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Search of human proteins with 4501987
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4501987 afamin precursor [Homo sapiens]
(599 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4501987 afamin precursor [Homo sapiens] 1238 0.0
gi|4501989 alpha-fetoprotein precursor [Homo sapiens] 480 e-135
gi|4502027 albumin preproprotein [Homo sapiens] 412 e-115
gi|32483410 vitamin D-binding protein precursor [Homo sapiens] 120 3e-27
gi|15559209 interleukin 33 [Homo sapiens] 32 1.3
gi|148664238 a disintegrin and metalloprotease domain 32 [Homo s... 32 1.7
gi|113722133 senataxin [Homo sapiens] 32 2.2
gi|62460637 importin 4 [Homo sapiens] 32 2.2
gi|41152093 zinc finger protein 644 isoform 1 [Homo sapiens] 32 2.2
gi|4826730 FK506 binding protein 12-rapamycin associated protein... 31 2.8
gi|227430327 calsequestrin 1 [Homo sapiens] 31 3.7
gi|38708169 sorting nexin 25 [Homo sapiens] 31 3.7
gi|239744397 PREDICTED: hypothetical protein LOC100130348 [Homo ... 30 6.3
gi|239787094 A20-binding inhibitor of NF-kappaB activation 2 iso... 30 8.3
gi|239787092 A20-binding inhibitor of NF-kappaB activation 2 iso... 30 8.3
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens] 30 8.3
>gi|4501987 afamin precursor [Homo sapiens]
Length = 599
Score = 1238 bits (3203), Expect = 0.0
Identities = 599/599 (100%), Positives = 599/599 (100%)
Query: 1 MKLLKLTGFIFFLFFLTESLTLPTQPRDIENFNSTQKFIEDNIEYITIIAFAQYVQEATF 60
MKLLKLTGFIFFLFFLTESLTLPTQPRDIENFNSTQKFIEDNIEYITIIAFAQYVQEATF
Sbjct: 1 MKLLKLTGFIFFLFFLTESLTLPTQPRDIENFNSTQKFIEDNIEYITIIAFAQYVQEATF 60
Query: 61 EEMEKLVKDMVEYKDRCMADKTLPECSKLPNNVLQEKICAMEGLPQKHNFSHCCSKVDAQ 120
EEMEKLVKDMVEYKDRCMADKTLPECSKLPNNVLQEKICAMEGLPQKHNFSHCCSKVDAQ
Sbjct: 61 EEMEKLVKDMVEYKDRCMADKTLPECSKLPNNVLQEKICAMEGLPQKHNFSHCCSKVDAQ 120
Query: 121 RRLCFFYNKKSDVGFLPPFPTLDPEEKCQAYESNRESLLNHFLYEVARRNPFVFAPTLLT 180
RRLCFFYNKKSDVGFLPPFPTLDPEEKCQAYESNRESLLNHFLYEVARRNPFVFAPTLLT
Sbjct: 121 RRLCFFYNKKSDVGFLPPFPTLDPEEKCQAYESNRESLLNHFLYEVARRNPFVFAPTLLT 180
Query: 181 VAVHFEEVAKSCCEEQNKVNCLQTRAIPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIYI 240
VAVHFEEVAKSCCEEQNKVNCLQTRAIPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIYI
Sbjct: 181 VAVHFEEVAKSCCEEQNKVNCLQTRAIPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIYI 240
Query: 241 AILSQKFPKIEFKELISLVEDVSSNYDGCCEGDVVQCIRDTSKVMNHICSKQDSISSKIK 300
AILSQKFPKIEFKELISLVEDVSSNYDGCCEGDVVQCIRDTSKVMNHICSKQDSISSKIK
Sbjct: 241 AILSQKFPKIEFKELISLVEDVSSNYDGCCEGDVVQCIRDTSKVMNHICSKQDSISSKIK 300
Query: 301 ECCEKKIPERGQCIINSNKDDRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSR 360
ECCEKKIPERGQCIINSNKDDRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSR
