TA AI + +G+ + Sbjct: 571 LVGIIDPPRVGVKEAVQVLSESGVSVKMITGDALETALAIGRNIGLCN------------ 618 Query: 645 LNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTE------IVFARTSPQQKLII 698 L+ M+ E++D + K VF RTSP+ KL I Sbjct: 619 --------------------GKLQAMSGEEVDSVEKGELADRVGKVSVFFRTSPKHKLKI 658 Query: 699 VEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTG 758 ++ Q GAIVA+TGDGVND+ ALK ADIGIAMG +G+DVSK+AA+MIL+DD+F++I+ Sbjct: 659 IKALQESGAIVAMTGDGVNDAVALKSADIGIAMGQTGTDVSKEAANMILVDDDFSAIMNA 718 Query: 759 VEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAIS 818 VEEG+ IF N+K + + L+++I ++ L + N+P PL + IL I++ D PA S Sbjct: 719 VEEGKGIFYNIKNFVRFQLSTSISALSLITLSTVFNLPSPLNAMQILWINIIMDGPPAQS 778 Query: 819 LAYEAAESDIMKRQPRNSQTDKLVNERLI 847 L E + D RQP S D +++ LI Sbjct: 779 LGVEPVDKDAF-RQPPRSVRDTILSRALI 806 >gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [Homo sapiens] Length = 994 Score = 360 bits (925), Expect = 3e-99 Identities = 300/1039 (28%), Positives = 474/1039 (45%), Gaps = 117/1039 (11%) Query: 42 HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 101 H + +E + V + GLT + + L + G N L W Q + Sbjct: 5 HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 64 Query: 102 LWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKN 161 L + A + F+ + E E + V+ ++I +QE + +++ K Sbjct: 65 LLLAACISFVLAWFE---EGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKE 121 Query: 162 MVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRI--ISSHGCKVDNSSLT 217 P+ V R K +I A ++V GD+VEV GD+VPAD+RI I S +VD S LT Sbjct: 122 YEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILT 181 Query: 218 GESEPQTRSPEFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASG 274 GES + E + + +N+ F TN G A GIV TG T +G+I + Sbjct: 182 GESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAA 241 Query: 275 LEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IG 324 E +TP+ +++ F + ++ V + V+ +++++ + G SW I+ + Sbjct: 242 TEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVA 301 Query: 325 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 384 + VA +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 385 TVAHMWFD----------NQIHEADTTEDQSGATFDKRSPT----WTALSRIAGLCNRAV 430 +V M+ N+ +T G P + L +A +C Sbjct: 362 SVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCN 421 Query: 431 FKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRN 472 + N + + G+A+E+AL +E +C SV +R Sbjct: 422 DSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSV--IRQLM 479 Query: 473 PKVAEIPFNSTNKYQLSIHEREDSPQSHV---LVMKGAPERILDRCSTILVQGKEIPLDK 529 K + F+ K S ++ V + +KGAPE ++DRC+ + V +PL Sbjct: 480 KKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTG 539 Query: 530 EMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMS 587 +++ E G + R L + P + L + T+ L FVG++ Sbjct: 540 PVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETD-LTFVGVVG 598 Query: 588 MIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNI 647 M+DPPR V ++ CR AGI+VIM+TGD+ TA AI + +GI E NE V D A Sbjct: 599 MLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGE-NEEVADRAYT--- 654 Query: 648 PMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGA 707 G + D+ + E + FAR P K IVE Q Sbjct: 655 ----------------GREFDDLPLAEQREACRR--ACCFARVEPSHKSKIVEYLQSYDE 696 Query: 708 IVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFD 767 I A+TGDGVND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV VEEGR I++ Sbjct: 697 ITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYN 755 Query: 768 NLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESD 827 N+K+ I Y ++SN+ E+ L +P L V +L ++L TD +PA +L + + D Sbjct: 756 NMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLD 815 Query: 828 IMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDW 887 IM R PR+ + E LIS G + FF Y I G++ + +G W Sbjct: 816 IMDRPPRSPK------EPLIS------GWL-----FFRYMAI---GGYVGAATVGAAAWW 855 Query: 888 -----DDRTMNDLEDSYGQEWTYEQRKVVEFTCH--------TAFFASIVVVQWADLIIC 934 D +N + ++ + T + C T + +V ++ + + Sbjct: 856 FLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMCNALNS 915 