Guide to the Human Genome
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Search of human proteins with 42794612

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42794612 myeloma overexpressed [Homo sapiens]
         (313 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42794612 myeloma overexpressed [Homo sapiens]                      646   0.0  
gi|62988346 glutamate receptor, ionotropic, N-methyl-D-aspartate...    33   0.43 
gi|189571583 intercellular adhesion molecule 5 precursor [Homo s...    31   1.2  
gi|18087849 solute carrier family 35, member A4 [Homo sapiens]         31   1.2  
gi|169169847 PREDICTED: hypothetical protein [Homo sapiens]            30   2.1  
gi|51593088 neuroligin 3 [Homo sapiens]                                30   2.8  
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]            30   3.6  
gi|240255430 hypothetical protein LOC100289135 [Homo sapiens]          29   6.2  
gi|239754604 PREDICTED: similar to hCG1802898 [Homo sapiens]           29   6.2  
gi|239749150 PREDICTED: hypothetical protein XP_002346928 [Homo ...    29   6.2  
gi|113420249 PREDICTED: hypothetical protein LOC728071 [Homo sap...    29   6.2  
gi|31317256 X-linked neuroligin 4 [Homo sapiens]                       29   6.2  
gi|24308209 X-linked neuroligin 4 [Homo sapiens]                       29   6.2  
gi|13124773 brain protein 16 [Homo sapiens]                            29   6.2  
gi|239755238 PREDICTED: hypothetical protein [Homo sapiens]            28   8.0  
gi|239749762 PREDICTED: hypothetical protein XP_002347151 [Homo ...    28   8.0  
gi|239744021 PREDICTED: hypothetical protein XP_002343019 [Homo ...    28   8.0  
gi|95147555 microtubule-associated protein 1A [Homo sapiens]           28   8.0  
gi|82546830 SEC8 protein isoform a [Homo sapiens]                      28   8.0  
gi|150378452 heparan-alpha-glucosaminide N-acetyltransferase [Ho...    28   8.0  

>gi|42794612 myeloma overexpressed [Homo sapiens]
          Length = 313

 Score =  646 bits (1667), Expect = 0.0
 Identities = 313/313 (100%), Positives = 313/313 (100%)

Query: 1   MALRICVTYTPALPIGLCTRCCLCLEQSPSWCHCLRGVSFLTFHLHQSVPLGDRDSLLMF 60
           MALRICVTYTPALPIGLCTRCCLCLEQSPSWCHCLRGVSFLTFHLHQSVPLGDRDSLLMF
Sbjct: 1   MALRICVTYTPALPIGLCTRCCLCLEQSPSWCHCLRGVSFLTFHLHQSVPLGDRDSLLMF 60

Query: 61  TRQAGHFVEGSKAGRSRGRLCLSQALRVAVRGAFVSLWFAAGAGDRERNKGDKGAQTGAG 120
           TRQAGHFVEGSKAGRSRGRLCLSQALRVAVRGAFVSLWFAAGAGDRERNKGDKGAQTGAG
Sbjct: 61  TRQAGHFVEGSKAGRSRGRLCLSQALRVAVRGAFVSLWFAAGAGDRERNKGDKGAQTGAG 120

Query: 121 LSQEAEDVDVSRARRVTDAPQGTLCGTGNRNSGSQSARVVGVAHLGEAFRVGVEQAISSC 180
           LSQEAEDVDVSRARRVTDAPQGTLCGTGNRNSGSQSARVVGVAHLGEAFRVGVEQAISSC
Sbjct: 121 LSQEAEDVDVSRARRVTDAPQGTLCGTGNRNSGSQSARVVGVAHLGEAFRVGVEQAISSC 180

Query: 181 PEEVHGRHGLSMEIMWARMDVALRSPGRGLLAGAGALCMTLAESSCPDYERGRRACLTLH 240
           PEEVHGRHGLSMEIMWARMDVALRSPGRGLLAGAGALCMTLAESSCPDYERGRRACLTLH
Sbjct: 181 PEEVHGRHGLSMEIMWARMDVALRSPGRGLLAGAGALCMTLAESSCPDYERGRRACLTLH 240