Sbjct: 301 ECCEKKIPERGQCIINSNKDDRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSR 360
Query: 361 RHPDLSIPELLRIVQIYKDLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQ 420
RHPDLSIPELLRIVQIYKDLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQ
Sbjct: 361 RHPDLSIPELLRIVQIYKDLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQ 420
Query: 421 NLGKDGLKYHYLIRLTKIAPQLSTEELVSLGEKMVTAFTTCCTLSEEFACVDNLADLVFG 480
NLGKDGLKYHYLIRLTKIAPQLSTEELVSLGEKMVTAFTTCCTLSEEFACVDNLADLVFG
Sbjct: 421 NLGKDGLKYHYLIRLTKIAPQLSTEELVSLGEKMVTAFTTCCTLSEEFACVDNLADLVFG 480
Query: 481 ELCGVNENRTINPAVDHCCKTNFAFRRPCFESLKADKTYVPPPFSQDLFTFHADMCQSQN 540
ELCGVNENRTINPAVDHCCKTNFAFRRPCFESLKADKTYVPPPFSQDLFTFHADMCQSQN
Sbjct: 481 ELCGVNENRTINPAVDHCCKTNFAFRRPCFESLKADKTYVPPPFSQDLFTFHADMCQSQN 540
Query: 541 EELQRKTDRFLVNLVKLKHELTDEELQSLFTNFANVVDKCCKAESPEVCFNEESPKIGN 599
EELQRKTDRFLVNLVKLKHELTDEELQSLFTNFANVVDKCCKAESPEVCFNEESPKIGN
Sbjct: 541 EELQRKTDRFLVNLVKLKHELTDEELQSLFTNFANVVDKCCKAESPEVCFNEESPKIGN 599
>gi|4501989 alpha-fetoprotein precursor [Homo sapiens]
Length = 609
Score = 480 bits (1236), Expect = e-135
Identities = 234/592 (39%), Positives = 361/592 (60%), Gaps = 3/592 (0%)
Query: 9 FIFFLFFLTESLTLPTQPRDIENF-NSTQKFIEDNIEYITIIAFAQYVQEATFEEMEKLV 67
F+ FL TES TL I + +S Q E ++ + I FAQ+VQEAT++E+ K+V
Sbjct: 8 FLIFLLNFTESRTLHRNEYGIASILDSYQCTAEISLADLATIFFAQFVQEATYKEVSKMV 67
Query: 68 KDMVEYKDRCMADKTLPECSKLPNNVLQEKICAMEGLPQKHNFSHCCSKVDAQRRLCFFY 127
KD + ++ D+ C + E++C + + +K+ S CCS+ + R CF
Sbjct: 68 KDALTAIEKPTGDEQSSGCLENQLPAFLEELCHEKEILEKYGHSDCCSQSEEGRHNCFLA 127
Query: 128 NKKSDVGFLPPFPTLDPEEKCQAYESNRESLLNHFLYEVARRNPFVFAPTLLTVAVHFEE 187
+KK +P F +P C+AYE +RE+ +N F+YE+ARR+PF++APT+L A +++
Sbjct: 128 HKKPTPASIPLFQVPEPVTSCEAYEEDRETFMNKFIYEIARRHPFLYAPTILLWAARYDK 187
Query: 188 VAKSCCEEQNKVNCLQTRAIPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIYIAILSQKF 247
+ SCC+ +N V C QT+A VT+ L+ S +H C + FGT+ I + LSQKF
Sbjct: 188 IIPSCCKAENAVECFQTKAATVTKELRESSLLNQHACAVMKNFGTRTFQAITVTKLSQKF 247
Query: 248 PKIEFKELISLVEDVSSNYDGCCEGDVVQCIRDTSKVMNHICSKQDSISSKIKECCEKKI 307
K+ F E+ LV DV+ ++ CC GDV+ C++D K+M++ICS+QD++S+KI ECC+
Sbjct: 248 TKVNFTEIQKLVLDVAHVHEHCCRGDVLDCLQDGEKIMSYICSQQDTLSNKITECCKLTT 307
Query: 308 PERGQCIINSNKDDRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSRRHPDLSI 367
ERGQCII++ D++P+ LS +F + Q + + F A F EYSRRHP L++
Sbjct: 308 LERGQCIIHAENDEKPEGLSPNLNRFLGDRDFNQFSSGEKNIFLASFVHEYSRRHPQLAV 367
Query: 368 PELLRIVQIYKDLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQNLGKDGL 427
+LR+ + Y++LL C TENP C E++ + ++S + ++ C FQ LG+ L
Sbjct: 368 SVILRVAKGYQELLEKCFQTENPLECQDKGEEELQKYIQESQALAKRSCGLFQKLGEYYL 427