Query: 935 KTRRNSVFQQGMKNKILIFG-LLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSL 993 + S+ + I + G + +L + Y + + ++ L +T W SL Sbjct: 916 LSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMVLKISL 975 Query: 994 LIFIYDEVRKLILRRYPGG 1012 + DE+ K + R Y G Sbjct: 976 PVIGLDEILKFVARNYLEG 994 >gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [Homo sapiens] Length = 1001 Score = 360 bits (924), Expect = 4e-99 Identities = 299/1036 (28%), Positives = 473/1036 (45%), Gaps = 117/1036 (11%) Query: 42 HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 101 H + +E + V + GLT + + L + G N L W Q + Sbjct: 5 HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 64 Query: 102 LWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKN 161 L + A + F+ + E E + V+ ++I +QE + +++ K Sbjct: 65 LLLAACISFVLAWFE---EGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKE 121 Query: 162 MVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRI--ISSHGCKVDNSSLT 217 P+ V R K +I A ++V GD+VEV GD+VPAD+RI I S +VD S LT Sbjct: 122 YEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILT 181 Query: 218 GESEPQTRSPEFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASG 274 GES + E + + +N+ F TN G A GIV TG T +G+I + Sbjct: 182 GESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAA 241 Query: 275 LEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IG 324 E +TP+ +++ F + ++ V + V+ +++++ + G SW I+ + Sbjct: 242 TEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVA 301 Query: 325 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 384 + VA +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 385 TVAHMWFD----------NQIHEADTTEDQSGATFDKRSPT----WTALSRIAGLCNRAV 430 +V M+ N+ +T G P + L +A +C Sbjct: 362 SVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCN 421 Query: 431 FKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRN 472 + N + + G+A+E+AL +E +C SV +R Sbjct: 422 DSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSV--IRQLM 479 Query: 473 PKVAEIPFNSTNKYQLSIHEREDSPQSHV---LVMKGAPERILDRCSTILVQGKEIPLDK 529 K + F+ K S ++ V + +KGAPE ++DRC+ + V +PL Sbjct: 480 KKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTG 539 Query: 530 EMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMS 587 +++ E G + R L + P + L + T+ L FVG++ Sbjct: 540 PVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETD-LTFVGVVG 598 Query: 588 MIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNI 647 M+DPPR V ++ CR AGI+VIM+TGD+ TA AI + +GI E NE V D A Sbjct: 599 MLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGE-NEEVADRAYT--- 654 Query: 648 PMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGA 707 G + D+ + E + FAR P K IVE Q Sbjct: 655 ----------------GREFDDLPLAEQREACRR--ACCFARVEPSHKSKIVEYLQSYDE 696 Query: 708 IVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFD 767 I A+TGDGVND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV VEEGR I++ Sbjct: 697 ITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYN 755 Query: 768 NLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESD 827 N+K+ I Y ++SN+ E+ L +P L V +L ++L TD +PA +L + + D Sbjct: 756 NMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLD 815 Query: 828 IMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDW 887 IM R PR+ + E LIS G + FF Y I G++ + +G W Sbjct: 816 IMDRPPRSPK------EPLIS------GWL-----FFRYMAI---GGYVGAATVGAAAWW 855 Query: 888 -----DDRTMNDLEDSYGQEWTYEQRKVVEFTCH--------TAFFASIVVVQWADLIIC 934 D +N + ++ + T + C T + +V ++ + + Sbjct: 856 FLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMCNALNS 915 Query: 935 KTRRNSVFQQGMKNKILIFG-LLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSL 993 + S+ + I + G + +L + Y + + ++ L +T W SL Sbjct: 916 LSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMVLKISL 975 Query: 994 LIFIYDEVRKLILRRY 1009 + DE+ K + R Y Sbjct: 976 PVIGLDEILKFVARNY 991 >gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 [Homo sapiens] Length = 1015 Score = 341 bits (874), Expect = 2e-93 Identities = 284/1022 (27%), Positives = 479/1022 (46%), Gaps = 117/1022 (11%) Query: 42 HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSI- 100 H +++E+ + V+ S GL+ ++ + + R G N L P ++ + F + Sbjct: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63 Query: 101 LLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFK 160 +L + A + F+ + E E + V+ +++ +QE + +++ K Sbjct: 64 ILLLAACISFVLAWFE---EGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 Query: 161 NMVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTG 218 P+ V R+ K +I A+++V GD+VE+ G ++ S+ Sbjct: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAG------------------ESVSVIK 162 Query: 219 ESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVG 278 ++P P ++ + +N+ F TN G A G+V+ATG T +G+I E Sbjct: 163 HTDP-VPDPRAVNQ---DKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQE 218 Query: 279 RTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IGIIVA 328 RTP+ +++ F + ++ V + ++ +++++ + G SW+ I+ + + VA Sbjct: 219 RTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVA 278 Query: 329 NVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAH 388 +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M+V Sbjct: 279 AIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCR 338 Query: 389 MWFDNQIHEADTTEDQ----SGATF---------DK--RSPTWTALSRIAGLCNRAVFKA 433 M+ +++ E DT +G+T+ DK + L +A +C A Sbjct: 339 MFILDRV-EGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSA 397 Query: 434 GQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRNPKV 475 N + + G+A+E+AL +E +C SV K + Sbjct: 398 LDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFT 457 Query: 476 AEIPFNSTNKYQLSIHEREDSPQS---HVLVMKGAPERILDRCSTILVQGKEIPLDKEMQ 532 E S ++ +S++ + P + +KGAPE ++DRC+ I V ++P+ ++ Sbjct: 458 LEF---SRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVK 514 Query: 533 DAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMID 590 + E G + R L + P + + + + + T L FVG + M+D Sbjct: 515 QKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETN-LTFVGCVGMLD 573 Query: 591 PPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMS 650 PPR V +V CR AGI+VIM+TGD+ TA AI + +GI + + A Sbjct: 574 PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSK--AFTGREFD 631 Query: 651 QVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVA 710 ++NP S Q D L FAR P K IVE Q I A Sbjct: 632 ELNP-----------------SAQRDACLNARC---FARVEPSHKSKIVEFLQSFDEITA 671 Query: 711 VTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLK 770 +TGDGVND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV VEEGR I++N+K Sbjct: 672 MTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMK 730 Query: 771 KSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMK 830 + I Y ++SN+ E+ L P L V +L ++L TD +PA +L + + DIM Sbjct: 731 QFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMN 790 Query: 831 RQPRNSQTDKLVNERLISMAYGQIGMI--QALGGFFTYFVILAENGFLPSRLLGIRLDWD 888 + PRN + + L++ L Y IG A G ++ I A+ G R+ +L Sbjct: 791 KPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGG---PRVSFYQLSHF 845 Query: 889 DRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQ-GMK 947 + D D G + + T + +V ++ + + + S+ + + Sbjct: 846 LQCKEDNPDFEGVDCAIFESPYP----MTMALSVLVTIEMCNALNSLSENQSLLRMPPWE 901 Query: 948 NKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILR 1007 N L+ + +L + Y + + ++ PL VT W SL + + DE K + R Sbjct: 902 NIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILMDETLKFVAR 961 Query: 1008 RY 1009 Y Sbjct: 962 NY 963 >gi|49249977 Na+/K+ -ATPase alpha 4 subunit isoform 2 [Homo sapiens] Length = 165 Score = 289 bits (740), Expect = 8e-78 Identities = 132/165 (80%), Positives = 150/165 (90%) Query: 856 MIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTC 915 MIQAL GFFTYFVILAENGF P LLGIRL W+D+ +NDLEDSYGQ+WTYEQRKVVEFTC Sbjct: 1 MIQALAGFFTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTC 60 Query: 916 HTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVAL 975 TAFF +IVVVQWADLII KTRRNS+FQQGM+NK+LIFG+LEET LAAFLSY PGM VAL Sbjct: 61 QTAFFVTIVVVQWADLIISKTRRNSLFQQGMRNKVLIFGILEETLLAAFLSYTPGMDVAL 120 Query: 976 RMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 1020 