Query: 241 RHPTPHCSTWGLPLRVAGSWLTVVTVEALGGWRMGVRRTGQVGPTMHPPPVSGASPLLLH 300
           RHPTPHCSTWGLPLRVAGSWLTVVTVEALGGWRMGVRRTGQVGPTMHPPPVSGASPLLLH
Sbjct: 241 RHPTPHCSTWGLPLRVAGSWLTVVTVEALGGWRMGVRRTGQVGPTMHPPPVSGASPLLLH 300

Query: 301 HLLLLLLIIILTC 313
           HLLLLLLIIILTC
Sbjct: 301 HLLLLLLIIILTC 313


>gi|62988346 glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
           [Homo sapiens]
          Length = 1043

 Score = 32.7 bits (73), Expect = 0.43
 Identities = 53/179 (29%), Positives = 70/179 (39%), Gaps = 21/179 (11%)

Query: 129 DVSRARRVTDA-PQGT--LCGTGNRNSGSQSARVV-GVAHLGEAFRVGVEQAISSCPEEV 184
           D++RARRV +A P G   L GT        +A +  G+  LGE  R  +E AI    + V
Sbjct: 241 DIARARRVLEAVPPGPHWLLGTPLPPKALPTAGLPPGLLALGEVARPPLEAAIHDIVQLV 300

Query: 185 HGRHGLSMEIMWARMDVALRSPGR-GLLAGAGA------LCMTLAESSCPDYERGRRACL 237
               G + ++   R    L +P   G L  AG       L   LA +S            
Sbjct: 301 ARALGSAAQVQPKR--ALLPAPVNCGDLQPAGPESPGRFLARFLANTSFQGRTGPVWVTG 358

Query: 238 TLHRHPTPHCSTWGLPL--RVAGSWLTVVTVEALGGWRMGVRRTGQVGPTMHPPPVSGA 294
           +   H + H   W L    R A +W TV      G WR G       G +  PPP  GA
Sbjct: 359 SSQVHMSRHFKVWSLRRDPRGAPAWATV------GSWRDGQLDLEPGGASARPPPPQGA 411


>gi|189571583 intercellular adhesion molecule 5 precursor [Homo
           sapiens]
          Length = 924

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 36/155 (23%), Positives = 56/155 (36%), Gaps = 10/155 (6%)

Query: 120 GLSQEAEDVDVSRARRVTDAPQGTLCGTGNRNSGSQSARVVGVAHLGEAFRVGVEQAISS 179
           G+    E +     +RV+    GT         G+ S  V     +G  +R  V +  +S
Sbjct: 699 GVRCSREGIPWPEQQRVSREDAGTYHCVATNAHGTDSRTVT----VGVEYRPVVAELAAS 754

Query: 180 CPEEVHGRHGLSMEIM---WARMDVALRSPGRGLLAGAGALCMTLAESSCPDYERGRRAC 236
            P  V      ++      W    ++ R+P   L  G  +   TL+ +       G   C
Sbjct: 755 PPGGVRPGGNFTLTCRAEAWPPAQISWRAPPGALNIGLSSNNSTLSVAGAMGSHGGEYEC 814

Query: 237 LTLHRHPTPHCSTWGLPLRVAGSWLTVVTVEALGG 271
              + H   H     + +RVAG WL V    A GG
Sbjct: 815 AATNAHGR-HARR--ITVRVAGPWLWVAVGGAAGG 846


>gi|18087849 solute carrier family 35, member A4 [Homo sapiens]
          Length = 324

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 17/39 (43%), Positives = 24/39 (61%), Gaps = 2/39 (5%)

Query: 275 GVRRTGQVGPTMHPPPVSGASPLLLHHLLLLLLIIILTC 313
           G++  G   P+  PPP + ASP+ LH   L LL++IL C
Sbjct: 160 GLQVPGNTLPS--PPPAAAASPMPLHITPLGLLLLILYC 196