Query: 428 KYHYLIRLTKIAPQLSTEELVSLGEKMVTAFTTCCTLSEE--FACVDNLADLVFGELCGV 485
+ +L+ TK APQL++ EL+++ KM TCC LSE+ AC + AD++ G LC
Sbjct: 428 QNAFLVAYTKKAPQLTSSELMAITRKMAATAATCCQLSEDKLLACGEGAADIIIGHLCIR 487
Query: 486 NENRTINPAVDHCCKTNFAFRRPCFESLKADKTYVPPPFSQDLFTFHADMCQSQNEELQR 545
+E +NP V CC +++A RRPCF SL D+TYVPP FS D F FH D+CQ+Q LQ
Sbjct: 488 HEMTPVNPGVGQCCTSSYANRRPCFSSLVVDETYVPPAFSDDKFIFHKDLCQAQGVALQT 547
Query: 546 KTDRFLVNLVKLKHELTDEELQSLFTNFANVVDKCCKAESPEVCFNEESPKI 597
FL+NLVK K ++T+E+L+++ +F+ +++KCC+ + EVCF EE K+
Sbjct: 548 MKQEFLINLVKQKPQITEEQLEAVIADFSGLLEKCCQGQEQEVCFAEEGQKL 599
Score = 110 bits (274), Expect = 5e-24
Identities = 78/409 (19%), Positives = 169/409 (41%), Gaps = 17/409 (4%)
Query: 15 FLTESLTLPTQPRDIENFNS-----TQKFIEDNIEYITIIAFAQYVQEATFEEMEKLVKD 69
F T++ T+ + R+ N + F + IT+ +Q + F E++KLV D
Sbjct: 202 FQTKAATVTKELRESSLLNQHACAVMKNFGTRTFQAITVTKLSQKFTKVNFTEIQKLVLD 261
Query: 70 MVEYKDRCMADKTLPECSKLPNNVLQEKICAMEGLPQKHNFSHCCSKVDAQRRLCFFY-- 127
+ + C L +C + ++ + L K + CC +R C +
Sbjct: 262 VAHVHEHCCRGDVL-DCLQDGEKIMSYICSQQDTLSNK--ITECCKLTTLERGQCIIHAE 318
Query: 128 NKKSDVGFLPPFPTLDPEEKCQAYESNRESL-LNHFLYEVARRNPFVFAPTLLTVAVHFE 186
N + G P + + S +++ L F++E +RR+P + +L VA ++
Sbjct: 319 NDEKPEGLSPNLNRFLGDRDFNQFSSGEKNIFLASFVHEYSRRHPQLAVSVILRVAKGYQ 378
Query: 187 EVAKSCCEEQNKVNCLQTRAIPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIYIAILSQK 246
E+ + C + +N + C + +Y++ + K CG K G + ++ ++K
Sbjct: 379 ELLEKCFQTENPLECQDKGEEELQKYIQESQALAKRSCGLFQKLGEYYLQNAFLVAYTKK 438
Query: 247 FPKIEFKELISLVEDVSSNYDGCC---EGDVVQCIRDTSKVM-NHICSKQDS--ISSKIK 300
P++ EL+++ +++ CC E ++ C + ++ H+C + + ++ +
Sbjct: 439 APQLTSSELMAITRKMAATAATCCQLSEDKLLACGEGAADIIIGHLCIRHEMTPVNPGVG 498
Query: 301 ECCEKKIPERGQCIINSNKDDRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSR 360
+CC R C + D+ + + KF +++CQ + T +F +
Sbjct: 499 QCCTSSYANRRPCFSSLVVDETYVPPAFSDDKFIFHKDLCQAQGVALQTMKQEFLINLVK 558
Query: 361 RHPDLSIPELLRIVQIYKDLLRNCCNTENPPGCYRYAEDKFNETTEKSL 409
+ P ++ +L ++ + LL CC + C+ K T +L
Sbjct: 559 QKPQITEEQLEAVIADFSGLLEKCCQGQEQEVCFAEEGQKLISKTRAAL 607
>gi|4502027 albumin preproprotein [Homo sapiens]
Length = 609
Score = 412 bits (1060), Expect = e-115
Identities = 211/600 (35%), Positives = 327/600 (54%), Gaps = 7/600 (1%)
Query: 4 LKLTGFIFFLFFLTESLTLPTQPRDIENFNSTQKFI---EDNIEYITIIAFAQYVQEATF 60
+K FI LF + + + RD +F E+N + + +IAFAQY+Q+ F
Sbjct: 1 MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPF 60
Query: 61 EEMEKLVKDMVEYKDRCMADKTLPECSKLPNNVLQEKICAMEGLPQKHN-FSHCCSKVDA 119
E+ KLV ++ E+ C+AD++ C K + + +K+C + L + + + CC+K +
Sbjct: 61 EDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEP 120
Query: 120 QRRLCFFYNKKSDVGFLPPFPTLDPEEKCQAYESNRESLLNHFLYEVARRNPFVFAPTLL 179