RMYPLK+TWW CA PYS+LIF+YDE+RKL++R++P GWVE+ETYY Sbjct: 121 RMYPLKITWWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY 165 >gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sapiens] Length = 1198 Score = 258 bits (659), Expect = 2e-68 Identities = 238/800 (29%), Positives = 376/800 (47%), Gaps = 115/800 (14%) Query: 137 VVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDR 196 VV+VT + +E + + + Q+ V+R G+ +QI E+VVGD+ +VK GD Sbjct: 164 VVLVTAFNDWSKEKQFRGLQSRIEQ--EQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDL 221 Query: 197 VPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIV 256 +PAD I + K+D SSLTGES+ +S + ++P+ T+ +EG+ R +V Sbjct: 222 LPADGLFIQGNDLKIDESSLTGESDQVRKSVD---KDPM-----LLSGTHVMEGSGRMLV 273 Query: 257 IATGDRTVMGRIATL--ASGLEVGRTP---------IAMEIEHFIQL------------- 292 A G + G I TL A G E + AME++ Sbjct: 274 TAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEMQPLKSAEGGDADDRKKASM 333 Query: 293 -----------ITGVAVFLGVSFFVLS------LILGYS----------WLEAV------ 319 +T +AV +G + V+S L+L ++ WL Sbjct: 334 HKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQ 393 Query: 320 ----IFLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICS 373 F+IG+ +V VPEGL VT+ L + K+M + N LV++L+A ET+G+ + ICS Sbjct: 394 YFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICS 453 Query: 374 DKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKA 433 DKTGTLT NRMTV + + +H + + S T T L + + K Sbjct: 454 DKTGTLTTNRMTVVQAYVGD-VHYKEIPDPSSINT-----KTMELLINAIAINSAYTTKI 507 Query: 434 GQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNP--KVAEI-PFNSTNKYQLSI 490 + G+ +E LL + +R + P K+ ++ FNS K ++ Sbjct: 508 LPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTV 567 Query: 491 HEREDSPQSHVLVMKGAPERILDRCSTILVQGKE--IPLDKEMQDAFQNAYMELGGLGER 548 + D +S + KGA E +L +C IL E + ++ + + + G R Sbjct: 568 IKLPD--ESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLR 625 Query: 549 VLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGI 608 + + PS P D D N +L + ++ + DP R VP+A+ KC+ AGI Sbjct: 626 TICVAYRDFPSSPEP-----DWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGI 680 Query: 609 KVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLK 668 V MVTGD+ TA+AIA GII G + L + + N R ++ Sbjct: 681 TVRMVTGDNINTARAIAIKCGIIHPGEDF-------LCLEGKEFNRRIR-------NEKG 726 Query: 669 DMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGC-----QRQGAIVAVTGDGVNDSPALK 723 ++ E++D+I V AR+SP K +V+G Q +VAVTGDG ND PALK Sbjct: 727 EIEQERIDKIWPKLR--VLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALK 784 Query: 724 KADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPE 783 KAD+G AMGI+G+DV+K+A+D+IL DDNF+SIV V GR ++D++ K + + LT N+ Sbjct: 785 KADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVA 844 Query: 784 ITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQP--RNSQ-TDK 840 + PL V +L ++L D +++LA E ++ R+P RN + Sbjct: 845 VIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISR 904 Query: 841 LVNERLISMAYGQIGMIQAL 860 + + ++ A Q+ +I L Sbjct: 905 TMMKNILGHAVYQLALIFTL 924 >gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sapiens] Length = 1220 Score = 232 bits (591), Expect = 2e-60 Identities = 230/802 (28%), Positives = 359/802 (44%), Gaps = 160/802 (19%) Query: 137 VVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDR 196 VV+VT + +E + + + Q+ VIR G+ +Q+ +VVGD+ +VK GD Sbjct: 167 VVLVTAFNDWSKEKQFRGLQSRIEQ--EQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDL 224 Query: 197 VPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIV 256 +PAD +I ++ K+D SSLTGES+ +S + ++P+ T+ +EG+ R +V Sbjct: 225 LPADGVLIQANDLKIDESSLTGESDHVRKSAD---KDPM-----LLSGTHVMEGSGRMVV 276 Query: 257 IATGDRTVMGRIATLA------------------SGLEVGRT-------PIAMEIEHFIQ 291 A G + G I TL +E +T +AME++ Sbjct: 277 TAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKS 336 Query: 292 L--------------------------ITGVAVFLGVSFFVLSLIL-------------- 311 +T +AV +G + V+S I Sbjct: 337 AEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFV 396 Query: 312 --GYSWLEA-----VIFLIGIIVANVPEGLLAT---VTVCLTLTAKRMARKNCLVKNL-- 