>gi|169169847 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 295

 Score = 30.4 bits (67), Expect = 2.1
 Identities = 54/225 (24%), Positives = 79/225 (35%), Gaps = 32/225 (14%)

Query: 44  HLHQSVPLGDRDSLLMFTRQAGHFVEGSKAGRSRGRLCLSQA-------LRVAVRGAFVS 96
           H+H  + L  +DS L +T         S AG   G+  +  A       L     G  V 
Sbjct: 14  HVHWYLQLLWKDSPLRYTVPPKMQGAPSLAGEEEGKRGVGDAEVRHWGTLTSRASGMRVG 73

Query: 97  LWFAAG----AGDRERNKGDKGAQTGAGLSQEAEDVDVSRARRVTDAPQGTLCGTGNRNS 152
           +W A G    AG+R   +    +    G+ +EA       A  +T A      G G   +
Sbjct: 74  IWAAGGGLAAAGERNSVRAVSFSSGRVGVREEAAGHLAVGAAGLTGAHADLAVGRGAEVT 133

Query: 153 GSQSARVVGVAHLGE--AFRVGVEQAISSCPE-EVHGRHGLSMEIMWARMDVALRSPGRG 209
                RV GVA LG   A  +G + A ++  + E H R                R+  R 
Sbjct: 134 EEALVRVAGVA-LGAQLAQLLGADAAAAAAVQHEAHAR----------------RTARRW 176

Query: 210 LLAGAGALCMTLAESSCPDYERGRRACLTLHRHP-TPHCSTWGLP 253
           L+         LA+      + G+R  +  H  P  P    W  P
Sbjct: 177 LVRAPARPAAVLADGRLQGGQGGQRRSVGAHALPGRPRVPPWQPP 221


>gi|51593088 neuroligin 3 [Homo sapiens]
          Length = 828

 Score = 30.0 bits (66), Expect = 2.8
 Identities = 33/107 (30%), Positives = 49/107 (45%), Gaps = 9/107 (8%)

Query: 124 EAEDVDVSRARRVTDAPQGT--LCGTGNRNSGSQSARVVGVAHLGEAFRVGVEQAISSCP 181
           E ED+  S A+ V     G   + GTGN   GS  A    V  +   +RVGV   +S+  
Sbjct: 170 EDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGD 229

Query: 182 EEVHGRHGLSMEIM---WARMDVAL--RSPGRGLL--AGAGALCMTL 221
           +   G +GL  +I    W   ++A     P R  +  +G GA C++L
Sbjct: 230 QAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSL 276


>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 819

 Score = 29.6 bits (65), Expect = 3.6
 Identities = 26/95 (27%), Positives = 37/95 (38%), Gaps = 3/95 (3%)

Query: 71  SKAGRSRG---RLCLSQALRVAVRGAFVSLWFAAGAGDRERNKGDKGAQTGAGLSQEAED 127
           S+ G+SRG   +    Q    A+ GA       AG     + +G +G ++  G +     
Sbjct: 261 SRVGKSRGGGDKKLRRQGQNAALAGAKRRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGR 320

Query: 128 VDVSRARRVTDAPQGTLCGTGNRNSGSQSARVVGV 162
                 RR   A +    GT     G Q A VVGV
Sbjct: 321 GGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGV 355


>gi|240255430 hypothetical protein LOC100289135 [Homo sapiens]
          Length = 215

 Score = 28.9 bits (63), Expect = 6.2
 Identities = 16/42 (38%), Positives = 20/42 (47%)

Query: 253 PLRVAGSWLTVVTVEALGGWRMGVRRTGQVGPTMHPPPVSGA 294
           P++ AGS  T V          G RR G +GP   PP  +GA
Sbjct: 134 PVQDAGSEATSVVARDPSQDLPGTRRDGTLGPRPQPPAAAGA 175


>gi|239754604 PREDICTED: similar to hCG1802898 [Homo sapiens]
          Length = 229

 Score = 28.9 bits (63), Expect = 6.2
 Identities = 16/42 (38%), Positives = 20/42 (47%)