+R CF +K + LP + + C A+ N E+ L +LYE+ARR+P+ +AP LL
Sbjct: 121 ERNECFLQHKDDNPN-LPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELL 179
Query: 180 TVAVHFEEVAKSCCEEQNKVNCLQTRAIPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIY 239
A ++ CC+ +K CL + + KA S+ Q+ C +L KFG +
Sbjct: 180 FFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWA 239
Query: 240 IAILSQKFPKIEFKELISLVEDVSSNYDGCCEGDVVQCIRDTSKVMNHICSKQDSISSKI 299
+A LSQ+FPK EF E+ LV D++ + CC GD+++C D + + +IC QDSISSK+
Sbjct: 240 VARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKL 299
Query: 300 KECCEKKIPERGQCIINSNKDDRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYS 359
KECCEK + E+ CI D+ P DL F +S++VC+ D F F +EY+
Sbjct: 300 KECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYA 359
Query: 360 RRHPDLSIPELLRIVQIYKDLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHF 419
RRHPD S+ LLR+ + Y+ L CC +P CY D+F E+ +++Q C+ F
Sbjct: 360 RRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELF 419
Query: 420 QNLGKDGLKYHYLIRLTKIAPQLSTEELVSLGEKMVTAFTTCCTLSE--EFACVDNLADL 477
+ LG+ + L+R TK PQ+ST LV + + + CC E C ++ +
Sbjct: 420 EQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSV 479
Query: 478 VFGELCGVNENRTINPAVDHCCKTNFAFRRPCFESLKADKTYVPPPFSQDLFTFHADMCQ 537
V +LC ++E ++ V CC + RRPCF +L+ D+TYVP F+ + FTFHAD+C
Sbjct: 480 VLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICT 539
Query: 538 SQNEELQRKTDRFLVNLVKLKHELTDEELQSLFTNFANVVDKCCKAESPEVCFNEESPKI 597
+E Q K LV LVK K + T E+L+++ +FA V+KCCKA+ E CF EE K+
Sbjct: 540 LSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKL 599
>gi|32483410 vitamin D-binding protein precursor [Homo sapiens]
Length = 474
Score = 120 bits (302), Expect = 3e-27
Identities = 95/447 (21%), Positives = 185/447 (41%), Gaps = 19/447 (4%)
Query: 27 RDIENFNSTQKFI---EDNIEYITIIAFAQYVQEATFEEMEKLVKDMVEYKDRCMADKTL 83
RD E ++F +++ ++++ +++ TFE++ +LVK++V + C A+
Sbjct: 21 RDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGAD 80
Query: 84 PECSKLPNNVLQEKICAMEG-LPQKHNFSHCCSKVDAQRRLCFFYNKKSDVGFLPPFPTL 142
P+C + L K C P + CC+K +R+LC K F P +
Sbjct: 81 PDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEF-PTYVEP 139
Query: 143 DPEEKCQAYESNRESLLNHFLYEVARRNPFVFAPTLLTVAVHFEEVAKSCCEEQNKVNCL 202
+E C+A+ + + N F++E + L++ + + SCC + C
Sbjct: 140 TNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCF 199
Query: 203 QTRAIPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIYIAILSQKFPKIEFKELISLVEDV 262
+ + ++L ++ VC +G K + L+QK P + ++++ L ED+
Sbjct: 200 LKERLQL-KHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDI 258
Query: 263 SSNYDGCCEGDVVQCI-RDTSKVMNHICSKQDSISSKIKECC-EKKIPERGQCIINSNKD 320