359 G +WL V + + + V ++A + + +T++ +K NL Sbjct: 397 VEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVR 456 Query: 360 --EAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWT 417 +A ET+G+ + ICSDKTGTLT NRMTV + G T K P + Sbjct: 457 HLDACETMGNATAICSDKTGTLTTNRMTVVQSYL--------------GDTHYKEIPAPS 502 Query: 418 ALS-RIAGLCNRAVF--KAGQENISVSKRDTA-----GDASESALLKCIELSCGSVRKMR 469 AL+ +I L A+ A I +++ A G+ +E ALL + + R Sbjct: 503 ALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVGNKTECALLGFV------LDLKR 556 Query: 470 DRNPKVAEIP---------FNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILV 520 D P +IP FNS K ++ D L KGA E +L +C+ IL Sbjct: 557 DFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDG--GFRLFSKGASEILLKKCTNILN 614 Query: 521 QGKEI----PLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFP 576 E+ P D++ D + + G R + + +G+ P D D N Sbjct: 615 SNGELRGFRPRDRD--DMVRKIIEPMACDGLRTICIAYRDFSAGQEP-----DWDNENEV 667 Query: 577 TEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNE 636 L + ++ + DP R VP+A+ KC+ AGI V MVTGD+ TA+AIA GII G + Sbjct: 668 VGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGED 727 Query: 637 TVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKL 696 L + + N R ++ ++ E+LD++ V AR+SP K Sbjct: 728 F-------LCLEGKEFNRRIR-------NEKGEIEQERLDKVWPKLR--VLARSSPTDKH 771 Query: 697 IIVEG-----CQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDN 751 +V+G Q +VAVTGDG ND PALKKAD+G AMGI+G+DV+K+A+D+IL DDN Sbjct: 772 TLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDN 831 Query: 752 FASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGT 811 F SIV V GR ++D++ K + + LT N+ + PL V +L ++L Sbjct: 832 FTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIM 891 Query: 812 DMVPAISLAYEAAESDIMKRQP 833 D +++LA E ++ R+P Sbjct: 892 DTFASLALATEPPTESLLLRKP 913 >gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sapiens] Length = 1173 Score = 232 bits (591), Expect = 2e-60 Identities = 230/802 (28%), Positives = 359/802 (44%), Gaps = 160/802 (19%) Query: 137 VVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDR 196 VV+VT + +E + + + Q+ VIR G+ +Q+ +VVGD+ +VK GD Sbjct: 167 VVLVTAFNDWSKEKQFRGLQSRIEQ--EQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDL 224 Query: 197 VPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIV 256 +PAD +I ++ K+D SSLTGES+ +S + ++P+ T+ +EG+ R +V Sbjct: 225 LPADGVLIQANDLKIDESSLTGESDHVRKSAD---KDPM-----LLSGTHVMEGSGRMVV 276 Query: 257 IATGDRTVMGRIATLA------------------SGLEVGRT-------PIAMEIEHFIQ 291 A G + G I TL +E +T +AME++ Sbjct: 277 TAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKS 336 Query: 292 L--------------------------ITGVAVFLGVSFFVLSLIL-------------- 311 +T +AV +G + V+S I Sbjct: 337 AEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFV 396 Query: 312 --GYSWLEA-----VIFLIGIIVANVPEGLLAT---VTVCLTLTAKRMARKNCLVKNL-- 359 G +WL V + + + V ++A + + +T++ +K NL Sbjct: 397 VEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVR 456 Query: 360 --EAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWT 417 +A ET+G+ + ICSDKTGTLT NRMTV + G T K P + Sbjct: 457 HLDACETMGNATAICSDKTGTLTTNRMTVVQSYL--------------GDTHYKEIPAPS 502 Query: 418 ALS-RIAGLCNRAVF--KAGQENISVSKRDTA-----GDASESALLKCIELSCGSVRKMR 469 AL+ +I L A+ A I +++ A G+ +E ALL + + R Sbjct: 503 ALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVGNKTECALLGFV------LDLKR 556 Query: 470 DRNPKVAEIP---------FNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILV 520 D P +IP FNS K ++ D L KGA E +L +C+ IL Sbjct: 557 DFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDG--GFRLFSKGASEILLKKCTNILN 614 Query: 521 QGKEI----PLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFP 576 E+ P D++ D + + G R + + +G+ P D D N Sbjct: 615 SNGELRGFRPRDRD--DMVRKIIEPMACDGLRTICIAYRDFSAGQEP-----DWDNENEV 667 Query: 577 TEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNE 636 L + ++ + DP R VP+A+ KC+ AGI V MVTGD+ TA+AIA GII G + Sbjct: 668 VGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGED 727 Query: 637 TVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKL 696 L + + N R ++ ++ E+LD++ V AR+SP K Sbjct: 728 F-------LCLEGKEFNRRIR-------NEKGEIEQERLDKVWPKLR--VLARSSPTDKH 771 Query: 697 IIVEG-----CQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDN 751 +V+G Q +VAVTGDG ND PALKKAD+G AMGI+G+DV+K+A+D+IL DDN Sbjct: 772 TLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDN 831 Query: 752 FASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGT 811 F SIV V GR ++D++ K + + LT N+ + PL V +L ++L Sbjct: 832 FTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIM 891 Query: 812 DMVPAISLAYEAAESDIMKRQP 833 D +++LA E ++ R+P Sbjct: 892 DTFASLALATEPPTESLLLRKP 913 >gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sapiens] Length = 1176 Score = 225 bits (573), Expect = 2e-58 Identities = 183/589 (31%), Positives = 289/589 (49%), Gaps = 74/589 (12%) Query: 280 TPIAMEIEHFIQLITGVAVFLGVSFFVLSL--ILGYSWLEAV----------IFLIGI-- 325 T +A++I L++ + V + V +FV+ + WL F+IG+ Sbjct: 367 TKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTV 426 Query: 326 IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMT 385 +V VPEGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGTLT NRMT Sbjct: 427 LVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMT 486 Query: 386 VAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDT 445 V + N+ H E ++ P + G+ + + I +++ Sbjct: 487 VVQAYI-NEKHYKKVPEPEA-------IPPNILSYLVTGISVNCAYTS---KILPPEKEG 535 Query: 446 A-----GDASESALLKCIELSCGSVRKMRDRNPKVA---EIPFNSTNKYQLSIHEREDSP 497 G+ +E ALL + + +R+ P+ A FNS K ++ + D Sbjct: 536 GLPRHVGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDG- 594 Query: 498 QSHVLVMKGAPERILDRCSTILVQGKEIPL--DKEMQDAFQNAYMELGGLGERVLGFCQL 555 S+ + KGA E IL +C IL E + ++ D + + G R + Sbjct: 595 -SYRIFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFR 653 Query: 556 NLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTG 615 + P+G+ P + D N L + ++ + DP R VPDA+ KC+ AGI V MVTG Sbjct: 654 DFPAGE-PEP---EWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTG 709 Query: 616 DHPITAKAIAKGVGIISEGNETV----EDIAARLNIPMSQVNPREAKACVVHGSDLKDMT 671 D+ TA+AIA GI+ G + + +D R+ ++ ++ Sbjct: 710 DNINTARAIATKCGILHPGEDFLCLEGKDFNRRIR------------------NEKGEIE 751 Query: 672 SEQLDEILKNHTEIVFARTSPQQKLIIVEGC-------QRQGAIVAVTGDGVNDSPALKK 724 E++D+I V AR+SP K +V+G QRQ +VAVTGDG ND PALKK Sbjct: 752 QERIDKIWPKLR--VLARSSPTDKHTLVKGIIDSTVSDQRQ--VVAVTGDGTNDGPALKK 807 Query: 725 ADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEI 784 AD+G AMGI+G+DV+K+A+D+IL DDNF SIV V GR ++D++ K + + LT N+ + Sbjct: 808 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV 867 Query: 785 TPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQP 833 PL V +L ++L D + +++LA E ++ R+P Sbjct: 868 IVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKP 916 Score = 67.4 bits (163), Expect = 7e-11 Identities = 45/138 (32%), Positives = 72/138 (52%), Gaps = 10/138 (7%) Query: 134 LAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKG 193 + VV+VT + +E + + + Q+ VIR G+ +QI ++ VGD+ +VK Sbjct: 163 VVCVVLVTAFNDWSKEKQFRGLQSRIEQ--EQKFTVIRGGQVIQIPVADITVGDIAQVKY 220 Query: 194 GDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTAR 253 GD +PAD +I + K+D SSLTGES+ +S L+ + T+ +EG+ R Sbjct: 221 GDLLPADGILIQGNDLKIDESSLTGESDHVKKS--------LDKDPLLLSGTHVMEGSGR 272 Query: 254 GIVIATGDRTVMGRIATL 271 +V A G + G I TL Sbjct: 273 MVVTAVGVNSQTGIIFTL 290 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.136 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 36,670,480 Number of Sequences: 37866 Number of extensions: 1598019 Number of successful extensions: 4602 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 67 Number of HSP's successfully gapped in prelim test: 14 Number of HSP's that attempted gapping in prelim test: 4239 Number of HSP's gapped (non-prelim): 179 length of query: 1020 length of database: 18,247,518 effective HSP length: 112 effective length of query: 908 effective length of database: 14,006,526 effective search space: 12717925608 effective search space used: 12717925608 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.