Query: 253 PLRVAGSWLTVVTVEALGGWRMGVRRTGQVGPTMHPPPVSGA 294
           P++ AGS  T V          G RR G +GP   PP  +GA
Sbjct: 148 PVQDAGSEATSVVARDPSQDLPGTRRDGTLGPRPQPPAAAGA 189


>gi|239749150 PREDICTED: hypothetical protein XP_002346928 [Homo
           sapiens]
          Length = 229

 Score = 28.9 bits (63), Expect = 6.2
 Identities = 16/42 (38%), Positives = 20/42 (47%)

Query: 253 PLRVAGSWLTVVTVEALGGWRMGVRRTGQVGPTMHPPPVSGA 294
           P++ AGS  T V          G RR G +GP   PP  +GA
Sbjct: 148 PVQDAGSEATSVVARDPSQDLPGTRRDGTLGPRPQPPAAAGA 189


>gi|113420249 PREDICTED: hypothetical protein LOC728071 [Homo
           sapiens]
          Length = 390

 Score = 28.9 bits (63), Expect = 6.2
 Identities = 24/60 (40%), Positives = 29/60 (48%), Gaps = 8/60 (13%)

Query: 206 PGRGLLAGAGAL---CMTLAESSCPDYERGRRACLTLHRHPTPH----CSTWGLPLRVAG 258
           PGR LLAG  AL    M LA +S P  +   RA + L   P  H     +  GLP R+ G
Sbjct: 53  PGRALLAGQAALLQALMELAPASAPARD-AARALVNLAADPGLHETLLAADPGLPARLMG 111


>gi|31317256 X-linked neuroligin 4 [Homo sapiens]
          Length = 816

 Score = 28.9 bits (63), Expect = 6.2
 Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 146 GTGNRNSGSQSARVVGVAHLGEAFRVGVEQAISSCPEEVHGRHGLSMEIM---WARMDVA 202
           GTGN   GS  A    V  +   +R+G+   +S+  +   G +GL  +I    W   +V 
Sbjct: 180 GTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVG 239

Query: 203 L--RSPGRGLL--AGAGALCMTL 221
                P R  +  +GAGA C++L
Sbjct: 240 AFGGDPKRVTIFGSGAGASCVSL 262


>gi|24308209 X-linked neuroligin 4 [Homo sapiens]
          Length = 816

 Score = 28.9 bits (63), Expect = 6.2
 Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 146 GTGNRNSGSQSARVVGVAHLGEAFRVGVEQAISSCPEEVHGRHGLSMEIM---WARMDVA 202
           GTGN   GS  A    V  +   +R+G+   +S+  +   G +GL  +I    W   +V 
Sbjct: 180 GTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVG 239

Query: 203 L--RSPGRGLL--AGAGALCMTL 221
                P R  +  +GAGA C++L
Sbjct: 240 AFGGDPKRVTIFGSGAGASCVSL 262


>gi|13124773 brain protein 16 [Homo sapiens]
          Length = 390

 Score = 28.9 bits (63), Expect = 6.2
 Identities = 24/60 (40%), Positives = 29/60 (48%), Gaps = 8/60 (13%)

Query: 206 PGRGLLAGAGAL---CMTLAESSCPDYERGRRACLTLHRHPTPH----CSTWGLPLRVAG 258
           PGR LLAG  AL    M LA +S P  +   RA + L   P  H     +  GLP R+ G
Sbjct: 53  PGRALLAGQAALLQALMELAPASAPARD-AARALVNLAADPGLHETLLAADPGLPARLMG 111


>gi|239755238 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 142

 Score = 28.5 bits (62), Expect = 8.0
 Identities = 22/55 (40%), Positives = 24/55 (43%), Gaps = 2/55 (3%)

Query: 247 CSTWGLPLR--VAGSWLTVVTVEALGGWRMGVRRTGQVGPTMHPPPVSGASPLLL 299
           C+  G PL    A  WL    V AL G   G   TGQ GP    P  SG+  L L
Sbjct: 62  CAFAGRPLIDVKASGWLRRSPVGALPGAGFGAHATGQRGPHGATPLFSGSLGLQL 116