++ CCE C+ ++ + +C + +SK ++CC EK + C
Sbjct: 259 TNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAA 318
Query: 321 DRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSRRHPDLSIPE--LLRIVQIYK 378
P+ L + + +++VC D K+TFE SRR +PE L ++++
Sbjct: 319 QLPE---LPDVELPTNKDVC---DPGNTKVMDKYTFELSRR---THLPEVFLSKVLEPTL 369
Query: 379 DLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQNLGKDGLKYHYLIRLTKI 438
L CC+ E+ C+ + + Q+ C + K RL
Sbjct: 370 KSLGECCDVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAK 429
Query: 439 APQLSTEELVSLGEKMVTAFTTCCTLS 465
P + EL L K + CC+++
Sbjct: 430 LPDATPTELAKLVNKHSDFASNCCSIN 456
Score = 86.3 bits (212), Expect = 7e-17
Identities = 82/396 (20%), Positives = 159/396 (40%), Gaps = 21/396 (5%)
Query: 206 AIPVTQYLKAFSSYQKH-VCGALLKFGTKVVHFIYIAILSQKFPKIEFKELISLVEDVSS 264
A+ L+ Y+K+ VC G + + + + S+KFP F+++ LV++V S
Sbjct: 10 AVAFGHALERGRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVS 69
Query: 265 NYDGCC-EGDVVQCIRDTSKVMNHICSKQDS---ISSKIKECCEKKIPERGQCIINSNKD 320
+ CC EG C + ++ + +S + ECC K+ ER C+ +
Sbjct: 70 LTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCM--AALK 127
Query: 321 DRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSRRHPDLSIPELLRIVQIYKDL 380
+P++ D +C+ DP + +F +EYS + + L+ + Y +
Sbjct: 128 HQPQEFPTYVEPTNDE--ICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSM 185
Query: 381 LRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQNLGKDGLKYHYLIRLTKIAP 440
+ +CC + +P C+ + + + + + C + G+ + LI+L + P
Sbjct: 186 VGSCCTSASPTVCFLKERLQLKHLSLLTT-LSNRVCSQYAAYGEKKSRLSNLIKLAQKVP 244
Query: 441 QLSTEELVSLGEKMVTAFTTCCTLSEEFACVDNLADLVFGELCGVNENRTINPAVDHCCK 500
E+++ L E + + CC + E L + +LC + T N + CC+
Sbjct: 245 TADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTV-KLC--DNLSTKNSKFEDCCQ 301
Query: 501 TNFAFRR-PCFESLKADKTYVPPPFSQDLFTFHADMCQSQNEELQRKTDRFLVNLVKLKH 559
A C + A + P + D+C N ++ D++ L + H
Sbjct: 302 EKTAMDVFVCTYFMPAAQL---PELPDVELPTNKDVCDPGNTKVM---DKYTFELSRRTH 355
Query: 560 ELTDEELQSLFTNFANVVDKCCKAESPEVCFNEESP 595
L + L + + +CC E CFN + P
Sbjct: 356 -LPEVFLSKVLEPTLKSLGECCDVEDSTTCFNAKGP 390
Score = 40.0 bits (92), Expect = 0.006
Identities = 75/359 (20%), Positives = 134/359 (37%), Gaps = 50/359 (13%)
Query: 51 FAQYVQEATFEEMEKLVKDMVEYKDRCMADKTLPECSKLPNNVL---QEKICAMEGLPQK 107
F YV+ E E KD EY ++ M + + + P ++L + +M G
Sbjct: 133 FPTYVEPTNDEICEAFRKDPKEYANQFMWEYST-NYGQAPLSLLVSYTKSYLSMVG---- 187
Query: 108 HNFSHCCSKVDAQRRLCFFYNKKSDVGFLPPFPTLDPEEKCQ--AYESNRESLLNHFLYE 165
CC+ A +CF ++ + L TL Q AY + L N L +
Sbjct: 188 ----SCCTS--ASPTVCFL-KERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSN--LIK 238
Query: 166 VARRNPFVFAPTLLTVAVHFEEVAKSCCEEQNKVNC----LQTRAIPVTQYLKAFSSYQK 221
+A++ P +L +A + CCE ++ +C L + + L +S +
Sbjct: 239 LAQKVPTADLEDVLPLAEDITNILSKCCESASE-DCMAKELPEHTVKLCDNLSTKNSKFE 297
Query: 222 HVCGALLKFGTKVVHFIYIAILSQKFPKIEFKELISLVEDVSSNYDGCCEGDVVQCIRDT 281
C V + A + P +E + +N D C G+ + T
Sbjct: 298 DCCQEKTAMDVFVCTYFMPAAQLPELPDVE----------LPTNKDVCDPGNTKVMDKYT 347
Query: 282 SKVMNHICSKQDSISSKIK-------ECCEKKIPERGQCIINSNKDDRPKDLSLREGKFT 334
++ + +S ++ ECC+ E N+ K+LS F
Sbjct: 348 FELSRRTHLPEVFLSKVLEPTLKSLGECCDV---EDSTTCFNAKGPLLKKELS----SFI 400
Query: 335 DS-ENVCQERDADPDTFFAKFTFEYSR-RHPDLSIPELLRIVQIYKDLLRNCCNTENPP 391
D + +C + + T + K E + + PD + EL ++V + D NCC+ +PP
Sbjct: 401 DKGQELCADYSENTFTEYKKKLAERLKAKLPDATPTELAKLVNKHSDFASNCCSINSPP 459
>gi|15559209 interleukin 33 [Homo sapiens]
Length = 270
Score = 32.3 bits (72), Expect = 1.3
Identities = 48/202 (23%), Positives = 78/202 (38%), Gaps = 43/202 (21%)
Query: 176 PTLLTVAVHFEEVAKSCCEEQNKVNCL---------QTRAI---------PVTQYLKAFS 217
P+L T H + + C++Q+ V C TRA+ P+T+YL + S
Sbjct: 68 PSLKTGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSSITGISPITEYLASLS 127
Query: 218 SYQKHVCGALLKFGTKVVHFIYIAILSQKFPKIEFKELISLVED---VSSNYDGCCEGDV 274
+Y L+ + + IY+ L + K K L+S E + + DG +
Sbjct: 128 TYNDQSITFALEDES---YEIYVEDLKKDEKK--DKVLLSYYESQHPSNESGDGVDGKML 182
Query: 275 VQCIRDTSKVMNHICSKQDSISSKIKECCEKKIPER---------GQCIINSNKDD---- 321
+ + T H +K+ S+ CEK +P++ C+ K D
Sbjct: 183 MVTLSPTKDFWLHANNKEHSVE---LHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVF 239
Query: 322 -RPKDLSLREGKFTDSENVCQE 342
KD L K SEN+C E
Sbjct: 240 IGVKDNHLALIKVDSSENLCTE 261
>gi|148664238 a disintegrin and metalloprotease domain 32 [Homo
sapiens]
Length = 787
Score = 32.0 bits (71), Expect = 1.7
Identities = 51/230 (22%), Positives = 81/230 (35%), Gaps = 37/230 (16%)
Query: 179 LTVAVHFEEVAKSCCEEQNKVNCLQTRAIPVTQYLKAFSSYQ-KHVCGALLKFGTKVVHF 237
L++ + +++ K C E C+ + + +K FSS + + G K +
Sbjct: 325 LSLGISYDDPKKCQCSEST---CIMNPEVVQSNGVKTFSSCSLRSFQNFISNVGVKCLQ- 380
Query: 238 IYIAILSQKFPK-------IEFKELISLVEDVSSNYDGCCEGDVVQCI-RDTSKVMNHIC 289
+ +K PK +E E+ + CC D C+ +D +K +C
Sbjct: 381 -NKPQMQKKSPKPVCGNGRLEGNEICDCGTEAQCGPASCC--DFRTCVLKDGAKCYKGLC 437
Query: 290 SKQDSISSKIKECCEKKIPERGQCIINSNKDDRPKD----------LSLREGKFTDSENV 339
K I EC K PE C I N + + LS + KF +
Sbjct: 438 CKDCQILQSGVECRPKAHPE---CDIAENCNGSSPECGPDITLINGLSCKNNKFICYDGD 494
Query: 340 CQERDADPDTFFAKFTFEYSRRHPDLSIPELLRIVQIYKDLLRNCCNTEN 389
C + DA ++ F K SR P E +Q D NC N
Sbjct: 495 CHDLDARCESVFGK----GSRNAPFACYEE----IQSQSDRFGNCGRDRN 536
>gi|113722133 senataxin [Homo sapiens]
Length = 2677
Score = 31.6 bits (70), Expect = 2.2
Identities = 26/116 (22%), Positives = 48/116 (41%), Gaps = 12/116 (10%)