>gi|239749762 PREDICTED: hypothetical protein XP_002347151 [Homo
           sapiens]
          Length = 142

 Score = 28.5 bits (62), Expect = 8.0
 Identities = 22/55 (40%), Positives = 24/55 (43%), Gaps = 2/55 (3%)

Query: 247 CSTWGLPLR--VAGSWLTVVTVEALGGWRMGVRRTGQVGPTMHPPPVSGASPLLL 299
           C+  G PL    A  WL    V AL G   G   TGQ GP    P  SG+  L L
Sbjct: 62  CAFAGRPLIDVKASGWLRRSPVGALPGAGFGAHATGQRGPHGATPLFSGSLGLQL 116


>gi|239744021 PREDICTED: hypothetical protein XP_002343019 [Homo
           sapiens]
          Length = 142

 Score = 28.5 bits (62), Expect = 8.0
 Identities = 22/55 (40%), Positives = 24/55 (43%), Gaps = 2/55 (3%)

Query: 247 CSTWGLPLR--VAGSWLTVVTVEALGGWRMGVRRTGQVGPTMHPPPVSGASPLLL 299
           C+  G PL    A  WL    V AL G   G   TGQ GP    P  SG+  L L
Sbjct: 62  CAFAGRPLIDVKASGWLRRSPVGALPGAGFGAHATGQRGPHGATPLFSGSLGLQL 116


>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
          Length = 2803

 Score = 28.5 bits (62), Expect = 8.0
 Identities = 25/80 (31%), Positives = 33/80 (41%), Gaps = 12/80 (15%)

Query: 224  SSCPDYERGRRACLTLHRHPTPHCSTWG-------LPLRVAGSWLTVVTVEALGGWRMGV 276
            S+ P+ E G + C T    P PH            LP  +    L+   V  +G  R G 
Sbjct: 2425 SASPEVEAGPQGCAT---EPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVRLVG--RGGR 2479

Query: 277  RRTGQVGPTMHPPPVSGASP 296
            RR G  G T  P PV+  +P
Sbjct: 2480 RRVGGPGTTGGPCPVTDETP 2499


>gi|82546830 SEC8 protein isoform a [Homo sapiens]
          Length = 974

 Score = 28.5 bits (62), Expect = 8.0
 Identities = 15/53 (28%), Positives = 25/53 (47%)

Query: 217 LCMTLAESSCPDYERGRRACLTLHRHPTPHCSTWGLPLRVAGSWLTVVTVEAL 269
           +  TL+E +    +   R  L LH     HC  + +PL   G++  V  VE++
Sbjct: 756 IMQTLSELAKSFQDMADRCLLVLHLEVRVHCFHYLIPLAKEGNYAIVANVESM 808


>gi|150378452 heparan-alpha-glucosaminide N-acetyltransferase [Homo
           sapiens]
          Length = 635

 Score = 28.5 bits (62), Expect = 8.0
 Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 1/78 (1%)

Query: 227 PDYERGRRACLTLHRHPTPHCSTWGLPLRVAGSWLTVVTVEALGGWRMGVRRTGQVGPTM 286
           P++    R+CL+L R  T     W L L + G WL +  +  + G   G    G +G   
Sbjct: 371 PEHCASERSCLSL-RDITSSWPQWLLILVLEGLWLGLTFLLPVPGCPTGYLGPGGIGDFG 429

Query: 287 HPPPVSGASPLLLHHLLL 304
             P  +G +   +  LLL
Sbjct: 430 KYPNCTGGAAGYIDRLLL 447


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.137    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,512,943
Number of Sequences: 37866
Number of extensions: 644722
Number of successful extensions: 2233
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2223
Number of HSP's gapped (non-prelim): 25
length of query: 313
length of database: 18,247,518
effective HSP length: 102
effective length of query: 211
effective length of database: 14,385,186
effective search space: 3035274246
effective search space used: 3035274246
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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