Query: 293 DSISSKIKECCEKKIPERGQCIINSNKDDRPKDLSLREG--KFTDSENVCQERDADPDTF 350
+ ++ + K C E++ PE+ +NS ++ P E +F +S++ C E ++ +
Sbjct: 1031 EKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQCFEFESSSE-- 1088
Query: 351 FAKFTFEYSRRHPDLSIPELLRIVQIYKDLLRNCCNTENPPGCYRYAEDKFNETTE 406
F + HPD + + K L NT N GC Y + + E
Sbjct: 1089 ----VFSVWQDHPD----DNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAE 1136
>gi|62460637 importin 4 [Homo sapiens]
Length = 1081
Score = 31.6 bits (70), Expect = 2.2
Identities = 19/52 (36%), Positives = 28/52 (53%), Gaps = 3/52 (5%)
Query: 422 LGKDGLKYHYLIRLTKIAPQLSTEELV---SLGEKMVTAFTTCCTLSEEFAC 470
+G GL ++ L LT +AP LSTE++ L K++ A T + E AC
Sbjct: 171 VGSPGLLFYSLRTLTTMAPYLSTEDVPLARMLVPKLIMAMQTLIPIDEAKAC 222
>gi|41152093 zinc finger protein 644 isoform 1 [Homo sapiens]
Length = 1327
Score = 31.6 bits (70), Expect = 2.2
Identities = 22/50 (44%), Positives = 28/50 (56%), Gaps = 3/50 (6%)
Query: 539 QNEELQRKTDRFLVNLVKLKHELTDEELQSL--FTNFANVVDKCCKAESP 586
QNEELQ D L K+K E TDE+L+S+ F + DKC + SP
Sbjct: 328 QNEELQA-VDSQKYALSKVKPESTDEDLESVDAFQHLIYNPDKCGEESSP 376
>gi|4826730 FK506 binding protein 12-rapamycin associated protein 1
[Homo sapiens]
Length = 2549
Score = 31.2 bits (69), Expect = 2.8
Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 7/65 (10%)
Query: 398 EDKFNETTEKSLKMVQQECKHFQNLG--KD-----GLKYHYLIRLTKIAPQLSTEELVSL 450
E FN+ + L Q+ C+ + G KD L YH R++K PQL++ EL +
Sbjct: 2067 ETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYV 2126
Query: 451 GEKMV 455
K++
Sbjct: 2127 SPKLL 2131
>gi|227430327 calsequestrin 1 [Homo sapiens]
Length = 396
Score = 30.8 bits (68), Expect = 3.7
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 17/80 (21%)
Query: 4 LKLTGFIFFLFFLTESLTLPTQPR---DIENF--------------NSTQKFIEDNIEYI 46
LKL F+ F+ E +T+P +P +I NF S + ED+++ I
Sbjct: 224 LKLNEIDFYEAFMEEPVTIPDKPNSEEEIVNFVEEHRRSTLRKLKPESMYETWEDDMDGI 283
Query: 47 TIIAFAQYVQEATFEEMEKL 66
I+AFA+ FE +E L
Sbjct: 284 HIVAFAEEADPDGFEFLETL 303
>gi|38708169 sorting nexin 25 [Homo sapiens]
Length = 840
Score = 30.8 bits (68), Expect = 3.7
Identities = 35/139 (25%), Positives = 59/139 (42%), Gaps = 17/139 (12%)
Query: 300 KECCEKKIPERGQCIINSNKDDRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYS 359
K+ CEK+I I+ D+ +D +L EG+ S+ + Q D +TF+ + Y
Sbjct: 251 KKQCEKRIR-----ILGGPAYDQQEDGALDEGEGPQSQKILQFEDILANTFYREHFGMYM 305
Query: 360 RRHPDLSIPELLRIVQIYKDLLRNCCNTENPPGCYRYAEDKFNE----TTEKSLKMVQQE 415
R ++ V + L+N E P ++ F E + EKSL Q+
Sbjct: 306 ERMDKRALISFWESV----EHLKNANKNEIPQLVGEIYQNFFVESKEISVEKSLYKEIQQ 361
Query: 416 CKHFQNLGKDGLKYHYLIR 434
C +G G++ Y I+
Sbjct: 362 CL----VGNKGIEVFYKIQ 376
>gi|239744397 PREDICTED: hypothetical protein LOC100130348 [Homo
sapiens]
Length = 153
Score = 30.0 bits (66), Expect = 6.3
Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 5/82 (6%)
Query: 2 KLLKLTGFIFFLFFLTESLTLPTQPRDIENFNSTQKFIEDNIEYITIIAFAQYVQEATFE 61
K + LT LFFL + + RD+ NF T + + Y ++ F+Q + +
Sbjct: 14 KGMMLTTAALMLFFLHLGIFI----RDVHNFCITYHYDHMSFHYTVVLMFSQVI-SICWA 68
Query: 62 EMEKLVKDMVEYKDRCMADKTL 83
M L +M E K C + T+
Sbjct: 69 AMGSLYAEMTENKYVCFSALTI 90
>gi|239787094 A20-binding inhibitor of NF-kappaB activation 2
isoform 2 [Homo sapiens]
Length = 322
Score = 29.6 bits (65), Expect = 8.3
Identities = 20/87 (22%), Positives = 45/87 (51%), Gaps = 5/87 (5%)
Query: 20 LTLPTQP----RDIENFN-STQKFIEDNIEYITIIAFAQYVQEATFEEMEKLVKDMVEYK 74
L +P +P ++I N ++ I D E +A ++ ++A E ++ L + ++ YK
Sbjct: 141 LQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAYK 200
Query: 75 DRCMADKTLPECSKLPNNVLQEKICAM 101
D M+++ E ++ L+EK+ ++
Sbjct: 201 DDFMSERADRERAQSRIQELEEKVASL 227
>gi|239787092 A20-binding inhibitor of NF-kappaB activation 2
isoform 1 [Homo sapiens]
Length = 429
Score = 29.6 bits (65), Expect = 8.3
Identities = 20/87 (22%), Positives = 45/87 (51%), Gaps = 5/87 (5%)
Query: 20 LTLPTQP----RDIENFN-STQKFIEDNIEYITIIAFAQYVQEATFEEMEKLVKDMVEYK 74
L +P +P ++I N ++ I D E +A ++ ++A E ++ L + ++ YK
Sbjct: 248 LQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAYK 307
Query: 75 DRCMADKTLPECSKLPNNVLQEKICAM 101
D M+++ E ++ L+EK+ ++
Sbjct: 308 DDFMSERADRERAQSRIQELEEKVASL 334
>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
Length = 4523
Score = 29.6 bits (65), Expect = 8.3
Identities = 37/150 (24%), Positives = 60/150 (40%), Gaps = 31/150 (20%)
Query: 143 DPEEKCQAY-ESNRESLLNHFLYEVARRNPFVFAPTLLTVAVHFEEVAKS---CCEEQNK 198
D E K QA ++N E E R+ L + FE+ C EE N+
Sbjct: 3319 DVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTASFEKATAEKVRCQEEVNQ 3378
Query: 199 VNC-----------LQTRAIPVTQYLKAFSSYQKHVCGALL--------------KFGTK 233
N L+ + I Q +K+F + +K +CG +L ++ +
Sbjct: 3379 TNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVGPFTRQYRQE 3438
Query: 234 VVHFIYIAILSQK--FPKIEFKELISLVED 261
+VH ++ L QK P E +LIS++ D
Sbjct: 3439 LVHCKWVPFLQQKVSIPLTEGLDLISMLTD 3468
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,588,886
Number of Sequences: 37866
Number of extensions: 1094906
Number of successful extensions: 2702
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2638
Number of HSP's gapped (non-prelim): 26
length of query: 599
length of database: 18,247,518
effective HSP length: 108
effective length of query: 491
effective length of database: 14,157,990
effective search space: 6951573090
effective search space used: 6951573090
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.